| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Methylprednisolone | hsa00030 | Pentose phosphate pathway | 8.97E-03 | 1 | P11413 | G6PD | More | | | Methylprednisolone | hsa00052 | Galactose metabolism | 1.03E-02 | 2 | P06280, O43451 | GLA, MGAM | More | | | Methylprednisolone | hsa00053 | Ascorbate and aldarate metabolism | 4.93E-02 | 1 | P14550 | AKR1A1 | More | | | Methylprednisolone | hsa00190 | Oxidative phosphorylation | 8.71E-03 | 3 | Q16718, Q13488, O14521 | NDUFA5, TCIRG1, SDHD | More | | | Methylprednisolone | hsa00480 | Glutathione metabolism | 1.35E-02 | 1 | P11413 | G6PD | More | | | Methylprednisolone | hsa00500 | Starch and sucrose metabolism | 2.00E-03 | 3 | O43451, P46976, P06737 | MGAM, GYG1, PYGL | More | | | Methylprednisolone | hsa00565 | Ether lipid metabolism | 4.93E-02 | 1 | Q8N661 | TMEM86B | More | | | Methylprednisolone | hsa00590 | Arachidonic acid metabolism | 3.85E-02 | 2 | P11712, P09960 | CYP2C9, LTA4H | More | | | Methylprednisolone | hsa00591 | Linoleic acid metabolism | 4.07E-02 | 1 | P11712 | CYP2C9 | More | | | Methylprednisolone | hsa00730 | Thiamine metabolism | 5.29E-03 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Methylprednisolone | hsa00970 | Aminoacyl-tRNA biosynthesis | 1.21E-02 | 1 | P14868 | DARS | More | | | Methylprednisolone | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 9.14E-03 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Methylprednisolone | hsa00982 | Drug metabolism - cytochrome P450 | 9.14E-03 | 2 | P11712, P78417 | CYP2C9, GSTO1 | More | | | Methylprednisolone | hsa00983 | Drug metabolism - other enzymes | 2.44E-02 | 2 | P32320, P05164 | CDA, MPO | More | | | Methylprednisolone | hsa01200 | Carbon metabolism | 2.91E-02 | 1 | P11413 | G6PD | More | | | Methylprednisolone | hsa02010 | ABC transporters | 4.93E-02 | 1 | Q8IZY2 | ABCA7 | More | | | Methylprednisolone | hsa03013 | RNA transport | 3.11E-02 | 2 | P68104, Q14232 | EEF1A1, EIF2B1 | More | | | Methylprednisolone | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 2.00E-02 | 7 | P09341, P25024, P25025, P47992, Q9UBD3, Q13651, P01375 | CXCL1, CXCR1, CXCR2, XCL1, XCL2, IL10RA, TNF | More | | | Methylprednisolone | hsa04064 | NF-kappa B signaling pathway | 1.34E-03 | 8 | P10415, Q13489, Q13546, P29965, Q9UDY8, Q8WV28, Q13315, Q9UNE0 | BCL2, BIRC3, RIPK1, CD40LG, MALT1, BLNK, ATM, EDAR | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P01584 | IL1B | Interleukin-1 beta | P63279 | UBE2I | SUMO-conjugating enzyme UBC9 | 0.815 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 |
| | Methylprednisolone | hsa04070 | Phosphatidylinositol signaling system | 3.47E-02 | 4 | P0DP23, Q14643, P23743, P17252 | CALM1, ITPR1, DGKA, PRKCA | More | | | Methylprednisolone | hsa04071 | Sphingolipid signaling pathway | 2.87E-03 | 7 | P17252, Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2 | PRKCA, EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2 | More | | | Methylprednisolone | hsa04140 | Autophagy - animal | 3.61E-02 | 5 | Q9NQL2, P22694, Q14643, Q9H1Y0, Q04759 | RRAGD, PRKACB, ITPR1, ATG5, PRKCQ | More | | | Methylprednisolone | hsa04141 | Protein processing in endoplasmic reticulum | 3.89E-02 | 2 | P17861, Q9NR31 | XBP1, SAR1A | More | | | Methylprednisolone | hsa04145 | Phagosome | 1.59E-03 | 7 | Q15080, P14598, Q13509, P68371, Q13488, O60603, P13765 | NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, TLR2, HLA-DOB | More | | | Methylprednisolone | hsa04151 | PI3K-Akt signaling pathway | 4.50E-02 | 9 | P25116, P49767, Q13362, P62873, P16144, O60603, P01568, P10415, P17252 | F2R, VEGFC, PPP2R5C, GNB1, ITGB4, TLR2, IFNA21, BCL2, PRKCA | More | | | Methylprednisolone | hsa04210 | Apoptosis | 3.58E-02 | 4 | O76075, P01375, Q9NR28, Q16548 | DFFB, TNF, DIABLO, BCL2A1 | More | | | Methylprednisolone | hsa04211 | Longevity regulating pathway | 1.18E-02 | 3 | Q12778, Q9UEF7, Q96KQ7 | FOXO1, KL, EHMT2 | More | | | Methylprednisolone | hsa04213 | Longevity regulating pathway - multiple species | 2.85E-02 | 2 | Q9Y4H2, Q13547 | IRS2, HDAC1 | More | | | Methylprednisolone | hsa04217 | Necroptosis | 9.70E-04 | 8 | P01568, Q13489, Q13546, P42224, Q6FI13, P10415, O43633, Q08752 | IFNA21, BIRC3, RIPK1, STAT1, H2AC18; H2AC19, BCL2, CHMP2A, PPID | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P01584 | IL1B | Interleukin-1 beta | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | 0.799 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P01584 | IL1B | Interleukin-1 beta | P0C0S5 | H2AFZ | Histone H2A.Z | 0.762 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | Q9H444 | CHMP4B | Charged multivesicular body protein 4b | 0.716 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Methylprednisolone | hsa04261 | Adrenergic signaling in cardiomyocytes | 2.84E-02 | 5 | P09493, Q13362, P0DP23, P17252, P10415 | TPM1, PPP2R5C, CALM1, PRKCA, BCL2 | More | | | Methylprednisolone | hsa04340 | Hedgehog signaling pathway | 3.32E-02 | 2 | P49841, P22694 | GSK3B, PRKACB | More | | | Methylprednisolone | hsa04530 | Tight junction | 3.29E-02 | 3 | P16989, P56750, Q14247 | CSDA, CLDN17, CTTN | More | | | Methylprednisolone | hsa04540 | Gap junction | 1.29E-02 | 4 | P17252, Q13509, P68371, Q14643 | PRKCA, TUBB3, TUBB2C, ITPR1 | More | | | Methylprednisolone | hsa04610 | Complement and coagulation cascades | 2.33E-03 | 1 | P0C0L4 | C4A | More | | | Methylprednisolone | hsa04612 | Antigen processing and presentation | 3.60E-03 | 8 | P13765, P48382, P26715, P26717, Q13241, O43908, P01732, P01375 | HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNF | More | | | Methylprednisolone | hsa04613 | Neutrophil extracellular trap formation | 7.05E-06 | 23 | P17252, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, P14598, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539 | PRKCA, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 |
| | Methylprednisolone | hsa04620 | Toll-like receptor signaling pathway | 4.16E-02 | 2 | Q13546, P01568 | RIPK1, IFNA21 | More | | | Methylprednisolone | hsa04621 | NOD-like receptor signaling pathway | 3.13E-04 | 17 | Q16539, Q14643, P01568, Q13489, P10599, Q9H1Y0, P43490, O00463, Q13546, P29728, Q05823, P01375, P09341, P49913, P59665, P59666, P12838 | MAPK14, ITPR1, IFNA21, BIRC3, TXN, ATG5, PBEF1, TRAF5, RIPK1, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 |
| | Methylprednisolone | hsa04622 | RIG-I-like receptor signaling pathway | 2.39E-02 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Methylprednisolone | hsa04623 | Cytosolic DNA-sensing pathway | 2.20E-03 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Methylprednisolone | hsa04640 | Hematopoietic cell lineage | 1.10E-02 | 9 | P13612, P14778, P27930, P15144, P25063, P09693, P01732, P13765, P01375 | ITGA4, IL1R1, IL1R2, ANPEP, CD24, CD3G, CD8A, HLA-DOB, TNF | More | | | Methylprednisolone | hsa04650 | Natural killer cell mediated cytotoxicity | 3.11E-04 | 9 | P01375, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, P26715 | TNF, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P11511 | CYP19A1 | Aromatase | P16298 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 0.706 | | P11511 | CYP19A1 | Aromatase | P50591 | TNFSF10 | Tumor necrosis factor ligand superfamily member 10 | 0.701 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P11511 | CYP19A1 | Aromatase | Q02750 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | 0.783 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 |
| | Methylprednisolone | hsa04657 | IL-17 signaling pathway | 1.80E-03 | 7 | O00463, Q16539, P49841, P09341, P14780, P80188, P01375 | TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF | More | | | Methylprednisolone | hsa04658 | Th1 and Th2 cell differentiation | 5.94E-04 | 9 | Q04759, P20963, P09693, Q16539, P06239, Q14765, P23771, Q9UL17, P13765 | PRKCQ, CD247, CD3G, MAPK14, LCK, STAT4, GATA3, TBX21, HLA-DOB | More | | | Methylprednisolone | hsa04659 | Th17 cell differentiation | 3.91E-03 | 9 | Q04759, Q16539, P06239, P13765, P14778, Q9UL17, P23771, P09693, P20963 | PRKCQ, MAPK14, LCK, HLA-DOB, IL1R1, TBX21, GATA3, CD3G, CD247 | More | | | Methylprednisolone | hsa04660 | T cell receptor signaling pathway | 6.95E-04 | 11 | P01375, Q04759, O95267, Q08881, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841 | TNF, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3B | More | | | Methylprednisolone | hsa04672 | Intestinal immune network for IgA production | 3.76E-03 | 3 | P29965, P10747, P13765 | CD40LG, CD28, HLA-DOB | More | | | Methylprednisolone | hsa04713 | Circadian entrainment | 2.60E-02 | 4 | P0DP23, P17252, P62873, Q14643 | CALM1, PRKCA, GNB1, ITPR1 | More | | | Methylprednisolone | hsa04720 | Long-term potentiation | 3.89E-02 | 3 | P17252, P0DP23, Q14643 | PRKCA, CALM1, ITPR1 | More | | | Methylprednisolone | hsa04723 | Retrograde endocannabinoid signaling | 1.88E-02 | 4 | Q14643, P17252, P62873, Q16718 | ITPR1, PRKCA, GNB1, NDUFA5 | More | | | Methylprednisolone | hsa04725 | Cholinergic synapse | 1.88E-02 | 4 | Q14643, P17252, P62873, P10415 | ITPR1, PRKCA, GNB1, BCL2 | More | | | Methylprednisolone | hsa04728 | Dopaminergic synapse | 3.55E-02 | 5 | Q14643, P17252, P62873, Q13362, P0DP23 | ITPR1, PRKCA, GNB1, PPP2R5C, CALM1 | More | | | Methylprednisolone | hsa04744 | Phototransduction | 1.02E-02 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | | | Methylprednisolone | hsa04750 | Inflammatory mediator regulation of TRP channels | 3.61E-02 | 5 | P14778, P22694, Q16539, Q14643, Q04759 | IL1R1, PRKACB, MAPK14, ITPR1, PRKCQ | More | | | Methylprednisolone | hsa04910 | Insulin signaling pathway | 2.35E-02 | 3 | P22694, P06737, P49841 | PRKACB, PYGL, GSK3B | More | | | Methylprednisolone | hsa04912 | GnRH signaling pathway | 3.89E-02 | 3 | P17252, Q14643, P0DP23 | PRKCA, ITPR1, CALM1 | More | | | Methylprednisolone | hsa04919 | Thyroid hormone signaling pathway | 7.11E-03 | 4 | P49841, P22694, O60244, Q9NVC6 | GSK3B, PRKACB, MED14, MED17 | More | | | Methylprednisolone | hsa04922 | Glucagon signaling pathway | 3.47E-02 | 4 | Q12778, Q13370, P0DP23, Q14643 | FOXO1, PDE3B, CALM1, ITPR1 | More | | | Methylprednisolone | hsa04924 | Renin secretion | 8.71E-03 | 3 | Q14643, Q13370, P0DP23 | ITPR1, PDE3B, CALM1 | More | | | Methylprednisolone | hsa04931 | Insulin resistance | 1.94E-02 | 3 | P01375, P49841, P06737 | TNF, GSK3B, PYGL | More | | | Methylprednisolone | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 1.27E-02 | 5 | P42224, P10415, Q12778, P49767, P17252 | STAT1, BCL2, FOXO1, VEGFC, PRKCA | More | | | Methylprednisolone | hsa04964 | Proximal tubule bicarbonate reclamation | 4.93E-02 | 1 | P00918 | CA2 | More | | | Methylprednisolone | hsa04966 | Collecting duct acid secretion | 2.07E-03 | 3 | Q13488, P00918, Q9Y666 | TCIRG1, CA2, SLC12A7 | More | | | Methylprednisolone | hsa04975 | Fat digestion and absorption | 2.80E-02 | 1 | O14494 | PLPP1 | More | | | Methylprednisolone | hsa04976 | Bile secretion | 2.44E-02 | 2 | P22694, P08183 | PRKACB, ABCB1 | More | | | Methylprednisolone | hsa05010 | Alzheimer disease | 1.07E-02 | 10 | Q16718, O14521, Q06055, Q14643, P0DP23, Q13509, P68371, Q08752, P17861, P62195 | NDUFA5, SDHD, ATP5G2, ITPR1, CALM1, TUBB3, TUBB2C, PPID, XBP1, PSMC5 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q92542 | NCSTN | Nicastrin | 0.706 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P05496 | ATP5G1 | ATP synthase F(0) complex subunit C1, mitochondrial | 0.733 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.754 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P01584 | IL1B | Interleukin-1 beta | 0.75 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O15169 | AXIN1 | Axin-1 | 0.742 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P45880 | VDAC2 | Voltage-dependent anion-selective channel protein 2 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Methylprednisolone | hsa05012 | Parkinson disease | 5.36E-03 | 9 | Q16718, O14521, Q06055, P17861, P62195, Q14643, P0DP23, Q13509, P68371 | NDUFA5, SDHD, ATP5G2, XBP1, PSMC5, ITPR1, CALM1, TUBB3, TUBB2C | More | | | Methylprednisolone | hsa05014 | Amyotrophic lateral sclerosis | 1.01E-02 | 3 | Q06055, P17861, P62195 | ATP5G2, XBP1, PSMC5 | More | | | Methylprednisolone | hsa05017 | Spinocerebellar ataxia | 1.42E-02 | 2 | P17861, P62195 | XBP1, PSMC5 | More | | | Methylprednisolone | hsa05020 | Prion disease | 1.15E-02 | 7 | Q16718, O14521, Q14643, Q13509, P68371, P14598, Q15080 | NDUFA5, SDHD, ITPR1, TUBB3, TUBB2C, NCF1, NCF4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P01584 | IL1B | Interleukin-1 beta | 0.75 | | P01584 | IL1B | Interleukin-1 beta | P46531 | NOTCH1 | Neurogenic locus notch homolog protein 1 | 0.827 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P46531 | NOTCH1 | Neurogenic locus notch homolog protein 1 | 0.706 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P11142 | HSPA8 | Heat shock cognate 71 kDa protein | 0.766 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P05496 | ATP5G1 | ATP synthase F(0) complex subunit C1, mitochondrial | 0.733 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.754 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P45880 | VDAC2 | Voltage-dependent anion-selective channel protein 2 | 0.708 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P01584 | IL1B | Interleukin-1 beta | Q99941 | CREBL1 | Cyclic AMP-dependent transcription factor ATF-6 beta | 0.704 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q99941 | CREBL1 | Cyclic AMP-dependent transcription factor ATF-6 beta | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 |
| | Methylprednisolone | hsa05022 | Pathways of neurodegeneration - multiple diseases | 1.98E-03 | 13 | Q14643, Q13509, P68371, P10415, Q16718, O14521, Q06055, P17861, Q13561, P17252, Q08752, P0DP23, P62195 | ITPR1, TUBB3, TUBB2C, BCL2, NDUFA5, SDHD, ATP5G2, XBP1, DCTN2, PRKCA, PPID, CALM1, PSMC5 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P01584 | IL1B | Interleukin-1 beta | Q8TEV9 | SMCR8 | Guanine nucleotide exchange protein SMCR8 | 0.705 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 |
| | Methylprednisolone | hsa05034 | Alcoholism | 2.05E-05 | 7 | Q13547, Q93077, P58876, P62807, Q16778, O60814, P68431 | HDAC1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | | Methylprednisolone | hsa05131 | Shigellosis | 2.27E-02 | 8 | P68431, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | Q05655 | PRKCD | Protein kinase C delta type | Q05655 | PRKCD | Protein kinase C delta type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | Q05655 | PRKCD | Protein kinase C delta type | P07737 | PFN1 | Profilin-1 | 0.77 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Methylprednisolone | hsa05132 | Salmonella infection | 5.51E-04 | 10 | Q9UJU2, Q13546, Q13489, P10415, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371 | LEF1, RIPK1, BIRC3, BCL2, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2C | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | Q05655 | PRKCD | Protein kinase C delta type | P84095 | RHOG | Rho-related GTP-binding protein RhoG | 0.71 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | Q05655 | PRKCD | Protein kinase C delta type | P07737 | PFN1 | Profilin-1 | 0.77 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 |
| | Methylprednisolone | hsa05133 | Pertussis | 4.20E-02 | 1 | P0C0L4 | C4A | More | | | Methylprednisolone | hsa05134 | Legionellosis | 5.53E-03 | 2 | Q9NR31, P68104 | SAR1A, EEF1A1 | More | | | Methylprednisolone | hsa05135 | Yersinia infection | 3.72E-02 | 6 | P13612, P06239, Q16539, P01375, P49841, P01732 | ITGA4, LCK, MAPK14, TNF, GSK3B, CD8A | More | | | Methylprednisolone | hsa05140 | Leishmaniasis | 2.45E-04 | 10 | P13612, O75015, P14598, P42224, P13765, O60603, P01375, P29350, Q16539, Q15080 | ITGA4, FCGR3B, NCF1, STAT1, HLA-DOB, TLR2, TNF, PTPN6, MAPK14, NCF4 | More | | | Methylprednisolone | hsa05143 | African trypanosomiasis | 1.31E-02 | 2 | P69905, P68871 | HBA2, HBB | More | | | Methylprednisolone | hsa05144 | Malaria | 9.96E-05 | 7 | P60033, P69905, P68871, O60603, P01375, P35443, P26718 | CD81, HBA2, HBB, TLR2, TNF, THBS4, KLRK1 | More | | | Methylprednisolone | hsa05145 | Toxoplasmosis | 1.11E-02 | 6 | P10415, Q13489, P42224, P13765, O60603, P29965 | BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LG | More | | | Methylprednisolone | hsa05146 | Amoebiasis | 5.94E-04 | 9 | P09341, P14778, P27930, P01375, O60603, P05089, P22694, P12814, P08311 | CXCL1, IL1R1, IL1R2, TNF, TLR2, ARG1, PRKACB, ACTN1, CTSG | More | | | Methylprednisolone | hsa05150 | Staphylococcus aureus infection | 1.02E-03 | 7 | P21730, P21462, O75015, P59665, P59666, P12838, P49913 | C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMP | More | | | Methylprednisolone | hsa05152 | Tuberculosis | 7.93E-04 | 8 | Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8 | TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1 | More | | | Methylprednisolone | hsa05163 | Human cytomegalovirus infection | 2.51E-02 | 9 | P01375, Q14643, P22694, P49841, P14778, Q13651, P25025, Q16539, O00463 | TNF, ITPR1, PRKACB, GSK3B, IL1R1, IL10RA, CXCR2, MAPK14, TRAF5 | More | | | Methylprednisolone | hsa05165 | Human papillomavirus infection | 3.10E-02 | 8 | P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315 | ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATM | More | | | Methylprednisolone | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 4.73E-02 | 6 | P01568, P42224, P62873, Q14643, P0DP23, Q9UJU2 | IFNA21, STAT1, GNB1, ITPR1, CALM1, LEF1 | More | | | Methylprednisolone | hsa05170 | Human immunodeficiency virus 1 infection | 4.67E-03 | 9 | P62873, P0DP23, P17252, Q14643, P01568, O60603, Q13315, P10415, Q9Y6Q5 | GNB1, CALM1, PRKCA, ITPR1, IFNA21, TLR2, ATM, BCL2, AP1M2 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P11511 | CYP19A1 | Aromatase | Q02750 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P11511 | CYP19A1 | Aromatase | P62879 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | 0.704 | | P11511 | CYP19A1 | Aromatase | P16298 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P11511 | CYP19A1 | Aromatase | Q05397 | PTK2 | Focal adhesion kinase 1 | 0.75 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P11511 | CYP19A1 | Aromatase | P20333 | TNFRSF1B | Tumor necrosis factor receptor superfamily member 1B | -0.75 |
| | Methylprednisolone | hsa05200 | Pathways in cancer | 4.99E-02 | 12 | P42224, Q9UJU2, P17252, P14923, P10415, Q13489, P49767, Q12778, P25116, P62873, P0DP23, P01568 | STAT1, LEF1, PRKCA, JUP, BCL2, BIRC3, VEGFC, FOXO1, F2R, GNB1, CALM1, IFNA21 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 |
| | Methylprednisolone | hsa05202 | Transcriptional misregulation in cancer | 4.29E-03 | 13 | P14780, P27930, Q15744, Q16548, P11215, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, P12980, P24522 | MMP9, IL1R2, CEBPE, BCL2A1, ITGAM, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, LYL1, GADD45A | More | | | Methylprednisolone | hsa05203 | Viral carcinogenesis | 1.22E-03 | 6 | Q13547, Q15283, P58876, P62807, Q16778, O60814 | HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12 | More | | | Methylprednisolone | hsa05204 | Chemical carcinogenesis | 1.48E-02 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Methylprednisolone | hsa05230 | Central carbon metabolism in cancer | 1.12E-02 | 1 | P11413 | G6PD | More | | | Methylprednisolone | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 1.42E-02 | 7 | O95267, P20963, P09693, P06239, O60603, Q04759, Q16539 | RASGRP1, CD247, CD3G, LCK, TLR2, PRKCQ, MAPK14 | More | | | Methylprednisolone | hsa05310 | Asthma | 1.62E-02 | 3 | P13765, P12724, P01375 | HLA-DOB, RNASE3, TNF | More | | | Methylprednisolone | hsa05320 | Autoimmune thyroid disease | 1.27E-03 | 4 | P13765, P29965, P01568, P10747 | HLA-DOB, CD40LG, IFNA21, CD28 | More | | | Methylprednisolone | hsa05321 | Inflammatory bowel disease | 1.09E-03 | 6 | O60603, P01375, P13765, Q14765, Q9UL17, P23771 | TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3 | More | | | Methylprednisolone | hsa05322 | Systemic lupus erythematosus | 2.33E-07 | 12 | P08246, P09871, P10747, P13765, P29965, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431 | ELA2, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 |
| | Methylprednisolone | hsa05323 | Rheumatoid arthritis | 1.29E-02 | 4 | P13765, Q13488, P10747, O60603 | HLA-DOB, TCIRG1, CD28, TLR2 | More | | | Methylprednisolone | hsa05330 | Allograft rejection | 1.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | | | Methylprednisolone | hsa05332 | Graft-versus-host disease | 1.76E-02 | 4 | P13765, P01375, P26715, Q13241 | HLA-DOB, TNF, KLRC1, KLRD1 | More | | | Methylprednisolone | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.93E-02 | 1 | P54284 | CACNB3 | More | | | Methylprednisolone | hsa05415 | Diabetic cardiomyopathy | 2.33E-02 | 6 | P17252, P14598, Q15080, Q16718, O14521, P11413 | PRKCA, NCF1, NCF4, NDUFA5, SDHD, G6PD | More | | | Methylprednisolone | hsa05416 | Viral myocarditis | 2.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | | | Prednisolone-acetate | hsa00030 | Pentose phosphate pathway | 8.97E-03 | 1 | P11413 | G6PD | More | | | Prednisolone-acetate | hsa00052 | Galactose metabolism | 1.03E-02 | 2 | P06280, O43451 | GLA, MGAM | More | | | Prednisolone-acetate | hsa00053 | Ascorbate and aldarate metabolism | 4.93E-02 | 1 | P14550 | AKR1A1 | More | | | Prednisolone-acetate | hsa00190 | Oxidative phosphorylation | 8.71E-03 | 3 | Q16718, Q13488, O14521 | NDUFA5, TCIRG1, SDHD | More | | | Prednisolone-acetate | hsa00480 | Glutathione metabolism | 1.35E-02 | 1 | P11413 | G6PD | More | | | Prednisolone-acetate | hsa00500 | Starch and sucrose metabolism | 1.67E-02 | 2 | O43451, P06737 | MGAM, PYGL | More | | | Prednisolone-acetate | hsa00565 | Ether lipid metabolism | 4.93E-02 | 1 | Q8N661 | TMEM86B | More | | | Prednisolone-acetate | hsa00590 | Arachidonic acid metabolism | 3.85E-02 | 2 | P11712, P09960 | CYP2C9, LTA4H | More | | | Prednisolone-acetate | hsa00591 | Linoleic acid metabolism | 4.07E-02 | 1 | P11712 | CYP2C9 | More | | | Prednisolone-acetate | hsa00730 | Thiamine metabolism | 5.29E-03 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Prednisolone-acetate | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 9.14E-03 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Prednisolone-acetate | hsa00982 | Drug metabolism - cytochrome P450 | 9.14E-03 | 2 | P11712, P78417 | CYP2C9, GSTO1 | More | | | Prednisolone-acetate | hsa00983 | Drug metabolism - other enzymes | 2.44E-02 | 2 | P32320, P05164 | CDA, MPO | More | | | Prednisolone-acetate | hsa01200 | Carbon metabolism | 2.91E-02 | 1 | P11413 | G6PD | More | | | Prednisolone-acetate | hsa02010 | ABC transporters | 4.93E-02 | 1 | Q8IZY2 | ABCA7 | More | | | Prednisolone-acetate | hsa03013 | RNA transport | 8.19E-04 | 7 | Q15287, Q9UBU9, P35658, P63279, P55884, O15371, P20042 | RNPS1, NXF1, NUP214, UBE2I, EIF3B, EIF3D, EIF2S2 | More | | | Prednisolone-acetate | hsa03040 | Spliceosome | 3.98E-02 | 4 | Q15427, P38159, P61978, P11142 | SF3B4, RBMX, HNRPK, HSPA8 | More | | | Prednisolone-acetate | hsa03060 | Protein export | 9.07E-04 | 2 | P37108, Q15005 | SRP14, SPCS2 | More | | | Prednisolone-acetate | hsa04012 | ErbB signaling pathway | 3.74E-02 | 3 | P21860, Q13557, O14944 | ERBB3, CAMK2D, EREG | More | | | Prednisolone-acetate | hsa04020 | Calcium signaling pathway | 2.19E-05 | 10 | Q96DU7, Q08828, P45880, Q13557, P21860, P61073, P0DP24, P05141, P51828, P23634 | ITPKC, ADCY1, VDAC2, CAMK2D, ERBB3, CXCR4, CALM2, SLC25A5, ADCY7, ATP2B4 | More | | | Prednisolone-acetate | hsa04022 | cGMP-PKG signaling pathway | 2.45E-03 | 8 | Q99941, P18848, P23634, Q08828, P51828, P05141, P45880, P0DP24 | CREBL1, ATF4, ATP2B4, ADCY1, ADCY7, SLC25A5, VDAC2, CALM2 | More | | | Prednisolone-acetate | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 1.91E-02 | 3 | Q8NHW4, P61073, Q13651 | CCL4L2, CXCR4, IL10RA | More | | | Prednisolone-acetate | hsa04064 | NF-kappa B signaling pathway | 1.25E-04 | 12 | P10415, Q13489, Q13546, P01584, P29965, Q9UDY8, Q8WV28, Q13315, P63279, Q8NHW4, Q9UNE0, Q9NQC7 | BCL2, BIRC3, RIPK1, IL1B, CD40LG, MALT1, BLNK, ATM, UBE2I, CCL4L2, EDAR, CYLD | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P01584 | IL1B | Interleukin-1 beta | P63279 | UBE2I | SUMO-conjugating enzyme UBC9 | 0.815 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 |
| | Prednisolone-acetate | hsa04070 | Phosphatidylinositol signaling system | 3.47E-02 | 4 | P0DP23, Q14643, P23743, P17252 | CALM1, ITPR1, DGKA, PRKCA | More | | | Prednisolone-acetate | hsa04071 | Sphingolipid signaling pathway | 2.87E-03 | 7 | P17252, Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2 | PRKCA, EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2 | More | | | Prednisolone-acetate | hsa04114 | Oocyte meiosis | 4.36E-02 | 5 | Q13557, P0DP24, Q08828, P51828, P27348 | CAMK2D, CALM2, ADCY1, ADCY7, YWHAQ | More | | | Prednisolone-acetate | hsa04141 | Protein processing in endoplasmic reticulum | 3.64E-02 | 5 | Q99941, O75460, P11142, Q9H3Z4, P07900 | CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1 | More | | | Prednisolone-acetate | hsa04145 | Phagosome | 1.59E-03 | 7 | Q15080, P14598, Q13509, P68371, Q13488, O60603, P13765 | NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, TLR2, HLA-DOB | More | | | Prednisolone-acetate | hsa04151 | PI3K-Akt signaling pathway | 4.50E-02 | 9 | P25116, P49767, Q13362, P62873, P16144, O60603, P01568, P10415, P17252 | F2R, VEGFC, PPP2R5C, GNB1, ITGB4, TLR2, IFNA21, BCL2, PRKCA | More | | | Prednisolone-acetate | hsa04210 | Apoptosis | 3.58E-02 | 4 | O76075, P01375, Q9NR28, Q16548 | DFFB, TNF, DIABLO, BCL2A1 | More | | | Prednisolone-acetate | hsa04211 | Longevity regulating pathway | 3.41E-03 | 7 | Q12778, Q08828, P51828, Q99941, P18848, Q9UEF7, Q96KQ7 | FOXO1, ADCY1, ADCY7, CREBL1, ATF4, KL, EHMT2 | More | | | Prednisolone-acetate | hsa04213 | Longevity regulating pathway - multiple species | 2.85E-02 | 2 | Q9Y4H2, Q13547 | IRS2, HDAC1 | More | | | Prednisolone-acetate | hsa04217 | Necroptosis | 2.08E-05 | 15 | P01568, P23458, Q13489, Q9NQC7, Q13546, P42224, P05141, P01584, P0C0S5, Q6FI13, P10415, Q13557, Q9H444, O43633, Q08752 | IFNA21, JAK1, BIRC3, CYLD, RIPK1, STAT1, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, BCL2, CAMK2D, CHMP4B, CHMP2A, PPID | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P01584 | IL1B | Interleukin-1 beta | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | 0.799 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P01584 | IL1B | Interleukin-1 beta | P0C0S5 | H2AFZ | Histone H2A.Z | 0.762 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | Q9H444 | CHMP4B | Charged multivesicular body protein 4b | 0.716 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone-acetate | hsa04261 | Adrenergic signaling in cardiomyocytes | 1.49E-04 | 12 | P09493, Q08828, P51828, Q99941, P18848, Q13362, P0DP23, P0DP24, Q13557, P17252, P10415, P23634 | TPM1, ADCY1, ADCY7, CREBL1, ATF4, PPP2R5C, CALM1, CALM2, CAMK2D, PRKCA, BCL2, ATP2B4 | More | | | Prednisolone-acetate | hsa04330 | Notch signaling pathway | 4.34E-02 | 2 | Q92542, P46531 | NCSTN, NOTCH1 | More | | | Prednisolone-acetate | hsa04340 | Hedgehog signaling pathway | 3.32E-02 | 2 | P49841, P22694 | GSK3B, PRKACB | More | | | Prednisolone-acetate | hsa04380 | Osteoclast differentiation | 4.98E-02 | 4 | Q9NQC7, Q9UQC2, P23458, P01584 | CYLD, GAB2, JAK1, IL1B | More | | | Prednisolone-acetate | hsa04530 | Tight junction | 3.29E-02 | 3 | P16989, P56750, Q14247 | CSDA, CLDN17, CTTN | More | | | Prednisolone-acetate | hsa04540 | Gap junction | 1.29E-02 | 4 | P17252, Q13509, P68371, Q14643 | PRKCA, TUBB3, TUBB2C, ITPR1 | More | | | Prednisolone-acetate | hsa04610 | Complement and coagulation cascades | 2.33E-03 | 1 | P0C0L4 | C4A | More | | | Prednisolone-acetate | hsa04612 | Antigen processing and presentation | 4.78E-02 | 6 | P48382, P26715, P26717, Q13241, O43908, P01375 | RFX5, KLRC1, KLRC2, KLRD1, KLRC4, TNF | More | | | Prednisolone-acetate | hsa04613 | Neutrophil extracellular trap formation | 4.29E-05 | 15 | P17252, P11215, O60603, P08246, Q13547, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, P14598, Q15080, P21462 | PRKCA, ITGAM, TLR2, ELA2, HDAC1, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 |
| | Prednisolone-acetate | hsa04620 | Toll-like receptor signaling pathway | 4.16E-02 | 2 | Q13546, P01568 | RIPK1, IFNA21 | More | | | Prednisolone-acetate | hsa04621 | NOD-like receptor signaling pathway | 4.48E-03 | 12 | P01568, Q13489, Q9H1Y0, P43490, O00463, Q13546, Q05823, P01375, P49913, P59665, P59666, P12838 | IFNA21, BIRC3, ATG5, PBEF1, TRAF5, RIPK1, RNASEL, TNF, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 |
| | Prednisolone-acetate | hsa04622 | RIG-I-like receptor signaling pathway | 2.39E-02 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Prednisolone-acetate | hsa04623 | Cytosolic DNA-sensing pathway | 5.86E-05 | 4 | P01584, P01568, Q13546, Q8NHW4 | IL1B, IFNA21, RIPK1, CCL4L2 | More | | | Prednisolone-acetate | hsa04650 | Natural killer cell mediated cytotoxicity | 1.25E-02 | 8 | P01375, O60880, P20963, Q13241, P26718, O75015, P26717, P26715 | TNF, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P11511 | CYP19A1 | Aromatase | P16298 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 0.706 | | P11511 | CYP19A1 | Aromatase | P50591 | TNFSF10 | Tumor necrosis factor ligand superfamily member 10 | 0.701 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P11511 | CYP19A1 | Aromatase | Q02750 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | 0.783 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 |
| | Prednisolone-acetate | hsa04657 | IL-17 signaling pathway | 3.31E-02 | 3 | P49841, P14780, P01375 | GSK3B, MMP9, TNF | More | | | Prednisolone-acetate | hsa04668 | TNF signaling pathway | 4.74E-02 | 3 | Q99941, P01584, O95429 | CREBL1, IL1B, BAG4 | More | | | Prednisolone-acetate | hsa04672 | Intestinal immune network for IgA production | 3.76E-03 | 3 | P29965, P10747, P13765 | CD40LG, CD28, HLA-DOB | More | | | Prednisolone-acetate | hsa04713 | Circadian entrainment | 1.25E-03 | 8 | P0DP23, P0DP24, Q13557, P17252, P62873, Q14643, Q08828, P51828 | CALM1, CALM2, CAMK2D, PRKCA, GNB1, ITPR1, ADCY1, ADCY7 | More | | | Prednisolone-acetate | hsa04720 | Long-term potentiation | 1.63E-03 | 7 | P17252, Q13557, P0DP23, P0DP24, P18848, Q08828, Q14643 | PRKCA, CAMK2D, CALM1, CALM2, ATF4, ADCY1, ITPR1 | More | | | Prednisolone-acetate | hsa04722 | Neurotrophin signaling pathway | 9.39E-03 | 2 | Q05655, P52566 | PRKCD, ARHGDIB | More | | | Prednisolone-acetate | hsa04723 | Retrograde endocannabinoid signaling | 1.88E-02 | 4 | Q14643, P17252, P62873, Q16718 | ITPR1, PRKCA, GNB1, NDUFA5 | More | | | Prednisolone-acetate | hsa04725 | Cholinergic synapse | 1.75E-03 | 8 | Q08828, P51828, Q14643, P17252, P62873, P18848, Q13557, P10415 | ADCY1, ADCY7, ITPR1, PRKCA, GNB1, ATF4, CAMK2D, BCL2 | More | | | Prednisolone-acetate | hsa04728 | Dopaminergic synapse | 2.57E-03 | 10 | Q14643, P17252, P62873, Q99941, P18848, Q13557, Q13362, P0DP23, P0DP24, O15516 | ITPR1, PRKCA, GNB1, CREBL1, ATF4, CAMK2D, PPP2R5C, CALM1, CALM2, CLOCK | More | | | Prednisolone-acetate | hsa04744 | Phototransduction | 1.02E-02 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | | | Prednisolone-acetate | hsa04750 | Inflammatory mediator regulation of TRP channels | 4.53E-04 | 5 | P01584, Q08828, P51828, Q13557, P0DP24 | IL1B, ADCY1, ADCY7, CAMK2D, CALM2 | More | | | Prednisolone-acetate | hsa04910 | Insulin signaling pathway | 2.35E-02 | 3 | P22694, P06737, P49841 | PRKACB, PYGL, GSK3B | More | | | Prednisolone-acetate | hsa04911 | Insulin secretion | 2.95E-05 | 5 | Q08828, P51828, Q99941, P18848, Q13557 | ADCY1, ADCY7, CREBL1, ATF4, CAMK2D | More | | | Prednisolone-acetate | hsa04912 | GnRH signaling pathway | 5.97E-04 | 8 | P17252, Q08828, P51828, P18848, Q13557, Q14643, P0DP23, P0DP24 | PRKCA, ADCY1, ADCY7, ATF4, CAMK2D, ITPR1, CALM1, CALM2 | More | | | Prednisolone-acetate | hsa04915 | Estrogen signaling pathway | 4.72E-02 | 4 | Q99941, P51828, P07900, P11142 | CREBL1, ADCY7, HSP90AA1, HSPA8 | More | | | Prednisolone-acetate | hsa04916 | Melanogenesis | 7.61E-03 | 4 | Q13557, P0DP24, Q08828, P51828 | CAMK2D, CALM2, ADCY1, ADCY7 | More | | | Prednisolone-acetate | hsa04918 | Thyroid hormone synthesis | 4.47E-03 | 5 | Q08828, P51828, Q99941, P18848, P02768 | ADCY1, ADCY7, CREBL1, ATF4, ALB | More | | | Prednisolone-acetate | hsa04919 | Thyroid hormone signaling pathway | 7.11E-03 | 4 | P49841, P22694, O60244, Q9NVC6 | GSK3B, PRKACB, MED14, MED17 | More | | | Prednisolone-acetate | hsa04922 | Glucagon signaling pathway | 3.47E-02 | 4 | Q12778, Q13370, P0DP23, Q14643 | FOXO1, PDE3B, CALM1, ITPR1 | More | | | Prednisolone-acetate | hsa04924 | Renin secretion | 8.71E-03 | 3 | Q14643, Q13370, P0DP23 | ITPR1, PDE3B, CALM1 | More | | | Prednisolone-acetate | hsa04925 | Aldosterone synthesis and secretion | 8.00E-06 | 7 | Q99941, P18848, Q08828, P51828, P0DP24, Q13557, P23634 | CREBL1, ATF4, ADCY1, ADCY7, CALM2, CAMK2D, ATP2B4 | More | | | Prednisolone-acetate | hsa04927 | Cortisol synthesis and secretion | 4.16E-03 | 4 | Q99941, P18848, Q08828, P51828 | CREBL1, ATF4, ADCY1, ADCY7 | More | | | Prednisolone-acetate | hsa04928 | Parathyroid hormone synthesis, secretion and action | 3.77E-02 | 4 | Q08828, P51828, Q99941, P18848 | ADCY1, ADCY7, CREBL1, ATF4 | More | | | Prednisolone-acetate | hsa04930 | Type II diabetes mellitus | 2.68E-02 | 1 | Q05655 | PRKCD | More | | | Prednisolone-acetate | hsa04931 | Insulin resistance | 1.94E-02 | 3 | P01375, P49841, P06737 | TNF, GSK3B, PYGL | More | | | Prednisolone-acetate | hsa04932 | Non-alcoholic fatty liver disease | 3.45E-02 | 5 | P18848, O75460, P01584, P12074, O15239 | ATF4, ERN1, IL1B, COX6A1, NDUFA1 | More | | | Prednisolone-acetate | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 1.27E-02 | 5 | P42224, P10415, Q12778, P49767, P17252 | STAT1, BCL2, FOXO1, VEGFC, PRKCA | More | | | Prednisolone-acetate | hsa04934 | Cushing syndrome | 2.69E-06 | 6 | Q99941, P18848, Q08828, P51828, O15169, Q13557 | CREBL1, ATF4, ADCY1, ADCY7, AXIN1, CAMK2D | More | | | Prednisolone-acetate | hsa04935 | Growth hormone synthesis, secretion and action | 4.98E-02 | 4 | Q08828, P51828, Q99941, P18848 | ADCY1, ADCY7, CREBL1, ATF4 | More | | | Prednisolone-acetate | hsa04964 | Proximal tubule bicarbonate reclamation | 4.93E-02 | 1 | P00918 | CA2 | More | | | Prednisolone-acetate | hsa04966 | Collecting duct acid secretion | 2.07E-03 | 3 | Q13488, P00918, Q9Y666 | TCIRG1, CA2, SLC12A7 | More | | | Prednisolone-acetate | hsa04970 | Salivary secretion | 3.54E-02 | 3 | Q08828, P51828, P0DP24 | ADCY1, ADCY7, CALM2 | More | | | Prednisolone-acetate | hsa04971 | Gastric acid secretion | 2.95E-05 | 5 | Q08828, P51828, P15311, P0DP24, Q13557 | ADCY1, ADCY7, VIL2, CALM2, CAMK2D | More | | | Prednisolone-acetate | hsa04975 | Fat digestion and absorption | 2.80E-02 | 1 | O14494 | PLPP1 | More | | | Prednisolone-acetate | hsa04976 | Bile secretion | 2.44E-02 | 2 | P22694, P08183 | PRKACB, ABCB1 | More | | | Prednisolone-acetate | hsa05010 | Alzheimer disease | 3.93E-05 | 21 | Q92542, O15239, Q16718, O14521, P05496, P12074, Q14643, Q00535, O75460, P0DP23, P0DP24, P01584, P18848, Q13509, P68371, O15169, P05141, P45880, Q08752, P28070, P43686 | NCSTN, NDUFA1, NDUFA5, SDHD, ATP5G1, COX6A1, ITPR1, CDK5, ERN1, CALM1, CALM2, IL1B, ATF4, TUBB3, TUBB2C, AXIN1, SLC25A5, VDAC2, PPID, PSMB4, PSMC4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q92542 | NCSTN | Nicastrin | 0.706 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P05496 | ATP5G1 | ATP synthase F(0) complex subunit C1, mitochondrial | 0.733 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.754 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P01584 | IL1B | Interleukin-1 beta | 0.75 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O15169 | AXIN1 | Axin-1 | 0.742 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P45880 | VDAC2 | Voltage-dependent anion-selective channel protein 2 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone-acetate | hsa05012 | Parkinson disease | 4.70E-04 | 15 | O15239, Q16718, O14521, P12074, P05141, O75460, P18848, P28070, P43686, Q14643, P0DP23, P0DP24, Q13557, Q13509, P68371 | NDUFA1, NDUFA5, SDHD, COX6A1, SLC25A5, ERN1, ATF4, PSMB4, PSMC4, ITPR1, CALM1, CALM2, CAMK2D, TUBB3, TUBB2C | More | | | Prednisolone-acetate | hsa05016 | Huntington disease | 3.54E-02 | 8 | O15239, P12074, P24928, P62487, P05141, O75460, P28070, P43686 | NDUFA1, COX6A1, POLR2A, POLR2G, SLC25A5, ERN1, PSMB4, PSMC4 | More | | | Prednisolone-acetate | hsa05020 | Prion disease | 9.80E-05 | 19 | P01584, P46531, P11142, O15239, Q16718, O14521, P05496, P12074, Q14643, P18848, P05141, P45880, P28070, P43686, Q13509, P68371, Q99941, P14598, Q15080 | IL1B, NOTCH1, HSPA8, NDUFA1, NDUFA5, SDHD, ATP5G1, COX6A1, ITPR1, ATF4, SLC25A5, VDAC2, PSMB4, PSMC4, TUBB3, TUBB2C, CREBL1, NCF1, NCF4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P01584 | IL1B | Interleukin-1 beta | 0.75 | | P01584 | IL1B | Interleukin-1 beta | P46531 | NOTCH1 | Neurogenic locus notch homolog protein 1 | 0.827 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P46531 | NOTCH1 | Neurogenic locus notch homolog protein 1 | 0.706 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P11142 | HSPA8 | Heat shock cognate 71 kDa protein | 0.766 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P05496 | ATP5G1 | ATP synthase F(0) complex subunit C1, mitochondrial | 0.733 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.754 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P45880 | VDAC2 | Voltage-dependent anion-selective channel protein 2 | 0.708 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P01584 | IL1B | Interleukin-1 beta | Q99941 | CREBL1 | Cyclic AMP-dependent transcription factor ATF-6 beta | 0.704 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q99941 | CREBL1 | Cyclic AMP-dependent transcription factor ATF-6 beta | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 |
| | Prednisolone-acetate | hsa05022 | Pathways of neurodegeneration - multiple diseases | 2.41E-05 | 23 | Q14643, Q13509, P68371, P10415, O15239, Q16718, O14521, P12074, Q8TEV9, O75460, P18848, Q13561, P05141, P17252, Q00535, O15169, P01584, Q08752, P0DP23, P0DP24, Q13557, P28070, P43686 | ITPR1, TUBB3, TUBB2C, BCL2, NDUFA1, NDUFA5, SDHD, COX6A1, SMCR8, ERN1, ATF4, DCTN2, SLC25A5, PRKCA, CDK5, AXIN1, IL1B, PPID, CALM1, CALM2, CAMK2D, PSMB4, PSMC4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P01584 | IL1B | Interleukin-1 beta | Q8TEV9 | SMCR8 | Guanine nucleotide exchange protein SMCR8 | 0.705 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 |
| | Prednisolone-acetate | hsa05030 | Cocaine addiction | 3.54E-02 | 3 | Q00535, Q99941, P18848 | CDK5, CREBL1, ATF4 | More | | | Prednisolone-acetate | hsa05031 | Amphetamine addiction | 7.61E-03 | 4 | P0DP24, Q13557, Q99941, P18848 | CALM2, CAMK2D, CREBL1, ATF4 | More | | | Prednisolone-acetate | hsa05034 | Alcoholism | 2.05E-05 | 7 | Q13547, Q93077, P58876, P62807, Q16778, O60814, P68431 | HDAC1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | | Prednisolone-acetate | hsa05131 | Shigellosis | 3.99E-03 | 10 | P68431, Q05655, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752, P07737 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, PRKCD, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID, PFN1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | Q05655 | PRKCD | Protein kinase C delta type | Q05655 | PRKCD | Protein kinase C delta type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | Q05655 | PRKCD | Protein kinase C delta type | P07737 | PFN1 | Profilin-1 | 0.77 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone-acetate | hsa05132 | Salmonella infection | 2.53E-04 | 12 | Q9UJU2, P84095, Q13546, Q13489, P10415, P07737, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371 | LEF1, RHOG, RIPK1, BIRC3, BCL2, PFN1, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2C | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | Q05655 | PRKCD | Protein kinase C delta type | P84095 | RHOG | Rho-related GTP-binding protein RhoG | 0.71 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | Q05655 | PRKCD | Protein kinase C delta type | P07737 | PFN1 | Profilin-1 | 0.77 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 |
| | Prednisolone-acetate | hsa05133 | Pertussis | 4.20E-02 | 1 | P0C0L4 | C4A | More | | | Prednisolone-acetate | hsa05140 | Leishmaniasis | 2.17E-03 | 6 | P14598, P42224, P13765, O60603, P29350, Q15080 | NCF1, STAT1, HLA-DOB, TLR2, PTPN6, NCF4 | More | | | Prednisolone-acetate | hsa05143 | African trypanosomiasis | 1.31E-02 | 2 | P69905, P68871 | HBA2, HBB | More | | | Prednisolone-acetate | hsa05144 | Malaria | 3.76E-03 | 6 | P60033, P69905, P68871, P01375, P35443, P26718 | CD81, HBA2, HBB, TNF, THBS4, KLRK1 | More | | | Prednisolone-acetate | hsa05145 | Toxoplasmosis | 1.11E-02 | 6 | P10415, Q13489, P42224, P13765, O60603, P29965 | BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LG | More | | | Prednisolone-acetate | hsa05150 | Staphylococcus aureus infection | 1.02E-03 | 7 | P21730, P21462, O75015, P59665, P59666, P12838, P49913 | C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMP | More | | | Prednisolone-acetate | hsa05152 | Tuberculosis | 7.93E-04 | 8 | Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8 | TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1 | More | | | Prednisolone-acetate | hsa05163 | Human cytomegalovirus infection | 2.62E-04 | 10 | P0DP24, Q8NHW4, Q08828, P51828, P23458, P01584, P61073, Q13651, Q99941, P18848 | CALM2, CCL4L2, ADCY1, ADCY7, JAK1, IL1B, CXCR4, IL10RA, CREBL1, ATF4 | More | | | Prednisolone-acetate | hsa05165 | Human papillomavirus infection | 3.10E-02 | 8 | P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315 | ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATM | More | | | Prednisolone-acetate | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 4.73E-02 | 6 | P01568, P42224, P62873, Q14643, P0DP23, Q9UJU2 | IFNA21, STAT1, GNB1, ITPR1, CALM1, LEF1 | More | | | Prednisolone-acetate | hsa05170 | Human immunodeficiency virus 1 infection | 4.67E-03 | 9 | P62873, P0DP23, P17252, Q14643, P01568, O60603, Q13315, P10415, Q9Y6Q5 | GNB1, CALM1, PRKCA, ITPR1, IFNA21, TLR2, ATM, BCL2, AP1M2 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P11511 | CYP19A1 | Aromatase | Q02750 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P11511 | CYP19A1 | Aromatase | P62879 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | 0.704 | | P11511 | CYP19A1 | Aromatase | P16298 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P11511 | CYP19A1 | Aromatase | Q05397 | PTK2 | Focal adhesion kinase 1 | 0.75 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P11511 | CYP19A1 | Aromatase | P20333 | TNFRSF1B | Tumor necrosis factor receptor superfamily member 1B | -0.75 |
| | Prednisolone-acetate | hsa05200 | Pathways in cancer | 4.99E-02 | 12 | P42224, Q9UJU2, P17252, P14923, P10415, Q13489, P49767, Q12778, P25116, P62873, P0DP23, P01568 | STAT1, LEF1, PRKCA, JUP, BCL2, BIRC3, VEGFC, FOXO1, F2R, GNB1, CALM1, IFNA21 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 |
| | Prednisolone-acetate | hsa05202 | Transcriptional misregulation in cancer | 1.24E-02 | 4 | P27930, P11215, Q13547, P12980 | IL1R2, ITGAM, HDAC1, LYL1 | More | | | Prednisolone-acetate | hsa05203 | Viral carcinogenesis | 1.22E-03 | 6 | Q13547, Q15283, P58876, P62807, Q16778, O60814 | HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12 | More | | | Prednisolone-acetate | hsa05204 | Chemical carcinogenesis | 1.48E-02 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Prednisolone-acetate | hsa05206 | MicroRNAs in cancer | 2.97E-03 | 6 | P15311, P21860, P61978, P46531, P63279, P22105 | VIL2, ERBB3, HNRPK, NOTCH1, UBE2I, TNXB | More | | | Prednisolone-acetate | hsa05230 | Central carbon metabolism in cancer | 1.12E-02 | 1 | P11413 | G6PD | More | | | Prednisolone-acetate | hsa05320 | Autoimmune thyroid disease | 1.27E-03 | 4 | P13765, P29965, P01568, P10747 | HLA-DOB, CD40LG, IFNA21, CD28 | More | | | Prednisolone-acetate | hsa05322 | Systemic lupus erythematosus | 2.33E-07 | 12 | P08246, P09871, P10747, P13765, P29965, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431 | ELA2, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 |
| | Prednisolone-acetate | hsa05323 | Rheumatoid arthritis | 1.29E-02 | 4 | P13765, Q13488, P10747, O60603 | HLA-DOB, TCIRG1, CD28, TLR2 | More | | | Prednisolone-acetate | hsa05330 | Allograft rejection | 1.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | | | Prednisolone-acetate | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.93E-02 | 1 | P54284 | CACNB3 | More | | | Prednisolone-acetate | hsa05415 | Diabetic cardiomyopathy | 2.33E-02 | 6 | P17252, P14598, Q15080, Q16718, O14521, P11413 | PRKCA, NCF1, NCF4, NDUFA5, SDHD, G6PD | More | | | Prednisolone-acetate | hsa05416 | Viral myocarditis | 2.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | | | Prednisolone-phosphate | hsa00030 | Pentose phosphate pathway | 8.97E-03 | 1 | P11413 | G6PD | More | | | Prednisolone-phosphate | hsa00052 | Galactose metabolism | 1.03E-02 | 2 | P06280, O43451 | GLA, MGAM | More | | | Prednisolone-phosphate | hsa00053 | Ascorbate and aldarate metabolism | 4.93E-02 | 1 | P14550 | AKR1A1 | More | | | Prednisolone-phosphate | hsa00480 | Glutathione metabolism | 1.35E-02 | 1 | P11413 | G6PD | More | | | Prednisolone-phosphate | hsa00500 | Starch and sucrose metabolism | 2.00E-03 | 3 | O43451, P46976, P06737 | MGAM, GYG1, PYGL | More | | | Prednisolone-phosphate | hsa00565 | Ether lipid metabolism | 4.93E-02 | 1 | Q8N661 | TMEM86B | More | | | Prednisolone-phosphate | hsa00730 | Thiamine metabolism | 5.29E-03 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Prednisolone-phosphate | hsa00970 | Aminoacyl-tRNA biosynthesis | 1.21E-02 | 1 | P14868 | DARS | More | | | Prednisolone-phosphate | hsa00983 | Drug metabolism - other enzymes | 2.44E-02 | 2 | P32320, P05164 | CDA, MPO | More | | | Prednisolone-phosphate | hsa01200 | Carbon metabolism | 2.91E-02 | 1 | P11413 | G6PD | More | | | Prednisolone-phosphate | hsa02010 | ABC transporters | 4.93E-02 | 1 | Q8IZY2 | ABCA7 | More | | | Prednisolone-phosphate | hsa03013 | RNA transport | 3.11E-02 | 2 | P68104, Q14232 | EEF1A1, EIF2B1 | More | | | Prednisolone-phosphate | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 2.00E-02 | 7 | P09341, P25024, P25025, P47992, Q9UBD3, Q13651, P01375 | CXCL1, CXCR1, CXCR2, XCL1, XCL2, IL10RA, TNF | More | | | Prednisolone-phosphate | hsa04064 | NF-kappa B signaling pathway | 4.58E-03 | 4 | Q13489, Q13546, Q9UDY8, Q9UNE0 | BIRC3, RIPK1, MALT1, EDAR | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P01584 | IL1B | Interleukin-1 beta | P63279 | UBE2I | SUMO-conjugating enzyme UBC9 | 0.815 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 |
| | Prednisolone-phosphate | hsa04071 | Sphingolipid signaling pathway | 1.94E-02 | 3 | Q9H228, P01375, Q9UQC2 | EDG8, TNF, GAB2 | More | | | Prednisolone-phosphate | hsa04140 | Autophagy - animal | 3.61E-02 | 5 | Q9NQL2, P22694, Q14643, Q9H1Y0, Q04759 | RRAGD, PRKACB, ITPR1, ATG5, PRKCQ | More | | | Prednisolone-phosphate | hsa04141 | Protein processing in endoplasmic reticulum | 3.89E-02 | 2 | P17861, Q9NR31 | XBP1, SAR1A | More | | | Prednisolone-phosphate | hsa04210 | Apoptosis | 3.58E-02 | 4 | O76075, P01375, Q9NR28, Q16548 | DFFB, TNF, DIABLO, BCL2A1 | More | | | Prednisolone-phosphate | hsa04211 | Longevity regulating pathway | 1.18E-02 | 3 | Q12778, Q9UEF7, Q96KQ7 | FOXO1, KL, EHMT2 | More | | | Prednisolone-phosphate | hsa04217 | Necroptosis | 2.93E-02 | 3 | P01568, Q13489, Q13546 | IFNA21, BIRC3, RIPK1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P01584 | IL1B | Interleukin-1 beta | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | 0.799 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P01584 | IL1B | Interleukin-1 beta | P0C0S5 | H2AFZ | Histone H2A.Z | 0.762 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | Q9H444 | CHMP4B | Charged multivesicular body protein 4b | 0.716 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone-phosphate | hsa04340 | Hedgehog signaling pathway | 3.32E-02 | 2 | P49841, P22694 | GSK3B, PRKACB | More | | | Prednisolone-phosphate | hsa04610 | Complement and coagulation cascades | 2.33E-03 | 1 | P0C0L4 | C4A | More | | | Prednisolone-phosphate | hsa04612 | Antigen processing and presentation | 3.60E-03 | 8 | P13765, P48382, P26715, P26717, Q13241, O43908, P01732, P01375 | HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNF | More | | | Prednisolone-phosphate | hsa04613 | Neutrophil extracellular trap formation | 1.96E-02 | 12 | O60603, P05164, P08246, Q9UM07, Q13547, Q16778, P20160, P08311, O75015, P21730, O43315, Q16539 | TLR2, MPO, ELA2, PADI4, HDAC1, HIST2H2BE, AZU1, CTSG, FCGR3B, C5AR1, AQP9, MAPK14 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 |
| | Prednisolone-phosphate | hsa04620 | Toll-like receptor signaling pathway | 4.16E-02 | 2 | Q13546, P01568 | RIPK1, IFNA21 | More | | | Prednisolone-phosphate | hsa04621 | NOD-like receptor signaling pathway | 3.13E-04 | 17 | Q16539, Q14643, P01568, Q13489, P10599, Q9H1Y0, P43490, O00463, Q13546, P29728, Q05823, P01375, P09341, P49913, P59665, P59666, P12838 | MAPK14, ITPR1, IFNA21, BIRC3, TXN, ATG5, PBEF1, TRAF5, RIPK1, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 |
| | Prednisolone-phosphate | hsa04622 | RIG-I-like receptor signaling pathway | 2.39E-02 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Prednisolone-phosphate | hsa04623 | Cytosolic DNA-sensing pathway | 2.20E-03 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Prednisolone-phosphate | hsa04640 | Hematopoietic cell lineage | 1.10E-02 | 9 | P13612, P14778, P27930, P15144, P25063, P09693, P01732, P13765, P01375 | ITGA4, IL1R1, IL1R2, ANPEP, CD24, CD3G, CD8A, HLA-DOB, TNF | More | | | Prednisolone-phosphate | hsa04650 | Natural killer cell mediated cytotoxicity | 3.11E-04 | 9 | P01375, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, P26715 | TNF, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P11511 | CYP19A1 | Aromatase | P16298 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 0.706 | | P11511 | CYP19A1 | Aromatase | P50591 | TNFSF10 | Tumor necrosis factor ligand superfamily member 10 | 0.701 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P11511 | CYP19A1 | Aromatase | Q02750 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | 0.783 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 |
| | Prednisolone-phosphate | hsa04657 | IL-17 signaling pathway | 1.80E-03 | 7 | O00463, Q16539, P49841, P09341, P14780, P80188, P01375 | TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF | More | | | Prednisolone-phosphate | hsa04658 | Th1 and Th2 cell differentiation | 5.94E-04 | 9 | Q04759, P20963, P09693, Q16539, P06239, Q14765, P23771, Q9UL17, P13765 | PRKCQ, CD247, CD3G, MAPK14, LCK, STAT4, GATA3, TBX21, HLA-DOB | More | | | Prednisolone-phosphate | hsa04659 | Th17 cell differentiation | 3.91E-03 | 9 | Q04759, Q16539, P06239, P13765, P14778, Q9UL17, P23771, P09693, P20963 | PRKCQ, MAPK14, LCK, HLA-DOB, IL1R1, TBX21, GATA3, CD3G, CD247 | More | | | Prednisolone-phosphate | hsa04660 | T cell receptor signaling pathway | 6.95E-04 | 11 | P01375, Q04759, O95267, Q08881, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841 | TNF, PRKCQ, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3B | More | | | Prednisolone-phosphate | hsa04750 | Inflammatory mediator regulation of TRP channels | 3.61E-02 | 5 | P14778, P22694, Q16539, Q14643, Q04759 | IL1R1, PRKACB, MAPK14, ITPR1, PRKCQ | More | | | Prednisolone-phosphate | hsa04910 | Insulin signaling pathway | 2.35E-02 | 3 | P22694, P06737, P49841 | PRKACB, PYGL, GSK3B | More | | | Prednisolone-phosphate | hsa04919 | Thyroid hormone signaling pathway | 7.11E-03 | 4 | P49841, P22694, O60244, Q9NVC6 | GSK3B, PRKACB, MED14, MED17 | More | | | Prednisolone-phosphate | hsa04931 | Insulin resistance | 1.94E-02 | 3 | P01375, P49841, P06737 | TNF, GSK3B, PYGL | More | | | Prednisolone-phosphate | hsa04964 | Proximal tubule bicarbonate reclamation | 4.93E-02 | 1 | P00918 | CA2 | More | | | Prednisolone-phosphate | hsa04966 | Collecting duct acid secretion | 4.93E-02 | 1 | P00918 | CA2 | More | | | Prednisolone-phosphate | hsa04975 | Fat digestion and absorption | 2.80E-02 | 1 | O14494 | PLPP1 | More | | | Prednisolone-phosphate | hsa04976 | Bile secretion | 2.44E-02 | 2 | P22694, P08183 | PRKACB, ABCB1 | More | | | Prednisolone-phosphate | hsa05010 | Alzheimer disease | 1.01E-02 | 3 | Q06055, P17861, P62195 | ATP5G2, XBP1, PSMC5 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q92542 | NCSTN | Nicastrin | 0.706 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P05496 | ATP5G1 | ATP synthase F(0) complex subunit C1, mitochondrial | 0.733 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.754 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P01584 | IL1B | Interleukin-1 beta | 0.75 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O15169 | AXIN1 | Axin-1 | 0.742 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P45880 | VDAC2 | Voltage-dependent anion-selective channel protein 2 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone-phosphate | hsa05012 | Parkinson disease | 5.41E-03 | 3 | Q06055, P17861, P62195 | ATP5G2, XBP1, PSMC5 | More | | | Prednisolone-phosphate | hsa05014 | Amyotrophic lateral sclerosis | 1.01E-02 | 3 | Q06055, P17861, P62195 | ATP5G2, XBP1, PSMC5 | More | | | Prednisolone-phosphate | hsa05017 | Spinocerebellar ataxia | 1.42E-02 | 2 | P17861, P62195 | XBP1, PSMC5 | More | | | Prednisolone-phosphate | hsa05022 | Pathways of neurodegeneration - multiple diseases | 1.66E-02 | 3 | Q06055, P17861, P62195 | ATP5G2, XBP1, PSMC5 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P01584 | IL1B | Interleukin-1 beta | Q8TEV9 | SMCR8 | Guanine nucleotide exchange protein SMCR8 | 0.705 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 |
| | Prednisolone-phosphate | hsa05132 | Salmonella infection | 9.85E-03 | 4 | Q13546, Q13489, O60282, P68371 | RIPK1, BIRC3, KIF5C, TUBB2C | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | Q05655 | PRKCD | Protein kinase C delta type | P84095 | RHOG | Rho-related GTP-binding protein RhoG | 0.71 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | Q05655 | PRKCD | Protein kinase C delta type | P07737 | PFN1 | Profilin-1 | 0.77 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 |
| | Prednisolone-phosphate | hsa05133 | Pertussis | 4.20E-02 | 1 | P0C0L4 | C4A | More | | | Prednisolone-phosphate | hsa05134 | Legionellosis | 5.53E-03 | 2 | Q9NR31, P68104 | SAR1A, EEF1A1 | More | | | Prednisolone-phosphate | hsa05135 | Yersinia infection | 3.72E-02 | 6 | P13612, P06239, Q16539, P01375, P49841, P01732 | ITGA4, LCK, MAPK14, TNF, GSK3B, CD8A | More | | | Prednisolone-phosphate | hsa05140 | Leishmaniasis | 2.69E-02 | 6 | P13612, O75015, P13765, O60603, P01375, Q16539 | ITGA4, FCGR3B, HLA-DOB, TLR2, TNF, MAPK14 | More | | | Prednisolone-phosphate | hsa05143 | African trypanosomiasis | 1.31E-02 | 2 | P69905, P68871 | HBA2, HBB | More | | | Prednisolone-phosphate | hsa05144 | Malaria | 9.96E-05 | 7 | P60033, P69905, P68871, O60603, P01375, P35443, P26718 | CD81, HBA2, HBB, TLR2, TNF, THBS4, KLRK1 | More | | | Prednisolone-phosphate | hsa05146 | Amoebiasis | 5.94E-04 | 9 | P09341, P14778, P27930, P01375, O60603, P05089, P22694, P12814, P08311 | CXCL1, IL1R1, IL1R2, TNF, TLR2, ARG1, PRKACB, ACTN1, CTSG | More | | | Prednisolone-phosphate | hsa05150 | Staphylococcus aureus infection | 1.02E-03 | 7 | P21730, P21462, O75015, P59665, P59666, P12838, P49913 | C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMP | More | | | Prednisolone-phosphate | hsa05163 | Human cytomegalovirus infection | 2.51E-02 | 9 | P01375, Q14643, P22694, P49841, P14778, Q13651, P25025, Q16539, O00463 | TNF, ITPR1, PRKACB, GSK3B, IL1R1, IL10RA, CXCR2, MAPK14, TRAF5 | More | | | Prednisolone-phosphate | hsa05202 | Transcriptional misregulation in cancer | 3.51E-02 | 12 | P14780, P27930, Q15744, Q16548, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, P12980, P24522 | MMP9, IL1R2, CEBPE, BCL2A1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, LYL1, GADD45A | More | | | Prednisolone-phosphate | hsa05230 | Central carbon metabolism in cancer | 1.12E-02 | 1 | P11413 | G6PD | More | | | Prednisolone-phosphate | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 1.42E-02 | 7 | O95267, P20963, P09693, P06239, O60603, Q04759, Q16539 | RASGRP1, CD247, CD3G, LCK, TLR2, PRKCQ, MAPK14 | More | | | Prednisolone-phosphate | hsa05310 | Asthma | 1.62E-02 | 3 | P13765, P12724, P01375 | HLA-DOB, RNASE3, TNF | More | | | Prednisolone-phosphate | hsa05321 | Inflammatory bowel disease | 1.09E-03 | 6 | O60603, P01375, P13765, Q14765, Q9UL17, P23771 | TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3 | More | | | Prednisolone-phosphate | hsa05332 | Graft-versus-host disease | 1.76E-02 | 4 | P13765, P01375, P26715, Q13241 | HLA-DOB, TNF, KLRC1, KLRD1 | More | | | Prednisolone-phosphate | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.93E-02 | 1 | P54284 | CACNB3 | More | | | Prednisolone-phosphate | hsa05415 | Diabetic cardiomyopathy | 3.59E-02 | 1 | P11413 | G6PD | More | | | Prednisolone | hsa00030 | Pentose phosphate pathway | 8.97E-03 | 1 | P11413 | G6PD | More | | | Prednisolone | hsa00052 | Galactose metabolism | 1.03E-02 | 2 | P06280, O43451 | GLA, MGAM | More | | | Prednisolone | hsa00053 | Ascorbate and aldarate metabolism | 4.93E-02 | 1 | P14550 | AKR1A1 | More | | | Prednisolone | hsa00190 | Oxidative phosphorylation | 8.71E-03 | 3 | Q16718, Q13488, O14521 | NDUFA5, TCIRG1, SDHD | More | | | Prednisolone | hsa00480 | Glutathione metabolism | 1.35E-02 | 1 | P11413 | G6PD | More | | | Prednisolone | hsa00500 | Starch and sucrose metabolism | 1.67E-02 | 2 | O43451, P06737 | MGAM, PYGL | More | | | Prednisolone | hsa00565 | Ether lipid metabolism | 4.93E-02 | 1 | Q8N661 | TMEM86B | More | | | Prednisolone | hsa00590 | Arachidonic acid metabolism | 3.85E-02 | 2 | P11712, P09960 | CYP2C9, LTA4H | More | | | Prednisolone | hsa00591 | Linoleic acid metabolism | 4.07E-02 | 1 | P11712 | CYP2C9 | More | | | Prednisolone | hsa00730 | Thiamine metabolism | 5.29E-03 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Prednisolone | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 9.14E-03 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Prednisolone | hsa00982 | Drug metabolism - cytochrome P450 | 9.14E-03 | 2 | P11712, P78417 | CYP2C9, GSTO1 | More | | | Prednisolone | hsa00983 | Drug metabolism - other enzymes | 2.44E-02 | 2 | P32320, P05164 | CDA, MPO | More | | | Prednisolone | hsa01200 | Carbon metabolism | 2.91E-02 | 1 | P11413 | G6PD | More | | | Prednisolone | hsa02010 | ABC transporters | 4.93E-02 | 1 | Q8IZY2 | ABCA7 | More | | | Prednisolone | hsa04064 | NF-kappa B signaling pathway | 1.34E-03 | 8 | P10415, Q13489, Q13546, P29965, Q9UDY8, Q8WV28, Q13315, Q9UNE0 | BCL2, BIRC3, RIPK1, CD40LG, MALT1, BLNK, ATM, EDAR | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P01584 | IL1B | Interleukin-1 beta | P63279 | UBE2I | SUMO-conjugating enzyme UBC9 | 0.815 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P01584 | IL1B | Interleukin-1 beta | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.766 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 |
| | Prednisolone | hsa04070 | Phosphatidylinositol signaling system | 3.47E-02 | 4 | P0DP23, Q14643, P23743, P17252 | CALM1, ITPR1, DGKA, PRKCA | More | | | Prednisolone | hsa04071 | Sphingolipid signaling pathway | 2.87E-03 | 7 | P17252, Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2 | PRKCA, EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2 | More | | | Prednisolone | hsa04114 | Oocyte meiosis | 1.33E-02 | 4 | P51812, Q02750, P16298, Q17RY0 | RPS6KA3, MAP2K1, PPP3CB, CPEB4 | More | | | Prednisolone | hsa04145 | Phagosome | 1.59E-03 | 7 | Q15080, P14598, Q13509, P68371, Q13488, O60603, P13765 | NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, TLR2, HLA-DOB | More | | | Prednisolone | hsa04150 | mTOR signaling pathway | 3.60E-02 | 3 | Q02750, Q9NQL2, P51812 | MAP2K1, RRAGD, RPS6KA3 | More | | | Prednisolone | hsa04151 | PI3K-Akt signaling pathway | 4.50E-02 | 9 | P25116, P49767, Q13362, P62873, P16144, O60603, P01568, P10415, P17252 | F2R, VEGFC, PPP2R5C, GNB1, ITGB4, TLR2, IFNA21, BCL2, PRKCA | More | | | Prednisolone | hsa04210 | Apoptosis | 3.58E-02 | 4 | O76075, P01375, Q9NR28, Q16548 | DFFB, TNF, DIABLO, BCL2A1 | More | | | Prednisolone | hsa04211 | Longevity regulating pathway | 1.18E-02 | 3 | Q12778, Q9UEF7, Q96KQ7 | FOXO1, KL, EHMT2 | More | | | Prednisolone | hsa04213 | Longevity regulating pathway - multiple species | 2.85E-02 | 2 | Q9Y4H2, Q13547 | IRS2, HDAC1 | More | | | Prednisolone | hsa04217 | Necroptosis | 9.70E-04 | 8 | P01568, Q13489, Q13546, P42224, Q6FI13, P10415, O43633, Q08752 | IFNA21, BIRC3, RIPK1, STAT1, H2AC18; H2AC19, BCL2, CHMP2A, PPID | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P01584 | IL1B | Interleukin-1 beta | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | 0.799 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01584 | IL1B | Interleukin-1 beta | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.805 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P01584 | IL1B | Interleukin-1 beta | P0C0S5 | H2AFZ | Histone H2A.Z | 0.762 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | Q9H444 | CHMP4B | Charged multivesicular body protein 4b | 0.716 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O43633 | CHMP2A | Charged multivesicular body protein 2a | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone | hsa04261 | Adrenergic signaling in cardiomyocytes | 2.84E-02 | 5 | P09493, Q13362, P0DP23, P17252, P10415 | TPM1, PPP2R5C, CALM1, PRKCA, BCL2 | More | | | Prednisolone | hsa04340 | Hedgehog signaling pathway | 3.32E-02 | 2 | P49841, P22694 | GSK3B, PRKACB | More | | | Prednisolone | hsa04370 | VEGF signaling pathway | 2.68E-03 | 3 | P16298, Q05397, Q02750 | PPP3CB, PTK2, MAP2K1 | More | | | Prednisolone | hsa04530 | Tight junction | 3.29E-02 | 3 | P16989, P56750, Q14247 | CSDA, CLDN17, CTTN | More | | | Prednisolone | hsa04540 | Gap junction | 1.29E-02 | 4 | P17252, Q13509, P68371, Q14643 | PRKCA, TUBB3, TUBB2C, ITPR1 | More | | | Prednisolone | hsa04610 | Complement and coagulation cascades | 2.33E-03 | 1 | P0C0L4 | C4A | More | | | Prednisolone | hsa04612 | Antigen processing and presentation | 4.78E-02 | 6 | P48382, P26715, P26717, Q13241, O43908, P01375 | RFX5, KLRC1, KLRC2, KLRD1, KLRC4, TNF | More | | | Prednisolone | hsa04613 | Neutrophil extracellular trap formation | 4.29E-05 | 15 | P17252, P11215, O60603, P08246, Q13547, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431, P14598, Q15080, P21462 | PRKCA, ITGAM, TLR2, ELA2, HDAC1, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 | | P12429 | ANXA3 | Annexin A3 | O60603 | TLR2 | Toll-like receptor 2 | 0.702 | | P12429 | ANXA3 | Annexin A3 | P05164 | MPO | Myeloperoxidase | 0.815 | | P12429 | ANXA3 | Annexin A3 | P08246 | ELA2 | Neutrophil elastase | 0.741 | | P12429 | ANXA3 | Annexin A3 | Q9UM07 | PADI4 | Protein-arginine deiminase type-4 | 0.909 | | P12429 | ANXA3 | Annexin A3 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.765 | | P12429 | ANXA3 | Annexin A3 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.7 | | P12429 | ANXA3 | Annexin A3 | P20160 | AZU1 | Azurocidin | 0.804 | | P12429 | ANXA3 | Annexin A3 | P08311 | CTSG | Cathepsin G | 0.867 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P12429 | ANXA3 | Annexin A3 | P21730 | C5AR1 | C5a anaphylatoxin chemotactic receptor 1 | 0.887 | | P12429 | ANXA3 | Annexin A3 | O43315 | AQP9 | Aquaporin-9 | 0.789 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P11215 | ITGAM | Integrin alpha-M | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q13547 | HDAC1 | Histone deacetylase 1 | -0.711 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | P21462 | FPR1 | fMet-Leu-Phe receptor | -0.731 |
| | Prednisolone | hsa04620 | Toll-like receptor signaling pathway | 4.16E-02 | 2 | Q13546, P01568 | RIPK1, IFNA21 | More | | | Prednisolone | hsa04621 | NOD-like receptor signaling pathway | 4.48E-03 | 12 | P01568, Q13489, Q9H1Y0, P43490, O00463, Q13546, Q05823, P01375, P49913, P59665, P59666, P12838 | IFNA21, BIRC3, ATG5, PBEF1, TRAF5, RIPK1, RNASEL, TNF, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | Q16539 | MAPK14 | Mitogen-activated protein kinase 14 | 0.805 | | P12429 | ANXA3 | Annexin A3 | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | -0.75 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P12429 | ANXA3 | Annexin A3 | P10599 | TXN | Thioredoxin | 0.871 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P12429 | ANXA3 | Annexin A3 | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.717 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P12429 | ANXA3 | Annexin A3 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.908 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P12429 | ANXA3 | Annexin A3 | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.896 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P12429 | ANXA3 | Annexin A3 | P29728 | OAS2 | 2'-5'-oligoadenylate synthase 2 | -0.751 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P09341 | CXCL1 | Growth-regulated alpha protein | 0.892 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 | | P12429 | ANXA3 | Annexin A3 | P12838 | DEFA4 | Neutrophil defensin 4 | 0.899 | | P08235 | NR3C2 | Mineralocorticoid receptor | P01568 | IFNA21 | Interferon alpha-21 | 0.757 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P01375 | TNF | Tumor necrosis factor | Q9H1Y0 | ATG5 | Autophagy protein 5 | -0.811 | | P01375 | TNF | Tumor necrosis factor | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.78 | | P01375 | TNF | Tumor necrosis factor | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.816 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P01375 | TNF | Tumor necrosis factor | Q05823 | RNASEL | 2-5A-dependent ribonuclease | 0.853 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | P49913 | CAMP | Cathelicidin antimicrobial peptide | 0.774 | | P01375 | TNF | Tumor necrosis factor | P59665 | DEFA1; DEFA1B | Neutrophil defensin 1 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P59666 | DEFA3 | Neutrophil defensin 3 | 0.723 | | P01375 | TNF | Tumor necrosis factor | P12838 | DEFA4 | Neutrophil defensin 4 | 0.922 |
| | Prednisolone | hsa04622 | RIG-I-like receptor signaling pathway | 2.39E-02 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Prednisolone | hsa04623 | Cytosolic DNA-sensing pathway | 2.20E-03 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Prednisolone | hsa04650 | Natural killer cell mediated cytotoxicity | 7.08E-04 | 11 | P16298, P50591, P01375, O60880, P20963, Q02750, Q13241, P26718, O75015, P26717, P26715 | PPP3CB, TNFSF10, TNF, SH2D1A, CD247, MAP2K1, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P12429 | ANXA3 | Annexin A3 | P01375 | TNF | Tumor necrosis factor | 0.832 | | P12429 | ANXA3 | Annexin A3 | P06239 | LCK | Tyrosine-protein kinase Lck | -0.753 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P12429 | ANXA3 | Annexin A3 | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.833 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P12429 | ANXA3 | Annexin A3 | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.877 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P12429 | ANXA3 | Annexin A3 | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.84 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P12429 | ANXA3 | Annexin A3 | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.919 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P12429 | ANXA3 | Annexin A3 | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.816 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.83 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 | | P12429 | ANXA3 | Annexin A3 | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.83 | | P11511 | CYP19A1 | Aromatase | P16298 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 0.706 | | P11511 | CYP19A1 | Aromatase | P50591 | TNFSF10 | Tumor necrosis factor ligand superfamily member 10 | 0.701 | | P01375 | TNF | Tumor necrosis factor | P01375 | TNF | Tumor necrosis factor | 1 | | P01375 | TNF | Tumor necrosis factor | O60880 | SH2D1A | SH2 domain-containing protein 1A | -0.717 | | P01375 | TNF | Tumor necrosis factor | P20963 | CD247 | T-cell surface glycoprotein CD3 zeta chain | -0.727 | | P11511 | CYP19A1 | Aromatase | Q02750 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | 0.783 | | P01375 | TNF | Tumor necrosis factor | Q13241 | KLRD1 | Natural killer cells antigen CD94 | -0.769 | | P01375 | TNF | Tumor necrosis factor | P26718 | KLRK1 | NKG2-D type II integral membrane protein | -0.754 | | P01375 | TNF | Tumor necrosis factor | O75015 | FCGR3B | Low affinity immunoglobulin gamma Fc region receptor III-B | 0.838 | | P01375 | TNF | Tumor necrosis factor | P26717 | KLRC2 | NKG2-C type II integral membrane protein | -0.814 | | P01375 | TNF | Tumor necrosis factor | P26715 | KLRC1 | NKG2-A/NKG2-B type II integral membrane protein | -0.814 |
| | Prednisolone | hsa04657 | IL-17 signaling pathway | 3.31E-02 | 3 | P49841, P14780, P01375 | GSK3B, MMP9, TNF | More | | | Prednisolone | hsa04672 | Intestinal immune network for IgA production | 3.76E-03 | 3 | P29965, P10747, P13765 | CD40LG, CD28, HLA-DOB | More | | | Prednisolone | hsa04713 | Circadian entrainment | 2.60E-02 | 4 | P0DP23, P17252, P62873, Q14643 | CALM1, PRKCA, GNB1, ITPR1 | More | | | Prednisolone | hsa04720 | Long-term potentiation | 1.95E-03 | 6 | P17252, P16298, P0DP23, P51812, Q02750, Q14643 | PRKCA, PPP3CB, CALM1, RPS6KA3, MAP2K1, ITPR1 | More | | | Prednisolone | hsa04723 | Retrograde endocannabinoid signaling | 1.88E-02 | 4 | Q14643, P17252, P62873, Q16718 | ITPR1, PRKCA, GNB1, NDUFA5 | More | | | Prednisolone | hsa04725 | Cholinergic synapse | 1.88E-02 | 4 | Q14643, P17252, P62873, P10415 | ITPR1, PRKCA, GNB1, BCL2 | More | | | Prednisolone | hsa04728 | Dopaminergic synapse | 3.55E-02 | 5 | Q14643, P17252, P62873, Q13362, P0DP23 | ITPR1, PRKCA, GNB1, PPP2R5C, CALM1 | More | | | Prednisolone | hsa04744 | Phototransduction | 1.02E-02 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | | | Prednisolone | hsa04910 | Insulin signaling pathway | 2.35E-02 | 3 | P22694, P06737, P49841 | PRKACB, PYGL, GSK3B | More | | | Prednisolone | hsa04912 | GnRH signaling pathway | 3.89E-02 | 3 | P17252, Q14643, P0DP23 | PRKCA, ITPR1, CALM1 | More | | | Prednisolone | hsa04914 | Progesterone-mediated oocyte maturation | 2.94E-02 | 3 | Q17RY0, P51812, Q02750 | CPEB4, RPS6KA3, MAP2K1 | More | | | Prednisolone | hsa04919 | Thyroid hormone signaling pathway | 7.11E-03 | 4 | P49841, P22694, O60244, Q9NVC6 | GSK3B, PRKACB, MED14, MED17 | More | | | Prednisolone | hsa04922 | Glucagon signaling pathway | 3.47E-02 | 4 | Q12778, Q13370, P0DP23, Q14643 | FOXO1, PDE3B, CALM1, ITPR1 | More | | | Prednisolone | hsa04924 | Renin secretion | 8.71E-03 | 3 | Q14643, Q13370, P0DP23 | ITPR1, PDE3B, CALM1 | More | | | Prednisolone | hsa04931 | Insulin resistance | 1.94E-02 | 3 | P01375, P49841, P06737 | TNF, GSK3B, PYGL | More | | | Prednisolone | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 1.27E-02 | 5 | P42224, P10415, Q12778, P49767, P17252 | STAT1, BCL2, FOXO1, VEGFC, PRKCA | More | | | Prednisolone | hsa04964 | Proximal tubule bicarbonate reclamation | 4.93E-02 | 1 | P00918 | CA2 | More | | | Prednisolone | hsa04966 | Collecting duct acid secretion | 2.07E-03 | 3 | Q13488, P00918, Q9Y666 | TCIRG1, CA2, SLC12A7 | More | | | Prednisolone | hsa04975 | Fat digestion and absorption | 2.80E-02 | 1 | O14494 | PLPP1 | More | | | Prednisolone | hsa04976 | Bile secretion | 2.44E-02 | 2 | P22694, P08183 | PRKACB, ABCB1 | More | | | Prednisolone | hsa05010 | Alzheimer disease | 3.55E-02 | 7 | Q16718, O14521, Q14643, P0DP23, Q13509, P68371, Q08752 | NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2C, PPID | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q92542 | NCSTN | Nicastrin | 0.706 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P05496 | ATP5G1 | ATP synthase F(0) complex subunit C1, mitochondrial | 0.733 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.754 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.731 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P01584 | IL1B | Interleukin-1 beta | 0.75 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | O15169 | AXIN1 | Axin-1 | 0.742 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P45880 | VDAC2 | Voltage-dependent anion-selective channel protein 2 | 0.708 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone | hsa05012 | Parkinson disease | 2.25E-02 | 6 | Q16718, O14521, Q14643, P0DP23, Q13509, P68371 | NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2C | More | | | Prednisolone | hsa05020 | Prion disease | 1.15E-02 | 7 | Q16718, O14521, Q14643, Q13509, P68371, P14598, Q15080 | NDUFA5, SDHD, ITPR1, TUBB3, TUBB2C, NCF1, NCF4 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P01584 | IL1B | Interleukin-1 beta | 0.75 | | P01584 | IL1B | Interleukin-1 beta | P46531 | NOTCH1 | Neurogenic locus notch homolog protein 1 | 0.827 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P46531 | NOTCH1 | Neurogenic locus notch homolog protein 1 | 0.706 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P11142 | HSPA8 | Heat shock cognate 71 kDa protein | 0.766 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P05496 | ATP5G1 | ATP synthase F(0) complex subunit C1, mitochondrial | 0.733 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.754 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P45880 | VDAC2 | Voltage-dependent anion-selective channel protein 2 | 0.708 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P01584 | IL1B | Interleukin-1 beta | Q99941 | CREBL1 | Cyclic AMP-dependent transcription factor ATF-6 beta | 0.704 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q99941 | CREBL1 | Cyclic AMP-dependent transcription factor ATF-6 beta | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P14598 | NCF1 | Neutrophil cytosol factor 1 | -0.821 | | P17252 | PRKCA | Protein kinase C alpha type | Q15080 | NCF4 | Neutrophil cytosol factor 4 | -0.836 |
| | Prednisolone | hsa05022 | Pathways of neurodegeneration - multiple diseases | 4.48E-03 | 10 | Q14643, Q13509, P68371, P10415, Q16718, O14521, Q13561, P17252, Q08752, P0DP23 | ITPR1, TUBB3, TUBB2C, BCL2, NDUFA5, SDHD, DCTN2, PRKCA, PPID, CALM1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P01584 | IL1B | Interleukin-1 beta | O15239 | NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P01584 | IL1B | Interleukin-1 beta | P12074 | COX6A1 | Cytochrome c oxidase subunit 6A1, mitochondrial | 0.744 | | P01584 | IL1B | Interleukin-1 beta | Q8TEV9 | SMCR8 | Guanine nucleotide exchange protein SMCR8 | 0.705 | | P01584 | IL1B | Interleukin-1 beta | O75460 | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1 | 0.826 | | P01584 | IL1B | Interleukin-1 beta | P18848 | ATF4 | Cyclic AMP-dependent transcription factor ATF-4 | 0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P01584 | IL1B | Interleukin-1 beta | P05141 | SLC25A5 | ADP/ATP translocase 2 | 0.768 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P01584 | IL1B | Interleukin-1 beta | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | 0.735 | | P01584 | IL1B | Interleukin-1 beta | O15169 | AXIN1 | Axin-1 | 0.7 | | P01584 | IL1B | Interleukin-1 beta | P01584 | IL1B | Interleukin-1 beta | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P01584 | IL1B | Interleukin-1 beta | P0DP24 | CALM2 | Calmodulin-2 | 0.72 | | P01584 | IL1B | Interleukin-1 beta | Q13557 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | 0.725 | | P01584 | IL1B | Interleukin-1 beta | P28070 | PSMB4 | Proteasome subunit beta type-4 | 0.734 | | P01584 | IL1B | Interleukin-1 beta | P43686 | PSMC4 | 26S proteasome regulatory subunit 6B | 0.723 | | P08758 | ANXA5 | Annexin A5 | Q06055 | ATP5G2 | ATP synthase F(0) complex subunit C2, mitochondrial | 0.731 | | P08758 | ANXA5 | Annexin A5 | P17861 | XBP1 | X-box-binding protein 1 | 0.779 | | P08758 | ANXA5 | Annexin A5 | P62195 | PSMC5 | 26S proteasome regulatory subunit 8 | 0.814 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q16718 | NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | 0.811 | | P17252 | PRKCA | Protein kinase C alpha type | O14521 | SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | 0.822 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 |
| | Prednisolone | hsa05034 | Alcoholism | 2.05E-05 | 7 | Q13547, Q93077, P58876, P62807, Q16778, O60814, P68431 | HDAC1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | | Prednisolone | hsa05131 | Shigellosis | 2.27E-02 | 8 | P68431, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | Q05655 | PRKCD | Protein kinase C delta type | Q05655 | PRKCD | Protein kinase C delta type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 | | Q05655 | PRKCD | Protein kinase C delta type | P07737 | PFN1 | Profilin-1 | 0.77 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P17252 | PRKCA | Protein kinase C alpha type | Q14247 | CTTN | Src substrate cortactin | 0.771 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q08752 | PPID | Peptidyl-prolyl cis-trans isomerase D | 0.725 |
| | Prednisolone | hsa05132 | Salmonella infection | 5.51E-04 | 10 | Q9UJU2, Q13546, Q13489, P10415, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371 | LEF1, RIPK1, BIRC3, BCL2, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2C | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | Q05655 | PRKCD | Protein kinase C delta type | P84095 | RHOG | Rho-related GTP-binding protein RhoG | 0.71 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | Q05655 | PRKCD | Protein kinase C delta type | P07737 | PFN1 | Profilin-1 | 0.77 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q9BQS8 | FYCO1 | FYVE and coiled-coil domain-containing protein 1 | 0.701 | | P17252 | PRKCA | Protein kinase C alpha type | Q13561 | DCTN2 | Dynactin subunit 2 | -0.844 | | P08235 | NR3C2 | Mineralocorticoid receptor | O60282 | KIF5C | Kinesin heavy chain isoform 5C | 0.753 | | P17252 | PRKCA | Protein kinase C alpha type | Q13509 | TUBB3 | Tubulin beta-3 chain | -0.756 | | P17252 | PRKCA | Protein kinase C alpha type | P68371 | TUBB2C | Tubulin beta-4B chain | -0.842 | | P08235 | NR3C2 | Mineralocorticoid receptor | P68371 | TUBB2C | Tubulin beta-4B chain | -0.747 |
| | Prednisolone | hsa05133 | Pertussis | 4.20E-02 | 1 | P0C0L4 | C4A | More | | | Prednisolone | hsa05140 | Leishmaniasis | 2.17E-03 | 6 | P14598, P42224, P13765, O60603, P29350, Q15080 | NCF1, STAT1, HLA-DOB, TLR2, PTPN6, NCF4 | More | | | Prednisolone | hsa05143 | African trypanosomiasis | 1.31E-02 | 2 | P69905, P68871 | HBA2, HBB | More | | | Prednisolone | hsa05144 | Malaria | 3.76E-03 | 6 | P60033, P69905, P68871, P01375, P35443, P26718 | CD81, HBA2, HBB, TNF, THBS4, KLRK1 | More | | | Prednisolone | hsa05145 | Toxoplasmosis | 1.11E-02 | 6 | P10415, Q13489, P42224, P13765, O60603, P29965 | BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LG | More | | | Prednisolone | hsa05150 | Staphylococcus aureus infection | 1.02E-03 | 7 | P21730, P21462, O75015, P59665, P59666, P12838, P49913 | C5AR1, FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMP | More | | | Prednisolone | hsa05152 | Tuberculosis | 7.93E-04 | 8 | Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8 | TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1 | More | | | Prednisolone | hsa05165 | Human papillomavirus infection | 3.10E-02 | 8 | P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315 | ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATM | More | | | Prednisolone | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 3.04E-03 | 10 | P01568, P42224, P62873, P62879, P16298, Q14643, Q02750, P0DP23, P0CG47, Q9UJU2 | IFNA21, STAT1, GNB1, GNB2, PPP3CB, ITPR1, MAP2K1, CALM1, UBB, LEF1 | More | | | Prednisolone | hsa05170 | Human immunodeficiency virus 1 infection | 8.44E-05 | 14 | Q02750, P62873, P62879, P16298, P0DP23, Q05397, P17252, Q14643, P01568, O60603, Q13315, P10415, Q9Y6Q5, P20333 | MAP2K1, GNB1, GNB2, PPP3CB, CALM1, PTK2, PRKCA, ITPR1, IFNA21, TLR2, ATM, BCL2, AP1M2, TNFRSF1B | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P11511 | CYP19A1 | Aromatase | Q02750 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | 0.783 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P11511 | CYP19A1 | Aromatase | P62879 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | 0.704 | | P11511 | CYP19A1 | Aromatase | P16298 | PPP3CB | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform | 0.706 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P11511 | CYP19A1 | Aromatase | Q05397 | PTK2 | Focal adhesion kinase 1 | 0.75 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | Q14643 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | 0.786 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | O60603 | TLR2 | Toll-like receptor 2 | -0.716 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q9Y6Q5 | AP1M2 | AP-1 complex subunit mu-2 | -0.829 | | P11511 | CYP19A1 | Aromatase | P20333 | TNFRSF1B | Tumor necrosis factor receptor superfamily member 1B | -0.75 |
| | Prednisolone | hsa05200 | Pathways in cancer | 4.99E-02 | 12 | P42224, Q9UJU2, P17252, P14923, P10415, Q13489, P49767, Q12778, P25116, P62873, P0DP23, P01568 | STAT1, LEF1, PRKCA, JUP, BCL2, BIRC3, VEGFC, FOXO1, F2R, GNB1, CALM1, IFNA21 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 | | P17252 | PRKCA | Protein kinase C alpha type | P42224 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | -0.706 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UJU2 | LEF1 | Lymphoid enhancer-binding factor 1 | 0.881 | | P17252 | PRKCA | Protein kinase C alpha type | P17252 | PRKCA | Protein kinase C alpha type | 1 | | P17252 | PRKCA | Protein kinase C alpha type | P14923 | JUP | Junction plakoglobin | 0.761 | | P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P17252 | PRKCA | Protein kinase C alpha type | P49767 | VEGFC | Vascular endothelial growth factor C | 0.719 | | P17252 | PRKCA | Protein kinase C alpha type | Q12778 | FOXO1 | Forkhead box protein O1 | 0.863 | | P17252 | PRKCA | Protein kinase C alpha type | P25116 | F2R | Proteinase-activated receptor 1 | 0.857 | | P17252 | PRKCA | Protein kinase C alpha type | P62873 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | -0.852 | | P17252 | PRKCA | Protein kinase C alpha type | P0DP23 | CALM1 | Calmodulin-1 | -0.776 | | P17252 | PRKCA | Protein kinase C alpha type | P01568 | IFNA21 | Interferon alpha-21 | 0.733 |
| | Prednisolone | hsa05202 | Transcriptional misregulation in cancer | 1.24E-02 | 4 | P27930, P11215, Q13547, P12980 | IL1R2, ITGAM, HDAC1, LYL1 | More | | | Prednisolone | hsa05203 | Viral carcinogenesis | 1.22E-03 | 6 | Q13547, Q15283, P58876, P62807, Q16778, O60814 | HDAC1, RASA2, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12 | More | | | Prednisolone | hsa05204 | Chemical carcinogenesis | 1.48E-02 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | | | Prednisolone | hsa05213 | Endometrial cancer | 3.79E-02 | 2 | O15169, Q02750 | AXIN1, MAP2K1 | More | | | Prednisolone | hsa05226 | Gastric cancer | 3.79E-02 | 2 | Q02750, O15169 | MAP2K1, AXIN1 | More | | | Prednisolone | hsa05230 | Central carbon metabolism in cancer | 1.12E-02 | 1 | P11413 | G6PD | More | | | Prednisolone | hsa05320 | Autoimmune thyroid disease | 1.27E-03 | 4 | P13765, P29965, P01568, P10747 | HLA-DOB, CD40LG, IFNA21, CD28 | More | | | Prednisolone | hsa05322 | Systemic lupus erythematosus | 2.33E-07 | 12 | P08246, P09871, P10747, P13765, P29965, Q6FI13, Q93077, P58876, P62807, Q16778, O60814, P68431 | ELA2, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 | | P17252 | PRKCA | Protein kinase C alpha type | P08246 | ELA2 | Neutrophil elastase | -0.735 | | P17252 | PRKCA | Protein kinase C alpha type | P09871 | C1S | Complement C1s subcomponent | 0.744 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P09871 | C1S | Complement C1s subcomponent | 0.702 | | P17252 | PRKCA | Protein kinase C alpha type | P10747 | CD28 | T-cell-specific surface glycoprotein CD28 | 0.82 | | P17252 | PRKCA | Protein kinase C alpha type | P13765 | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain | 0.709 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P17252 | PRKCA | Protein kinase C alpha type | Q6FI13 | H2AC18; H2AC19 | Histone H2A type 2-A | -0.83 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | Q93077 | HIST1H2AC | Histone H2A type 1-C | 0.754 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | P58876 | H2BC5 | Histone H2B type 1-D | 0.947 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P62807 | HIST1H2BC | Histone H2B type 1-C/E/F/G/I | 0.717 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | Q16778 | HIST2H2BE | Histone H2B type 2-E | 0.793 | | O15245 | SLC22A1 | Solute carrier family 22 member 1 | O60814 | H2BC12 | Histone H2B type 1-K | 0.72 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | O60814 | H2BC12 | Histone H2B type 1-K | 0.728 | | P17252 | PRKCA | Protein kinase C alpha type | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.783 | | P11712 | CYP2C9 | Cytochrome P450 2C9 | P68431 | H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | Histone H3.1 | 0.845 |
| | Prednisolone | hsa05323 | Rheumatoid arthritis | 1.29E-02 | 4 | P13765, Q13488, P10747, O60603 | HLA-DOB, TCIRG1, CD28, TLR2 | More | | | Prednisolone | hsa05330 | Allograft rejection | 1.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | | | Prednisolone | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.93E-02 | 1 | P54284 | CACNB3 | More | | | Prednisolone | hsa05415 | Diabetic cardiomyopathy | 2.33E-02 | 6 | P17252, P14598, Q15080, Q16718, O14521, P11413 | PRKCA, NCF1, NCF4, NDUFA5, SDHD, G6PD | More | | | Prednisolone | hsa05416 | Viral myocarditis | 2.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | |
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