PharmaCoNets of Pirbuterol (SPCN: 9.48 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Pirbuterolhsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Pirbuterolhsa00052Galactose metabolism1.51E-021P16278GLB1More
Pirbuterolhsa00511Other glycan degradation9.09E-031P16278GLB1More
Pirbuterolhsa00520Amino sugar and nucleotide sugar metabolism6.13E-033Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Pirbuterolhsa00531Glycosaminoglycan degradation1.51E-021P16278GLB1More
Pirbuterolhsa00600Sphingolipid metabolism1.81E-021P16278GLB1More
Pirbuterolhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series3.60E-032P06865, O75752HEXA, B3GALNT1More
Pirbuterolhsa00604Glycosphingolipid biosynthesis - ganglio series9.09E-031P16278GLB1More
Pirbuterolhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Pirbuterolhsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Pirbuterolhsa03030DNA replication1.81E-021P15927RPA2More
Pirbuterolhsa03420Nucleotide excision repair1.51E-021P15927RPA2More
Pirbuterolhsa03430Mismatch repair1.81E-021P15927RPA2More
Pirbuterolhsa03440Homologous recombination1.81E-021P15927RPA2More
Pirbuterolhsa03460Fanconi anemia pathway1.81E-021P15927RPA2More
Pirbuterolhsa04071Sphingolipid signaling pathway1.19E-024P21453, Q9H228, P01375, Q13362S1PR1, EDG8, TNF, PPP2R5CMore
Pirbuterolhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Pirbuterolhsa04114Oocyte meiosis1.92E-024Q9Y6D9, P51812, Q02750, Q14738MAD1L1, RPS6KA3, MAP2K1, PPP2R5DMore
Pirbuterolhsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Pirbuterolhsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Pirbuterolhsa04650Natural killer cell mediated cytotoxicity5.05E-047P01375, P20963, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Pirbuterolhsa04657IL-17 signaling pathway2.41E-024P19875, P14780, P80188, P01375CXCL2, MMP9, LCN2, TNFMore
Pirbuterolhsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Pirbuterolhsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Pirbuterolhsa04742Taste transduction1.01E-021P30939HTR1FMore
Pirbuterolhsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Pirbuterolhsa04914Progesterone-mediated oocyte maturation3.88E-023Q9Y6D9, P51812, Q02750MAD1L1, RPS6KA3, MAP2K1More
Pirbuterolhsa04919Thyroid hormone signaling pathway2.44E-023Q02750, Q15788, P08237MAP2K1, NCOA1, PFKMMore
Pirbuterolhsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Pirbuterolhsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Pirbuterolhsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Pirbuterolhsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Pirbuterolhsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Pirbuterolhsa05144Malaria1.91E-023P01375, P35443, P26718TNF, THBS4, KLRK1More
Pirbuterolhsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Pirbuterolhsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Pirbuterolhsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Pirbuterolhsa05332Graft-versus-host disease8.79E-033P01375, P26715, Q13241TNF, KLRC1, KLRD1More

Community members of Pirbuterol (SDC: 1.95)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P07550ADRB2BetaNone2 adrenergic receptorReported00.007110.22052.224
P16278GLB1BetaNonegalactosidasePredicted10.6880.02440.3220.7148
P06865HEXABetaNonehexosaminidase subunit alphaPredicted00.0690.02840.32080.4122
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)