PharmaCoNets of Procaterol (SPCN: 21.86 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Procaterolhsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Procaterolhsa00190Oxidative phosphorylation1.07E-023Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Procaterolhsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Procaterolhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Procaterolhsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Procaterolhsa03040Spliceosome2.09E-027Q14562, O43143, O75940, O75494, Q07955, Q01130, Q13243DHX8, DHX15, SMNDC1, FUSIP1, SFRS1, SFRS2, SFRS5More
Procaterolhsa04014Ras signaling pathway1.70E-027P20827, Q9NRA1, P49767, P17252, P0DP23, P62873, P19174EFNA1, PDGFC, VEGFC, PRKCA, CALM1, GNB1, PLCG1More
Procaterolhsa04015Rap1 signaling pathway4.58E-026P20827, Q9NRA1, P49767, P0DP23, P17252, P19174EFNA1, PDGFC, VEGFC, CALM1, PRKCA, PLCG1More
Procaterolhsa04020Calcium signaling pathway2.01E-026P17252, P19174, P0DP23, P20020, Q9NRA1, P49767PRKCA, PLCG1, CALM1, ATP2B1, PDGFC, VEGFCMore
Procaterolhsa04070Phosphatidylinositol signaling system4.40E-024P19174, P0DP23, P23743, P17252PLCG1, CALM1, DGKA, PRKCAMore
Procaterolhsa04071Sphingolipid signaling pathway1.19E-024P21453, Q9H228, P01375, Q13362S1PR1, EDG8, TNF, PPP2R5CMore
Procaterolhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Procaterolhsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Procaterolhsa04145Phagosome4.68E-025Q15080, P14598, Q13509, P68371, Q13488NCF4, NCF1, TUBB3, TUBB2C, TCIRG1More
Procaterolhsa04217Necroptosis1.07E-0311P01375, P01568, P48023, P42224, Q14765, P08238, Q6FI13, Q99878, Q93077, O43633, Q08752TNF, IFNA21, FASLG, STAT1, STAT4, HSP90AB1, H2AC18; H2AC19, H2AC14, HIST1H2AC, CHMP2A, PPIDMore
Procaterolhsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Procaterolhsa04360Axon guidance2.29E-025P16333, P20827, O95631, P17252, P19174NCK1, EFNA1, NTN1, PRKCA, PLCG1More
Procaterolhsa04540Gap junction1.67E-024P17252, Q13509, P68371, Q9NRA1PRKCA, TUBB3, TUBB2C, PDGFCMore
Procaterolhsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Procaterolhsa04623Cytosolic DNA-sensing pathway3.29E-022P01568, P25963IFNA21, NFKBIAMore
Procaterolhsa04650Natural killer cell mediated cytotoxicity5.05E-047P01375, P20963, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Procaterolhsa04657IL-17 signaling pathway2.05E-039P25963, P08238, Q07955, P19875, P14780, P04141, P80188, P01375, P06702NFKBIA, HSP90AB1, SFRS1, CXCL2, MMP9, CSF2, LCN2, TNF, S100A9More
Procaterolhsa04660T cell receptor signaling pathway3.80E-026P04141, P25963, P10747, P19174, P16333, P29350CSF2, NFKBIA, CD28, PLCG1, NCK1, PTPN6More
Procaterolhsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Procaterolhsa04713Circadian entrainment3.32E-024P0DP23, P17252, P62873, O15055CALM1, PRKCA, GNB1, PER2More
Procaterolhsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Procaterolhsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Procaterolhsa04742Taste transduction1.01E-021P30939HTR1FMore
Procaterolhsa04744Phototransduction1.18E-022P62873, P0DP23GNB1, CALM1More
Procaterolhsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Procaterolhsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Procaterolhsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Procaterolhsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Procaterolhsa04932Non-alcoholic fatty liver disease2.74E-023P01375, P49841, P48023TNF, GSK3B, FASLGMore
Procaterolhsa04933AGE-RAGE signaling pathway in diabetic complications1.72E-025P42224, Q12778, P49767, P17252, P19174STAT1, FOXO1, VEGFC, PRKCA, PLCG1More
Procaterolhsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Procaterolhsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Procaterolhsa05012Parkinson disease3.12E-026Q16718, O14521, P19174, P0DP23, Q13509, P68371NDUFA5, SDHD, PLCG1, CALM1, TUBB3, TUBB2CMore
Procaterolhsa05022Pathways of neurodegeneration - multiple diseases2.29E-029Q13509, P68371, Q16718, O14521, Q13561, P19174, P17252, Q08752, P0DP23TUBB3, TUBB2C, NDUFA5, SDHD, DCTN2, PLCG1, PRKCA, PPID, CALM1More
Procaterolhsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Procaterolhsa05110Vibrio cholerae infection1.98E-023Q13488, P17252, P19174TCIRG1, PRKCA, PLCG1More
Procaterolhsa05132Salmonella infection1.70E-028P25963, P08238, P04406, O75369, Q13561, Q13509, P68371, P49754NFKBIA, HSP90AB1, GAPDH, FLNB, DCTN2, TUBB3, TUBB2C, VPS41More
Procaterolhsa05140Leishmaniasis1.72E-025P14598, P42224, P25963, P29350, Q15080NCF1, STAT1, NFKBIA, PTPN6, NCF4More
Procaterolhsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Procaterolhsa05144Malaria1.91E-023P01375, P35443, P26718TNF, THBS4, KLRK1More
Procaterolhsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Procaterolhsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Procaterolhsa05167Kaposi sarcoma-associated herpesvirus infection5.71E-038P01568, P42224, P25963, P40189, P62873, P19174, P04141, P0DP23IFNA21, STAT1, NFKBIA, IL6ST, GNB1, PLCG1, CSF2, CALM1More
Procaterolhsa05168Herpes simplex virus 1 infection4.15E-0312P25963, P01568, Q9GZY0, P42224, Q07955, Q01130, Q13243, Q13398, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, NXF2; NXF2B, STAT1, SFRS1, SFRS2, SFRS5, ZNF211, ZNF85, ZNF140, ZNF189, ZNF212More
Procaterolhsa05171Coronavirus disease - COVID-191.36E-027P25963, P42224, P01568, P40189, P04141, P19174, P17252NFKBIA, STAT1, IFNA21, IL6ST, CSF2, PLCG1, PRKCAMore
Procaterolhsa05200Pathways in cancer1.75E-0214P08238, P42224, P25963, P19174, P17252, P43246, P14923, P49767, Q12778, P62873, O75293, P0DP23, P01568, P40189HSP90AB1, STAT1, NFKBIA, PLCG1, PRKCA, MSH2, JUP, VEGFC, FOXO1, GNB1, GADD45B, CALM1, IFNA21, IL6STMore
Procaterolhsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Procaterolhsa05214Glioma1.09E-024P0DP23, P17252, P19174, O75293CALM1, PRKCA, PLCG1, GADD45BMore
Procaterolhsa05231Choline metabolism in cancer2.25E-035Q9NRA1, Q9Y259, P19174, P23743, P17252PDGFC, CHKB, PLCG1, DGKA, PRKCAMore
Procaterolhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer2.97E-025P25963, P19174, P29350, P42224, P10747NFKBIA, PLCG1, PTPN6, STAT1, CD28More
Procaterolhsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Procaterolhsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Procaterolhsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Procaterolhsa05415Diabetic cardiomyopathy1.20E-026P17252, P14598, Q15080, Q16718, O14521, P04406PRKCA, NCF1, NCF4, NDUFA5, SDHD, GAPDHMore

Community members of Procaterol (SDC: 2.72)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P07550ADRB2BetaNone2 adrenergic receptorReported00.007110.22052.224
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
Q13370PDE3BcGMPNoneinhibited 3',5'Nonecyclic phosphodiesterase BPredicted00.09060.16140.35580.7239
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
ADRB2P07550Ki33