PharmaCoNets of Pralidoxime (SPCN: 0.42 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Pralidoximehsa00830Retinol metabolism3.49E-021P00325ADH1BMore
Pralidoximehsa04014Ras signaling pathway4.65E-023Q15311, P0DP23, P17612RALBP1, CALM1, PRKACAMore
Pralidoximehsa04114Oocyte meiosis2.15E-023P0DP23, P17612, Q13362CALM1, PRKACA, PPP2R5CMore
Pralidoximehsa04144Endocytosis4.07E-035Q9H444, O75351, P42566, Q15438, Q14161CHMP4B, VPS4B, EPS15, PSCD1, GIT2More
Pralidoximehsa04217Necroptosis4.56E-034P23458, Q9NQC7, Q9H444, O75351JAK1, CYLD, CHMP4B, VPS4BMore
Pralidoximehsa04261Adrenergic signaling in cardiomyocytes2.50E-023P17612, Q13362, P0DP23PRKACA, PPP2R5C, CALM1More
Pralidoximehsa04713Circadian entrainment4.42E-022P0DP23, P17612CALM1, PRKACAMore
Pralidoximehsa04720Long-term potentiation4.42E-022P0DP23, P17612CALM1, PRKACAMore
Pralidoximehsa04728Dopaminergic synapse1.55E-023P17612, Q13362, P0DP23PRKACA, PPP2R5C, CALM1More
Pralidoximehsa04740Olfactory transduction6.71E-032P0DP23, P17612CALM1, PRKACAMore
Pralidoximehsa04910Insulin signaling pathway3.62E-022P0DP23, P17612CALM1, PRKACAMore
Pralidoximehsa04916Melanogenesis2.87E-022P17612, P0DP23PRKACA, CALM1More
Pralidoximehsa04921Oxytocin signaling pathway1.84E-023P0DP23, P17612, Q96RR4CALM1, PRKACA, CAMKK2More
Pralidoximehsa04924Renin secretion1.09E-022P17612, P0DP23PRKACA, CALM1More
Pralidoximehsa04970Salivary secretion2.20E-022P17612, P0DP23PRKACA, CALM1More
Pralidoximehsa04971Gastric acid secretion2.87E-022P17612, P0DP23PRKACA, CALM1More
Pralidoximehsa04976Bile secretion2.20E-022P17612, Q14032PRKACA, BAATMore
Pralidoximehsa05031Amphetamine addiction2.87E-022P0DP23, P17612CALM1, PRKACAMore
Pralidoximehsa05034Alcoholism1.29E-023P17612, P0DP23, Q96RR4PRKACA, CALM1, CAMKK2More
Pralidoximehsa05212Pancreatic cancer2.87E-022Q15311, P23458RALBP1, JAK1More

Community members of Pralidoxime (SDC: 0.19)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q8NFZ4NLGN2NeuroliginNone2Predicted00.5660.06920.16270.5841
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)