PharmaCoNets of Salbutamol (SPCN: 46.52 )

Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Levosalbutamolhsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Levosalbutamolhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Levosalbutamolhsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Levosalbutamolhsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Levosalbutamolhsa01522Endocrine resistance2.16E-021P04049RAF1More
Levosalbutamolhsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Levosalbutamolhsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Levosalbutamolhsa04014Ras signaling pathway3.65E-021P04049RAF1More
Levosalbutamolhsa04015Rap1 signaling pathway2.99E-021P04049RAF1More
Levosalbutamolhsa04022cGMP-PKG signaling pathway3.15E-021P04049RAF1More
Levosalbutamolhsa04024cAMP signaling pathway2.49E-021P04049RAF1More
Levosalbutamolhsa04062Chemokine signaling pathway3.98E-021P04049RAF1More
Levosalbutamolhsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Levosalbutamolhsa04071Sphingolipid signaling pathway3.35E-035P04049, P21453, Q9H228, P01375, Q13362RAF1, S1PR1, EDG8, TNF, PPP2R5CMore
Levosalbutamolhsa04072Phospholipase D signaling pathway2.82E-021P04049RAF1More
Levosalbutamolhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Levosalbutamolhsa04140Autophagy - animal2.82E-021P04049RAF1More
Levosalbutamolhsa04150mTOR signaling pathway2.32E-021P04049RAF1More
Levosalbutamolhsa04210Apoptosis2.16E-021P04049RAF1More
Levosalbutamolhsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Levosalbutamolhsa04218Cellular senescence2.49E-021P04049RAF1More
Levosalbutamolhsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Levosalbutamolhsa04270Vascular smooth muscle contraction2.32E-021P04049RAF1More
Levosalbutamolhsa04360Axon guidance2.49E-021P04049RAF1More
Levosalbutamolhsa04370VEGF signaling pathway8.29E-031P04049RAF1More
Levosalbutamolhsa04371Apelin signaling pathway2.65E-021P04049RAF1More
Levosalbutamolhsa04510Focal adhesion3.48E-021P04049RAF1More
Levosalbutamolhsa04540Gap junction1.33E-021P04049RAF1More
Levosalbutamolhsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P04049RAF1More
Levosalbutamolhsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Levosalbutamolhsa04613Neutrophil extracellular trap formation5.32E-056P04049, P11215, Q13547, P58876, Q16778, O60814RAF1, ITGAM, HDAC1, H2BC5, HIST2H2BE, H2BC12More
Levosalbutamolhsa04625C-type lectin receptor signaling pathway1.49E-021P04049RAF1More
Levosalbutamolhsa04630JAK-STAT signaling pathway1.49E-021P04049RAF1More
Levosalbutamolhsa04650Natural killer cell mediated cytotoxicity2.93E-058P01375, P20963, P04049, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, RAF1, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Levosalbutamolhsa04657IL-17 signaling pathway2.41E-024P19875, P14780, P80188, P01375CXCL2, MMP9, LCN2, TNFMore
Levosalbutamolhsa04660T cell receptor signaling pathway1.66E-021P04049RAF1More
Levosalbutamolhsa04662B cell receptor signaling pathway9.95E-031P04049RAF1More
Levosalbutamolhsa04664Fc epsilon RI signaling pathway1.16E-021P04049RAF1More
Levosalbutamolhsa04666Fc gamma R-mediated phagocytosis2.32E-021P04049RAF1More
Levosalbutamolhsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Levosalbutamolhsa04720Long-term potentiation1.66E-021P04049RAF1More
Levosalbutamolhsa04722Neurotrophin signaling pathway2.32E-021P04049RAF1More
Levosalbutamolhsa04726Serotonergic synapse1.33E-021P04049RAF1More
Levosalbutamolhsa04730Long-term depression1.16E-021P04049RAF1More
Levosalbutamolhsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Levosalbutamolhsa04742Taste transduction1.01E-021P30939HTR1FMore
Levosalbutamolhsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Levosalbutamolhsa04910Insulin signaling pathway1.49E-021P04049RAF1More
Levosalbutamolhsa04912GnRH signaling pathway1.82E-021P04049RAF1More
Levosalbutamolhsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Levosalbutamolhsa04914Progesterone-mediated oocyte maturation2.16E-021P04049RAF1More
Levosalbutamolhsa04915Estrogen signaling pathway2.99E-021P04049RAF1More
Levosalbutamolhsa04916Melanogenesis1.33E-021P04049RAF1More
Levosalbutamolhsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Levosalbutamolhsa04919Thyroid hormone signaling pathway1.82E-021P04049RAF1More
Levosalbutamolhsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Levosalbutamolhsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Levosalbutamolhsa04926Relaxin signaling pathway6.24E-035P18848, P22694, P14780, P04049, P30679ATF4, PRKACB, MMP9, RAF1, GNA15More
Levosalbutamolhsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Levosalbutamolhsa04928Parathyroid hormone synthesis, secretion and action1.99E-021P04049RAF1More
Levosalbutamolhsa04929GnRH secretion4.98E-031P04049RAF1More
Levosalbutamolhsa04935Growth hormone synthesis, secretion and action2.16E-021P04049RAF1More
Levosalbutamolhsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Levosalbutamolhsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Levosalbutamolhsa05034Alcoholism1.49E-045Q13547, P04049, P58876, Q16778, O60814HDAC1, RAF1, H2BC5, HIST2H2BE, H2BC12More
Levosalbutamolhsa05132Salmonella infection4.98E-021P04049RAF1More
Levosalbutamolhsa05144Malaria1.91E-023P01375, P35443, P26718TNF, THBS4, KLRK1More
Levosalbutamolhsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Levosalbutamolhsa05152Tuberculosis3.98E-021P04049RAF1More
Levosalbutamolhsa05160Hepatitis C1.99E-021P04049RAF1More
Levosalbutamolhsa05161Hepatitis B1.99E-021P04049RAF1More
Levosalbutamolhsa05163Human cytomegalovirus infection4.98E-021P04049RAF1More
Levosalbutamolhsa05164Influenza A3.65E-021P04049RAF1More
Levosalbutamolhsa05167Kaposi sarcoma-associated herpesvirus infection3.15E-021P04049RAF1More
Levosalbutamolhsa05170Human immunodeficiency virus 1 infection3.48E-021P04049RAF1More
Levosalbutamolhsa05202Transcriptional misregulation in cancer1.24E-024P27930, P11215, Q13547, P12980IL1R2, ITGAM, HDAC1, LYL1More
Levosalbutamolhsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Levosalbutamolhsa05205Proteoglycans in cancer1.09E-026P04049, P14780, P01375, P23588, Q13635, P22694RAF1, MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Levosalbutamolhsa05206MicroRNAs in cancer3.15E-021P04049RAF1More
Levosalbutamolhsa05210Colorectal cancer1.66E-021P04049RAF1More
Levosalbutamolhsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Levosalbutamolhsa05212Pancreatic cancer1.16E-021P04049RAF1More
Levosalbutamolhsa05213Endometrial cancer9.95E-031P04049RAF1More
Levosalbutamolhsa05214Glioma9.95E-031P04049RAF1More
Levosalbutamolhsa05215Prostate cancer1.33E-021P04049RAF1More
Levosalbutamolhsa05218Melanoma6.63E-031P04049RAF1More
Levosalbutamolhsa05219Bladder cancer4.98E-031P04049RAF1More
Levosalbutamolhsa05220Chronic myeloid leukemia9.95E-031P04049RAF1More
Levosalbutamolhsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Levosalbutamolhsa05223Non-small cell lung cancer6.63E-031P04049RAF1More
Levosalbutamolhsa05224Breast cancer1.49E-021P04049RAF1More
Levosalbutamolhsa05225Hepatocellular carcinoma1.33E-021P04049RAF1More
Levosalbutamolhsa05226Gastric cancer8.29E-031P04049RAF1More
Levosalbutamolhsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Levosalbutamolhsa05231Choline metabolism in cancer1.33E-021P04049RAF1More
Levosalbutamolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.66E-021P04049RAF1More
Levosalbutamolhsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Levosalbutamolhsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Levosalbutamolhsa05332Graft-versus-host disease8.79E-033P01375, P26715, Q13241TNF, KLRC1, KLRD1More
Salbutamolhsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Salbutamolhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Salbutamolhsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Salbutamolhsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Salbutamolhsa01522Endocrine resistance2.16E-021P04049RAF1More
Salbutamolhsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Salbutamolhsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Salbutamolhsa04014Ras signaling pathway3.65E-021P04049RAF1More
Salbutamolhsa04015Rap1 signaling pathway2.99E-021P04049RAF1More
Salbutamolhsa04022cGMP-PKG signaling pathway3.15E-021P04049RAF1More
Salbutamolhsa04024cAMP signaling pathway2.49E-021P04049RAF1More
Salbutamolhsa04062Chemokine signaling pathway3.98E-021P04049RAF1More
Salbutamolhsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Salbutamolhsa04071Sphingolipid signaling pathway3.35E-035P04049, P21453, Q9H228, P01375, Q13362RAF1, S1PR1, EDG8, TNF, PPP2R5CMore
Salbutamolhsa04072Phospholipase D signaling pathway2.82E-021P04049RAF1More
Salbutamolhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Salbutamolhsa04140Autophagy - animal2.82E-021P04049RAF1More
Salbutamolhsa04150mTOR signaling pathway2.32E-021P04049RAF1More
Salbutamolhsa04210Apoptosis2.16E-021P04049RAF1More
Salbutamolhsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Salbutamolhsa04218Cellular senescence2.49E-021P04049RAF1More
Salbutamolhsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Salbutamolhsa04270Vascular smooth muscle contraction2.32E-021P04049RAF1More
Salbutamolhsa04360Axon guidance2.49E-021P04049RAF1More
Salbutamolhsa04370VEGF signaling pathway8.29E-031P04049RAF1More
Salbutamolhsa04371Apelin signaling pathway2.65E-021P04049RAF1More
Salbutamolhsa04510Focal adhesion3.48E-021P04049RAF1More
Salbutamolhsa04540Gap junction1.33E-021P04049RAF1More
Salbutamolhsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P04049RAF1More
Salbutamolhsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Salbutamolhsa04613Neutrophil extracellular trap formation5.32E-056P04049, P11215, Q13547, P58876, Q16778, O60814RAF1, ITGAM, HDAC1, H2BC5, HIST2H2BE, H2BC12More
Salbutamolhsa04625C-type lectin receptor signaling pathway1.49E-021P04049RAF1More
Salbutamolhsa04630JAK-STAT signaling pathway1.49E-021P04049RAF1More
Salbutamolhsa04650Natural killer cell mediated cytotoxicity2.93E-058P01375, P20963, P04049, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, RAF1, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Salbutamolhsa04657IL-17 signaling pathway2.41E-024P19875, P14780, P80188, P01375CXCL2, MMP9, LCN2, TNFMore
Salbutamolhsa04660T cell receptor signaling pathway1.66E-021P04049RAF1More
Salbutamolhsa04662B cell receptor signaling pathway9.95E-031P04049RAF1More
Salbutamolhsa04664Fc epsilon RI signaling pathway1.16E-021P04049RAF1More
Salbutamolhsa04666Fc gamma R-mediated phagocytosis2.32E-021P04049RAF1More
Salbutamolhsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Salbutamolhsa04720Long-term potentiation1.66E-021P04049RAF1More
Salbutamolhsa04722Neurotrophin signaling pathway2.32E-021P04049RAF1More
Salbutamolhsa04726Serotonergic synapse1.33E-021P04049RAF1More
Salbutamolhsa04730Long-term depression1.16E-021P04049RAF1More
Salbutamolhsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Salbutamolhsa04742Taste transduction1.01E-021P30939HTR1FMore
Salbutamolhsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Salbutamolhsa04910Insulin signaling pathway1.49E-021P04049RAF1More
Salbutamolhsa04912GnRH signaling pathway1.82E-021P04049RAF1More
Salbutamolhsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Salbutamolhsa04914Progesterone-mediated oocyte maturation2.16E-021P04049RAF1More
Salbutamolhsa04915Estrogen signaling pathway2.99E-021P04049RAF1More
Salbutamolhsa04916Melanogenesis1.33E-021P04049RAF1More
Salbutamolhsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Salbutamolhsa04919Thyroid hormone signaling pathway1.82E-021P04049RAF1More
Salbutamolhsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Salbutamolhsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Salbutamolhsa04926Relaxin signaling pathway6.24E-035P18848, P22694, P14780, P04049, P30679ATF4, PRKACB, MMP9, RAF1, GNA15More
Salbutamolhsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Salbutamolhsa04928Parathyroid hormone synthesis, secretion and action1.99E-021P04049RAF1More
Salbutamolhsa04929GnRH secretion4.98E-031P04049RAF1More
Salbutamolhsa04935Growth hormone synthesis, secretion and action2.16E-021P04049RAF1More
Salbutamolhsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Salbutamolhsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Salbutamolhsa05034Alcoholism1.49E-045Q13547, P04049, P58876, Q16778, O60814HDAC1, RAF1, H2BC5, HIST2H2BE, H2BC12More
Salbutamolhsa05132Salmonella infection4.98E-021P04049RAF1More
Salbutamolhsa05144Malaria1.91E-023P01375, P35443, P26718TNF, THBS4, KLRK1More
Salbutamolhsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Salbutamolhsa05152Tuberculosis3.98E-021P04049RAF1More
Salbutamolhsa05160Hepatitis C1.99E-021P04049RAF1More
Salbutamolhsa05161Hepatitis B1.99E-021P04049RAF1More
Salbutamolhsa05163Human cytomegalovirus infection4.98E-021P04049RAF1More
Salbutamolhsa05164Influenza A3.65E-021P04049RAF1More
Salbutamolhsa05167Kaposi sarcoma-associated herpesvirus infection3.15E-021P04049RAF1More
Salbutamolhsa05170Human immunodeficiency virus 1 infection3.48E-021P04049RAF1More
Salbutamolhsa05202Transcriptional misregulation in cancer1.24E-024P27930, P11215, Q13547, P12980IL1R2, ITGAM, HDAC1, LYL1More
Salbutamolhsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Salbutamolhsa05205Proteoglycans in cancer1.09E-026P04049, P14780, P01375, P23588, Q13635, P22694RAF1, MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Salbutamolhsa05206MicroRNAs in cancer3.15E-021P04049RAF1More
Salbutamolhsa05210Colorectal cancer1.66E-021P04049RAF1More
Salbutamolhsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Salbutamolhsa05212Pancreatic cancer1.16E-021P04049RAF1More
Salbutamolhsa05213Endometrial cancer9.95E-031P04049RAF1More
Salbutamolhsa05214Glioma9.95E-031P04049RAF1More
Salbutamolhsa05215Prostate cancer1.33E-021P04049RAF1More
Salbutamolhsa05218Melanoma6.63E-031P04049RAF1More
Salbutamolhsa05219Bladder cancer4.98E-031P04049RAF1More
Salbutamolhsa05220Chronic myeloid leukemia9.95E-031P04049RAF1More
Salbutamolhsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Salbutamolhsa05223Non-small cell lung cancer6.63E-031P04049RAF1More
Salbutamolhsa05224Breast cancer1.49E-021P04049RAF1More
Salbutamolhsa05225Hepatocellular carcinoma1.33E-021P04049RAF1More
Salbutamolhsa05226Gastric cancer8.29E-031P04049RAF1More
Salbutamolhsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Salbutamolhsa05231Choline metabolism in cancer1.33E-021P04049RAF1More
Salbutamolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.66E-021P04049RAF1More
Salbutamolhsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Salbutamolhsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Salbutamolhsa05332Graft-versus-host disease8.79E-033P01375, P26715, Q13241TNF, KLRC1, KLRD1More

Community members of Salbutamol (SDC: 3.53)

UniProtACGene NameProtein NameReported/
Predicted
DisGeNETSPVSdrugabilitySHiSBiNSDisG
P07550ADRB2BetaNone2 adrenergic receptorReported00.007110.22052.224
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
ADRB2P07550IC50980
ADRB2P07550IC501995
ADRB2P07550Ki501.19
ADRB2P07550Ki510
ADRB2P07550Ki1828
ADRB2P07550Kd759
ADRB2P07550Ki3802
ADRB2P07550Ki4677
ADRB2P07550Ki5623