PharmaCoNets of Rasagiline (SPCN: 10.38 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Rasagilinehsa00190Oxidative phosphorylation3.56E-023Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Rasagilinehsa00230Purine metabolism1.81E-022P20839, Q02153IMPDH1, GUCY1B3More
Rasagilinehsa00260Glycine, serine and threonine metabolism1.99E-021P22557ALAS2More
Rasagilinehsa00565Ether lipid metabolism3.94E-021Q8N661TMEM86BMore
Rasagilinehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Rasagilinehsa03013RNA transport3.98E-029P52298, Q09161, O14893, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, NCBP1, GEMIN2, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Rasagilinehsa04120Ubiquitin mediated proteolysis2.51E-036Q14145, Q13042, P62837, Q15751, O95071, P0CG47KEAP1, CDC16, UBE2D2, HERC1, UBR5, UBBMore
Rasagilinehsa04137Mitophagy - animal9.52E-032Q07817, P0CG47BCL2L1, UBBMore
Rasagilinehsa04145Phagosome1.66E-039Q15080, P14598, Q13509, P68371, Q13488, P05164, O60603, P35443, P13765NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, HLA-DOBMore
Rasagilinehsa04217Necroptosis2.34E-024P01375, P48023, Q14765, Q99878TNF, FASLG, STAT4, H2AC14More
Rasagilinehsa04666Fc gamma R-mediated phagocytosis2.42E-025P23528, P06396, O14494, P14598, P17252CFL1, GSN, PLPP1, NCF1, PRKCAMore
Rasagilinehsa04672Intestinal immune network for IgA production1.62E-023P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Rasagilinehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Rasagilinehsa04744Phototransduction2.80E-022P62873, P0DP23GNB1, CALM1More
Rasagilinehsa04916Melanogenesis4.80E-024P0DP23, Q9UJU2, P17252, P04628CALM1, LEF1, PRKCA, WNT1More
Rasagilinehsa04932Non-alcoholic fatty liver disease2.74E-023P01375, P49841, P48023TNF, GSK3B, FASLGMore
Rasagilinehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Rasagilinehsa05132Salmonella infection2.93E-0210P51617, Q9UJU2, Q13489, P10415, O75369, O60603, Q9BQS8, Q13561, Q13509, P68371IRAK1, LEF1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DCTN2, TUBB3, TUBB2CMore
Rasagilinehsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Rasagilinehsa05152Tuberculosis5.68E-039Q13488, P0DP23, P48382, O60603, P10415, P13765, P01568, Q9UDY8, P51617TCIRG1, CALM1, RFX5, TLR2, BCL2, HLA-DOB, IFNA21, MALT1, IRAK1More
Rasagilinehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Rasagilinehsa05170Human immunodeficiency virus 1 infection5.94E-0312P62873, P0DP23, P17252, O00463, Q14643, P01568, P51617, O60603, P23528, P10415, Q93034, Q9Y6Q5GNB1, CALM1, PRKCA, TRAF5, ITPR1, IFNA21, IRAK1, TLR2, CFL1, BCL2, CUL5, AP1M2More
Rasagilinehsa05202Transcriptional misregulation in cancer3.51E-0211Q12778, Q15532, P14780, P14923, Q16548, Q13489, Q13077, P35226, P05164, P08246, Q9C0K0FOXO1, SS18, MMP9, JUP, BCL2A1, BIRC3, TRAF1, BMI1, MPO, ELA2, BCL11BMore
Rasagilinehsa05205Proteoglycans in cancer1.09E-0210Q13009, Q12955, Q14643, O75369, P14780, P17252, O60603, P04628, Q13635, P08962TIAM1, ANK3, ITPR1, FLNB, MMP9, PRKCA, TLR2, WNT1, PTCH1, CD63More
Rasagilinehsa05320Autoimmune thyroid disease8.64E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Rasagilinehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Rasagilinehsa05332Graft-versus-host disease3.70E-022P48023, P01375FASLG, TNFMore

Community members of Rasagiline (SDC: 2.91)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P10415BCL2Apoptosis regulator BclNone2Reported10.03410.527112.0714
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
Q07817BCL2L1BclNone2Nonelike protein 1Predicted10.08720.434911.9134
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)