PharmaCoNets of Clevidipine (SPCN: 5.11 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Clevidipinehsa00500Starch and sucrose metabolism3.88E-023O43451, P46976, P06737MGAM, GYG1, PYGLMore
Clevidipinehsa00730Thiamine metabolism3.79E-022P05186, P24666ALPL, ACP1More
Clevidipinehsa04064NF-kappa B signaling pathway1.86E-0313P10415, Q13489, O00463, Q13546, P01375, Q04759, Q9UDY8, Q13077, Q16548, Q8WV28, P24522, P09341, Q9UNE0BCL2, BIRC3, TRAF5, RIPK1, TNF, PRKCQ, MALT1, TRAF1, BCL2A1, BLNK, GADD45A, CXCL1, EDARMore
Clevidipinehsa04071Sphingolipid signaling pathway2.06E-027Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Clevidipinehsa04080Neuroactive ligand-receptor interaction2.54E-027P08311, Q15722, Q9H228, P21462, P21730, Q16581, P35318CTSG, LTB4R, EDG8, FPR1, C5AR1, C3AR1, ADMMore
Clevidipinehsa04211Longevity regulating pathway1.18E-023Q12778, Q9UEF7, Q96KQ7FOXO1, KL, EHMT2More
Clevidipinehsa04217Necroptosis2.93E-023P01568, Q13489, Q13546IFNA21, BIRC3, RIPK1More
Clevidipinehsa04340Hedgehog signaling pathway1.43E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Clevidipinehsa04613Neutrophil extracellular trap formation1.37E-0212O60603, P05164, P08246, Q9UM07, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Clevidipinehsa04620Toll-like receptor signaling pathway4.16E-022Q13546, P01568RIPK1, IFNA21More
Clevidipinehsa04621NOD-like receptor signaling pathway7.00E-0313Q16539, Q14643, P01568, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, Q13546, P01375, P09341, P12838MAPK14, ITPR1, IFNA21, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, RIPK1, TNF, CXCL1, DEFA4More
Clevidipinehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Clevidipinehsa04623Cytosolic DNA-sensing pathway2.20E-032P01568, Q13546IFNA21, RIPK1More
Clevidipinehsa04657IL-17 signaling pathway1.28E-027O00463, Q16539, P49841, P09341, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNFMore
Clevidipinehsa04658Th1 and Th2 cell differentiation3.21E-039Q04759, P20963, P09693, Q16539, Q14765, P42226, P23771, Q9UL17, P13765PRKCQ, CD247, CD3G, MAPK14, STAT4, STAT6, GATA3, TBX21, HLA-DOBMore
Clevidipinehsa04659Th17 cell differentiation3.18E-028Q04759, Q16539, P42226, P13765, Q9UL17, P23771, P09693, P20963PRKCQ, MAPK14, STAT6, HLA-DOB, TBX21, GATA3, CD3G, CD247More
Clevidipinehsa04660T cell receptor signaling pathway1.07E-029P01375, Q04759, O95267, Q08881, P20963, P09693, P01732, Q16539, P49841TNF, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, MAPK14, GSK3BMore
Clevidipinehsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Clevidipinehsa05132Salmonella infection9.85E-034Q13546, Q13489, O60282, P68371RIPK1, BIRC3, KIF5C, TUBB2CMore
Clevidipinehsa05150Staphylococcus aureus infection4.37E-026P21730, P21462, O75015, P13765, Q16581, P12838C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, DEFA4More
Clevidipinehsa05169Epstein-Barr virus infection4.32E-0211P13765, O00463, P16070, P10415, Q16539, P24522, Q8WV28, P01375, O60603, P09693, P20963HLA-DOB, TRAF5, CD44, BCL2, MAPK14, GADD45A, BLNK, TNF, TLR2, CD3G, CD247More
Clevidipinehsa05202Transcriptional misregulation in cancer8.07E-0414Q15532, P14780, P27930, Q16548, Q13077, Q15652, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, P24522SS18, MMP9, IL1R2, BCL2A1, TRAF1, JMJD1C, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, GADD45AMore
Clevidipinehsa05217Basal cell carcinoma1.43E-024Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Clevidipinehsa05321Inflammatory bowel disease7.62E-047O60603, P01375, P13765, Q14765, Q9UL17, P42226, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, STAT6, GATA3More

Community members of Clevidipine (SDC: 1.79)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P06737PYGLGlycogen phosphorylase, liver formPredicted00.37330.22110.31690.9457
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)