PharmaCoNets of Pyridoxal-phosphate (SPCN: 2.88 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Pyridoxal-phosphatehsa00260Glycine, serine and threonine metabolism8.29E-031P22557ALAS2More
Pyridoxal-phosphatehsa00410beta-Alanine metabolism4.50E-021Q6ZQY3GADL1More
Pyridoxal-phosphatehsa00471D-Glutamine and D-glutamate metabolism2.28E-021Q7Z3D6C14orf159More
Pyridoxal-phosphatehsa00500Starch and sucrose metabolism3.88E-023O43451, P46976, P06737MGAM, GYG1, PYGLMore
Pyridoxal-phosphatehsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis4.50E-021Q14442PIGHMore
Pyridoxal-phosphatehsa00565Ether lipid metabolism4.50E-021Q8N661TMEM86BMore
Pyridoxal-phosphatehsa00730Thiamine metabolism3.79E-022P05186, P24666ALPL, ACP1More
Pyridoxal-phosphatehsa00770Pantothenate and CoA biosynthesis2.28E-021Q6ZQY3GADL1More
Pyridoxal-phosphatehsa00860Porphyrin and chlorophyll metabolism3.28E-021P22557ALAS2More
Pyridoxal-phosphatehsa04062Chemokine signaling pathway1.81E-023P10145, P09769, Q13009IL8, FGR, TIAM1More
Pyridoxal-phosphatehsa04064NF-kappa B signaling pathway2.29E-0311Q07817, P10415, O00463, P01375, Q04759, Q13077, P19784, Q16548, Q8WV28, P24522, P09341BCL2L1, BCL2, TRAF5, TNF, PRKCQ, TRAF1, CSNK2A2, BCL2A1, BLNK, GADD45A, CXCL1More
Pyridoxal-phosphatehsa04071Sphingolipid signaling pathway2.06E-027Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Pyridoxal-phosphatehsa04080Neuroactive ligand-receptor interaction2.54E-027P08311, Q15722, Q9H228, P21462, P21730, Q16581, P35318CTSG, LTB4R, EDG8, FPR1, C5AR1, C3AR1, ADMMore
Pyridoxal-phosphatehsa04115p53 signaling pathway4.09E-021Q07817BCL2L1More
Pyridoxal-phosphatehsa04137Mitophagy - animal1.51E-032P19784, Q07817CSNK2A2, BCL2L1More
Pyridoxal-phosphatehsa04215Apoptosis - multiple species2.47E-021Q07817BCL2L1More
Pyridoxal-phosphatehsa04340Hedgehog signaling pathway1.43E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Pyridoxal-phosphatehsa04520Adherens junction4.09E-021P19784CSNK2A2More
Pyridoxal-phosphatehsa04613Neutrophil extracellular trap formation1.37E-0212O60603, P05164, P08246, Q9UM07, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Pyridoxal-phosphatehsa04621NOD-like receptor signaling pathway2.64E-0210Q16539, Q14643, P10599, Q9H1Y0, P43490, O00463, P10415, P01375, P09341, P12838MAPK14, ITPR1, TXN, ATG5, PBEF1, TRAF5, BCL2, TNF, CXCL1, DEFA4More
Pyridoxal-phosphatehsa04657IL-17 signaling pathway1.28E-027O00463, Q16539, P49841, P09341, P14780, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNFMore
Pyridoxal-phosphatehsa04658Th1 and Th2 cell differentiation3.21E-039Q04759, P20963, P09693, Q16539, Q14765, P42226, P23771, Q9UL17, P13765PRKCQ, CD247, CD3G, MAPK14, STAT4, STAT6, GATA3, TBX21, HLA-DOBMore
Pyridoxal-phosphatehsa04659Th17 cell differentiation3.18E-028Q04759, Q16539, P42226, P13765, Q9UL17, P23771, P09693, P20963PRKCQ, MAPK14, STAT6, HLA-DOB, TBX21, GATA3, CD3G, CD247More
Pyridoxal-phosphatehsa04660T cell receptor signaling pathway1.07E-029P01375, Q04759, O95267, Q08881, P20963, P09693, P01732, Q16539, P49841TNF, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, MAPK14, GSK3BMore
Pyridoxal-phosphatehsa05022Pathways of neurodegeneration - multiple diseases4.91E-022P19784, Q07817CSNK2A2, BCL2L1More
Pyridoxal-phosphatehsa05120Epithelial cell signaling in Helicobacter pylori infection6.89E-032Q99437, P10145ATP6V0B, IL8More
Pyridoxal-phosphatehsa05150Staphylococcus aureus infection4.37E-026P21730, P21462, O75015, P13765, Q16581, P12838C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, DEFA4More
Pyridoxal-phosphatehsa05162Measles5.54E-032P19784, Q07817CSNK2A2, BCL2L1More
Pyridoxal-phosphatehsa05169Epstein-Barr virus infection4.32E-0211P13765, O00463, P16070, P10415, Q16539, P24522, Q8WV28, P01375, O60603, P09693, P20963HLA-DOB, TRAF5, CD44, BCL2, MAPK14, GADD45A, BLNK, TNF, TLR2, CD3G, CD247More
Pyridoxal-phosphatehsa05202Transcriptional misregulation in cancer8.07E-0414Q15532, P14780, P27930, Q16548, Q13077, Q15652, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, P24522SS18, MMP9, IL1R2, BCL2A1, TRAF1, JMJD1C, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, GADD45AMore
Pyridoxal-phosphatehsa05217Basal cell carcinoma1.43E-024Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Pyridoxal-phosphatehsa05220Chronic myeloid leukemia4.89E-021Q07817BCL2L1More
Pyridoxal-phosphatehsa05321Inflammatory bowel disease7.62E-047O60603, P01375, P13765, Q14765, Q9UL17, P42226, P23771TLR2, TNF, HLA-DOB, STAT4, TBX21, STAT6, GATA3More
Pyridoxal-phosphatehsa05323Rheumatoid arthritis4.28E-022Q99437, P10145ATP6V0B, IL8More

Community members of Pyridoxal-phosphate (SDC: 0.72)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)