PharmaCoNets

PharmaCoNets of Riboflavin (S_PCN: 1.45 )

Riboflavin regulated-network (S_DN: 2.54)

Drug Name

Pathway ID

Pathway name

P-value

No. of gene members

UniProt AC

Gene name

Detail of Coexpression

Riboflavin

hsa00440

Phosphonate and phosphinate metabolism

4.98E-02

Q9Y6K0

CEPT1

Riboflavin

hsa00670

One carbon pool by folate

9.25E-03

O95954, Q99707

FTCD, MTR

Riboflavin

hsa00740

Riboflavin metabolism

4.98E-02

Q969G6

RFK

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P24387	CRHBP	Corticotropin-releasing factor-binding protein	Q969G6	RFK	Riboflavin kinase	-0.761
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q96G91	P2RY11	P2Y purinoceptor 11	Q969G6	RFK	Riboflavin kinase	0.722
Q96G91	P2RY11	P2Y purinoceptor 11	Q969G6	RFK	Riboflavin kinase	0.722
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q969G6	RFK	Riboflavin kinase	Q969G6	RFK	Riboflavin kinase	1
P24387	CRHBP	Corticotropin-releasing factor-binding protein	Q969G6	RFK	Riboflavin kinase	-0.761
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P40818	USP8	Ubiquitin carboxyl-terminal hydrolase 8	P30043	BLVRB	Flavin reductase	-0.711
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q93086	P2RX5	P2X purinoceptor 5	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.713
Q93086	P2RX5	P2X purinoceptor 5	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.713
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P05107	ITGB2	Integrin beta-2	Q969G6	RFK	Riboflavin kinase	0.758
Q969G6	RFK	Riboflavin kinase	Q969G6	RFK	Riboflavin kinase	1
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P40818	USP8	Ubiquitin carboxyl-terminal hydrolase 8	P30043	BLVRB	Flavin reductase	-0.711
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P24387	CRHBP	Corticotropin-releasing factor-binding protein	Q969G6	RFK	Riboflavin kinase	-0.761
P40818	USP8	Ubiquitin carboxyl-terminal hydrolase 8	P30043	BLVRB	Flavin reductase	-0.711
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P05107	ITGB2	Integrin beta-2	Q969G6	RFK	Riboflavin kinase	0.758
P24387	CRHBP	Corticotropin-releasing factor-binding protein	Q969G6	RFK	Riboflavin kinase	-0.761
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P40818	USP8	Ubiquitin carboxyl-terminal hydrolase 8	P30043	BLVRB	Flavin reductase	-0.711
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P48651	PTDSS1	Phosphatidylserine synthase 1	Q969G6	RFK	Riboflavin kinase	0.871
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q96G91	P2RY11	P2Y purinoceptor 11	Q969G6	RFK	Riboflavin kinase	0.722
Q93086	P2RX5	P2X purinoceptor 5	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.713
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q969G6	RFK	Riboflavin kinase	Q969G6	RFK	Riboflavin kinase	1
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P05107	ITGB2	Integrin beta-2	Q969G6	RFK	Riboflavin kinase	0.758
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q93086	P2RX5	P2X purinoceptor 5	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.713
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q96G91	P2RY11	P2Y purinoceptor 11	Q969G6	RFK	Riboflavin kinase	0.722
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
P49759	CLK1	Dual specificity protein kinase CLK1	P30043	BLVRB	Flavin reductase	-0.764
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702
Q13822	ENPP2	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	0.702