PharmaCoNets of Triazolam (SPCN: 256.29 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Triazolamhsa00020Citrate cycle (TCA cycle)2.78E-022O75390, P40926CS, MDH2More
Triazolamhsa00040Pentose and glucuronate interconversions3.53E-021O60701UGDHMore
Triazolamhsa00052Galactose metabolism1.06E-032P06280, O43451GLA, MGAMMore
Triazolamhsa00071Fatty acid degradation4.66E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Triazolamhsa00190Oxidative phosphorylation8.71E-033Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Triazolamhsa00220Arginine biosynthesis5.61E-053P15104, P05089, P49448GLUL, ARG1, GLUD2More
Triazolamhsa00230Purine metabolism4.02E-022P31350, P21589RRM2, NT5EMore
Triazolamhsa00240Pyrimidine metabolism2.54E-043P31350, P21589, P04818RRM2, NT5E, TYMSMore
Triazolamhsa00310Lysine degradation1.85E-045Q96KQ7, Q8NEZ4, Q13029, Q02809, P51648EHMT2, MLL3, PRDM2, PLOD1, ALDH3A2More
Triazolamhsa00340Histidine metabolism4.52E-021O95954FTCDMore
Triazolamhsa00380Tryptophan metabolism4.14E-021Q16613AANATMore
Triazolamhsa00500Starch and sucrose metabolism7.12E-073O43451, P46976, P06737MGAM, GYG1, PYGLMore
Triazolamhsa00512Mucin type O-glycan biosynthesis3.19E-033O95395, Q8N4A0, Q9NY28GCNT3, GALNT4, GALNT8More
Triazolamhsa00520Amino sugar and nucleotide sugar metabolism1.57E-023Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Triazolamhsa00531Glycosaminoglycan degradation1.05E-032P15586, P34059GNS, GALNSMore
Triazolamhsa00532Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate3.30E-021Q9Y2C2USTMore
Triazolamhsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.91E-021Q9NY97B3GNT2More
Triazolamhsa00564Glycerophospholipid metabolism8.90E-054Q9Y259, P23743, P49619, Q3LIE5CHKB, DGKA, DGKG, ADPRMMore
Triazolamhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Triazolamhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Triazolamhsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Triazolamhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series7.02E-032P06865, O75752HEXA, B3GALNT1More
Triazolamhsa00630Glyoxylate and dicarboxylate metabolism1.20E-053P40925, P40926, P15104MDH1, MDH2, GLULMore
Triazolamhsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Triazolamhsa00730Thiamine metabolism2.39E-052P05186, P24666ALPL, ACP1More
Triazolamhsa00740Riboflavin metabolism4.77E-021P30043BLVRBMore
Triazolamhsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Triazolamhsa00830Retinol metabolism3.93E-023P00352, Q9BPW9, O75911ALDH1A1, DHRS9, DHRS3More
Triazolamhsa00860Porphyrin and chlorophyll metabolism4.14E-021P53004BLVRAMore
Triazolamhsa00970Aminoacyl-tRNA biosynthesis6.28E-043O95363, P14868, Q15046FARS2, DARS, KARSMore
Triazolamhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Triazolamhsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Triazolamhsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Triazolamhsa01100Metabolic pathways6.99E-0330Q9NR34, Q9Y259, P05089, P32320, Q13956, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, P49619, O95954, Q9HCC0, P33121, Q02318, P57054, Q9UBX8, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P35573, P06737MAN1C1, CHKB, ARG1, CDA, PDE6H, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, DGKG, FTCD, MCCC2, ACSL1, CYP27A1, PIGP, B4GALT6, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, AGL, PYGLMore
Triazolamhsa012102-Oxocarboxylic acid metabolism1.91E-021P50213IDH3AMore
Triazolamhsa01240Biosynthesis of cofactors2.05E-022P36551, O60701CPOX, UGDHMore
Triazolamhsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Triazolamhsa01522Endocrine resistance2.16E-021P04049RAF1More
Triazolamhsa01523Antifolate resistance4.70E-045P41439, P41440, Q92820, P04818, P01375FOLR3, SLC19A1, GGH, TYMS, TNFMore
Triazolamhsa03008Ribosome biogenesis in eukaryotes4.94E-022P19784, P67870CSNK2A2, CSNK2BMore
Triazolamhsa03010Ribosome9.02E-0712P62753, P62906, P62829, P46776, Q07020, P62888, P61927, P61513, P36578, P27635, P62249, P23396RPS6, RPL10A, RPL23, RPL27A, RPL18, RPL30, RPL37, RPL37A, RPL4, RPL10, RPS16, RPS3More
Triazolamhsa03013RNA transport1.12E-0412P62826, O14893, Q15287, Q9UBU9, P63279, P68104, Q13310, P20042, Q14240, Q9BZI7, Q14232, Q06787RAN, GEMIN2, RNPS1, NXF1, UBE2I, EEF1A1, PABPC4, EIF2S2, EIF4A2, UPF3B, EIF2B1, FMR1More
Triazolamhsa03015mRNA surveillance pathway5.50E-036Q9BZI7, Q13310, Q13362, O94913, Q15287, Q9UBU9UPF3B, PABPC4, PPP2R5C, PCF11, RNPS1, NXF1More
Triazolamhsa03020RNA polymerase5.38E-084P30876, P24928, P62487, Q9Y535POLR2B, POLR2A, POLR2G, POLR3HMore
Triazolamhsa03040Spliceosome1.54E-1119Q14562, O43143, O60508, P17844, P08579, P26368, O75940, P51991, P61978, O75494, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, DDX5, SNRPB2, U2AF2, SMNDC1, HNRPA3, HNRPK, FUSIP1, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Triazolamhsa03050Proteasome9.50E-041P55036PSMD4More
Triazolamhsa03060Protein export2.33E-042P37108, Q15005SRP14, SPCS2More
Triazolamhsa03320PPAR signaling pathway1.62E-022Q13133, Q02318NR1H3, CYP27A1More
Triazolamhsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Triazolamhsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Triazolamhsa04014Ras signaling pathway4.81E-0513P04049, P42338, P20827, Q9NRA1, P49767, Q13009, P17252, Q7LDG7, P0DP23, P62873, P63218, P50151, P19174RAF1, PIK3CB, EFNA1, PDGFC, VEGFC, TIAM1, PRKCA, RASGRP2, CALM1, GNB1, GNG5, GNG10, PLCG1More
Triazolamhsa04015Rap1 signaling pathway5.57E-0411P04049, P20827, P49767, Q96FS4, P11215, Q13009, Q7LDG7, P42338, P0DP23, P17252, P19174RAF1, EFNA1, VEGFC, SIPA1, ITGAM, TIAM1, RASGRP2, PIK3CB, CALM1, PRKCA, PLCG1More
Triazolamhsa04020Calcium signaling pathway1.06E-0411P27987, Q96DU7, Q08828, Q13557, P17252, P19174, P61073, P0DP23, P05141, P51828, P49767ITPKB, ITPKC, ADCY1, CAMK2D, PRKCA, PLCG1, CXCR4, CALM1, SLC25A5, ADCY7, VEGFCMore
Triazolamhsa04022cGMP-PKG signaling pathway1.04E-049P04049, P18848, Q8WYR1, P31751, Q08828, P51828, P05141, P0DP24, P0DP23RAF1, ATF4, PIK3R5, AKT2, ADCY1, ADCY7, SLC25A5, CALM2, CALM1More
Triazolamhsa04024cAMP signaling pathway9.30E-048P63092, Q08828, P51828, P31751, P26678, P0DP23, P04049, P61586GNAS, ADCY1, ADCY7, AKT2, PLN, CALM1, RAF1, RHOAMore
Triazolamhsa04060Cytokine-cytokine receptor interaction8.46E-0414P14784, P27930, P14778, P37173, P26842, Q06643, Q13651, P78552, P25024, Q9UBD3, P47992, P09341, P80075, P01730IL2RB, IL1R2, IL1R1, TGFBR2, CD27, LTB, IL10RA, IL13RA1, CXCR1, XCL2, XCL1, CXCL1, CCL8, CD4More
Triazolamhsa04061Viral protein interaction with cytokine and cytokine receptor1.05E-048Q8NHW4, P09341, P25024, P61073, P47992, Q9UBD3, Q13651, P14784CCL4L2, CXCL1, CXCR1, CXCR4, XCL1, XCL2, IL10RA, IL2RBMore
Triazolamhsa04062Chemokine signaling pathway8.06E-0720P25024, P09341, P47992, Q9UBD3, P09769, P07948, P42338, P19174, P62873, P63218, P50151, P43250, Q08881, Q7LDG7, Q13009, P14598, P42224, P04049, P25963, Q8WYR1CXCR1, CXCL1, XCL1, XCL2, FGR, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ITK, RASGRP2, TIAM1, NCF1, STAT1, RAF1, NFKBIA, PIK3R5More
Triazolamhsa04064NF-kappa B signaling pathway4.09E-0921P10415, Q13489, O00463, P14778, P01584, P29965, Q04759, Q9UDY8, Q13077, P67870, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, Q06643, Q9NQC7BCL2, BIRC3, TRAF5, IL1R1, IL1B, CD40LG, PRKCQ, MALT1, TRAF1, CSNK2B, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, LTB, CYLDMore
Triazolamhsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Triazolamhsa04070Phosphatidylinositol signaling system2.91E-0812P19174, P0DP23, Q14643, O14986, P23743, P49619, Q86XP1, Q16760, P48426, P27987, Q96DU7, P17252PLCG1, CALM1, ITPR1, PIP5K1B, DGKA, DGKG, DGKH, DGKD, PIP4K2A, ITPKB, ITPKC, PRKCAMore
Triazolamhsa04071Sphingolipid signaling pathway1.05E-038P04049, P17252, Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2RAF1, PRKCA, EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2More
Triazolamhsa04072Phospholipase D signaling pathway4.94E-059P04049, P31751, P61586, O14986, Q15438, P63092, Q08828, P51828, Q16760RAF1, AKT2, RHOA, PIP5K1B, PSCD1, GNAS, ADCY1, ADCY7, DGKDMore
Triazolamhsa04110Cell cycle1.83E-034Q9UBD5, P06493, O60566, P33981ORC3, CDK1, BUB1B, TTKMore
Triazolamhsa04114Oocyte meiosis2.02E-0612Q9Y6D9, P51812, Q02750, Q13557, P0DP23, P16298, Q17RY0, Q08828, P51828, P27348, Q13362, Q14738MAD1L1, RPS6KA3, MAP2K1, CAMK2D, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, YWHAQ, PPP2R5C, PPP2R5DMore
Triazolamhsa04115p53 signaling pathway3.34E-022P31350, P06493RRM2, CDK1More
Triazolamhsa04120Ubiquitin mediated proteolysis7.08E-046Q14145, Q13042, Q13191, P62837, Q15751, Q7Z6Z7KEAP1, CDC16, CBLB, UBE2D2, HERC1, HUWE1More
Triazolamhsa04137Mitophagy - animal2.52E-022P19784, P67870CSNK2A2, CSNK2BMore
Triazolamhsa04140Autophagy - animal4.41E-036P31751, P04049, Q7L523, O75460, Q96GC9, Q8TEV9AKT2, RAF1, RRAGA, ERN1, TMEM49, SMCR8More
Triazolamhsa04141Protein processing in endoplasmic reticulum3.12E-0513P18848, P30101, Q15437, Q15436, P60604, Q99941, P11142, P07900, P08238, Q9NR31, P14625, Q9H173, Q9UNL2ATF4, PDIA3, SEC23B, SEC23A, UBE2G2, CREBL1, HSPA8, HSP90AA1, HSP90AB1, SAR1A, HSP90B1, SIL1, SSR3More
Triazolamhsa04142Lysosome3.96E-0613P43234, P06865, P15586, P22304, P34059, P38571, Q13510, P07602, Q9NRA2, P49281, P61916, Q04900, Q9Y227CTSO, HEXA, GNS, IDS, GALNS, LIPA, ASAH1, PSAP, SLC17A5, SLC11A2, NPC2, CD164, ENTPD4More
Triazolamhsa04144Endocytosis1.78E-0511P0DMV8, Q9H444, O75351, P62491, P42566, Q96B97, Q15438, Q14161, Q96QK1, Q9UMY4, Q9UNH7HSPA1A, CHMP4B, VPS4B, RAB11A, EPS15, SH3KBP1, PSCD1, GIT2, VPS35, SNX12, SNX6More
Triazolamhsa04145Phagosome3.28E-059P11215, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, O60603, P13765ITGAM, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, TLR2, HLA-DOBMore
Triazolamhsa04150mTOR signaling pathway7.74E-034P04049, Q02750, Q9NQL2, P51812RAF1, MAP2K1, RRAGD, RPS6KA3More
Triazolamhsa04151PI3K-Akt signaling pathway1.94E-0733P62753, P42338, P43657, P25116, O43521, P27348, P20827, P49767, Q13362, P07900, P08238, P14625, Q8WYR1, P62873, P63218, P50151, P16144, O15335, P02452, P24821, Q16363, Q13751, P22105, O60603, P14784, P01568, Q99941, P18848, P10415, P17252, O00141, Q6ZUJ8, P30281RPS6, PIK3CB, P2RY5, F2R, BCL2L11, YWHAQ, EFNA1, VEGFC, PPP2R5C, HSP90AA1, HSP90AB1, HSP90B1, PIK3R5, GNB1, GNG5, GNG10, ITGB4, CHAD, COL1A1, TNC, LAMA4, LAMB3, TNXB, TLR2, IL2RB, IFNA21, CREBL1, ATF4, BCL2, PRKCA, SGK, PIK3AP1, CCND3More
Triazolamhsa04210Apoptosis3.32E-0512P04637, O76075, P01375, Q9NR28, O75460, P24522, Q16548, O43521, P43234, P18848, P63261, P04049TP53, DFFB, TNF, DIABLO, ERN1, GADD45A, BCL2A1, BCL2L11, CTSO, ATF4, ACTG1, RAF1More
Triazolamhsa04211Longevity regulating pathway1.32E-035P31751, Q08828, P51828, Q99941, P18848AKT2, ADCY1, ADCY7, CREBL1, ATF4More
Triazolamhsa04213Longevity regulating pathway - multiple species3.76E-046P31751, Q9Y4H2, Q08828, P51828, P0DMV8, Q13547AKT2, IRS2, ADCY1, ADCY7, HSPA1A, HDAC1More
Triazolamhsa04216Ferroptosis1.45E-022P04637, P49281TP53, SLC11A2More
Triazolamhsa04217Necroptosis6.40E-0922P01375, P01568, P23458, P48023, Q13489, Q9NQC7, Q13546, P42224, Q14765, P07900, P15104, P05141, P01584, P0C0S5, Q9BTM1, Q6FI13, Q99878, P10415, Q9H444, O43633, O75351, Q08752TNF, IFNA21, JAK1, FASLG, BIRC3, CYLD, RIPK1, STAT1, STAT4, HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, H2AFJ, H2AC18; H2AC19, H2AC14, BCL2, CHMP4B, CHMP2A, VPS4B, PPIDMore
Triazolamhsa04218Cellular senescence2.49E-021P04049RAF1More
Triazolamhsa04260Cardiac muscle contraction4.60E-033P67936, P13073, P12074TPM4, COX4I1, COX6A1More
Triazolamhsa04261Adrenergic signaling in cardiomyocytes5.21E-0712P09493, Q08828, P51828, P31751, Q99941, P18848, Q13362, Q14738, P0DP23, Q13557, P17252, P10415TPM1, ADCY1, ADCY7, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, CALM1, CAMK2D, PRKCA, BCL2More
Triazolamhsa04270Vascular smooth muscle contraction2.27E-037P0DP23, P04049, Q08828, P51828, P35579, P35749, P35318CALM1, RAF1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Triazolamhsa04310Wnt signaling pathway2.00E-044P61586, P17612, P19784, P67870RHOA, PRKACA, CSNK2A2, CSNK2BMore
Triazolamhsa04340Hedgehog signaling pathway2.36E-033P49841, P17612, P22694GSK3B, PRKACA, PRKACBMore
Triazolamhsa04360Axon guidance9.59E-048P16333, P20827, O95631, P17252, P42338, P07332, P04049, P19174NCK1, EFNA1, NTN1, PRKCA, PIK3CB, FES, RAF1, PLCG1More
Triazolamhsa04370VEGF signaling pathway3.32E-064P16298, Q05397, Q02750, P04049PPP3CB, PTK2, MAP2K1, RAF1More
Triazolamhsa04371Apelin signaling pathway2.31E-0614P62873, P63218, P50151, Q8WYR1, P31751, P04049, Q08828, P51828, Q13370, Q14814, Q14344, Q13485, P84022, P0DP23GNB1, GNG5, GNG10, PIK3R5, AKT2, RAF1, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, SMAD4, SMAD3, CALM1More
Triazolamhsa04380Osteoclast differentiation5.27E-0410Q9NQC7, Q9UQC2, Q16539, P23458, P31751, P01584, P14778, O75015, P01375, Q8N149CYLD, GAB2, MAPK14, JAK1, AKT2, IL1B, IL1R1, FCGR3B, TNF, LILRA2More
Triazolamhsa04390Hippo signaling pathway2.41E-034P63261, O15105, P04628, O43623ACTG1, SMAD7, WNT1, SNAI2More
Triazolamhsa04510Focal adhesion8.84E-034O14986, P61586, Q16363, P04049PIP5K1B, RHOA, LAMA4, RAF1More
Triazolamhsa04512ECM-receptor interaction7.53E-032P02452, P24821COL1A1, TNCMore
Triazolamhsa04520Adherens junction1.38E-043P19784, P67870, P61586CSNK2A2, CSNK2B, RHOAMore
Triazolamhsa04530Tight junction3.60E-035P63261, P16989, P56750, Q92974, Q14247ACTG1, CSDA, CLDN17, ARHGEF2, CTTNMore
Triazolamhsa04540Gap junction8.82E-057P17252, Q13509, P68371, Q71U36, P04049, Q9NRA1, Q14643PRKCA, TUBB3, TUBB2C, TUBA1A, RAF1, PDGFC, ITPR1More
Triazolamhsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P04049RAF1More
Triazolamhsa04611Platelet activation2.12E-022Q9Y490, P17612TLN1, PRKACAMore
Triazolamhsa04612Antigen processing and presentation2.68E-059P13765, P48382, P01730, P26715, P26717, Q07444, Q13241, O43908, P01732HLA-DOB, RFX5, CD4, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8AMore
Triazolamhsa04613Neutrophil extracellular trap formation5.32E-0717P19174, P17252, P04049, P11215, O60603, P08246, Q13547, Q6FI13, Q93077, P62807, P58876, Q16778, O60814, P68431, P14598, Q15080, P21462PLCG1, PRKCA, RAF1, ITGAM, TLR2, ELA2, HDAC1, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC5, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1More
Triazolamhsa04620Toll-like receptor signaling pathway1.84E-045Q13546, P01568, P01584, P31751, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, CCL4L2More
Triazolamhsa04621NOD-like receptor signaling pathway3.56E-037P01584, P07900, P43490, P01375, P59665, P59666, P12838IL1B, HSP90AA1, PBEF1, TNF, DEFA1; DEFA1B, DEFA3, DEFA4More
Triazolamhsa04622RIG-I-like receptor signaling pathway6.07E-032P01568, Q13546IFNA21, RIPK1More
Triazolamhsa04623Cytosolic DNA-sensing pathway7.16E-116P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Triazolamhsa04625C-type lectin receptor signaling pathway1.93E-049Q9ULY5, P04049, P01584, Q9NQC7, P20749, P01375, P31751, P0DP23, Q16539CLEC4E, RAF1, IL1B, CYLD, BCL3, TNF, AKT2, CALM1, MAPK14More
Triazolamhsa04630JAK-STAT signaling pathway8.73E-034P31751, P23458, Q13651, P04049AKT2, JAK1, IL10RA, RAF1More
Triazolamhsa04640Hematopoietic cell lineage1.60E-0410P13612, P14778, P27930, P25063, P07766, P09693, P01732, P01730, P09564, P13765ITGA4, IL1R1, IL1R2, CD24, CD3E, CD3G, CD8A, CD4, CD7, HLA-DOBMore
Triazolamhsa04650Natural killer cell mediated cytotoxicity1.43E-1016P16298, P50591, P01375, P78314, P06239, O60880, P20963, Q02750, P04049, Q13241, P26718, O14931, O75015, P26717, Q07444, P26715PPP3CB, TNFSF10, TNF, SH3BP2, LCK, SH2D1A, CD247, MAP2K1, RAF1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KLRC1More
Triazolamhsa04657IL-17 signaling pathway1.03E-0613P25963, P07900, P08238, O00463, Q07955, Q16539, P49841, P09341, P14780, P04141, P01375, P06702, P01584NFKBIA, HSP90AA1, HSP90AB1, TRAF5, SFRS1, MAPK14, GSK3B, CXCL1, MMP9, CSF2, TNF, S100A9, IL1BMore
Triazolamhsa04658Th1 and Th2 cell differentiation2.41E-1115P25963, Q04759, P07766, P20963, P09693, P19174, P01730, P06239, P42224, P23771, Q9UL17, P14784, Q9UM47, P13765, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, PLCG1, CD4, LCK, STAT1, GATA3, TBX21, IL2RB, NOTCH3, HLA-DOB, RUNX3More
Triazolamhsa04659Th17 cell differentiation1.17E-1017P25963, Q04759, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9UL17, P23771, P84022, Q13485, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, TBX21, GATA3, SMAD3, SMAD4, HSP90AB1, CD3E, CD3G, CD247More
Triazolamhsa04660T cell receptor signaling pathway1.84E-0813Q04759, O95267, Q08881, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P04049, Q16539, P49841PRKCQ, RASGRP1, ITK, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, RAF1, MAPK14, GSK3BMore
Triazolamhsa04662B cell receptor signaling pathway1.17E-056P42338, P60033, P07948, P21854, Q8N149, P04049PIK3CB, CD81, LYN, CD72, LILRA2, RAF1More
Triazolamhsa04664Fc epsilon RI signaling pathway9.17E-079P01375, P04141, Q16539, P42338, Q9UQC2, P07948, P19174, P04049, P09917TNF, CSF2, MAPK14, PIK3CB, GAB2, LYN, PLCG1, RAF1, ALOX5More
Triazolamhsa04666Fc gamma R-mediated phagocytosis2.32E-021P04049RAF1More
Triazolamhsa04668TNF signaling pathway1.56E-038P01375, O00463, Q16539, P18848, P01584, P20749, P14780, P20333TNF, TRAF5, MAPK14, ATF4, IL1B, BCL3, MMP9, TNFRSF1BMore
Triazolamhsa04672Intestinal immune network for IgA production3.76E-033P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Triazolamhsa04710Circadian rhythm4.40E-021O15516CLOCKMore
Triazolamhsa04713Circadian entrainment2.60E-059P0DP23, P17252, P62873, P63218, P50151, Q14643, Q08828, P51828, P63092CALM1, PRKCA, GNB1, GNG5, GNG10, ITPR1, ADCY1, ADCY7, GNASMore
Triazolamhsa04714Thermogenesis3.31E-024P51828, P62753, P12074, O15239ADCY7, RPS6, COX6A1, NDUFA1More
Triazolamhsa04720Long-term potentiation1.01E-059P17252, P16298, P0DP23, P51812, P18848, Q08828, Q02750, P04049, Q14643PRKCA, PPP3CB, CALM1, RPS6KA3, ATF4, ADCY1, MAP2K1, RAF1, ITPR1More
Triazolamhsa04722Neurotrophin signaling pathway7.10E-034P04049, P49841, O43524, P48023RAF1, GSK3B, FOXO3, FASLGMore
Triazolamhsa04723Retrograde endocannabinoid signaling2.51E-035Q14643, P17252, P48169, P62873, Q16718ITPR1, PRKCA, GABRA4, GNB1, NDUFA5More
Triazolamhsa04724Glutamatergic synapse2.48E-056O15399, P63092, P62873, P63218, P50151, P15104GRIN2D, GNAS, GNB1, GNG5, GNG10, GLULMore
Triazolamhsa04725Cholinergic synapse4.48E-0712Q08828, P51828, Q14643, P17252, P62873, P63218, P50151, P18848, Q13557, P42338, P31751, P10415ADCY1, ADCY7, ITPR1, PRKCA, GNB1, GNG5, GNG10, ATF4, CAMK2D, PIK3CB, AKT2, BCL2More
Triazolamhsa04726Serotonergic synapse4.42E-046P63092, P62873, P63218, P50151, P09917, P04049GNAS, GNB1, GNG5, GNG10, ALOX5, RAF1More
Triazolamhsa04727GABAergic synapse1.66E-044P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Triazolamhsa04728Dopaminergic synapse1.31E-0410Q14643, P17252, P62873, P31751, Q99941, P18848, Q13557, Q13362, Q14738, P0DP23ITPR1, PRKCA, GNB1, AKT2, CREBL1, ATF4, CAMK2D, PPP2R5C, PPP2R5D, CALM1More
Triazolamhsa04730Long-term depression1.95E-023Q14344, P04049, P07948GNA13, RAF1, LYNMore
Triazolamhsa04742Taste transduction3.91E-021P17612PRKACAMore
Triazolamhsa04744Phototransduction8.94E-072P62873, P0DP23GNB1, CALM1More
Triazolamhsa04750Inflammatory mediator regulation of TRP channels5.85E-055P01584, Q08828, P51828, Q13557, P0DP23IL1B, ADCY1, ADCY7, CAMK2D, CALM1More
Triazolamhsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Triazolamhsa04910Insulin signaling pathway2.51E-034P22694, P06737, P04049, P49841PRKACB, PYGL, RAF1, GSK3BMore
Triazolamhsa04911Insulin secretion5.68E-075Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Triazolamhsa04912GnRH signaling pathway3.27E-068P17252, Q08828, P51828, P18848, Q13557, Q14643, P0DP23, P04049PRKCA, ADCY1, ADCY7, ATF4, CAMK2D, ITPR1, CALM1, RAF1More
Triazolamhsa04914Progesterone-mediated oocyte maturation3.30E-045Q17RY0, Q9Y6D9, P51812, Q02750, P04049CPEB4, MAD1L1, RPS6KA3, MAP2K1, RAF1More
Triazolamhsa04915Estrogen signaling pathway1.10E-0511P04049, Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, P0DP23, Q15788RAF1, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, CALM1, NCOA1More
Triazolamhsa04916Melanogenesis5.16E-045Q13557, P0DP23, Q08828, P51828, P04049CAMK2D, CALM1, ADCY1, ADCY7, RAF1More
Triazolamhsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Triazolamhsa04918Thyroid hormone synthesis1.98E-045P51828, Q99941, P18848, P14625, P02768ADCY7, CREBL1, ATF4, HSP90B1, ALBMore
Triazolamhsa04919Thyroid hormone signaling pathway6.83E-045P49841, P04049, P22694, O60244, Q9NVC6GSK3B, RAF1, PRKACB, MED14, MED17More
Triazolamhsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Triazolamhsa04922Glucagon signaling pathway3.47E-024Q12778, Q13370, P0DP23, Q14643FOXO1, PDE3B, CALM1, ITPR1More
Triazolamhsa04923Regulation of lipolysis in adipocytes5.15E-033Q08828, P51828, P31751ADCY1, ADCY7, AKT2More
Triazolamhsa04924Renin secretion8.71E-033Q14643, Q13370, P0DP23ITPR1, PDE3B, CALM1More
Triazolamhsa04925Aldosterone synthesis and secretion3.41E-066Q99941, P18848, Q08828, P51828, P0DP23, Q13557CREBL1, ATF4, ADCY1, ADCY7, CALM1, CAMK2DMore
Triazolamhsa04926Relaxin signaling pathway1.22E-0511P31751, P42338, P63218, P50151, Q99941, P18848, P49767, Q08828, P51828, P04049, P49407AKT2, PIK3CB, GNG5, GNG10, CREBL1, ATF4, VEGFC, ADCY1, ADCY7, RAF1, ARRB1More
Triazolamhsa04927Cortisol synthesis and secretion1.29E-054Q99941, P18848, Q08828, P51828CREBL1, ATF4, ADCY1, ADCY7More
Triazolamhsa04928Parathyroid hormone synthesis, secretion and action3.95E-034P51828, P04049, Q99941, P18848ADCY7, RAF1, CREBL1, ATF4More
Triazolamhsa04929GnRH secretion3.50E-033P42338, P49407, P04049PIK3CB, ARRB1, RAF1More
Triazolamhsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Triazolamhsa04932Non-alcoholic fatty liver disease1.10E-1012P31751, P01375, P49841, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, O95298AKT2, TNF, GSK3B, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFC2More
Triazolamhsa04933AGE-RAGE signaling pathway in diabetic complications1.19E-039P84022, Q13485, P42224, P10415, P42338, Q12778, P49767, P17252, P19174SMAD3, SMAD4, STAT1, BCL2, PIK3CB, FOXO1, VEGFC, PRKCA, PLCG1More
Triazolamhsa04934Cushing syndrome8.15E-065Q99941, P18848, Q08828, P51828, Q13557CREBL1, ATF4, ADCY1, ADCY7, CAMK2DMore
Triazolamhsa04935Growth hormone synthesis, secretion and action3.68E-046Q08828, P51828, P04049, Q99941, P18848, P31751ADCY1, ADCY7, RAF1, CREBL1, ATF4, AKT2More
Triazolamhsa04940Type I diabetes mellitus6.87E-042P48023, P01375FASLG, TNFMore
Triazolamhsa04960Aldosterone-regulated sodium reabsorption4.40E-021O00141SGKMore
Triazolamhsa04962Vasopressin-regulated water reabsorption1.80E-022P62491, P46459RAB11A, NSFMore
Triazolamhsa04966Collecting duct acid secretion2.86E-022Q13488, Q9Y666TCIRG1, SLC12A7More
Triazolamhsa04970Salivary secretion1.89E-033Q08828, P51828, P0DP23ADCY1, ADCY7, CALM1More
Triazolamhsa04971Gastric acid secretion2.95E-055Q08828, P51828, P15311, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM1, CAMK2DMore
Triazolamhsa04972Pancreatic secretion3.65E-022P63092, P61586GNAS, RHOAMore
Triazolamhsa04974Protein digestion and absorption2.78E-021P02452COL1A1More
Triazolamhsa04976Bile secretion9.87E-055Q08828, P51828, P22694, P08183, Q14032ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Triazolamhsa05010Alzheimer disease3.99E-0722O15239, Q16718, O95298, O14521, P05496, P13073, P12074, Q14643, Q00535, O75460, P0DP23, P0DP24, P01584, O95197, P18848, Q13509, P68371, P67870, P31751, P05141, Q08752, P28070NDUFA1, NDUFA5, NDUFC2, SDHD, ATP5G1, COX4I1, COX6A1, ITPR1, CDK5, ERN1, CALM1, CALM2, IL1B, RTN3, ATF4, TUBB3, TUBB2C, CSNK2B, AKT2, SLC25A5, PPID, PSMB4More
Triazolamhsa05012Parkinson disease1.14E-0519O15239, Q16718, O14521, P13073, P12074, P05496, P05141, P60604, O75460, P18848, P28070, Q14643, P19174, P0DP23, P0DP24, Q13557, Q71U36, Q13509, P68371NDUFA1, NDUFA5, SDHD, COX4I1, COX6A1, ATP5G1, SLC25A5, UBE2G2, ERN1, ATF4, PSMB4, ITPR1, PLCG1, CALM1, CALM2, CAMK2D, TUBA1A, TUBB3, TUBB2CMore
Triazolamhsa05016Huntington disease1.70E-0612O15239, O95298, P13073, P12074, P05496, P24928, P30876, P62487, P05141, O75460, P28070, O00232NDUFA1, NDUFC2, COX4I1, COX6A1, ATP5G1, POLR2A, POLR2B, POLR2G, SLC25A5, ERN1, PSMB4, PSMD12More
Triazolamhsa05017Spinocerebellar ataxia3.94E-024O75460, P31751, P28070, P05141ERN1, AKT2, PSMB4, SLC25A5More
Triazolamhsa05020Prion disease1.59E-0315P01584, P46531, O15239, Q16718, O14521, P05496, P12074, Q14643, P18848, P05141, P28070, Q13509, P68371, P14598, Q15080IL1B, NOTCH1, NDUFA1, NDUFA5, SDHD, ATP5G1, COX6A1, ITPR1, ATF4, SLC25A5, PSMB4, TUBB3, TUBB2C, NCF1, NCF4More
Triazolamhsa05022Pathways of neurodegeneration - multiple diseases2.09E-0625Q14643, Q13509, P68371, P10415, O15239, Q16718, O95298, O14521, P13073, P12074, P05496, Q8TEV9, O75460, P18848, Q13561, P05141, P17252, P20333, Q00535, P01584, Q08752, P0DP23, P0DP24, Q13557, P28070ITPR1, TUBB3, TUBB2C, BCL2, NDUFA1, NDUFA5, NDUFC2, SDHD, COX4I1, COX6A1, ATP5G1, SMCR8, ERN1, ATF4, DCTN2, SLC25A5, PRKCA, TNFRSF1B, CDK5, IL1B, PPID, CALM1, CALM2, CAMK2D, PSMB4More
Triazolamhsa05030Cocaine addiction4.87E-022Q99941, P18848CREBL1, ATF4More
Triazolamhsa05031Amphetamine addiction6.41E-033Q13557, Q99941, P18848CAMK2D, CREBL1, ATF4More
Triazolamhsa05032Morphine addiction1.79E-058P62873, P63218, P50151, Q13370, P48169, P78334, P63092, P32298GNB1, GNG5, GNG10, PDE3B, GABRA4, GABRE, GNAS, GRK4More
Triazolamhsa05034Alcoholism1.44E-0610Q13547, P0DP23, P62873, P04049, Q93077, P62807, P58876, Q16778, O60814, P68431HDAC1, CALM1, GNB1, RAF1, HIST1H2AC, HIST1H2BC, H2BC5, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Triazolamhsa05110Vibrio cholerae infection1.74E-045Q13488, Q99437, P17252, P19174, P17612TCIRG1, ATP6V0B, PRKCA, PLCG1, PRKACAMore
Triazolamhsa05120Epithelial cell signaling in Helicobacter pylori infection6.88E-048Q16539, P25963, Q13488, P09341, P19174, P25024, P25025, P07948MAPK14, NFKBIA, TCIRG1, CXCL1, PLCG1, CXCR1, CXCR2, LYNMore
Triazolamhsa05130Pathogenic Escherichia coli infection3.19E-026Q71U36, P16333, Q13509, P68371, Q14344, P25963TUBA1A, NCK1, TUBB3, TUBB2C, GNA13, NFKBIAMore
Triazolamhsa05131Shigellosis2.27E-028P68431, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPIDMore
Triazolamhsa05132Salmonella infection8.15E-0414P25963, P08238, P04049, Q9UJU2, Q13489, P10415, O75369, O60603, Q9BQS8, Q13561, Q71U36, Q13509, P68371, P49754NFKBIA, HSP90AB1, RAF1, LEF1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41More
Triazolamhsa05134Legionellosis2.08E-046P01584, P25963, Q9NR31, P11215, P0DMV8, P11142IL1B, NFKBIA, SAR1A, ITGAM, HSPA1A, HSPA8More
Triazolamhsa05140Leishmaniasis1.20E-0611O75015, P14598, P11215, P42224, P13765, O60603, P25963, P29350, P49006, Q16539, Q15080FCGR3B, NCF1, ITGAM, STAT1, HLA-DOB, TLR2, NFKBIA, PTPN6, MARCKSL1, MAPK14, NCF4More
Triazolamhsa05142Chagas disease2.26E-023P01375, P30679, P48023TNF, GNA15, FASLGMore
Triazolamhsa05143African trypanosomiasis1.51E-032P01375, P48023TNF, FASLGMore
Triazolamhsa05144Malaria3.30E-024P60033, O60603, P35443, P26718CD81, TLR2, THBS4, KLRK1More
Triazolamhsa05145Toxoplasmosis1.11E-026P10415, Q13489, P42224, P13765, O60603, P29965BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LGMore
Triazolamhsa05146Amoebiasis1.17E-047P09341, P14778, P27930, O60603, P05089, P12814, P08311CXCL1, IL1R1, IL1R2, TLR2, ARG1, ACTN1, CTSGMore
Triazolamhsa05150Staphylococcus aureus infection9.80E-045Q14532, P59665, P59666, P12838, P49913KRT32, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Triazolamhsa05152Tuberculosis9.31E-049P04049, Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8RAF1, TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1More
Triazolamhsa05160Hepatitis C1.31E-047Q13546, P01568, P60033, P04049, P49841, P01375, P48023RIPK1, IFNA21, CD81, RAF1, GSK3B, TNF, FASLGMore
Triazolamhsa05161Hepatitis B5.33E-034P04049, Q99941, P18848, P27348RAF1, CREBL1, ATF4, YWHAQMore
Triazolamhsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Triazolamhsa05163Human cytomegalovirus infection9.89E-1229P31751, P04049, P01375, P25963, P62873, P63218, P50151, Q14643, P0DP23, Q14344, P61586, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, P61073, Q13651, P25025, Q16539, P18848, P63092, P04637, O00463, P30101, P61769, P01568AKT2, RAF1, TNF, NFKBIA, GNB1, GNG5, GNG10, ITPR1, CALM1, GNA13, RHOA, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, CXCR4, IL10RA, CXCR2, MAPK14, ATF4, GNAS, TP53, TRAF5, PDIA3, B2M, IFNA21More
Triazolamhsa05164Influenza A1.49E-026P31751, P01584, P23458, P05141, P04049, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, RAF1, NXF1More
Triazolamhsa05165Human papillomavirus infection9.67E-0411P16144, P02452, P24821, Q05086, P01568, P42224, Q13488, Q13362, Q12778, P04628, Q13315ITGB4, COL1A1, TNC, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, WNT1, ATMMore
Triazolamhsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Triazolamhsa05167Kaposi sarcoma-associated herpesvirus infection1.06E-0717P01568, P42224, P25963, P62873, P62879, P63218, P50151, P19174, P16298, Q14643, P04049, Q02750, P07948, P04141, P0DP23, P0CG47, Q9UJU2IFNA21, STAT1, NFKBIA, GNB1, GNB2, GNG5, GNG10, PLCG1, PPP3CB, ITPR1, RAF1, MAP2K1, LYN, CSF2, CALM1, UBB, LEF1More
Triazolamhsa05168Herpes simplex virus 1 infection7.90E-0415P25963, P01568, P42224, Q07955, Q01130, Q13243, P30101, Q9Y2A4, Q13398, P51522, P17038, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, PDIA3, ZNF443, ZNF211, ZNF83, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212More
Triazolamhsa05169Epstein-Barr virus infection5.94E-0412P13765, P01106, Q13547, O00463, P42338, P07948, Q13761, P24522, O75293, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, PIK3CB, LYN, RUNX3, GADD45A, GADD45B, CD3E, CD3G, CD247More
Triazolamhsa05170Human immunodeficiency virus 1 infection8.67E-0720P04049, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, Q05397, P17252, P30101, Q14643, P01568, P25963, O60603, Q13315, P19174, P10415, Q9Y6Q5, P20333RAF1, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, PTK2, PRKCA, PDIA3, ITPR1, IFNA21, NFKBIA, TLR2, ATM, PLCG1, BCL2, AP1M2, TNFRSF1BMore
Triazolamhsa05171Coronavirus disease - COVID-191.70E-0815P01584, P23396, P62753, P62249, P62906, Q9UHA3, P36578, P27635, Q07020, P62888, P46776, P61927, P61513, P62829, O14786IL1B, RPS3, RPS6, RPS16, RPL10A, RSL24D1, RPL4, RPL10, RPL18, RPL30, RPL27A, RPL37, RPL37A, RPL23, NRP1More
Triazolamhsa05200Pathways in cancer3.02E-0631Q13751, P42338, P08238, P42224, P25963, P19174, Q9UJU2, P17252, P43246, P84022, Q13485, P20585, Q13547, P14923, P30281, P10415, Q13489, P49767, Q12778, P43657, P25116, P62873, P63218, P50151, Q14344, Q7LDG7, Q9UM47, O75293, P0DP23, P01568, P14784LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, LEF1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, HDAC1, JUP, CCND3, BCL2, BIRC3, VEGFC, FOXO1, P2RY5, F2R, GNB1, GNG5, GNG10, GNA13, RASGRP2, NOTCH3, GADD45B, CALM1, IFNA21, IL2RBMore
Triazolamhsa05202Transcriptional misregulation in cancer1.24E-024P27930, P11215, Q13547, P12980IL1R2, ITGAM, HDAC1, LYL1More
Triazolamhsa05203Viral carcinogenesis2.91E-0512Q99941, P18848, P23458, P27348, Q7KZF4, Q13547, Q15283, P61978, P58876, P62807, Q16778, O60814CREBL1, ATF4, JAK1, YWHAQ, SND1, HDAC1, RASA2, HNRPK, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12More
Triazolamhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Triazolamhsa05205Proteoglycans in cancer3.48E-021P04049RAF1More
Triazolamhsa05206MicroRNAs in cancer1.30E-027P30304, P09493, Q9UM47, P20827, P17252, P19174, P04049CDC25A, TPM1, NOTCH3, EFNA1, PRKCA, PLCG1, RAF1More
Triazolamhsa05210Colorectal cancer2.55E-033Q9UKG1, P04049, P37173APPL1, RAF1, TGFBR2More
Triazolamhsa05211Renal cell carcinoma1.28E-033Q06124, Q99814, P04049PTPN11, EPAS1, RAF1More
Triazolamhsa05212Pancreatic cancer8.71E-0611P42338, P31751, P04049, Q15311, P23458, P42224, P84022, Q13485, P04637, P24522, O75293PIK3CB, AKT2, RAF1, RALBP1, JAK1, STAT1, SMAD3, SMAD4, TP53, GADD45A, GADD45BMore
Triazolamhsa05213Endometrial cancer3.26E-045O15169, Q02750, P04049, P04637, P24522AXIN1, MAP2K1, RAF1, TP53, GADD45AMore
Triazolamhsa05214Glioma1.52E-057P0DP23, P17252, P04049, P04637, P19174, P24522, O75293CALM1, PRKCA, RAF1, TP53, PLCG1, GADD45A, GADD45BMore
Triazolamhsa05215Prostate cancer3.72E-033P18848, P14625, P04049ATF4, HSP90B1, RAF1More
Triazolamhsa05216Thyroid cancer1.45E-022P04637, P24522TP53, GADD45AMore
Triazolamhsa05217Basal cell carcinoma2.60E-022P04637, P24522TP53, GADD45AMore
Triazolamhsa05218Melanoma7.17E-043P04637, P04049, P24522TP53, RAF1, GADD45AMore
Triazolamhsa05219Bladder cancer5.65E-033P14780, P04637, P04049MMP9, TP53, RAF1More
Triazolamhsa05220Chronic myeloid leukemia1.52E-049Q06124, P04637, Q13547, Q13485, P84022, P42338, P04049, P24522, O75293PTPN11, TP53, HDAC1, SMAD4, SMAD3, PIK3CB, RAF1, GADD45A, GADD45BMore
Triazolamhsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Triazolamhsa05223Non-small cell lung cancer2.07E-033P04049, P04637, P24522RAF1, TP53, GADD45AMore
Triazolamhsa05224Breast cancer1.24E-025P04049, P49841, Q92837, P04637, P24522RAF1, GSK3B, FRAT1, TP53, GADD45AMore
Triazolamhsa05225Hepatocellular carcinoma3.15E-034P04049, P04637, P24522, P63261RAF1, TP53, GADD45A, ACTG1More
Triazolamhsa05226Gastric cancer3.26E-033P04049, Q02750, O15169RAF1, MAP2K1, AXIN1More
Triazolamhsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Triazolamhsa05231Choline metabolism in cancer2.00E-069P04049, P31751, Q9Y259, P19174, P23743, P49619, Q16760, O14986, P17252RAF1, AKT2, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PRKCAMore
Triazolamhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer4.68E-0610O95267, P07766, P20963, P09693, P06239, P04049, O60603, Q04759, Q16539, P01730RASGRP1, CD3E, CD247, CD3G, LCK, RAF1, TLR2, PRKCQ, MAPK14, CD4More
Triazolamhsa05320Autoimmune thyroid disease1.27E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Triazolamhsa05322Systemic lupus erythematosus1.61E-0814P08246, P08311, P09871, P10747, P13765, P29965, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, P12814ELA2, CTSG, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1More
Triazolamhsa05323Rheumatoid arthritis1.29E-024P13765, Q13488, P10747, O60603HLA-DOB, TCIRG1, CD28, TLR2More
Triazolamhsa05330Allograft rejection6.97E-055P13765, P29965, P48023, P10747, P01375HLA-DOB, CD40LG, FASLG, CD28, TNFMore
Triazolamhsa05332Graft-versus-host disease3.62E-055P13765, P48023, P01375, P26715, Q13241HLA-DOB, FASLG, TNF, KLRC1, KLRD1More
Triazolamhsa05340Primary immunodeficiency2.19E-024P01730, P01732, P07766, P06239CD4, CD8A, CD3E, LCKMore
Triazolamhsa05415Diabetic cardiomyopathy5.94E-037P17252, P30405, P14598, Q15080, Q16718, O14521, P37173PRKCA, PPIF, NCF1, NCF4, NDUFA5, SDHD, TGFBR2More
Triazolamhsa05416Viral myocarditis2.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More
Triazolamhsa05418Fluid shear stress and atherosclerosis1.26E-048Q16539, Q14145, P10599, P14780, P01375, P04637, P14778, P27930MAPK14, KEAP1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2More

Community members of Triazolam (SDC: 9.32)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P48169GABRA4GammaNoneaminobutyric acid receptor subunit alphaNone4Reported00.32530.5650.15791.4506
P28472GABRB3GammaNoneaminobutyric acid receptor subunit betaNone3Reported00.15590.43870.16951.1248
P78334GABREGammaNoneaminobutyric acid receptor subunit epsilonReported00.13940.40970.15791.0469
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P62942FKBP1APeptidylNoneprolyl cisNonetrans isomerase FKBP1APredicted10.4320.269500.7551
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
O14684PTGESProstaglandin E synthasePredicted10.45310.63580.15651.6547
P61073CXCR4CNoneXNoneC chemokine receptor type 4Predicted10.28230.40180.6481.5927
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
Q9HAZ1CLK4Dual specificity protein kinase CLK4Predicted00.28830.31110.15870.9251
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
P49760CLK2Dual specificity protein kinase CLK2Predicted00.03030.295100.6053
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P11388TOP2ADNA topoisomerase 2NonealphaPredicted00.19920.46590.19271.2242
P17252PRKCAProtein kinase C alpha typePredicted00.14090.694812.4601
P17612PRKACAcAMPNonedependent protein kinase catalytic subunit alphaPredicted00.69370.525712.3982
Q9GZT9EGLN1Egl nine homolog 1Predicted00.58040.60610.25561.7581
P11766ADH5Alcohol dehydrogenase classNone3Predicted00.2650.13970.21460.6265
P04818TYMSThymidylate synthasePredicted10.45530.27060.18930.9582
Q99814EPAS1Endothelial PAS domainNonecontaining protein 1Predicted00.23220.0620.24910.4892
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
P00325ADH1BAllNonetransNoneretinol dehydrogenase [NAD(+)] ADH1BPredicted00.75050.04520.1530.6186
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
P07900HSP90AA1Heat shock protein HSP 90NonealphaPredicted10.47270.60640.7412.1901
P14625HSP90B1EndoplasminPredicted00.23360.14970.53840.9546
P08238HSP90AB1Heat shock protein HSP 90NonebetaPredicted00.06110.52080.7411.8131
P37173TGFBR2TGFNonebeta receptor typeNone2Predicted00.28670.3790.87421.7755
O00141SGKSerine/threonineNoneprotein kinase Sgk1Predicted00.24130.30370.30591.034
P63279UBE2ISUMONoneconjugating enzyme UBC9Predicted00.23320.05120.49830.7173
P42224STAT1Signal transducer and activator of transcription 1Nonealpha/betaPredicted10.22450.042511.1973
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)