Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
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Pentagastrin | hsa00052 | Galactose metabolism | 3.41E-02 | 2 | O43451, Q14376 | MGAM, GALE | More | | Pentagastrin | hsa00190 | Oxidative phosphorylation | 2.29E-02 | 2 | Q16718, O14521 | NDUFA5, SDHD | More | | Pentagastrin | hsa00512 | Mucin type O-glycan biosynthesis | 3.78E-02 | 2 | O95395, Q8N4A0 | GCNT3, GALNT4 | More | | Pentagastrin | hsa00531 | Glycosaminoglycan degradation | 3.53E-02 | 1 | P15586 | GNS | More | | Pentagastrin | hsa00533 | Glycosaminoglycan biosynthesis - keratan sulfate | 1.91E-02 | 1 | Q9NY97 | B3GNT2 | More | | Pentagastrin | hsa00601 | Glycosphingolipid biosynthesis - lacto and neolacto series | 3.78E-02 | 1 | Q9NY97 | B3GNT2 | More | | Pentagastrin | hsa00770 | Pantothenate and CoA biosynthesis | 1.15E-02 | 2 | O95498, Q9NRN7 | VNN2, AASDHPPT | More | | Pentagastrin | hsa00970 | Aminoacyl-tRNA biosynthesis | 2.43E-03 | 2 | O95363, Q15046 | FARS2, KARS | More | | Pentagastrin | hsa01100 | Metabolic pathways | 4.11E-02 | 7 | P30041, P20839, P08237, Q86XP1, Q9UHK6, Q86VZ5, Q9NVH6 | PRDX6, IMPDH1, PFKM, DGKH, AMACR, SGMS1, TMLHE | More | | Pentagastrin | hsa01210 | 2-Oxocarboxylic acid metabolism | 1.91E-02 | 1 | P50213 | IDH3A | More | | Pentagastrin | hsa01524 | Platinum drug resistance | 2.64E-03 | 3 | P04637, Q14790, P48023 | TP53, CASP8, FASLG | More | | Pentagastrin | hsa02010 | ABC transporters | 2.29E-02 | 2 | P45844, P08183 | ABCG1, ABCB1 | More | | Pentagastrin | hsa03010 | Ribosome | 3.41E-02 | 2 | P46777, P50914 | RPL5, RPL14 | More | | Pentagastrin | hsa03013 | RNA transport | 1.14E-03 | 13 | O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, Q9Y6A5, P51114 | XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, TACC3, FXR1 | More | | Pentagastrin | hsa03022 | Basal transcription factors | 3.32E-02 | 2 | O00268, Q15544 | TAF4, TAF11 | More | | Pentagastrin | hsa03040 | Spliceosome | 1.28E-05 | 13 | O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643 | DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1 | More | | Pentagastrin | hsa03060 | Protein export | 1.90E-02 | 2 | Q15070, O76094 | OXA1L, SRP72 | More | | Pentagastrin | hsa04010 | MAPK signaling pathway | 3.58E-02 | 6 | Q8IZS8, Q16539, P24522, P14778, P49407, P01106 | CACNA2D3, MAPK14, GADD45A, IL1R1, ARRB1, MYC | More | | Pentagastrin | hsa04014 | Ras signaling pathway | 2.36E-02 | 8 | P42338, P20827, P49767, Q13009, Q7LDG7, P63218, P50151, P19174 | PIK3CB, EFNA1, VEGFC, TIAM1, RASGRP2, GNG5, GNG10, PLCG1 | More | | Pentagastrin | hsa04015 | Rap1 signaling pathway | 1.98E-03 | 11 | P20827, P49767, Q96FS4, P11215, P25116, Q8TEU7, Q13009, Q7LDG7, P42338, P08514, P19174 | EFNA1, VEGFC, SIPA1, ITGAM, F2R, RAPGEF6, TIAM1, RASGRP2, PIK3CB, ITGA2B, PLCG1 | More | | Pentagastrin | hsa04022 | cGMP-PKG signaling pathway | 1.05E-02 | 3 | P24844, Q8WYR1, Q15746 | MYL9, PIK3R5, MYLK | More | | Pentagastrin | hsa04024 | cAMP signaling pathway | 1.40E-02 | 3 | P48058, P25116, P24844 | GRIA4, F2R, MYL9 | More | | Pentagastrin | hsa04062 | Chemokine signaling pathway | 9.23E-03 | 10 | P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q7LDG7, Q13009, Q8WYR1 | FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, RASGRP2, TIAM1, PIK3R5 | More | | Pentagastrin | hsa04064 | NF-kappa B signaling pathway | 1.91E-04 | 12 | P10415, Q13489, P25963, P51617, O00463, P01375, Q04759, Q9UDY8, Q13077, Q16548, Q13315, P24522 | BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, TNF, PRKCQ, MALT1, TRAF1, BCL2A1, ATM, GADD45A | More | | Pentagastrin | hsa04068 | FoxO signaling pathway | 1.02E-02 | 2 | P48023, Q96BR1 | FASLG, SGK3 | More | | Pentagastrin | hsa04071 | Sphingolipid signaling pathway | 1.63E-03 | 7 | P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, P10415 | PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, BCL2 | More | | Pentagastrin | hsa04080 | Neuroactive ligand-receptor interaction | 1.18E-02 | 7 | P08311, Q15722, P21453, Q9H228, O00398, P21462, P21730 | CTSG, LTB4R, S1PR1, EDG8, P2RY10, FPR1, C5AR1 | More | | Pentagastrin | hsa04110 | Cell cycle | 1.21E-02 | 7 | P06493, O60566, P24522, P49918, P30304, P42773, P01106 | CDK1, BUB1B, GADD45A, CDKN1C, CDC25A, CDKN2C, MYC | More | | Pentagastrin | hsa04115 | p53 signaling pathway | 7.60E-03 | 7 | P24522, Q13315, Q53FA7, Q14790, P04637, O95067, P10415 | GADD45A, ATM, TP53I3, CASP8, TP53, CCNB2, BCL2 | More | | Pentagastrin | hsa04120 | Ubiquitin mediated proteolysis | 3.44E-02 | 4 | Q14145, Q13042, P62837, Q15751 | KEAP1, CDC16, UBE2D2, HERC1 | More | | Pentagastrin | hsa04145 | Phagosome | 1.98E-02 | 8 | Q15080, P14598, Q13509, Q13488, P05164, O60603, P35443, P13765 | NCF4, NCF1, TUBB3, TCIRG1, MPO, TLR2, THBS4, HLA-DOB | More | | Pentagastrin | hsa04151 | PI3K-Akt signaling pathway | 3.32E-03 | 15 | P42338, P43657, P48023, P04637, P20827, P49767, P08238, Q8WYR1, P63218, P50151, O15335, Q13751, P14784, Q96BR1, P30281 | PIK3CB, P2RY5, FASLG, TP53, EFNA1, VEGFC, HSP90AB1, PIK3R5, GNG5, GNG10, CHAD, LAMB3, IL2RB, SGK3, CCND3 | More | | Pentagastrin | hsa04210 | Apoptosis | 8.06E-04 | 13 | Q13315, P04637, P10415, Q13489, P25963, Q14790, P01375, P48023, P24522, Q16548, Q13077, Q14643, P42575 | ATM, TP53, BCL2, BIRC3, NFKBIA, CASP8, TNF, FASLG, GADD45A, BCL2A1, TRAF1, ITPR1, CASP2 | More | | Pentagastrin | hsa04217 | Necroptosis | 2.34E-02 | 4 | P01375, P48023, Q14765, Q99878 | TNF, FASLG, STAT4, H2AC14 | More | | Pentagastrin | hsa04218 | Cellular senescence | 1.33E-02 | 6 | P01106, Q9H422, Q16539, P24522, P30304, P06493 | MYC, HIPK3, MAPK14, GADD45A, CDC25A, CDK1 | More | | Pentagastrin | hsa04270 | Vascular smooth muscle contraction | 4.65E-02 | 2 | Q15746, P24844 | MYLK, MYL9 | More | | Pentagastrin | hsa04330 | Notch signaling pathway | 7.49E-03 | 2 | Q92542, P49768 | NCSTN, PSEN1 | More | | Pentagastrin | hsa04360 | Axon guidance | 4.04E-02 | 6 | P16333, P20827, O95631, P42338, P07332, P19174 | NCK1, EFNA1, NTN1, PIK3CB, FES, PLCG1 | More | | Pentagastrin | hsa04371 | Apelin signaling pathway | 1.00E-02 | 7 | P63218, P50151, Q8WYR1, Q14814, Q14344, Q13485, P84022 | GNG5, GNG10, PIK3R5, MEF2D, GNA13, SMAD4, SMAD3 | More | | Pentagastrin | hsa04390 | Hippo signaling pathway | 4.35E-02 | 2 | P63261, O15105 | ACTG1, SMAD7 | More | | Pentagastrin | hsa04510 | Focal adhesion | 3.36E-02 | 3 | P08514, Q15746, P24844 | ITGA2B, MYLK, MYL9 | More | | Pentagastrin | hsa04512 | ECM-receptor interaction | 2.44E-02 | 2 | P07359, P08514 | GP1BA, ITGA2B | More | | Pentagastrin | hsa04514 | Cell adhesion molecules | 4.65E-02 | 2 | P16109, O00501 | SELP, CLDN5 | More | | Pentagastrin | hsa04530 | Tight junction | 9.34E-05 | 6 | Q8TEU7, P63261, O00501, Q92974, Q14247, P24844 | RAPGEF6, ACTG1, CLDN5, ARHGEF2, CTTN, MYL9 | More | | Pentagastrin | hsa04610 | Complement and coagulation cascades | 2.94E-02 | 2 | P25116, P10909 | F2R, CLU | More | | Pentagastrin | hsa04611 | Platelet activation | 1.59E-05 | 5 | P25116, P08514, Q15746, Q8WYR1, P07359 | F2R, ITGA2B, MYLK, PIK3R5, GP1BA | More | | Pentagastrin | hsa04613 | Neutrophil extracellular trap formation | 2.81E-04 | 18 | P17252, O60603, P05164, P08246, Q9UM07, P04908, Q6FI13, Q93077, P68431, P14598, Q15080, P20160, P08311, P49913, P21730, P21462, O43315, Q16539 | PRKCA, TLR2, MPO, ELA2, PADI4, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, C5AR1, FPR1, AQP9, MAPK14 | More | | Pentagastrin | hsa04621 | NOD-like receptor signaling pathway | 3.10E-03 | 11 | Q14643, P25963, Q13489, Q9H1Y0, P43490, O00463, P10415, Q05823, P01375, P49913, P12838 | ITPR1, NFKBIA, BIRC3, ATG5, PBEF1, TRAF5, BCL2, RNASEL, TNF, CAMP, DEFA4 | More | | Pentagastrin | hsa04650 | Natural killer cell mediated cytotoxicity | 2.95E-02 | 7 | P06239, P20963, Q13241, P26718, O14931, P26717, P26715 | LCK, CD247, KLRD1, KLRK1, NCR3, KLRC2, KLRC1 | More | | Pentagastrin | hsa04658 | Th1 and Th2 cell differentiation | 1.26E-04 | 9 | P07766, P20963, P09693, Q16539, P01730, P06239, P23771, Q9UL17, Q13761 | CD3E, CD247, CD3G, MAPK14, CD4, LCK, GATA3, TBX21, RUNX3 | More | | Pentagastrin | hsa04659 | Th17 cell differentiation | 2.95E-04 | 11 | Q16539, P19174, P01730, P06239, P14784, P14778, P23771, P84022, Q13485, P08238, P07766 | MAPK14, PLCG1, CD4, LCK, IL2RB, IL1R1, GATA3, SMAD3, SMAD4, HSP90AB1, CD3E | More | | Pentagastrin | hsa04660 | T cell receptor signaling pathway | 1.37E-03 | 13 | P01375, P25963, Q9UDY8, Q04759, P10747, O95267, Q08881, P07766, P20963, P09693, P01732, Q13191, P06239 | TNF, NFKBIA, MALT1, PRKCQ, CD28, RASGRP1, ITK, CD3E, CD247, CD3G, CD8A, CBLB, LCK | More | | Pentagastrin | hsa04662 | B cell receptor signaling pathway | 1.74E-02 | 5 | P42338, P60033, P07948, P21854, Q8N149 | PIK3CB, CD81, LYN, CD72, LILRA2 | More | | Pentagastrin | hsa04664 | Fc epsilon RI signaling pathway | 2.47E-02 | 4 | P42338, P07948, P19174, P09917 | PIK3CB, LYN, PLCG1, ALOX5 | More | | Pentagastrin | hsa04668 | TNF signaling pathway | 2.59E-02 | 7 | P01375, O00463, Q13489, P25963, P20749, Q13077, P14780 | TNF, TRAF5, BIRC3, NFKBIA, BCL3, TRAF1, MMP9 | More | | Pentagastrin | hsa04670 | Leukocyte transendothelial migration | 4.20E-02 | 7 | P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681 | MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXK | More | | Pentagastrin | hsa04714 | Thermogenesis | 5.21E-03 | 4 | Q16539, P33121, Q16718, O14521 | MAPK14, ACSL1, NDUFA5, SDHD | More | | Pentagastrin | hsa04722 | Neurotrophin signaling pathway | 2.78E-03 | 4 | P49841, O43524, P48023, P04637 | GSK3B, FOXO3, FASLG, TP53 | More | | Pentagastrin | hsa04724 | Glutamatergic synapse | 2.94E-02 | 2 | P48058, Q9NSB8 | GRIA4, HOMER2 | More | | Pentagastrin | hsa04810 | Regulation of actin cytoskeleton | 1.38E-03 | 4 | P24844, Q15746, P08514, P25116 | MYL9, MYLK, ITGA2B, F2R | More | | Pentagastrin | hsa04919 | Thyroid hormone signaling pathway | 3.71E-02 | 2 | P26678, P08237 | PLN, PFKM | More | | Pentagastrin | hsa04920 | Adipocytokine signaling pathway | 4.49E-02 | 4 | P25963, P33121, Q04759, P01375 | NFKBIA, ACSL1, PRKCQ, TNF | More | | Pentagastrin | hsa04921 | Oxytocin signaling pathway | 6.37E-03 | 3 | Q15746, P24844, Q8WYR1 | MYLK, MYL9, PIK3R5 | More | | Pentagastrin | hsa04932 | Non-alcoholic fatty liver disease | 2.21E-04 | 6 | P01375, P49841, Q14790, P48023, Q16718, O14521 | TNF, GSK3B, CASP8, FASLG, NDUFA5, SDHD | More | | Pentagastrin | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 3.21E-02 | 5 | P84022, Q13485, P42338, P49767, P19174 | SMAD3, SMAD4, PIK3CB, VEGFC, PLCG1 | More | | Pentagastrin | hsa04940 | Type I diabetes mellitus | 1.87E-02 | 2 | P48023, P01375 | FASLG, TNF | More | | Pentagastrin | hsa04970 | Salivary secretion | 4.49E-02 | 4 | P22694, Q14643, P17252, P49913 | PRKACB, ITPR1, PRKCA, CAMP | More | | Pentagastrin | hsa04976 | Bile secretion | 3.32E-02 | 2 | O43315, P08183 | AQP9, ABCB1 | More | | Pentagastrin | hsa05020 | Prion disease | 3.80E-02 | 4 | Q16718, O14521, P49841, Q16539 | NDUFA5, SDHD, GSK3B, MAPK14 | More | | Pentagastrin | hsa05022 | Pathways of neurodegeneration - multiple diseases | 1.24E-02 | 6 | P49841, Q16718, O14521, Q13561, Q16539, Q08752 | GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPID | More | | Pentagastrin | hsa05130 | Pathogenic Escherichia coli infection | 2.51E-02 | 3 | Q14247, O00501, P25116 | CTTN, CLDN5, F2R | More | | Pentagastrin | hsa05131 | Shigellosis | 3.34E-02 | 11 | P01375, P25963, O00463, Q04759, Q9UDY8, Q9H1Y0, Q14643, Q12778, Q13315, P10415, Q96A32 | TNF, NFKBIA, TRAF5, PRKCQ, MALT1, ATG5, ITPR1, FOXO1, ATM, BCL2, MYLPF | More | | Pentagastrin | hsa05132 | Salmonella infection | 2.98E-02 | 11 | P51617, P25963, P01375, Q9UJU2, Q13489, P10415, Q96A32, O60603, Q9BQS8, Q13561, Q13509 | IRAK1, NFKBIA, TNF, LEF1, BIRC3, BCL2, MYLPF, TLR2, FYCO1, DCTN2, TUBB3 | More | | Pentagastrin | hsa05140 | Leishmaniasis | 1.18E-02 | 7 | P14598, P13765, O60603, P25963, P01375, P51617, Q15080 | NCF1, HLA-DOB, TLR2, NFKBIA, TNF, IRAK1, NCF4 | More | | Pentagastrin | hsa05142 | Chagas disease | 2.37E-02 | 2 | P48023, Q14790 | FASLG, CASP8 | More | | Pentagastrin | hsa05143 | African trypanosomiasis | 2.72E-02 | 2 | P01375, P48023 | TNF, FASLG | More | | Pentagastrin | hsa05145 | Toxoplasmosis | 3.07E-02 | 7 | P51617, P25963, P01375, P10415, Q13489, P13765, O60603 | IRAK1, NFKBIA, TNF, BCL2, BIRC3, HLA-DOB, TLR2 | More | | Pentagastrin | hsa05152 | Tuberculosis | 2.07E-02 | 9 | Q13488, P48382, O60603, P01375, P10415, P13765, P49913, Q9UDY8, P51617 | TCIRG1, RFX5, TLR2, TNF, BCL2, HLA-DOB, CAMP, MALT1, IRAK1 | More | | Pentagastrin | hsa05160 | Hepatitis C | 2.45E-04 | 6 | P60033, P49841, P04637, P01375, P48023, Q14790 | CD81, GSK3B, TP53, TNF, FASLG, CASP8 | More | | Pentagastrin | hsa05161 | Hepatitis B | 2.63E-03 | 11 | P17252, P14780, P25963, P01375, P10415, P48023, Q14790, P04637, P51617, O60603, Q14765 | PRKCA, MMP9, NFKBIA, TNF, BCL2, FASLG, CASP8, TP53, IRAK1, TLR2, STAT4 | More | | Pentagastrin | hsa05162 | Measles | 8.19E-03 | 3 | P48023, P04637, Q14790 | FASLG, TP53, CASP8 | More | | Pentagastrin | hsa05163 | Human cytomegalovirus infection | 1.02E-02 | 3 | P48023, Q14790, P04637 | FASLG, CASP8, TP53 | More | | Pentagastrin | hsa05164 | Influenza A | 4.65E-02 | 2 | P48023, Q14790 | FASLG, CASP8 | More | | Pentagastrin | hsa05165 | Human papillomavirus infection | 2.62E-02 | 3 | P48023, P04637, Q14790 | FASLG, TP53, CASP8 | More | | Pentagastrin | hsa05170 | Human immunodeficiency virus 1 infection | 1.06E-03 | 13 | P01375, P17252, O00463, Q14643, P51617, P25963, O60603, Q13315, O95067, P10415, Q13619, Q93034, Q9Y6Q5 | TNF, PRKCA, TRAF5, ITPR1, IRAK1, NFKBIA, TLR2, ATM, CCNB2, BCL2, CUL4A, CUL5, AP1M2 | More | | Pentagastrin | hsa05200 | Pathways in cancer | 9.46E-03 | 17 | Q13751, P42338, P08238, P19174, P43246, P84022, Q13485, Q13547, P30281, P49767, P43657, P63218, P50151, Q14344, Q7LDG7, O75293, P14784 | LAMB3, PIK3CB, HSP90AB1, PLCG1, MSH2, SMAD3, SMAD4, HDAC1, CCND3, VEGFC, P2RY5, GNG5, GNG10, GNA13, RASGRP2, GADD45B, IL2RB | More | | Pentagastrin | hsa05202 | Transcriptional misregulation in cancer | 1.51E-04 | 14 | Q12778, Q15532, Q13315, P14780, P14923, Q16548, Q13489, Q13077, P35226, P05164, P12838, P08246, Q9C0K0, P24522 | FOXO1, SS18, ATM, MMP9, JUP, BCL2A1, BIRC3, TRAF1, BMI1, MPO, DEFA4, ELA2, BCL11B, GADD45A | More | | Pentagastrin | hsa05212 | Pancreatic cancer | 3.94E-02 | 4 | P42338, P84022, Q13485, O75293 | PIK3CB, SMAD3, SMAD4, GADD45B | More | | Pentagastrin | hsa05220 | Chronic myeloid leukemia | 2.16E-02 | 5 | Q13547, Q13485, P84022, P42338, O75293 | HDAC1, SMAD4, SMAD3, PIK3CB, GADD45B | More | | Pentagastrin | hsa05222 | Small cell lung cancer | 2.79E-02 | 6 | Q13489, P10415, P25963, Q13077, O00463, P24522 | BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45A | More | | Pentagastrin | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 4.02E-02 | 4 | P07766, P06239, Q16539, P01730 | CD3E, LCK, MAPK14, CD4 | More | | Pentagastrin | hsa05310 | Asthma | 3.88E-02 | 3 | P13765, P12724, P01375 | HLA-DOB, RNASE3, TNF | More | | Pentagastrin | hsa05321 | Inflammatory bowel disease | 1.28E-02 | 5 | O60603, P01375, P13765, Q14765, P23771 | TLR2, TNF, HLA-DOB, STAT4, GATA3 | More | | Pentagastrin | hsa05322 | Systemic lupus erythematosus | 4.20E-02 | 7 | P08246, P08311, P01375, P10747, P13765, Q6FI13, P05455 | ELA2, CTSG, TNF, CD28, HLA-DOB, H2AC18; H2AC19, SSB | More | | Pentagastrin | hsa05330 | Allograft rejection | 2.72E-02 | 2 | P48023, P01375 | FASLG, TNF | More | | Pentagastrin | hsa05332 | Graft-versus-host disease | 8.44E-04 | 6 | P13765, P48023, P10747, P01375, P26715, Q13241 | HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1 | More | | Pentagastrin | hsa05340 | Primary immunodeficiency | 5.29E-04 | 5 | P01730, P11912, P16871, P07766, P06239 | CD4, CD79A, IL7R, CD3E, LCK | More | | Pentagastrin | hsa05415 | Diabetic cardiomyopathy | 1.28E-02 | 4 | Q16718, O14521, Q16539, P49841 | NDUFA5, SDHD, MAPK14, GSK3B | More | | |