PharmaCoNets of Quinestrol (SPCN: 19.46 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Quinestrolhsa00030Pentose phosphate pathway1.69E-022P60891, P37837PRPS1, TALDO1More
Quinestrolhsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Quinestrolhsa00983Drug metabolism - other enzymes3.59E-023P04183, P32320, P05164TK1, CDA, MPOMore
Quinestrolhsa01230Biosynthesis of amino acids3.59E-023P60891, Q99707, P37837PRPS1, MTR, TALDO1More
Quinestrolhsa03008Ribosome biogenesis in eukaryotes6.93E-046Q9NYH9, O14980, O60832, P78345, Q9BVP2, Q9GZY0UTP6, XPO1, DKC1, RPP38, GNL3, NXF2; NXF2BMore
Quinestrolhsa03013RNA transport1.32E-0514O14980, P52298, O14893, P61326, Q9GZY0, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, P23588, Q9Y6A5, Q53GS7XPO1, NCBP2, GEMIN2, MAGOH, NXF2; NXF2B, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, EIF4B, TACC3, GLE1More
Quinestrolhsa03015mRNA surveillance pathway9.78E-036O43148, Q16537, P61326, Q9GZY0, P52298, Q53GS7RNMT, PPP2R5E, MAGOH, NXF2; NXF2B, NCBP2, GLE1More
Quinestrolhsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, P25025, P14784CXCL1, CXCL2, CXCR1, CXCR2, IL2RBMore
Quinestrolhsa04062Chemokine signaling pathway1.83E-028P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10More
Quinestrolhsa04064NF-kappa B signaling pathway2.15E-027P14778, P19174, Q04759, P06239, P09341, P19875, Q06643IL1R1, PLCG1, PRKCQ, LCK, CXCL1, CXCL2, LTBMore
Quinestrolhsa04071Sphingolipid signaling pathway3.08E-025P17252, Q16537, Q9BX95, P04637, P10415PRKCA, PPP2R5E, SGPP1, TP53, BCL2More
Quinestrolhsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Quinestrolhsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Quinestrolhsa04145Phagosome3.27E-049P63261, Q15080, P14598, Q13509, P68371, P05164, O60603, P35443, P13765ACTG1, NCF4, NCF1, TUBB3, TUBB2C, MPO, TLR2, THBS4, HLA-DOBMore
Quinestrolhsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Quinestrolhsa04540Gap junction3.53E-024P17252, Q13509, P68371, Q14643PRKCA, TUBB3, TUBB2C, ITPR1More
Quinestrolhsa04613Neutrophil extracellular trap formation2.89E-0210P17252, O60603, P05164, P08246, Q9UM07, Q6FI13, P14598, Q15080, P21462, P63261PRKCA, TLR2, MPO, ELA2, PADI4, H2AC18; H2AC19, NCF1, NCF4, FPR1, ACTG1More
Quinestrolhsa04640Hematopoietic cell lineage1.37E-027P14778, P27930, P11215, P25063, P07766, P01732, P09564IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD7More
Quinestrolhsa04650Natural killer cell mediated cytotoxicity2.48E-038P19174, P06239, O60880, P20963, P42338, Q13241, P26718, O14931PLCG1, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3More
Quinestrolhsa04658Th1 and Th2 cell differentiation2.21E-048Q04759, P07766, P20963, P19174, P06239, Q9UL17, P14784, Q13761PRKCQ, CD3E, CD247, PLCG1, LCK, TBX21, IL2RB, RUNX3More
Quinestrolhsa04659Th17 cell differentiation1.25E-038Q04759, P19174, P06239, P14784, P14778, Q9UL17, P07766, P20963PRKCQ, PLCG1, LCK, IL2RB, IL1R1, TBX21, CD3E, CD247More
Quinestrolhsa04660T cell receptor signaling pathway3.37E-038Q04759, P42338, P19174, P07766, P20963, P01732, Q13191, P06239PRKCQ, PIK3CB, PLCG1, CD3E, CD247, CD8A, CBLB, LCKMore
Quinestrolhsa04666Fc gamma R-mediated phagocytosis9.96E-035P23528, P49006, P06396, P14598, P17252CFL1, MARCKSL1, GSN, NCF1, PRKCAMore
Quinestrolhsa04750Inflammatory mediator regulation of TRP channels7.24E-035P14778, P19174, P42338, P24723, Q04759IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQMore
Quinestrolhsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Quinestrolhsa04972Pancreatic secretion1.99E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Quinestrolhsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Quinestrolhsa05120Epithelial cell signaling in Helicobacter pylori infection2.78E-035P09341, P19875, P19174, P25024, P25025CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Quinestrolhsa05132Salmonella infection2.10E-029Q9UJU2, P63261, Q13489, P10415, O60603, Q9BQS8, Q13561, Q13509, P68371LEF1, ACTG1, BIRC3, BCL2, TLR2, FYCO1, DCTN2, TUBB3, TUBB2CMore
Quinestrolhsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Quinestrolhsa05140Leishmaniasis4.13E-025P14598, P13765, O60603, P49006, Q15080NCF1, HLA-DOB, TLR2, MARCKSL1, NCF4More
Quinestrolhsa05146Amoebiasis2.21E-048P09341, P19875, P14778, P27930, P42338, P11215, P05089, P12814CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, ACTN1More
Quinestrolhsa05202Transcriptional misregulation in cancer6.80E-0312Q12778, Q15532, P41732, P14780, P14923, Q13489, O15550, P04637, P05164, P08246, Q9C0K0, P24522FOXO1, SS18, TSPAN7, MMP9, JUP, BIRC3, UTX, TP53, MPO, ELA2, BCL11B, GADD45AMore
Quinestrolhsa05205Proteoglycans in cancer2.66E-028Q14643, P63261, P04637, P14780, P17252, O60603, Q13635, P08962ITPR1, ACTG1, TP53, MMP9, PRKCA, TLR2, PTCH1, CD63More
Quinestrolhsa05216Thyroid cancer3.59E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Quinestrolhsa05217Basal cell carcinoma1.46E-024Q13635, Q9UJU2, P04637, P24522PTCH1, LEF1, TP53, GADD45AMore
Quinestrolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer8.27E-036P42338, P19174, P07766, P20963, P06239, Q04759PIK3CB, PLCG1, CD3E, CD247, LCK, PRKCQMore
Quinestrolhsa05323Rheumatoid arthritis3.53E-024P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Quinestrolhsa05418Fluid shear stress and atherosclerosis4.26E-026P14598, P14780, P63261, P04637, P10415, Q92974NCF1, MMP9, ACTG1, TP53, BCL2, ARHGEF2More

Community members of Quinestrol (SDC: 3.24)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
Q13093PLA2G7PlateletNoneactivating factor acetylhydrolasePredicted00.05050.20960.15580.6001
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)