| Proguanil | hsa00053 | Ascorbate and aldarate metabolism | 4.93E-02 | 1 | P14550 | AKR1A1 | More | |
| Proguanil | hsa00230 | Purine metabolism | 4.02E-02 | 2 | P31350, P21589 | RRM2, NT5E | More | |
| Proguanil | hsa00240 | Pyrimidine metabolism | 2.54E-04 | 3 | P31350, P21589, P04818 | RRM2, NT5E, TYMS | More | |
| Proguanil | hsa00565 | Ether lipid metabolism | 4.93E-02 | 1 | Q8N661 | TMEM86B | More | |
| Proguanil | hsa00670 | One carbon pool by folate | 3.62E-02 | 1 | P00374 | DHFR | More | |
| Proguanil | hsa00790 | Folate biosynthesis | 3.62E-02 | 1 | P00374 | DHFR | More | |
| Proguanil | hsa01523 | Antifolate resistance | 6.06E-03 | 2 | Q92820, P04818 | GGH, TYMS | More | |
| Proguanil | hsa02010 | ABC transporters | 4.93E-02 | 1 | Q8IZY2 | ABCA7 | More | |
| Proguanil | hsa04110 | Cell cycle | 2.34E-02 | 3 | P06493, O60566, P33981 | CDK1, BUB1B, TTK | More | |
| Proguanil | hsa04115 | p53 signaling pathway | 3.34E-02 | 2 | P31350, P06493 | RRM2, CDK1 | More | |
| Proguanil | hsa04213 | Longevity regulating pathway - multiple species | 2.85E-02 | 2 | Q9Y4H2, Q13547 | IRS2, HDAC1 | More | |
| Proguanil | hsa04610 | Complement and coagulation cascades | 2.33E-03 | 1 | P0C0L4 | C4A | More | |
| Proguanil | hsa04613 | Neutrophil extracellular trap formation | 1.23E-03 | 5 | P11215, Q13547, P58876, Q16778, O60814 | ITGAM, HDAC1, H2BC5, HIST2H2BE, H2BC12 | More | |
| Proguanil | hsa04964 | Proximal tubule bicarbonate reclamation | 4.93E-02 | 1 | P00918 | CA2 | More | |
| Proguanil | hsa04966 | Collecting duct acid secretion | 4.93E-02 | 1 | P00918 | CA2 | More | |
| Proguanil | hsa05034 | Alcoholism | 1.30E-04 | 6 | Q13547, P62879, Q9BTM1, P58876, Q16778, O60814 | HDAC1, GNB2, H2AFJ, H2BC5, HIST2H2BE, H2BC12 | More | |
| Proguanil | hsa05133 | Pertussis | 4.20E-02 | 1 | P0C0L4 | C4A | More | |
| Proguanil | hsa05143 | African trypanosomiasis | 1.31E-02 | 2 | P69905, P68871 | HBA2, HBB | More | |
| Proguanil | hsa05144 | Malaria | 3.09E-02 | 2 | P69905, P68871 | HBA2, HBB | More | |
| Proguanil | hsa05200 | Pathways in cancer | 4.70E-02 | 3 | P17301, P20585, P62879 | ITGA2, MSH3, GNB2 | More | |
| Proguanil | hsa05202 | Transcriptional misregulation in cancer | 1.24E-02 | 4 | P27930, P11215, Q13547, P12980 | IL1R2, ITGAM, HDAC1, LYL1 | More | |
| Proguanil | hsa05203 | Viral carcinogenesis | 6.44E-03 | 4 | Q13547, P58876, Q16778, O60814 | HDAC1, H2BC5, HIST2H2BE, H2BC12 | More | |
| Proguanil | hsa05322 | Systemic lupus erythematosus | 1.18E-02 | 3 | P58876, Q16778, O60814 | H2BC5, HIST2H2BE, H2BC12 | More | |
| Proguanil | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.93E-02 | 1 | P54284 | CACNB3 | More | |
