PharmaCoNets of Ondansetron (SPCN: 246.84 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Ondansetronhsa00030Pentose phosphate pathway5.43E-094P60891, P51854, P52209, P37837PRPS1, TKTL1, PGD, TALDO1More
Ondansetronhsa00040Pentose and glucuronate interconversions3.53E-021O60701UGDHMore
Ondansetronhsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Ondansetronhsa00071Fatty acid degradation3.65E-034O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Ondansetronhsa00190Oxidative phosphorylation5.12E-043Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
Ondansetronhsa00220Arginine biosynthesis3.11E-063P15104, P05089, P49448GLUL, ARG1, GLUD2More
Ondansetronhsa00240Pyrimidine metabolism3.59E-032P31350, P04818RRM2, TYMSMore
Ondansetronhsa00310Lysine degradation4.09E-053Q96KQ7, Q02809, P51648EHMT2, PLOD1, ALDH3A2More
Ondansetronhsa00340Histidine metabolism4.52E-021O95954FTCDMore
Ondansetronhsa00410beta-Alanine metabolism3.98E-021Q6ZQY3GADL1More
Ondansetronhsa00471D-Glutamine and D-glutamate metabolism3.98E-021Q7Z3D6C14orf159More
Ondansetronhsa00500Starch and sucrose metabolism9.11E-124O43451, P46976, P35573, P06737MGAM, GYG1, AGL, PYGLMore
Ondansetronhsa00510N-Glycan biosynthesis3.15E-022P15907, Q9NR34ST6GAL1, MAN1C1More
Ondansetronhsa00512Mucin type O-glycan biosynthesis3.19E-033O95395, Q8N4A0, Q9NY28GCNT3, GALNT4, GALNT8More
Ondansetronhsa00520Amino sugar and nucleotide sugar metabolism2.11E-023Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Ondansetronhsa00532Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate3.68E-021Q9Y2C2USTMore
Ondansetronhsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.91E-021Q9NY97B3GNT2More
Ondansetronhsa00562Inositol phosphate metabolism2.00E-024P27987, P19174, P42338, Q02252ITPKB, PLCG1, PIK3CB, ALDH6A1More
Ondansetronhsa00564Glycerophospholipid metabolism9.70E-032Q9Y259, P49619CHKB, DGKGMore
Ondansetronhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Ondansetronhsa00591Linoleic acid metabolism4.84E-051P11712CYP2C9More
Ondansetronhsa00600Sphingolipid metabolism3.76E-021P15289ARSAMore
Ondansetronhsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Ondansetronhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series8.72E-032P06865, O75752HEXA, B3GALNT1More
Ondansetronhsa00604Glycosphingolipid biosynthesis - ganglio series2.46E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Ondansetronhsa00630Glyoxylate and dicarboxylate metabolism3.85E-093P40925, P40926, P15104MDH1, MDH2, GLULMore
Ondansetronhsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Ondansetronhsa00670One carbon pool by folate9.61E-053O95954, P04818, Q99707FTCD, TYMS, MTRMore
Ondansetronhsa00730Thiamine metabolism2.62E-063Q9Y6K8, P05186, P24666AK5, ALPL, ACP1More
Ondansetronhsa00770Pantothenate and CoA biosynthesis3.60E-074O95498, O95497, Q6ZQY3, Q9NRN7VNN2, VNN1, GADL1, AASDHPPTMore
Ondansetronhsa00790Folate biosynthesis1.22E-022P05186, P42330ALPL, AKR1C3More
Ondansetronhsa00830Retinol metabolism1.21E-055P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Ondansetronhsa00860Porphyrin and chlorophyll metabolism1.20E-043P36551, P53004, P30043CPOX, BLVRA, BLVRBMore
Ondansetronhsa00900Terpenoid backbone biosynthesis3.05E-021Q01581HMGCS1More
Ondansetronhsa00970Aminoacyl-tRNA biosynthesis3.15E-104O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Ondansetronhsa00980Metabolism of xenobiotics by cytochrome P4501.04E-042P78417, P11712GSTO1, CYP2C9More
Ondansetronhsa00982Drug metabolism - cytochrome P4501.04E-042P11712, P78417CYP2C9, GSTO1More
Ondansetronhsa00983Drug metabolism - other enzymes1.86E-034P04183, P20839, P32320, P05164TK1, IMPDH1, CDA, MPOMore
Ondansetronhsa01100Metabolic pathways6.99E-0330Q9NR34, Q9Y259, P05089, P32320, Q13956, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, P49619, O95954, Q9HCC0, P33121, Q02318, P57054, Q9UBX8, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P35573, P06737MAN1C1, CHKB, ARG1, CDA, PDE6H, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, DGKG, FTCD, MCCC2, ACSL1, CYP27A1, PIGP, B4GALT6, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, AGL, PYGLMore
Ondansetronhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Ondansetronhsa012102-Oxocarboxylic acid metabolism2.63E-041P50213IDH3AMore
Ondansetronhsa01230Biosynthesis of amino acids1.42E-045P51854, P60891, Q99707, P05089, P37837TKTL1, PRPS1, MTR, ARG1, TALDO1More
Ondansetronhsa01240Biosynthesis of cofactors1.34E-034P13716, P36551, O60701, P14618ALAD, CPOX, UGDH, PKM2More
Ondansetronhsa01521EGFR tyrosine kinase inhibitor resistance5.65E-044P49841, P42338, P04049, P08069GSK3B, PIK3CB, RAF1, IGF1RMore
Ondansetronhsa01522Endocrine resistance4.47E-042P04049, P08069RAF1, IGF1RMore
Ondansetronhsa01523Antifolate resistance1.43E-032Q92820, P04818GGH, TYMSMore
Ondansetronhsa01524Platinum drug resistance4.78E-021P31751AKT2More
Ondansetronhsa02010ABC transporters1.98E-033P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Ondansetronhsa03008Ribosome biogenesis in eukaryotes8.13E-056Q9NYH9, O14980, O60832, P78345, Q9BVP2, Q9GZY0UTP6, XPO1, DKC1, RPP38, GNL3, NXF2; NXF2BMore
Ondansetronhsa03010Ribosome5.71E-0814P62753, P62906, P62829, P46776, P46777, Q07020, Q9UHA3, P62888, P61927, P61513, P36578, P27635, P62249, P23396RPS6, RPL10A, RPL23, RPL27A, RPL5, RPL18, RSL24D1, RPL30, RPL37, RPL37A, RPL4, RPL10, RPS16, RPS3More
Ondansetronhsa03013RNA transport6.02E-1527P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q9GZY0, Q9H307, Q7Z3B4, P35658, P63279, P68104, Q14152, P55884, O15371, O75822, P78345, P20042, Q14240, P23588, Q9Y6A5, Q14232, Q06787, P51114, Q53GS7RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, NXF2; NXF2B, PNN, NUP54, NUP214, UBE2I, EEF1A1, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, EIF2S2, EIF4A2, EIF4B, TACC3, EIF2B1, FMR1, FXR1, GLE1More
Ondansetronhsa03015mRNA surveillance pathway8.18E-049O43148, Q13362, Q14738, Q16537, P61326, Q9UBU9, Q9GZY0, P52298, Q53GS7RNMT, PPP2R5C, PPP2R5D, PPP2R5E, MAGOH, NXF1, NXF2; NXF2B, NCBP2, GLE1More
Ondansetronhsa03020RNA polymerase8.28E-126P30876, P24928, P62487, Q9GZM3, P52435, Q9Y535POLR2B, POLR2A, POLR2G, POLR2J2, POLR2J, POLR3HMore
Ondansetronhsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Ondansetronhsa03040Spliceosome1.60E-1219Q14562, O43143, O60508, P17844, P08579, Q15427, P26368, P51991, P38159, P61978, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, DDX5, SNRPB2, SF3B4, U2AF2, HNRPA3, RBMX, HNRPK, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Ondansetronhsa03050Proteasome2.87E-042P55036, P62195PSMD4, PSMC5More
Ondansetronhsa03060Protein export1.20E-032P37108, Q15005SRP14, SPCS2More
Ondansetronhsa03320PPAR signaling pathway2.42E-034Q6PCB7, Q9UNU6, Q13133, Q02318SLC27A1, CYP8B1, NR1H3, CYP27A1More
Ondansetronhsa03430Mismatch repair4.38E-021P20585MSH3More
Ondansetronhsa03450Non-homologous end-joining4.21E-021P13010XRCC5More
Ondansetronhsa04010MAPK signaling pathway1.69E-032P04049, P08069RAF1, IGF1RMore
Ondansetronhsa04012ErbB signaling pathway5.99E-0710P21860, P49841, P16333, P17252, Q13557, P19174, O14944, P42338, P01106, P04049ERBB3, GSK3B, NCK1, PRKCA, CAMK2D, PLCG1, EREG, PIK3CB, MYC, RAF1More
Ondansetronhsa04014Ras signaling pathway1.48E-0716P04049, P31751, P42338, P20827, Q9NRA1, P49767, P08069, Q13009, P17252, P14921, Q7LDG7, P0DP23, P62873, P63218, P50151, P19174RAF1, AKT2, PIK3CB, EFNA1, PDGFC, VEGFC, IGF1R, TIAM1, PRKCA, ETS1, RASGRP2, CALM1, GNB1, GNG5, GNG10, PLCG1More
Ondansetronhsa04015Rap1 signaling pathway1.22E-0615P04049, P20827, P49767, P08069, P06213, Q96FS4, P11215, Q13009, O00522, Q7LDG7, P42338, P31751, P0DP23, P17252, P19174RAF1, EFNA1, VEGFC, IGF1R, INSR, SIPA1, ITGAM, TIAM1, KRIT1, RASGRP2, PIK3CB, AKT2, CALM1, PRKCA, PLCG1More
Ondansetronhsa04020Calcium signaling pathway3.50E-0514P27987, Q96DU7, Q08828, P45880, Q13557, P17252, P21860, O15399, P19174, P0DP23, P05141, P51828, P23634, P49767ITPKB, ITPKC, ADCY1, VDAC2, CAMK2D, PRKCA, ERBB3, GRIN2D, PLCG1, CALM1, SLC25A5, ADCY7, ATP2B4, VEGFCMore
Ondansetronhsa04022cGMP-PKG signaling pathway1.31E-0612P04049, Q99941, P18848, P23634, Q8WYR1, P31751, Q08828, P51828, P05141, P45880, P0DP24, P0DP23RAF1, CREBL1, ATF4, ATP2B4, PIK3R5, AKT2, ADCY1, ADCY7, SLC25A5, VDAC2, CALM2, CALM1More
Ondansetronhsa04024cAMP signaling pathway1.97E-0510Q08828, P51828, P42338, P31751, P0DP23, P04049, Q13370, O15399, P25963, Q13009ADCY1, ADCY7, PIK3CB, AKT2, CALM1, RAF1, PDE3B, GRIN2D, NFKBIA, TIAM1More
Ondansetronhsa04060Cytokine-cytokine receptor interaction2.57E-0716P14784, P27930, P14778, P37173, P26842, Q06643, Q13651, P78552, P25024, P25025, Q9UBD3, P47992, O75509, P09341, P80075, P01730IL2RB, IL1R2, IL1R1, TGFBR2, CD27, LTB, IL10RA, IL13RA1, CXCR1, CXCR2, XCL2, XCL1, TNFRSF21, CXCL1, CCL8, CD4More
Ondansetronhsa04061Viral protein interaction with cytokine and cytokine receptor4.35E-0811Q8NHW4, P09341, P19875, P25024, P25025, P47992, Q9UBD3, Q13651, P14784, P09603, P01375CCL4L2, CXCL1, CXCL2, CXCR1, CXCR2, XCL1, XCL2, IL10RA, IL2RB, CSF1, TNFMore
Ondansetronhsa04062Chemokine signaling pathway8.46E-1325P25024, P25025, P09341, P19875, P47992, Q9UBD3, P09769, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q08881, Q7LDG7, Q13009, P14598, P22694, P42224, P04049, P25963, P49841, Q8WYR1CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, FGR, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, ITK, RASGRP2, TIAM1, NCF1, PRKACB, STAT1, RAF1, NFKBIA, GSK3B, PIK3R5More
Ondansetronhsa04064NF-kappa B signaling pathway1.96E-1725P10415, Q13489, P25963, P51617, O00463, Q13546, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, RIPK1, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, CYLDMore
Ondansetronhsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Ondansetronhsa04068FoxO signaling pathway3.80E-042P04049, P08069RAF1, IGF1RMore
Ondansetronhsa04070Phosphatidylinositol signaling system1.99E-0813P19174, P0DP23, Q14643, P42338, O14986, P23743, Q86XP1, Q16760, P48426, O14732, P27987, Q96DU7, P17252PLCG1, CALM1, ITPR1, PIK3CB, PIP5K1B, DGKA, DGKH, DGKD, PIP4K2A, IMPA2, ITPKB, ITPKC, PRKCAMore
Ondansetronhsa04071Sphingolipid signaling pathway2.26E-0710P04049, P17252, P21453, Q9H228, P01375, Q13362, Q16537, Q9BX95, P04637, P10415RAF1, PRKCA, S1PR1, EDG8, TNF, PPP2R5C, PPP2R5E, SGPP1, TP53, BCL2More
Ondansetronhsa04072Phospholipase D signaling pathway1.77E-0613P04049, P31751, P42338, Q9UQC2, P43657, P25024, P25025, P19174, O14986, Q15438, Q08828, P51828, Q16760RAF1, AKT2, PIK3CB, GAB2, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, PSCD1, ADCY1, ADCY7, DGKDMore
Ondansetronhsa04080Neuroactive ligand-receptor interaction6.78E-0614P08311, P28472, Q15722, P21453, Q9H228, P43657, O00398, Q01726, P41968, P21462, P21730, P14416, P07550, P35318CTSG, GABRB3, LTB4R, S1PR1, EDG8, P2RY5, P2RY10, MC1R, MC3R, FPR1, C5AR1, DRD2, ADRB2, ADMMore
Ondansetronhsa04110Cell cycle1.87E-0810Q9UBD5, P06493, O60566, Q14683, O75293, P30304, P33981, P42773, P01106, Q13547ORC3, CDK1, BUB1B, SMC1A, GADD45B, CDC25A, TTK, CDKN2C, MYC, HDAC1More
Ondansetronhsa04114Oocyte meiosis3.49E-0811Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738, P08069MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5D, IGF1RMore
Ondansetronhsa04115p53 signaling pathway6.79E-037P24522, Q13315, P31350, Q53FA7, P06493, O95067, P10415GADD45A, ATM, RRM2, TP53I3, CDK1, CCNB2, BCL2More
Ondansetronhsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Ondansetronhsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Ondansetronhsa04140Autophagy - animal8.63E-0514P08069, Q9Y4H2, P31751, P04049, Q7L523, Q9NQL2, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9IGF1R, IRS2, AKT2, RAF1, RRAGA, RRAGD, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Ondansetronhsa04141Protein processing in endoplasmic reticulum3.89E-0615P18848, P30101, Q15437, Q15436, P60604, Q99941, O75460, P11142, Q9H3Z4, P07900, P08238, Q9NR31, P14625, Q9H173, Q9UNL2ATF4, PDIA3, SEC23B, SEC23A, UBE2G2, CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1, HSP90AB1, SAR1A, HSP90B1, SIL1, SSR3More
Ondansetronhsa04142Lysosome1.46E-027P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2More
Ondansetronhsa04144Endocytosis2.89E-038P0DMV8, Q9H444, O75351, P62491, Q96B97, Q15438, Q14161, Q9UMY4HSPA1A, CHMP4B, VPS4B, RAB11A, SH3KBP1, PSCD1, GIT2, SNX12More
Ondansetronhsa04145Phagosome2.37E-0714O75015, P11215, P63261, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, P05164, P78380, O60603, P35443, P13765FCGR3B, ITGAM, ACTG1, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, MPO, OLR1, TLR2, THBS4, HLA-DOBMore
Ondansetronhsa04150mTOR signaling pathway1.58E-047P08069, P42338, P04049, Q02750, Q9NQL2, P51812, P49841IGF1R, PIK3CB, RAF1, MAP2K1, RRAGD, RPS6KA3, GSK3BMore
Ondansetronhsa04151PI3K-Akt signaling pathway7.23E-0829P62753, P42338, P43657, O43521, P27348, P20827, P49767, P07900, P08238, P14625, Q8WYR1, P62873, P63218, P50151, P16144, O15335, P02452, P24821, Q16363, Q13751, P22105, P14784, P01568, Q99941, P18848, P17252, O00141, Q6ZUJ8, P30281RPS6, PIK3CB, P2RY5, BCL2L11, YWHAQ, EFNA1, VEGFC, HSP90AA1, HSP90AB1, HSP90B1, PIK3R5, GNB1, GNG5, GNG10, ITGB4, CHAD, COL1A1, TNC, LAMA4, LAMB3, TNXB, IL2RB, IFNA21, CREBL1, ATF4, PRKCA, SGK, PIK3AP1, CCND3More
Ondansetronhsa04152AMPK signaling pathway2.37E-034P08069, Q96RR4, Q13362, Q14738IGF1R, CAMKK2, PPP2R5C, PPP2R5DMore
Ondansetronhsa04210Apoptosis3.11E-0413Q13315, P10415, Q13489, P25963, P01375, O75460, P24522, Q16548, Q13077, O43521, P18848, Q14643, P04049ATM, BCL2, BIRC3, NFKBIA, TNF, ERN1, GADD45A, BCL2A1, TRAF1, BCL2L11, ATF4, ITPR1, RAF1More
Ondansetronhsa04211Longevity regulating pathway3.68E-046P31751, P08069, Q08828, P51828, Q99941, P18848AKT2, IGF1R, ADCY1, ADCY7, CREBL1, ATF4More
Ondansetronhsa04213Longevity regulating pathway - multiple species1.48E-059P31751, P42338, P08069, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547AKT2, PIK3CB, IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Ondansetronhsa04217Necroptosis2.25E-0920P01375, P01568, P48023, Q13489, Q9NQC7, Q13546, P42224, Q14765, P07900, P08238, P15104, P05141, P01584, P0C0S5, Q6FI13, Q99878, Q93077, Q9H444, O43633, Q08752TNF, IFNA21, FASLG, BIRC3, CYLD, RIPK1, STAT1, STAT4, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, CHMP4B, CHMP2A, PPIDMore
Ondansetronhsa04218Cellular senescence3.00E-047P01106, P31751, P04049, O75293, P30304, P06493, P0DP23MYC, AKT2, RAF1, GADD45B, CDC25A, CDK1, CALM1More
Ondansetronhsa04261Adrenergic signaling in cardiomyocytes1.32E-0916P07550, Q08828, P51828, P22694, P31751, Q99941, P18848, Q13362, Q14738, Q16537, P0DP23, Q13557, P17252, P10415, P20020, P23634ADRB2, ADCY1, ADCY7, PRKACB, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, PPP2R5E, CALM1, CAMK2D, PRKCA, BCL2, ATP2B1, ATP2B4More
Ondansetronhsa04270Vascular smooth muscle contraction2.27E-037P0DP23, P04049, Q08828, P51828, P35579, P35749, P35318CALM1, RAF1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Ondansetronhsa04310Wnt signaling pathway1.79E-022P17612, P67870PRKACA, CSNK2BMore
Ondansetronhsa04330Notch signaling pathway4.34E-022Q92542, P46531NCSTN, NOTCH1More
Ondansetronhsa04340Hedgehog signaling pathway1.71E-046P49841, P17612, P22694, Q13635, P49407, P10415GSK3B, PRKACA, PRKACB, PTCH1, ARRB1, BCL2More
Ondansetronhsa04350TGF-beta signaling pathway4.88E-021P37173TGFBR2More
Ondansetronhsa04360Axon guidance1.36E-059P16333, P20827, O95631, P17252, P42338, P07332, P23528, P04049, P19174NCK1, EFNA1, NTN1, PRKCA, PIK3CB, FES, CFL1, RAF1, PLCG1More
Ondansetronhsa04370VEGF signaling pathway1.65E-098P19174, P16298, P31751, P42338, P17252, Q05397, Q02750, P04049PLCG1, PPP3CB, AKT2, PIK3CB, PRKCA, PTK2, MAP2K1, RAF1More
Ondansetronhsa04371Apelin signaling pathway1.97E-0714P62873, P63218, P50151, Q8WYR1, P31751, P04049, Q08828, P51828, Q13370, Q14814, Q14344, Q13485, P84022, P0DP23GNB1, GNG5, GNG10, PIK3R5, AKT2, RAF1, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, SMAD4, SMAD3, CALM1More
Ondansetronhsa04380Osteoclast differentiation1.32E-0815Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P42338, P31751, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, PIK3CB, AKT2, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Ondansetronhsa04390Hippo signaling pathway2.41E-034P63261, O15105, P04628, O43623ACTG1, SMAD7, WNT1, SNAI2More
Ondansetronhsa04510Focal adhesion1.16E-0413P16144, O75369, P42338, Q15942, P17252, O15335, Q13751, P51636, Q13489, P30281, P04049, P08069, P49767ITGB4, FLNB, PIK3CB, ZYX, PRKCA, CHAD, LAMB3, CAV2, BIRC3, CCND3, RAF1, IGF1R, VEGFCMore
Ondansetronhsa04512ECM-receptor interaction2.77E-056P02452, P24821, P07359, P26012, P08514, P16070COL1A1, TNC, GP1BA, ITGB8, ITGA2B, CD44More
Ondansetronhsa04520Adherens junction8.29E-031P08069IGF1RMore
Ondansetronhsa04530Tight junction3.60E-035P63261, P16989, P56750, Q92974, Q14247ACTG1, CSDA, CLDN17, ARHGEF2, CTTNMore
Ondansetronhsa04540Gap junction3.04E-047P17252, Q13509, P68371, Q71U36, P04049, Q9NRA1, Q14643PRKCA, TUBB3, TUBB2C, TUBA1A, RAF1, PDGFC, ITPR1More
Ondansetronhsa04550Signaling pathways regulating pluripotency of stem cells1.06E-047P04628, P40189, Q13873, P04049, Q02750, P08069, Q86SE9WNT1, IL6ST, BMPR2, RAF1, MAP2K1, IGF1R, PCGF5More
Ondansetronhsa04610Complement and coagulation cascades6.67E-043P09871, P0C0L4, P20023C1S, C4A, CR2More
Ondansetronhsa04611Platelet activation2.65E-056Q9Y490, P08514, Q15746, Q8WYR1, P17612, P07359TLN1, ITGA2B, MYLK, PIK3R5, PRKACA, GP1BAMore
Ondansetronhsa04612Antigen processing and presentation2.93E-1011P13765, P48382, P01730, Q14953, P26715, P26717, Q07444, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, CD4, KIR2DS5, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, TNFMore
Ondansetronhsa04613Neutrophil extracellular trap formation1.87E-1234P17252, P04049, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P04908, P0C0S5, Q6FI13, Q99878, Q93077, P58876, P62807, P33778, Q16778, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P63261, P07359, O43315, Q16539PRKCA, RAF1, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AC4; H2AC8, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, H2BC5, HIST1H2BC, H2BC3, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, ACTG1, GP1BA, AQP9, MAPK14More
Ondansetronhsa04614Renin-angiotensin system7.48E-034P50052, P15144, P08311, O75787AGTR2, ANPEP, CTSG, ATP6AP2More
Ondansetronhsa04620Toll-like receptor signaling pathway2.48E-055Q13546, P01568, P01584, P31751, Q8NHW4RIPK1, IFNA21, IL1B, AKT2, CCL4L2More
Ondansetronhsa04621NOD-like receptor signaling pathway9.29E-0720P01584, P07900, Q16539, Q14643, P21796, P25963, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, P29728, Q05823, P01375, P09341, P49913, P59665, P59666, P12838IL1B, HSP90AA1, MAPK14, ITPR1, VDAC1, NFKBIA, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, OAS2, RNASEL, TNF, CXCL1, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Ondansetronhsa04622RIG-I-like receptor signaling pathway1.88E-043P01568, Q9NQC7, Q13546IFNA21, CYLD, RIPK1More
Ondansetronhsa04623Cytosolic DNA-sensing pathway2.26E-116P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Ondansetronhsa04625C-type lectin receptor signaling pathway1.30E-0712Q9ULY5, P04049, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P31751, P0DP24, P0DP23, Q16539CLEC4E, RAF1, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, AKT2, CALM2, CALM1, MAPK14More
Ondansetronhsa04630JAK-STAT signaling pathway3.48E-047P31751, O75925, P23458, P40189, Q13651, Q06124, P04049AKT2, PIAS1, JAK1, IL6ST, IL10RA, PTPN11, RAF1More
Ondansetronhsa04640Hematopoietic cell lineage3.30E-1121P13612, P07359, P08514, P21926, P14778, P27930, P11215, P15144, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375, P09603, P01584ITGA4, GP1BA, ITGA2B, CD9, IL1R1, IL1R2, ITGAM, ANPEP, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF, CSF1, IL1BMore
Ondansetronhsa04650Natural killer cell mediated cytotoxicity1.63E-2419P16298, P50591, P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q02750, P04049, Q13241, P26718, O14931, O75015, P26717, Q07444, Q14953, P26715PPP3CB, TNFSF10, PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, RAF1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KIR2DS5, KLRC1More
Ondansetronhsa04657IL-17 signaling pathway7.96E-0810P07900, O00463, Q16539, P49841, P09341, P19875, P14780, P80188, P01375, P01584HSP90AA1, TRAF5, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, LCN2, TNF, IL1BMore
Ondansetronhsa04658Th1 and Th2 cell differentiation5.89E-2616Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, P13765, P23458, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, JAK1, RUNX3More
Ondansetronhsa04659Th17 cell differentiation3.91E-2222P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, P40189, Q9UL17, P23771, P84022, Q13485, P01584, P08238, P07766, P09693, P20963, P23458NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, IL6ST, TBX21, GATA3, SMAD3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Ondansetronhsa04660T cell receptor signaling pathway1.79E-2120P01375, P25963, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, P16333, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P04049, Q16539, P49841TNF, NFKBIA, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, NCK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, RAF1, MAPK14, GSK3BMore
Ondansetronhsa04662B cell receptor signaling pathway1.65E-1012P49841, P31751, P42338, P20023, P60033, P13164, Q8WV28, P07948, P11912, P21854, Q8N149, P04049GSK3B, AKT2, PIK3CB, CR2, CD81, IFITM1, BLNK, LYN, CD79A, CD72, LILRA2, RAF1More
Ondansetronhsa04664Fc epsilon RI signaling pathway1.94E-0911P01375, P31751, P04141, Q16539, P42338, P17252, Q9UQC2, P07948, P19174, P04049, P09917TNF, AKT2, CSF2, MAPK14, PIK3CB, PRKCA, GAB2, LYN, PLCG1, RAF1, ALOX5More
Ondansetronhsa04666Fc gamma R-mediated phagocytosis2.82E-079P42338, P19174, P04049, P23528, P49006, P06396, Q9UQC2, P14598, P17252PIK3CB, PLCG1, RAF1, CFL1, MARCKSL1, GSN, GAB2, NCF1, PRKCAMore
Ondansetronhsa04668TNF signaling pathway2.74E-0614P01375, O00463, Q13489, Q16539, P25963, Q99941, P18848, P19875, P01584, P20749, Q13077, P14780, P20333, O95429TNF, TRAF5, BIRC3, MAPK14, NFKBIA, CREBL1, ATF4, CXCL2, IL1B, BCL3, TRAF1, MMP9, TNFRSF1B, BAG4More
Ondansetronhsa04670Leukocyte transendothelial migration4.20E-027P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXKMore
Ondansetronhsa04710Circadian rhythm4.40E-021O15516CLOCKMore
Ondansetronhsa04713Circadian entrainment8.89E-058O15399, P0DP23, P17252, P62873, P63218, P50151, Q08828, P51828GRIN2D, CALM1, PRKCA, GNB1, GNG5, GNG10, ADCY1, ADCY7More
Ondansetronhsa04714Thermogenesis6.01E-048Q16539, P51828, P62753, P33121, P12074, O15239, Q16718, O14521MAPK14, ADCY7, RPS6, ACSL1, COX6A1, NDUFA1, NDUFA5, SDHDMore
Ondansetronhsa04720Long-term potentiation8.30E-069P17252, P16298, P0DP23, P51812, P18848, Q08828, Q02750, P04049, Q14643PRKCA, PPP3CB, CALM1, RPS6KA3, ATF4, ADCY1, MAP2K1, RAF1, ITPR1More
Ondansetronhsa04721Synaptic vesicle cycle3.15E-022Q13488, P31645TCIRG1, SLC6A4More
Ondansetronhsa04722Neurotrophin signaling pathway2.01E-046P31751, P04049, P49841, O43524, P48023, P0DP23AKT2, RAF1, GSK3B, FOXO3, FASLG, CALM1More
Ondansetronhsa04723Retrograde endocannabinoid signaling4.40E-025Q14643, P63218, P50151, P22694, Q16539ITPR1, GNG5, GNG10, PRKACB, MAPK14More
Ondansetronhsa04724Glutamatergic synapse6.66E-066O15399, P17252, P62873, P63218, P50151, P15104GRIN2D, PRKCA, GNB1, GNG5, GNG10, GLULMore
Ondansetronhsa04725Cholinergic synapse1.83E-0510Q08828, P51828, P17252, P62873, P63218, P50151, P18848, Q13557, P42338, P31751ADCY1, ADCY7, PRKCA, GNB1, GNG5, GNG10, ATF4, CAMK2D, PIK3CB, AKT2More
Ondansetronhsa04726Serotonergic synapse4.22E-047P17252, P62873, P63218, P50151, P33260, P09917, P04049PRKCA, GNB1, GNG5, GNG10, CYP2C18, ALOX5, RAF1More
Ondansetronhsa04727GABAergic synapse6.10E-065P62873, P63218, P50151, P15104, P17252GNB1, GNG5, GNG10, GLUL, PRKCAMore
Ondansetronhsa04728Dopaminergic synapse1.25E-0814P14416, P63218, P50151, P31751, P49841, Q99941, P18848, Q16539, Q13557, P49407, Q13362, Q14738, P0DP23, P48058DRD2, GNG5, GNG10, AKT2, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, PPP2R5C, PPP2R5D, CALM1, GRIA4More
Ondansetronhsa04730Long-term depression4.37E-034Q14344, P08069, P04049, P07948GNA13, IGF1R, RAF1, LYNMore
Ondansetronhsa04740Olfactory transduction9.46E-042Q9H255, P0DP23OR51E2, CALM1More
Ondansetronhsa04742Taste transduction7.70E-042P30939, P17612HTR1F, PRKACAMore
Ondansetronhsa04744Phototransduction6.26E-052P62873, P0DP23GNB1, CALM1More
Ondansetronhsa04750Inflammatory mediator regulation of TRP channels2.57E-0914P14778, P01584, Q08828, P51828, P22694, Q13557, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, CAMK2D, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2, CALM1More
Ondansetronhsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Ondansetronhsa04910Insulin signaling pathway2.40E-053P0DP23, P04049, P31751CALM1, RAF1, AKT2More
Ondansetronhsa04911Insulin secretion1.68E-065Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Ondansetronhsa04912GnRH signaling pathway2.72E-0512P17252, Q08828, P51828, P18848, Q13557, Q16539, Q9Y6R4, Q14643, P0DP24, P0DP23, P22694, P04049PRKCA, ADCY1, ADCY7, ATF4, CAMK2D, MAPK14, MAP3K4, ITPR1, CALM2, CALM1, PRKACB, RAF1More
Ondansetronhsa04913Ovarian steroidogenesis5.67E-044P42330, P22694, P06213, P08069AKR1C3, PRKACB, INSR, IGF1RMore
Ondansetronhsa04914Progesterone-mediated oocyte maturation8.26E-0811P08069, Q17RY0, P42338, Q13370, Q9UJX4, Q9Y6D9, P30304, P08238, P51812, Q02750, P04049IGF1R, CPEB4, PIK3CB, PDE3B, ANAPC5, MAD1L1, CDC25A, HSP90AB1, RPS6KA3, MAP2K1, RAF1More
Ondansetronhsa04915Estrogen signaling pathway1.66E-0711P04049, Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, P0DP23, Q15788RAF1, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, CALM1, NCOA1More
Ondansetronhsa04916Melanogenesis5.16E-056P0DP23, Q08828, P51828, P49841, Q01726, P04049CALM1, ADCY1, ADCY7, GSK3B, MC1R, RAF1More
Ondansetronhsa04917Prolactin signaling pathway6.79E-054P31751, P42338, P04049, P49841AKT2, PIK3CB, RAF1, GSK3BMore
Ondansetronhsa04918Thyroid hormone synthesis1.98E-045P51828, Q99941, P18848, P14625, P02768ADCY7, CREBL1, ATF4, HSP90B1, ALBMore
Ondansetronhsa04919Thyroid hormone signaling pathway1.82E-021P04049RAF1More
Ondansetronhsa04920Adipocytokine signaling pathway6.24E-047P25963, Q06124, P33121, Q9Y478, Q04759, P31751, P01375NFKBIA, PTPN11, ACSL1, PRKAB1, PRKCQ, AKT2, TNFMore
Ondansetronhsa04921Oxytocin signaling pathway4.61E-034P0DP23, P04049, Q96RR4, Q13469CALM1, RAF1, CAMKK2, NFATC2More
Ondansetronhsa04922Glucagon signaling pathway4.86E-044P14618, P06737, P31751, P0DP23PKM2, PYGL, AKT2, CALM1More
Ondansetronhsa04923Regulation of lipolysis in adipocytes9.57E-067Q08828, P51828, P07550, P06213, P42338, Q9Y4H2, P31751ADCY1, ADCY7, ADRB2, INSR, PIK3CB, IRS2, AKT2More
Ondansetronhsa04924Renin secretion5.35E-044P22694, P07550, Q13370, P0DP23PRKACB, ADRB2, PDE3B, CALM1More
Ondansetronhsa04925Aldosterone synthesis and secretion6.61E-0810Q14643, Q99941, P18848, Q08828, P51828, P0DP23, P17252, Q13557, P20020, P23634ITPR1, CREBL1, ATF4, ADCY1, ADCY7, CALM1, PRKCA, CAMK2D, ATP2B1, ATP2B4More
Ondansetronhsa04926Relaxin signaling pathway7.36E-0817P31751, P25963, P42338, P62873, P63218, P50151, Q99941, P18848, P22694, P49767, P14780, Q08828, P51828, P04049, P17252, P30679, P49407AKT2, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, CREBL1, ATF4, PRKACB, VEGFC, MMP9, ADCY1, ADCY7, RAF1, PRKCA, GNA15, ARRB1More
Ondansetronhsa04927Cortisol synthesis and secretion1.02E-055Q99941, P18848, Q08828, P51828, P22694CREBL1, ATF4, ADCY1, ADCY7, PRKACBMore
Ondansetronhsa04928Parathyroid hormone synthesis, secretion and action3.95E-034P51828, P04049, Q99941, P18848ADCY7, RAF1, CREBL1, ATF4More
Ondansetronhsa04929GnRH secretion4.39E-064P42338, P31751, P49407, P04049PIK3CB, AKT2, ARRB1, RAF1More
Ondansetronhsa04930Type II diabetes mellitus3.14E-021P06213INSRMore
Ondansetronhsa04931Insulin resistance1.48E-022Q06124, Q9Y478PTPN11, PRKAB1More
Ondansetronhsa04932Non-alcoholic fatty liver disease2.91E-0914P31751, P01375, P49841, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, Q16718, O95298, O14521AKT2, TNF, GSK3B, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFA5, NDUFC2, SDHDMore
Ondansetronhsa04933AGE-RAGE signaling pathway in diabetic complications2.76E-037P84022, Q13485, P42224, P42338, P49767, P17252, P19174SMAD3, SMAD4, STAT1, PIK3CB, VEGFC, PRKCA, PLCG1More
Ondansetronhsa04934Cushing syndrome2.24E-066Q99941, P18848, Q08828, P51828, O15169, Q13557CREBL1, ATF4, ADCY1, ADCY7, AXIN1, CAMK2DMore
Ondansetronhsa04935Growth hormone synthesis, secretion and action3.68E-046Q08828, P51828, P04049, Q99941, P18848, P31751ADCY1, ADCY7, RAF1, CREBL1, ATF4, AKT2More
Ondansetronhsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Ondansetronhsa04960Aldosterone-regulated sodium reabsorption1.18E-044O00141, P06213, P42338, P48048SGK, INSR, PIK3CB, KCNJ1More
Ondansetronhsa04962Vasopressin-regulated water reabsorption1.80E-022P62491, P46459RAB11A, NSFMore
Ondansetronhsa04964Proximal tubule bicarbonate reclamation4.48E-021P00918CA2More
Ondansetronhsa04966Collecting duct acid secretion2.19E-033P02730, P00918, Q9Y666SLC4A1, CA2, SLC12A7More
Ondansetronhsa04970Salivary secretion1.55E-079P07550, Q08828, P51828, P22694, Q14643, P20020, P17252, P0DP23, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, ATP2B1, PRKCA, CALM1, CAMPMore
Ondansetronhsa04971Gastric acid secretion2.02E-067Q08828, P51828, P15311, P48048, P78508, P0DP23, Q13557ADCY1, ADCY7, VIL2, KCNJ1, KCNJ10, CALM1, CAMK2DMore
Ondansetronhsa04972Pancreatic secretion4.29E-055Q14643, P20020, P17252, Q08828, P62491ITPR1, ATP2B1, PRKCA, ADCY1, RAB11AMore
Ondansetronhsa04973Carbohydrate digestion and absorption4.61E-033O43451, P42338, P31751MGAM, PIK3CB, AKT2More
Ondansetronhsa04974Protein digestion and absorption2.78E-021P02452COL1A1More
Ondansetronhsa04976Bile secretion1.67E-056O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Ondansetronhsa04979Cholesterol metabolism1.61E-022P38571, P61916LIPA, NPC2More
Ondansetronhsa05010Alzheimer disease2.89E-0718Q92542, O95298, P05496, P13073, P12074, Q00535, O75460, P0DP24, P0DP23, P01584, P18848, O15169, P31751, P05141, P45880, P17861, P28070, P62195NCSTN, NDUFC2, ATP5G1, COX4I1, COX6A1, CDK5, ERN1, CALM2, CALM1, IL1B, ATF4, AXIN1, AKT2, SLC25A5, VDAC2, XBP1, PSMB4, PSMC5More
Ondansetronhsa05012Parkinson disease1.07E-0313P13073, P05141, P60604, O75460, P18848, P17861, P62195, P19174, P0DP23, P0DP24, Q71U36, Q13509, P68371COX4I1, SLC25A5, UBE2G2, ERN1, ATF4, XBP1, PSMC5, PLCG1, CALM1, CALM2, TUBA1A, TUBB3, TUBB2CMore
Ondansetronhsa05014Amyotrophic lateral sclerosis2.32E-043P17861, P62195, Q53GS7XBP1, PSMC5, GLE1More
Ondansetronhsa05016Huntington disease1.54E-0613O95298, P13073, P12074, Q9GZM3, P24928, P30876, P62487, P52435, P05141, Q9NYC9, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2J2, POLR2A, POLR2B, POLR2G, POLR2J, SLC25A5, DNAH9, ERN1, PSMB4, PSMD12More
Ondansetronhsa05017Spinocerebellar ataxia2.83E-036O75460, P31751, P17861, P28070, P62195, P05141ERN1, AKT2, XBP1, PSMB4, PSMC5, SLC25A5More
Ondansetronhsa05020Prion disease1.37E-0311P01584, P46531, P11142, Q16718, O14521, P05496, P12074, P45880, P49841, Q99941, Q16539IL1B, NOTCH1, HSPA8, NDUFA5, SDHD, ATP5G1, COX6A1, VDAC2, GSK3B, CREBL1, MAPK14More
Ondansetronhsa05022Pathways of neurodegeneration - multiple diseases2.61E-0620P49841, Q16718, O95298, O14521, P13073, Q8TEV9, O75460, P18848, P17861, Q13561, P05141, P20333, Q16539, Q00535, P01584, Q08752, P0DP24, P0DP23, P28070, P62195GSK3B, NDUFA5, NDUFC2, SDHD, COX4I1, SMCR8, ERN1, ATF4, XBP1, DCTN2, SLC25A5, TNFRSF1B, MAPK14, CDK5, IL1B, PPID, CALM2, CALM1, PSMB4, PSMC5More
Ondansetronhsa05030Cocaine addiction6.96E-033Q00535, Q99941, P18848CDK5, CREBL1, ATF4More
Ondansetronhsa05031Amphetamine addiction1.45E-046P0DP23, Q13557, P22694, Q99941, P18848, Q13547CALM1, CAMK2D, PRKACB, CREBL1, ATF4, HDAC1More
Ondansetronhsa05032Morphine addiction7.16E-046P62873, P63218, P50151, Q13370, P17252, P43250GNB1, GNG5, GNG10, PDE3B, PRKCA, GRK6More
Ondansetronhsa05034Alcoholism1.81E-068Q13547, P04049, Q93077, P58876, P62807, Q16778, O60814, P68431HDAC1, RAF1, HIST1H2AC, H2BC5, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Ondansetronhsa05100Bacterial invasion of epithelial cells1.82E-034Q14141, Q05397, Q92529, Q96JJ3SEPT6, PTK2, SHC3, ELMO2More
Ondansetronhsa05110Vibrio cholerae infection5.33E-045Q13488, Q99437, P17252, P19174, P17612TCIRG1, ATP6V0B, PRKCA, PLCG1, PRKACAMore
Ondansetronhsa05120Epithelial cell signaling in Helicobacter pylori infection2.77E-1111Q16539, P25963, Q13488, Q99437, P09341, P19875, P19174, P25024, P25025, P41240, P07948MAPK14, NFKBIA, TCIRG1, ATP6V0B, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2, CSK, LYNMore
Ondansetronhsa05130Pathogenic Escherichia coli infection3.19E-026Q71U36, P16333, Q13509, P68371, Q14344, P25963TUBA1A, NCK1, TUBB3, TUBB2C, GNA13, NFKBIAMore
Ondansetronhsa05131Shigellosis3.62E-0318P01375, P25963, O00463, P14778, Q16539, Q04759, Q9UDY8, P61088, Q9NQL2, Q9H1Y0, P12814, Q14643, Q12778, P49841, Q13315, P10415, P21796, Q96A32TNF, NFKBIA, TRAF5, IL1R1, MAPK14, PRKCQ, MALT1, UBE2N, RRAGD, ATG5, ACTN1, ITPR1, FOXO1, GSK3B, ATM, BCL2, VDAC1, MYLPFMore
Ondansetronhsa05132Salmonella infection1.77E-0620P51617, P25963, P01375, P08238, P04049, Q9UJU2, P63261, Q13546, Q13489, P10415, O75369, Q96A32, O60603, Q9BQS8, P51808, Q13561, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, TNF, HSP90AB1, RAF1, LEF1, ACTG1, RIPK1, BIRC3, BCL2, FLNB, MYLPF, TLR2, FYCO1, DYNLT3, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41More
Ondansetronhsa05133Pertussis3.51E-021P0C0L4C4AMore
Ondansetronhsa05134Legionellosis1.05E-048P01584, P25963, Q9NR31, P11215, P0DMV8, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, HSPA1A, HSPA8, CXCL1, CXCL2More
Ondansetronhsa05135Yersinia infection6.38E-039Q05397, P51812, P13612, P06239, Q16539, Q02750, P01375, P49841, Q96JJ3PTK2, RPS6KA3, ITGA4, LCK, MAPK14, MAP2K1, TNF, GSK3B, ELMO2More
Ondansetronhsa05140Leishmaniasis1.20E-1016P13612, O75015, P14598, P11215, P23458, P42224, P13765, O60603, P25963, P01375, P01584, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, ITGAM, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Ondansetronhsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Ondansetronhsa05144Malaria2.76E-096P60033, O60603, P01375, P35443, P01584, P26718CD81, TLR2, TNF, THBS4, IL1B, KLRK1More
Ondansetronhsa05145Toxoplasmosis2.98E-0311P51617, P25963, P01375, P10415, Q13489, P42224, P13765, P09917, Q13751, P11142, O60603IRAK1, NFKBIA, TNF, BCL2, BIRC3, STAT1, HLA-DOB, ALOX5, LAMB3, HSPA8, TLR2More
Ondansetronhsa05146Amoebiasis3.61E-1714P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P30679, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1, CTSGMore
Ondansetronhsa05150Staphylococcus aureus infection9.74E-0712P09871, P0C0L4, P21730, P21462, O75015, P13646, Q14532, P16109, P59665, P59666, P12838, P49913C1S, C4A, C5AR1, FPR1, FCGR3B, KRT13, KRT32, SELP, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Ondansetronhsa05152Tuberculosis4.72E-0414P04049, Q13488, Q15075, P0DP23, P48382, O60603, P01375, P31751, P10415, P13765, Q13651, P49913, Q9UDY8, P51617RAF1, TCIRG1, EEA1, CALM1, RFX5, TLR2, TNF, AKT2, BCL2, HLA-DOB, IL10RA, CAMP, MALT1, IRAK1More
Ondansetronhsa05160Hepatitis C1.31E-047Q13546, P01568, P60033, P04049, P49841, P01375, P48023RIPK1, IFNA21, CD81, RAF1, GSK3B, TNF, FASLGMore
Ondansetronhsa05161Hepatitis B5.07E-0412P17252, P04049, P14780, Q99941, P18848, P25963, P01375, P10415, P27348, P51617, O60603, Q14765PRKCA, RAF1, MMP9, CREBL1, ATF4, NFKBIA, TNF, BCL2, YWHAQ, IRAK1, TLR2, STAT4More
Ondansetronhsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Ondansetronhsa05163Human cytomegalovirus infection2.43E-1428P31751, P42338, P04049, P01375, P25963, P62873, P63218, P50151, Q14643, P0DP23, Q14344, Q8NHW4, Q08828, P51828, P22694, P23458, P49841, P14778, P01584, P17252, Q13651, P25025, Q16539, P18848, P04637, O00463, P30101, P01568AKT2, PIK3CB, RAF1, TNF, NFKBIA, GNB1, GNG5, GNG10, ITPR1, CALM1, GNA13, CCL4L2, ADCY1, ADCY7, PRKACB, JAK1, GSK3B, IL1R1, IL1B, PRKCA, IL10RA, CXCR2, MAPK14, ATF4, TP53, TRAF5, PDIA3, IFNA21More
Ondansetronhsa05164Influenza A1.49E-026P31751, P01584, P23458, P05141, P04049, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, RAF1, NXF1More
Ondansetronhsa05165Human papillomavirus infection1.20E-034P02452, P24821, P01568, P04628COL1A1, TNC, IFNA21, WNT1More
Ondansetronhsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Ondansetronhsa05167Kaposi sarcoma-associated herpesvirus infection3.77E-1020P01568, P31751, P42224, P25963, P42338, P40189, P23458, P62873, P62879, P63218, P50151, P19174, Q13469, P16298, P04049, Q02750, P07948, P04141, P0DP23, P0CG47IFNA21, AKT2, STAT1, NFKBIA, PIK3CB, IL6ST, JAK1, GNB1, GNB2, GNG5, GNG10, PLCG1, NFATC2, PPP3CB, RAF1, MAP2K1, LYN, CSF2, CALM1, UBBMore
Ondansetronhsa05168Herpes simplex virus 1 infection1.18E-0719P25963, P01568, Q05823, P42224, Q07955, Q01130, Q13243, Q13489, P30101, P42338, Q9Y2A4, Q13398, P51522, Q9HCX3, P17038, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, RNASEL, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PDIA3, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF304, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212More
Ondansetronhsa05169Epstein-Barr virus infection1.15E-0621P13765, P01106, Q13547, Q92769, P04637, Q13546, O00463, P10415, Q16539, P42338, P07948, Q13761, P24522, O75293, P01375, O60603, P29728, P51617, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, HDAC2, TP53, RIPK1, TRAF5, BCL2, MAPK14, PIK3CB, LYN, RUNX3, GADD45A, GADD45B, TNF, TLR2, OAS2, IRAK1, CD3E, CD3G, CD247More
Ondansetronhsa05170Human immunodeficiency virus 1 infection1.89E-1131P31751, P42338, P04049, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, P01375, Q05397, P17252, Q13546, O00463, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, O95067, P19174, P23528, P09693, P10415, Q13619, Q93034, Q9Y6Q5, P20333AKT2, PIK3CB, RAF1, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, TNF, PTK2, PRKCA, RIPK1, TRAF5, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, CCNB2, PLCG1, CFL1, CD3G, BCL2, CUL4A, CUL5, AP1M2, TNFRSF1BMore
Ondansetronhsa05171Coronavirus disease - COVID-192.77E-0520P01584, P25963, P42224, P01568, P23396, P62753, P62249, P62906, P36578, P27635, Q07020, P62888, P46776, P61927, P61513, P62829, P40189, P42338, P19174, P17252IL1B, NFKBIA, STAT1, IFNA21, RPS3, RPS6, RPS16, RPL10A, RPL4, RPL10, RPL18, RPL30, RPL27A, RPL37, RPL37A, RPL23, IL6ST, PIK3CB, PLCG1, PRKCAMore
Ondansetronhsa05200Pathways in cancer1.20E-0931Q13751, P42338, P08238, P42224, P25963, P19174, P17252, P43246, P84022, Q13485, P20585, Q13547, P10826, P14923, P30281, Q13489, P49767, P14921, P31751, P43657, P62873, P63218, P50151, Q14344, Q7LDG7, P78417, O75293, P0DP23, P01568, P14784, P40189LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, HDAC1, RARB, JUP, CCND3, BIRC3, VEGFC, ETS1, AKT2, P2RY5, GNB1, GNG5, GNG10, GNA13, RASGRP2, GSTO1, GADD45B, CALM1, IFNA21, IL2RB, IL6STMore
Ondansetronhsa05202Transcriptional misregulation in cancer8.16E-1126Q12778, Q15532, Q13315, P41732, P17844, P14780, P27930, P14923, Q15744, Q16548, P11215, Q13489, Q13077, O15550, P08069, P04637, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, SS18, ATM, TSPAN7, DDX5, MMP9, IL1R2, JUP, CEBPE, BCL2A1, ITGAM, BIRC3, TRAF1, UTX, IGF1R, TP53, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Ondansetronhsa05203Viral carcinogenesis8.75E-0711Q99941, P18848, P27348, Q13547, Q15283, P61978, P58876, P62807, P33778, Q16778, O60814CREBL1, ATF4, YWHAQ, HDAC1, RASA2, HNRPK, H2BC5, HIST1H2BC, H2BC3, HIST2H2BE, H2BC12More
Ondansetronhsa05204Chemical carcinogenesis2.96E-042P78417, P11712GSTO1, CYP2C9More
Ondansetronhsa05205Proteoglycans in cancer4.46E-0413Q14643, P63261, P04049, P04637, P14780, P17252, O60603, P01375, P08069, P23588, Q13635, P22694, P08962ITPR1, ACTG1, RAF1, TP53, MMP9, PRKCA, TLR2, TNF, IGF1R, EIF4B, PTCH1, PRKACB, CD63More
Ondansetronhsa05206MicroRNAs in cancer6.19E-047P15311, P21860, P61978, P46531, P63279, P22105, P04049VIL2, ERBB3, HNRPK, NOTCH1, UBE2I, TNXB, RAF1More
Ondansetronhsa05210Colorectal cancer2.55E-033Q9UKG1, P04049, P37173APPL1, RAF1, TGFBR2More
Ondansetronhsa05211Renal cell carcinoma1.29E-032P31751, P04049AKT2, RAF1More
Ondansetronhsa05212Pancreatic cancer3.15E-0810P42338, P31751, P04049, Q15311, P23458, P42224, P37173, P84022, Q13485, O75293PIK3CB, AKT2, RAF1, RALBP1, JAK1, STAT1, TGFBR2, SMAD3, SMAD4, GADD45BMore
Ondansetronhsa05213Endometrial cancer3.02E-056O15169, P49841, P31751, P42338, Q02750, P04049AXIN1, GSK3B, AKT2, PIK3CB, MAP2K1, RAF1More
Ondansetronhsa05214Glioma3.98E-1010P08069, P0DP23, P17252, P04049, P42338, P31751, P04637, P19174, P24522, O75293IGF1R, CALM1, PRKCA, RAF1, PIK3CB, AKT2, TP53, PLCG1, GADD45A, GADD45BMore
Ondansetronhsa05215Prostate cancer6.90E-067P08069, P18848, P49841, P14625, P42338, P04049, P27930IGF1R, ATF4, GSK3B, HSP90B1, PIK3CB, RAF1, IL1R2More
Ondansetronhsa05216Thyroid cancer1.50E-045P01106, Q9UJU2, P04637, P24522, O75293MYC, LEF1, TP53, GADD45A, GADD45BMore
Ondansetronhsa05217Basal cell carcinoma1.85E-045Q13635, P49841, Q9UJU2, P04637, P24522PTCH1, GSK3B, LEF1, TP53, GADD45AMore
Ondansetronhsa05218Melanoma5.24E-063P08069, P31751, P04049IGF1R, AKT2, RAF1More
Ondansetronhsa05219Bladder cancer5.65E-033P14780, P04637, P04049MMP9, TP53, RAF1More
Ondansetronhsa05220Chronic myeloid leukemia4.90E-047Q13547, Q13485, P84022, P31751, P42338, P04049, O75293HDAC1, SMAD4, SMAD3, AKT2, PIK3CB, RAF1, GADD45BMore
Ondansetronhsa05221Acute myeloid leukemia8.16E-042P31751, P04049AKT2, RAF1More
Ondansetronhsa05222Small cell lung cancer1.36E-0411P10826, P31751, P42338, Q13751, Q13489, P10415, P25963, Q13077, O00463, P24522, O75293RARB, AKT2, PIK3CB, LAMB3, BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45A, GADD45BMore
Ondansetronhsa05223Non-small cell lung cancer1.14E-078P17252, P31751, P42338, P19174, P10826, P04049, Q9HC35, O75293PRKCA, AKT2, PIK3CB, PLCG1, RARB, RAF1, EML4, GADD45BMore
Ondansetronhsa05224Breast cancer3.67E-047P04049, P08069, P42338, P49841, Q92837, P04637, P24522RAF1, IGF1R, PIK3CB, GSK3B, FRAT1, TP53, GADD45AMore
Ondansetronhsa05225Hepatocellular carcinoma2.16E-058P04049, P08069, P42338, P49841, Q92922, P51531, P78417, Q9NPI1RAF1, IGF1R, PIK3CB, GSK3B, SMARCC1, SMARCA2, GSTO1, BRD7More
Ondansetronhsa05226Gastric cancer5.51E-056P04049, Q02750, P31751, O15169, P04628, P10826RAF1, MAP2K1, AKT2, AXIN1, WNT1, RARBMore
Ondansetronhsa05230Central carbon metabolism in cancer1.12E-032P04049, P31751RAF1, AKT2More
Ondansetronhsa05231Choline metabolism in cancer8.65E-0810P04049, P31751, P42338, Q9Y259, P19174, P23743, P49619, Q16760, O14986, P17252RAF1, AKT2, PIK3CB, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PRKCAMore
Ondansetronhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer9.15E-1616P42338, O95267, P19174, P07766, P20963, P09693, P06239, P04049, P23458, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, RAF1, JAK1, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Ondansetronhsa05310Asthma1.34E-043P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Ondansetronhsa05321Inflammatory bowel disease2.21E-118O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1B, IL21RMore
Ondansetronhsa05322Systemic lupus erythematosus1.37E-0816P08246, P08311, P09871, P01375, P10747, P13765, Q6FI13, Q93077, P58876, P62807, P33778, Q16778, O60814, P68431, P12814, P05455ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST1H2BC, H2BC3, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1, SSBMore
Ondansetronhsa05323Rheumatoid arthritis1.91E-034P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Ondansetronhsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Ondansetronhsa05332Graft-versus-host disease4.78E-106P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Ondansetronhsa05340Primary immunodeficiency1.73E-066P01730, P01732, P11912, Q8WV28, P07766, P06239CD4, CD8A, CD79A, BLNK, CD3E, LCKMore
Ondansetronhsa05412Arrhythmogenic right ventricular cardiomyopathy4.48E-021P54284CACNB3More
Ondansetronhsa05414Dilated cardiomyopathy4.55E-022P54284, P26678CACNB3, PLNMore
Ondansetronhsa05415Diabetic cardiomyopathy7.18E-0510P17252, P30405, P14598, Q15080, Q16718, O14521, Q16539, P49841, P37173, P04406PRKCA, PPIF, NCF1, NCF4, NDUFA5, SDHD, MAPK14, GSK3B, TGFBR2, GAPDHMore
Ondansetronhsa05418Fluid shear stress and atherosclerosis1.15E-0916Q16539, P31751, P42338, Q14145, P14598, P10599, P14780, P01375, P63261, P04637, P10415, P14778, P27930, P0DP23, P08238, Q92974MAPK14, AKT2, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, ACTG1, TP53, BCL2, IL1R1, IL1R2, CALM1, HSP90AB1, ARHGEF2More

Community members of Ondansetron (SDC: 11.58)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
Q9Y2I1NISCHNischarinPredicted10.60820.225100.7543
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P49760CLK2Dual specificity protein kinase CLK2Predicted00.03030.295100.6053
P11511CYP19A1AromatasePredicted00.815610.15882.5666
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
Q16875PFKFB36NonephosphofructoNone2Nonekinase/fructoseNone2,6Nonebisphosphatase 3Predicted10.04620.08860.23420.4345
P08238HSP90AB1Heat shock protein HSP 90NonebetaPredicted00.06110.52080.7411.8131
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
O95497VNN1PantetheinasePredicted00.13040.01110.01430.1018
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
O14684PTGESProstaglandin E synthasePredicted10.45310.63580.15651.6547
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
Q13093PLA2G7PlateletNoneactivating factor acetylhydrolasePredicted00.05050.20960.15580.6001
Q2M2I8AAK1AP2Noneassociated protein kinase 1Predicted10.37690.328800.846
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P11388TOP2ADNA topoisomerase 2NonealphaPredicted00.19920.46590.19271.2242
P49354FNTAProtein farnesyltransferase/geranylgeranyltransferase typeNone1 subunit alphaPredicted00.53030.758801.7827
P61073CXCR4CNoneXNoneC chemokine receptor type 4Predicted10.28230.40180.6481.5927
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
Q02750MAP2K1Dual specificity mitogenNoneactivated protein kinase kinase 1Predicted00.3120.512912.1819
P07947YES1TyrosineNoneprotein kinase YesPredicted00.12120.43450.1651.0947
Q15746MYLKMyosin light chain kinase, smooth musclePredicted00.04010.31160.42981.0731
P09769FGRTyrosineNoneprotein kinase FgrPredicted00.06220.32440.2250.9049
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
P01375TNFTumor necrosis factorPredicted10.18650.55112.1953
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
O95271TNKSPoly [ADPNoneribose] polymerase tankyraseNone1Predicted00.10170.222400.4957
Q06609RAD51DNA repair protein RAD51 homolog 1Predicted00.10220.09540.27250.5144
P17861XBP1XNoneboxNonebinding protein 1Predicted00.29140.06510.46080.7367
P51531SMARCA2Probable global transcription activator SNF2L2Predicted00.22310.0450.13750.3391
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
P30304CDC25AMNonephase inducer phosphatase 1Predicted00.17950.23470.42740.9865
P17612PRKACAcAMPNonedependent protein kinase catalytic subunit alphaPredicted00.69370.525712.3982
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
Q16769QPCTGlutaminylNonepeptide cyclotransferasePredicted00.02450.241600.4954
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
Q9Y478PRKAB15'NoneAMPNoneactivated protein kinase subunit betaNone1Predicted10.14780.10880.55640.8479
P31751AKT2RACNonebeta serine/threonineNoneprotein kinasePredicted00.46620.485612.2044
P22001KCNA3Potassium voltageNonegated channel subfamily A member 3Predicted10.13960.505501.0809
O00141SGKSerine/threonineNoneprotein kinase Sgk1Predicted00.24130.30370.30591.034
Q9GZT9EGLN1Egl nine homolog 1Predicted00.58040.60610.25561.7581
P37173TGFBR2TGFNonebeta receptor typeNone2Predicted00.28670.3790.87421.7755
P07900HSP90AA1Heat shock protein HSP 90NonealphaPredicted10.47270.60640.7412.1901
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
P29375JARID1ALysineNonespecific demethylase 5APredicted00.36050.705201.5906
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
P51813BMXCytoplasmic tyrosineNoneprotein kinase BMXPredicted00.05970.326300.6825
P42681TXKTyrosineNoneprotein kinase TXKPredicted00.28040.30260.19130.9367
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
P14625HSP90B1EndoplasminPredicted00.23360.14970.53840.9546
P09960LTA4HLeukotriene ANone4 hydrolasePredicted00.2770.95190.15652.1988
P49281SLC11A2Natural resistanceNoneassociated macrophage protein 2Predicted10.33250.05050.26620.5334
Q9NPI1BRD7BromodomainNonecontaining protein 7Predicted00.03190.02750.12130.1923
Q9UBU7DBF4Protein DBF4 homolog APredicted00.00750.19610.2590.655
P16083NQO2Ribosyldihydronicotinamide dehydrogenase [quinone]Predicted00.29580.313400.7747
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
P21462FPR1fMetNoneLeuNonePhe receptorPredicted00.12050.34920.43781.1964
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P25024CXCR1CNoneXNoneC chemokine receptor type 1Predicted10.16560.42320.40091.33
P50052AGTR2TypeNone2 angiotensin II receptorPredicted10.06040.43650.15411.0572
P51684CCR6CNoneC chemokine receptor type 6Predicted00.0850.17410.33040.7212
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)