PharmaCoNets of Triamcinolone (SPCN: 43.48 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Triamcinolonehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Triamcinolonehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Triamcinolonehsa00190Oxidative phosphorylation8.71E-033Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Triamcinolonehsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Triamcinolonehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Triamcinolonehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Triamcinolonehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Triamcinolonehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Triamcinolonehsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Triamcinolonehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Triamcinolonehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Triamcinolonehsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Triamcinolonehsa04064NF-kappa B signaling pathway1.34E-038P10415, Q13489, Q13546, P29965, Q9UDY8, Q8WV28, Q13315, Q9UNE0BCL2, BIRC3, RIPK1, CD40LG, MALT1, BLNK, ATM, EDARMore
Triamcinolonehsa04070Phosphatidylinositol signaling system3.47E-024P0DP23, Q14643, P23743, P17252CALM1, ITPR1, DGKA, PRKCAMore
Triamcinolonehsa04071Sphingolipid signaling pathway2.87E-037P17252, Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2PRKCA, EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2More
Triamcinolonehsa04145Phagosome1.59E-037Q15080, P14598, Q13509, P68371, Q13488, O60603, P13765NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, TLR2, HLA-DOBMore
Triamcinolonehsa04151PI3K-Akt signaling pathway4.50E-029P25116, P49767, Q13362, P62873, P16144, O60603, P01568, P10415, P17252F2R, VEGFC, PPP2R5C, GNB1, ITGB4, TLR2, IFNA21, BCL2, PRKCAMore
Triamcinolonehsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Triamcinolonehsa04211Longevity regulating pathway1.18E-023Q12778, Q9UEF7, Q96KQ7FOXO1, KL, EHMT2More
Triamcinolonehsa04217Necroptosis9.70E-048P01568, Q13489, Q13546, P42224, Q6FI13, P10415, O43633, Q08752IFNA21, BIRC3, RIPK1, STAT1, H2AC18; H2AC19, BCL2, CHMP2A, PPIDMore
Triamcinolonehsa04261Adrenergic signaling in cardiomyocytes2.84E-025P09493, Q13362, P0DP23, P17252, P10415TPM1, PPP2R5C, CALM1, PRKCA, BCL2More
Triamcinolonehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Triamcinolonehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Triamcinolonehsa04540Gap junction1.29E-024P17252, Q13509, P68371, Q14643PRKCA, TUBB3, TUBB2C, ITPR1More
Triamcinolonehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Triamcinolonehsa04612Antigen processing and presentation4.78E-026P48382, P26715, P26717, Q13241, O43908, P01375RFX5, KLRC1, KLRC2, KLRD1, KLRC4, TNFMore
Triamcinolonehsa04613Neutrophil extracellular trap formation2.54E-0311P17252, O60603, P08246, Q6FI13, Q93077, P62807, O60814, P68431, P14598, Q15080, P21462PRKCA, TLR2, ELA2, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1More
Triamcinolonehsa04620Toll-like receptor signaling pathway4.16E-022Q13546, P01568RIPK1, IFNA21More
Triamcinolonehsa04621NOD-like receptor signaling pathway4.48E-0312P01568, Q13489, Q9H1Y0, P43490, O00463, Q13546, Q05823, P01375, P49913, P59665, P59666, P12838IFNA21, BIRC3, ATG5, PBEF1, TRAF5, RIPK1, RNASEL, TNF, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Triamcinolonehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Triamcinolonehsa04623Cytosolic DNA-sensing pathway2.20E-032P01568, Q13546IFNA21, RIPK1More
Triamcinolonehsa04650Natural killer cell mediated cytotoxicity1.25E-028P01375, O60880, P20963, Q13241, P26718, O75015, P26717, P26715TNF, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Triamcinolonehsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Triamcinolonehsa04672Intestinal immune network for IgA production3.76E-033P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Triamcinolonehsa04713Circadian entrainment2.60E-024P0DP23, P17252, P62873, Q14643CALM1, PRKCA, GNB1, ITPR1More
Triamcinolonehsa04720Long-term potentiation3.89E-023P17252, P0DP23, Q14643PRKCA, CALM1, ITPR1More
Triamcinolonehsa04723Retrograde endocannabinoid signaling1.88E-024Q14643, P17252, P62873, Q16718ITPR1, PRKCA, GNB1, NDUFA5More
Triamcinolonehsa04725Cholinergic synapse1.88E-024Q14643, P17252, P62873, P10415ITPR1, PRKCA, GNB1, BCL2More
Triamcinolonehsa04728Dopaminergic synapse3.55E-025Q14643, P17252, P62873, Q13362, P0DP23ITPR1, PRKCA, GNB1, PPP2R5C, CALM1More
Triamcinolonehsa04744Phototransduction1.02E-022P62873, P0DP23GNB1, CALM1More
Triamcinolonehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Triamcinolonehsa04912GnRH signaling pathway3.89E-023P17252, Q14643, P0DP23PRKCA, ITPR1, CALM1More
Triamcinolonehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Triamcinolonehsa04922Glucagon signaling pathway3.47E-024Q12778, Q13370, P0DP23, Q14643FOXO1, PDE3B, CALM1, ITPR1More
Triamcinolonehsa04924Renin secretion8.71E-033Q14643, Q13370, P0DP23ITPR1, PDE3B, CALM1More
Triamcinolonehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Triamcinolonehsa04933AGE-RAGE signaling pathway in diabetic complications1.27E-025P42224, P10415, Q12778, P49767, P17252STAT1, BCL2, FOXO1, VEGFC, PRKCAMore
Triamcinolonehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Triamcinolonehsa04966Collecting duct acid secretion2.07E-033Q13488, P00918, Q9Y666TCIRG1, CA2, SLC12A7More
Triamcinolonehsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Triamcinolonehsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Triamcinolonehsa05010Alzheimer disease3.55E-027Q16718, O14521, Q14643, P0DP23, Q13509, P68371, Q08752NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2C, PPIDMore
Triamcinolonehsa05012Parkinson disease2.25E-026Q16718, O14521, Q14643, P0DP23, Q13509, P68371NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2CMore
Triamcinolonehsa05020Prion disease1.15E-027Q16718, O14521, Q14643, Q13509, P68371, P14598, Q15080NDUFA5, SDHD, ITPR1, TUBB3, TUBB2C, NCF1, NCF4More
Triamcinolonehsa05022Pathways of neurodegeneration - multiple diseases4.48E-0310Q14643, Q13509, P68371, P10415, Q16718, O14521, Q13561, P17252, Q08752, P0DP23ITPR1, TUBB3, TUBB2C, BCL2, NDUFA5, SDHD, DCTN2, PRKCA, PPID, CALM1More
Triamcinolonehsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Triamcinolonehsa05131Shigellosis2.27E-028P68431, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPIDMore
Triamcinolonehsa05132Salmonella infection5.51E-0410Q9UJU2, Q13546, Q13489, P10415, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371LEF1, RIPK1, BIRC3, BCL2, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2CMore
Triamcinolonehsa05133Pertussis4.20E-021P0C0L4C4AMore
Triamcinolonehsa05140Leishmaniasis2.17E-036P14598, P42224, P13765, O60603, P29350, Q15080NCF1, STAT1, HLA-DOB, TLR2, PTPN6, NCF4More
Triamcinolonehsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Triamcinolonehsa05144Malaria3.76E-036P60033, P69905, P68871, P01375, P35443, P26718CD81, HBA2, HBB, TNF, THBS4, KLRK1More
Triamcinolonehsa05145Toxoplasmosis1.11E-026P10415, Q13489, P42224, P13765, O60603, P29965BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LGMore
Triamcinolonehsa05150Staphylococcus aureus infection1.02E-037P21730, P21462, O75015, P59665, P59666, P12838, P49913C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Triamcinolonehsa05152Tuberculosis7.93E-048Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1More
Triamcinolonehsa05165Human papillomavirus infection3.10E-028P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATMMore
Triamcinolonehsa05167Kaposi sarcoma-associated herpesvirus infection4.73E-026P01568, P42224, P62873, Q14643, P0DP23, Q9UJU2IFNA21, STAT1, GNB1, ITPR1, CALM1, LEF1More
Triamcinolonehsa05170Human immunodeficiency virus 1 infection4.67E-039P62873, P0DP23, P17252, Q14643, P01568, O60603, Q13315, P10415, Q9Y6Q5GNB1, CALM1, PRKCA, ITPR1, IFNA21, TLR2, ATM, BCL2, AP1M2More
Triamcinolonehsa05200Pathways in cancer4.99E-0212P42224, Q9UJU2, P17252, P14923, P10415, Q13489, P49767, Q12778, P25116, P62873, P0DP23, P01568STAT1, LEF1, PRKCA, JUP, BCL2, BIRC3, VEGFC, FOXO1, F2R, GNB1, CALM1, IFNA21More
Triamcinolonehsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Triamcinolonehsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Triamcinolonehsa05320Autoimmune thyroid disease1.27E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Triamcinolonehsa05322Systemic lupus erythematosus4.80E-0610P08246, P09871, P10747, P13765, P29965, Q6FI13, Q93077, P62807, O60814, P68431ELA2, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Triamcinolonehsa05323Rheumatoid arthritis1.29E-024P13765, Q13488, P10747, O60603HLA-DOB, TCIRG1, CD28, TLR2More
Triamcinolonehsa05330Allograft rejection1.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More
Triamcinolonehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Triamcinolonehsa05415Diabetic cardiomyopathy3.55E-025P17252, P14598, Q15080, Q16718, O14521PRKCA, NCF1, NCF4, NDUFA5, SDHDMore
Triamcinolonehsa05416Viral myocarditis2.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More

Community members of Triamcinolone (SDC: 4.62)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08235NR3C2Mineralocorticoid receptorPredicted10.185510.01372.1064
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P01375TNFTumor necrosis factorPredicted10.18650.55112.1953
P17252PRKCAProtein kinase C alpha typePredicted00.14090.694812.4601
P01375TNFTumor necrosis factorPredicted10.18650.55112.1953
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)