PharmaCoNets

PharmaCoNets of Azacitidine (S_PCN: 72.63 )

Azacitidine regulated-network (S_DN: 19.01)

Drug Name

Pathway ID

Pathway name

P-value

No. of gene members

UniProt AC

Gene name

Detail of Coexpression

Azacitidine

hsa00010

Glycolysis / Gluconeogenesis

4.41E-02

P04075, P06733, P04406, P60174

ALDOA, ENO1, GAPDH, TPI1

Azacitidine

hsa00030

Pentose phosphate pathway

1.95E-02

P51854, P08237, P37837

TKTL1, PFKM, TALDO1

Azacitidine

hsa00051

Fructose and mannose metabolism

2.21E-02

O14772, P60174, P04075

FPGT, TPI1, ALDOA

Azacitidine

hsa00052

Galactose metabolism

4.27E-02

P06280, O43451

GLA, MGAM

Azacitidine

hsa00120

Primary bile acid biosynthesis

3.72E-02

P22680, P22307

CYP7A1, SCP2

Azacitidine

hsa00240

Pyrimidine metabolism

8.44E-04

P31350, P21589, P32320, P04183

RRM2, NT5E, CDA, TK1

Azacitidine

hsa00280

Valine, leucine and isoleucine degradation

3.41E-03

P55809, Q9HCC0, Q02252, P11310

OXCT1, MCCC2, ALDH6A1, ACADM

Azacitidine

hsa00500

Starch and sucrose metabolism

6.17E-03

O43451, P46976, P06737

MGAM, GYG1, PYGL

Azacitidine

hsa00531

Glycosaminoglycan degradation

4.51E-02

P22304, P06865

IDS, HEXA

Azacitidine

hsa00630

Glyoxylate and dicarboxylate metabolism

1.58E-07

P40925, P15104

MDH1, GLUL

Azacitidine

hsa00730

Thiamine metabolism

2.27E-02

P05186, P24666

ALPL, ACP1

Azacitidine

hsa00980

Metabolism of xenobiotics by cytochrome P450

3.20E-02

P78417, P11766

GSTO1, ADH5

Azacitidine

hsa00982

Drug metabolism - cytochrome P450

3.20E-02

P78417, P11766

GSTO1, ADH5

Azacitidine

hsa00983

Drug metabolism - other enzymes

3.83E-04

P04183, P32320, P31350, P05164

TK1, CDA, RRM2, MPO

Azacitidine

hsa01040

Biosynthesis of unsaturated fatty acids

4.28E-02

P22307

SCP2

Azacitidine

hsa01100

Metabolic pathways

1.03E-02

Q9Y234, P35790, Q16772, P15144, P30041, O14732, Q02153, Q16774, P20839, P00918, P10768, P55809, P06280, Q9Y6K0, P08237, P21399, Q9UHK6, P51854, Q86VZ5, Q9BVK2, P15907, O96024, P37837, P50213, P43490, Q969G6, Q13029, Q9NVH6

LIPT1, CHKA, GSTA3, ANPEP, PRDX6, IMPA2, GUCY1B3, GUK1, IMPDH1, CA2, ESD, OXCT1, GLA, CEPT1, PFKM, ACO1, AMACR, TKTL1, SGMS1, ALG8, ST6GAL1, B3GALT4, TALDO1, IDH3A, PBEF1, RFK, PRDM2, TMLHE

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q9Y234	LIPT1	Lipoyltransferase 1, mitochondrial	0.778
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P35790	CHKA	Choline kinase alpha	-0.856
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q16772	GSTA3	Glutathione S-transferase A3	-0.768
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P15144	ANPEP	Aminopeptidase N	0.846
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P30041	PRDX6	Peroxiredoxin-6	0.785
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	O14732	IMPA2	Inositol monophosphatase 2	0.738
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q02153	GUCY1B3	Guanylate cyclase soluble subunit beta-1	-0.774
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q16774	GUK1	Guanylate kinase	0.757
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	1
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P00918	CA2	Carbonic anhydrase 2	0.772
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P10768	ESD	S-formylglutathione hydrolase	-0.701
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P55809	OXCT1	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial	-0.744
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P06280	GLA	Alpha-galactosidase A	0.728
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q9Y6K0	CEPT1	Choline/ethanolaminephosphotransferase 1	0.771
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P08237	PFKM	ATP-dependent 6-phosphofructokinase, muscle type	0.868
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P21399	ACO1	Cytoplasmic aconitate hydratase	-0.739
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q9UHK6	AMACR	Alpha-methylacyl-CoA racemase	-0.784
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P51854	TKTL1	Transketolase-like protein 1	-0.753
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q86VZ5	SGMS1	Phosphatidylcholine:ceramide cholinephosphotransferase 1	-0.81
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q9BVK2	ALG8	Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase	-0.726
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P15907	ST6GAL1	Beta-galactoside alpha-2,6-sialyltransferase 1	-0.827
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	O96024	B3GALT4	Beta-1,3-galactosyltransferase 4	0.797
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P37837	TALDO1	Transaldolase	0.732
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P50213	IDH3A	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	-0.732
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	P43490	PBEF1	Nicotinamide phosphoribosyltransferase	0.702
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q969G6	RFK	Riboflavin kinase	0.705
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q13029	PRDM2	PR domain zinc finger protein 2	0.744
P20839	IMPDH1	Inosine-5'-monophosphate dehydrogenase 1	Q9NVH6	TMLHE	Trimethyllysine dioxygenase, mitochondrial	-0.721

Azacitidine

hsa01200

Carbon metabolism

3.30E-04

P04075, P51854, P04406, P08237, P60174, P37837, P06733, O14521, Q9P2R7, P50213, P21399, P10768, Q02252

ALDOA, TKTL1, GAPDH, PFKM, TPI1, TALDO1, ENO1, SDHD, SUCLA2, IDH3A, ACO1, ESD, ALDH6A1

Azacitidine

hsa01210

2-Oxocarboxylic acid metabolism

1.73E-02

P21399, P50213

ACO1, IDH3A

Azacitidine

hsa01230

Biosynthesis of amino acids

2.08E-04

P60174, P04406, P06733, P04075, P08237, P51854, Q99707, P21399, P50213, P37837

TPI1, GAPDH, ENO1, ALDOA, PFKM, TKTL1, MTR, ACO1, IDH3A, TALDO1

Azacitidine

hsa01522

Endocrine resistance

2.84E-02

P22694, Q9UM47, P46527

PRKACB, NOTCH3, CDKN1B

Azacitidine

hsa01524

Platinum drug resistance

7.33E-03

Q13489, P98170, P78417, P43246, P52701

BIRC3, BIRC4, GSTO1, MSH2, MSH6

Azacitidine

hsa03013

RNA transport

4.13E-02

Q09161, P35658, P47813, Q14152, O75822, P51114

NCBP1, NUP214, EIF1AX, EIF3A, EIF3J, FXR1

Azacitidine

hsa03040

Spliceosome

3.85E-07

Q14562, O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, O43447

DHX8, DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, PPIH

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Q14562	DHX8	ATP-dependent RNA helicase DHX8	-0.708
P29375	JARID1A	Lysine-specific demethylase 5A	Q14562	DHX8	ATP-dependent RNA helicase DHX8	0.781
P11142	HSPA8	Heat shock cognate 71 kDa protein	Q14562	DHX8	ATP-dependent RNA helicase DHX8	0.732
P29375	JARID1A	Lysine-specific demethylase 5A	O43143	DHX15	ATP-dependent RNA helicase DHX15	0.794
P11142	HSPA8	Heat shock cognate 71 kDa protein	O43143	DHX15	ATP-dependent RNA helicase DHX15	0.789
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	O43143	DHX15	ATP-dependent RNA helicase DHX15	-0.809
P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	O60508	CDC40	Pre-mRNA-processing factor 17	-0.837
P29375	JARID1A	Lysine-specific demethylase 5A	O60508	CDC40	Pre-mRNA-processing factor 17	0.875
P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	P08579	SNRPB2	U2 small nuclear ribonucleoprotein B''	-0.702
P11142	HSPA8	Heat shock cognate 71 kDa protein	P08579	SNRPB2	U2 small nuclear ribonucleoprotein B''	0.752
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P08579	SNRPB2	U2 small nuclear ribonucleoprotein B''	-0.811
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P26368	U2AF2	Splicing factor U2AF 65 kDa subunit	-0.702
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	Q13595	TRA2A	Transformer-2 protein homolog alpha	-0.879
P29375	JARID1A	Lysine-specific demethylase 5A	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.725
P11142	HSPA8	Heat shock cognate 71 kDa protein	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.824
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	-0.806
P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	-0.835
P29375	JARID1A	Lysine-specific demethylase 5A	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.862
P11142	HSPA8	Heat shock cognate 71 kDa protein	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.701
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P84103	SFRS3	Serine/arginine-rich splicing factor 3	-0.703
P29375	JARID1A	Lysine-specific demethylase 5A	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.732
P11142	HSPA8	Heat shock cognate 71 kDa protein	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.772
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	-0.731
P11142	HSPA8	Heat shock cognate 71 kDa protein	P11142	HSPA8	Heat shock cognate 71 kDa protein	1
P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	O43447	PPIH	Peptidyl-prolyl cis-trans isomerase H	-0.761
P11142	HSPA8	Heat shock cognate 71 kDa protein	O43447	PPIH	Peptidyl-prolyl cis-trans isomerase H	0.872

Azacitidine

hsa04020

Calcium signaling pathway

5.11E-04

P27987, P21796, P45880, Q13557, P30679, P19174, P0DP23, P05141, P23634

ITPKB, VDAC1, VDAC2, CAMK2D, GNA15, PLCG1, CALM1, SLC25A5, ATP2B4

Azacitidine

hsa04022

cGMP-PKG signaling pathway

2.26E-03

Q14814, Q99941, P18848, P05141, P21796, P45880, P0DP23, P01042

MEF2D, CREBL1, ATF4, SLC25A5, VDAC1, VDAC2, CALM1, KNG1

Azacitidine

hsa04024

cAMP signaling pathway

4.38E-02

P42338, P0DP23, Q13370, Q13009

PIK3CB, CALM1, PDE3B, TIAM1

Azacitidine

hsa04061

Viral protein interaction with cytokine and cytokine receptor

4.28E-02

P51684, P09341, P25024, P25025, P47992, Q9UBD3, P01375

CCR6, CXCL1, CXCR1, CXCR2, XCL1, XCL2, TNF

Azacitidine

hsa04062

Chemokine signaling pathway

3.81E-02

P07948, P62873, P63218, P50151, P43250, Q13009

LYN, GNB1, GNG5, GNG10, GRK6, TIAM1

Azacitidine

hsa04064

NF-kappa B signaling pathway

2.37E-04

P10415, P51617, O00463, P01375, Q04759, Q9UDY8, Q13077, Q16548, Q13315, P24522, P09341

BCL2, IRAK1, TRAF5, TNF, PRKCQ, MALT1, TRAF1, BCL2A1, ATM, GADD45A, CXCL1

Azacitidine

hsa04070

Phosphatidylinositol signaling system

1.67E-03

P19174, P0DP23, P42338, O14986, P23743, P27987

PLCG1, CALM1, PIK3CB, PIP5K1B, DGKA, ITPKB

Azacitidine

hsa04071

Sphingolipid signaling pathway

1.39E-03

P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415

S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2

Azacitidine

hsa04072

Phospholipase D signaling pathway

3.55E-02

Q9UQC2, Q8WYR1, Q15438, P51828

GAB2, PIK3R5, PSCD1, ADCY7

Azacitidine

hsa04115

p53 signaling pathway

3.35E-03

P24522, Q13315, P31350, O95067, P10415

GADD45A, ATM, RRM2, CCNB2, BCL2

Azacitidine

hsa04141

Protein processing in endoplasmic reticulum

6.42E-03

P18848, P30101, Q15437, Q15436, Q99941, P11142, P07900, P08238

ATF4, PDIA3, SEC23B, SEC23A, CREBL1, HSPA8, HSP90AA1, HSP90AB1

Azacitidine

hsa04142

Lysosome

3.32E-03

P06865, P22304, Q13510, P07602, P61916, Q04900

HEXA, IDS, ASAH1, PSAP, NPC2, CD164

Azacitidine

hsa04145

Phagosome

1.73E-03

Q15080, P68371, P05164, P78380, P35443, P13765

NCF4, TUBB2C, MPO, OLR1, THBS4, HLA-DOB

Azacitidine

hsa04151

PI3K-Akt signaling pathway

1.24E-02

P62753, P27348, P07900, P08238, P62873, P63218, Q16363, P22105, P14784, Q99941, P18848, P30279

RPS6, YWHAQ, HSP90AA1, HSP90AB1, GNB1, GNG5, LAMA4, TNXB, IL2RB, CREBL1, ATF4, CCND2

Azacitidine

hsa04213

Longevity regulating pathway - multiple species

3.03E-02

P51828, P0DMV8

ADCY7, HSPA1A

Azacitidine

hsa04217

Necroptosis

4.49E-04

P01568, Q13489, P98170, P42224, P07900, P08238, P15104, P05141, Q13557, P21796, P45880

IFNA21, BIRC3, BIRC4, STAT1, HSP90AA1, HSP90AB1, GLUL, SLC25A5, CAMK2D, VDAC1, VDAC2

Azacitidine

hsa04261

Adrenergic signaling in cardiomyocytes

3.85E-04

P67936, P07550, P51828, P22694, Q8WYR1, P18848, Q13362, P0DP24

TPM4, ADRB2, ADCY7, PRKACB, PIK3R5, ATF4, PPP2R5C, CALM2

Azacitidine

hsa04270

Vascular smooth muscle contraction

1.86E-02

P0DP24, P51828, P35579, P35749

CALM2, ADCY7, MYH9, MYH11

Azacitidine

hsa04310

Wnt signaling pathway

5.60E-03

P30279, Q13485, O43318

CCND2, SMAD4, MAP3K7

Azacitidine

hsa04330

Notch signaling pathway

3.28E-03

Q92542, P49768, Q92830, P78504

NCSTN, PSEN1, KAT2A, JAG1

Azacitidine

hsa04360

Axon guidance

1.71E-02

P20827, O95631, P42338, P23528

EFNA1, NTN1, PIK3CB, CFL1

Azacitidine

hsa04371

Apelin signaling pathway

6.46E-05

P62873, P63218, P50151, Q14344, Q13485, P84022, Q16566, P0DP23

GNB1, GNG5, GNG10, GNA13, SMAD4, SMAD3, CAMK4, CALM1

Azacitidine

hsa04380

Osteoclast differentiation

1.02E-02

Q9UQC2, Q16539, P14778, O75015, P01375, Q8N149

GAB2, MAPK14, IL1R1, FCGR3B, TNF, LILRA2

Azacitidine

hsa04520

Adherens junction

3.91E-02

Q13485, O43318

SMAD4, MAP3K7

Azacitidine

hsa04610

Complement and coagulation cascades

2.46E-02

P00734, P0C0L4, P21730

F2, C4A, C5AR1

Azacitidine

hsa04612

Antigen processing and presentation

4.72E-02

P13765, P48382, P26715, P26717

HLA-DOB, RFX5, KLRC1, KLRC2

Azacitidine

hsa04613

Neutrophil extracellular trap formation

1.02E-02

O60603, P05164, P08246, Q9UM07, Q6FI13, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539

TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14

Azacitidine

hsa04621

NOD-like receptor signaling pathway

5.72E-03

Q16539, Q14643, P25963, Q9H1Y0, P43490, O00463, P10415, Q05823, P01375, P09341, P49913, P12838

MAPK14, ITPR1, NFKBIA, ATG5, PBEF1, TRAF5, BCL2, RNASEL, TNF, CXCL1, CAMP, DEFA4

Azacitidine

hsa04625

C-type lectin receptor signaling pathway

3.87E-02

Q9ULY5, P20749, P01375, Q16539

CLEC4E, BCL3, TNF, MAPK14

Azacitidine

hsa04657

IL-17 signaling pathway

1.36E-02

O00463, Q16539, P49841, P14780, P01375

TRAF5, MAPK14, GSK3B, MMP9, TNF

Azacitidine

hsa04658

Th1 and Th2 cell differentiation

8.47E-03

Q04759, P20963, P09693, Q16539, Q14765, P23771, Q9UL17, P13765

PRKCQ, CD247, CD3G, MAPK14, STAT4, GATA3, TBX21, HLA-DOB

Azacitidine

hsa04659

Th17 cell differentiation

4.69E-03

P19174, P42224, P14784, P40189, P07900, P08238, P07766

PLCG1, STAT1, IL2RB, IL6ST, HSP90AA1, HSP90AB1, CD3E

Azacitidine

hsa04660

T cell receptor signaling pathway

2.57E-03

P01375, Q9UDY8, Q04759, P10747, O95267, Q08881, P20963, P09693, P01732, Q13191, Q16539

TNF, MALT1, PRKCQ, CD28, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, MAPK14

Azacitidine

hsa04662

B cell receptor signaling pathway

1.49E-03

P42338, P60033, P07948, P21854, Q8N149

PIK3CB, CD81, LYN, CD72, LILRA2

Azacitidine

hsa04664

Fc epsilon RI signaling pathway

2.20E-03

P01375, Q16539, P42338, Q9UQC2, P07948, P09917

TNF, MAPK14, PIK3CB, GAB2, LYN, ALOX5

Azacitidine

hsa04666

Fc gamma R-mediated phagocytosis

3.08E-02

P42338, P23528, P14598

PIK3CB, CFL1, NCF1

Azacitidine

hsa04668

TNF signaling pathway

2.21E-02

P01375, O00463, Q16539, P20749, P14780

TNF, TRAF5, MAPK14, BCL3, MMP9

Azacitidine

hsa04713

Circadian entrainment

3.99E-04

O15399, P0DP23, Q13557, P62873, P63218, P50151

GRIN2D, CALM1, CAMK2D, GNB1, GNG5, GNG10

Azacitidine

hsa04720

Long-term potentiation

2.33E-02

Q16566, P0DP23, O15399

CAMK4, CALM1, GRIN2D

Azacitidine

hsa04724

Glutamatergic synapse

1.82E-05

O15399, P62873, P63218, P50151, P15104

GRIN2D, GNB1, GNG5, GNG10, GLUL

Azacitidine

hsa04725

Cholinergic synapse

1.78E-04

P62873, P63218, P50151, P18848, Q16566, Q13557, P42338

GNB1, GNG5, GNG10, ATF4, CAMK4, CAMK2D, PIK3CB

Azacitidine

hsa04726

Serotonergic synapse

2.38E-02

P62873, P63218, P50151, P09917

GNB1, GNG5, GNG10, ALOX5

Azacitidine

hsa04727

GABAergic synapse

2.79E-05

P62873, P63218, P50151, P15104, P46459

GNB1, GNG5, GNG10, GLUL, NSF

Azacitidine

hsa04728

Dopaminergic synapse

1.87E-02

P62873, P63218, Q99941, P18848, Q13557, P0DP23

GNB1, GNG5, CREBL1, ATF4, CAMK2D, CALM1

Azacitidine

hsa04730

Long-term depression

3.20E-02

Q14344, P07948

GNA13, LYN

Azacitidine

hsa04740

Olfactory transduction

9.79E-03

P62873, Q13557, P0DP23

GNB1, CAMK2D, CALM1

Azacitidine

hsa04744

Phototransduction

1.49E-04

P62873, P0DP23

GNB1, CALM1

Azacitidine

hsa04750

Inflammatory mediator regulation of TRP channels

1.61E-02

Q13557, P19174, P24723, P0DP23, P01042

CAMK2D, PLCG1, PRKCH, CALM1, KNG1

Azacitidine

hsa04911

Insulin secretion

4.31E-02

P22694, P18848

PRKACB, ATF4

Azacitidine

hsa04914

Progesterone-mediated oocyte maturation

3.92E-02

P42338, Q13370, P08238

PIK3CB, PDE3B, HSP90AB1

Azacitidine

hsa04915

Estrogen signaling pathway

6.72E-04

Q99941, P18848, P51828, P07900, P08238, P0DMV8, P11142, P0DP24, P0DP23, Q15788

CREBL1, ATF4, ADCY7, HSP90AA1, HSP90AB1, HSPA1A, HSPA8, CALM2, CALM1, NCOA1

Azacitidine

hsa04918

Thyroid hormone synthesis

4.31E-02

P22694, P18848

PRKACB, ATF4

Azacitidine

hsa04921

Oxytocin signaling pathway

2.92E-02

P0DP24, P51828, Q96RR4, Q8WYR1

CALM2, ADCY7, CAMKK2, PIK3R5

Azacitidine

hsa04923

Regulation of lipolysis in adipocytes

4.31E-02

P22694, P07550

PRKACB, ADRB2

Azacitidine

hsa04924

Renin secretion

2.22E-03

P22694, P07550, Q13370, P0DP23

PRKACB, ADRB2, PDE3B, CALM1

Azacitidine

hsa04925

Aldosterone synthesis and secretion

3.35E-02

Q99941, P18848, P0DP23, Q13557

CREBL1, ATF4, CALM1, CAMK2D

Azacitidine

hsa04926

Relaxin signaling pathway

8.02E-04

P42338, P63218, P50151, P49767, P30679, P49407

PIK3CB, GNG5, GNG10, VEGFC, GNA15, ARRB1

Azacitidine

hsa04927

Cortisol synthesis and secretion

1.86E-02

P18848, P22694

ATF4, PRKACB

Azacitidine

hsa04929

GnRH secretion

4.62E-02

P42338, P49407

PIK3CB, ARRB1

Azacitidine

hsa04934

Cushing syndrome

2.84E-02

P18848, P22694, P46527

ATF4, PRKACB, CDKN1B

Azacitidine

hsa04940

Type I diabetes mellitus

2.99E-02

P10747, P01375

CD28, TNF

Azacitidine

hsa04970

Salivary secretion

1.23E-02

P07550, P22694, P49913

ADRB2, PRKACB, CAMP

Azacitidine

hsa05010

Alzheimer disease

4.56E-02

P19404, P13073, P0DP23, P18848, Q71U36, Q13509, P05141, P21796, P45880

NDUFV2, COX4I1, CALM1, ATF4, TUBA1A, TUBB3, SLC25A5, VDAC1, VDAC2

Azacitidine

hsa05012

Parkinson disease

6.70E-04

P19404, P13073, P05141, P21796, P45880, P18848, P19174, P0DP23, Q13557, Q71U36, Q13509

NDUFV2, COX4I1, SLC25A5, VDAC1, VDAC2, ATF4, PLCG1, CALM1, CAMK2D, TUBA1A, TUBB3

Azacitidine

hsa05016

Huntington disease

9.64E-03

P19404, P13073, Q13547, P30876, P62487, P05141, P21796, P45880, Q71U36, Q13509

NDUFV2, COX4I1, HDAC1, POLR2B, POLR2G, SLC25A5, VDAC1, VDAC2, TUBA1A, TUBB3

Azacitidine

hsa05017

Spinocerebellar ataxia

2.16E-02

Q8TB72, P21796

PUM2, VDAC1

Azacitidine

hsa05020

Prion disease

9.64E-03

P11142, P19404, P13073, P18848, P05141, P21796, P45880, Q71U36, Q13509, Q99941

HSPA8, NDUFV2, COX4I1, ATF4, SLC25A5, VDAC1, VDAC2, TUBA1A, TUBB3, CREBL1

Azacitidine

hsa05022

Pathways of neurodegeneration - multiple diseases

1.36E-02

Q71U36, Q13509, P19404, P13073, P21796, P18848, P19174, P05141, P45880, P20333, P0DP23, Q13557

TUBA1A, TUBB3, NDUFV2, COX4I1, VDAC1, ATF4, PLCG1, SLC25A5, VDAC2, TNFRSF1B, CALM1, CAMK2D

Azacitidine

hsa05030

Cocaine addiction

4.31E-02

P22694, P18848

PRKACB, ATF4

Azacitidine

hsa05031

Amphetamine addiction

6.57E-03

P0DP23, Q13557, Q99941, P18848, Q13547

CALM1, CAMK2D, CREBL1, ATF4, HDAC1

Azacitidine

hsa05032

Morphine addiction

3.52E-04

P62873, P63218, P50151, Q07343, P43250

GNB1, GNG5, GNG10, PDE4B, GRK6

Azacitidine

hsa05034

Alcoholism

1.63E-04

O15399, Q99941, P18848, Q16566, Q13547, P0DP23, P62873, P63218, P50151, Q93079, O60814

GRIN2D, CREBL1, ATF4, CAMK4, HDAC1, CALM1, GNB1, GNG5, GNG10, H2BC9, H2BC12

Azacitidine

hsa05134

Legionellosis

3.35E-02

P11215, P68104, P11142, P19875

ITGAM, EEF1A1, HSPA8, CXCL2

Azacitidine

hsa05144

Malaria

3.09E-02

P69905, P68871, O60603, P10145

HBA2, HBB, TLR2, IL8

Azacitidine

hsa05145

Toxoplasmosis

3.55E-02

P23458, Q8WYR1, P0DMV8

JAK1, PIK3R5, HSPA1A

Azacitidine

hsa05146

Amoebiasis

3.11E-02

P09341, P27930, P01375, O60603, P05089, P22694, P08311

CXCL1, IL1R2, TNF, TLR2, ARG1, PRKACB, CTSG

Azacitidine

hsa05150

Staphylococcus aureus infection

4.05E-04

P0C0L4, P21730, P21462, O75015, P13765, P13646, Q14532, P59665, P59666, P12838, P49913

C4A, C5AR1, FPR1, FCGR3B, HLA-DOB, KRT13, KRT32, DEFA1; DEFA1B, DEFA3, DEFA4, CAMP

Azacitidine

hsa05152

Tuberculosis

1.16E-03

O75015, P48382, O60603, P01375, P10415, P13765, P49913, Q9UDY8, Q16539, P51617

FCGR3B, RFX5, TLR2, TNF, BCL2, HLA-DOB, CAMP, MALT1, MAPK14, IRAK1

Azacitidine

hsa05163

Human cytomegalovirus infection

1.64E-03

P01375, P62873, P63218, P50151, P0DP23, P49841, P14778, P25025, Q16539, O00463, P30101, P01568

TNF, GNB1, GNG5, GNG10, CALM1, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5, PDIA3, IFNA21

Azacitidine

hsa05165

Human papillomavirus infection

9.48E-04

P46527, P35443, P01375, Q08999, Q9UM47, P22694, Q13362, Q13315

CDKN1B, THBS4, TNF, RBL2, NOTCH3, PRKACB, PPP2R5C, ATM

Azacitidine

hsa05166

Human T-cell leukemia virus 1 infection

4.93E-02

P22694, P18848, P25963, P25208, Q13315, P01375

PRKACB, ATF4, NFKBIA, NFYB, ATM, TNF

Azacitidine

hsa05167

Kaposi sarcoma-associated herpesvirus infection

1.98E-03

P01568, P42224, P62873, P63218, P50151, P19875, P19174, P07948, P0DP23

IFNA21, STAT1, GNB1, GNG5, GNG10, CXCL2, PLCG1, LYN, CALM1

Azacitidine

hsa05168

Herpes simplex virus 1 infection

1.78E-03

P01568, P42224, Q07955, Q01130, P84103, Q13243, Q13489, P30101, P42338, Q13398, Q03923, Q9NZL3, Q9UDV6

IFNA21, STAT1, SFRS1, SFRS2, SFRS3, SFRS5, BIRC3, PDIA3, PIK3CB, ZNF211, ZNF85, ZNF224, ZNF212

Azacitidine

hsa05169

Epstein-Barr virus infection

4.48E-03

Q13547, P42338, P07948, P30101, Q13761, O75293, P30279, P42224, P07766

HDAC1, PIK3CB, LYN, PDIA3, RUNX3, GADD45B, CCND2, STAT1, CD3E

Azacitidine

hsa05170

Human immunodeficiency virus 1 infection

3.76E-03

P62873, P63218, P50151, P0DP23, P01375, O00463, P30101, Q14643, P01568, Q16539, O60603, Q13315, P23528, P09693, P20963, P10415, Q93034, Q9Y6Q5

GNB1, GNG5, GNG10, CALM1, TNF, TRAF5, PDIA3, ITPR1, IFNA21, MAPK14, TLR2, ATM, CFL1, CD3G, CD247, BCL2, CUL5, AP1M2

Azacitidine

hsa05200

Pathways in cancer

6.25E-08

Q16363, Q13751, P42338, P07900, P08238, P42224, P19174, P43246, P84022, Q13485, P20585, P52701, Q13547, P14923, P30279, Q13489, P98170, P62873, P63218, P50151, P78417, O75293, P0DP23, Q13557, P01568, P14784, P40189, P01042

LAMA4, LAMB3, PIK3CB, HSP90AA1, HSP90AB1, STAT1, PLCG1, MSH2, SMAD3, SMAD4, MSH3, MSH6, HDAC1, JUP, CCND2, BIRC3, BIRC4, GNB1, GNG5, GNG10, GSTO1, GADD45B, CALM1, CAMK2D, IFNA21, IL2RB, IL6ST, KNG1

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P11142	HSPA8	Heat shock cognate 71 kDa protein	Q16363	LAMA4	Laminin subunit alpha-4	0.793
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	Q13751	LAMB3	Laminin subunit beta-3	0.868
P29375	JARID1A	Lysine-specific demethylase 5A	P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	-0.79
P11142	HSPA8	Heat shock cognate 71 kDa protein	P07900	HSP90AA1	Heat shock protein HSP 90-alpha	0.709
P29375	JARID1A	Lysine-specific demethylase 5A	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.711
P11142	HSPA8	Heat shock cognate 71 kDa protein	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.876
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P08238	HSP90AB1	Heat shock protein HSP 90-beta	-0.724
P29375	JARID1A	Lysine-specific demethylase 5A	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.764
P11142	HSPA8	Heat shock cognate 71 kDa protein	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.754
P11142	HSPA8	Heat shock cognate 71 kDa protein	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.936
P29375	JARID1A	Lysine-specific demethylase 5A	P43246	MSH2	DNA mismatch repair protein Msh2	0.87
P11142	HSPA8	Heat shock cognate 71 kDa protein	P43246	MSH2	DNA mismatch repair protein Msh2	0.802
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P43246	MSH2	DNA mismatch repair protein Msh2	-0.742
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P84022	SMAD3	Mothers against decapentaplegic homolog 3	0.847
O43318	MAP3K7	Mitogen-activated protein kinase kinase kinase 7	Q13485	SMAD4	Mothers against decapentaplegic homolog 4	0.794
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	Q13485	SMAD4	Mothers against decapentaplegic homolog 4	-0.899
P11142	HSPA8	Heat shock cognate 71 kDa protein	P20585	MSH3	DNA mismatch repair protein Msh3	0.715
O43318	MAP3K7	Mitogen-activated protein kinase kinase kinase 7	P52701	MSH6	DNA mismatch repair protein Msh6	0.91
P11142	HSPA8	Heat shock cognate 71 kDa protein	Q13547	HDAC1	Histone deacetylase 1	0.713
P29375	JARID1A	Lysine-specific demethylase 5A	P14923	JUP	Junction plakoglobin	-0.735
O43318	MAP3K7	Mitogen-activated protein kinase kinase kinase 7	P30279	CCND2	G1/S-specific cyclin-D2	0.704
P11142	HSPA8	Heat shock cognate 71 kDa protein	P30279	CCND2	G1/S-specific cyclin-D2	0.731
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	Q13489	BIRC3	Baculoviral IAP repeat-containing protein 3	0.715
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P98170	BIRC4	E3 ubiquitin-protein ligase XIAP	0.716
P11142	HSPA8	Heat shock cognate 71 kDa protein	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.746
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	-0.709
O43318	MAP3K7	Mitogen-activated protein kinase kinase kinase 7	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	-0.707
P11142	HSPA8	Heat shock cognate 71 kDa protein	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	-0.818
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	0.759
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P50151	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	0.744
O43318	MAP3K7	Mitogen-activated protein kinase kinase kinase 7	P78417	GSTO1	Glutathione S-transferase omega-1	-0.849
P11142	HSPA8	Heat shock cognate 71 kDa protein	P78417	GSTO1	Glutathione S-transferase omega-1	-0.715
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P78417	GSTO1	Glutathione S-transferase omega-1	0.754
P29375	JARID1A	Lysine-specific demethylase 5A	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.748
P11142	HSPA8	Heat shock cognate 71 kDa protein	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.772
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	0.708
P29375	JARID1A	Lysine-specific demethylase 5A	P0DP23	CALM1	Calmodulin-1	0.755
P11142	HSPA8	Heat shock cognate 71 kDa protein	P0DP23	CALM1	Calmodulin-1	0.804
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P0DP23	CALM1	Calmodulin-1	-0.724
P11142	HSPA8	Heat shock cognate 71 kDa protein	Q13557	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta	0.745
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P01568	IFNA21	Interferon alpha-21	0.703
P29375	JARID1A	Lysine-specific demethylase 5A	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.768
P11142	HSPA8	Heat shock cognate 71 kDa protein	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.831
P29375	JARID1A	Lysine-specific demethylase 5A	P40189	IL6ST	Interleukin-6 receptor subunit beta	0.83
P11142	HSPA8	Heat shock cognate 71 kDa protein	P01042	KNG1	Kininogen-1	-0.742
Q96KQ7	EHMT2	Histone-lysine N-methyltransferase EHMT2	P01042	KNG1	Kininogen-1	0.708

Azacitidine

hsa05202

Transcriptional misregulation in cancer

1.24E-04

Q15532, Q13315, P41732, P14780, P27930, P14923, Q15744, Q16548, Q13077, P46527, P35226, P05164, P12838, P08246, Q9C0K0, P24522

SS18, ATM, TSPAN7, MMP9, IL1R2, JUP, CEBPE, BCL2A1, TRAF1, CDKN1B, BMI1, MPO, DEFA4, ELA2, BCL11B, GADD45A

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P32320	CDA	Cytidine deaminase	Q15532	SS18	Protein SSXT	-0.722
P04183	TK1	Thymidine kinase, cytosolic	Q13315	ATM	Serine-protein kinase ATM	-0.765
P32320	CDA	Cytidine deaminase	Q13315	ATM	Serine-protein kinase ATM	-0.748
P49913	CAMP	Cathelicidin antimicrobial peptide	Q13315	ATM	Serine-protein kinase ATM	-0.775
P32320	CDA	Cytidine deaminase	P41732	TSPAN7	Tetraspanin-7	0.736
P32320	CDA	Cytidine deaminase	P14780	MMP9	Matrix metalloproteinase-9	0.951
P32320	CDA	Cytidine deaminase	P27930	IL1R2	Interleukin-1 receptor type 2	0.766
P04183	TK1	Thymidine kinase, cytosolic	P14923	JUP	Junction plakoglobin	-0.774
P04183	TK1	Thymidine kinase, cytosolic	Q15744	CEBPE	CCAAT/enhancer-binding protein epsilon	0.781
P32320	CDA	Cytidine deaminase	Q15744	CEBPE	CCAAT/enhancer-binding protein epsilon	0.761
P32320	CDA	Cytidine deaminase	Q16548	BCL2A1	Bcl-2-related protein A1	0.852
P32320	CDA	Cytidine deaminase	Q13077	TRAF1	TNF receptor-associated factor 1	-0.723
P49913	CAMP	Cathelicidin antimicrobial peptide	P46527	CDKN1B	Cyclin-dependent kinase inhibitor 1B	-0.8
P32320	CDA	Cytidine deaminase	P35226	BMI1	Polycomb complex protein BMI-1	-0.828
P49913	CAMP	Cathelicidin antimicrobial peptide	P35226	BMI1	Polycomb complex protein BMI-1	-0.723
P32320	CDA	Cytidine deaminase	P35226	BMI1	Polycomb complex protein BMI-1	-0.828
P49913	CAMP	Cathelicidin antimicrobial peptide	P35226	BMI1	Polycomb complex protein BMI-1	-0.723
P04183	TK1	Thymidine kinase, cytosolic	P05164	MPO	Myeloperoxidase	0.917
P32320	CDA	Cytidine deaminase	P05164	MPO	Myeloperoxidase	0.909
P32320	CDA	Cytidine deaminase	P12838	DEFA4	Neutrophil defensin 4	0.822
P49913	CAMP	Cathelicidin antimicrobial peptide	P12838	DEFA4	Neutrophil defensin 4	0.718
P04183	TK1	Thymidine kinase, cytosolic	P08246	ELA2	Neutrophil elastase	0.838
P32320	CDA	Cytidine deaminase	P08246	ELA2	Neutrophil elastase	0.92
P49913	CAMP	Cathelicidin antimicrobial peptide	P08246	ELA2	Neutrophil elastase	0.807
P04183	TK1	Thymidine kinase, cytosolic	Q9C0K0	BCL11B	B-cell lymphoma/leukemia 11B	-0.783
P32320	CDA	Cytidine deaminase	Q9C0K0	BCL11B	B-cell lymphoma/leukemia 11B	-0.867
P04183	TK1	Thymidine kinase, cytosolic	P24522	GADD45A	Growth arrest and DNA damage-inducible protein GADD45 alpha	0.718
P32320	CDA	Cytidine deaminase	P24522	GADD45A	Growth arrest and DNA damage-inducible protein GADD45 alpha	0.819

Azacitidine

hsa05203

Viral carcinogenesis

1.03E-04

Q08999, Q99941, P18848, P06746, P07948, P30279, P27348, P29083, Q7KZF4, P46527, Q13547, P06396, P25963, P22694, O60814

RBL2, CREBL1, ATF4, POLB, LYN, CCND2, YWHAQ, GTF2E1, SND1, CDKN1B, HDAC1, GSN, NFKBIA, PRKACB, H2BC12

Azacitidine

hsa05206

MicroRNAs in cancer

1.67E-02

P46527, Q9UM47, P35226, Q13315

CDKN1B, NOTCH3, BMI1, ATM

Azacitidine

hsa05210

Colorectal cancer

7.33E-03

P84022, Q13485, P43246, P52701, O75293

SMAD3, SMAD4, MSH2, MSH6, GADD45B

Azacitidine

hsa05212

Pancreatic cancer

1.38E-03

P42338, P42224, P84022, Q13485, O75293

PIK3CB, STAT1, SMAD3, SMAD4, GADD45B

Azacitidine

hsa05214

Glioma

7.31E-05

P0DP23, Q16566, Q13557, P42338, P19174, O75293

CALM1, CAMK4, CAMK2D, PIK3CB, PLCG1, GADD45B

Azacitidine

hsa05221

Acute myeloid leukemia

3.29E-02

P14923, Q15744, P05164

JUP, CEBPE, MPO

Azacitidine

hsa05222

Small cell lung cancer

3.80E-02

Q13751, Q13489, P98170, O75293

LAMB3, BIRC3, BIRC4, GADD45B

Azacitidine

hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

3.11E-02

O95267, P20963, P09693, O60603, P10747, Q04759, Q16539

RASGRP1, CD247, CD3G, TLR2, CD28, PRKCQ, MAPK14

Azacitidine

hsa05310

Asthma

1.68E-03

P13765, P12724, P01375

HLA-DOB, RNASE3, TNF

Azacitidine

hsa05321

Inflammatory bowel disease

2.47E-03

O60603, P01375, P13765, Q14765, Q9UL17, P23771

TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3

Azacitidine

hsa05322

Systemic lupus erythematosus

4.61E-02

O75015, P08246, P08311, P01375, P10747, P13765, Q6FI13, P05455

FCGR3B, ELA2, CTSG, TNF, CD28, HLA-DOB, H2AC18; H2AC19, SSB

Azacitidine

hsa05323

Rheumatoid arthritis

2.84E-02

P01375, P13765, P10747, P09341, O60603

TNF, HLA-DOB, CD28, CXCL1, TLR2

Azacitidine

hsa05330

Allograft rejection

4.31E-02

P10747, P01375

CD28, TNF

Azacitidine

hsa05332

Graft-versus-host disease

3.93E-03

P13765, P10747, P01375, P26715, Q13241

HLA-DOB, CD28, TNF, KLRC1, KLRD1

Azacitidine

hsa05418

Fluid shear stress and atherosclerosis

1.40E-04

Q16539, P42338, Q14145, P14598, P10599, P14780, P01375, P14778, P27930, P0DP23, P08238

MAPK14, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, IL1R1, IL1R2, CALM1, HSP90AB1

Community members of Azacitidine (S_DC: 3.82)

UniProtAC

Gene Name

Protein Name

Reported/
Predicted

S_PV

DNMT1

DNA

Reported

0.3404

0.2809

0.2659

0.998

Q96KQ7

EHMT2

HistoneNonelysine NNonemethyltransferase EHMT2

Predicted

0.0728

0.2165

0.2909

0.7603

Q15788

NCOA1

Nuclear receptor coactivator 1

Predicted

0.4368

0.0828

0.3114

0.6954

P04183

TK1

Thymidine kinase, cytosolic

Predicted

0.2717

0.1637

0.1653

0.6286

P32320

CDA

Cytidine deaminase

Predicted

0.0516

0.0569

0.1653

0.3049

P42338

PIK3CB

Phosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoform

Predicted

0.0447

0.9416

2.9055

P49841

GSK3B

Glycogen synthase kinaseNone3 beta

Predicted

0.1678

3.0839

P11142

HSPA8

Heat shock cognate 71 kDa protein

Predicted

0.9682

0.0773

0.6729

1.3115

Q53EL6

PDCD4

Programmed cell death protein 4

Predicted

0.3899

0.0653

0.3202

0.6457

P04406

GAPDH

GlyceraldehydeNone3Nonephosphate dehydrogenase

Predicted

0.4535

0.1223

0.4666

0.938

P20839

IMPDH1

InosineNone5'Nonemonophosphate dehydrogenase 1

Predicted

0.1928

0.1307

0.1653

0.5231

O43318

MAP3K7

MitogenNoneactivated protein kinase kinase kinase 7

Predicted

0.0059

0.3649

1.7327

P29375

JARID1A

LysineNonespecific demethylase 5A

Predicted

0.3605

0.7052

1.5906

P49913

CAMP

Cathelicidin antimicrobial peptide

Predicted

0.3356

0.0407

0.5275

0.7766

PharmaCoNets of Azacitidine (SPCN: 72.63 )

Azacitidine regulated-network (SDN: 19.01)

Community members of Azacitidine (SDC: 3.82)

PharmaCoNets of Azacitidine (S_PCN: 72.63 )

Azacitidine regulated-network (S_DN: 19.01)

Community members of Azacitidine (S_DC: 3.82)