PharmaCoNets of Sodium-tetradecyl-sulfate (SPCN: 1.00 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Sodium-tetradecyl-sulfatehsa00630Glyoxylate and dicarboxylate metabolism1.29E-022P40925, P15104MDH1, GLULMore
Sodium-tetradecyl-sulfatehsa00970Aminoacyl-tRNA biosynthesis5.32E-033O95363, P54136, Q15046FARS2, RARS1, KARSMore
Sodium-tetradecyl-sulfatehsa00983Drug metabolism - other enzymes2.91E-023P04183, P32320, P05164TK1, CDA, MPOMore
Sodium-tetradecyl-sulfatehsa03040Spliceosome1.26E-026P17844, P51991, P61978, Q15365, Q01130, P11142DDX5, HNRPA3, HNRPK, PCBP1, SFRS2, HSPA8More
Sodium-tetradecyl-sulfatehsa03060Protein export3.37E-022P37108, Q15005SRP14, SPCS2More
Sodium-tetradecyl-sulfatehsa04060Cytokine-cytokine receptor interaction1.28E-0210P14784, P27930, P14778, P26842, Q06643, Q13651, P25024, P09341, P19875, P01730IL2RB, IL1R2, IL1R1, CD27, LTB, IL10RA, CXCR1, CXCL1, CXCL2, CD4More
Sodium-tetradecyl-sulfatehsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, Q13651, P14784CXCL1, CXCL2, CXCR1, IL10RA, IL2RBMore
Sodium-tetradecyl-sulfatehsa04062Chemokine signaling pathway5.37E-039P25024, P09341, P19875, P07948, P42338, P19174, P63218, P50151, P43250CXCR1, CXCL1, CXCL2, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6More
Sodium-tetradecyl-sulfatehsa04064NF-kappa B signaling pathway2.03E-0415P10415, O00463, P14778, P01375, P19174, Q04759, Q9UDY8, Q16548, P07948, P06239, P24522, O75293, P09341, P19875, Q06643BCL2, TRAF5, IL1R1, TNF, PLCG1, PRKCQ, MALT1, BCL2A1, LYN, LCK, GADD45A, GADD45B, CXCL1, CXCL2, LTBMore
Sodium-tetradecyl-sulfatehsa04071Sphingolipid signaling pathway2.25E-025P21453, Q9H228, P01375, Q13362, P10415S1PR1, EDG8, TNF, PPP2R5C, BCL2More
Sodium-tetradecyl-sulfatehsa04080Neuroactive ligand-receptor interaction6.23E-038P08311, Q15722, P21453, Q9H228, O00398, P21462, P21730, Q16581CTSG, LTB4R, S1PR1, EDG8, P2RY10, FPR1, C5AR1, C3AR1More
Sodium-tetradecyl-sulfatehsa04141Protein processing in endoplasmic reticulum6.04E-038P18848, Q15437, Q99941, O75460, P11142, Q9H3Z4, P07900, Q9NR31ATF4, SEC23B, CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1, SAR1AMore
Sodium-tetradecyl-sulfatehsa04145Phagosome2.35E-026Q15080, P05164, P78380, O60603, P35443, P13765NCF4, MPO, OLR1, TLR2, THBS4, HLA-DOBMore
Sodium-tetradecyl-sulfatehsa04151PI3K-Akt signaling pathway9.80E-0310O43521, P27348, Q13362, P07900, P22105, P23458, Q99941, P18848, O00141, Q6ZUJ8BCL2L11, YWHAQ, PPP2R5C, HSP90AA1, TNXB, JAK1, CREBL1, ATF4, SGK, PIK3AP1More
Sodium-tetradecyl-sulfatehsa04210Apoptosis2.59E-028P10415, O76075, P01375, P24522, Q16548, P43234, P18848, Q14643BCL2, DFFB, TNF, GADD45A, BCL2A1, CTSO, ATF4, ITPR1More
Sodium-tetradecyl-sulfatehsa04211Longevity regulating pathway4.57E-024P51828, Q99941, P18848, Q96RR4ADCY7, CREBL1, ATF4, CAMKK2More
Sodium-tetradecyl-sulfatehsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Sodium-tetradecyl-sulfatehsa04217Necroptosis5.00E-037P23458, Q9NQC7, P07900, P05141, P01584, Q9H444, O75351JAK1, CYLD, HSP90AA1, SLC25A5, IL1B, CHMP4B, VPS4BMore
Sodium-tetradecyl-sulfatehsa04261Adrenergic signaling in cardiomyocytes1.26E-026P67936, P51828, Q99941, P18848, Q13362, P23634TPM4, ADCY7, CREBL1, ATF4, PPP2R5C, ATP2B4More
Sodium-tetradecyl-sulfatehsa04340Hedgehog signaling pathway4.63E-023P22694, Q13635, P10415PRKACB, PTCH1, BCL2More
Sodium-tetradecyl-sulfatehsa04612Antigen processing and presentation5.66E-037P13765, P48382, P26715, P26717, Q13241, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Sodium-tetradecyl-sulfatehsa04613Neutrophil extracellular trap formation1.72E-0210O60603, P05164, P08246, Q9UM07, Q6FI13, Q15080, P20160, P08311, P21730, P21462TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF4, AZU1, CTSG, C5AR1, FPR1More
Sodium-tetradecyl-sulfatehsa04621NOD-like receptor signaling pathway2.39E-025P01584, P07900, P23458, Q9H3M7, P43490IL1B, HSP90AA1, JAK1, TXNIP, PBEF1More
Sodium-tetradecyl-sulfatehsa04640Hematopoietic cell lineage4.63E-026P14778, P27930, P11215, P07766, P01730, P09564IL1R1, IL1R2, ITGAM, CD3E, CD4, CD7More
Sodium-tetradecyl-sulfatehsa04650Natural killer cell mediated cytotoxicity1.98E-0310P19174, P01375, P06239, O60880, P20963, P42338, Q13241, P26718, P26717, P26715PLCG1, TNF, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, KLRC2, KLRC1More
Sodium-tetradecyl-sulfatehsa04658Th1 and Th2 cell differentiation2.21E-048P07766, P20963, P19174, P01730, P06239, Q9UL17, P14784, Q13761CD3E, CD247, PLCG1, CD4, LCK, TBX21, IL2RB, RUNX3More
Sodium-tetradecyl-sulfatehsa04659Th17 cell differentiation1.25E-038P19174, P01730, P06239, P14784, P14778, Q9UL17, P07766, P20963PLCG1, CD4, LCK, IL2RB, IL1R1, TBX21, CD3E, CD247More
Sodium-tetradecyl-sulfatehsa04660T cell receptor signaling pathway4.63E-026P42338, P19174, P07766, P20963, P01730, P06239PIK3CB, PLCG1, CD3E, CD247, CD4, LCKMore
Sodium-tetradecyl-sulfatehsa04662B cell receptor signaling pathway1.07E-025P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Sodium-tetradecyl-sulfatehsa04664Fc epsilon RI signaling pathway1.29E-024P42338, P07948, P19174, P09917PIK3CB, LYN, PLCG1, ALOX5More
Sodium-tetradecyl-sulfatehsa04724Glutamatergic synapse2.81E-024P43003, P63218, P50151, P15104SLC1A3, GNG5, GNG10, GLULMore
Sodium-tetradecyl-sulfatehsa04725Cholinergic synapse3.86E-024P22694, Q14643, P18848, P10415PRKACB, ITPR1, ATF4, BCL2More
Sodium-tetradecyl-sulfatehsa04750Inflammatory mediator regulation of TRP channels3.85E-024P14778, P19174, P42338, P24723IL1R1, PLCG1, PIK3CB, PRKCHMore
Sodium-tetradecyl-sulfatehsa04911Insulin secretion4.85E-023P51828, Q99941, P18848ADCY7, CREBL1, ATF4More
Sodium-tetradecyl-sulfatehsa04915Estrogen signaling pathway1.20E-0310P14780, P22694, Q99941, P18848, P51828, P07900, P11142, Q14643, Q15788, P10415MMP9, PRKACB, CREBL1, ATF4, ADCY7, HSP90AA1, HSPA8, ITPR1, NCOA1, BCL2More
Sodium-tetradecyl-sulfatehsa04918Thyroid hormone synthesis2.05E-036P22694, P51828, Q99941, P18848, Q14643, P05543PRKACB, ADCY7, CREBL1, ATF4, ITPR1, SERPINA7More
Sodium-tetradecyl-sulfatehsa04925Aldosterone synthesis and secretion2.50E-024Q99941, P18848, P51828, P23634CREBL1, ATF4, ADCY7, ATP2B4More
Sodium-tetradecyl-sulfatehsa04927Cortisol synthesis and secretion7.21E-045Q14643, Q99941, P18848, P51828, P22694ITPR1, CREBL1, ATF4, ADCY7, PRKACBMore
Sodium-tetradecyl-sulfatehsa04928Parathyroid hormone synthesis, secretion and action1.60E-025Q14643, P22694, P23771, P18848, P10415ITPR1, PRKACB, GATA3, ATF4, BCL2More
Sodium-tetradecyl-sulfatehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Sodium-tetradecyl-sulfatehsa05120Epithelial cell signaling in Helicobacter pylori infection2.78E-035P09341, P19875, P19174, P25024, P07948CXCL1, CXCL2, PLCG1, CXCR1, LYNMore
Sodium-tetradecyl-sulfatehsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Sodium-tetradecyl-sulfatehsa05144Malaria1.80E-024O60603, P01375, P35443, P26718TLR2, TNF, THBS4, KLRK1More
Sodium-tetradecyl-sulfatehsa05146Amoebiasis2.13E-0613Q13751, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P22694, P12814, P08311LAMB3, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSGMore
Sodium-tetradecyl-sulfatehsa05152Tuberculosis4.71E-026P48382, O60603, P01375, P10415, P13765, Q9UDY8RFX5, TLR2, TNF, BCL2, HLA-DOB, MALT1More
Sodium-tetradecyl-sulfatehsa05163Human cytomegalovirus infection3.61E-0313P42338, P63218, P50151, P51828, P23458, P01106, P14778, P01584, P61073, Q13651, Q99941, P18848, P30101PIK3CB, GNG5, GNG10, ADCY7, JAK1, MYC, IL1R1, IL1B, CXCR4, IL10RA, CREBL1, ATF4, PDIA3More
Sodium-tetradecyl-sulfatehsa05167Kaposi sarcoma-associated herpesvirus infection7.60E-038P42338, P63218, P50151, P09341, P19875, P19174, P07948, P01106PIK3CB, GNG5, GNG10, CXCL1, CXCL2, PLCG1, LYN, MYCMore
Sodium-tetradecyl-sulfatehsa05169Epstein-Barr virus infection1.27E-029P01106, Q13547, P42338, P07948, P30101, Q13761, O75293, P07766, P20963MYC, HDAC1, PIK3CB, LYN, PDIA3, RUNX3, GADD45B, CD3E, CD247More
Sodium-tetradecyl-sulfatehsa05170Human immunodeficiency virus 1 infection3.15E-028P42338, P63218, P50151, P30101, P01730, P19174, P07766, P20963PIK3CB, GNG5, GNG10, PDIA3, CD4, PLCG1, CD3E, CD247More
Sodium-tetradecyl-sulfatehsa05202Transcriptional misregulation in cancer2.87E-0210Q15532, P14780, P27930, Q15744, Q16548, O15550, P05164, P08246, Q9C0K0, P24522SS18, MMP9, IL1R2, CEBPE, BCL2A1, UTX, MPO, ELA2, BCL11B, GADD45AMore
Sodium-tetradecyl-sulfatehsa05203Viral carcinogenesis1.26E-026Q99941, P18848, P23458, P27348, Q7KZF4, P61978CREBL1, ATF4, JAK1, YWHAQ, SND1, HNRPKMore
Sodium-tetradecyl-sulfatehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer8.27E-036P42338, P19174, P07766, P20963, P06239, P01730PIK3CB, PLCG1, CD3E, CD247, LCK, CD4More
Sodium-tetradecyl-sulfatehsa05310Asthma7.04E-033P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Sodium-tetradecyl-sulfatehsa05321Inflammatory bowel disease2.38E-035O60603, P01375, P13765, Q14765, P23771TLR2, TNF, HLA-DOB, STAT4, GATA3More
Sodium-tetradecyl-sulfatehsa05323Rheumatoid arthritis2.72E-024P01375, P13765, P09341, O60603TNF, HLA-DOB, CXCL1, TLR2More
Sodium-tetradecyl-sulfatehsa05332Graft-versus-host disease6.12E-034P13765, P01375, P26715, Q13241HLA-DOB, TNF, KLRC1, KLRD1More

Community members of Sodium-tetradecyl-sulfate (SDC: 0.12)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)