| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Testosterone-propionate | hsa00030 | Pentose phosphate pathway | 9.18E-05 | 4 | P60891, P52209, P11413, P37837 | PRPS1, PGD, G6PD, TALDO1 | More | | | Testosterone-propionate | hsa00040 | Pentose and glucuronate interconversions | 3.53E-02 | 1 | O60701 | UGDH | More | | | Testosterone-propionate | hsa00052 | Galactose metabolism | 1.06E-03 | 2 | P06280, O43451 | GLA, MGAM | More | | | Testosterone-propionate | hsa00190 | Oxidative phosphorylation | 8.71E-03 | 3 | Q16718, Q13488, O14521 | NDUFA5, TCIRG1, SDHD | More | | | Testosterone-propionate | hsa00220 | Arginine biosynthesis | 5.12E-03 | 2 | P05089, P49448 | ARG1, GLUD2 | More | | | Testosterone-propionate | hsa00250 | Alanine, aspartate and glutamate metabolism | 4.88E-02 | 1 | P49448 | GLUD2 | More | | | Testosterone-propionate | hsa00310 | Lysine degradation | 3.15E-02 | 2 | Q96KQ7, P51648 | EHMT2, ALDH3A2 | More | | | Testosterone-propionate | hsa00471 | D-Glutamine and D-glutamate metabolism | 1.65E-02 | 1 | P49448 | GLUD2 | More | | | Testosterone-propionate | hsa00480 | Glutathione metabolism | 1.35E-02 | 1 | P11413 | G6PD | More | | | Testosterone-propionate | hsa00500 | Starch and sucrose metabolism | 1.36E-06 | 4 | O43451, P46976, P35573, P06737 | MGAM, GYG1, AGL, PYGL | More | | | Testosterone-propionate | hsa00512 | Mucin type O-glycan biosynthesis | 3.78E-02 | 2 | O95395, Q8N4A0 | GCNT3, GALNT4 | More | | | Testosterone-propionate | hsa00533 | Glycosaminoglycan biosynthesis - keratan sulfate | 3.43E-02 | 1 | Q9NY97 | B3GNT2 | More | | | Testosterone-propionate | hsa00590 | Arachidonic acid metabolism | 2.48E-03 | 3 | P11712, P09917, P09960 | CYP2C9, ALOX5, LTA4H | More | | | Testosterone-propionate | hsa00591 | Linoleic acid metabolism | 4.07E-02 | 1 | P11712 | CYP2C9 | More | | | Testosterone-propionate | hsa00600 | Sphingolipid metabolism | 3.76E-02 | 1 | P15289 | ARSA | More | | | Testosterone-propionate | hsa00630 | Glyoxylate and dicarboxylate metabolism | 5.51E-05 | 2 | P40925, P15104 | MDH1, GLUL | More | | | Testosterone-propionate | hsa00730 | Thiamine metabolism | 2.39E-05 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Testosterone-propionate | hsa00770 | Pantothenate and CoA biosynthesis | 1.15E-02 | 2 | O95498, Q9NRN7 | VNN2, AASDHPPT | More | | | Testosterone-propionate | hsa00830 | Retinol metabolism | 3.93E-02 | 3 | P00352, Q9BPW9, O75911 | ALDH1A1, DHRS9, DHRS3 | More | | | Testosterone-propionate | hsa00910 | Nitrogen metabolism | 4.88E-02 | 1 | P49448 | GLUD2 | More | | | Testosterone-propionate | hsa00920 | Sulfur metabolism | 3.18E-02 | 1 | Q16762 | TST | More | | | Testosterone-propionate | hsa00970 | Aminoacyl-tRNA biosynthesis | 3.78E-02 | 2 | O95363, Q15046 | FARS2, KARS | More | | | Testosterone-propionate | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 9.14E-03 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Testosterone-propionate | hsa00982 | Drug metabolism - cytochrome P450 | 9.14E-03 | 2 | P11712, P78417 | CYP2C9, GSTO1 | More | | | Testosterone-propionate | hsa00983 | Drug metabolism - other enzymes | 2.44E-02 | 2 | P32320, P05164 | CDA, MPO | More | | | Testosterone-propionate | hsa01100 | Metabolic pathways | 4.43E-02 | 23 | Q9NR34, P05089, P32320, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737 | MAN1C1, ARG1, CDA, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL | More | | | Testosterone-propionate | hsa01200 | Carbon metabolism | 2.00E-03 | 3 | P11413, P52209, P37837 | G6PD, PGD, TALDO1 | More | | | Testosterone-propionate | hsa01210 | 2-Oxocarboxylic acid metabolism | 3.43E-02 | 1 | P50213 | IDH3A | More | | | Testosterone-propionate | hsa01240 | Biosynthesis of cofactors | 1.34E-03 | 4 | P13716, P36551, O60701, P14618 | ALAD, CPOX, UGDH, PKM2 | More | | | Testosterone-propionate | hsa01521 | EGFR tyrosine kinase inhibitor resistance | 1.82E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa01522 | Endocrine resistance | 2.16E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa01523 | Antifolate resistance | 3.80E-02 | 2 | Q92820, P04818 | GGH, TYMS | More | | | Testosterone-propionate | hsa02010 | ABC transporters | 4.48E-02 | 1 | Q8IZY2 | ABCA7 | More | | | Testosterone-propionate | hsa03013 | RNA transport | 2.99E-02 | 4 | P38919, P37198, P35658, P55884 | EIF4A3, NUP62, NUP214, EIF3B | More | | | Testosterone-propionate | hsa03020 | RNA polymerase | 3.00E-02 | 3 | P30876, P24928, P62487 | POLR2B, POLR2A, POLR2G | More | | | Testosterone-propionate | hsa03040 | Spliceosome | 1.64E-09 | 13 | O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643 | DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O43143 | DHX15 | ATP-dependent RNA helicase DHX15 | -0.76 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | O60508 | CDC40 | Pre-mRNA-processing factor 17 | 0.76 | | P07948 | LYN | Tyrosine-protein kinase Lyn | O60508 | CDC40 | Pre-mRNA-processing factor 17 | -0.814 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O60508 | CDC40 | Pre-mRNA-processing factor 17 | -0.812 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | P08579 | SNRPB2 | U2 small nuclear ribonucleoprotein B'' | 0.787 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P08579 | SNRPB2 | U2 small nuclear ribonucleoprotein B'' | -0.739 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P08579 | SNRPB2 | U2 small nuclear ribonucleoprotein B'' | -0.822 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P26368 | U2AF2 | Splicing factor U2AF 65 kDa subunit | -0.775 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P26368 | U2AF2 | Splicing factor U2AF 65 kDa subunit | -0.751 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q13595 | TRA2A | Transformer-2 protein homolog alpha | -0.742 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13595 | TRA2A | Transformer-2 protein homolog alpha | -0.74 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | Q07955 | SFRS1 | Serine/arginine-rich splicing factor 1 | 0.712 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q07955 | SFRS1 | Serine/arginine-rich splicing factor 1 | -0.749 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | Q01130 | SFRS2 | Serine/arginine-rich splicing factor 2 | 0.822 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q01130 | SFRS2 | Serine/arginine-rich splicing factor 2 | -0.716 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q01130 | SFRS2 | Serine/arginine-rich splicing factor 2 | -0.798 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P84103 | SFRS3 | Serine/arginine-rich splicing factor 3 | -0.79 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P84103 | SFRS3 | Serine/arginine-rich splicing factor 3 | -0.773 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q13243 | SFRS5 | Serine/arginine-rich splicing factor 5 | -0.781 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13243 | SFRS5 | Serine/arginine-rich splicing factor 5 | -0.822 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P11142 | HSPA8 | Heat shock cognate 71 kDa protein | -0.732 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P11142 | HSPA8 | Heat shock cognate 71 kDa protein | -0.802 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | Q9Y2W2 | WBP11 | WW domain-binding protein 11 | 0.711 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q9Y2W2 | WBP11 | WW domain-binding protein 11 | -0.734 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q9Y2W2 | WBP11 | WW domain-binding protein 11 | -0.743 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O43447 | PPIH | Peptidyl-prolyl cis-trans isomerase H | -0.766 | | P07948 | LYN | Tyrosine-protein kinase Lyn | O75643 | ASCC3L1 | U5 small nuclear ribonucleoprotein 200 kDa helicase | -0.742 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O75643 | ASCC3L1 | U5 small nuclear ribonucleoprotein 200 kDa helicase | -0.745 |
| | Testosterone-propionate | hsa03060 | Protein export | 2.65E-03 | 3 | Q15070, P37108, Q15005 | OXA1L, SRP14, SPCS2 | More | | | Testosterone-propionate | hsa03430 | Mismatch repair | 4.38E-02 | 1 | P20585 | MSH3 | More | | | Testosterone-propionate | hsa03460 | Fanconi anemia pathway | 1.85E-02 | 2 | P40692, Q9UNA4 | MLH1, POLI | More | | | Testosterone-propionate | hsa04010 | MAPK signaling pathway | 4.15E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa04014 | Ras signaling pathway | 9.55E-04 | 9 | P42338, P20827, P49767, P08069, Q13009, Q7LDG7, P63218, P50151, P19174 | PIK3CB, EFNA1, VEGFC, IGF1R, TIAM1, RASGRP2, GNG5, GNG10, PLCG1 | More | | | Testosterone-propionate | hsa04015 | Rap1 signaling pathway | 9.79E-05 | 14 | P20827, P49767, P08069, P06213, Q96FS4, P11215, P25116, Q8TEU7, Q13009, O00522, Q7LDG7, P42338, P08514, P19174 | EFNA1, VEGFC, IGF1R, INSR, SIPA1, ITGAM, F2R, RAPGEF6, TIAM1, KRIT1, RASGRP2, PIK3CB, ITGA2B, PLCG1 | More | | | Testosterone-propionate | hsa04060 | Cytokine-cytokine receptor interaction | 8.46E-04 | 14 | P14784, P27930, P14778, P37173, P26842, Q06643, Q13651, P78552, P25024, Q9UBD3, P47992, P09341, P80075, P01730 | IL2RB, IL1R2, IL1R1, TGFBR2, CD27, LTB, IL10RA, IL13RA1, CXCR1, XCL2, XCL1, CXCL1, CCL8, CD4 | More | | | Testosterone-propionate | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 1.32E-02 | 6 | P09341, P25024, P47992, Q9UBD3, Q13651, P14784 | CXCL1, CXCR1, XCL1, XCL2, IL10RA, IL2RB | More | | | Testosterone-propionate | hsa04062 | Chemokine signaling pathway | 2.28E-04 | 15 | P25024, P09341, P47992, Q9UBD3, P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q08881, Q7LDG7, Q13009, Q8WYR1 | CXCR1, CXCL1, XCL1, XCL2, FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, ITK, RASGRP2, TIAM1, PIK3R5 | More | | | Testosterone-propionate | hsa04064 | NF-kappa B signaling pathway | 9.67E-09 | 22 | P10415, Q13489, O00463, Q13546, P14778, P01584, P29965, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, Q06643, Q9UNE0, Q9NQC7 | BCL2, BIRC3, TRAF5, RIPK1, IL1R1, IL1B, CD40LG, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, LTB, EDAR, CYLD | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.713 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.837 | | P06239 | LCK | Tyrosine-protein kinase Lck | O00463 | TRAF5 | TNF receptor-associated factor 5 | 0.718 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | 0.717 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | P14778 | IL1R1 | Interleukin-1 receptor type 1 | 0.76 | | P06239 | LCK | Tyrosine-protein kinase Lck | P14778 | IL1R1 | Interleukin-1 receptor type 1 | -0.782 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | P01584 | IL1B | Interleukin-1 beta | 0.799 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q04759 | PRKCQ | Protein kinase C theta type | 0.779 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q04759 | PRKCQ | Protein kinase C theta type | 0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.723 | | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | Q13077 | TRAF1 | TNF receptor-associated factor 1 | -0.73 | | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | Q16548 | BCL2A1 | Bcl-2-related protein A1 | 0.875 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q16548 | BCL2A1 | Bcl-2-related protein A1 | -0.701 | | P06239 | LCK | Tyrosine-protein kinase Lck | P07948 | LYN | Tyrosine-protein kinase Lyn | -0.701 | | P06239 | LCK | Tyrosine-protein kinase Lck | P06239 | LCK | Tyrosine-protein kinase Lck | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | Q8WV28 | BLNK | B-cell linker protein | -0.816 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q13315 | ATM | Serine-protein kinase ATM | 0.723 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | P63279 | UBE2I | SUMO-conjugating enzyme UBC9 | 0.756 | | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | P24522 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | 0.796 | | P06239 | LCK | Tyrosine-protein kinase Lck | P24522 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | -0.724 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P24522 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | -0.734 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.802 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.802 | | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.7 | | P06239 | LCK | Tyrosine-protein kinase Lck | P09341 | CXCL1 | Growth-regulated alpha protein | -0.805 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P09341 | CXCL1 | Growth-regulated alpha protein | -0.789 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q06643 | LTB | Lymphotoxin-beta | 0.846 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.825 |
| | Testosterone-propionate | hsa04066 | HIF-1 signaling pathway | 2.16E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa04068 | FoxO signaling pathway | 1.99E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa04070 | Phosphatidylinositol signaling system | 3.47E-02 | 4 | P0DP23, Q14643, P23743, P17252 | CALM1, ITPR1, DGKA, PRKCA | More | | | Testosterone-propionate | hsa04071 | Sphingolipid signaling pathway | 1.06E-04 | 8 | P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2 | PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2 | More | | | Testosterone-propionate | hsa04080 | Neuroactive ligand-receptor interaction | 1.00E-02 | 7 | P08311, Q15722, P21453, Q9H228, O00398, P21730, P07550 | CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, ADRB2 | More | | | Testosterone-propionate | hsa04110 | Cell cycle | 6.80E-03 | 6 | P06493, O75293, P30304, P33981, P42773, P01106 | CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYC | More | | | Testosterone-propionate | hsa04114 | Oocyte meiosis | 3.19E-03 | 5 | P51812, Q02750, P16298, Q17RY0, P08069 | RPS6KA3, MAP2K1, PPP3CB, CPEB4, IGF1R | More | | | Testosterone-propionate | hsa04120 | Ubiquitin mediated proteolysis | 3.44E-02 | 4 | Q14145, Q13042, P62837, Q15751 | KEAP1, CDC16, UBE2D2, HERC1 | More | | | Testosterone-propionate | hsa04122 | Sulfur relay system | 3.18E-02 | 1 | Q16762 | TST | More | | | Testosterone-propionate | hsa04140 | Autophagy - animal | 2.95E-02 | 5 | P08069, P22694, Q14643, P10415, Q04759 | IGF1R, PRKACB, ITPR1, BCL2, PRKCQ | More | | | Testosterone-propionate | hsa04141 | Protein processing in endoplasmic reticulum | 2.78E-02 | 3 | P07384, O95487, O95816 | CAPN1, SEC24B, BAG2 | More | | | Testosterone-propionate | hsa04142 | Lysosome | 1.46E-02 | 7 | P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916 | HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2 | More | | | Testosterone-propionate | hsa04144 | Endocytosis | 1.13E-03 | 14 | Q13191, P0DMV8, P11142, Q9H444, O75351, P62491, P25024, Q96B97, P43250, Q15438, Q14161, P14784, Q9UMY4, Q9Y5X3 | CBLB, HSPA1A, HSPA8, CHMP4B, VPS4B, RAB11A, CXCR1, SH3KBP1, GRK6, PSCD1, GIT2, IL2RB, SNX12, SNX5 | More | | | Testosterone-propionate | hsa04145 | Phagosome | 2.82E-04 | 9 | Q15080, P14598, Q13509, P68371, Q13488, P05164, O60603, P35443, P13765 | NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, HLA-DOB | More | | | Testosterone-propionate | hsa04150 | mTOR signaling pathway | 7.74E-03 | 4 | P08069, Q02750, Q9NQL2, P51812 | IGF1R, MAP2K1, RRAGD, RPS6KA3 | More | | | Testosterone-propionate | hsa04151 | PI3K-Akt signaling pathway | 3.02E-04 | 20 | P42338, P43657, P25116, P20827, P49767, Q13362, P08238, Q8WYR1, P62873, P63218, P50151, P16144, O15335, Q13751, O60603, P14784, P01568, P10415, P17252, P30281 | PIK3CB, P2RY5, F2R, EFNA1, VEGFC, PPP2R5C, HSP90AB1, PIK3R5, GNB1, GNG5, GNG10, ITGB4, CHAD, LAMB3, TLR2, IL2RB, IFNA21, BCL2, PRKCA, CCND3 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P35610 | SOAT1 | Sterol O-acyltransferase 1 | P42338 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | -0.813 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P42338 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.777 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | P43657 | P2RY5 | Lysophosphatidic acid receptor 6 | 0.784 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P43657 | P2RY5 | Lysophosphatidic acid receptor 6 | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | P20827 | EFNA1 | Ephrin-A1 | -0.763 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P20827 | EFNA1 | Ephrin-A1 | 0.715 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | P49767 | VEGFC | Vascular endothelial growth factor C | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P49767 | VEGFC | Vascular endothelial growth factor C | 0.743 | | P17252 | PRKCA | Protein kinase C alpha type | Q13362 | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | 0.745 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P08238 | HSP90AB1 | Heat shock protein HSP 90-beta | -0.823 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q8WYR1 | PIK3R5 | Phosphoinositide 3-kinase regulatory subunit 5 | 0.752 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P63218 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | 0.941 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | P50151 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -0.838 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P50151 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | 0.948 | | P17252 | PRKCA | Protein kinase C alpha type | P16144 | ITGB4 | Integrin beta-4 | 0.755 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | O15335 | CHAD | Chondroadherin | -0.792 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O15335 | CHAD | Chondroadherin | 0.795 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | Q13751 | LAMB3 | Laminin subunit beta-3 | -0.805 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13751 | LAMB3 | Laminin subunit beta-3 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | P14784 | IL2RB | Interleukin-2 receptor subunit beta | 0.779 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P14784 | IL2RB | Interleukin-2 receptor subunit beta | -0.835 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P30281 | CCND3 | G1/S-specific cyclin-D3 | 0.743 |
| | Testosterone-propionate | hsa04152 | AMPK signaling pathway | 2.07E-03 | 3 | P08069, Q96EB6, P36956 | IGF1R, SIRT1, SREBF1 | More | | | Testosterone-propionate | hsa04210 | Apoptosis | 4.11E-03 | 9 | Q13315, P10415, O76075, P01375, Q9NR28, P24522, Q16548, P43234, Q14643 | ATM, BCL2, DFFB, TNF, DIABLO, GADD45A, BCL2A1, CTSO, ITPR1 | More | | | Testosterone-propionate | hsa04211 | Longevity regulating pathway | 1.34E-03 | 4 | Q12778, P08069, Q9UEF7, Q96KQ7 | FOXO1, IGF1R, KL, EHMT2 | More | | | Testosterone-propionate | hsa04213 | Longevity regulating pathway - multiple species | 7.87E-04 | 6 | P08069, Q9Y4H2, Q08828, P51828, P0DMV8, Q13547 | IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HDAC1 | More | | | Testosterone-propionate | hsa04215 | Apoptosis - multiple species | 1.56E-02 | 2 | Q13489, P10415 | BIRC3, BCL2 | More | | | Testosterone-propionate | hsa04217 | Necroptosis | 7.23E-05 | 12 | P01375, P01568, P48023, Q13489, Q13546, P42224, Q14765, Q6FI13, Q99878, P10415, O43633, Q08752 | TNF, IFNA21, FASLG, BIRC3, RIPK1, STAT1, STAT4, H2AC18; H2AC19, H2AC14, BCL2, CHMP2A, PPID | More | | | Testosterone-propionate | hsa04218 | Cellular senescence | 4.79E-02 | 4 | P01106, O75293, P30304, P06493 | MYC, GADD45B, CDC25A, CDK1 | More | | | Testosterone-propionate | hsa04261 | Adrenergic signaling in cardiomyocytes | 2.84E-02 | 5 | P09493, Q13362, P0DP23, P17252, P10415 | TPM1, PPP2R5C, CALM1, PRKCA, BCL2 | More | | | Testosterone-propionate | hsa04270 | Vascular smooth muscle contraction | 6.96E-03 | 6 | P0DP23, Q08828, P51828, P35579, P35749, P35318 | CALM1, ADCY1, ADCY7, MYH9, MYH11, ADM | More | | | Testosterone-propionate | hsa04310 | Wnt signaling pathway | 1.79E-02 | 2 | P17612, P67870 | PRKACA, CSNK2B | More | | | Testosterone-propionate | hsa04330 | Notch signaling pathway | 2.77E-02 | 2 | Q92542, P49768 | NCSTN, PSEN1 | More | | | Testosterone-propionate | hsa04340 | Hedgehog signaling pathway | 1.87E-04 | 5 | P49841, P17612, P22694, Q13635, P10415 | GSK3B, PRKACA, PRKACB, PTCH1, BCL2 | More | | | Testosterone-propionate | hsa04360 | Axon guidance | 2.74E-03 | 8 | P16333, P20827, O95631, P42338, P07332, P23528, P19174, Q06124 | NCK1, EFNA1, NTN1, PIK3CB, FES, CFL1, PLCG1, PTPN11 | More | | | Testosterone-propionate | hsa04370 | VEGF signaling pathway | 2.68E-03 | 3 | P16298, Q05397, Q02750 | PPP3CB, PTK2, MAP2K1 | More | | | Testosterone-propionate | hsa04371 | Apelin signaling pathway | 1.00E-02 | 7 | P63218, P50151, Q8WYR1, Q14814, Q14344, Q13485, P84022 | GNG5, GNG10, PIK3R5, MEF2D, GNA13, SMAD4, SMAD3 | More | | | Testosterone-propionate | hsa04380 | Osteoclast differentiation | 1.02E-02 | 6 | Q9UQC2, Q16539, P14778, O75015, P01375, Q8N149 | GAB2, MAPK14, IL1R1, FCGR3B, TNF, LILRA2 | More | | | Testosterone-propionate | hsa04390 | Hippo signaling pathway | 2.08E-02 | 3 | P84022, Q13485, Q13489 | SMAD3, SMAD4, BIRC3 | More | | | Testosterone-propionate | hsa04392 | Hippo signaling pathway - multiple species | 3.01E-02 | 1 | Q6V0I7 | FAT4 | More | | | Testosterone-propionate | hsa04510 | Focal adhesion | 3.48E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa04512 | ECM-receptor interaction | 1.62E-03 | 4 | P07359, P26012, P08514, P16070 | GP1BA, ITGB8, ITGA2B, CD44 | More | | | Testosterone-propionate | hsa04514 | Cell adhesion molecules | 8.19E-03 | 3 | P16109, P56750, O00501 | SELP, CLDN17, CLDN5 | More | | | Testosterone-propionate | hsa04520 | Adherens junction | 8.29E-03 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa04530 | Tight junction | 1.64E-06 | 8 | Q8TEU7, P63261, P16989, P56750, O00501, Q9Y478, Q92974, Q14247 | RAPGEF6, ACTG1, CSDA, CLDN17, CLDN5, PRKAB1, ARHGEF2, CTTN | More | | | Testosterone-propionate | hsa04540 | Gap junction | 1.29E-02 | 4 | P17252, Q13509, P68371, Q14643 | PRKCA, TUBB3, TUBB2C, ITPR1 | More | | | Testosterone-propionate | hsa04550 | Signaling pathways regulating pluripotency of stem cells | 1.99E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa04610 | Complement and coagulation cascades | 8.72E-04 | 3 | P25116, P09871, P0C0L4 | F2R, C1S, C4A | More | | | Testosterone-propionate | hsa04611 | Platelet activation | 2.96E-06 | 7 | P25116, Q9Y490, P08514, Q15746, Q8WYR1, P17612, P07359 | F2R, TLN1, ITGA2B, MYLK, PIK3R5, PRKACA, GP1BA | More | | | Testosterone-propionate | hsa04612 | Antigen processing and presentation | 1.56E-04 | 6 | P13765, P01730, P26715, P26717, Q13241, P01732 | HLA-DOB, CD4, KLRC1, KLRC2, KLRD1, CD8A | More | | | Testosterone-propionate | hsa04613 | Neutrophil extracellular trap formation | 1.42E-06 | 23 | P17252, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, P14598, Q15080, P20160, P08311, P21730, P08514, P21462, P07359 | PRKCA, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, C5AR1, ITGA2B, FPR1, GP1BA | More | | | Testosterone-propionate | hsa04620 | Toll-like receptor signaling pathway | 4.16E-02 | 2 | Q13546, P01568 | RIPK1, IFNA21 | More | | | Testosterone-propionate | hsa04621 | NOD-like receptor signaling pathway | 4.72E-02 | 3 | P01568, Q13489, Q13546 | IFNA21, BIRC3, RIPK1 | More | | | Testosterone-propionate | hsa04622 | RIG-I-like receptor signaling pathway | 2.39E-02 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Testosterone-propionate | hsa04623 | Cytosolic DNA-sensing pathway | 9.06E-05 | 4 | P01584, P01568, Q13546, Q8NHW4 | IL1B, IFNA21, RIPK1, CCL4L2 | More | | | Testosterone-propionate | hsa04625 | C-type lectin receptor signaling pathway | 3.87E-02 | 4 | Q9ULY5, P20749, P01375, Q16539 | CLEC4E, BCL3, TNF, MAPK14 | More | | | Testosterone-propionate | hsa04640 | Hematopoietic cell lineage | 1.51E-06 | 13 | P13612, P21926, P14778, P27930, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P09564, P13765 | ITGA4, CD9, IL1R1, IL1R2, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD7, HLA-DOB | More | | | Testosterone-propionate | hsa04650 | Natural killer cell mediated cytotoxicity | 8.57E-07 | 11 | P16298, P50591, P06239, O60880, P20963, Q02750, Q13241, P26718, O14931, P26717, P26715 | PPP3CB, TNFSF10, LCK, SH2D1A, CD247, MAP2K1, KLRD1, KLRK1, NCR3, KLRC2, KLRC1 | More | | | Testosterone-propionate | hsa04657 | IL-17 signaling pathway | 2.18E-04 | 6 | O00463, Q16539, P49841, P09341, P14780, P01375 | TRAF5, MAPK14, GSK3B, CXCL1, MMP9, TNF | More | | | Testosterone-propionate | hsa04658 | Th1 and Th2 cell differentiation | 3.15E-11 | 12 | Q04759, P07766, P20963, P09693, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P13765, Q13761 | PRKCQ, CD3E, CD247, CD3G, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| P06239 | LCK | Tyrosine-protein kinase Lck | Q04759 | PRKCQ | Protein kinase C theta type | 0.779 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q04759 | PRKCQ | Protein kinase C theta type | 0.776 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P07766 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | -0.824 | | P06239 | LCK | Tyrosine-protein kinase Lck | P07766 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | 0.928 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | 0.706 | | P06239 | LCK | Tyrosine-protein kinase Lck | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | 0.927 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | 0.74 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P09693 | CD3G | T-cell surface glycoprotein CD3 gamma chain | 0.935 | | P06239 | LCK | Tyrosine-protein kinase Lck | P09693 | CD3G | T-cell surface glycoprotein CD3 gamma chain | 0.752 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P09693 | CD3G | T-cell surface glycoprotein CD3 gamma chain | 0.744 | | P06239 | LCK | Tyrosine-protein kinase Lck | P01730 | CD4 | T-cell surface glycoprotein CD4 | 0.746 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P06239 | LCK | Tyrosine-protein kinase Lck | -0.701 | | P06239 | LCK | Tyrosine-protein kinase Lck | P06239 | LCK | Tyrosine-protein kinase Lck | 1 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q14765 | STAT4 | Signal transducer and activator of transcription 4 | 0.742 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P23771 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | 0.778 | | P06239 | LCK | Tyrosine-protein kinase Lck | P23771 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | 0.77 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P23771 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | 0.85 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q9UL17 | TBX21 | T-box transcription factor TBX21 | -0.719 | | P07195 | LDHB | L-lactate dehydrogenase B chain | Q9UL17 | TBX21 | T-box transcription factor TBX21 | 0.786 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q9UL17 | TBX21 | T-box transcription factor TBX21 | 0.866 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q9UL17 | TBX21 | T-box transcription factor TBX21 | 0.735 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P14784 | IL2RB | Interleukin-2 receptor subunit beta | -0.771 | | P06239 | LCK | Tyrosine-protein kinase Lck | P14784 | IL2RB | Interleukin-2 receptor subunit beta | 0.727 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.733 | | P06239 | LCK | Tyrosine-protein kinase Lck | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.777 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.795 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q13761 | RUNX3 | Runt-related transcription factor 3 | -0.855 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q13761 | RUNX3 | Runt-related transcription factor 3 | 0.85 |
| | Testosterone-propionate | hsa04659 | Th17 cell differentiation | 2.71E-11 | 16 | P25963, Q04759, P19174, P01730, P06239, P14784, P13765, P14778, Q9UL17, P23771, P84022, Q13485, P08238, P07766, P09693, P20963 | NFKBIA, PRKCQ, PLCG1, CD4, LCK, IL2RB, HLA-DOB, IL1R1, TBX21, GATA3, SMAD3, SMAD4, HSP90AB1, CD3E, CD3G, CD247 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| O75469 | NR1I2 | Nuclear receptor subfamily 1 group I member 2 | P25963 | NFKBIA | NF-kappa-B inhibitor alpha | -0.728 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q04759 | PRKCQ | Protein kinase C theta type | 0.779 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q04759 | PRKCQ | Protein kinase C theta type | 0.776 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P19174 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | -0.766 | | P06239 | LCK | Tyrosine-protein kinase Lck | P01730 | CD4 | T-cell surface glycoprotein CD4 | 0.746 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P06239 | LCK | Tyrosine-protein kinase Lck | -0.701 | | P06239 | LCK | Tyrosine-protein kinase Lck | P06239 | LCK | Tyrosine-protein kinase Lck | 1 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P14784 | IL2RB | Interleukin-2 receptor subunit beta | -0.771 | | P06239 | LCK | Tyrosine-protein kinase Lck | P14784 | IL2RB | Interleukin-2 receptor subunit beta | 0.727 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P14784 | IL2RB | Interleukin-2 receptor subunit beta | -0.835 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.733 | | P06239 | LCK | Tyrosine-protein kinase Lck | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.777 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.795 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P14778 | IL1R1 | Interleukin-1 receptor type 1 | 0.714 | | P06239 | LCK | Tyrosine-protein kinase Lck | P14778 | IL1R1 | Interleukin-1 receptor type 1 | -0.782 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P14778 | IL1R1 | Interleukin-1 receptor type 1 | 0.764 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q9UL17 | TBX21 | T-box transcription factor TBX21 | -0.719 | | P07195 | LDHB | L-lactate dehydrogenase B chain | Q9UL17 | TBX21 | T-box transcription factor TBX21 | 0.786 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q9UL17 | TBX21 | T-box transcription factor TBX21 | 0.866 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | Q9UL17 | TBX21 | T-box transcription factor TBX21 | 0.735 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P23771 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | 0.778 | | P06239 | LCK | Tyrosine-protein kinase Lck | P23771 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | 0.77 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P23771 | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 | 0.85 | | O75469 | NR1I2 | Nuclear receptor subfamily 1 group I member 2 | P84022 | SMAD3 | Mothers against decapentaplegic homolog 3 | 0.769 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P84022 | SMAD3 | Mothers against decapentaplegic homolog 3 | 0.725 | | O75469 | NR1I2 | Nuclear receptor subfamily 1 group I member 2 | Q13485 | SMAD4 | Mothers against decapentaplegic homolog 4 | -0.721 | | P07948 | LYN | Tyrosine-protein kinase Lyn | Q13485 | SMAD4 | Mothers against decapentaplegic homolog 4 | -0.729 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13485 | SMAD4 | Mothers against decapentaplegic homolog 4 | -0.746 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P08238 | HSP90AB1 | Heat shock protein HSP 90-beta | -0.782 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P08238 | HSP90AB1 | Heat shock protein HSP 90-beta | -0.823 | | P07948 | LYN | Tyrosine-protein kinase Lyn | P07766 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | -0.824 | | P06239 | LCK | Tyrosine-protein kinase Lck | P07766 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | 0.928 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P07766 | CD3E | T-cell surface glycoprotein CD3 epsilon chain | -0.838 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P09693 | CD3G | T-cell surface glycoprotein CD3 gamma chain | 0.935 | | P06239 | LCK | Tyrosine-protein kinase Lck | P09693 | CD3G | T-cell surface glycoprotein CD3 gamma chain | 0.752 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P09693 | CD3G | T-cell surface glycoprotein CD3 gamma chain | 0.744 | | P07195 | LDHB | L-lactate dehydrogenase B chain | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | 0.706 | | P06239 | LCK | Tyrosine-protein kinase Lck | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | 0.927 | | P42330 | AKR1C3 | Aldo-keto reductase family 1 member C3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | 0.74 |
| | Testosterone-propionate | hsa04660 | T cell receptor signaling pathway | 1.83E-06 | 12 | Q9UDY8, Q04759, P10747, O95267, Q08881, P07766, P20963, P09693, P01730, P01732, Q13191, P06239 | MALT1, PRKCQ, CD28, RASGRP1, ITK, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK | More | | | Testosterone-propionate | hsa04662 | B cell receptor signaling pathway | 1.21E-05 | 5 | P42338, P60033, P07948, P21854, Q8N149 | PIK3CB, CD81, LYN, CD72, LILRA2 | More | | | Testosterone-propionate | hsa04664 | Fc epsilon RI signaling pathway | 1.36E-04 | 7 | P01375, Q16539, P42338, Q9UQC2, P07948, P19174, P09917 | TNF, MAPK14, PIK3CB, GAB2, LYN, PLCG1, ALOX5 | More | | | Testosterone-propionate | hsa04668 | TNF signaling pathway | 2.21E-02 | 5 | P01375, O00463, Q16539, P20749, P14780 | TNF, TRAF5, MAPK14, BCL3, MMP9 | More | | | Testosterone-propionate | hsa04672 | Intestinal immune network for IgA production | 3.36E-04 | 4 | P29965, P10747, P13765, P13612 | CD40LG, CD28, HLA-DOB, ITGA4 | More | | | Testosterone-propionate | hsa04713 | Circadian entrainment | 2.60E-02 | 4 | P0DP23, P17252, P62873, Q14643 | CALM1, PRKCA, GNB1, ITPR1 | More | | | Testosterone-propionate | hsa04714 | Thermogenesis | 1.25E-02 | 3 | P15336, P63261, Q9Y478 | ATF2, ACTG1, PRKAB1 | More | | | Testosterone-propionate | hsa04720 | Long-term potentiation | 1.95E-03 | 6 | P17252, P16298, P0DP23, P51812, Q02750, Q14643 | PRKCA, PPP3CB, CALM1, RPS6KA3, MAP2K1, ITPR1 | More | | | Testosterone-propionate | hsa04722 | Neurotrophin signaling pathway | 3.27E-02 | 3 | P49841, O43524, P48023 | GSK3B, FOXO3, FASLG | More | | | Testosterone-propionate | hsa04723 | Retrograde endocannabinoid signaling | 1.88E-02 | 4 | Q14643, P17252, P62873, Q16718 | ITPR1, PRKCA, GNB1, NDUFA5 | More | | | Testosterone-propionate | hsa04724 | Glutamatergic synapse | 1.82E-03 | 5 | O15399, P43003, P63218, P50151, P15104 | GRIN2D, SLC1A3, GNG5, GNG10, GLUL | More | | | Testosterone-propionate | hsa04725 | Cholinergic synapse | 1.88E-02 | 4 | Q14643, P17252, P62873, P10415 | ITPR1, PRKCA, GNB1, BCL2 | More | | | Testosterone-propionate | hsa04727 | GABAergic synapse | 4.42E-02 | 3 | P63218, P50151, P15104 | GNG5, GNG10, GLUL | More | | | Testosterone-propionate | hsa04728 | Dopaminergic synapse | 3.55E-02 | 5 | Q14643, P17252, P62873, Q13362, P0DP23 | ITPR1, PRKCA, GNB1, PPP2R5C, CALM1 | More | | | Testosterone-propionate | hsa04730 | Long-term depression | 1.16E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa04742 | Taste transduction | 3.91E-02 | 1 | P17612 | PRKACA | More | | | Testosterone-propionate | hsa04744 | Phototransduction | 1.02E-02 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | | | Testosterone-propionate | hsa04750 | Inflammatory mediator regulation of TRP channels | 4.01E-02 | 4 | P01584, Q08828, P51828, P0DP23 | IL1B, ADCY1, ADCY7, CALM1 | More | | | Testosterone-propionate | hsa04810 | Regulation of actin cytoskeleton | 2.58E-02 | 3 | Q15746, P08514, P25116 | MYLK, ITGA2B, F2R | More | | | Testosterone-propionate | hsa04910 | Insulin signaling pathway | 2.35E-02 | 3 | P22694, P06737, P49841 | PRKACB, PYGL, GSK3B | More | | | Testosterone-propionate | hsa04912 | GnRH signaling pathway | 3.89E-02 | 3 | P17252, Q14643, P0DP23 | PRKCA, ITPR1, CALM1 | More | | | Testosterone-propionate | hsa04913 | Ovarian steroidogenesis | 8.40E-04 | 2 | P06213, P08069 | INSR, IGF1R | More | | | Testosterone-propionate | hsa04914 | Progesterone-mediated oocyte maturation | 5.89E-03 | 4 | P08069, Q17RY0, P51812, Q02750 | IGF1R, CPEB4, RPS6KA3, MAP2K1 | More | | | Testosterone-propionate | hsa04915 | Estrogen signaling pathway | 3.17E-02 | 5 | Q08828, P51828, P0DMV8, P0DP23, Q15788 | ADCY1, ADCY7, HSPA1A, CALM1, NCOA1 | More | | | Testosterone-propionate | hsa04919 | Thyroid hormone signaling pathway | 7.11E-03 | 4 | P49841, P22694, O60244, Q9NVC6 | GSK3B, PRKACB, MED14, MED17 | More | | | Testosterone-propionate | hsa04920 | Adipocytokine signaling pathway | 2.80E-02 | 2 | Q06124, Q9Y478 | PTPN11, PRKAB1 | More | | | Testosterone-propionate | hsa04922 | Glucagon signaling pathway | 7.76E-04 | 7 | P14618, P22694, P06737, Q12778, Q13370, P0DP23, Q14643 | PKM2, PRKACB, PYGL, FOXO1, PDE3B, CALM1, ITPR1 | More | | | Testosterone-propionate | hsa04923 | Regulation of lipolysis in adipocytes | 3.76E-02 | 1 | P06213 | INSR | More | | | Testosterone-propionate | hsa04924 | Renin secretion | 1.79E-04 | 5 | P22694, P07550, Q14643, Q13370, P0DP23 | PRKACB, ADRB2, ITPR1, PDE3B, CALM1 | More | | | Testosterone-propionate | hsa04928 | Parathyroid hormone synthesis, secretion and action | 4.23E-02 | 4 | Q14643, P22694, P23771, P10415 | ITPR1, PRKACB, GATA3, BCL2 | More | | | Testosterone-propionate | hsa04930 | Type II diabetes mellitus | 3.14E-02 | 1 | P06213 | INSR | More | | | Testosterone-propionate | hsa04931 | Insulin resistance | 1.94E-02 | 3 | P01375, P49841, P06737 | TNF, GSK3B, PYGL | More | | | Testosterone-propionate | hsa04932 | Non-alcoholic fatty liver disease | 7.56E-04 | 9 | P01375, P49841, O43521, P48023, O75460, P01584, P13073, P12074, O95298 | TNF, GSK3B, BCL2L11, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFC2 | More | | | Testosterone-propionate | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 8.03E-05 | 9 | P84022, Q13485, P42224, P10415, P42338, Q12778, P49767, P17252, P19174 | SMAD3, SMAD4, STAT1, BCL2, PIK3CB, FOXO1, VEGFC, PRKCA, PLCG1 | More | | | Testosterone-propionate | hsa04940 | Type I diabetes mellitus | 1.87E-02 | 2 | P48023, P01375 | FASLG, TNF | More | | | Testosterone-propionate | hsa04960 | Aldosterone-regulated sodium reabsorption | 3.14E-02 | 1 | P06213 | INSR | More | | | Testosterone-propionate | hsa04964 | Proximal tubule bicarbonate reclamation | 4.03E-03 | 2 | P00918, P49448 | CA2, GLUD2 | More | | | Testosterone-propionate | hsa04966 | Collecting duct acid secretion | 1.95E-03 | 3 | Q13488, P00918, Q9Y666 | TCIRG1, CA2, SLC12A7 | More | | | Testosterone-propionate | hsa04970 | Salivary secretion | 4.78E-02 | 3 | Q08828, P51828, P0DP23 | ADCY1, ADCY7, CALM1 | More | | | Testosterone-propionate | hsa04975 | Fat digestion and absorption | 9.50E-04 | 1 | O14494 | PLPP1 | More | | | Testosterone-propionate | hsa04976 | Bile secretion | 2.51E-03 | 5 | Q08828, P51828, P22694, P08183, Q14032 | ADCY1, ADCY7, PRKACB, ABCB1, BAAT | More | | | Testosterone-propionate | hsa05010 | Alzheimer disease | 3.55E-02 | 7 | Q16718, O14521, Q14643, P0DP23, Q13509, P68371, Q08752 | NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2C, PPID | More | | | Testosterone-propionate | hsa05012 | Parkinson disease | 2.25E-02 | 6 | Q16718, O14521, Q14643, P0DP23, Q13509, P68371 | NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2C | More | | | Testosterone-propionate | hsa05016 | Huntington disease | 2.46E-02 | 9 | O95298, P13073, P12074, P24928, P30876, P62487, O75460, P28070, O00232 | NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, ERN1, PSMB4, PSMD12 | More | | | Testosterone-propionate | hsa05017 | Spinocerebellar ataxia | 2.22E-02 | 4 | Q92915, O15399, P42338, P21796 | FGF14, GRIN2D, PIK3CB, VDAC1 | More | | | Testosterone-propionate | hsa05020 | Prion disease | 1.15E-02 | 7 | Q16718, O14521, Q14643, Q13509, P68371, P14598, Q15080 | NDUFA5, SDHD, ITPR1, TUBB3, TUBB2C, NCF1, NCF4 | More | | | Testosterone-propionate | hsa05022 | Pathways of neurodegeneration - multiple diseases | 4.00E-03 | 12 | Q14643, Q13509, P68371, P10415, Q16718, O14521, Q06055, Q13561, P17252, Q08752, O15020, P0DP23 | ITPR1, TUBB3, TUBB2C, BCL2, NDUFA5, SDHD, ATP5G2, DCTN2, PRKCA, PPID, SPTBN2, CALM1 | More | | | Testosterone-propionate | hsa05034 | Alcoholism | 2.05E-05 | 7 | Q13547, Q93077, P58876, P62807, Q16778, O60814, P68431 | HDAC1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | | Testosterone-propionate | hsa05110 | Vibrio cholerae infection | 2.11E-03 | 2 | Q99437, P17612 | ATP6V0B, PRKACA | More | | | Testosterone-propionate | hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 2.45E-02 | 4 | Q16539, P09341, P25024, P25025 | MAPK14, CXCL1, CXCR1, CXCR2 | More | | | Testosterone-propionate | hsa05130 | Pathogenic Escherichia coli infection | 2.02E-04 | 8 | Q14247, P56750, O00501, Q92974, P63261, P25116, Q06124, O95487 | CTTN, CLDN17, CLDN5, ARHGEF2, ACTG1, F2R, PTPN11, SEC24B | More | | | Testosterone-propionate | hsa05131 | Shigellosis | 2.27E-02 | 8 | P68431, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID | More | | | Testosterone-propionate | hsa05132 | Salmonella infection | 3.94E-05 | 11 | P25963, Q9UJU2, Q13546, Q13489, P10415, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371 | NFKBIA, LEF1, RIPK1, BIRC3, BCL2, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2C | More | | | Testosterone-propionate | hsa05133 | Pertussis | 1.58E-03 | 3 | P09871, P0C0L4, Q02556 | C1S, C4A, IRF8 | More | | | Testosterone-propionate | hsa05134 | Legionellosis | 2.82E-02 | 3 | P01584, Q9NR31, P0DMV8 | IL1B, SAR1A, HSPA1A | More | | | Testosterone-propionate | hsa05140 | Leishmaniasis | 2.04E-04 | 9 | O75015, P14598, P42224, P13765, O60603, P29350, P49006, Q16539, Q15080 | FCGR3B, NCF1, STAT1, HLA-DOB, TLR2, PTPN6, MARCKSL1, MAPK14, NCF4 | More | | | Testosterone-propionate | hsa05143 | African trypanosomiasis | 2.72E-02 | 2 | P01375, P48023 | TNF, FASLG | More | | | Testosterone-propionate | hsa05145 | Toxoplasmosis | 1.02E-03 | 7 | P25963, P10415, Q13489, P42224, P13765, O60603, P29965 | NFKBIA, BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LG | More | | | Testosterone-propionate | hsa05146 | Amoebiasis | 1.32E-03 | 7 | P09341, P14778, P27930, O60603, P05089, P12814, P08311 | CXCL1, IL1R1, IL1R2, TLR2, ARG1, ACTN1, CTSG | More | | | Testosterone-propionate | hsa05150 | Staphylococcus aureus infection | 1.31E-02 | 2 | P0C0L4, P13646 | C4A, KRT13 | More | | | Testosterone-propionate | hsa05152 | Tuberculosis | 7.93E-04 | 8 | Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8 | TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1 | More | | | Testosterone-propionate | hsa05160 | Hepatitis C | 1.27E-02 | 4 | P60033, P49841, P01375, P48023 | CD81, GSK3B, TNF, FASLG | More | | | Testosterone-propionate | hsa05161 | Hepatitis B | 8.49E-03 | 4 | P25963, Q13485, P10415, P84022 | NFKBIA, SMAD4, BCL2, SMAD3 | More | | | Testosterone-propionate | hsa05162 | Measles | 3.18E-02 | 4 | P23458, P0DMV8, P01584, Q9NP90 | JAK1, HSPA1A, IL1B, RAB9B | More | | | Testosterone-propionate | hsa05163 | Human cytomegalovirus infection | 2.84E-04 | 15 | P01375, Q14643, P0DP23, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, P04637, O00463 | TNF, ITPR1, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, TP53, TRAF5 | More | | | Testosterone-propionate | hsa05165 | Human papillomavirus infection | 3.10E-02 | 8 | P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315 | ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATM | More | | | Testosterone-propionate | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 3.04E-03 | 10 | P01568, P42224, P62873, P62879, P16298, Q14643, Q02750, P0DP23, P0CG47, Q9UJU2 | IFNA21, STAT1, GNB1, GNB2, PPP3CB, ITPR1, MAP2K1, CALM1, UBB, LEF1 | More | | | Testosterone-propionate | hsa05169 | Epstein-Barr virus infection | 5.02E-04 | 12 | P20023, P13765, P01106, Q13547, Q92769, O00463, P07948, Q13761, P24522, P07766, P09693, P20963 | CR2, HLA-DOB, MYC, HDAC1, HDAC2, TRAF5, LYN, RUNX3, GADD45A, CD3E, CD3G, CD247 | More | | | Testosterone-propionate | hsa05170 | Human immunodeficiency virus 1 infection | 8.44E-05 | 14 | Q02750, P62873, P62879, P16298, P0DP23, Q05397, P17252, Q14643, P01568, O60603, Q13315, P10415, Q9Y6Q5, P20333 | MAP2K1, GNB1, GNB2, PPP3CB, CALM1, PTK2, PRKCA, ITPR1, IFNA21, TLR2, ATM, BCL2, AP1M2, TNFRSF1B | More | | | Testosterone-propionate | hsa05200 | Pathways in cancer | 1.55E-03 | 28 | Q13751, P42338, P08238, P42224, P19174, Q9UJU2, P17252, P43246, P84022, Q13485, Q13547, P14923, P30281, P10415, Q13489, P49767, Q12778, P43657, P25116, P62873, P63218, P50151, Q14344, Q7LDG7, O75293, P0DP23, P01568, P14784 | LAMB3, PIK3CB, HSP90AB1, STAT1, PLCG1, LEF1, PRKCA, MSH2, SMAD3, SMAD4, HDAC1, JUP, CCND3, BCL2, BIRC3, VEGFC, FOXO1, P2RY5, F2R, GNB1, GNG5, GNG10, GNA13, RASGRP2, GADD45B, CALM1, IFNA21, IL2RB | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13751 | LAMB3 | Laminin subunit beta-3 | 0.844 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P42338 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 0.777 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P08238 | HSP90AB1 | Heat shock protein HSP 90-beta | -0.823 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P19174 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | -0.766 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P43246 | MSH2 | DNA mismatch repair protein Msh2 | -0.811 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P84022 | SMAD3 | Mothers against decapentaplegic homolog 3 | 0.725 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13485 | SMAD4 | Mothers against decapentaplegic homolog 4 | -0.746 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13547 | HDAC1 | Histone deacetylase 1 | -0.754 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P30281 | CCND3 | G1/S-specific cyclin-D3 | 0.743 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P49767 | VEGFC | Vascular endothelial growth factor C | 0.743 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P43657 | P2RY5 | Lysophosphatidic acid receptor 6 | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P63218 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | 0.941 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P50151 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | 0.948 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q14344 | GNA13 | Guanine nucleotide-binding protein subunit alpha-13 | 0.87 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q7LDG7 | RASGRP2 | RAS guanyl-releasing protein 2 | 0.704 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O75293 | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P14784 | IL2RB | Interleukin-2 receptor subunit beta | -0.835 |
| | Testosterone-propionate | hsa05202 | Transcriptional misregulation in cancer | 2.13E-04 | 14 | Q12778, Q13315, P14780, P27930, Q16548, P11215, O15550, P08069, P05164, P08246, Q9C0K0, Q13547, P12980, P24522 | FOXO1, ATM, MMP9, IL1R2, BCL2A1, ITGAM, UTX, IGF1R, MPO, ELA2, BCL11B, HDAC1, LYL1, GADD45A | More | | | Testosterone-propionate | hsa05203 | Viral carcinogenesis | 1.22E-03 | 6 | Q13547, Q15283, P58876, P62807, Q16778, O60814 | HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12 | More | | | Testosterone-propionate | hsa05204 | Chemical carcinogenesis | 1.48E-02 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Testosterone-propionate | hsa05205 | Proteoglycans in cancer | 3.48E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa05210 | Colorectal cancer | 1.49E-03 | 5 | Q9UKG1, P84022, Q13485, P10415, P37173 | APPL1, SMAD3, SMAD4, BCL2, TGFBR2 | More | | | Testosterone-propionate | hsa05211 | Renal cell carcinoma | 1.06E-02 | 2 | Q06124, Q99814 | PTPN11, EPAS1 | More | | | Testosterone-propionate | hsa05212 | Pancreatic cancer | 4.45E-03 | 4 | P42338, P84022, Q13485, O75293 | PIK3CB, SMAD3, SMAD4, GADD45B | More | | | Testosterone-propionate | hsa05213 | Endometrial cancer | 3.79E-02 | 2 | O15169, Q02750 | AXIN1, MAP2K1 | More | | | Testosterone-propionate | hsa05214 | Glioma | 9.95E-03 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa05215 | Prostate cancer | 1.33E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa05216 | Thyroid cancer | 3.80E-02 | 2 | P01106, O75293 | MYC, GADD45B | More | | | Testosterone-propionate | hsa05217 | Basal cell carcinoma | 2.83E-02 | 3 | Q13635, Q9UJU2, P24522 | PTCH1, LEF1, GADD45A | More | | | Testosterone-propionate | hsa05218 | Melanoma | 6.63E-03 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa05219 | Bladder cancer | 4.07E-02 | 2 | P14780, P04637 | MMP9, TP53 | More | | | Testosterone-propionate | hsa05220 | Chronic myeloid leukemia | 1.44E-03 | 6 | Q13547, Q13485, P25963, P84022, P42338, O75293 | HDAC1, SMAD4, NFKBIA, SMAD3, PIK3CB, GADD45B | More | | | Testosterone-propionate | hsa05222 | Small cell lung cancer | 1.50E-02 | 3 | Q13489, P10415, P25963 | BIRC3, BCL2, NFKBIA | More | | | Testosterone-propionate | hsa05223 | Non-small cell lung cancer | 1.39E-02 | 3 | P10826, Q9HC35, O75293 | RARB, EML4, GADD45B | More | | | Testosterone-propionate | hsa05224 | Breast cancer | 1.24E-02 | 5 | P08069, P49841, Q92837, P04637, P24522 | IGF1R, GSK3B, FRAT1, TP53, GADD45A | More | | | Testosterone-propionate | hsa05225 | Hepatocellular carcinoma | 1.33E-02 | 1 | P08069 | IGF1R | More | | | Testosterone-propionate | hsa05226 | Gastric cancer | 4.33E-03 | 5 | Q02750, O15169, P84022, Q13485, P10415 | MAP2K1, AXIN1, SMAD3, SMAD4, BCL2 | More | | | Testosterone-propionate | hsa05230 | Central carbon metabolism in cancer | 1.12E-02 | 1 | P11413 | G6PD | More | | | Testosterone-propionate | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 5.72E-06 | 11 | O95267, P07766, P20963, P09693, P06239, O60603, P10747, Q04759, Q16539, Q9HC35, P01730 | RASGRP1, CD3E, CD247, CD3G, LCK, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4 | More | | | Testosterone-propionate | hsa05320 | Autoimmune thyroid disease | 1.27E-03 | 4 | P13765, P29965, P01568, P10747 | HLA-DOB, CD40LG, IFNA21, CD28 | More | | | Testosterone-propionate | hsa05321 | Inflammatory bowel disease | 1.44E-04 | 5 | O60603, P13765, Q14765, Q9UL17, P23771 | TLR2, HLA-DOB, STAT4, TBX21, GATA3 | More | | | Testosterone-propionate | hsa05322 | Systemic lupus erythematosus | 2.33E-07 | 12 | P08246, P09871, P10747, P13765, P29965, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431 | ELA2, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | | Testosterone-propionate | hsa05323 | Rheumatoid arthritis | 5.16E-04 | 5 | P13765, Q13488, P10747, P09341, O60603 | HLA-DOB, TCIRG1, CD28, CXCL1, TLR2 | More | | | Testosterone-propionate | hsa05330 | Allograft rejection | 1.04E-03 | 5 | P13765, P29965, P48023, P10747, P01375 | HLA-DOB, CD40LG, FASLG, CD28, TNF | More | | | Testosterone-propionate | hsa05332 | Graft-versus-host disease | 1.95E-06 | 6 | P13765, P48023, P10747, P01375, P26715, Q13241 | HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1 | More | | | Testosterone-propionate | hsa05340 | Primary immunodeficiency | 1.31E-04 | 5 | P01730, P01732, P11912, P07766, P06239 | CD4, CD8A, CD79A, CD3E, LCK | More | | | Testosterone-propionate | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.48E-02 | 1 | P54284 | CACNB3 | More | | | Testosterone-propionate | hsa05414 | Dilated cardiomyopathy | 4.55E-02 | 2 | P54284, P26678 | CACNB3, PLN | More | | | Testosterone-propionate | hsa05415 | Diabetic cardiomyopathy | 3.09E-03 | 8 | P17252, P30405, P14598, Q15080, Q16718, O14521, P37173, P11413 | PRKCA, PPIF, NCF1, NCF4, NDUFA5, SDHD, TGFBR2, G6PD | More | | | Testosterone-propionate | hsa05416 | Viral myocarditis | 2.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | | | Testosterone-propionate | hsa05418 | Fluid shear stress and atherosclerosis | 1.26E-04 | 8 | Q16539, Q14145, P10599, P14780, P01375, P04637, P14778, P27930 | MAPK14, KEAP1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2 | More | |
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