PharmaCoNets of Sapropterin (SPCN: 0.96 )

Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Sapropterinhsa03010Ribosome1.03E-022P46777, P50914RPL5, RPL14More
Sapropterinhsa04142Lysosome3.31E-023P43234, Q9UBR2, P34059CTSO, CTSZ, GALNSMore
Sapropterinhsa04630JAK-STAT signaling pathway1.44E-024P01106, Q09472, P48551, P16871MYC, EP300, IFNAR2, IL7RMore
Sapropterinhsa04640Hematopoietic cell lineage1.67E-024P20023, P11836, P09693, P16871CR2, MS4A1, CD3G, IL7RMore
Sapropterinhsa04919Thyroid hormone signaling pathway4.44E-023P60709, Q09472, P01106ACTB, EP300, MYCMore
Sapropterinhsa05164Influenza A8.62E-034Q09472, P48551, P29728, P60709EP300, IFNAR2, OAS2, ACTBMore
Sapropterinhsa05169Epstein-Barr virus infection1.42E-025P20023, P01106, P48551, P29728, P09693CR2, MYC, IFNAR2, OAS2, CD3GMore
Sapropterinhsa05171Coronavirus disease - COVID-191.93E-024P48551, P29728, P46777, P50914IFNAR2, OAS2, RPL5, RPL14More
Sapropterinhsa05211Renal cell carcinoma1.67E-022Q09472, Q99814EP300, EPAS1More

Community members of Sapropterin (SDC: 0.69)

UniProtACGene NameProtein NameReported/
Predicted
DisGeNETSPVSdrugabilitySHiSBiNSDisG
P07101THTyrosine 3NonemonooxygenaseReported00.04320.08880.49370.6929
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)