PharmaCoNets of Glipizide (SPCN: 227.63 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Glipizidehsa00030Pentose phosphate pathway9.42E-063P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Glipizidehsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Glipizidehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Glipizidehsa00062Fatty acid elongation3.94E-021Q9H5J4ELOVL6More
Glipizidehsa00071Fatty acid degradation3.50E-024O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Glipizidehsa00190Oxidative phosphorylation4.86E-043Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Glipizidehsa00220Arginine biosynthesis3.38E-053P15104, P05089, P49448GLUL, ARG1, GLUD2More
Glipizidehsa00250Alanine, aspartate and glutamate metabolism2.42E-021P15104GLULMore
Glipizidehsa00280Valine, leucine and isoleucine degradation1.67E-024P55809, Q9HCC0, Q02252, P11310OXCT1, MCCC2, ALDH6A1, ACADMMore
Glipizidehsa00380Tryptophan metabolism1.33E-022P46952, P51648HAAO, ALDH3A2More
Glipizidehsa00500Starch and sucrose metabolism5.75E-063O43451, P46976, P06737MGAM, GYG1, PYGLMore
Glipizidehsa00510N-Glycan biosynthesis3.61E-022P15907, Q9NR34ST6GAL1, MAN1C1More
Glipizidehsa00513Various types of N-glycan biosynthesis4.83E-021Q9NR34MAN1C1More
Glipizidehsa00520Amino sugar and nucleotide sugar metabolism2.24E-023Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Glipizidehsa00561Glycerolipid metabolism2.21E-023O14494, P06280, P23743PLPP1, GLA, DGKAMore
Glipizidehsa00562Inositol phosphate metabolism1.91E-023P27987, Q13572, Q96PE3ITPKB, ITPK1, INPP4AMore
Glipizidehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Glipizidehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Glipizidehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Glipizidehsa00600Sphingolipid metabolism3.96E-023Q9BX95, O14494, P06280SGPP1, PLPP1, GLAMore
Glipizidehsa00630Glyoxylate and dicarboxylate metabolism1.42E-044P40925, P40926, P05166, P15104MDH1, MDH2, PCCB, GLULMore
Glipizidehsa00670One carbon pool by folate1.33E-022P04818, Q99707TYMS, MTRMore
Glipizidehsa00730Thiamine metabolism1.06E-042P05186, P24666ALPL, ACP1More
Glipizidehsa00750Vitamin B6 metabolism3.56E-021O00764PDXKMore
Glipizidehsa00830Retinol metabolism2.27E-035P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Glipizidehsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Glipizidehsa00900Terpenoid backbone biosynthesis4.22E-022P49354, Q9UHG3FNTA, PCYOX1More
Glipizidehsa00910Nitrogen metabolism2.66E-033P22748, P15104, P49448CA4, GLUL, GLUD2More
Glipizidehsa00970Aminoacyl-tRNA biosynthesis2.12E-021P14868DARSMore
Glipizidehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Glipizidehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Glipizidehsa00983Drug metabolism - other enzymes2.65E-033P04183, P32320, P05164TK1, CDA, MPOMore
Glipizidehsa01040Biosynthesis of unsaturated fatty acids2.13E-032P22307, Q9H5J4SCP2, ELOVL6More
Glipizidehsa01100Metabolic pathways5.18E-0335Q9NR34, P05089, O14521, P15144, O14732, P32320, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, O60701, Q9HCC0, P33121, P42330, P51854, Q08477, Q96EB6, P15907, P57054, Q9UNP4, Q9BX95, P37837, P32321, P60891, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q16718MAN1C1, ARG1, SDHD, ANPEP, IMPA2, CDA, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, UGDH, MCCC2, ACSL1, AKR1C3, TKTL1, CYP4F3, SIRT1, ST6GAL1, PIGP, ST3GAL5, SGPP1, TALDO1, DCTD, PRPS1, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, NDUFA5More
Glipizidehsa012102-Oxocarboxylic acid metabolism3.56E-021P50213IDH3AMore
Glipizidehsa01212Fatty acid metabolism2.13E-032Q9H5J4, P22307ELOVL6, SCP2More
Glipizidehsa01230Biosynthesis of amino acids1.90E-034P60891, Q99707, P15104, P37837PRPS1, MTR, GLUL, TALDO1More
Glipizidehsa01240Biosynthesis of cofactors2.95E-022P13716, P14618ALAD, PKM2More
Glipizidehsa01522Endocrine resistance4.56E-045P14780, P22694, Q9UM47, P10415, Q13323MMP9, PRKACB, NOTCH3, BCL2, BIKMore
Glipizidehsa01523Antifolate resistance1.68E-022Q92820, P04818GGH, TYMSMore
Glipizidehsa02010ABC transporters2.17E-031Q8IZY2ABCA7More
Glipizidehsa03008Ribosome biogenesis in eukaryotes6.80E-056Q9NYH9, O14980, O60832, P78345, Q9BVP2, Q9GZY0UTP6, XPO1, DKC1, RPP38, GNL3, NXF2; NXF2BMore
Glipizidehsa03013RNA transport7.75E-1023P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q9GZY0, Q7Z3B4, P35658, P63279, P68104, Q14152, P55884, O75822, P78345, Q9H777, Q14240, P23588, Q9Y6A5, P51114, Q53GS7RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, NXF2; NXF2B, NUP54, NUP214, UBE2I, EEF1A1, EIF3A, EIF3B, EIF3J, RPP38, ELAC1, EIF4A2, EIF4B, TACC3, FXR1, GLE1More
Glipizidehsa03015mRNA surveillance pathway9.78E-036O43148, Q16537, P61326, Q9GZY0, P52298, Q53GS7RNMT, PPP2R5E, MAGOH, NXF2; NXF2B, NCBP2, GLE1More
Glipizidehsa03020RNA polymerase2.01E-065P30876, P24928, P62487, Q9GZM3, P52435POLR2B, POLR2A, POLR2G, POLR2J2, POLR2JMore
Glipizidehsa03040Spliceosome2.54E-0310Q14562, O43143, O60508, P08579, O75940, O75494, Q07955, Q01130, Q13243, O43447DHX8, DHX15, CDC40, SNRPB2, SMNDC1, FUSIP1, SFRS1, SFRS2, SFRS5, PPIHMore
Glipizidehsa03050Proteasome4.83E-021P55036PSMD4More
Glipizidehsa03060Protein export1.05E-044Q15070, P37108, O76094, Q15005OXA1L, SRP14, SRP72, SPCS2More
Glipizidehsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Glipizidehsa04012ErbB signaling pathway6.16E-034Q13153, P16333, P19174, P01106PAK1, NCK1, PLCG1, MYCMore
Glipizidehsa04014Ras signaling pathway1.70E-027P20827, Q9NRA1, P49767, P17252, P0DP23, P62873, P19174EFNA1, PDGFC, VEGFC, PRKCA, CALM1, GNB1, PLCG1More
Glipizidehsa04015Rap1 signaling pathway4.92E-039P20827, Q9NRA1, P49767, P25116, Q8TEU7, P0DP23, P08514, P17252, P19174EFNA1, PDGFC, VEGFC, F2R, RAPGEF6, CALM1, ITGA2B, PRKCA, PLCG1More
Glipizidehsa04020Calcium signaling pathway7.21E-0617P27987, Q96DU7, Q08828, Q16566, Q13557, P17252, P21860, P30679, O15399, P19174, P0DP23, P0DP24, P05141, P20020, P23634, Q9NRA1, P49767ITPKB, ITPKC, ADCY1, CAMK4, CAMK2D, PRKCA, ERBB3, GNA15, GRIN2D, PLCG1, CALM1, CALM2, SLC25A5, ATP2B1, ATP2B4, PDGFC, VEGFCMore
Glipizidehsa04022cGMP-PKG signaling pathway1.08E-039P24844, Q02153, Q99941, P18848, Q8WYR1, Q08828, P05141, Q15746, P0DP24MYL9, GUCY1B3, CREBL1, ATF4, PIK3R5, ADCY1, SLC25A5, MYLK, CALM2More
Glipizidehsa04024cAMP signaling pathway1.91E-034P48058, P25116, P24844, Q13153GRIA4, F2R, MYL9, PAK1More
Glipizidehsa04060Cytokine-cytokine receptor interaction7.03E-0516P14784, P27930, P14778, P08476, P26842, Q06643, Q13651, Q9HBE5, P25024, Q9UBD3, P47992, P01375, P09341, P18510, P01730, Q93038IL2RB, IL1R2, IL1R1, INHBA, CD27, LTB, IL10RA, IL21R, CXCR1, XCL2, XCL1, TNF, CXCL1, IL1RN, CD4, TNFRSF25More
Glipizidehsa04061Viral protein interaction with cytokine and cytokine receptor2.25E-0511Q8NHW4, P09341, P19875, P25024, P25025, P61073, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCL2, CXCR1, CXCR2, CXCR4, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Glipizidehsa04062Chemokine signaling pathway4.01E-0413P25024, P25025, P09341, P19875, P47992, Q9UBD3, P07948, P42338, P19174, P63218, P50151, P43250, Q08881CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, ITKMore
Glipizidehsa04064NF-kappa B signaling pathway4.44E-1927P10415, Q13489, P25963, P51617, O00463, Q13546, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, P67870, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9UNE0, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, CSNK2B, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, EDAR, CYLDMore
Glipizidehsa04070Phosphatidylinositol signaling system4.40E-024P19174, P0DP23, P23743, P17252PLCG1, CALM1, DGKA, PRKCAMore
Glipizidehsa04071Sphingolipid signaling pathway5.96E-1111P17252, P21453, Q9H228, P01375, Q13362, Q16537, Q9BX95, Q16539, P04637, P10415, Q9UQC2PRKCA, S1PR1, EDG8, TNF, PPP2R5C, PPP2R5E, SGPP1, MAPK14, TP53, BCL2, GAB2More
Glipizidehsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Glipizidehsa04080Neuroactive ligand-receptor interaction1.63E-069P08311, Q15722, P21453, Q9H228, O00398, P21462, P21730, Q16581, P07550CTSG, LTB4R, S1PR1, EDG8, P2RY10, FPR1, C5AR1, C3AR1, ADRB2More
Glipizidehsa04110Cell cycle8.83E-058Q9UBD5, P06493, O60566, Q14683, P30304, P33981, P42773, P01106ORC3, CDK1, BUB1B, SMC1A, CDC25A, TTK, CDKN2C, MYCMore
Glipizidehsa04115p53 signaling pathway3.57E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Glipizidehsa04120Ubiquitin mediated proteolysis4.82E-032Q9UBT2, Q14669SAE2, TRIP12More
Glipizidehsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Glipizidehsa04140Autophagy - animal5.69E-045P22694, Q14643, P10415, Q9H1Y0, Q04759PRKACB, ITPR1, BCL2, ATG5, PRKCQMore
Glipizidehsa04141Protein processing in endoplasmic reticulum3.96E-027P18848, Q15436, Q99941, P11142, Q9H3Z4, P07900, Q9NR31ATF4, SEC23A, CREBL1, HSPA8, DNAJC5, HSP90AA1, SAR1AMore
Glipizidehsa04142Lysosome2.45E-039Q99437, P25774, P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916ATP6V0B, CTSS, HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2More
Glipizidehsa04144Endocytosis2.89E-038P0DMV8, Q9H444, O75351, P62491, Q96B97, Q15438, Q14161, Q9UMY4HSPA1A, CHMP4B, VPS4B, RAB11A, SH3KBP1, PSCD1, GIT2, SNX12More
Glipizidehsa04145Phagosome8.61E-0915O75015, P60709, P63261, Q15075, Q15080, P14598, Q13509, P68371, Q13488, Q99437, P05164, O60603, P35443, P13765, P25774FCGR3B, ACTB, ACTG1, EEA1, NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, ATP6V0B, MPO, TLR2, THBS4, HLA-DOB, CTSSMore
Glipizidehsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Glipizidehsa04151PI3K-Akt signaling pathway2.21E-0210P62753, P21860, P27348, P07900, P62873, P61952, Q16363, P22105, Q99941, P18848RPS6, ERBB3, YWHAQ, HSP90AA1, GNB1, GNG11, LAMA4, TNXB, CREBL1, ATF4More
Glipizidehsa04210Apoptosis1.54E-0311Q13315, P10415, Q13489, O76075, P25963, P01375, P24522, Q16548, Q13077, P43234, Q14643ATM, BCL2, BIRC3, DFFB, NFKBIA, TNF, GADD45A, BCL2A1, TRAF1, CTSO, ITPR1More
Glipizidehsa04211Longevity regulating pathway1.18E-023Q12778, Q9UEF7, Q96KQ7FOXO1, KL, EHMT2More
Glipizidehsa04213Longevity regulating pathway - multiple species2.70E-037P42338, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547PIK3CB, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Glipizidehsa04217Necroptosis1.94E-0415P01568, Q13489, Q13546, P42224, P07900, P08238, P15104, P05141, P01584, P0C0S5, Q6FI13, Q93077, Q13557, O43633, Q08752IFNA21, BIRC3, RIPK1, STAT1, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, HIST1H2AC, CAMK2D, CHMP2A, PPIDMore
Glipizidehsa04260Cardiac muscle contraction4.49E-023P67936, P13073, P12074TPM4, COX4I1, COX6A1More
Glipizidehsa04270Vascular smooth muscle contraction9.00E-058Q15746, P24844, P0DP23, Q08828, P51828, P35579, P35749, P35318MYLK, MYL9, CALM1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Glipizidehsa04340Hedgehog signaling pathway7.38E-064P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Glipizidehsa04360Axon guidance1.43E-037P16333, P20827, O95631, P17252, P23528, P19174, Q06124NCK1, EFNA1, NTN1, PRKCA, CFL1, PLCG1, PTPN11More
Glipizidehsa04371Apelin signaling pathway3.00E-039P62873, P63218, P61952, Q08828, Q14344, Q13485, P62753, Q16566, P0DP24GNB1, GNG5, GNG11, ADCY1, GNA13, SMAD4, RPS6, CAMK4, CALM2More
Glipizidehsa04380Osteoclast differentiation9.58E-0513Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Glipizidehsa04390Hippo signaling pathway2.30E-023P63261, P04628, O43623ACTG1, WNT1, SNAI2More
Glipizidehsa04392Hippo signaling pathway - multiple species1.51E-021Q13153PAK1More
Glipizidehsa04510Focal adhesion3.36E-023P08514, Q15746, P24844ITGA2B, MYLK, MYL9More
Glipizidehsa04512ECM-receptor interaction9.97E-044P07359, P26012, P08514, P16070GP1BA, ITGB8, ITGA2B, CD44More
Glipizidehsa04514Cell adhesion molecules4.65E-022P16109, O00501SELP, CLDN5More
Glipizidehsa04530Tight junction1.14E-046Q8TEU7, P16989, P56750, O00501, Q14247, P24844RAPGEF6, CSDA, CLDN17, CLDN5, CTTN, MYL9More
Glipizidehsa04540Gap junction1.27E-046P17252, P22694, Q13509, P68371, Q9NRA1, Q14643PRKCA, PRKACB, TUBB3, TUBB2C, PDGFC, ITPR1More
Glipizidehsa04550Signaling pathways regulating pluripotency of stem cells1.96E-023P04628, P40189, P14653WNT1, IL6ST, HOXB1More
Glipizidehsa04610Complement and coagulation cascades1.35E-074P25116, P00734, P0C0L4, P10909F2R, F2, C4A, CLUMore
Glipizidehsa04611Platelet activation1.59E-055P25116, P08514, Q15746, Q8WYR1, P07359F2R, ITGA2B, MYLK, PIK3R5, GP1BAMore
Glipizidehsa04612Antigen processing and presentation5.02E-089P13765, P48382, P01730, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, CD4, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Glipizidehsa04613Neutrophil extracellular trap formation3.33E-1124P17252, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P0C0S5, Q6FI13, Q93077, P62807, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, P63261, O43315, Q16539PRKCA, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AFZ, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, ACTG1, AQP9, MAPK14More
Glipizidehsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Glipizidehsa04620Toll-like receptor signaling pathway4.16E-022Q13546, P01568RIPK1, IFNA21More
Glipizidehsa04621NOD-like receptor signaling pathway1.30E-0516Q16539, Q14643, P01568, P25963, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, Q13546, Q05823, P01375, P09341, P49913, P12838MAPK14, ITPR1, IFNA21, NFKBIA, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, RIPK1, RNASEL, TNF, CXCL1, CAMP, DEFA4More
Glipizidehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Glipizidehsa04623Cytosolic DNA-sensing pathway2.38E-075P01584, P01568, Q13546, P25963, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, CCL4L2More
Glipizidehsa04625C-type lectin receptor signaling pathway2.95E-0410Q9ULY5, Q13153, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P0DP24, Q16539CLEC4E, PAK1, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, CALM2, MAPK14More
Glipizidehsa04630JAK-STAT signaling pathway4.43E-023P48551, P40189, Q06124IFNAR2, IL6ST, PTPN11More
Glipizidehsa04640Hematopoietic cell lineage1.68E-0817P13612, P14778, P27930, P11215, P15144, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375, P01584ITGA4, IL1R1, IL1R2, ITGAM, ANPEP, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF, IL1BMore
Glipizidehsa04650Natural killer cell mediated cytotoxicity1.47E-1214P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q13153, Q13241, P26718, O14931, O75015, P26717, P26715PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, PAK1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC1More
Glipizidehsa04657IL-17 signaling pathway1.71E-0914P25963, P08238, O00463, Q07955, Q16539, P49841, P09341, P14780, Q9UJX4, P04141, P80188, P01375, P06702, P01584NFKBIA, HSP90AB1, TRAF5, SFRS1, MAPK14, GSK3B, CXCL1, MMP9, ANAPC5, CSF2, LCN2, TNF, S100A9, IL1BMore
Glipizidehsa04658Th1 and Th2 cell differentiation1.73E-2115Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P13765, P23458, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, JAK1, RUNX3More
Glipizidehsa04659Th17 cell differentiation6.81E-1416Q04759, Q16539, P19174, P01730, P06239, P14784, P13765, P14778, Q9HBE5, Q9UL17, P23771, P01584, P07766, P09693, P20963, P23458PRKCQ, MAPK14, PLCG1, CD4, LCK, IL2RB, HLA-DOB, IL1R1, IL21R, TBX21, GATA3, IL1B, CD3E, CD3G, CD247, JAK1More
Glipizidehsa04660T cell receptor signaling pathway6.92E-1822P01375, P04141, P25963, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, Q13153, P16333, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P29350, Q16539, P49841TNF, CSF2, NFKBIA, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, PAK1, NCK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, PTPN6, MAPK14, GSK3BMore
Glipizidehsa04662B cell receptor signaling pathway1.49E-035P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Glipizidehsa04664Fc epsilon RI signaling pathway1.07E-047P01375, Q16539, P42338, Q9UQC2, P07948, P09917, P20292TNF, MAPK14, PIK3CB, GAB2, LYN, ALOX5, ALOX5APMore
Glipizidehsa04666Fc gamma R-mediated phagocytosis8.54E-047O75015, P23528, P49006, P06396, O14494, P14598, P17252FCGR3B, CFL1, MARCKSL1, GSN, PLPP1, NCF1, PRKCAMore
Glipizidehsa04668TNF signaling pathway8.87E-0513P01375, O00463, Q13489, Q16539, P25963, Q99941, P18848, P01584, P20749, Q13077, P14780, P20333, O95429TNF, TRAF5, BIRC3, MAPK14, NFKBIA, CREBL1, ATF4, IL1B, BCL3, TRAF1, MMP9, TNFRSF1B, BAG4More
Glipizidehsa04670Leukocyte transendothelial migration4.20E-027P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXKMore
Glipizidehsa04672Intestinal immune network for IgA production4.27E-022P13765, P13612HLA-DOB, ITGA4More
Glipizidehsa04710Circadian rhythm1.67E-022Q16526, Q9Y478CRY1, PRKAB1More
Glipizidehsa04713Circadian entrainment6.44E-059P0DP23, P0DP24, Q13557, Q02153, P17252, P62873, P61952, Q08828, O15055CALM1, CALM2, CAMK2D, GUCY1B3, PRKCA, GNB1, GNG11, ADCY1, PER2More
Glipizidehsa04714Thermogenesis4.80E-026P22694, Q16539, Q969G3, P33121, Q16718, O14521PRKACB, MAPK14, SMARCE1, ACSL1, NDUFA5, SDHDMore
Glipizidehsa04720Long-term potentiation2.60E-024Q13557, P0DP24, P18848, Q08828CAMK2D, CALM2, ATF4, ADCY1More
Glipizidehsa04722Neurotrophin signaling pathway3.76E-023P51617, P10415, P0DP23IRAK1, BCL2, CALM1More
Glipizidehsa04723Retrograde endocannabinoid signaling3.71E-024P62873, P61952, Q08828, O15239GNB1, GNG11, ADCY1, NDUFA1More
Glipizidehsa04724Glutamatergic synapse4.31E-069P48058, O15399, Q08828, P62873, P63218, P50151, P61952, P15104, Q9NSB8GRIA4, GRIN2D, ADCY1, GNB1, GNG5, GNG10, GNG11, GLUL, HOMER2More
Glipizidehsa04725Cholinergic synapse8.49E-0511Q08828, P22694, Q14643, P62873, P63218, P50151, P61952, P18848, Q13557, P42338, P10415ADCY1, PRKACB, ITPR1, GNB1, GNG5, GNG10, GNG11, ATF4, CAMK2D, PIK3CB, BCL2More
Glipizidehsa04727GABAergic synapse4.34E-047Q08828, P62873, P63218, P50151, P61952, P15104, Q15111ADCY1, GNB1, GNG5, GNG10, GNG11, GLUL, PLCL1More
Glipizidehsa04728Dopaminergic synapse1.62E-037P62873, P61952, Q99941, P18848, Q13557, P0DP24, O15516GNB1, GNG11, CREBL1, ATF4, CAMK2D, CALM2, CLOCKMore
Glipizidehsa04730Long-term depression2.54E-022Q14344, P07948GNA13, LYNMore
Glipizidehsa04740Olfactory transduction3.49E-044P62873, Q13557, P0DP23, P0DP24GNB1, CAMK2D, CALM1, CALM2More
Glipizidehsa04744Phototransduction3.73E-063P62873, P0DP23, P0DP24GNB1, CALM1, CALM2More
Glipizidehsa04750Inflammatory mediator regulation of TRP channels4.07E-0614P14778, P01584, Q08828, P51828, P22694, Q13557, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, CAMK2D, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2, CALM1More
Glipizidehsa04810Regulation of actin cytoskeleton1.38E-034P24844, Q15746, P08514, P25116MYL9, MYLK, ITGA2B, F2RMore
Glipizidehsa04911Insulin secretion1.06E-024Q08828, Q99941, P18848, Q13557ADCY1, CREBL1, ATF4, CAMK2DMore
Glipizidehsa04912GnRH signaling pathway6.12E-036P51828, Q16539, Q9Y6R4, Q14643, P0DP24, P22694ADCY7, MAPK14, MAP3K4, ITPR1, CALM2, PRKACBMore
Glipizidehsa04913Ovarian steroidogenesis2.72E-022P42330, P22694AKR1C3, PRKACBMore
Glipizidehsa04915Estrogen signaling pathway2.49E-0310Q99941, P18848, Q08828, P51828, P07900, P0DMV8, P11142, P0DP23, P0DP24, Q15788CREBL1, ATF4, ADCY1, ADCY7, HSP90AA1, HSPA1A, HSPA8, CALM1, CALM2, NCOA1More
Glipizidehsa04918Thyroid hormone synthesis3.71E-024Q08828, Q99941, P18848, P02768ADCY1, CREBL1, ATF4, ALBMore
Glipizidehsa04920Adipocytokine signaling pathway5.84E-036P25963, P33121, Q9Y478, Q04759, Q96RR4, P01375NFKBIA, ACSL1, PRKAB1, PRKCQ, CAMKK2, TNFMore
Glipizidehsa04921Oxytocin signaling pathway6.37E-033Q15746, P24844, Q8WYR1MYLK, MYL9, PIK3R5More
Glipizidehsa04922Glucagon signaling pathway7.57E-035P14618, P22694, P06737, Q12778, Q14643PKM2, PRKACB, PYGL, FOXO1, ITPR1More
Glipizidehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Glipizidehsa04924Renin secretion7.24E-053P22694, P07550, Q14643PRKACB, ADRB2, ITPR1More
Glipizidehsa04925Aldosterone synthesis and secretion6.67E-035Q99941, P18848, Q08828, P0DP24, Q13557CREBL1, ATF4, ADCY1, CALM2, CAMK2DMore
Glipizidehsa04926Relaxin signaling pathway3.94E-0410P42338, P62873, P63218, P50151, P61952, Q99941, P18848, P49767, Q08828, P49407PIK3CB, GNB1, GNG5, GNG10, GNG11, CREBL1, ATF4, VEGFC, ADCY1, ARRB1More
Glipizidehsa04927Cortisol synthesis and secretion2.12E-035Q14643, Q99941, P18848, Q08828, P22694ITPR1, CREBL1, ATF4, ADCY1, PRKACBMore
Glipizidehsa04928Parathyroid hormone synthesis, secretion and action1.32E-034Q14643, P22694, P23771, P10415ITPR1, PRKACB, GATA3, BCL2More
Glipizidehsa04929GnRH secretion4.62E-022P42338, P49407PIK3CB, ARRB1More
Glipizidehsa04932Non-alcoholic fatty liver disease7.69E-058O43521, P18848, O75460, P01584, P13073, P12074, O15239, O95298BCL2L11, ATF4, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFC2More
Glipizidehsa04933AGE-RAGE signaling pathway in diabetic complications1.72E-025P42224, Q12778, P49767, P17252, P19174STAT1, FOXO1, VEGFC, PRKCA, PLCG1More
Glipizidehsa04934Cushing syndrome3.10E-037Q14643, Q99941, P18848, Q08828, P22694, Q13557, P04628ITPR1, CREBL1, ATF4, ADCY1, PRKACB, CAMK2D, WNT1More
Glipizidehsa04940Type I diabetes mellitus4.18E-023P10747, P13765, P01375CD28, HLA-DOB, TNFMore
Glipizidehsa04962Vasopressin-regulated water reabsorption2.95E-043P52566, P62491, P46459ARHGDIB, RAB11A, NSFMore
Glipizidehsa04964Proximal tubule bicarbonate reclamation2.08E-043P22748, P00918, P49448CA4, CA2, GLUD2More
Glipizidehsa04966Collecting duct acid secretion2.17E-031P00918CA2More
Glipizidehsa04970Salivary secretion4.59E-0510P07550, Q08828, P51828, P22694, Q14643, P17252, P0DP23, P0DP24, Q02153, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, PRKCA, CALM1, CALM2, GUCY1B3, CAMPMore
Glipizidehsa04972Pancreatic secretion1.99E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Glipizidehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Glipizidehsa04975Fat digestion and absorption1.43E-031O14494PLPP1More
Glipizidehsa04976Bile secretion4.78E-023Q08828, P51828, Q14032ADCY1, ADCY7, BAATMore
Glipizidehsa05010Alzheimer disease2.21E-0210O15239, P13073, P12074, Q00535, O75460, P0DP23, P01584, O95197, P67870, P28070NDUFA1, COX4I1, COX6A1, CDK5, ERN1, CALM1, IL1B, RTN3, CSNK2B, PSMB4More
Glipizidehsa05012Parkinson disease3.39E-0314O15239, Q16718, O14521, P13073, P12074, P05496, P05141, P18848, P19174, P0DP23, P0DP24, Q13557, Q13509, P68371NDUFA1, NDUFA5, SDHD, COX4I1, COX6A1, ATP5G1, SLC25A5, ATF4, PLCG1, CALM1, CALM2, CAMK2D, TUBB3, TUBB2CMore
Glipizidehsa05016Huntington disease1.00E-0412O95298, P13073, P12074, Q9GZM3, P24928, P30876, P62487, P52435, Q9NYC9, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2J2, POLR2A, POLR2B, POLR2G, POLR2J, DNAH9, ERN1, PSMB4, PSMD12More
Glipizidehsa05020Prion disease1.86E-0210P01584, P46531, P11142, O15239, P05496, P13073, P12074, P18848, P05141, Q99941IL1B, NOTCH1, HSPA8, NDUFA1, ATP5G1, COX4I1, COX6A1, ATF4, SLC25A5, CREBL1More
Glipizidehsa05022Pathways of neurodegeneration - multiple diseases2.29E-029Q13509, P68371, Q16718, O14521, Q13561, P19174, P17252, Q08752, P0DP23TUBB3, TUBB2C, NDUFA5, SDHD, DCTN2, PLCG1, PRKCA, PPID, CALM1More
Glipizidehsa05031Amphetamine addiction1.06E-024P0DP24, Q13557, Q99941, P18848CALM2, CAMK2D, CREBL1, ATF4More
Glipizidehsa05033Nicotine addiction2.54E-022P28472, O15399GABRB3, GRIN2DMore
Glipizidehsa05034Alcoholism1.90E-0512Q99941, P18848, P0DP24, Q96RR4, P62873, P61952, P0C0S5, Q93077, P62807, O60814, P84243, P68431CREBL1, ATF4, CALM2, CAMKK2, GNB1, GNG11, H2AFZ, HIST1H2AC, HIST1H2BC, H2BC12, H3F3A, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Glipizidehsa05100Bacterial invasion of epithelial cells4.50E-021Q92529SHC3More
Glipizidehsa05110Vibrio cholerae infection2.98E-055Q13488, Q99437, P17252, P19174, P60709TCIRG1, ATP6V0B, PRKCA, PLCG1, ACTBMore
Glipizidehsa05120Epithelial cell signaling in Helicobacter pylori infection2.27E-057Q16539, Q13153, P09341, P19875, P19174, P25024, P25025MAPK14, PAK1, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Glipizidehsa05130Pathogenic Escherichia coli infection2.51E-023Q14247, O00501, P25116CTTN, CLDN5, F2RMore
Glipizidehsa05131Shigellosis3.34E-0211P01375, P25963, O00463, Q04759, Q9UDY8, Q9H1Y0, Q14643, Q12778, Q13315, P10415, Q96A32TNF, NFKBIA, TRAF5, PRKCQ, MALT1, ATG5, ITPR1, FOXO1, ATM, BCL2, MYLPFMore
Glipizidehsa05132Salmonella infection3.10E-0719P51617, P25963, P01375, P08238, Q9UJU2, P63261, Q13546, Q13489, P10415, P04406, O75369, Q96A32, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371, P49754IRAK1, NFKBIA, TNF, HSP90AB1, LEF1, ACTG1, RIPK1, BIRC3, BCL2, GAPDH, FLNB, MYLPF, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2C, VPS41More
Glipizidehsa05133Pertussis2.60E-042P0DP23, P0C0L4CALM1, C4AMore
Glipizidehsa05134Legionellosis6.26E-058P01584, Q9NR31, P11215, P68104, P0DMV8, P11142, P09341, P19875IL1B, SAR1A, ITGAM, EEF1A1, HSPA1A, HSPA8, CXCL1, CXCL2More
Glipizidehsa05140Leishmaniasis5.60E-1115P13612, O75015, P14598, P23458, P42224, P13765, O60603, P25963, P01375, P01584, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Glipizidehsa05143African trypanosomiasis1.74E-032P69905, P68871HBA2, HBBMore
Glipizidehsa05144Malaria8.68E-068P60033, P69905, P68871, O60603, P01375, P35443, P01584, P26718CD81, HBA2, HBB, TLR2, TNF, THBS4, IL1B, KLRK1More
Glipizidehsa05145Toxoplasmosis3.07E-027P51617, P25963, P01375, P10415, Q13489, P13765, O60603IRAK1, NFKBIA, TNF, BCL2, BIRC3, HLA-DOB, TLR2More
Glipizidehsa05146Amoebiasis6.34E-1013P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSGMore
Glipizidehsa05150Staphylococcus aureus infection2.37E-049P0C0L4, P21730, P21462, O75015, P13765, Q16581, P13646, P12838, P49913C4A, C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, KRT13, DEFA4, CAMPMore
Glipizidehsa05152Tuberculosis1.62E-0513Q13488, Q99437, P0DP23, O75015, P48382, O60603, P01375, P10415, P13765, P25774, P49913, Q9UDY8, P51617TCIRG1, ATP6V0B, CALM1, FCGR3B, RFX5, TLR2, TNF, BCL2, HLA-DOB, CTSS, CAMP, MALT1, IRAK1More
Glipizidehsa05161Hepatitis B2.33E-028P17252, P14780, P25963, P01375, P10415, P51617, O60603, Q14765PRKCA, MMP9, NFKBIA, TNF, BCL2, IRAK1, TLR2, STAT4More
Glipizidehsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Glipizidehsa05163Human cytomegalovirus infection2.68E-0622P01375, P62873, P61952, Q14643, P0DP23, P0DP24, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, P61073, Q13651, P25025, Q16539, Q99941, P18848, P04637, O00463, P61769TNF, GNB1, GNG11, ITPR1, CALM1, CALM2, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, CXCR4, IL10RA, CXCR2, MAPK14, CREBL1, ATF4, TP53, TRAF5, B2MMore
Glipizidehsa05167Kaposi sarcoma-associated herpesvirus infection5.71E-038P01568, P42224, P25963, P40189, P62873, P19174, P04141, P0DP23IFNA21, STAT1, NFKBIA, IL6ST, GNB1, PLCG1, CSF2, CALM1More
Glipizidehsa05168Herpes simplex virus 1 infection4.15E-0312P25963, P01568, Q9GZY0, P42224, Q07955, Q01130, Q13243, Q13398, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, NXF2; NXF2B, STAT1, SFRS1, SFRS2, SFRS5, ZNF211, ZNF85, ZNF140, ZNF189, ZNF212More
Glipizidehsa05169Epstein-Barr virus infection1.10E-0516P20023, P13765, P01106, Q13547, Q92769, O00463, Q16539, P42338, P07948, Q13761, P24522, O75293, O60603, P07766, P09693, P20963CR2, HLA-DOB, MYC, HDAC1, HDAC2, TRAF5, MAPK14, PIK3CB, LYN, RUNX3, GADD45A, GADD45B, TLR2, CD3E, CD3G, CD247More
Glipizidehsa05170Human immunodeficiency virus 1 infection9.56E-0515P62873, P0DP23, P01375, P17252, O00463, Q14643, P51617, P25963, O60603, Q13315, O95067, P10415, Q13619, Q93034, Q9Y6Q5GNB1, CALM1, TNF, PRKCA, TRAF5, ITPR1, IRAK1, NFKBIA, TLR2, ATM, CCNB2, BCL2, CUL4A, CUL5, AP1M2More
Glipizidehsa05171Coronavirus disease - COVID-191.36E-027P25963, P42224, P01568, P40189, P04141, P19174, P17252NFKBIA, STAT1, IFNA21, IL6ST, CSF2, PLCG1, PRKCAMore
Glipizidehsa05200Pathways in cancer2.92E-0318P08238, P42224, P25963, P19174, Q9UJU2, P17252, P43246, P14923, P10415, Q13077, P49767, Q12778, P62873, Q9UM47, O75293, P0DP23, P01568, P40189HSP90AB1, STAT1, NFKBIA, PLCG1, LEF1, PRKCA, MSH2, JUP, BCL2, TRAF1, VEGFC, FOXO1, GNB1, NOTCH3, GADD45B, CALM1, IFNA21, IL6STMore
Glipizidehsa05202Transcriptional misregulation in cancer2.74E-1324Q12778, Q15532, Q13315, P41732, P17844, P14780, P27930, P14923, Q15744, Q16548, Q13489, Q13077, O15550, P04637, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, SS18, ATM, TSPAN7, DDX5, MMP9, IL1R2, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, UTX, TP53, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Glipizidehsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Glipizidehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Glipizidehsa05205Proteoglycans in cancer3.72E-0311Q13009, Q12955, Q14643, O75369, P63261, P04637, P14780, P17252, O60603, Q13635, P08962TIAM1, ANK3, ITPR1, FLNB, ACTG1, TP53, MMP9, PRKCA, TLR2, PTCH1, CD63More
Glipizidehsa05211Renal cell carcinoma2.42E-021Q13153PAK1More
Glipizidehsa05214Glioma1.09E-024P0DP23, P17252, P19174, O75293CALM1, PRKCA, PLCG1, GADD45BMore
Glipizidehsa05216Thyroid cancer3.59E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Glipizidehsa05217Basal cell carcinoma1.61E-055Q13635, P49841, Q9UJU2, P04637, P24522PTCH1, GSK3B, LEF1, TP53, GADD45AMore
Glipizidehsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Glipizidehsa05222Small cell lung cancer2.79E-026Q13489, P10415, P25963, Q13077, O00463, P24522BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45AMore
Glipizidehsa05223Non-small cell lung cancer3.99E-024P17252, O43524, P19174, O75293PRKCA, FOXO3, PLCG1, GADD45BMore
Glipizidehsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Glipizidehsa05231Choline metabolism in cancer2.42E-057Q9NRA1, Q9Y259, P19174, P23743, P49619, O14494, P17252PDGFC, CHKB, PLCG1, DGKA, DGKG, PLPP1, PRKCAMore
Glipizidehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.76E-0916P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P29350, P23458, P42224, O60603, P10747, Q04759, Q16539, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PTPN6, JAK1, STAT1, TLR2, CD28, PRKCQ, MAPK14, CD4More
Glipizidehsa05310Asthma1.83E-063P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Glipizidehsa05321Inflammatory bowel disease1.99E-148O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1B, IL21RMore
Glipizidehsa05322Systemic lupus erythematosus3.66E-0615O75015, P08246, P08311, P09871, P01375, P10747, P13765, Q6FI13, Q93077, P62807, Q16778, O60814, P68431, P12814, P05455FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1, SSBMore
Glipizidehsa05323Rheumatoid arthritis1.45E-034P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Glipizidehsa05332Graft-versus-host disease1.08E-105P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Glipizidehsa05340Primary immunodeficiency2.19E-024P01730, P01732, P07766, P06239CD4, CD8A, CD3E, LCKMore
Glipizidehsa05412Arrhythmogenic right ventricular cardiomyopathy2.17E-031P54284CACNB3More
Glipizidehsa05414Dilated cardiomyopathy4.55E-022P54284, P26678CACNB3, PLNMore
Glipizidehsa05415Diabetic cardiomyopathy1.48E-036P17252, P14598, Q15080, Q16718, O14521, P04406PRKCA, NCF1, NCF4, NDUFA5, SDHD, GAPDHMore
Glipizidehsa05416Viral myocarditis2.30E-022P10747, P63261CD28, ACTG1More
Glipizidehsa05418Fluid shear stress and atherosclerosis2.22E-0512Q16539, Q14145, P14598, P10599, P14780, P01375, P63261, P04637, P10415, P14778, P27930, Q92974MAPK14, KEAP1, NCF1, TXN, MMP9, TNF, ACTG1, TP53, BCL2, IL1R1, IL1R2, ARHGEF2More

Community members of Glipizide (SDC: 9.54)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P62942FKBP1APeptidylNoneprolyl cisNonetrans isomerase FKBP1APredicted10.4320.269500.7551
P07384CAPN1CalpainNone1 catalytic subunitPredicted00.0230.14890.60380.9131
P21462FPR1fMetNoneLeuNonePhe receptorPredicted00.12050.34920.43781.1964
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P25774CTSSCathepsin SPredicted00.31850.49320.51681.6625
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P22001KCNA3Potassium voltageNonegated channel subfamily A member 3Predicted10.13960.505501.0809
Q13093PLA2G7PlateletNoneactivating factor acetylhydrolasePredicted00.05050.20960.15580.6001
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
Q13370PDE3BcGMPNoneinhibited 3',5'Nonecyclic phosphodiesterase BPredicted00.09060.16140.35580.7239
P14780MMP9Matrix metalloproteinaseNone9Predicted10.16960.84240.73152.5012
P07195LDHBLNonelactate dehydrogenase B chainPredicted00.01670.17490.2310.5892
P07947YES1TyrosineNoneprotein kinase YesPredicted00.12120.43450.1651.0947
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
P22894MMP8Neutrophil collagenasePredicted10.10610.35700.767
P13612ITGA4Integrin alphaNone4Predicted00.11650.23860.68621.2217
P21453S1PR1Sphingosine 1Nonephosphate receptor 1Predicted10.14340.38470.2211.0621
P42330AKR1C3AldoNoneketo reductase family 1 member C3Predicted00.40170.83480.17482.0453
Q15078CDK5R1CyclinNonedependent kinase 5 activator 1Predicted00.13580.50040.25751.3263
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
P51617IRAK1InterleukinNone1 receptorNoneassociated kinase 1Predicted00.02380.30.94441.5563
Q13153PAK1Serine/threonineNoneprotein kinase PAK 1Predicted10.46470.34710.78191.7084
O15294OGTUDPNoneNNoneacetylglucosamineNoneNonepeptide NNoneacetylglucosaminyltransferase 110 kDa subunitPredicted00.27390.06020.10210.3594
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P05186ALPLAlkaline phosphatase, tissueNonenonspecific isozymePredicted00.30640.41430.19921.181
P08514ITGA2BIntegrin alphaNoneIIbPredicted10.07820.32480.7791.4677
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
Q13557CAMK2DCalcium/calmodulinNonedependent protein kinase type II subunit deltaPredicted00.47780.3060.80951.6604
Q16548BCL2A1BclNone2Nonerelated protein A1Predicted00.03060.03360.46870.5512
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
P08311CTSGCathepsin GPredicted00.49490.18740.64781.2701
Q9GZT9EGLN1Egl nine homolog 1Predicted00.58040.60610.25561.7581
P29350PTPN6TyrosineNoneprotein phosphatase nonNonereceptor type 6Predicted10.28070.24590.56831.2004
P22748CA4Carbonic anhydrase 4Predicted00.00560.82670.16091.8171
P20292ALOX5APArachidonate 5NonelipoxygenaseNoneactivating proteinPredicted00.13030.24180.09070.6395
P00734F2ProthrombinPredicted10.09630.7070.49771.9598
Q9H5J4ELOVL6Elongation of very long chain fatty acids protein 6Predicted00.07880.03270.16660.2713
P10826RARBRetinoic acid receptor betaPredicted00.00940.34660.30050.9983
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)