| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Treprostinil | hsa04145 | Phagosome | 3.99E-02 | 4 | P05164, P78380, P35443, P13765 | MPO, OLR1, THBS4, HLA-DOB | More | | | Treprostinil | hsa04612 | Antigen processing and presentation | 1.31E-03 | 6 | P13765, P26715, P26717, Q07444, Q13241, P01732 | HLA-DOB, KLRC1, KLRC2, KLRC3, KLRD1, CD8A | More | | | Treprostinil | hsa04640 | Hematopoietic cell lineage | 4.90E-03 | 6 | P25063, P07766, P01732, P09564, P13765, P09603 | CD24, CD3E, CD8A, CD7, HLA-DOB, CSF1 | More | | | Treprostinil | hsa04650 | Natural killer cell mediated cytotoxicity | 9.26E-06 | 9 | P06239, O60880, P20963, Q13241, P26718, O14931, P26717, Q07444, P26715 | LCK, SH2D1A, CD247, KLRD1, KLRK1, NCR3, KLRC2, KLRC3, KLRC1 | More | | | Treprostinil | hsa04658 | Th1 and Th2 cell differentiation | 5.90E-06 | 8 | Q04759, P07766, P20963, P06239, Q14765, Q9UL17, P13765, Q13761 | PRKCQ, CD3E, CD247, LCK, STAT4, TBX21, HLA-DOB, RUNX3 | More | | | Treprostinil | hsa04659 | Th17 cell differentiation | 3.38E-04 | 7 | Q04759, P06239, P13765, Q9HBE5, Q9UL17, P07766, P20963 | PRKCQ, LCK, HLA-DOB, IL21R, TBX21, CD3E, CD247 | More | | | Treprostinil | hsa04660 | T cell receptor signaling pathway | 8.49E-04 | 7 | Q04759, Q08881, P07766, P20963, P01732, Q13191, P06239 | PRKCQ, ITK, CD3E, CD247, CD8A, CBLB, LCK | More | | | Treprostinil | hsa04750 | Inflammatory mediator regulation of TRP channels | 4.74E-02 | 3 | P22694, P24723, Q04759 | PRKACB, PRKCH, PRKCQ | More | | | Treprostinil | hsa04913 | Ovarian steroidogenesis | 2.72E-02 | 2 | P42330, P22694 | AKR1C3, PRKACB | More | | | Treprostinil | hsa05146 | Amoebiasis | 6.67E-04 | 6 | P09341, P19875, P05089, P22694, P12814, P08311 | CXCL1, CXCL2, ARG1, PRKACB, ACTN1, CTSG | More | | | Treprostinil | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 2.73E-02 | 4 | P07766, P20963, P06239, Q04759 | CD3E, CD247, LCK, PRKCQ | More | | | Treprostinil | hsa05310 | Asthma | 2.72E-02 | 2 | P13765, P12724 | HLA-DOB, RNASE3 | More | | | Treprostinil | hsa05321 | Inflammatory bowel disease | 2.22E-03 | 4 | P13765, Q14765, Q9UL17, Q9HBE5 | HLA-DOB, STAT4, TBX21, IL21R | More | | | Treprostinil | hsa05323 | Rheumatoid arthritis | 3.51E-03 | 4 | P09603, P13765, P09341, P19875 | CSF1, HLA-DOB, CXCL1, CXCL2 | More | | | Treprostinil | hsa05332 | Graft-versus-host disease | 9.74E-03 | 3 | P13765, P26715, Q13241 | HLA-DOB, KLRC1, KLRD1 | More | | | Treprostinil | hsa05340 | Primary immunodeficiency | 2.86E-02 | 3 | P01732, P07766, P06239 | CD8A, CD3E, LCK | More | |
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