| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Proparacaine | hsa00061 | Fatty acid biosynthesis | 4.07E-02 | 1 | P33121 | ACSL1 | More | | | Proparacaine | hsa00190 | Oxidative phosphorylation | 1.48E-02 | 2 | Q16718, O14521 | NDUFA5, SDHD | More | | | Proparacaine | hsa00590 | Arachidonic acid metabolism | 3.85E-02 | 2 | P11712, P09960 | CYP2C9, LTA4H | More | | | Proparacaine | hsa00591 | Linoleic acid metabolism | 4.07E-02 | 1 | P11712 | CYP2C9 | More | | | Proparacaine | hsa01100 | Metabolic pathways | 1.25E-02 | 11 | O14521, Q13370, P11712, P24666, P23743, O60701, P33121, Q9NY28, P09960, Q9Y2B2, Q16718 | SDHD, PDE3B, CYP2C9, ACP1, DGKA, UGDH, ACSL1, GALNT8, LTA4H, PIGL, NDUFA5 | More | | | Proparacaine | hsa03022 | Basal transcription factors | 2.17E-02 | 2 | O00268, Q15544 | TAF4, TAF11 | More | | | Proparacaine | hsa04020 | Calcium signaling pathway | 4.93E-02 | 3 | P17252, P25116, P20020 | PRKCA, F2R, ATP2B1 | More | | | Proparacaine | hsa04024 | cAMP signaling pathway | 4.93E-02 | 3 | P20020, Q13370, P25116 | ATP2B1, PDE3B, F2R | More | | | Proparacaine | hsa04072 | Phospholipase D signaling pathway | 3.29E-02 | 3 | P25116, P17252, P23743 | F2R, PRKCA, DGKA | More | | | Proparacaine | hsa04261 | Adrenergic signaling in cardiomyocytes | 3.29E-02 | 3 | P09493, P17252, P20020 | TPM1, PRKCA, ATP2B1 | More | | | Proparacaine | hsa04714 | Thermogenesis | 1.99E-02 | 3 | P33121, Q16718, O14521 | ACSL1, NDUFA5, SDHD | More | | | Proparacaine | hsa04726 | Serotonergic synapse | 1.64E-02 | 3 | P17252, P31645, P11712 | PRKCA, SLC6A4, CYP2C9 | More | | | Proparacaine | hsa04961 | Endocrine and other factor-regulated calcium reabsorption | 1.48E-02 | 2 | P20020, P17252 | ATP2B1, PRKCA | More | | | Proparacaine | hsa04970 | Salivary secretion | 4.83E-02 | 2 | P20020, P17252 | ATP2B1, PRKCA | More | | | Proparacaine | hsa04972 | Pancreatic secretion | 1.48E-02 | 2 | P20020, P17252 | ATP2B1, PRKCA | More | | | Proparacaine | hsa05016 | Huntington disease | 2.93E-02 | 4 | Q16718, O14521, O00268, Q13561 | NDUFA5, SDHD, TAF4, DCTN2 | More | | | Proparacaine | hsa05022 | Pathways of neurodegeneration - multiple diseases | 1.91E-02 | 5 | Q16718, O14521, Q13561, P17252, Q08752 | NDUFA5, SDHD, DCTN2, PRKCA, PPID | More | | | Proparacaine | hsa05415 | Diabetic cardiomyopathy | 3.80E-02 | 3 | P17252, Q16718, O14521 | PRKCA, NDUFA5, SDHD | More | |
|
