PharmaCoNets of Tubocurarine (SPCN: 20.07 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Tubocurarinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Tubocurarinehsa00220Arginine biosynthesis4.88E-021P49448GLUD2More
Tubocurarinehsa00250Alanine, aspartate and glutamate metabolism4.88E-021P49448GLUD2More
Tubocurarinehsa00471D-Glutamine and D-glutamate metabolism1.65E-021P49448GLUD2More
Tubocurarinehsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Tubocurarinehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Tubocurarinehsa00830Retinol metabolism3.49E-021P00325ADH1BMore
Tubocurarinehsa00910Nitrogen metabolism4.88E-021P49448GLUD2More
Tubocurarinehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Tubocurarinehsa01522Endocrine resistance4.96E-023Q16539, P04637, P10415MAPK14, TP53, BCL2More
Tubocurarinehsa03008Ribosome biogenesis in eukaryotes1.56E-023Q9NYH9, P78345, O15381UTP6, RPP38, NVLMore
Tubocurarinehsa03060Protein export3.28E-021Q15070OXA1LMore
Tubocurarinehsa04014Ras signaling pathway4.65E-023Q15311, P0DP23, P17612RALBP1, CALM1, PRKACAMore
Tubocurarinehsa04061Viral protein interaction with cytokine and cytokine receptor1.12E-0310P51684, P32248, P09341, P19875, P25024, P02775, P25025, P47992, Q9UBD3, P14784CCR6, CCR7, CXCL1, CXCL2, CXCR1, PPBP, CXCR2, XCL1, XCL2, IL2RBMore
Tubocurarinehsa04062Chemokine signaling pathway1.83E-028P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10More
Tubocurarinehsa04064NF-kappa B signaling pathway2.15E-027P14778, P19174, Q04759, P06239, P09341, P19875, Q06643IL1R1, PLCG1, PRKCQ, LCK, CXCL1, CXCL2, LTBMore
Tubocurarinehsa04071Sphingolipid signaling pathway1.94E-023Q9H228, P01375, Q9UQC2EDG8, TNF, GAB2More
Tubocurarinehsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Tubocurarinehsa04114Oocyte meiosis2.15E-023P0DP23, P17612, Q13362CALM1, PRKACA, PPP2R5CMore
Tubocurarinehsa04144Endocytosis4.07E-035Q9H444, O75351, P42566, Q15438, Q14161CHMP4B, VPS4B, EPS15, PSCD1, GIT2More
Tubocurarinehsa04152AMPK signaling pathway2.34E-022Q96EB6, P36956SIRT1, SREBF1More
Tubocurarinehsa04210Apoptosis1.73E-0310P04637, P10415, O76075, P01375, Q9NR28, P24522, Q16548, Q13077, P43234, Q14643TP53, BCL2, DFFB, TNF, DIABLO, GADD45A, BCL2A1, TRAF1, CTSO, ITPR1More
Tubocurarinehsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Tubocurarinehsa04217Necroptosis4.56E-034P23458, Q9NQC7, Q9H444, O75351JAK1, CYLD, CHMP4B, VPS4BMore
Tubocurarinehsa04261Adrenergic signaling in cardiomyocytes2.50E-023P17612, Q13362, P0DP23PRKACA, PPP2R5C, CALM1More
Tubocurarinehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Tubocurarinehsa04640Hematopoietic cell lineage1.37E-027P14778, P27930, P11215, P25063, P07766, P01732, P09564IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD7More
Tubocurarinehsa04650Natural killer cell mediated cytotoxicity2.48E-038P19174, P06239, O60880, P20963, P42338, Q13241, P26718, O14931PLCG1, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3More
Tubocurarinehsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Tubocurarinehsa04658Th1 and Th2 cell differentiation2.55E-0512Q04759, P07766, P20963, P09693, Q16539, P19174, P06239, P23771, Q9UL17, P14784, P13765, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, LCK, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Tubocurarinehsa04659Th17 cell differentiation1.25E-038Q04759, P19174, P06239, P14784, P14778, Q9UL17, P07766, P20963PRKCQ, PLCG1, LCK, IL2RB, IL1R1, TBX21, CD3E, CD247More
Tubocurarinehsa04660T cell receptor signaling pathway3.37E-038Q04759, P42338, P19174, P07766, P20963, P01732, Q13191, P06239PRKCQ, PIK3CB, PLCG1, CD3E, CD247, CD8A, CBLB, LCKMore
Tubocurarinehsa04713Circadian entrainment4.42E-022P0DP23, P17612CALM1, PRKACAMore
Tubocurarinehsa04720Long-term potentiation4.42E-022P0DP23, P17612CALM1, PRKACAMore
Tubocurarinehsa04722Neurotrophin signaling pathway2.34E-024Q16566, P04637, Q16539, P10415CAMK4, TP53, MAPK14, BCL2More
Tubocurarinehsa04725Cholinergic synapse3.92E-023Q14643, Q16566, P10415ITPR1, CAMK4, BCL2More
Tubocurarinehsa04728Dopaminergic synapse1.55E-023P17612, Q13362, P0DP23PRKACA, PPP2R5C, CALM1More
Tubocurarinehsa04740Olfactory transduction6.71E-032P0DP23, P17612CALM1, PRKACAMore
Tubocurarinehsa04750Inflammatory mediator regulation of TRP channels7.24E-035P14778, P19174, P42338, P24723, Q04759IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQMore
Tubocurarinehsa04910Insulin signaling pathway1.91E-035P0DP23, P17612, P22694, P06737, P49841CALM1, PRKACA, PRKACB, PYGL, GSK3BMore
Tubocurarinehsa04916Melanogenesis2.87E-022P17612, P0DP23PRKACA, CALM1More
Tubocurarinehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Tubocurarinehsa04921Oxytocin signaling pathway1.84E-023P0DP23, P17612, Q96RR4CALM1, PRKACA, CAMKK2More
Tubocurarinehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Tubocurarinehsa04924Renin secretion1.09E-022P17612, P0DP23PRKACA, CALM1More
Tubocurarinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Tubocurarinehsa04964Proximal tubule bicarbonate reclamation4.88E-021P49448GLUD2More
Tubocurarinehsa04970Salivary secretion2.20E-022P17612, P0DP23PRKACA, CALM1More
Tubocurarinehsa04971Gastric acid secretion2.87E-022P17612, P0DP23PRKACA, CALM1More
Tubocurarinehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Tubocurarinehsa04976Bile secretion1.19E-034P17612, P22694, P08183, Q14032PRKACA, PRKACB, ABCB1, BAATMore
Tubocurarinehsa05031Amphetamine addiction2.87E-022P0DP23, P17612CALM1, PRKACAMore
Tubocurarinehsa05034Alcoholism1.29E-023P17612, P0DP23, Q96RR4PRKACA, CALM1, CAMKK2More
Tubocurarinehsa05120Epithelial cell signaling in Helicobacter pylori infection2.78E-035P09341, P19875, P19174, P25024, P25025CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Tubocurarinehsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Tubocurarinehsa05146Amoebiasis2.21E-048P09341, P19875, P14778, P27930, P42338, P11215, P05089, P12814CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, ACTN1More
Tubocurarinehsa05169Epstein-Barr virus infection3.45E-026P13765, P04637, P10415, Q16539, P24522, P09693HLA-DOB, TP53, BCL2, MAPK14, GADD45A, CD3GMore
Tubocurarinehsa05202Transcriptional misregulation in cancer2.62E-027Q15532, P14923, Q13077, O15550, P04637, P05164, P24522SS18, JUP, TRAF1, UTX, TP53, MPO, GADD45AMore
Tubocurarinehsa05210Colorectal cancer2.89E-024P10415, P04637, Q9UJU2, P24522BCL2, TP53, LEF1, GADD45AMore
Tubocurarinehsa05212Pancreatic cancer2.87E-022Q15311, P23458RALBP1, JAK1More
Tubocurarinehsa05213Endometrial cancer2.21E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Tubocurarinehsa05214Glioma2.21E-023Q16566, P04637, P24522CAMK4, TP53, GADD45AMore
Tubocurarinehsa05216Thyroid cancer6.17E-033Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Tubocurarinehsa05217Basal cell carcinoma1.56E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Tubocurarinehsa05221Acute myeloid leukemia3.00E-023P14923, Q9UJU2, P05164JUP, LEF1, MPOMore
Tubocurarinehsa05222Small cell lung cancer2.34E-024P10415, Q13077, P04637, P24522BCL2, TRAF1, TP53, GADD45AMore
Tubocurarinehsa05224Breast cancer4.96E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Tubocurarinehsa05226Gastric cancer1.12E-025Q9UJU2, P04637, P24522, P14923, P10415LEF1, TP53, GADD45A, JUP, BCL2More
Tubocurarinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer8.27E-036P42338, P19174, P07766, P20963, P06239, Q04759PIK3CB, PLCG1, CD3E, CD247, LCK, PRKCQMore

Community members of Tubocurarine (SDC: 2.43)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q9HB89NMUR1NeuromedinNoneU receptor 1Predicted00.00240.30300.6072
P23025XPADNA repair protein complementing XPNoneA cellsPredicted00.00510.02320.20320.2521
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
Q8NFZ4NLGN2NeuroliginNone2Predicted00.5660.06920.16270.5841
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)