PharmaCoNets of Norethisterone (SPCN: 138.74 )

Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Norethisteronehsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Norethisteronehsa00030Pentose phosphate pathway3.67E-033P60891, P11413, P37837PRPS1, G6PD, TALDO1More
Norethisteronehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Norethisteronehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Norethisteronehsa00071Fatty acid degradation3.77E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Norethisteronehsa00190Oxidative phosphorylation9.21E-053Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Norethisteronehsa00480Glutathione metabolism1.35E-021P11413G6PDMore
Norethisteronehsa00500Starch and sucrose metabolism1.00E-033O43451, P46976, P06737MGAM, GYG1, PYGLMore
Norethisteronehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Norethisteronehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Norethisteronehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Norethisteronehsa00600Sphingolipid metabolism3.76E-021P15289ARSAMore
Norethisteronehsa00630Glyoxylate and dicarboxylate metabolism1.88E-052P40925, P15104MDH1, GLULMore
Norethisteronehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Norethisteronehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Norethisteronehsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Norethisteronehsa00970Aminoacyl-tRNA biosynthesis2.34E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Norethisteronehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Norethisteronehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Norethisteronehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Norethisteronehsa01200Carbon metabolism2.91E-021P11413G6PDMore
Norethisteronehsa012102-Oxocarboxylic acid metabolism3.43E-021P50213IDH3AMore
Norethisteronehsa01230Biosynthesis of amino acids3.27E-035P51854, P60891, Q99707, P50213, P37837TKTL1, PRPS1, MTR, IDH3A, TALDO1More
Norethisteronehsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P08069IGF1RMore
Norethisteronehsa01522Endocrine resistance2.16E-021P08069IGF1RMore
Norethisteronehsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Norethisteronehsa03008Ribosome biogenesis in eukaryotes2.40E-035P19784, P67870, O14980, O60832, Q9BVP2CSNK2A2, CSNK2B, XPO1, DKC1, GNL3More
Norethisteronehsa03013RNA transport2.35E-0510O14980, P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, Q14240, P23588, Q9Y6A5XPO1, NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF4A2, EIF4B, TACC3More
Norethisteronehsa03040Spliceosome5.82E-048Q14562, O43143, O60508, P08579, Q07955, Q01130, Q13243, Q9Y2W2DHX8, DHX15, CDC40, SNRPB2, SFRS1, SFRS2, SFRS5, WBP11More
Norethisteronehsa03430Mismatch repair4.38E-021P20585MSH3More
Norethisteronehsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Norethisteronehsa04010MAPK signaling pathway4.15E-021P08069IGF1RMore
Norethisteronehsa04014Ras signaling pathway9.02E-036P42338, P20827, P49767, P08069, Q13009, P50151PIK3CB, EFNA1, VEGFC, IGF1R, TIAM1, GNG10More
Norethisteronehsa04015Rap1 signaling pathway5.18E-043P08069, P06213, O00522IGF1R, INSR, KRIT1More
Norethisteronehsa04024cAMP signaling pathway4.25E-037P63092, P42338, P26678, P0DP23, P61586, Q13370, Q13009GNAS, PIK3CB, PLN, CALM1, RHOA, PDE3B, TIAM1More
Norethisteronehsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, P25025, P14784CXCL1, CXCL2, CXCR1, CXCR2, IL2RBMore
Norethisteronehsa04062Chemokine signaling pathway1.83E-028P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10More
Norethisteronehsa04064NF-kappa B signaling pathway7.27E-0411Q13489, Q13546, P14778, P19174, Q04759, Q9UDY8, P06239, P09341, P19875, Q06643, Q9UNE0BIRC3, RIPK1, IL1R1, PLCG1, PRKCQ, MALT1, LCK, CXCL1, CXCL2, LTB, EDARMore
Norethisteronehsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Norethisteronehsa04068FoxO signaling pathway1.99E-021P08069IGF1RMore
Norethisteronehsa04070Phosphatidylinositol signaling system4.86E-023P0DP23, P42338, P27987CALM1, PIK3CB, ITPKBMore
Norethisteronehsa04071Sphingolipid signaling pathway1.94E-023Q9H228, P01375, Q9UQC2EDG8, TNF, GAB2More
Norethisteronehsa04072Phospholipase D signaling pathway5.37E-038P42338, P61586, P43657, P25024, P25025, P19174, O14986, P63092PIK3CB, RHOA, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, GNASMore
Norethisteronehsa04080Neuroactive ligand-receptor interaction3.70E-027P08311, P48058, Q15722, Q9H228, P43657, P21730, P35318CTSG, GRIA4, LTB4R, EDG8, P2RY5, C5AR1, ADMMore
Norethisteronehsa04114Oocyte meiosis3.19E-035P51812, Q02750, P16298, Q17RY0, P08069RPS6KA3, MAP2K1, PPP3CB, CPEB4, IGF1RMore
Norethisteronehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Norethisteronehsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Norethisteronehsa04137Mitophagy - animal2.52E-022P19784, P67870CSNK2A2, CSNK2BMore
Norethisteronehsa04140Autophagy - animal2.82E-021P08069IGF1RMore
Norethisteronehsa04141Protein processing in endoplasmic reticulum2.78E-023P07384, O95487, O95816CAPN1, SEC24B, BAG2More
Norethisteronehsa04150mTOR signaling pathway7.74E-034P08069, Q02750, Q9NQL2, P51812IGF1R, MAP2K1, RRAGD, RPS6KA3More
Norethisteronehsa04151PI3K-Akt signaling pathway1.14E-028P42338, P43657, P20827, P49767, P50151, O15335, Q13751, P14784PIK3CB, P2RY5, EFNA1, VEGFC, GNG10, CHAD, LAMB3, IL2RBMore
Norethisteronehsa04152AMPK signaling pathway1.99E-021P08069IGF1RMore
Norethisteronehsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Norethisteronehsa04211Longevity regulating pathway1.34E-034Q12778, P08069, Q9UEF7, Q96KQ7FOXO1, IGF1R, KL, EHMT2More
Norethisteronehsa04213Longevity regulating pathway - multiple species1.14E-035P42338, P08069, Q9Y4H2, P11142, Q13547PIK3CB, IGF1R, IRS2, HSPA8, HDAC1More
Norethisteronehsa04217Necroptosis2.34E-0513P01375, P01568, P48023, Q13489, Q13546, P42224, Q14765, P08238, Q6FI13, Q99878, Q93077, O43633, Q08752TNF, IFNA21, FASLG, BIRC3, RIPK1, STAT1, STAT4, HSP90AB1, H2AC18; H2AC19, H2AC14, HIST1H2AC, CHMP2A, PPIDMore
Norethisteronehsa04310Wnt signaling pathway4.17E-033P61586, P19784, P67870RHOA, CSNK2A2, CSNK2BMore
Norethisteronehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Norethisteronehsa04360Axon guidance7.48E-045P20827, O95631, P42338, P23528, Q06124EFNA1, NTN1, PIK3CB, CFL1, PTPN11More
Norethisteronehsa04370VEGF signaling pathway2.68E-033P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Norethisteronehsa04510Focal adhesion8.84E-034O14986, P61586, Q16363, P08069PIP5K1B, RHOA, LAMA4, IGF1RMore
Norethisteronehsa04520Adherens junction1.65E-054P08069, P19784, P67870, P61586IGF1R, CSNK2A2, CSNK2B, RHOAMore
Norethisteronehsa04530Tight junction1.74E-036P63261, P16989, P56750, Q9Y478, Q92974, Q14247ACTG1, CSDA, CLDN17, PRKAB1, ARHGEF2, CTTNMore
Norethisteronehsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P08069IGF1RMore
Norethisteronehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Norethisteronehsa04613Neutrophil extracellular trap formation1.02E-048P11215, Q13547, Q93077, P58876, P62807, Q16778, O60814, P68431ITGAM, HDAC1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Norethisteronehsa04620Toll-like receptor signaling pathway4.16E-022Q13546, P01568RIPK1, IFNA21More
Norethisteronehsa04621NOD-like receptor signaling pathway4.72E-023P01568, Q13489, Q13546IFNA21, BIRC3, RIPK1More
Norethisteronehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Norethisteronehsa04623Cytosolic DNA-sensing pathway2.63E-043P01568, Q13546, P25963IFNA21, RIPK1, NFKBIAMore
Norethisteronehsa04640Hematopoietic cell lineage4.78E-0411P13612, P14778, P27930, P11215, P15144, P25063, P07766, P09693, P01732, P01730, P09564ITGA4, IL1R1, IL1R2, ITGAM, ANPEP, CD24, CD3E, CD3G, CD8A, CD4, CD7More
Norethisteronehsa04650Natural killer cell mediated cytotoxicity8.24E-0715P16298, P50591, P19174, P78314, P06239, O60880, P20963, P42338, Q02750, Q13241, P26718, O14931, O75015, P26717, P26715PPP3CB, TNFSF10, PLCG1, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC1More
Norethisteronehsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Norethisteronehsa04658Th1 and Th2 cell differentiation9.26E-0812Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P23771, Q9UL17, P14784, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, GATA3, TBX21, IL2RB, RUNX3More
Norethisteronehsa04659Th17 cell differentiation1.51E-0715Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P14778, P40189, Q9UL17, P23771, P08238, P07766, P09693, P20963PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, IL1R1, IL6ST, TBX21, GATA3, HSP90AB1, CD3E, CD3G, CD247More
Norethisteronehsa04660T cell receptor signaling pathway7.40E-0612Q04759, P42338, P19174, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, Q16539, P49841PRKCQ, PIK3CB, PLCG1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Norethisteronehsa04662B cell receptor signaling pathway9.78E-045P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Norethisteronehsa04664Fc epsilon RI signaling pathway1.82E-023P42338, P07948, P09917PIK3CB, LYN, ALOX5More
Norethisteronehsa04666Fc gamma R-mediated phagocytosis3.08E-023P42338, P23528, P14598PIK3CB, CFL1, NCF1More
Norethisteronehsa04713Circadian entrainment4.94E-022P62873, P63092GNB1, GNASMore
Norethisteronehsa04714Thermogenesis1.25E-023P15336, P63261, Q9Y478ATF2, ACTG1, PRKAB1More
Norethisteronehsa04720Long-term potentiation1.38E-023P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Norethisteronehsa04721Synaptic vesicle cycle9.45E-042Q13488, P31645TCIRG1, SLC6A4More
Norethisteronehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Norethisteronehsa04723Retrograde endocannabinoid signaling4.94E-022P48169, P62873GABRA4, GNB1More
Norethisteronehsa04724Glutamatergic synapse2.85E-035P43003, P63092, P62873, P50151, P15104SLC1A3, GNAS, GNB1, GNG10, GLULMore
Norethisteronehsa04726Serotonergic synapse2.52E-022P63092, P62873GNAS, GNB1More
Norethisteronehsa04730Long-term depression1.16E-021P08069IGF1RMore
Norethisteronehsa04750Inflammatory mediator regulation of TRP channels7.24E-035P14778, P19174, P42338, P24723, Q04759IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQMore
Norethisteronehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Norethisteronehsa04913Ovarian steroidogenesis8.40E-042P06213, P08069INSR, IGF1RMore
Norethisteronehsa04914Progesterone-mediated oocyte maturation9.67E-047P08069, Q17RY0, P42338, Q13370, P08238, P51812, Q02750IGF1R, CPEB4, PIK3CB, PDE3B, HSP90AB1, RPS6KA3, MAP2K1More
Norethisteronehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Norethisteronehsa04920Adipocytokine signaling pathway2.80E-022Q06124, Q9Y478PTPN11, PRKAB1More
Norethisteronehsa04923Regulation of lipolysis in adipocytes4.24E-034P07550, P06213, P42338, Q9Y4H2ADRB2, INSR, PIK3CB, IRS2More
Norethisteronehsa04924Renin secretion3.77E-022Q13370, P0DP23PDE3B, CALM1More
Norethisteronehsa04930Type II diabetes mellitus3.14E-021P06213INSRMore
Norethisteronehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Norethisteronehsa04932Non-alcoholic fatty liver disease2.74E-023P01375, P49841, P48023TNF, GSK3B, FASLGMore
Norethisteronehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Norethisteronehsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Norethisteronehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Norethisteronehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Norethisteronehsa04972Pancreatic secretion3.65E-022P63092, P61586GNAS, RHOAMore
Norethisteronehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Norethisteronehsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Norethisteronehsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Norethisteronehsa05032Morphine addiction2.47E-033P62873, P48169, P63092GNB1, GABRA4, GNASMore
Norethisteronehsa05034Alcoholism2.05E-057Q13547, Q93077, P58876, P62807, Q16778, O60814, P68431HDAC1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Norethisteronehsa05120Epithelial cell signaling in Helicobacter pylori infection3.32E-046Q16539, P09341, P19875, P19174, P25024, P25025MAPK14, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Norethisteronehsa05130Pathogenic Escherichia coli infection9.80E-034Q92974, P63261, Q06124, O95487ARHGEF2, ACTG1, PTPN11, SEC24BMore
Norethisteronehsa05132Salmonella infection9.85E-034Q13546, Q13489, O60282, P68371RIPK1, BIRC3, KIF5C, TUBB2CMore
Norethisteronehsa05133Pertussis4.20E-021P0C0L4C4AMore
Norethisteronehsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Norethisteronehsa05135Yersinia infection1.52E-026P13612, P06239, Q16539, P49841, P01730, P01732ITGA4, LCK, MAPK14, GSK3B, CD4, CD8AMore
Norethisteronehsa05140Leishmaniasis2.18E-046P14598, P42224, O60603, P25963, P29350, Q15080NCF1, STAT1, TLR2, NFKBIA, PTPN6, NCF4More
Norethisteronehsa05143African trypanosomiasis7.50E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Norethisteronehsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Norethisteronehsa05146Amoebiasis2.36E-059P09341, P19875, P14778, P27930, P42338, P11215, P05089, P12814, P08311CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, ACTN1, CTSGMore
Norethisteronehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Norethisteronehsa05163Human cytomegalovirus infection2.09E-024P62873, P61586, P63092, P61769GNB1, RHOA, GNAS, B2MMore
Norethisteronehsa05167Kaposi sarcoma-associated herpesvirus infection1.94E-024P62879, P16298, Q02750, P0CG47GNB2, PPP3CB, MAP2K1, UBBMore
Norethisteronehsa05168Herpes simplex virus 1 infection1.38E-0415P25963, P01568, Q05823, P42224, Q07955, Q01130, Q13243, Q13489, P42338, Q13398, Q9HCX3, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, RNASEL, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PIK3CB, ZNF211, ZNF304, ZNF85, ZNF140, ZNF189, ZNF212More
Norethisteronehsa05170Human immunodeficiency virus 1 infection6.02E-035Q02750, P62879, P16298, Q05397, P20333MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1BMore
Norethisteronehsa05200Pathways in cancer3.92E-029P42338, P08238, P42224, P43246, P14923, O75293, P0DP23, P14784, P40189PIK3CB, HSP90AB1, STAT1, MSH2, JUP, GADD45B, CALM1, IL2RB, IL6STMore
Norethisteronehsa05202Transcriptional misregulation in cancer8.55E-045P27930, P11215, P08069, Q13547, P12980IL1R2, ITGAM, IGF1R, HDAC1, LYL1More
Norethisteronehsa05203Viral carcinogenesis1.22E-036Q13547, Q15283, P58876, P62807, Q16778, O60814HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12More
Norethisteronehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Norethisteronehsa05205Proteoglycans in cancer3.48E-021P08069IGF1RMore
Norethisteronehsa05211Renal cell carcinoma1.06E-022Q06124, Q99814PTPN11, EPAS1More
Norethisteronehsa05212Pancreatic cancer1.72E-023P42338, P42224, O75293PIK3CB, STAT1, GADD45BMore
Norethisteronehsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Norethisteronehsa05214Glioma1.88E-034P08069, P0DP23, P42338, O75293IGF1R, CALM1, PIK3CB, GADD45BMore
Norethisteronehsa05215Prostate cancer1.33E-021P08069IGF1RMore
Norethisteronehsa05218Melanoma6.63E-031P08069IGF1RMore
Norethisteronehsa05224Breast cancer1.49E-021P08069IGF1RMore
Norethisteronehsa05225Hepatocellular carcinoma1.33E-021P08069IGF1RMore
Norethisteronehsa05226Gastric cancer3.79E-022Q02750, O15169MAP2K1, AXIN1More
Norethisteronehsa05230Central carbon metabolism in cancer1.12E-021P11413G6PDMore
Norethisteronehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.18E-049P42338, P19174, P07766, P20963, P09693, P06239, Q04759, Q16539, P01730PIK3CB, PLCG1, CD3E, CD247, CD3G, LCK, PRKCQ, MAPK14, CD4More
Norethisteronehsa05322Systemic lupus erythematosus4.80E-067P09871, Q93077, P58876, P62807, Q16778, O60814, P68431C1S, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Norethisteronehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Norethisteronehsa05332Graft-versus-host disease3.70E-022P48023, P01375FASLG, TNFMore
Norethisteronehsa05340Primary immunodeficiency3.76E-024P01730, P01732, P07766, P06239CD4, CD8A, CD3E, LCKMore
Norethisteronehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Norethisteronehsa05415Diabetic cardiomyopathy7.96E-037P17252, P14598, Q15080, Q16718, O14521, P04406, P11413PRKCA, NCF1, NCF4, NDUFA5, SDHD, GAPDH, G6PDMore
Norethisteronehsa05418Fluid shear stress and atherosclerosis3.73E-024P42338, P14598, P0DP23, P08238PIK3CB, NCF1, CALM1, HSP90AB1More

Community members of Norethisterone (SDC: 7.87)

UniProtACGene NameProtein NameReported/
Predicted
DisGeNETSPVSdrugabilitySHiSBiNSDisG
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
P11413G6PDGlucoseNone6Nonephosphate 1NonedehydrogenasePredicted10.44350.63690.29291.7884
Q06124PTPN11TyrosineNoneprotein phosphatase nonNonereceptor type 11Predicted10.15130.45660.6131.6017
P48169GABRA4GammaNoneaminobutyric acid receptor subunit alphaNone4Predicted00.32530.5650.15791.4506
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
O43451MGAMMaltaseNoneglucoamylasePredicted10.19540.16780.1910.6242
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
P35610SOAT1Sterol ONoneacyltransferase 1Predicted10.38550.29360.01650.7964
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P09960LTA4HLeukotriene ANone4 hydrolasePredicted00.2770.95190.15652.1988
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)