PharmaCoNets of Yohimbine (SPCN: 104.40 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Yohimbinehsa00030Pentose phosphate pathway1.08E-053P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Yohimbinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Yohimbinehsa00071Fatty acid degradation2.52E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Yohimbinehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Yohimbinehsa00500Starch and sucrose metabolism1.85E-063O43451, P46976, P06737MGAM, GYG1, PYGLMore
Yohimbinehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Yohimbinehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Yohimbinehsa00630Glyoxylate and dicarboxylate metabolism4.12E-032P40925, P15104MDH1, GLULMore
Yohimbinehsa00730Thiamine metabolism1.12E-063Q9Y6K8, P05186, P24666AK5, ALPL, ACP1More
Yohimbinehsa00760Nicotinate and nicotinamide metabolism3.52E-021P21589NT5EMore
Yohimbinehsa00770Pantothenate and CoA biosynthesis5.15E-043O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Yohimbinehsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Yohimbinehsa00970Aminoacyl-tRNA biosynthesis2.77E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Yohimbinehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Yohimbinehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Yohimbinehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Yohimbinehsa01100Metabolic pathways5.18E-0329Q9NR34, P05089, O95455, P21953, P32320, P22748, P11766, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, Q08477, P15907, P57054, Q9UNP4, Q9BX95, P37837, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737MAN1C1, ARG1, TGDS, BCKDHB, CDA, CA4, ADH5, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, CYP4F3, ST6GAL1, PIGP, ST3GAL5, SGPP1, TALDO1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGLMore
Yohimbinehsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Yohimbinehsa01230Biosynthesis of amino acids2.22E-034P51854, P60891, Q99707, P37837TKTL1, PRPS1, MTR, TALDO1More
Yohimbinehsa02010ABC transporters2.29E-022P45844, P08183ABCG1, ABCB1More
Yohimbinehsa03008Ribosome biogenesis in eukaryotes1.88E-023O14980, O60832, Q9BVP2XPO1, DKC1, GNL3More
Yohimbinehsa03013RNA transport2.35E-0510O14980, P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, Q14240, P23588, Q9Y6A5XPO1, NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF4A2, EIF4B, TACC3More
Yohimbinehsa03020RNA polymerase3.00E-023P30876, P24928, P62487POLR2B, POLR2A, POLR2GMore
Yohimbinehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Yohimbinehsa03060Protein export4.42E-022P37108, Q15005SRP14, SPCS2More
Yohimbinehsa04012ErbB signaling pathway3.15E-023P16333, P19174, P01106NCK1, PLCG1, MYCMore
Yohimbinehsa04060Cytokine-cytokine receptor interaction4.71E-022P78552, O75509IL13RA1, TNFRSF21More
Yohimbinehsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, P25025, P14784CXCL1, CXCL2, CXCR1, CXCR2, IL2RBMore
Yohimbinehsa04062Chemokine signaling pathway1.83E-028P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10More
Yohimbinehsa04064NF-kappa B signaling pathway1.14E-0520Q13489, O00463, Q13546, P14778, P01584, P19174, Q04759, Q9UDY8, Q13077, Q16548, P06239, Q8WV28, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9UNE0, Q9NQC7BIRC3, TRAF5, RIPK1, IL1R1, IL1B, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LCK, BLNK, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, EDAR, CYLDMore
Yohimbinehsa04070Phosphatidylinositol signaling system1.53E-022Q86XP1, Q96DU7DGKH, ITPKCMore
Yohimbinehsa04071Sphingolipid signaling pathway6.08E-045P21453, Q9H228, P01375, Q13362, Q9UQC2S1PR1, EDG8, TNF, PPP2R5C, GAB2More
Yohimbinehsa04072Phospholipase D signaling pathway5.17E-037P42338, Q92529, P43657, P25024, P25025, P19174, Q14344PIK3CB, SHC3, P2RY5, CXCR1, CXCR2, PLCG1, GNA13More
Yohimbinehsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Yohimbinehsa04110Cell cycle1.44E-027P06493, O75293, P30304, P33981, P42773, P01106, Q13547CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYC, HDAC1More
Yohimbinehsa04114Oocyte meiosis1.33E-024P51812, Q02750, P16298, Q17RY0RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Yohimbinehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Yohimbinehsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Yohimbinehsa04142Lysosome1.46E-027P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2More
Yohimbinehsa04144Endocytosis1.67E-028P0DMV8, Q9H444, O75351, P62491, Q96B97, Q15438, Q14161, Q9UMY4HSPA1A, CHMP4B, VPS4B, RAB11A, SH3KBP1, PSCD1, GIT2, SNX12More
Yohimbinehsa04150mTOR signaling pathway2.23E-036P42338, Q02750, Q9NQL2, P51812, Q13322, P49841PIK3CB, MAP2K1, RRAGD, RPS6KA3, GRB10, GSK3BMore
Yohimbinehsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Yohimbinehsa04211Longevity regulating pathway1.18E-023Q12778, Q9UEF7, Q96KQ7FOXO1, KL, EHMT2More
Yohimbinehsa04213Longevity regulating pathway - multiple species2.70E-037P42338, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547PIK3CB, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Yohimbinehsa04217Necroptosis1.85E-037P01375, P01568, P48023, Q13489, Q13546, Q14765, Q99878TNF, IFNA21, FASLG, BIRC3, RIPK1, STAT4, H2AC14More
Yohimbinehsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Yohimbinehsa04270Vascular smooth muscle contraction6.96E-036P0DP23, Q08828, P51828, P35579, P35749, P35318CALM1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Yohimbinehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Yohimbinehsa04370VEGF signaling pathway2.68E-033P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Yohimbinehsa04380Osteoclast differentiation4.80E-024P06239, P42338, P14778, Q8N149LCK, PIK3CB, IL1R1, LILRA2More
Yohimbinehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Yohimbinehsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Yohimbinehsa04613Neutrophil extracellular trap formation2.18E-037P04908, Q93077, P62807, O60814, P68431, O43315, Q16539H2AC4; H2AC8, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, AQP9, MAPK14More
Yohimbinehsa04620Toll-like receptor signaling pathway4.16E-022Q13546, P01568RIPK1, IFNA21More
Yohimbinehsa04621NOD-like receptor signaling pathway3.36E-0311Q16539, P01568, Q13489, P10599, Q9H1Y0, P43490, O00463, Q13546, P01375, P09341, P12838MAPK14, IFNA21, BIRC3, TXN, ATG5, PBEF1, TRAF5, RIPK1, TNF, CXCL1, DEFA4More
Yohimbinehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Yohimbinehsa04623Cytosolic DNA-sensing pathway9.06E-054P01584, P01568, Q13546, Q8NHW4IL1B, IFNA21, RIPK1, CCL4L2More
Yohimbinehsa04640Hematopoietic cell lineage1.37E-027P14778, P27930, P11215, P25063, P07766, P01732, P09564IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD7More
Yohimbinehsa04650Natural killer cell mediated cytotoxicity3.09E-0715P16298, P50591, P19174, P01375, P06239, O60880, P20963, P42338, Q02750, Q13241, P26718, O14931, P26717, Q14953, P26715PPP3CB, TNFSF10, PLCG1, TNF, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, KLRD1, KLRK1, NCR3, KLRC2, KIR2DS5, KLRC1More
Yohimbinehsa04657IL-17 signaling pathway1.35E-058O00463, Q16539, P49841, P09341, P19875, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, LCN2, TNFMore
Yohimbinehsa04658Th1 and Th2 cell differentiation1.47E-0710Q04759, P07766, P20963, P19174, P01730, P06239, P42224, Q9UL17, P14784, Q13761PRKCQ, CD3E, CD247, PLCG1, CD4, LCK, STAT1, TBX21, IL2RB, RUNX3More
Yohimbinehsa04659Th17 cell differentiation3.11E-0610Q04759, P19174, P01730, P06239, P42224, P14784, P14778, Q9UL17, P07766, P20963PRKCQ, PLCG1, CD4, LCK, STAT1, IL2RB, IL1R1, TBX21, CD3E, CD247More
Yohimbinehsa04660T cell receptor signaling pathway4.50E-0410Q04759, P42338, P19174, P16333, P07766, P20963, P01730, P01732, Q13191, P06239PRKCQ, PIK3CB, PLCG1, NCK1, CD3E, CD247, CD4, CD8A, CBLB, LCKMore
Yohimbinehsa04662B cell receptor signaling pathway7.25E-034P49841, P42338, P21854, Q8N149GSK3B, PIK3CB, CD72, LILRA2More
Yohimbinehsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Yohimbinehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Yohimbinehsa04720Long-term potentiation1.38E-023P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Yohimbinehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Yohimbinehsa04730Long-term depression3.52E-021Q14344GNA13More
Yohimbinehsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Yohimbinehsa04742Taste transduction1.01E-021P30939HTR1FMore
Yohimbinehsa04750Inflammatory mediator regulation of TRP channels8.33E-059P14778, P01584, Q08828, P51828, P19174, P42338, P24723, Q04759, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PLCG1, PIK3CB, PRKCH, PRKCQ, CALM1More
Yohimbinehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Yohimbinehsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Yohimbinehsa04914Progesterone-mediated oocyte maturation2.94E-023Q17RY0, P51812, Q02750CPEB4, RPS6KA3, MAP2K1More
Yohimbinehsa04915Estrogen signaling pathway3.17E-025Q08828, P51828, P0DMV8, P0DP23, Q15788ADCY1, ADCY7, HSPA1A, CALM1, NCOA1More
Yohimbinehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Yohimbinehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Yohimbinehsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Yohimbinehsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Yohimbinehsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Yohimbinehsa04929GnRH secretion3.63E-022P42338, P49407PIK3CB, ARRB1More
Yohimbinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Yohimbinehsa04932Non-alcoholic fatty liver disease7.01E-0511P01375, P49841, O43521, P48023, O75460, P01584, P13073, P12074, Q16718, O95298, O14521TNF, GSK3B, BCL2L11, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA5, NDUFC2, SDHDMore
Yohimbinehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Yohimbinehsa04960Aldosterone-regulated sodium reabsorption4.38E-021P48048KCNJ1More
Yohimbinehsa04970Salivary secretion2.43E-036P07550, Q08828, P51828, P22694, P0DP23, P49913ADRB2, ADCY1, ADCY7, PRKACB, CALM1, CAMPMore
Yohimbinehsa04973Carbohydrate digestion and absorption6.19E-052O43451, P42338MGAM, PIK3CBMore
Yohimbinehsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Yohimbinehsa04976Bile secretion1.90E-046O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Yohimbinehsa05016Huntington disease2.46E-029O95298, P13073, P12074, P24928, P30876, P62487, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, ERN1, PSMB4, PSMD12More
Yohimbinehsa05020Prion disease3.80E-024Q16718, O14521, P49841, Q16539NDUFA5, SDHD, GSK3B, MAPK14More
Yohimbinehsa05022Pathways of neurodegeneration - multiple diseases1.24E-026P49841, Q16718, O14521, Q13561, Q16539, Q08752GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPIDMore
Yohimbinehsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Yohimbinehsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Yohimbinehsa05120Epithelial cell signaling in Helicobacter pylori infection1.29E-056Q16539, P09341, P19875, P19174, P25024, P25025MAPK14, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Yohimbinehsa05132Salmonella infection9.85E-034Q13546, Q13489, O60282, P68371RIPK1, BIRC3, KIF5C, TUBB2CMore
Yohimbinehsa05134Legionellosis8.80E-047P01584, Q9NR31, P11215, P0DMV8, P11142, P09341, P19875IL1B, SAR1A, ITGAM, HSPA1A, HSPA8, CXCL1, CXCL2More
Yohimbinehsa05140Leishmaniasis1.77E-037P13612, O75015, P13765, O60603, P01375, P49006, Q16539ITGA4, FCGR3B, HLA-DOB, TLR2, TNF, MARCKSL1, MAPK14More
Yohimbinehsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Yohimbinehsa05144Malaria1.91E-023P01375, P35443, P26718TNF, THBS4, KLRK1More
Yohimbinehsa05146Amoebiasis7.68E-0712P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P30679, P22694, P12814CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1More
Yohimbinehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Yohimbinehsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Yohimbinehsa05163Human cytomegalovirus infection3.58E-0416P01375, P50151, Q14643, P0DP23, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, P04637, O00463TNF, GNG10, ITPR1, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, TP53, TRAF5More
Yohimbinehsa05167Kaposi sarcoma-associated herpesvirus infection1.94E-024P62879, P16298, Q02750, P0CG47GNB2, PPP3CB, MAP2K1, UBBMore
Yohimbinehsa05170Human immunodeficiency virus 1 infection6.02E-035Q02750, P62879, P16298, Q05397, P20333MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1BMore
Yohimbinehsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Yohimbinehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Yohimbinehsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Yohimbinehsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Yohimbinehsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Yohimbinehsa05223Non-small cell lung cancer4.24E-023P19174, Q9HC35, O75293PLCG1, EML4, GADD45BMore
Yohimbinehsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Yohimbinehsa05225Hepatocellular carcinoma1.85E-022Q92529, P51531SHC3, SMARCA2More
Yohimbinehsa05226Gastric cancer3.79E-022Q02750, O15169MAP2K1, AXIN1More
Yohimbinehsa05231Choline metabolism in cancer4.24E-023Q9Y259, P19174, P49619CHKB, PLCG1, DGKGMore
Yohimbinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer8.76E-0613P42338, O95267, P19174, P07766, P20963, P09693, P06239, P42224, O60603, Q04759, Q16539, Q9HC35, P01730PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, STAT1, TLR2, PRKCQ, MAPK14, EML4, CD4More
Yohimbinehsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Yohimbinehsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Yohimbinehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Yohimbinehsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Yohimbinehsa05340Primary immunodeficiency4.24E-023P01730, P07766, P06239CD4, CD3E, LCKMore
Yohimbinehsa05415Diabetic cardiomyopathy1.28E-024Q16718, O14521, Q16539, P49841NDUFA5, SDHD, MAPK14, GSK3BMore
Yohimbinehsa05418Fluid shear stress and atherosclerosis2.04E-048Q16539, P42338, P10599, P14780, P01375, P04637, P14778, P27930MAPK14, PIK3CB, TXN, MMP9, TNF, TP53, IL1R1, IL1R2More

Community members of Yohimbine (SDC: 6.95)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P14416DRD2D(2) dopamine receptorReported00.060410.47792.5081
P48048KCNJ1ATPNonesensitive inward rectifier potassium channel 1Reported00.00420.2820.12740.6935
P78508KCNJ10ATPNonesensitive inward rectifier potassium channel 10Reported00.07310.08780.20670.4189
Q99712KCNJ15ATPNonesensitive inward rectifier potassium channel 15Reported00.15870.07790.12670.3619
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P30304CDC25AMNonephase inducer phosphatase 1Predicted00.17950.23470.42740.9865
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
P11511CYP19A1AromatasePredicted00.815610.15882.5666
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
DRD2P14416Ki280
DRD2P14416Ki398.1