PharmaCoNets of Promazine (SPCN: 54.07 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Chlorpromazinehsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Chlorpromazinehsa00040Pentose and glucuronate interconversions4.00E-021P15121AKR1B1More
Chlorpromazinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Chlorpromazinehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Chlorpromazinehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Chlorpromazinehsa00230Purine metabolism4.60E-024Q13370, P36959, Q13956, P27707PDE3B, GMPR, PDE6H, DCKMore
Chlorpromazinehsa00240Pyrimidine metabolism4.50E-022P32320, P27707CDA, DCKMore
Chlorpromazinehsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Chlorpromazinehsa00534Glycosaminoglycan biosynthesis - heparan sulfate / heparin4.77E-021Q7LGA3HS2ST1More
Chlorpromazinehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Chlorpromazinehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Chlorpromazinehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Chlorpromazinehsa00600Sphingolipid metabolism3.76E-021P15289ARSAMore
Chlorpromazinehsa00620Pyruvate metabolism3.90E-022P07195, P11766LDHB, ADH5More
Chlorpromazinehsa00670One carbon pool by folate3.99E-022O95954, Q99707FTCD, MTRMore
Chlorpromazinehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Chlorpromazinehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Chlorpromazinehsa00790Folate biosynthesis2.02E-021P15121AKR1B1More
Chlorpromazinehsa00920Sulfur metabolism3.01E-021O95571ETHE1More
Chlorpromazinehsa00980Metabolism of xenobiotics by cytochrome P4506.38E-043P78417, P09211, P11712GSTO1, GSTP1, CYP2C9More
Chlorpromazinehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Chlorpromazinehsa00983Drug metabolism - other enzymes1.70E-043P04183, P32320, P05164TK1, CDA, MPOMore
Chlorpromazinehsa01100Metabolic pathways3.95E-0223Q9Y234, Q99707, P29218, P11310, P27707, Q13370, P36959, Q13956, P30043, Q02252, O60701, O14772, O95954, Q02318, P04406, O15466, P09960, Q9P2R7, Q9UHY7, P35573, Q13488, Q16718, Q02809LIPT1, MTR, IMPA1, ACADM, DCK, PDE3B, GMPR, PDE6H, BLVRB, ALDH6A1, UGDH, FPGT, FTCD, CYP27A1, GAPDH, ST8SIA5, LTA4H, SUCLA2, ENOPH1, AGL, TCIRG1, NDUFA5, PLOD1More
Chlorpromazinehsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Chlorpromazinehsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Chlorpromazinehsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Chlorpromazinehsa01522Endocrine resistance3.74E-046P14780, P22694, P04049, Q9UM47, P10415, Q13323MMP9, PRKACB, RAF1, NOTCH3, BCL2, BIKMore
Chlorpromazinehsa01524Platinum drug resistance4.45E-024P10415, Q13489, P78417, P43246BCL2, BIRC3, GSTO1, MSH2More
Chlorpromazinehsa02010ABC transporters1.99E-044P45844, P08183, Q8IZY2, Q99758ABCG1, ABCB1, ABCA7, ABCA3More
Chlorpromazinehsa03010Ribosome1.08E-0411P62753, P25398, P32969, P40429, P62829, Q07020, P18077, P36578, P27635, P05386, P62249RPS6, RPS12, RPL9, RPL13A, RPL23, RPL18, RPL35A, RPL4, RPL10, RPLP1, RPS16More
Chlorpromazinehsa03013RNA transport1.12E-0211P62826, P52298, O14893, P61326, Q7Z3B4, P35658, P63279, Q14152, O75822, P78345, Q9Y6A5RAN, NCBP2, GEMIN2, MAGOH, NUP54, NUP214, UBE2I, EIF3A, EIF3J, RPP38, TACC3More
Chlorpromazinehsa03015mRNA surveillance pathway3.62E-023O43148, P61326, P52298RNMT, MAGOH, NCBP2More
Chlorpromazinehsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Chlorpromazinehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Chlorpromazinehsa03040Spliceosome1.11E-0718Q14562, O43143, O60508, P17844, O14776, P08579, O75940, P52298, P09651, Q15365, O75494, Q07955, Q01130, Q13243, P11142, O95777, O43447, P61326DHX8, DHX15, CDC40, DDX5, TCERG1, SNRPB2, SMNDC1, NCBP2, HNRNPA1, PCBP1, FUSIP1, SFRS1, SFRS2, SFRS5, HSPA8, LSM8, PPIH, MAGOHMore
Chlorpromazinehsa03050Proteasome5.53E-032P43686, P28070PSMC4, PSMB4More
Chlorpromazinehsa03060Protein export4.46E-032Q15070, O76094OXA1L, SRP72More
Chlorpromazinehsa03320PPAR signaling pathway2.89E-034Q6PCB7, O00767, Q9UNU6, Q02318SLC27A1, SCD, CYP8B1, CYP27A1More
Chlorpromazinehsa03430Mismatch repair4.38E-021P20585MSH3More
Chlorpromazinehsa03460Fanconi anemia pathway3.70E-033Q9NPI8, O60673, Q9UNA4FANCF, REV3L, POLIMore
Chlorpromazinehsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Chlorpromazinehsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Chlorpromazinehsa04014Ras signaling pathway1.42E-0310P04049, P31751, P20827, P49767, Q13009, P17252, Q15311, P0DP23, P62873, P19174RAF1, AKT2, EFNA1, VEGFC, TIAM1, PRKCA, RALBP1, CALM1, GNB1, PLCG1More
Chlorpromazinehsa04015Rap1 signaling pathway3.67E-0412P04049, P20827, P49767, P06213, Q13009, O00522, Q08828, P51828, P31751, P0DP23, P17252, P19174RAF1, EFNA1, VEGFC, INSR, TIAM1, KRIT1, ADCY1, ADCY7, AKT2, CALM1, PRKCA, PLCG1More
Chlorpromazinehsa04020Calcium signaling pathway1.04E-0611P27987, Q08828, Q13557, P17252, O15399, P19174, P61073, P0DP23, P51828, P23634, P49767ITPKB, ADCY1, CAMK2D, PRKCA, GRIN2D, PLCG1, CXCR4, CALM1, ADCY7, ATP2B4, VEGFCMore
Chlorpromazinehsa04022cGMP-PKG signaling pathway3.15E-021P04049RAF1More
Chlorpromazinehsa04024cAMP signaling pathway1.25E-0310Q08828, P51828, P31751, P0DP23, P23634, P04049, Q13557, Q13370, O15399, Q13009ADCY1, ADCY7, AKT2, CALM1, ATP2B4, RAF1, CAMK2D, PDE3B, GRIN2D, TIAM1More
Chlorpromazinehsa04062Chemokine signaling pathway9.36E-0311P51684, Q8NHW4, P19174, P62873, Q08828, P51828, Q13009, P14598, P42224, P31751, P04049CCR6, CCL4L2, PLCG1, GNB1, ADCY1, ADCY7, TIAM1, NCF1, STAT1, AKT2, RAF1More
Chlorpromazinehsa04064NF-kappa B signaling pathway2.28E-049P10415, Q13489, P51617, P01584, P29965, P19174, O75293, Q8NHW4, Q9NQC7BCL2, BIRC3, IRAK1, IL1B, CD40LG, PLCG1, GADD45B, CCL4L2, CYLDMore
Chlorpromazinehsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Chlorpromazinehsa04070Phosphatidylinositol signaling system5.66E-046P19174, P0DP23, P23743, P48426, P27987, P17252PLCG1, CALM1, DGKA, PIP4K2A, ITPKB, PRKCAMore
Chlorpromazinehsa04071Sphingolipid signaling pathway3.96E-0812P04049, P17252, P21453, Q9H228, P01375, Q13510, Q13362, Q9BX95, Q16539, P10415, Q9UQC2, P01042RAF1, PRKCA, S1PR1, EDG8, TNF, ASAH1, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2, KNG1More
Chlorpromazinehsa04072Phospholipase D signaling pathway9.87E-039P04049, P31751, P19174, P17252, Q15438, Q08828, P51828, P23743, P00734RAF1, AKT2, PLCG1, PRKCA, PSCD1, ADCY1, ADCY7, DGKA, F2More
Chlorpromazinehsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Chlorpromazinehsa04114Oocyte meiosis6.23E-035Q9Y6D9, P51812, Q02750, P16298, Q17RY0MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Chlorpromazinehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Chlorpromazinehsa04137Mitophagy - animal3.55E-044Q96CV9, Q9H1Y0, P18848, O43524OPTN, ATG5, ATF4, FOXO3More
Chlorpromazinehsa04140Autophagy - animal1.61E-028P31751, P04049, Q7L523, Q96RR4, O75460, P10415, Q96GC9, Q8TEV9AKT2, RAF1, RRAGA, CAMKK2, ERN1, BCL2, TMEM49, SMCR8More
Chlorpromazinehsa04141Protein processing in endoplasmic reticulum4.88E-024P18848, O60337, P11142, P07900ATF4, MARH6, HSPA8, HSP90AA1More
Chlorpromazinehsa04144Endocytosis8.99E-0312P11142, Q9H444, O43633, O75351, Q9NZZ3, Q15438, Q14161, P14784, Q96QK1, Q9UMY4, Q9Y5X3, Q9UNH7HSPA8, CHMP4B, CHMP2A, VPS4B, CHMP5, PSCD1, GIT2, IL2RB, VPS35, SNX12, SNX5, SNX6More
Chlorpromazinehsa04145Phagosome5.56E-038P60709, P63261, Q15075, Q15080, P14598, Q13509, Q13488, O60603ACTB, ACTG1, EEA1, NCF4, NCF1, TUBB3, TCIRG1, TLR2More
Chlorpromazinehsa04146Peroxisome3.03E-046O43933, O96011, P56589, Q9UKG9, O75521, P33121PEX1, PEX11B, PEX3, CROT, ECI2, ACSL1More
Chlorpromazinehsa04150mTOR signaling pathway2.32E-021P04049RAF1More
Chlorpromazinehsa04151PI3K-Akt signaling pathway4.68E-0318O43521, P27348, P20827, P49767, Q13362, P08238, P62873, P16144, P48551, P14784, P23458, P01568, P15336, P18848, P10415, P17252, Q16513, Q6ZUJ8BCL2L11, YWHAQ, EFNA1, VEGFC, PPP2R5C, HSP90AB1, GNB1, ITGB4, IFNAR2, IL2RB, JAK1, IFNA21, ATF2, ATF4, BCL2, PRKCA, PKN2, PIK3AP1More
Chlorpromazinehsa04210Apoptosis8.00E-058O76075, P07384, P01375, Q9NR28, Q16548, P60709, P63261, P04049DFFB, CAPN1, TNF, DIABLO, BCL2A1, ACTB, ACTG1, RAF1More
Chlorpromazinehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Chlorpromazinehsa04217Necroptosis1.49E-1122P01375, P01568, P23458, P48023, Q13489, Q9NQC7, P42224, Q14765, P07900, P08238, P15104, P05141, P01584, P0C0S5, Q6FI13, Q99878, P10415, Q13557, Q9H444, O43633, Q9NZZ3, O75351TNF, IFNA21, JAK1, FASLG, BIRC3, CYLD, STAT1, STAT4, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, H2AC14, BCL2, CAMK2D, CHMP4B, CHMP2A, CHMP5, VPS4BMore
Chlorpromazinehsa04218Cellular senescence2.49E-021P04049RAF1More
Chlorpromazinehsa04261Adrenergic signaling in cardiomyocytes4.46E-0713P09493, P07550, Q08828, P51828, P22694, P31751, P18848, Q13362, P0DP23, Q13557, P17252, P10415, P23634TPM1, ADRB2, ADCY1, ADCY7, PRKACB, AKT2, ATF4, PPP2R5C, CALM1, CAMK2D, PRKCA, BCL2, ATP2B4More
Chlorpromazinehsa04270Vascular smooth muscle contraction2.32E-021P04049RAF1More
Chlorpromazinehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Chlorpromazinehsa04360Axon guidance3.05E-049P61073, P16333, P20827, O95631, P17252, Q13557, P23528, P04049, P19174CXCR4, NCK1, EFNA1, NTN1, PRKCA, CAMK2D, CFL1, RAF1, PLCG1More
Chlorpromazinehsa04370VEGF signaling pathway2.77E-044P16298, Q05397, Q02750, P04049PPP3CB, PTK2, MAP2K1, RAF1More
Chlorpromazinehsa04371Apelin signaling pathway1.61E-028P62873, P31751, P04049, Q08828, P51828, Q13370, Q13485, P0DP23GNB1, AKT2, RAF1, ADCY1, ADCY7, PDE3B, SMAD4, CALM1More
Chlorpromazinehsa04380Osteoclast differentiation4.18E-027Q9NQC7, Q9UQC2, P23458, P42224, P01584, Q15080, P14598CYLD, GAB2, JAK1, STAT1, IL1B, NCF4, NCF1More
Chlorpromazinehsa04390Hippo signaling pathway2.80E-022P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa04510Focal adhesion1.26E-028P16144, O75369, Q15942, P17252, Q13489, P10415, P04049, P49767ITGB4, FLNB, ZYX, PRKCA, BIRC3, BCL2, RAF1, VEGFCMore
Chlorpromazinehsa04520Adherens junction1.58E-022P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa04530Tight junction6.83E-046P60709, P63261, P16989, P56750, Q14247, P60660ACTB, ACTG1, CSDA, CLDN17, CTTN, MYL6More
Chlorpromazinehsa04540Gap junction1.12E-026P17252, Q13509, P68371, Q08828, P51828, P04049PRKCA, TUBB3, TUBB2C, ADCY1, ADCY7, RAF1More
Chlorpromazinehsa04550Signaling pathways regulating pluripotency of stem cells9.61E-034Q13873, P04049, Q02750, Q86SE9BMPR2, RAF1, MAP2K1, PCGF5More
Chlorpromazinehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Chlorpromazinehsa04611Platelet activation2.61E-022P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Chlorpromazinehsa04613Neutrophil extracellular trap formation1.49E-1124P04049, P11215, O60603, P05164, P08246, Q9UM07, Q13547, P04908, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539RAF1, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Chlorpromazinehsa04620Toll-like receptor signaling pathway1.33E-025P51617, P01568, P31751, P42224, Q8NHW4IRAK1, IFNA21, AKT2, STAT1, CCL4L2More
Chlorpromazinehsa04621NOD-like receptor signaling pathway2.73E-0415P01584, P08238, P23458, P42224, P01568, Q9H3M7, Q13489, Q9H1Y0, P43490, O00463, P10415, Q05823, P01375, P49913, P12838IL1B, HSP90AB1, JAK1, STAT1, IFNA21, TXNIP, BIRC3, ATG5, PBEF1, TRAF5, BCL2, RNASEL, TNF, CAMP, DEFA4More
Chlorpromazinehsa04623Cytosolic DNA-sensing pathway4.25E-022P01568, Q8NHW4IFNA21, CCL4L2More
Chlorpromazinehsa04625C-type lectin receptor signaling pathway1.49E-021P04049RAF1More
Chlorpromazinehsa04630JAK-STAT signaling pathway1.77E-039P31751, P10415, P42224, P23458, P14784, P16871, Q13651, P04049, P01568AKT2, BCL2, STAT1, JAK1, IL2RB, IL7R, IL10RA, RAF1, IFNA21More
Chlorpromazinehsa04640Hematopoietic cell lineage2.82E-034P08514, P21926, P07766, P09564ITGA2B, CD9, CD3E, CD7More
Chlorpromazinehsa04650Natural killer cell mediated cytotoxicity5.84E-0611P16298, P50591, P01375, P20963, Q02750, P04049, Q13241, P26718, P26717, Q14953, P26715PPP3CB, TNFSF10, TNF, CD247, MAP2K1, RAF1, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Chlorpromazinehsa04657IL-17 signaling pathway5.66E-0510P07900, O00463, Q16539, P49841, P19875, P14780, Q9UJX4, P80188, P01375, P01584HSP90AA1, TRAF5, MAPK14, GSK3B, CXCL2, MMP9, ANAPC5, LCN2, TNF, IL1BMore
Chlorpromazinehsa04660T cell receptor signaling pathway1.66E-021P04049RAF1More
Chlorpromazinehsa04662B cell receptor signaling pathway2.13E-033P25963, P20023, P04049NFKBIA, CR2, RAF1More
Chlorpromazinehsa04664Fc epsilon RI signaling pathway1.16E-021P04049RAF1More
Chlorpromazinehsa04666Fc gamma R-mediated phagocytosis1.47E-027P08575, P19174, P04049, P23528, Q9UQC2, P14598, P17252PTPRC, PLCG1, RAF1, CFL1, GAB2, NCF1, PRKCAMore
Chlorpromazinehsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Chlorpromazinehsa04670Leukocyte transendothelial migration4.07E-022P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa04713Circadian entrainment5.61E-057O15399, P0DP23, Q13557, P17252, P62873, Q08828, P51828GRIN2D, CALM1, CAMK2D, PRKCA, GNB1, ADCY1, ADCY7More
Chlorpromazinehsa04714Thermogenesis3.66E-058Q16539, P15336, P60709, P63261, P33121, Q16718, O14521, P36542MAPK14, ATF2, ACTB, ACTG1, ACSL1, NDUFA5, SDHD, ATP5C1More
Chlorpromazinehsa04720Long-term potentiation1.22E-0410P17252, Q13557, P16298, P0DP23, P51812, P18848, O15399, Q08828, Q02750, P04049PRKCA, CAMK2D, PPP3CB, CALM1, RPS6KA3, ATF4, GRIN2D, ADCY1, MAP2K1, RAF1More
Chlorpromazinehsa04722Neurotrophin signaling pathway7.10E-034P04049, P49841, O43524, P48023RAF1, GSK3B, FOXO3, FASLGMore
Chlorpromazinehsa04724Glutamatergic synapse5.91E-037P48058, O15399, Q08828, P51828, P17252, P62873, P15104GRIA4, GRIN2D, ADCY1, ADCY7, PRKCA, GNB1, GLULMore
Chlorpromazinehsa04725Cholinergic synapse4.42E-048Q08828, P51828, P17252, P62873, P18848, Q13557, P31751, P10415ADCY1, ADCY7, PRKCA, GNB1, ATF4, CAMK2D, AKT2, BCL2More
Chlorpromazinehsa04726Serotonergic synapse1.33E-021P04049RAF1More
Chlorpromazinehsa04727GABAergic synapse4.08E-025Q08828, P51828, P62873, P46459, P17252ADCY1, ADCY7, GNB1, NSF, PRKCAMore
Chlorpromazinehsa04730Long-term depression1.16E-021P04049RAF1More
Chlorpromazinehsa04740Olfactory transduction5.88E-034P62873, Q9H255, Q13557, P0DP23GNB1, OR51E2, CAMK2D, CALM1More
Chlorpromazinehsa04742Taste transduction1.01E-021P30939HTR1FMore
Chlorpromazinehsa04744Phototransduction1.30E-052P62873, P0DP23GNB1, CALM1More
Chlorpromazinehsa04750Inflammatory mediator regulation of TRP channels4.32E-058P01584, Q08828, P51828, Q13557, P19174, P17252, P0DP23, P01042IL1B, ADCY1, ADCY7, CAMK2D, PLCG1, PRKCA, CALM1, KNG1More
Chlorpromazinehsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Chlorpromazinehsa04910Insulin signaling pathway2.51E-034P22694, P06737, P04049, P49841PRKACB, PYGL, RAF1, GSK3BMore
Chlorpromazinehsa04911Insulin secretion3.47E-024Q08828, P17252, P18848, Q13557ADCY1, PRKCA, ATF4, CAMK2DMore
Chlorpromazinehsa04912GnRH signaling pathway1.35E-026P17252, Q08828, P18848, Q13557, P0DP23, P04049PRKCA, ADCY1, ATF4, CAMK2D, CALM1, RAF1More
Chlorpromazinehsa04913Ovarian steroidogenesis2.45E-033P42330, P22694, P06213AKR1C3, PRKACB, INSRMore
Chlorpromazinehsa04914Progesterone-mediated oocyte maturation6.70E-0411Q17RY0, Q08828, P51828, P31751, Q13370, Q9UJX4, Q9Y6D9, P08238, P51812, Q02750, P04049CPEB4, ADCY1, ADCY7, AKT2, PDE3B, ANAPC5, MAD1L1, HSP90AB1, RPS6KA3, MAP2K1, RAF1More
Chlorpromazinehsa04915Estrogen signaling pathway2.35E-0310P04049, P18848, Q08828, P51828, P31751, P08238, P11142, P0DP23, Q15788, P10415RAF1, ATF4, ADCY1, ADCY7, AKT2, HSP90AB1, HSPA8, CALM1, NCOA1, BCL2More
Chlorpromazinehsa04916Melanogenesis1.33E-021P04049RAF1More
Chlorpromazinehsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Chlorpromazinehsa04919Thyroid hormone signaling pathway6.15E-057P49841, P04049, P22694, P60709, P63261, O60244, Q9NVC6GSK3B, RAF1, PRKACB, ACTB, ACTG1, MED14, MED17More
Chlorpromazinehsa04921Oxytocin signaling pathway1.43E-044P04049, P60660, P60709, P63261RAF1, MYL6, ACTB, ACTG1More
Chlorpromazinehsa04923Regulation of lipolysis in adipocytes4.48E-035Q08828, P51828, P06213, Q13370, P31751ADCY1, ADCY7, INSR, PDE3B, AKT2More
Chlorpromazinehsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Chlorpromazinehsa04925Aldosterone synthesis and secretion6.45E-047P18848, Q08828, P51828, P0DP23, P17252, Q13557, P23634ATF4, ADCY1, ADCY7, CALM1, PRKCA, CAMK2D, ATP2B4More
Chlorpromazinehsa04926Relaxin signaling pathway6.24E-035P18848, P22694, P14780, P04049, P30679ATF4, PRKACB, MMP9, RAF1, GNA15More
Chlorpromazinehsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Chlorpromazinehsa04928Parathyroid hormone synthesis, secretion and action1.99E-021P04049RAF1More
Chlorpromazinehsa04929GnRH secretion4.98E-031P04049RAF1More
Chlorpromazinehsa04930Type II diabetes mellitus3.14E-021P06213INSRMore
Chlorpromazinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Chlorpromazinehsa04932Non-alcoholic fatty liver disease6.73E-059P01375, P49841, P18848, P48023, P01584, P13073, O15239, Q16718, O14521TNF, GSK3B, ATF4, FASLG, IL1B, COX4I1, NDUFA1, NDUFA5, SDHDMore
Chlorpromazinehsa04933AGE-RAGE signaling pathway in diabetic complications2.04E-068Q13485, P01584, P42224, P10415, P31751, P49767, P17252, P19174SMAD4, IL1B, STAT1, BCL2, AKT2, VEGFC, PRKCA, PLCG1More
Chlorpromazinehsa04935Growth hormone synthesis, secretion and action1.77E-027P19174, Q08828, P51828, P04049, P17252, P31751, P42224PLCG1, ADCY1, ADCY7, RAF1, PRKCA, AKT2, STAT1More
Chlorpromazinehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Chlorpromazinehsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Chlorpromazinehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Chlorpromazinehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Chlorpromazinehsa04970Salivary secretion9.40E-058P07550, Q08828, P51828, P22694, P23634, P17252, P0DP23, P49913ADRB2, ADCY1, ADCY7, PRKACB, ATP2B4, PRKCA, CALM1, CAMPMore
Chlorpromazinehsa04971Gastric acid secretion1.02E-022P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa04972Pancreatic secretion1.92E-035P23634, P17252, Q08828, P51828, P62491ATP2B4, PRKCA, ADCY1, ADCY7, RAB11AMore
Chlorpromazinehsa04976Bile secretion1.67E-033O43315, P22694, P08183AQP9, PRKACB, ABCB1More
Chlorpromazinehsa05012Parkinson disease2.53E-025O15239, P13073, P05141, P18848, Q13557NDUFA1, COX4I1, SLC25A5, ATF4, CAMK2DMore
Chlorpromazinehsa05014Amyotrophic lateral sclerosis2.98E-023P36542, P60709, P63261ATP5C1, ACTB, ACTG1More
Chlorpromazinehsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Chlorpromazinehsa05017Spinocerebellar ataxia3.80E-038P17252, O75460, Q8TB72, O15399, P31751, P28070, P43686, O00232PRKCA, ERN1, PUM2, GRIN2D, AKT2, PSMB4, PSMC4, PSMD12More
Chlorpromazinehsa05020Prion disease3.73E-0411P13591, P01584, P11142, O15239, Q16718, O14521, P13073, P18848, P05141, P49841, Q16539NCAM1, IL1B, HSPA8, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, SLC25A5, GSK3B, MAPK14More
Chlorpromazinehsa05022Pathways of neurodegeneration - multiple diseases1.47E-0312P49841, O15239, Q16718, O14521, P13073, P18848, Q13561, P05141, Q16539, P01584, Q08752, Q13557GSK3B, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, DCTN2, SLC25A5, MAPK14, IL1B, PPID, CAMK2DMore
Chlorpromazinehsa05031Amphetamine addiction3.62E-037O15399, P0DP23, Q13557, P22694, P18848, P17252, Q13547GRIN2D, CALM1, CAMK2D, PRKACB, ATF4, PRKCA, HDAC1More
Chlorpromazinehsa05032Morphine addiction4.08E-025Q08828, P51828, P62873, Q13370, P17252ADCY1, ADCY7, GNB1, PDE3B, PRKCAMore
Chlorpromazinehsa05034Alcoholism1.81E-068Q13547, P04049, Q93077, P58876, P62807, Q16778, O60814, P68431HDAC1, RAF1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Chlorpromazinehsa05100Bacterial invasion of epithelial cells7.49E-045Q14141, P60709, P63261, Q05397, Q96JJ3SEPT6, ACTB, ACTG1, PTK2, ELMO2More
Chlorpromazinehsa05110Vibrio cholerae infection3.95E-032P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa05131Shigellosis6.67E-0412P01375, O00463, Q04759, Q9UDY8, Q9H1Y0, P60709, P63261, P20810, O43524, P07384, P10415, Q96A32TNF, TRAF5, PRKCQ, MALT1, ATG5, ACTB, ACTG1, CAST, FOXO3, CAPN1, BCL2, MYLPFMore
Chlorpromazinehsa05132Salmonella infection2.26E-0414P51617, P01584, P08238, P04049, Q96RF0, Q13489, P10415, P08575, O75369, Q13561, Q13509, P68371, P49754, Q9NP90IRAK1, IL1B, HSP90AB1, RAF1, SNAG1, BIRC3, BCL2, PTPRC, FLNB, DCTN2, TUBB3, TUBB2C, VPS41, RAB9BMore
Chlorpromazinehsa05133Pertussis6.00E-056P0DP23, P01584, P23528, P09871, P0C0L4, P51617CALM1, IL1B, CFL1, C1S, C4A, IRAK1More
Chlorpromazinehsa05134Legionellosis1.28E-023P01584, P68104, P11142IL1B, EEF1A1, HSPA8More
Chlorpromazinehsa05135Yersinia infection6.16E-047P60709, P63261, Q05397, Q16513, P51812, Q02750, Q96JJ3ACTB, ACTG1, PTK2, PKN2, RPS6KA3, MAP2K1, ELMO2More
Chlorpromazinehsa05140Leishmaniasis2.58E-025P14598, O60603, P25963, P29350, Q15080NCF1, TLR2, NFKBIA, PTPN6, NCF4More
Chlorpromazinehsa05143African trypanosomiasis1.93E-047P01375, P01584, P69905, P68871, P48023, P17252, P01042TNF, IL1B, HBA2, HBB, FASLG, PRKCA, KNG1More
Chlorpromazinehsa05144Malaria6.73E-066P69905, P68871, O60603, P01375, P35443, P26718HBA2, HBB, TLR2, TNF, THBS4, KLRK1More
Chlorpromazinehsa05145Toxoplasmosis5.28E-059P51617, P10415, Q13489, P23458, P42224, P31751, P11142, P29965, Q13651IRAK1, BCL2, BIRC3, JAK1, STAT1, AKT2, HSPA8, CD40LG, IL10RAMore
Chlorpromazinehsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Chlorpromazinehsa05150Staphylococcus aureus infection8.69E-045P21730, P21462, O75015, P12838, P49913C5AR1, FPR1, FCGR3B, DEFA4, CAMPMore
Chlorpromazinehsa05152Tuberculosis1.17E-038P04049, O75015, P48382, O60603, P01375, P10415, P49913, Q9UDY8RAF1, FCGR3B, RFX5, TLR2, TNF, BCL2, CAMP, MALT1More
Chlorpromazinehsa05160Hepatitis C1.40E-035P60033, P04049, P49841, P01375, P48023CD81, RAF1, GSK3B, TNF, FASLGMore
Chlorpromazinehsa05161Hepatitis B2.85E-0511P17252, P04049, P18848, P23458, Q13485, P31751, P10415, P27348, P01568, P42224, P51617PRKCA, RAF1, ATF4, JAK1, SMAD4, AKT2, BCL2, YWHAQ, IFNA21, STAT1, IRAK1More
Chlorpromazinehsa05162Measles2.45E-0510P51617, P01568, P23458, P42224, P14784, P31751, P11142, P01584, Q9NP90, P10415IRAK1, IFNA21, JAK1, STAT1, IL2RB, AKT2, HSPA8, IL1B, RAB9B, BCL2More
Chlorpromazinehsa05163Human cytomegalovirus infection2.33E-0315P31751, P04049, P62873, P0DP23, Q8NHW4, Q08828, P51828, P23458, P01584, P61073, P17252, Q13651, P18848, P61769, P01568AKT2, RAF1, GNB1, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, IL1B, CXCR4, PRKCA, IL10RA, ATF4, B2M, IFNA21More
Chlorpromazinehsa05164Influenza A8.97E-044P48551, P04049, P60709, P63261IFNAR2, RAF1, ACTB, ACTG1More
Chlorpromazinehsa05167Kaposi sarcoma-associated herpesvirus infection3.15E-021P04049RAF1More
Chlorpromazinehsa05168Herpes simplex virus 1 infection2.45E-0518P01568, P01584, Q9UBU9, P23458, P42224, Q07955, Q01130, Q13243, Q13489, P51617, P61769, P31751, Q13398, Q6P280, Q03923, Q9UDV6, P10415, Q14232IFNA21, IL1B, NXF1, JAK1, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, IRAK1, B2M, AKT2, ZNF211, ZNF529, ZNF85, ZNF212, BCL2, EIF2B1More
Chlorpromazinehsa05170Human immunodeficiency virus 1 infection1.46E-0513P31751, P04049, P62873, P0DP23, P61073, P17252, P61769, P01568, P51617, P19174, P23528, P10415, Q9Y6Q5AKT2, RAF1, GNB1, CALM1, CXCR4, PRKCA, B2M, IFNA21, IRAK1, PLCG1, CFL1, BCL2, AP1M2More
Chlorpromazinehsa05171Coronavirus disease - COVID-196.98E-0512P01584, P62753, P25398, P62249, P40429, P36578, P32969, P27635, Q07020, P18077, P05386, P62829IL1B, RPS6, RPS12, RPS16, RPL13A, RPL4, RPL9, RPL10, RPL18, RPL35A, RPLP1, RPL23More
Chlorpromazinehsa05200Pathways in cancer4.30E-0928P23458, P08238, P42224, P19174, Q15311, P17252, P43246, Q13485, P14923, P10415, Q13489, P49767, P31751, Q08828, P51828, P62873, P61073, P78417, O75293, Q15788, P0DP23, Q13557, O43521, P01568, P14784, P16871, P00734, P01042JAK1, HSP90AB1, STAT1, PLCG1, RALBP1, PRKCA, MSH2, SMAD4, JUP, BCL2, BIRC3, VEGFC, AKT2, ADCY1, ADCY7, GNB1, CXCR4, GSTO1, GADD45B, NCOA1, CALM1, CAMK2D, BCL2L11, IFNA21, IL2RB, IL7R, F2, KNG1More
Chlorpromazinehsa05202Transcriptional misregulation in cancer1.62E-0315Q15532, P41732, P14780, P27930, P14923, Q16548, P11215, Q13077, O15550, P35226, P05164, P08246, Q13547, P12980, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, BCL2A1, ITGAM, TRAF1, UTX, BMI1, MPO, ELA2, HDAC1, LYL1, GADD45AMore
Chlorpromazinehsa05203Viral carcinogenesis1.22E-036Q13547, Q15283, P58876, P62807, Q16778, O60814HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12More
Chlorpromazinehsa05204Chemical carcinogenesis4.02E-055P00325, P09211, P78417, P11712, P33260ADH1B, GSTP1, GSTO1, CYP2C9, CYP2C18More
Chlorpromazinehsa05205Proteoglycans in cancer1.09E-026P04049, P14780, P01375, P23588, Q13635, P22694RAF1, MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Chlorpromazinehsa05206MicroRNAs in cancer4.38E-033P15311, P63279, P04049VIL2, UBE2I, RAF1More
Chlorpromazinehsa05210Colorectal cancer1.66E-021P04049RAF1More
Chlorpromazinehsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Chlorpromazinehsa05212Pancreatic cancer1.15E-037P31751, P04049, Q15311, P23458, P42224, Q13485, O75293AKT2, RAF1, RALBP1, JAK1, STAT1, SMAD4, GADD45BMore
Chlorpromazinehsa05213Endometrial cancer9.95E-031P04049RAF1More
Chlorpromazinehsa05214Glioma3.96E-067P0DP23, Q13557, P17252, P04049, P31751, P19174, O75293CALM1, CAMK2D, PRKCA, RAF1, AKT2, PLCG1, GADD45BMore
Chlorpromazinehsa05215Prostate cancer1.33E-021P04049RAF1More
Chlorpromazinehsa05218Melanoma6.63E-031P04049RAF1More
Chlorpromazinehsa05219Bladder cancer4.98E-031P04049RAF1More
Chlorpromazinehsa05220Chronic myeloid leukemia9.95E-031P04049RAF1More
Chlorpromazinehsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Chlorpromazinehsa05223Non-small cell lung cancer6.63E-031P04049RAF1More
Chlorpromazinehsa05224Breast cancer1.49E-021P04049RAF1More
Chlorpromazinehsa05225Hepatocellular carcinoma2.85E-033P04049, P60709, P63261RAF1, ACTB, ACTG1More
Chlorpromazinehsa05226Gastric cancer8.29E-031P04049RAF1More
Chlorpromazinehsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Chlorpromazinehsa05231Choline metabolism in cancer1.33E-021P04049RAF1More
Chlorpromazinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.66E-021P04049RAF1More
Chlorpromazinehsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Chlorpromazinehsa05322Systemic lupus erythematosus4.80E-067P09871, Q93077, P58876, P62807, Q16778, O60814, P68431C1S, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Chlorpromazinehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Chlorpromazinehsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Chlorpromazinehsa05340Primary immunodeficiency2.68E-022P11912, P07766CD79A, CD3EMore
Chlorpromazinehsa05410Hypertrophic cardiomyopathy1.02E-022P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa05412Arrhythmogenic right ventricular cardiomyopathy3.44E-033P54284, P60709, P63261CACNB3, ACTB, ACTG1More
Chlorpromazinehsa05414Dilated cardiomyopathy1.73E-022P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa05415Diabetic cardiomyopathy1.02E-038P05141, O15239, Q16718, O14521, P13073, Q16539, P49841, Q13557SLC25A5, NDUFA1, NDUFA5, SDHD, COX4I1, MAPK14, GSK3B, CAMK2DMore
Chlorpromazinehsa05416Viral myocarditis8.96E-032P60709, P63261ACTB, ACTG1More
Chlorpromazinehsa05418Fluid shear stress and atherosclerosis3.64E-038P14598, P78417, P60709, P63261, P10415, P0DP23, P08238, Q92974NCF1, GSTO1, ACTB, ACTG1, BCL2, CALM1, HSP90AB1, ARHGEF2More
Promazinehsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Promazinehsa00040Pentose and glucuronate interconversions4.00E-021P15121AKR1B1More
Promazinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Promazinehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Promazinehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Promazinehsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Promazinehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Promazinehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Promazinehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Promazinehsa00620Pyruvate metabolism3.90E-022P07195, P11766LDHB, ADH5More
Promazinehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Promazinehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Promazinehsa00790Folate biosynthesis2.02E-021P15121AKR1B1More
Promazinehsa00970Aminoacyl-tRNA biosynthesis2.12E-021P14868DARSMore
Promazinehsa00980Metabolism of xenobiotics by cytochrome P4506.38E-043P78417, P09211, P11712GSTO1, GSTP1, CYP2C9More
Promazinehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Promazinehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Promazinehsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Promazinehsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Promazinehsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Promazinehsa01522Endocrine resistance2.16E-021P04049RAF1More
Promazinehsa02010ABC transporters2.17E-033P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Promazinehsa03010Ribosome1.08E-0411P62753, P25398, P32969, P40429, P62829, Q07020, P18077, P36578, P27635, P05386, P62249RPS6, RPS12, RPL9, RPL13A, RPL23, RPL18, RPL35A, RPL4, RPL10, RPLP1, RPS16More
Promazinehsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Promazinehsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Promazinehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Promazinehsa03060Protein export4.46E-032Q15070, O76094OXA1L, SRP72More
Promazinehsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Promazinehsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Promazinehsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Promazinehsa04014Ras signaling pathway3.65E-021P04049RAF1More
Promazinehsa04015Rap1 signaling pathway2.99E-021P04049RAF1More
Promazinehsa04022cGMP-PKG signaling pathway3.15E-021P04049RAF1More
Promazinehsa04024cAMP signaling pathway2.49E-021P04049RAF1More
Promazinehsa04062Chemokine signaling pathway3.98E-021P04049RAF1More
Promazinehsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Promazinehsa04071Sphingolipid signaling pathway3.02E-059P04049, P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2RAF1, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Promazinehsa04072Phospholipase D signaling pathway2.82E-021P04049RAF1More
Promazinehsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Promazinehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Promazinehsa04140Autophagy - animal2.82E-021P04049RAF1More
Promazinehsa04141Protein processing in endoplasmic reticulum4.88E-024P18848, O60337, P11142, P07900ATF4, MARH6, HSPA8, HSP90AA1More
Promazinehsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Promazinehsa04150mTOR signaling pathway2.32E-021P04049RAF1More
Promazinehsa04210Apoptosis3.64E-035O76075, P01375, Q9NR28, Q16548, P04049DFFB, TNF, DIABLO, BCL2A1, RAF1More
Promazinehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Promazinehsa04217Necroptosis4.24E-0510P01375, P48023, Q14765, P07900, P15104, P05141, P01584, P0C0S5, Q99878, Q13557TNF, FASLG, STAT4, HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC14, CAMK2DMore
Promazinehsa04218Cellular senescence2.49E-021P04049RAF1More
Promazinehsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Promazinehsa04270Vascular smooth muscle contraction2.32E-021P04049RAF1More
Promazinehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Promazinehsa04360Axon guidance2.49E-021P04049RAF1More
Promazinehsa04370VEGF signaling pathway8.29E-031P04049RAF1More
Promazinehsa04371Apelin signaling pathway2.65E-021P04049RAF1More
Promazinehsa04510Focal adhesion3.48E-021P04049RAF1More
Promazinehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Promazinehsa04540Gap junction1.33E-021P04049RAF1More
Promazinehsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P04049RAF1More
Promazinehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Promazinehsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Promazinehsa04613Neutrophil extracellular trap formation1.63E-0723P04049, P11215, O60603, P05164, P08246, Q9UM07, Q13547, P04908, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539RAF1, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Promazinehsa04625C-type lectin receptor signaling pathway1.49E-021P04049RAF1More
Promazinehsa04630JAK-STAT signaling pathway1.49E-021P04049RAF1More
Promazinehsa04650Natural killer cell mediated cytotoxicity2.93E-058P01375, P20963, P04049, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, RAF1, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Promazinehsa04657IL-17 signaling pathway5.66E-0510P07900, O00463, Q16539, P49841, P19875, P14780, Q9UJX4, P80188, P01375, P01584HSP90AA1, TRAF5, MAPK14, GSK3B, CXCL2, MMP9, ANAPC5, LCN2, TNF, IL1BMore
Promazinehsa04660T cell receptor signaling pathway1.66E-021P04049RAF1More
Promazinehsa04662B cell receptor signaling pathway9.95E-031P04049RAF1More
Promazinehsa04664Fc epsilon RI signaling pathway1.16E-021P04049RAF1More
Promazinehsa04666Fc gamma R-mediated phagocytosis2.32E-021P04049RAF1More
Promazinehsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Promazinehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Promazinehsa04720Long-term potentiation1.66E-021P04049RAF1More
Promazinehsa04722Neurotrophin signaling pathway7.10E-034P04049, P49841, O43524, P48023RAF1, GSK3B, FOXO3, FASLGMore
Promazinehsa04726Serotonergic synapse1.33E-021P04049RAF1More
Promazinehsa04730Long-term depression1.16E-021P04049RAF1More
Promazinehsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Promazinehsa04742Taste transduction1.01E-021P30939HTR1FMore
Promazinehsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Promazinehsa04910Insulin signaling pathway2.51E-034P22694, P06737, P04049, P49841PRKACB, PYGL, RAF1, GSK3BMore
Promazinehsa04912GnRH signaling pathway1.82E-021P04049RAF1More
Promazinehsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Promazinehsa04914Progesterone-mediated oocyte maturation2.16E-021P04049RAF1More
Promazinehsa04915Estrogen signaling pathway2.99E-021P04049RAF1More
Promazinehsa04916Melanogenesis1.33E-021P04049RAF1More
Promazinehsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Promazinehsa04919Thyroid hormone signaling pathway6.83E-045P49841, P04049, P22694, O60244, Q9NVC6GSK3B, RAF1, PRKACB, MED14, MED17More
Promazinehsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Promazinehsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Promazinehsa04926Relaxin signaling pathway6.24E-035P18848, P22694, P14780, P04049, P30679ATF4, PRKACB, MMP9, RAF1, GNA15More
Promazinehsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Promazinehsa04928Parathyroid hormone synthesis, secretion and action1.99E-021P04049RAF1More
Promazinehsa04929GnRH secretion4.98E-031P04049RAF1More
Promazinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Promazinehsa04932Non-alcoholic fatty liver disease6.73E-059P01375, P49841, P18848, P48023, P01584, P13073, O15239, Q16718, O14521TNF, GSK3B, ATF4, FASLG, IL1B, COX4I1, NDUFA1, NDUFA5, SDHDMore
Promazinehsa04935Growth hormone synthesis, secretion and action2.16E-021P04049RAF1More
Promazinehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Promazinehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Promazinehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Promazinehsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Promazinehsa04976Bile secretion1.67E-033O43315, P22694, P08183AQP9, PRKACB, ABCB1More
Promazinehsa05012Parkinson disease2.53E-025O15239, P13073, P05141, P18848, Q13557NDUFA1, COX4I1, SLC25A5, ATF4, CAMK2DMore
Promazinehsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Promazinehsa05020Prion disease3.73E-0411P13591, P01584, P11142, O15239, Q16718, O14521, P13073, P18848, P05141, P49841, Q16539NCAM1, IL1B, HSPA8, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, SLC25A5, GSK3B, MAPK14More
Promazinehsa05022Pathways of neurodegeneration - multiple diseases1.47E-0312P49841, O15239, Q16718, O14521, P13073, P18848, Q13561, P05141, Q16539, P01584, Q08752, Q13557GSK3B, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, DCTN2, SLC25A5, MAPK14, IL1B, PPID, CAMK2DMore
Promazinehsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Promazinehsa05034Alcoholism1.81E-068Q13547, P04049, Q93077, P58876, P62807, Q16778, O60814, P68431HDAC1, RAF1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Promazinehsa05132Salmonella infection4.98E-021P04049RAF1More
Promazinehsa05133Pertussis4.20E-021P0C0L4C4AMore
Promazinehsa05134Legionellosis1.28E-023P01584, P68104, P11142IL1B, EEF1A1, HSPA8More
Promazinehsa05143African trypanosomiasis7.50E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Promazinehsa05144Malaria1.44E-035P69905, P68871, P01375, P35443, P26718HBA2, HBB, TNF, THBS4, KLRK1More
Promazinehsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Promazinehsa05152Tuberculosis3.98E-021P04049RAF1More
Promazinehsa05160Hepatitis C1.40E-035P60033, P04049, P49841, P01375, P48023CD81, RAF1, GSK3B, TNF, FASLGMore
Promazinehsa05161Hepatitis B1.99E-021P04049RAF1More
Promazinehsa05162Measles4.02E-023P11142, P01584, Q9NP90HSPA8, IL1B, RAB9BMore
Promazinehsa05163Human cytomegalovirus infection4.98E-021P04049RAF1More
Promazinehsa05164Influenza A3.65E-021P04049RAF1More
Promazinehsa05167Kaposi sarcoma-associated herpesvirus infection3.15E-021P04049RAF1More
Promazinehsa05170Human immunodeficiency virus 1 infection3.48E-021P04049RAF1More
Promazinehsa05171Coronavirus disease - COVID-196.98E-0512P01584, P62753, P25398, P62249, P40429, P36578, P32969, P27635, Q07020, P18077, P05386, P62829IL1B, RPS6, RPS12, RPS16, RPL13A, RPL4, RPL9, RPL10, RPL18, RPL35A, RPLP1, RPL23More
Promazinehsa05202Transcriptional misregulation in cancer1.62E-0315Q15532, P41732, P14780, P27930, P14923, Q16548, P11215, Q13077, O15550, P35226, P05164, P08246, Q13547, P12980, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, BCL2A1, ITGAM, TRAF1, UTX, BMI1, MPO, ELA2, HDAC1, LYL1, GADD45AMore
Promazinehsa05203Viral carcinogenesis1.22E-036Q13547, Q15283, P58876, P62807, Q16778, O60814HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12More
Promazinehsa05204Chemical carcinogenesis1.09E-033P09211, P78417, P11712GSTP1, GSTO1, CYP2C9More
Promazinehsa05205Proteoglycans in cancer1.09E-026P04049, P14780, P01375, P23588, Q13635, P22694RAF1, MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Promazinehsa05206MicroRNAs in cancer3.15E-021P04049RAF1More
Promazinehsa05210Colorectal cancer1.66E-021P04049RAF1More
Promazinehsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Promazinehsa05212Pancreatic cancer1.16E-021P04049RAF1More
Promazinehsa05213Endometrial cancer9.95E-031P04049RAF1More
Promazinehsa05214Glioma9.95E-031P04049RAF1More
Promazinehsa05215Prostate cancer1.33E-021P04049RAF1More
Promazinehsa05218Melanoma6.63E-031P04049RAF1More
Promazinehsa05219Bladder cancer4.98E-031P04049RAF1More
Promazinehsa05220Chronic myeloid leukemia9.95E-031P04049RAF1More
Promazinehsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Promazinehsa05223Non-small cell lung cancer6.63E-031P04049RAF1More
Promazinehsa05224Breast cancer1.49E-021P04049RAF1More
Promazinehsa05225Hepatocellular carcinoma1.33E-021P04049RAF1More
Promazinehsa05226Gastric cancer8.29E-031P04049RAF1More
Promazinehsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Promazinehsa05231Choline metabolism in cancer1.33E-021P04049RAF1More
Promazinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.66E-021P04049RAF1More
Promazinehsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Promazinehsa05322Systemic lupus erythematosus4.80E-067P09871, Q93077, P58876, P62807, Q16778, O60814, P68431C1S, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Promazinehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Promazinehsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Promazinehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Promazinehsa05415Diabetic cardiomyopathy1.02E-038P05141, O15239, Q16718, O14521, P13073, Q16539, P49841, Q13557SLC25A5, NDUFA1, NDUFA5, SDHD, COX4I1, MAPK14, GSK3B, CAMK2DMore
Triflupromazinehsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Triflupromazinehsa00040Pentose and glucuronate interconversions4.00E-021P15121AKR1B1More
Triflupromazinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Triflupromazinehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Triflupromazinehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Triflupromazinehsa00500Starch and sucrose metabolism1.67E-022O43451, P06737MGAM, PYGLMore
Triflupromazinehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Triflupromazinehsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Triflupromazinehsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Triflupromazinehsa00730Thiamine metabolism5.29E-032P05186, P24666ALPL, ACP1More
Triflupromazinehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Triflupromazinehsa00790Folate biosynthesis2.02E-021P15121AKR1B1More
Triflupromazinehsa00980Metabolism of xenobiotics by cytochrome P4506.38E-043P78417, P09211, P11712GSTO1, GSTP1, CYP2C9More
Triflupromazinehsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Triflupromazinehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Triflupromazinehsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Triflupromazinehsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Triflupromazinehsa02010ABC transporters2.17E-033P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Triflupromazinehsa03010Ribosome1.08E-0411P62753, P25398, P32969, P40429, P62829, Q07020, P18077, P36578, P27635, P05386, P62249RPS6, RPS12, RPL9, RPL13A, RPL23, RPL18, RPL35A, RPL4, RPL10, RPLP1, RPS16More
Triflupromazinehsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Triflupromazinehsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Triflupromazinehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Triflupromazinehsa04071Sphingolipid signaling pathway6.19E-058P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Triflupromazinehsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Triflupromazinehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Triflupromazinehsa04141Protein processing in endoplasmic reticulum4.88E-024P18848, O60337, P11142, P07900ATF4, MARH6, HSPA8, HSP90AA1More
Triflupromazinehsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Triflupromazinehsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Triflupromazinehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Triflupromazinehsa04217Necroptosis4.24E-0510P01375, P48023, Q14765, P07900, P15104, P05141, P01584, P0C0S5, Q99878, Q13557TNF, FASLG, STAT4, HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC14, CAMK2DMore
Triflupromazinehsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Triflupromazinehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Triflupromazinehsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
Triflupromazinehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Triflupromazinehsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Triflupromazinehsa04613Neutrophil extracellular trap formation2.22E-0622P11215, O60603, P05164, P08246, Q9UM07, Q13547, P04908, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Triflupromazinehsa04650Natural killer cell mediated cytotoxicity5.05E-047P01375, P20963, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Triflupromazinehsa04657IL-17 signaling pathway5.66E-0510P07900, O00463, Q16539, P49841, P19875, P14780, Q9UJX4, P80188, P01375, P01584HSP90AA1, TRAF5, MAPK14, GSK3B, CXCL2, MMP9, ANAPC5, LCN2, TNF, IL1BMore
Triflupromazinehsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Triflupromazinehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Triflupromazinehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Triflupromazinehsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Triflupromazinehsa04742Taste transduction1.01E-021P30939HTR1FMore
Triflupromazinehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Triflupromazinehsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Triflupromazinehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Triflupromazinehsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Triflupromazinehsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Triflupromazinehsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Triflupromazinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Triflupromazinehsa04932Non-alcoholic fatty liver disease6.73E-059P01375, P49841, P18848, P48023, P01584, P13073, O15239, Q16718, O14521TNF, GSK3B, ATF4, FASLG, IL1B, COX4I1, NDUFA1, NDUFA5, SDHDMore
Triflupromazinehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Triflupromazinehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Triflupromazinehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Triflupromazinehsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Triflupromazinehsa04976Bile secretion1.67E-033O43315, P22694, P08183AQP9, PRKACB, ABCB1More
Triflupromazinehsa05012Parkinson disease2.53E-025O15239, P13073, P05141, P18848, Q13557NDUFA1, COX4I1, SLC25A5, ATF4, CAMK2DMore
Triflupromazinehsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Triflupromazinehsa05020Prion disease3.73E-0411P13591, P01584, P11142, O15239, Q16718, O14521, P13073, P18848, P05141, P49841, Q16539NCAM1, IL1B, HSPA8, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, SLC25A5, GSK3B, MAPK14More
Triflupromazinehsa05022Pathways of neurodegeneration - multiple diseases1.47E-0312P49841, O15239, Q16718, O14521, P13073, P18848, Q13561, P05141, Q16539, P01584, Q08752, Q13557GSK3B, NDUFA1, NDUFA5, SDHD, COX4I1, ATF4, DCTN2, SLC25A5, MAPK14, IL1B, PPID, CAMK2DMore
Triflupromazinehsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Triflupromazinehsa05034Alcoholism2.05E-057Q13547, Q93077, P58876, P62807, Q16778, O60814, P68431HDAC1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Triflupromazinehsa05133Pertussis4.20E-021P0C0L4C4AMore
Triflupromazinehsa05134Legionellosis1.28E-023P01584, P68104, P11142IL1B, EEF1A1, HSPA8More
Triflupromazinehsa05143African trypanosomiasis7.50E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Triflupromazinehsa05144Malaria1.44E-035P69905, P68871, P01375, P35443, P26718HBA2, HBB, TNF, THBS4, KLRK1More
Triflupromazinehsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Triflupromazinehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Triflupromazinehsa05162Measles4.02E-023P11142, P01584, Q9NP90HSPA8, IL1B, RAB9BMore
Triflupromazinehsa05171Coronavirus disease - COVID-196.98E-0512P01584, P62753, P25398, P62249, P40429, P36578, P32969, P27635, Q07020, P18077, P05386, P62829IL1B, RPS6, RPS12, RPS16, RPL13A, RPL4, RPL9, RPL10, RPL18, RPL35A, RPLP1, RPL23More
Triflupromazinehsa05202Transcriptional misregulation in cancer1.62E-0315Q15532, P41732, P14780, P27930, P14923, Q16548, P11215, Q13077, O15550, P35226, P05164, P08246, Q13547, P12980, P24522SS18, TSPAN7, MMP9, IL1R2, JUP, BCL2A1, ITGAM, TRAF1, UTX, BMI1, MPO, ELA2, HDAC1, LYL1, GADD45AMore
Triflupromazinehsa05203Viral carcinogenesis1.22E-036Q13547, Q15283, P58876, P62807, Q16778, O60814HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12More
Triflupromazinehsa05204Chemical carcinogenesis1.09E-033P09211, P78417, P11712GSTP1, GSTO1, CYP2C9More
Triflupromazinehsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Triflupromazinehsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Triflupromazinehsa05322Systemic lupus erythematosus4.80E-067P09871, Q93077, P58876, P62807, Q16778, O60814, P68431C1S, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Triflupromazinehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Triflupromazinehsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Triflupromazinehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Triflupromazinehsa05415Diabetic cardiomyopathy1.02E-038P05141, O15239, Q16718, O14521, P13073, Q16539, P49841, Q13557SLC25A5, NDUFA1, NDUFA5, SDHD, COX4I1, MAPK14, GSK3B, CAMK2DMore

Community members of Promazine (SDC: 5.50)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P14416DRD2D(2) dopamine receptorReported00.060410.47792.5081
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
P09211GSTP1Glutathione SNonetransferase PPredicted00.32040.35230.45661.3213
P04156PRNPMajor prion proteinPredicted00.59090.173700.6429
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P22748CA4Carbonic anhydrase 4Predicted00.00560.82670.16091.8171
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P02768ALBAlbuminPredicted10.28480.91110.08572.0502
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P37840SNCAAlphaNonesynucleinPredicted10.08530.13240.33210.6395
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
DRD2P14416Ki160
DRD2P14416Ki161.29
DRD2P14416Ki300
DRD2P14416IC501
DRD2P14416IC503
DRD2P14416IC5012
DRD2P14416Ki0.66
DRD2P14416Ki1.2
DRD2P14416Ki1.3
DRD2P14416Ki2.8