| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Telotristat-ethyl | hsa00630 | Glyoxylate and dicarboxylate metabolism | 5.34E-03 | 2 | P40925, P15104 | MDH1, GLUL | More | | | Telotristat-ethyl | hsa03010 | Ribosome | 1.03E-02 | 2 | P46777, P50914 | RPL5, RPL14 | More | | | Telotristat-ethyl | hsa03040 | Spliceosome | 4.19E-02 | 5 | Q14562, O60508, P08579, Q01130, O43447 | DHX8, CDC40, SNRPB2, SFRS2, PPIH | More | | | Telotristat-ethyl | hsa03050 | Proteasome | 4.83E-02 | 1 | P55036 | PSMD4 | More | | | Telotristat-ethyl | hsa04142 | Lysosome | 3.31E-02 | 3 | P43234, Q9UBR2, P34059 | CTSO, CTSZ, GALNS | More | | | Telotristat-ethyl | hsa04612 | Antigen processing and presentation | 4.78E-02 | 6 | P48382, P26715, P26717, Q13241, O43908, P01375 | RFX5, KLRC1, KLRC2, KLRD1, KLRC4, TNF | More | | | Telotristat-ethyl | hsa04621 | NOD-like receptor signaling pathway | 2.27E-02 | 9 | Q9H1Y0, P43490, O00463, Q05823, P01375, P49913, P59665, P59666, P12838 | ATG5, PBEF1, TRAF5, RNASEL, TNF, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4 | More | | | Telotristat-ethyl | hsa04630 | JAK-STAT signaling pathway | 1.44E-02 | 4 | P01106, Q09472, P48551, P16871 | MYC, EP300, IFNAR2, IL7R | More | | | Telotristat-ethyl | hsa04640 | Hematopoietic cell lineage | 1.67E-02 | 4 | P20023, P11836, P09693, P16871 | CR2, MS4A1, CD3G, IL7R | More | | | Telotristat-ethyl | hsa04650 | Natural killer cell mediated cytotoxicity | 1.25E-02 | 8 | P01375, O60880, P20963, Q13241, P26718, O75015, P26717, P26715 | TNF, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1 | More | | | Telotristat-ethyl | hsa04662 | B cell receptor signaling pathway | 1.49E-03 | 5 | P42338, P60033, P07948, P21854, Q8N149 | PIK3CB, CD81, LYN, CD72, LILRA2 | More | | | Telotristat-ethyl | hsa04664 | Fc epsilon RI signaling pathway | 2.32E-02 | 3 | P42338, P07948, P09917 | PIK3CB, LYN, ALOX5 | More | | | Telotristat-ethyl | hsa04724 | Glutamatergic synapse | 5.94E-03 | 4 | O15399, P63218, P50151, P15104 | GRIN2D, GNG5, GNG10, GLUL | More | | | Telotristat-ethyl | hsa04725 | Cholinergic synapse | 4.10E-02 | 3 | P63218, P50151, P42338 | GNG5, GNG10, PIK3CB | More | | | Telotristat-ethyl | hsa04727 | GABAergic synapse | 1.63E-02 | 3 | P63218, P50151, P15104 | GNG5, GNG10, GLUL | More | | | Telotristat-ethyl | hsa04919 | Thyroid hormone signaling pathway | 4.44E-02 | 3 | P60709, Q09472, P01106 | ACTB, EP300, MYC | More | | | Telotristat-ethyl | hsa04926 | Relaxin signaling pathway | 5.70E-03 | 5 | P42338, P63218, P50151, P49767, P49407 | PIK3CB, GNG5, GNG10, VEGFC, ARRB1 | More | | | Telotristat-ethyl | hsa04929 | GnRH secretion | 4.62E-02 | 2 | P42338, P49407 | PIK3CB, ARRB1 | More | | | Telotristat-ethyl | hsa05144 | Malaria | 3.12E-02 | 4 | P60033, P01375, P35443, P26718 | CD81, TNF, THBS4, KLRK1 | More | | | Telotristat-ethyl | hsa05150 | Staphylococcus aureus infection | 1.02E-03 | 7 | P21730, P21462, O75015, P59665, P59666, P12838, P49913 | C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMP | More | | | Telotristat-ethyl | hsa05164 | Influenza A | 8.62E-03 | 4 | Q09472, P48551, P29728, P60709 | EP300, IFNAR2, OAS2, ACTB | More | | | Telotristat-ethyl | hsa05169 | Epstein-Barr virus infection | 1.83E-03 | 11 | P20023, P01106, Q13547, P42338, P07948, Q13761, O75293, P48551, P29728, P07766, P09693 | CR2, MYC, HDAC1, PIK3CB, LYN, RUNX3, GADD45B, IFNAR2, OAS2, CD3E, CD3G | More | | | Telotristat-ethyl | hsa05171 | Coronavirus disease - COVID-19 | 1.93E-02 | 4 | P48551, P29728, P46777, P50914 | IFNAR2, OAS2, RPL5, RPL14 | More | | | Telotristat-ethyl | hsa05211 | Renal cell carcinoma | 1.67E-02 | 2 | Q09472, Q99814 | EP300, EPAS1 | More | |
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