PharmaCoNets of Cilostazol (SPCN: 230.77 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Cilostazolhsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Cilostazolhsa00030Pentose phosphate pathway2.51E-044P60891, P51854, P08237, P37837PRPS1, TKTL1, PFKM, TALDO1More
Cilostazolhsa00040Pentose and glucuronate interconversions6.04E-043P15121, O60701, P14550AKR1B1, UGDH, AKR1A1More
Cilostazolhsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Cilostazolhsa00071Fatty acid degradation3.50E-024O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Cilostazolhsa00190Oxidative phosphorylation9.96E-053Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Cilostazolhsa00220Arginine biosynthesis1.26E-033P15104, P05089, P49448GLUL, ARG1, GLUD2More
Cilostazolhsa00250Alanine, aspartate and glutamate metabolism2.42E-021P15104GLULMore
Cilostazolhsa00310Lysine degradation2.60E-033Q8NEZ4, Q13029, Q02809MLL3, PRDM2, PLOD1More
Cilostazolhsa00500Starch and sucrose metabolism9.82E-063O43451, P46976, P06737MGAM, GYG1, PYGLMore
Cilostazolhsa00510N-Glycan biosynthesis3.15E-022P15907, Q9NR34ST6GAL1, MAN1C1More
Cilostazolhsa00512Mucin type O-glycan biosynthesis3.78E-022O95395, Q8N4A0GCNT3, GALNT4More
Cilostazolhsa00520Amino sugar and nucleotide sugar metabolism5.54E-043Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Cilostazolhsa00533Glycosaminoglycan biosynthesis - keratan sulfate3.43E-021Q9NY97B3GNT2More
Cilostazolhsa00561Glycerolipid metabolism7.94E-033P15121, P14550, Q86XP1AKR1B1, AKR1A1, DGKHMore
Cilostazolhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Cilostazolhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Cilostazolhsa00600Sphingolipid metabolism2.65E-033Q9BX95, Q06136, P15289SGPP1, FVT1, ARSAMore
Cilostazolhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series4.91E-052P06865, O75752HEXA, B3GALNT1More
Cilostazolhsa00630Glyoxylate and dicarboxylate metabolism2.27E-052P40925, P15104MDH1, GLULMore
Cilostazolhsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Cilostazolhsa00730Thiamine metabolism1.55E-032P05186, P24666ALPL, ACP1More
Cilostazolhsa00740Riboflavin metabolism4.77E-021P30043BLVRBMore
Cilostazolhsa00785Lipoic acid metabolism4.32E-021Q9Y234LIPT1More
Cilostazolhsa00830Retinol metabolism2.27E-035P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Cilostazolhsa00860Porphyrin and chlorophyll metabolism4.14E-021P53004BLVRAMore
Cilostazolhsa00910Nitrogen metabolism2.42E-021P15104GLULMore
Cilostazolhsa00970Aminoacyl-tRNA biosynthesis2.41E-054O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Cilostazolhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Cilostazolhsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Cilostazolhsa00983Drug metabolism - other enzymes3.32E-023P04183, P32320, P05164TK1, CDA, MPOMore
Cilostazolhsa01100Metabolic pathways1.78E-0348Q9NR34, Q9Y234, P35790, P05089, Q16772, P15144, P30041, O14732, P32320, Q02153, Q16774, P20839, P00918, P22748, P10768, P55809, P06280, Q16875, O43286, O43451, Q9Y6K0, P05186, P24666, P08237, P21399, Q9HCC0, P33121, Q9UHK6, P51854, Q86VZ5, Q9BVK2, P15907, P57054, Q9UNP4, O96024, Q9BX95, P37837, P32321, P50213, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q969G6, Q13029, Q9NVH6MAN1C1, LIPT1, CHKA, ARG1, GSTA3, ANPEP, PRDX6, IMPA2, CDA, GUCY1B3, GUK1, IMPDH1, CA2, CA4, ESD, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, CEPT1, ALPL, ACP1, PFKM, ACO1, MCCC2, ACSL1, AMACR, TKTL1, SGMS1, ALG8, ST6GAL1, PIGP, ST3GAL5, B3GALT4, SGPP1, TALDO1, DCTD, IDH3A, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, RFK, PRDM2, TMLHEMore
Cilostazolhsa01200Carbon metabolism1.81E-026P51854, P08237, P37837, P50213, P21399, P10768TKTL1, PFKM, TALDO1, IDH3A, ACO1, ESDMore
Cilostazolhsa012102-Oxocarboxylic acid metabolism1.73E-022P21399, P50213ACO1, IDH3AMore
Cilostazolhsa01230Biosynthesis of amino acids7.61E-069P08237, P51854, P60891, Q99707, P21399, P50213, P05089, P15104, P37837PFKM, TKTL1, PRPS1, MTR, ACO1, IDH3A, ARG1, GLUL, TALDO1More
Cilostazolhsa01240Biosynthesis of cofactors2.05E-022P36551, O60701CPOX, UGDHMore
Cilostazolhsa01522Endocrine resistance4.55E-025P14780, P22694, Q9UM47, P10415, Q13323MMP9, PRKACB, NOTCH3, BCL2, BIKMore
Cilostazolhsa01523Antifolate resistance1.02E-055P41440, Q92820, P04818, P01375, P18054SLC19A1, GGH, TYMS, TNF, ALOX12More
Cilostazolhsa03010Ribosome1.60E-029P30050, P40429, P62906, P62917, Q9H0U6, P36578, P05386, P62249, P23396RPL12, RPL13A, RPL10A, RPL8, MRPL18, RPL4, RPLP1, RPS16, RPS3More
Cilostazolhsa03013RNA transport1.05E-0413P62826, O14893, P38919, Q9UBU9, P37198, P35658, P63279, P68104, P55884, Q14240, Q9BZI7, Q14232, Q06787RAN, GEMIN2, EIF4A3, NXF1, NUP62, NUP214, UBE2I, EEF1A1, EIF3B, EIF4A2, UPF3B, EIF2B1, FMR1More
Cilostazolhsa03015mRNA surveillance pathway4.81E-022Q9BZI7, O94913UPF3B, PCF11More
Cilostazolhsa03020RNA polymerase6.63E-054P30876, P24928, P62487, Q9Y535POLR2B, POLR2A, POLR2G, POLR3HMore
Cilostazolhsa03030DNA replication1.48E-023P49005, P33993, P15927POLD2, MCM7, RPA2More
Cilostazolhsa03040Spliceosome7.21E-0916Q14562, O43143, O60508, P08579, P26368, O75940, O75494, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, SMNDC1, FUSIP1, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Cilostazolhsa03050Proteasome4.83E-021P55036PSMD4More
Cilostazolhsa03060Protein export4.42E-022P37108, Q15005SRP14, SPCS2More
Cilostazolhsa03320PPAR signaling pathway4.55E-022O00767, Q02318SCD, CYP27A1More
Cilostazolhsa03430Mismatch repair4.38E-021P20585MSH3More
Cilostazolhsa03450Non-homologous end-joining3.17E-032Q9NP87, P13010POLM, XRCC5More
Cilostazolhsa04014Ras signaling pathway1.30E-0312P42338, P20827, Q9NRA1, P49767, Q13009, P17252, Q7LDG7, P0DP23, P62873, P63218, P50151, P19174PIK3CB, EFNA1, PDGFC, VEGFC, TIAM1, PRKCA, RASGRP2, CALM1, GNB1, GNG5, GNG10, PLCG1More
Cilostazolhsa04015Rap1 signaling pathway4.21E-0413P20827, Q9NRA1, P49767, P06213, Q96FS4, P11215, Q13009, O00522, Q7LDG7, P42338, P0DP23, P17252, P19174EFNA1, PDGFC, VEGFC, INSR, SIPA1, ITGAM, TIAM1, KRIT1, RASGRP2, PIK3CB, CALM1, PRKCA, PLCG1More
Cilostazolhsa04020Calcium signaling pathway9.09E-0615Q96DU7, Q08828, Q13557, P17252, P21860, P19174, P0DP23, P05141, P12236, P51828, P26678, P63092, P20020, Q9NRA1, P49767ITPKC, ADCY1, CAMK2D, PRKCA, ERBB3, PLCG1, CALM1, SLC25A5, SLC25A6, ADCY7, PLN, GNAS, ATP2B1, PDGFC, VEGFCMore
Cilostazolhsa04022cGMP-PKG signaling pathway1.26E-0410P61586, P26678, Q99941, P18848, P31751, Q08828, P51828, P05141, P12236, P0DP23RHOA, PLN, CREBL1, ATF4, AKT2, ADCY1, ADCY7, SLC25A5, SLC25A6, CALM1More
Cilostazolhsa04024cAMP signaling pathway4.63E-037Q08828, P51828, P42338, P31751, P0DP23, Q13370, Q13009ADCY1, ADCY7, PIK3CB, AKT2, CALM1, PDE3B, TIAM1More
Cilostazolhsa04060Cytokine-cytokine receptor interaction8.46E-0414P14784, P27930, P14778, P37173, P26842, Q06643, Q13651, P78552, P25024, Q9UBD3, P47992, P09341, P80075, P01730IL2RB, IL1R2, IL1R1, TGFBR2, CD27, LTB, IL10RA, IL13RA1, CXCR1, XCL2, XCL1, CXCL1, CCL8, CD4More
Cilostazolhsa04061Viral protein interaction with cytokine and cytokine receptor1.72E-0510Q8NHW4, P09341, P25024, P02775, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCR1, PPBP, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Cilostazolhsa04062Chemokine signaling pathway2.28E-0415P25024, P09341, P47992, Q9UBD3, P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q08881, Q7LDG7, Q13009, Q8WYR1CXCR1, CXCL1, XCL1, XCL2, FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, ITK, RASGRP2, TIAM1, PIK3R5More
Cilostazolhsa04064NF-kappa B signaling pathway3.22E-1323P10415, Q13489, P51617, O00463, Q13546, P14778, P01584, P01375, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, Q06643, Q9UNE0, Q9NQC7BCL2, BIRC3, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, LTB, EDAR, CYLDMore
Cilostazolhsa04070Phosphatidylinositol signaling system1.73E-0511P19174, P0DP23, P42338, O14986, P23743, Q86XP1, Q16760, P48426, P27987, Q96DU7, P17252PLCG1, CALM1, PIK3CB, PIP5K1B, DGKA, DGKH, DGKD, PIP4K2A, ITPKB, ITPKC, PRKCAMore
Cilostazolhsa04071Sphingolipid signaling pathway7.71E-068P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Cilostazolhsa04072Phospholipase D signaling pathway2.40E-036P31751, O14986, Q15438, Q08828, P51828, Q16760AKT2, PIP5K1B, PSCD1, ADCY1, ADCY7, DGKDMore
Cilostazolhsa04080Neuroactive ligand-receptor interaction1.88E-0311P08311, Q15722, P21453, Q9H228, P43657, O00398, P21462, P21730, Q16581, P14416, P35318CTSG, LTB4R, S1PR1, EDG8, P2RY5, P2RY10, FPR1, C5AR1, C3AR1, DRD2, ADMMore
Cilostazolhsa04110Cell cycle1.97E-057P06493, O60566, O75293, P30304, P33981, P42773, P01106CDK1, BUB1B, GADD45B, CDC25A, TTK, CDKN2C, MYCMore
Cilostazolhsa04114Oocyte meiosis9.42E-0710Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5DMore
Cilostazolhsa04120Ubiquitin mediated proteolysis4.82E-032Q9UBT2, Q14669SAE2, TRIP12More
Cilostazolhsa04140Autophagy - animal9.12E-0410P31751, Q7L523, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9AKT2, RRAGA, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Cilostazolhsa04142Lysosome2.45E-039Q99437, P25774, P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916ATP6V0B, CTSS, HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2More
Cilostazolhsa04144Endocytosis1.67E-028P0DMV8, Q9H444, O75351, P62491, Q96B97, Q15438, Q14161, Q9UMY4HSPA1A, CHMP4B, VPS4B, RAB11A, SH3KBP1, PSCD1, GIT2, SNX12More
Cilostazolhsa04145Phagosome1.50E-0513O75015, Q15080, P14598, Q13509, P68371, Q13488, Q99437, P05164, P78380, O60603, P35443, P13765, P25774FCGR3B, NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, ATP6V0B, MPO, OLR1, TLR2, THBS4, HLA-DOB, CTSSMore
Cilostazolhsa04150mTOR signaling pathway3.60E-023Q02750, Q9NQL2, P51812MAP2K1, RRAGD, RPS6KA3More
Cilostazolhsa04151PI3K-Akt signaling pathway3.50E-0424P42338, P21860, P43657, P27348, P20827, O14944, P49767, P07900, P08238, Q15831, Q8WYR1, P63218, P50151, O15335, P02452, P24821, Q13751, P22105, P14784, P01568, Q99941, P18848, P30281, O95988PIK3CB, ERBB3, P2RY5, YWHAQ, EFNA1, EREG, VEGFC, HSP90AA1, HSP90AB1, STK11, PIK3R5, GNG5, GNG10, CHAD, COL1A1, TNC, LAMB3, TNXB, IL2RB, IFNA21, CREBL1, ATF4, CCND3, TCL1BMore
Cilostazolhsa04211Longevity regulating pathway9.34E-047Q12778, P31751, Q08828, P51828, P18848, Q9UEF7, Q96KQ7FOXO1, AKT2, ADCY1, ADCY7, ATF4, KL, EHMT2More
Cilostazolhsa04213Longevity regulating pathway - multiple species3.11E-034P31751, Q08828, P51828, P0DMV8AKT2, ADCY1, ADCY7, HSPA1AMore
Cilostazolhsa04215Apoptosis - multiple species1.56E-022Q13489, P10415BIRC3, BCL2More
Cilostazolhsa04217Necroptosis1.73E-059P01568, Q13489, Q13546, P42224, P08238, Q6FI13, Q93077, O43633, Q08752IFNA21, BIRC3, RIPK1, STAT1, HSP90AB1, H2AC18; H2AC19, HIST1H2AC, CHMP2A, PPIDMore
Cilostazolhsa04218Cellular senescence4.79E-024P01106, O75293, P30304, P06493MYC, GADD45B, CDC25A, CDK1More
Cilostazolhsa04261Adrenergic signaling in cardiomyocytes7.19E-0511P63092, Q08828, P51828, P31751, Q99941, P18848, P26678, Q13362, Q14738, P0DP23, Q13557GNAS, ADCY1, ADCY7, AKT2, CREBL1, ATF4, PLN, PPP2R5C, PPP2R5D, CALM1, CAMK2DMore
Cilostazolhsa04270Vascular smooth muscle contraction6.96E-036P0DP23, Q08828, P51828, P35579, P35749, P35318CALM1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Cilostazolhsa04330Notch signaling pathway2.24E-044Q92542, P49768, Q92830, P78504NCSTN, PSEN1, KAT2A, JAG1More
Cilostazolhsa04340Hedgehog signaling pathway3.46E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Cilostazolhsa04360Axon guidance1.96E-048P16333, P20827, O95631, P17252, P42338, P07332, P23528, P19174NCK1, EFNA1, NTN1, PRKCA, PIK3CB, FES, CFL1, PLCG1More
Cilostazolhsa04370VEGF signaling pathway7.99E-073P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Cilostazolhsa04371Apelin signaling pathway1.11E-0311P63218, P50151, Q8WYR1, P31751, Q08828, P51828, Q14814, Q14344, Q13485, P84022, P0DP23GNG5, GNG10, PIK3R5, AKT2, ADCY1, ADCY7, MEF2D, GNA13, SMAD4, SMAD3, CALM1More
Cilostazolhsa04380Osteoclast differentiation5.22E-0614Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P31751, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, AKT2, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Cilostazolhsa04390Hippo signaling pathway2.43E-056P84022, Q13485, P04628, Q9UJU2, O43623, Q13489SMAD3, SMAD4, WNT1, LEF1, SNAI2, BIRC3More
Cilostazolhsa04512ECM-receptor interaction7.53E-032P02452, P24821COL1A1, TNCMore
Cilostazolhsa04530Tight junction2.45E-036Q8TEU7, P16989, P56750, O00501, Q14247, P24844RAPGEF6, CSDA, CLDN17, CLDN5, CTTN, MYL9More
Cilostazolhsa04540Gap junction1.67E-024P17252, Q13509, P68371, Q9NRA1PRKCA, TUBB3, TUBB2C, PDGFCMore
Cilostazolhsa04610Complement and coagulation cascades2.46E-023P00734, P0C0L4, P21730F2, C4A, C5AR1More
Cilostazolhsa04612Antigen processing and presentation6.35E-079P13765, P48382, P01730, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, CD4, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Cilostazolhsa04613Neutrophil extracellular trap formation1.75E-0823P17252, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P0C0S5, Q6FI13, Q93077, P62807, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539PRKCA, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AFZ, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Cilostazolhsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Cilostazolhsa04620Toll-like receptor signaling pathway2.23E-055Q13546, P01568, P01584, P31751, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, CCL4L2More
Cilostazolhsa04621NOD-like receptor signaling pathway7.15E-0415Q16539, Q14643, P01568, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, Q13546, P29728, Q05823, P01375, P09341, P12838MAPK14, ITPR1, IFNA21, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, RIPK1, OAS2, RNASEL, TNF, CXCL1, DEFA4More
Cilostazolhsa04622RIG-I-like receptor signaling pathway3.99E-042P01568, Q13546IFNA21, RIPK1More
Cilostazolhsa04623Cytosolic DNA-sensing pathway1.43E-136P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Cilostazolhsa04625C-type lectin receptor signaling pathway4.13E-0511Q9ULY5, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P31751, P0DP24, P0DP23, Q16539CLEC4E, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, AKT2, CALM2, CALM1, MAPK14More
Cilostazolhsa04630JAK-STAT signaling pathway4.54E-023P31751, P23458, Q13651AKT2, JAK1, IL10RAMore
Cilostazolhsa04640Hematopoietic cell lineage9.20E-0816P13612, P21926, P14778, P27930, P15144, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375, P01584ITGA4, CD9, IL1R1, IL1R2, ANPEP, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF, IL1BMore
Cilostazolhsa04650Natural killer cell mediated cytotoxicity1.42E-0914P16298, P50591, P01375, P78314, P06239, O60880, P20963, Q02750, Q13241, P26718, O14931, O75015, P26717, P26715PPP3CB, TNFSF10, TNF, SH3BP2, LCK, SH2D1A, CD247, MAP2K1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC1More
Cilostazolhsa04657IL-17 signaling pathway1.40E-0713P25963, P08238, O00463, Q07955, Q16539, P49841, P09341, P14780, P04141, P80188, P01375, P06702, P01584NFKBIA, HSP90AB1, TRAF5, SFRS1, MAPK14, GSK3B, CXCL1, MMP9, CSF2, LCN2, TNF, S100A9, IL1BMore
Cilostazolhsa04658Th1 and Th2 cell differentiation2.21E-1314Q04759, P07766, P20963, P09693, Q16539, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P13765, P23458, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, JAK1, RUNX3More
Cilostazolhsa04659Th17 cell differentiation1.75E-1222P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, P40189, Q9UL17, P23771, P84022, Q13485, P01584, P08238, P07766, P09693, P20963, P23458NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, IL6ST, TBX21, GATA3, SMAD3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Cilostazolhsa04660T cell receptor signaling pathway7.74E-1220P01375, P04141, P25963, Q9UDY8, Q04759, P10747, O95267, Q08881, P19174, P16333, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P29350, Q16539, P49841TNF, CSF2, NFKBIA, MALT1, PRKCQ, CD28, RASGRP1, ITK, PLCG1, NCK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, PTPN6, MAPK14, GSK3BMore
Cilostazolhsa04662B cell receptor signaling pathway1.17E-045P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Cilostazolhsa04664Fc epsilon RI signaling pathway1.62E-047P01375, Q16539, P42338, Q9UQC2, P07948, P19174, P09917TNF, MAPK14, PIK3CB, GAB2, LYN, PLCG1, ALOX5More
Cilostazolhsa04666Fc gamma R-mediated phagocytosis2.97E-037O75015, P42338, P23528, P06396, O14494, P14598, P17252FCGR3B, PIK3CB, CFL1, GSN, PLPP1, NCF1, PRKCAMore
Cilostazolhsa04668TNF signaling pathway2.21E-025P01375, O00463, Q16539, P20749, P14780TNF, TRAF5, MAPK14, BCL3, MMP9More
Cilostazolhsa04713Circadian entrainment3.66E-036P0DP23, P17252, P62873, Q08828, P51828, O15055CALM1, PRKCA, GNB1, ADCY1, ADCY7, PER2More
Cilostazolhsa04720Long-term potentiation2.59E-056P16298, P0DP23, P51812, P18848, Q08828, Q02750PPP3CB, CALM1, RPS6KA3, ATF4, ADCY1, MAP2K1More
Cilostazolhsa04721Synaptic vesicle cycle1.80E-022Q13488, P31645TCIRG1, SLC6A4More
Cilostazolhsa04723Retrograde endocannabinoid signaling1.75E-025Q14643, P17252, P22694, Q16539, Q16718ITPR1, PRKCA, PRKACB, MAPK14, NDUFA5More
Cilostazolhsa04724Glutamatergic synapse5.94E-034O15399, P63218, P50151, P15104GRIN2D, GNG5, GNG10, GLULMore
Cilostazolhsa04725Cholinergic synapse1.34E-037Q08828, P51828, P63218, P50151, P18848, P42338, P31751ADCY1, ADCY7, GNG5, GNG10, ATF4, PIK3CB, AKT2More
Cilostazolhsa04727GABAergic synapse1.63E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
Cilostazolhsa04728Dopaminergic synapse7.83E-035P31751, P18848, Q13362, Q14738, P0DP23AKT2, ATF4, PPP2R5C, PPP2R5D, CALM1More
Cilostazolhsa04744Phototransduction1.18E-022P62873, P0DP23GNB1, CALM1More
Cilostazolhsa04750Inflammatory mediator regulation of TRP channels5.91E-0510P14778, P01584, Q08828, P51828, P22694, Q16539, Q14643, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, MAPK14, ITPR1, PRKCQ, CALM2, CALM1More
Cilostazolhsa04911Insulin secretion2.63E-046Q08828, P51828, P63092, Q99941, P18848, Q13557ADCY1, ADCY7, GNAS, CREBL1, ATF4, CAMK2DMore
Cilostazolhsa04912GnRH signaling pathway6.62E-0510P17252, Q08828, P51828, P18848, Q16539, Q9Y6R4, Q14643, P0DP24, P0DP23, P22694PRKCA, ADCY1, ADCY7, ATF4, MAPK14, MAP3K4, ITPR1, CALM2, CALM1, PRKACBMore
Cilostazolhsa04913Ovarian steroidogenesis2.52E-021P06213INSRMore
Cilostazolhsa04914Progesterone-mediated oocyte maturation7.61E-067Q17RY0, P42338, Q13370, Q9Y6D9, P08238, P51812, Q02750CPEB4, PIK3CB, PDE3B, MAD1L1, HSP90AB1, RPS6KA3, MAP2K1More
Cilostazolhsa04915Estrogen signaling pathway2.01E-037P18848, Q08828, P51828, P31751, P0DMV8, P0DP23, Q15788ATF4, ADCY1, ADCY7, AKT2, HSPA1A, CALM1, NCOA1More
Cilostazolhsa04916Melanogenesis2.40E-023P0DP23, Q08828, P51828CALM1, ADCY1, ADCY7More
Cilostazolhsa04923Regulation of lipolysis in adipocytes7.59E-044Q08828, P51828, P06213, P31751ADCY1, ADCY7, INSR, AKT2More
Cilostazolhsa04924Renin secretion3.77E-022Q13370, P0DP23PDE3B, CALM1More
Cilostazolhsa04925Aldosterone synthesis and secretion4.27E-047Q99941, P18848, Q08828, P51828, P0DP23, P63092, Q13557CREBL1, ATF4, ADCY1, ADCY7, CALM1, GNAS, CAMK2DMore
Cilostazolhsa04926Relaxin signaling pathway3.95E-049P31751, P42338, P63218, P50151, P18848, P49767, Q08828, P51828, P49407AKT2, PIK3CB, GNG5, GNG10, ATF4, VEGFC, ADCY1, ADCY7, ARRB1More
Cilostazolhsa04927Cortisol synthesis and secretion8.61E-045Q99941, P18848, Q08828, P51828, P63092CREBL1, ATF4, ADCY1, ADCY7, GNASMore
Cilostazolhsa04928Parathyroid hormone synthesis, secretion and action2.66E-039Q14643, P63092, P22694, P23771, P17252, P61586, Q99941, P18848, P10415ITPR1, GNAS, PRKACB, GATA3, PRKCA, RHOA, CREBL1, ATF4, BCL2More
Cilostazolhsa04929GnRH secretion4.62E-022P42338, P49407PIK3CB, ARRB1More
Cilostazolhsa04930Type II diabetes mellitus3.14E-021P06213INSRMore
Cilostazolhsa04932Non-alcoholic fatty liver disease4.38E-048P31751, O43521, P18848, O75460, P01584, P13073, P12074, O95298AKT2, BCL2L11, ATF4, ERN1, IL1B, COX4I1, COX6A1, NDUFC2More
Cilostazolhsa04933AGE-RAGE signaling pathway in diabetic complications1.07E-049P84022, Q13485, P42224, P10415, P42338, Q12778, P49767, P17252, P19174SMAD3, SMAD4, STAT1, BCL2, PIK3CB, FOXO1, VEGFC, PRKCA, PLCG1More
Cilostazolhsa04934Cushing syndrome1.97E-047Q99941, P18848, Q08828, P51828, P63092, O15169, Q13557CREBL1, ATF4, ADCY1, ADCY7, GNAS, AXIN1, CAMK2DMore
Cilostazolhsa04935Growth hormone synthesis, secretion and action1.88E-024Q08828, P51828, P18848, P31751ADCY1, ADCY7, ATF4, AKT2More
Cilostazolhsa04940Type I diabetes mellitus4.18E-023P10747, P13765, P01375CD28, HLA-DOB, TNFMore
Cilostazolhsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Cilostazolhsa04970Salivary secretion1.89E-033Q08828, P51828, P0DP23ADCY1, ADCY7, CALM1More
Cilostazolhsa04971Gastric acid secretion2.54E-034Q08828, P51828, P15311, P0DP23ADCY1, ADCY7, VIL2, CALM1More
Cilostazolhsa04974Protein digestion and absorption2.78E-021P02452COL1A1More
Cilostazolhsa04975Fat digestion and absorption9.50E-041O14494PLPP1More
Cilostazolhsa04976Bile secretion2.10E-046O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Cilostazolhsa05010Alzheimer disease2.35E-0416Q92542, O15239, O95298, P05496, Q00535, O75460, P0DP23, P01584, P18848, O15169, P31751, P05141, P12236, P28070, P43686, P62195NCSTN, NDUFA1, NDUFC2, ATP5G1, CDK5, ERN1, CALM1, IL1B, ATF4, AXIN1, AKT2, SLC25A5, SLC25A6, PSMB4, PSMC4, PSMC5More
Cilostazolhsa05012Parkinson disease3.50E-0415O15239, Q16718, O14521, P05496, P05141, P12236, P63092, P18848, P43686, P62195, P19174, P0DP23, Q13557, Q13509, P68371NDUFA1, NDUFA5, SDHD, ATP5G1, SLC25A5, SLC25A6, GNAS, ATF4, PSMC4, PSMC5, PLCG1, CALM1, CAMK2D, TUBB3, TUBB2CMore
Cilostazolhsa05014Amyotrophic lateral sclerosis3.92E-028P20333, O15239, P05496, P18848, P43686, P62195, P51991, P35658TNFRSF1B, NDUFA1, ATP5G1, ATF4, PSMC4, PSMC5, HNRPA3, NUP214More
Cilostazolhsa05016Huntington disease1.76E-0310O95298, P13073, P12074, P24928, P30876, P62487, P05141, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, SLC25A5, ERN1, PSMB4, PSMD12More
Cilostazolhsa05017Spinocerebellar ataxia3.94E-024O75460, P31751, P28070, P05141ERN1, AKT2, PSMB4, SLC25A5More
Cilostazolhsa05020Prion disease1.15E-029P46531, O15239, P05496, P18848, P05141, P12236, P43686, P62195, Q99941NOTCH1, NDUFA1, ATP5G1, ATF4, SLC25A5, SLC25A6, PSMC4, PSMC5, CREBL1More
Cilostazolhsa05022Pathways of neurodegeneration - multiple diseases9.35E-0525Q13509, P68371, O15239, Q16718, O95298, O14521, P05496, Q8TEV9, O75460, P18848, Q13561, P19174, P05141, P12236, P17252, P20333, Q00535, O15169, P01584, Q08752, P0DP23, Q13557, P28070, P43686, P62195TUBB3, TUBB2C, NDUFA1, NDUFA5, NDUFC2, SDHD, ATP5G1, SMCR8, ERN1, ATF4, DCTN2, PLCG1, SLC25A5, SLC25A6, PRKCA, TNFRSF1B, CDK5, AXIN1, IL1B, PPID, CALM1, CAMK2D, PSMB4, PSMC4, PSMC5More
Cilostazolhsa05030Cocaine addiction2.40E-023P63092, Q99941, P18848GNAS, CREBL1, ATF4More
Cilostazolhsa05031Amphetamine addiction4.47E-034Q13557, P63092, Q99941, P18848CAMK2D, GNAS, CREBL1, ATF4More
Cilostazolhsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Cilostazolhsa05100Bacterial invasion of epithelial cells4.54E-023Q14141, Q05397, Q96JJ3SEPT6, PTK2, ELMO2More
Cilostazolhsa05110Vibrio cholerae infection2.60E-034Q13488, Q99437, P17252, P19174TCIRG1, ATP6V0B, PRKCA, PLCG1More
Cilostazolhsa05120Epithelial cell signaling in Helicobacter pylori infection2.32E-034Q16539, P09341, P25024, P25025MAPK14, CXCL1, CXCR1, CXCR2More
Cilostazolhsa05131Shigellosis2.93E-026Q9NQL2, P0CG47, Q14141, Q96JJ3, Q05397, Q13315RRAGD, UBB, SEPT6, ELMO2, PTK2, ATMMore
Cilostazolhsa05132Salmonella infection6.34E-0714P25963, P08238, Q9UJU2, Q13546, Q13489, P10415, P04406, O75369, Q9BQS8, Q13561, O60282, Q13509, P68371, P49754NFKBIA, HSP90AB1, LEF1, RIPK1, BIRC3, BCL2, GAPDH, FLNB, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2C, VPS41More
Cilostazolhsa05134Legionellosis2.82E-023P01584, Q9NR31, P0DMV8IL1B, SAR1A, HSPA1AMore
Cilostazolhsa05140Leishmaniasis1.58E-1015P13612, O75015, P14598, P23458, P42224, P13765, O60603, P25963, P01375, P01584, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Cilostazolhsa05144Malaria7.51E-069P60033, P69905, P68871, O60603, P01375, P35443, P01584, P10145, P26718CD81, HBA2, HBB, TLR2, TNF, THBS4, IL1B, IL8, KLRK1More
Cilostazolhsa05145Toxoplasmosis2.87E-035P25963, P10415, Q13489, P28068, Q16787NFKBIA, BCL2, BIRC3, HLA-DMB, LAMA3More
Cilostazolhsa05146Amoebiasis3.68E-1010P01584, P09341, P14778, P27930, P01375, O60603, P05089, P22694, P12814, P08311IL1B, CXCL1, IL1R1, IL1R2, TNF, TLR2, ARG1, PRKACB, ACTN1, CTSGMore
Cilostazolhsa05150Staphylococcus aureus infection2.17E-0411P0C0L4, P21730, P21462, O75015, P13765, Q16581, P13646, Q14532, P59665, P59666, P49913C4A, C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, KRT13, KRT32, DEFA1; DEFA1B, DEFA3, CAMPMore
Cilostazolhsa05152Tuberculosis5.80E-0413Q13488, Q99437, O75015, P48382, O60603, P01375, P10415, P13765, P25774, P49913, Q9UDY8, Q16539, P51617TCIRG1, ATP6V0B, FCGR3B, RFX5, TLR2, TNF, BCL2, HLA-DOB, CTSS, CAMP, MALT1, MAPK14, IRAK1More
Cilostazolhsa05160Hepatitis C4.34E-035Q13546, P01568, O00501, P29728, P01106RIPK1, IFNA21, CLDN5, OAS2, MYCMore
Cilostazolhsa05161Hepatitis B8.49E-034P25963, Q13485, P10415, P84022NFKBIA, SMAD4, BCL2, SMAD3More
Cilostazolhsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Cilostazolhsa05163Human cytomegalovirus infection5.04E-0717P31751, P01375, Q14643, P0DP23, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, P18848, P04637, O00463AKT2, TNF, ITPR1, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, ATF4, TP53, TRAF5More
Cilostazolhsa05164Influenza A4.49E-025P31751, P01584, P23458, P05141, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, NXF1More
Cilostazolhsa05165Human papillomavirus infection7.33E-057P02452, P24821, Q16787, P01568, Q02930, P04628, Q13315COL1A1, TNC, LAMA3, IFNA21, CREB5, WNT1, ATMMore
Cilostazolhsa05166Human T-cell leukemia virus 1 infection5.15E-0310P23458, P05141, P62826, Q08828, P51828, P18848, Q02930, P31751, P28068, Q13315JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, CREB5, AKT2, HLA-DMB, ATMMore
Cilostazolhsa05167Kaposi sarcoma-associated herpesvirus infection3.10E-0412P01568, P42224, P25963, P40189, P62873, P62879, P19174, P16298, Q02750, P04141, P0DP23, P0CG47IFNA21, STAT1, NFKBIA, IL6ST, GNB1, GNB2, PLCG1, PPP3CB, MAP2K1, CSF2, CALM1, UBBMore
Cilostazolhsa05168Herpes simplex virus 1 infection3.29E-0516P25963, P01568, Q9GZY0, P42224, Q07955, Q01130, Q13243, P42338, Q9Y2A4, Q13398, P51522, P17038, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, NXF2; NXF2B, STAT1, SFRS1, SFRS2, SFRS5, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212More
Cilostazolhsa05169Epstein-Barr virus infection7.34E-0514P13765, P01106, Q13547, O00463, P42338, P07948, Q13761, P24522, O75293, P01375, P29728, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, PIK3CB, LYN, RUNX3, GADD45A, GADD45B, TNF, OAS2, CD3E, CD3G, CD247More
Cilostazolhsa05170Human immunodeficiency virus 1 infection8.40E-046Q02750, P62879, P16298, Q05397, Q13315, P20333MAP2K1, GNB2, PPP3CB, PTK2, ATM, TNFRSF1BMore
Cilostazolhsa05171Coronavirus disease - COVID-191.36E-027P25963, P42224, P01568, P40189, P04141, P19174, P17252NFKBIA, STAT1, IFNA21, IL6ST, CSF2, PLCG1, PRKCAMore
Cilostazolhsa05200Pathways in cancer8.42E-0526Q13751, P42338, P08238, P42224, P25963, P19174, P17252, P43246, P84022, Q13485, Q13547, P14923, P30281, P49767, Q12778, P43657, P62873, P63218, P50151, Q14344, Q7LDG7, O75293, P0DP23, P01568, P14784, P40189LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, PRKCA, MSH2, SMAD3, SMAD4, HDAC1, JUP, CCND3, VEGFC, FOXO1, P2RY5, GNB1, GNG5, GNG10, GNA13, RASGRP2, GADD45B, CALM1, IFNA21, IL2RB, IL6STMore
Cilostazolhsa05202Transcriptional misregulation in cancer1.06E-0823Q12778, Q15532, Q13315, P41732, P17844, P14780, P27930, P14923, Q15744, Q16548, Q13489, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, SS18, ATM, TSPAN7, DDX5, MMP9, IL1R2, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Cilostazolhsa05203Viral carcinogenesis2.32E-038Q99941, P18848, P27348, Q15283, P61586, P61978, P62807, O60814CREBL1, ATF4, YWHAQ, RASA2, RHOA, HNRPK, HIST1H2BC, H2BC12More
Cilostazolhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Cilostazolhsa05206MicroRNAs in cancer1.54E-026P21860, P61978, P46531, P63279, P22105, P61586ERBB3, HNRPK, NOTCH1, UBE2I, TNXB, RHOAMore
Cilostazolhsa05210Colorectal cancer1.49E-035Q9UKG1, P84022, Q13485, P10415, P37173APPL1, SMAD3, SMAD4, BCL2, TGFBR2More
Cilostazolhsa05212Pancreatic cancer1.59E-058P42338, P31751, Q15311, P23458, P42224, P84022, Q13485, O75293PIK3CB, AKT2, RALBP1, JAK1, STAT1, SMAD3, SMAD4, GADD45BMore
Cilostazolhsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Cilostazolhsa05214Glioma4.79E-045P0DP23, P17252, P42338, P19174, O75293CALM1, PRKCA, PIK3CB, PLCG1, GADD45BMore
Cilostazolhsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
Cilostazolhsa05217Basal cell carcinoma7.91E-035Q13635, P04628, P49841, Q9UJU2, P24522PTCH1, WNT1, GSK3B, LEF1, GADD45AMore
Cilostazolhsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Cilostazolhsa05220Chronic myeloid leukemia1.44E-036Q13547, Q13485, P25963, P84022, P42338, O75293HDAC1, SMAD4, NFKBIA, SMAD3, PIK3CB, GADD45BMore
Cilostazolhsa05222Small cell lung cancer1.50E-023Q13489, P10415, P25963BIRC3, BCL2, NFKBIAMore
Cilostazolhsa05223Non-small cell lung cancer1.39E-023P10826, Q9HC35, O75293RARB, EML4, GADD45BMore
Cilostazolhsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Cilostazolhsa05226Gastric cancer4.33E-035Q02750, O15169, P84022, Q13485, P10415MAP2K1, AXIN1, SMAD3, SMAD4, BCL2More
Cilostazolhsa05231Choline metabolism in cancer2.11E-048P31751, Q9NRA1, Q9Y259, P19174, P23743, Q16760, O14986, P17252AKT2, PDGFC, CHKB, PLCG1, DGKA, DGKD, PIP5K1B, PRKCAMore
Cilostazolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.01E-0716P25963, O95267, P19174, P07766, P20963, P09693, P06239, P29350, P23458, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730NFKBIA, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PTPN6, JAK1, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Cilostazolhsa05310Asthma5.91E-073P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Cilostazolhsa05321Inflammatory bowel disease1.25E-128O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1B, IL21RMore
Cilostazolhsa05322Systemic lupus erythematosus1.24E-0413O75015, P08246, P08311, P09871, P01375, P10747, P13765, Q6FI13, Q93077, P62807, O60814, P68431, P05455FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, SSBMore
Cilostazolhsa05332Graft-versus-host disease8.46E-095P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Cilostazolhsa05340Primary immunodeficiency1.31E-045P01730, P01732, P11912, P07766, P06239CD4, CD8A, CD79A, CD3E, LCKMore
Cilostazolhsa05415Diabetic cardiomyopathy8.76E-0514P17252, P30405, P05141, P12236, P14598, Q15080, O15239, Q16718, O14521, P05496, Q13557, P37173, P04406, P26678PRKCA, PPIF, SLC25A5, SLC25A6, NCF1, NCF4, NDUFA1, NDUFA5, SDHD, ATP5G1, CAMK2D, TGFBR2, GAPDH, PLNMore
Cilostazolhsa05418Fluid shear stress and atherosclerosis3.33E-0612Q16539, P42338, Q14145, P14598, P10599, P14780, P01375, P04637, P14778, P27930, P0DP23, P08238MAPK14, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2, CALM1, HSP90AB1More

Community members of Cilostazol (SDC: 9.14)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
Q13546RIPK1ReceptorNoneinteracting serine/threonineNoneprotein kinase 1Predicted10.51990.41830.8431.9396
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
P22894MMP8Neutrophil collagenasePredicted10.10610.35700.767
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
P14780MMP9Matrix metalloproteinaseNone9Predicted10.16960.84240.73152.5012
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
Q04759PRKCQProtein kinase C theta typePredicted00.04050.42440.61731.4864
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P20839IMPDH1InosineNone5'Nonemonophosphate dehydrogenase 1Predicted00.19280.13070.16530.5231
P25774CTSSCathepsin SPredicted00.31850.49320.51681.6625
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
Q16769QPCTGlutaminylNonepeptide cyclotransferasePredicted00.02450.241600.4954
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
Q9HAZ1CLK4Dual specificity protein kinase CLK4Predicted00.28830.31110.15870.9251
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
P49760CLK2Dual specificity protein kinase CLK2Predicted00.03030.295100.6053
Q15078CDK5R1CyclinNonedependent kinase 5 activator 1Predicted00.13580.50040.25751.3263
Q15722LTB4RLeukotriene B4 receptor 1Predicted00.06770.219900.4736
P49768PSEN1PresenilinNone1Predicted10.26770.65990.33081.7845
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
O75469NR1I2Nuclear receptor subfamily 1 group I member 2Predicted10.03150.949301.9143
P13866SLC5A1Sodium/glucose cotransporter 1Predicted00.37190.11050.1050.512
P37173TGFBR2TGFNonebeta receptor typeNone2Predicted00.28670.3790.87421.7755
P11511CYP19A1AromatasePredicted00.815610.15882.5666
O00767SCDStearoylNoneCoA desaturasePredicted10.16860.1870.19970.6581
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P40926MDH2Malate dehydrogenase, mitochondrialPredicted00.47210.16110.24740.8055
P51812RPS6KA3Ribosomal protein S6 kinase alphaNone3Predicted00.28650.39360.41461.345
Q13370PDE3BcGMPNoneinhibited 3',5'Nonecyclic phosphodiesterase BPredicted00.09060.16140.35580.7239
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)