PharmaCoNets
.
Phenazopyridine
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PharmaCoNets of Phenazopyridine (S
PCN
: 1.25 )
Phenazopyridine regulated-network (S
DN
: 0.57)
Drug Name
Pathway ID
Pathway name
P-value
No. of gene members
UniProt AC
Gene name
Detail of Coexpression
Phenazopyridine
hsa01523
Antifolate resistance
1.68E-02
2
Q92820, P04818
GGH, TYMS
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P06493
CDK1
Cyclin-dependent kinase 1
Q92820
GGH
Gamma-glutamyl hydrolase
0.712
P06493
CDK1
Cyclin-dependent kinase 1
P04818
TYMS
Thymidylate synthase
0.753
Phenazopyridine
hsa04110
Cell cycle
6.63E-04
6
P06493, O60566, P30304, P33981, P42773, P01106
CDK1, BUB1B, CDC25A, TTK, CDKN2C, MYC
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P06493
CDK1
Cyclin-dependent kinase 1
P06493
CDK1
Cyclin-dependent kinase 1
1
P06493
CDK1
Cyclin-dependent kinase 1
O60566
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
0.726
P06493
CDK1
Cyclin-dependent kinase 1
P30304
CDC25A
M-phase inducer phosphatase 1
0.724
P06493
CDK1
Cyclin-dependent kinase 1
P33981
TTK
Dual specificity protein kinase TTK
0.893
P06493
CDK1
Cyclin-dependent kinase 1
P42773
CDKN2C
Cyclin-dependent kinase 4 inhibitor C
0.722
P06493
CDK1
Cyclin-dependent kinase 1
P01106
MYC
Myc proto-oncogene protein
-0.733
Phenazopyridine
hsa04640
Hematopoietic cell lineage
4.95E-02
3
P01730, P06127, P09564
CD4, CD5, CD7
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P06493
CDK1
Cyclin-dependent kinase 1
P01730
CD4
T-cell surface glycoprotein CD4
-0.732
P06493
CDK1
Cyclin-dependent kinase 1
P06127
CD5
T-cell surface glycoprotein CD5
-0.739
P06493
CDK1
Cyclin-dependent kinase 1
P09564
CD7
T-cell antigen CD7
-0.735
Community members of Phenazopyridine (S
DC
: 2.18)
UniProtAC
Gene Name
Protein Name
Reported/
Predicted
DisGeNET
S
PV
S
drugability
S
HiSBiN
S
DisG
P06493
CDK1
CyclinNonedependent kinase 1
Predicted
0
0.013
1
0.604
2.6105
BDBM ID
C.S.
Homologus UniProt ID
Gene Name
I.S.
Text mining Similar drug DB ID
C.S.
BDBM12024
0.897
None
None
None
None
None
This pair is Reported in Drugbank.
Gene name
UniProt_ID
Bioactivity
Value (nM)