| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
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| Oleic-Acid | hsa00512 | Mucin type O-glycan biosynthesis | 3.78E-02 | 2 | O95395, Q8N4A0 | GCNT3, GALNT4 | More | | | Oleic-Acid | hsa00520 | Amino sugar and nucleotide sugar metabolism | 7.87E-03 | 3 | Q16222, Q9Y223, P06865 | UAP1, GNE, HEXA | More | | | Oleic-Acid | hsa00533 | Glycosaminoglycan biosynthesis - keratan sulfate | 3.43E-02 | 1 | Q9NY97 | B3GNT2 | More | | | Oleic-Acid | hsa00603 | Glycosphingolipid biosynthesis - globo and isoglobo series | 4.30E-03 | 2 | P06865, O75752 | HEXA, B3GALNT1 | More | | | Oleic-Acid | hsa00630 | Glyoxylate and dicarboxylate metabolism | 4.46E-03 | 2 | P40925, P15104 | MDH1, GLUL | More | | | Oleic-Acid | hsa00920 | Sulfur metabolism | 3.18E-02 | 1 | Q16762 | TST | More | | | Oleic-Acid | hsa00970 | Aminoacyl-tRNA biosynthesis | 3.78E-02 | 2 | O95363, Q15046 | FARS2, KARS | More | | | Oleic-Acid | hsa01200 | Carbon metabolism | 4.06E-02 | 5 | P37837, O14521, P50213, P60891, Q02252 | TALDO1, SDHD, IDH3A, PRPS1, ALDH6A1 | More | | | Oleic-Acid | hsa03013 | RNA transport | 4.73E-04 | 15 | P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q7Z3B4, P35658, P63279, Q14152, P55884, O15371, O75822, P20042, Q9Y6A5 | NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, NUP54, NUP214, UBE2I, EIF3A, EIF3B, EIF3D, EIF3J, EIF2S2, TACC3 | More | | | Oleic-Acid | hsa03040 | Spliceosome | 2.42E-07 | 16 | O43143, O60508, P08579, Q15427, P26368, P38159, P61978, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643 | DHX15, CDC40, SNRPB2, SF3B4, U2AF2, RBMX, HNRPK, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1 | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O43143 | DHX15 | ATP-dependent RNA helicase DHX15 | -0.76 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | O60508 | CDC40 | Pre-mRNA-processing factor 17 | 0.76 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O60508 | CDC40 | Pre-mRNA-processing factor 17 | -0.812 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | P08579 | SNRPB2 | U2 small nuclear ribonucleoprotein B'' | 0.787 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P08579 | SNRPB2 | U2 small nuclear ribonucleoprotein B'' | -0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Q15427 | SF3B4 | Splicing factor 3B subunit 4 | 0.71 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P26368 | U2AF2 | Splicing factor U2AF 65 kDa subunit | -0.751 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P38159 | RBMX | RNA-binding motif protein, X chromosome | 0.733 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P61978 | HNRPK | Heterogeneous nuclear ribonucleoprotein K | 0.784 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13595 | TRA2A | Transformer-2 protein homolog alpha | -0.74 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | Q07955 | SFRS1 | Serine/arginine-rich splicing factor 1 | 0.712 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q07955 | SFRS1 | Serine/arginine-rich splicing factor 1 | -0.749 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | Q01130 | SFRS2 | Serine/arginine-rich splicing factor 2 | 0.822 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q01130 | SFRS2 | Serine/arginine-rich splicing factor 2 | -0.798 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P84103 | SFRS3 | Serine/arginine-rich splicing factor 3 | -0.773 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q13243 | SFRS5 | Serine/arginine-rich splicing factor 5 | -0.822 | | P49354 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | P11142 | HSPA8 | Heat shock cognate 71 kDa protein | 0.766 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P11142 | HSPA8 | Heat shock cognate 71 kDa protein | -0.802 | | P35610 | SOAT1 | Sterol O-acyltransferase 1 | Q9Y2W2 | WBP11 | WW domain-binding protein 11 | 0.711 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | Q9Y2W2 | WBP11 | WW domain-binding protein 11 | -0.743 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O43447 | PPIH | Peptidyl-prolyl cis-trans isomerase H | -0.766 | | P09917 | ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | O75643 | ASCC3L1 | U5 small nuclear ribonucleoprotein 200 kDa helicase | -0.745 |
| | Oleic-Acid | hsa03060 | Protein export | 1.43E-02 | 2 | P37108, Q15005 | SRP14, SPCS2 | More | | | Oleic-Acid | hsa03320 | PPAR signaling pathway | 3.78E-02 | 2 | Q6PCB7, Q9UNU6 | SLC27A1, CYP8B1 | More | | | Oleic-Acid | hsa04012 | ErbB signaling pathway | 3.74E-02 | 3 | P21860, Q13557, O14944 | ERBB3, CAMK2D, EREG | More | | | Oleic-Acid | hsa04014 | Ras signaling pathway | 1.98E-03 | 8 | P42338, P20827, P49767, Q13009, Q7LDG7, P63218, P50151, P19174 | PIK3CB, EFNA1, VEGFC, TIAM1, RASGRP2, GNG5, GNG10, PLCG1 | More | | | Oleic-Acid | hsa04015 | Rap1 signaling pathway | 2.69E-03 | 11 | P20827, P49767, Q96FS4, P11215, P25116, Q8TEU7, Q13009, Q7LDG7, P42338, P08514, P19174 | EFNA1, VEGFC, SIPA1, ITGAM, F2R, RAPGEF6, TIAM1, RASGRP2, PIK3CB, ITGA2B, PLCG1 | More | | | Oleic-Acid | hsa04020 | Calcium signaling pathway | 6.50E-04 | 6 | Q96DU7, P45880, Q13557, P21860, P51828, P23634 | ITPKC, VDAC2, CAMK2D, ERBB3, ADCY7, ATP2B4 | More | | | Oleic-Acid | hsa04022 | cGMP-PKG signaling pathway | 4.72E-02 | 4 | Q99941, P23634, P51828, P45880 | CREBL1, ATP2B4, ADCY7, VDAC2 | More | | | Oleic-Acid | hsa04062 | Chemokine signaling pathway | 9.23E-03 | 10 | P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q7LDG7, Q13009, Q8WYR1 | FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, RASGRP2, TIAM1, PIK3R5 | More | | | Oleic-Acid | hsa04114 | Oocyte meiosis | 1.62E-04 | 5 | Q9Y6D9, P51812, Q02750, P16298, Q17RY0 | MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4 | More | | | Oleic-Acid | hsa04122 | Sulfur relay system | 3.18E-02 | 1 | Q16762 | TST | More | | | Oleic-Acid | hsa04141 | Protein processing in endoplasmic reticulum | 3.64E-02 | 5 | Q99941, O75460, P11142, Q9H3Z4, P07900 | CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1 | More | | | Oleic-Acid | hsa04150 | mTOR signaling pathway | 3.60E-02 | 3 | Q02750, Q9NQL2, P51812 | MAP2K1, RRAGD, RPS6KA3 | More | | | Oleic-Acid | hsa04151 | PI3K-Akt signaling pathway | 1.89E-03 | 12 | P42338, P43657, P20827, P49767, P08238, Q8WYR1, P63218, P50151, O15335, Q13751, P14784, P30281 | PIK3CB, P2RY5, EFNA1, VEGFC, HSP90AB1, PIK3R5, GNG5, GNG10, CHAD, LAMB3, IL2RB, CCND3 | More | | | Oleic-Acid | hsa04211 | Longevity regulating pathway | 3.63E-02 | 3 | Q08828, Q99941, Q96RR4 | ADCY1, CREBL1, CAMKK2 | More | | | Oleic-Acid | hsa04215 | Apoptosis - multiple species | 1.56E-02 | 2 | Q13489, P10415 | BIRC3, BCL2 | More | | | Oleic-Acid | hsa04261 | Adrenergic signaling in cardiomyocytes | 3.98E-02 | 4 | P51828, Q99941, Q13557, P23634 | ADCY7, CREBL1, CAMK2D, ATP2B4 | More | | | Oleic-Acid | hsa04270 | Vascular smooth muscle contraction | 8.93E-03 | 4 | P0DP24, Q08828, P35579, P35318 | CALM2, ADCY1, MYH9, ADM | More | | | Oleic-Acid | hsa04330 | Notch signaling pathway | 4.34E-02 | 2 | Q92542, P46531 | NCSTN, NOTCH1 | More | | | Oleic-Acid | hsa04360 | Axon guidance | 4.04E-02 | 6 | P16333, P20827, O95631, P42338, P07332, P19174 | NCK1, EFNA1, NTN1, PIK3CB, FES, PLCG1 | More | | | Oleic-Acid | hsa04370 | VEGF signaling pathway | 1.43E-05 | 3 | P16298, Q05397, Q02750 | PPP3CB, PTK2, MAP2K1 | More | | | Oleic-Acid | hsa04371 | Apelin signaling pathway | 1.00E-02 | 7 | P63218, P50151, Q8WYR1, Q14814, Q14344, Q13485, P84022 | GNG5, GNG10, PIK3R5, MEF2D, GNA13, SMAD4, SMAD3 | More | | | Oleic-Acid | hsa04390 | Hippo signaling pathway | 2.08E-02 | 3 | P84022, Q13485, Q13489 | SMAD3, SMAD4, BIRC3 | More | | | Oleic-Acid | hsa04512 | ECM-receptor interaction | 3.73E-02 | 2 | P07359, P08514 | GP1BA, ITGA2B | More | | | Oleic-Acid | hsa04514 | Cell adhesion molecules | 8.19E-03 | 3 | P16109, P56750, O00501 | SELP, CLDN17, CLDN5 | More | | | Oleic-Acid | hsa04530 | Tight junction | 1.38E-04 | 5 | Q8TEU7, P16989, P56750, O00501, Q14247 | RAPGEF6, CSDA, CLDN17, CLDN5, CTTN | More | | | Oleic-Acid | hsa04610 | Complement and coagulation cascades | 4.47E-02 | 2 | P25116, P09871 | F2R, C1S | More | | | Oleic-Acid | hsa04611 | Platelet activation | 5.18E-05 | 5 | P25116, P08514, Q15746, Q8WYR1, P07359 | F2R, ITGA2B, MYLK, PIK3R5, GP1BA | More | | | Oleic-Acid | hsa04613 | Neutrophil extracellular trap formation | 1.52E-03 | 17 | P17252, P16109, O60603, P08246, Q9UM07, Q92769, Q6FI13, O60814, P14598, Q15080, O75015, P21730, P08514, P21462, P07359, O43315, Q16539 | PRKCA, SELP, TLR2, ELA2, PADI4, HDAC2, H2AC18; H2AC19, H2BC12, NCF1, NCF4, FCGR3B, C5AR1, ITGA2B, FPR1, GP1BA, AQP9, MAPK14 | More | | | Oleic-Acid | hsa04650 | Natural killer cell mediated cytotoxicity | 2.21E-03 | 3 | P16298, P50591, Q02750 | PPP3CB, TNFSF10, MAP2K1 | More | | | Oleic-Acid | hsa04659 | Th17 cell differentiation | 2.08E-03 | 8 | P25963, P19174, P14784, P14778, P84022, Q13485, P08238, P07766 | NFKBIA, PLCG1, IL2RB, IL1R1, SMAD3, SMAD4, HSP90AB1, CD3E | More | | | Oleic-Acid | hsa04662 | B cell receptor signaling pathway | 9.03E-05 | 5 | P42338, P60033, P07948, P21854, Q8N149 | PIK3CB, CD81, LYN, CD72, LILRA2 | More | | | Oleic-Acid | hsa04664 | Fc epsilon RI signaling pathway | 1.29E-03 | 4 | P42338, P07948, P19174, P09917 | PIK3CB, LYN, PLCG1, ALOX5 | More | | | Oleic-Acid | hsa04668 | TNF signaling pathway | 4.74E-02 | 3 | Q99941, P01584, O95429 | CREBL1, IL1B, BAG4 | More | | | Oleic-Acid | hsa04710 | Circadian rhythm | 1.67E-02 | 2 | Q16526, Q9Y478 | CRY1, PRKAB1 | More | | | Oleic-Acid | hsa04720 | Long-term potentiation | 7.72E-04 | 3 | P16298, P51812, Q02750 | PPP3CB, RPS6KA3, MAP2K1 | More | | | Oleic-Acid | hsa04724 | Glutamatergic synapse | 3.24E-02 | 3 | P43003, P50151, P15104 | SLC1A3, GNG10, GLUL | More | | | Oleic-Acid | hsa04750 | Inflammatory mediator regulation of TRP channels | 3.74E-02 | 3 | P01584, P51828, Q13557 | IL1B, ADCY7, CAMK2D | More | | | Oleic-Acid | hsa04810 | Regulation of actin cytoskeleton | 2.58E-02 | 3 | Q15746, P08514, P25116 | MYLK, ITGA2B, F2R | More | | | Oleic-Acid | hsa04911 | Insulin secretion | 1.48E-02 | 3 | P51828, Q99941, Q13557 | ADCY7, CREBL1, CAMK2D | More | | | Oleic-Acid | hsa04912 | GnRH signaling pathway | 3.39E-02 | 4 | P17252, Q16539, Q9Y6R4, Q14643 | PRKCA, MAPK14, MAP3K4, ITPR1 | More | | | Oleic-Acid | hsa04914 | Progesterone-mediated oocyte maturation | 5.67E-04 | 4 | Q17RY0, Q9Y6D9, P51812, Q02750 | CPEB4, MAD1L1, RPS6KA3, MAP2K1 | More | | | Oleic-Acid | hsa04915 | Estrogen signaling pathway | 4.72E-02 | 4 | Q99941, P51828, P07900, P11142 | CREBL1, ADCY7, HSP90AA1, HSPA8 | More | | | Oleic-Acid | hsa04920 | Adipocytokine signaling pathway | 4.31E-02 | 2 | Q9Y478, Q96RR4 | PRKAB1, CAMKK2 | More | | | Oleic-Acid | hsa04925 | Aldosterone synthesis and secretion | 3.02E-04 | 6 | Q99941, Q08828, P51828, P0DP24, Q13557, P23634 | CREBL1, ADCY1, ADCY7, CALM2, CAMK2D, ATP2B4 | More | | | Oleic-Acid | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 2.11E-03 | 6 | P84022, Q13485, P10415, P42338, P49767, P19174 | SMAD3, SMAD4, BCL2, PIK3CB, VEGFC, PLCG1 | More | | | Oleic-Acid | hsa04934 | Cushing syndrome | 3.48E-03 | 4 | Q99941, P51828, O15169, Q13557 | CREBL1, ADCY7, AXIN1, CAMK2D | More | | | Oleic-Acid | hsa04971 | Gastric acid secretion | 1.48E-02 | 3 | P51828, P15311, Q13557 | ADCY7, VIL2, CAMK2D | More | | | Oleic-Acid | hsa04972 | Pancreatic secretion | 3.86E-02 | 3 | Q14643, P20020, P17252 | ITPR1, ATP2B1, PRKCA | More | | | Oleic-Acid | hsa04975 | Fat digestion and absorption | 3.43E-02 | 1 | O14494 | PLPP1 | More | | | Oleic-Acid | hsa05010 | Alzheimer disease | 2.07E-02 | 7 | Q92542, P05496, P12074, O75460, P01584, O15169, P45880 | NCSTN, ATP5G1, COX6A1, ERN1, IL1B, AXIN1, VDAC2 | More | | | Oleic-Acid | hsa05020 | Prion disease | 1.81E-02 | 7 | P01584, P46531, P11142, P05496, P12074, P45880, Q99941 | IL1B, NOTCH1, HSPA8, ATP5G1, COX6A1, VDAC2, CREBL1 | More | | | Oleic-Acid | hsa05130 | Pathogenic Escherichia coli infection | 7.39E-03 | 4 | Q14247, P56750, O00501, P25116 | CTTN, CLDN17, CLDN5, F2R | More | | | Oleic-Acid | hsa05132 | Salmonella infection | 2.04E-02 | 4 | P25963, Q13489, P10415, Q9BQS8 | NFKBIA, BIRC3, BCL2, FYCO1 | More | | | Oleic-Acid | hsa05133 | Pertussis | 2.41E-02 | 2 | P09871, Q02556 | C1S, IRF8 | More | | | Oleic-Acid | hsa05135 | Yersinia infection | 2.58E-02 | 4 | Q05397, P51812, Q02750, Q96JJ3 | PTK2, RPS6KA3, MAP2K1, ELMO2 | More | | | Oleic-Acid | hsa05145 | Toxoplasmosis | 2.78E-02 | 3 | P25963, P10415, Q13489 | NFKBIA, BCL2, BIRC3 | More | | | Oleic-Acid | hsa05161 | Hepatitis B | 8.49E-03 | 4 | P25963, Q13485, P10415, P84022 | NFKBIA, SMAD4, BCL2, SMAD3 | More | | | Oleic-Acid | hsa05163 | Human cytomegalovirus infection | 3.04E-02 | 5 | P0DP24, Q08828, P23458, P61073, Q99941 | CALM2, ADCY1, JAK1, CXCR4, CREBL1 | More | | | Oleic-Acid | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 1.94E-02 | 4 | P62879, P16298, Q02750, P0CG47 | GNB2, PPP3CB, MAP2K1, UBB | More | | | Oleic-Acid | hsa05170 | Human immunodeficiency virus 1 infection | 8.23E-04 | 5 | Q02750, P62879, P16298, Q05397, P20333 | MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1B | More | | | Oleic-Acid | hsa05200 | Pathways in cancer | 9.46E-03 | 17 | Q13751, P42338, P08238, P19174, P43246, P84022, Q13485, Q13547, P30281, P49767, P43657, P63218, P50151, Q14344, Q7LDG7, O75293, P14784 | LAMB3, PIK3CB, HSP90AB1, PLCG1, MSH2, SMAD3, SMAD4, HDAC1, CCND3, VEGFC, P2RY5, GNG5, GNG10, GNA13, RASGRP2, GADD45B, IL2RB | More | | | Oleic-Acid | hsa05206 | MicroRNAs in cancer | 2.97E-03 | 6 | P15311, P21860, P61978, P46531, P63279, P22105 | VIL2, ERBB3, HNRPK, NOTCH1, UBE2I, TNXB | More | | | Oleic-Acid | hsa05210 | Colorectal cancer | 1.78E-02 | 3 | P84022, Q13485, P10415 | SMAD3, SMAD4, BCL2 | More | | | Oleic-Acid | hsa05212 | Pancreatic cancer | 4.45E-03 | 4 | P42338, P84022, Q13485, O75293 | PIK3CB, SMAD3, SMAD4, GADD45B | More | | | Oleic-Acid | hsa05213 | Endometrial cancer | 3.79E-02 | 2 | O15169, Q02750 | AXIN1, MAP2K1 | More | | | Oleic-Acid | hsa05220 | Chronic myeloid leukemia | 1.44E-03 | 6 | Q13547, Q13485, P25963, P84022, P42338, O75293 | HDAC1, SMAD4, NFKBIA, SMAD3, PIK3CB, GADD45B | More | | | Oleic-Acid | hsa05222 | Small cell lung cancer | 3.77E-03 | 7 | P10826, Q13489, P10415, P25963, Q13077, O00463, P24522 | RARB, BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45A | More | | | Oleic-Acid | hsa05226 | Gastric cancer | 4.33E-03 | 5 | Q02750, O15169, P84022, Q13485, P10415 | MAP2K1, AXIN1, SMAD3, SMAD4, BCL2 | More | | | Oleic-Acid | hsa05415 | Diabetic cardiomyopathy | 3.19E-02 | 7 | P17252, P14598, Q15080, Q16718, O14521, Q16539, P14780 | PRKCA, NCF1, NCF4, NDUFA5, SDHD, MAPK14, MMP9 | More | |
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