PharmaCoNets of Palmitic-acid (SPCN: 30.44 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Palmitic-Acidhsa00520Amino sugar and nucleotide sugar metabolism7.87E-033Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Palmitic-Acidhsa00533Glycosaminoglycan biosynthesis - keratan sulfate3.43E-021Q9NY97B3GNT2More
Palmitic-Acidhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Palmitic-Acidhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Palmitic-Acidhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series4.30E-032P06865, O75752HEXA, B3GALNT1More
Palmitic-Acidhsa00630Glyoxylate and dicarboxylate metabolism4.46E-032P40925, P15104MDH1, GLULMore
Palmitic-Acidhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-032P78417, P11712GSTO1, CYP2C9More
Palmitic-Acidhsa00982Drug metabolism - cytochrome P4509.14E-032P11712, P78417CYP2C9, GSTO1More
Palmitic-Acidhsa01200Carbon metabolism4.06E-025P37837, O14521, P50213, P60891, Q02252TALDO1, SDHD, IDH3A, PRPS1, ALDH6A1More
Palmitic-Acidhsa01523Antifolate resistance2.04E-022P04818, P18054TYMS, ALOX12More
Palmitic-Acidhsa03013RNA transport4.73E-0415P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q7Z3B4, P35658, P63279, Q14152, P55884, O15371, O75822, P20042, Q9Y6A5NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, NUP54, NUP214, UBE2I, EIF3A, EIF3B, EIF3D, EIF3J, EIF2S2, TACC3More
Palmitic-Acidhsa03015mRNA surveillance pathway4.42E-024O60942, O43148, P52298, Q53GS7RNGTT, RNMT, NCBP2, GLE1More
Palmitic-Acidhsa03040Spliceosome3.23E-039O60508, P08579, Q15427, P38159, P61978, Q07955, Q01130, P11142, Q9Y2W2CDC40, SNRPB2, SF3B4, RBMX, HNRPK, SFRS1, SFRS2, HSPA8, WBP11More
Palmitic-Acidhsa03060Protein export1.43E-022P37108, Q15005SRP14, SPCS2More
Palmitic-Acidhsa03320PPAR signaling pathway4.24E-034Q6PCB7, O00767, Q9UNU6, Q02318SLC27A1, SCD, CYP8B1, CYP27A1More
Palmitic-Acidhsa04012ErbB signaling pathway3.74E-023P21860, Q13557, O14944ERBB3, CAMK2D, EREGMore
Palmitic-Acidhsa04014Ras signaling pathway2.54E-025P42338, P20827, P49767, Q13009, P50151PIK3CB, EFNA1, VEGFC, TIAM1, GNG10More
Palmitic-Acidhsa04020Calcium signaling pathway6.50E-046Q96DU7, P45880, Q13557, P21860, P51828, P23634ITPKC, VDAC2, CAMK2D, ERBB3, ADCY7, ATP2B4More
Palmitic-Acidhsa04022cGMP-PKG signaling pathway4.72E-024Q99941, P23634, P51828, P45880CREBL1, ATP2B4, ADCY7, VDAC2More
Palmitic-Acidhsa04061Viral protein interaction with cytokine and cytokine receptor3.02E-023P09341, P02775, Q13651CXCL1, PPBP, IL10RAMore
Palmitic-Acidhsa04114Oocyte meiosis1.62E-045Q9Y6D9, P51812, Q02750, P16298, Q17RY0MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Palmitic-Acidhsa04141Protein processing in endoplasmic reticulum3.64E-025Q99941, O75460, P11142, Q9H3Z4, P07900CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1More
Palmitic-Acidhsa04145Phagosome2.61E-025P63261, Q15080, P14598, Q13509, P68371ACTG1, NCF4, NCF1, TUBB3, TUBB2CMore
Palmitic-Acidhsa04150mTOR signaling pathway3.60E-023Q02750, Q9NQL2, P51812MAP2K1, RRAGD, RPS6KA3More
Palmitic-Acidhsa04151PI3K-Akt signaling pathway1.14E-028P42338, P43657, P20827, P49767, P50151, O15335, Q13751, P14784PIK3CB, P2RY5, EFNA1, VEGFC, GNG10, CHAD, LAMB3, IL2RBMore
Palmitic-Acidhsa04211Longevity regulating pathway3.63E-023Q08828, Q99941, Q96RR4ADCY1, CREBL1, CAMKK2More
Palmitic-Acidhsa04215Apoptosis - multiple species1.56E-022Q13489, P10415BIRC3, BCL2More
Palmitic-Acidhsa04217Necroptosis5.89E-037P01568, Q13489, Q13546, P07384, Q6FI13, P10415, O43633IFNA21, BIRC3, RIPK1, CAPN1, H2AC18; H2AC19, BCL2, CHMP2AMore
Palmitic-Acidhsa04261Adrenergic signaling in cardiomyocytes3.98E-024P51828, Q99941, Q13557, P23634ADCY7, CREBL1, CAMK2D, ATP2B4More
Palmitic-Acidhsa04270Vascular smooth muscle contraction8.93E-034P0DP24, Q08828, P35579, P35318CALM2, ADCY1, MYH9, ADMMore
Palmitic-Acidhsa04330Notch signaling pathway4.34E-022Q92542, P46531NCSTN, NOTCH1More
Palmitic-Acidhsa04370VEGF signaling pathway1.43E-053P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Palmitic-Acidhsa04390Hippo signaling pathway2.08E-023P84022, Q13485, Q13489SMAD3, SMAD4, BIRC3More
Palmitic-Acidhsa04510Focal adhesion4.64E-026O75369, Q15942, Q13489, P10415, P49767, P63261FLNB, ZYX, BIRC3, BCL2, VEGFC, ACTG1More
Palmitic-Acidhsa04530Tight junction2.45E-036Q8TEU7, P16989, P56750, O00501, Q14247, P24844RAPGEF6, CSDA, CLDN17, CLDN5, CTTN, MYL9More
Palmitic-Acidhsa04613Neutrophil extracellular trap formation8.99E-0417P17252, O60603, P08246, Q9UM07, Q92769, Q6FI13, Q93077, P62807, O60814, P68431, P14598, Q15080, O75015, P21730, P21462, O43315, Q16539PRKCA, TLR2, ELA2, PADI4, HDAC2, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Palmitic-Acidhsa04623Cytosolic DNA-sensing pathway2.46E-022P01568, Q13546IFNA21, RIPK1More
Palmitic-Acidhsa04650Natural killer cell mediated cytotoxicity2.21E-033P16298, P50591, Q02750PPP3CB, TNFSF10, MAP2K1More
Palmitic-Acidhsa04659Th17 cell differentiation3.17E-023P25963, P84022, Q13485NFKBIA, SMAD3, SMAD4More
Palmitic-Acidhsa04662B cell receptor signaling pathway9.78E-045P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Palmitic-Acidhsa04664Fc epsilon RI signaling pathway1.82E-023P42338, P07948, P09917PIK3CB, LYN, ALOX5More
Palmitic-Acidhsa04668TNF signaling pathway4.74E-023Q99941, P01584, O95429CREBL1, IL1B, BAG4More
Palmitic-Acidhsa04710Circadian rhythm1.67E-022Q16526, Q9Y478CRY1, PRKAB1More
Palmitic-Acidhsa04720Long-term potentiation7.72E-043P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Palmitic-Acidhsa04724Glutamatergic synapse3.24E-023P43003, P50151, P15104SLC1A3, GNG10, GLULMore
Palmitic-Acidhsa04750Inflammatory mediator regulation of TRP channels3.74E-023P01584, P51828, Q13557IL1B, ADCY7, CAMK2DMore
Palmitic-Acidhsa04911Insulin secretion1.48E-023P51828, Q99941, Q13557ADCY7, CREBL1, CAMK2DMore
Palmitic-Acidhsa04912GnRH signaling pathway3.39E-024P17252, Q16539, Q9Y6R4, Q14643PRKCA, MAPK14, MAP3K4, ITPR1More
Palmitic-Acidhsa04914Progesterone-mediated oocyte maturation5.67E-044Q17RY0, Q9Y6D9, P51812, Q02750CPEB4, MAD1L1, RPS6KA3, MAP2K1More
Palmitic-Acidhsa04915Estrogen signaling pathway4.72E-024Q99941, P51828, P07900, P11142CREBL1, ADCY7, HSP90AA1, HSPA8More
Palmitic-Acidhsa04920Adipocytokine signaling pathway4.31E-022Q9Y478, Q96RR4PRKAB1, CAMKK2More
Palmitic-Acidhsa04925Aldosterone synthesis and secretion3.02E-046Q99941, Q08828, P51828, P0DP24, Q13557, P23634CREBL1, ADCY1, ADCY7, CALM2, CAMK2D, ATP2B4More
Palmitic-Acidhsa04933AGE-RAGE signaling pathway in diabetic complications1.25E-023P84022, Q13485, P10415SMAD3, SMAD4, BCL2More
Palmitic-Acidhsa04934Cushing syndrome3.48E-034Q99941, P51828, O15169, Q13557CREBL1, ADCY7, AXIN1, CAMK2DMore
Palmitic-Acidhsa04971Gastric acid secretion1.48E-023P51828, P15311, Q13557ADCY7, VIL2, CAMK2DMore
Palmitic-Acidhsa04972Pancreatic secretion3.86E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Palmitic-Acidhsa04975Fat digestion and absorption3.43E-021O14494PLPP1More
Palmitic-Acidhsa05010Alzheimer disease2.07E-027Q92542, P05496, P12074, O75460, P01584, O15169, P45880NCSTN, ATP5G1, COX6A1, ERN1, IL1B, AXIN1, VDAC2More
Palmitic-Acidhsa05020Prion disease1.81E-027P01584, P46531, P11142, P05496, P12074, P45880, Q99941IL1B, NOTCH1, HSPA8, ATP5G1, COX6A1, VDAC2, CREBL1More
Palmitic-Acidhsa05022Pathways of neurodegeneration - multiple diseases2.69E-028O15399, Q13509, P68371, P10415, Q13561, P07384, P04628, P0DP23GRIN2D, TUBB3, TUBB2C, BCL2, DCTN2, CAPN1, WNT1, CALM1More
Palmitic-Acidhsa05034Alcoholism2.89E-034Q93077, P62807, O60814, P68431HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Palmitic-Acidhsa05132Salmonella infection5.02E-0410P25963, P63261, Q13546, Q13489, P10415, O75369, Q9BQS8, Q13561, Q13509, P68371NFKBIA, ACTG1, RIPK1, BIRC3, BCL2, FLNB, FYCO1, DCTN2, TUBB3, TUBB2CMore
Palmitic-Acidhsa05135Yersinia infection2.58E-024Q05397, P51812, Q02750, Q96JJ3PTK2, RPS6KA3, MAP2K1, ELMO2More
Palmitic-Acidhsa05145Toxoplasmosis2.78E-023P25963, P10415, Q13489NFKBIA, BCL2, BIRC3More
Palmitic-Acidhsa05160Hepatitis C4.55E-023O00501, P29728, P01106CLDN5, OAS2, MYCMore
Palmitic-Acidhsa05161Hepatitis B8.49E-034P25963, Q13485, P10415, P84022NFKBIA, SMAD4, BCL2, SMAD3More
Palmitic-Acidhsa05163Human cytomegalovirus infection3.04E-025P0DP24, Q08828, P23458, P61073, Q99941CALM2, ADCY1, JAK1, CXCR4, CREBL1More
Palmitic-Acidhsa05167Kaposi sarcoma-associated herpesvirus infection1.94E-024P62879, P16298, Q02750, P0CG47GNB2, PPP3CB, MAP2K1, UBBMore
Palmitic-Acidhsa05168Herpes simplex virus 1 infection1.17E-0210Q9UKJ0, Q06124, P01568, Q01130, Q13489, Q13398, Q9NR11, Q03923, Q9UDV6, P10415PILRB, PTPN11, IFNA21, SFRS2, BIRC3, ZNF211, ZNF302, ZNF85, ZNF212, BCL2More
Palmitic-Acidhsa05170Human immunodeficiency virus 1 infection8.23E-045Q02750, P62879, P16298, Q05397, P20333MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1BMore
Palmitic-Acidhsa05203Viral carcinogenesis4.85E-023Q15283, P62807, O60814RASA2, HIST1H2BC, H2BC12More
Palmitic-Acidhsa05204Chemical carcinogenesis1.48E-022P78417, P11712GSTO1, CYP2C9More
Palmitic-Acidhsa05206MicroRNAs in cancer2.97E-036P15311, P21860, P61978, P46531, P63279, P22105VIL2, ERBB3, HNRPK, NOTCH1, UBE2I, TNXBMore
Palmitic-Acidhsa05210Colorectal cancer1.78E-023P84022, Q13485, P10415SMAD3, SMAD4, BCL2More
Palmitic-Acidhsa05212Pancreatic cancer3.52E-022P84022, Q13485SMAD3, SMAD4More
Palmitic-Acidhsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Palmitic-Acidhsa05220Chronic myeloid leukemia1.25E-023Q13485, P25963, P84022SMAD4, NFKBIA, SMAD3More
Palmitic-Acidhsa05222Small cell lung cancer3.77E-037P10826, Q13489, P10415, P25963, Q13077, O00463, P24522RARB, BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45AMore
Palmitic-Acidhsa05226Gastric cancer4.33E-035Q02750, O15169, P84022, Q13485, P10415MAP2K1, AXIN1, SMAD3, SMAD4, BCL2More
Palmitic-Acidhsa05322Systemic lupus erythematosus1.31E-045P09871, Q93077, P62807, O60814, P68431C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Palmitic-Acidhsa05415Diabetic cardiomyopathy3.19E-027P17252, P14598, Q15080, Q16718, O14521, Q16539, P14780PRKCA, NCF1, NCF4, NDUFA5, SDHD, MAPK14, MMP9More

Community members of Palmitic-acid (SDC: 2.85)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)