| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Nevirapine | hsa00030 | Pentose phosphate pathway | 2.25E-03 | 3 | P60891, P51854, P37837 | PRPS1, TKTL1, TALDO1 | More | | | Nevirapine | hsa00052 | Galactose metabolism | 4.27E-02 | 2 | P06280, O43451 | GLA, MGAM | More | | | Nevirapine | hsa00190 | Oxidative phosphorylation | 8.71E-03 | 3 | Q16718, Q13488, O14521 | NDUFA5, TCIRG1, SDHD | More | | | Nevirapine | hsa00220 | Arginine biosynthesis | 4.76E-03 | 2 | P15104, P49448 | GLUL, GLUD2 | More | | | Nevirapine | hsa00250 | Alanine, aspartate and glutamate metabolism | 4.88E-02 | 1 | P49448 | GLUD2 | More | | | Nevirapine | hsa00471 | D-Glutamine and D-glutamate metabolism | 1.65E-02 | 1 | P49448 | GLUD2 | More | | | Nevirapine | hsa00500 | Starch and sucrose metabolism | 6.17E-03 | 3 | O43451, P46976, P06737 | MGAM, GYG1, PYGL | More | | | Nevirapine | hsa00562 | Inositol phosphate metabolism | 3.69E-02 | 3 | P27987, P19174, P42338 | ITPKB, PLCG1, PIK3CB | More | | | Nevirapine | hsa00600 | Sphingolipid metabolism | 3.76E-02 | 1 | P15289 | ARSA | More | | | Nevirapine | hsa00630 | Glyoxylate and dicarboxylate metabolism | 5.34E-03 | 2 | P40925, P15104 | MDH1, GLUL | More | | | Nevirapine | hsa00670 | One carbon pool by folate | 3.15E-02 | 2 | O95954, Q99707 | FTCD, MTR | More | | | Nevirapine | hsa00730 | Thiamine metabolism | 2.27E-02 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Nevirapine | hsa00740 | Riboflavin metabolism | 4.77E-02 | 1 | P30043 | BLVRB | More | | | Nevirapine | hsa00770 | Pantothenate and CoA biosynthesis | 1.15E-02 | 2 | O95498, Q9NRN7 | VNN2, AASDHPPT | More | | | Nevirapine | hsa00860 | Porphyrin and chlorophyll metabolism | 3.15E-02 | 2 | P36551, P30043 | CPOX, BLVRB | More | | | Nevirapine | hsa00910 | Nitrogen metabolism | 4.88E-02 | 1 | P49448 | GLUD2 | More | | | Nevirapine | hsa00970 | Aminoacyl-tRNA biosynthesis | 2.12E-02 | 1 | P14868 | DARS | More | | | Nevirapine | hsa00983 | Drug metabolism - other enzymes | 3.32E-02 | 3 | P04183, P32320, P05164 | TK1, CDA, MPO | More | | | Nevirapine | hsa01230 | Biosynthesis of amino acids | 3.21E-02 | 4 | P51854, P60891, P05089, P37837 | TKTL1, PRPS1, ARG1, TALDO1 | More | | | Nevirapine | hsa01523 | Antifolate resistance | 1.88E-03 | 4 | P41440, Q92820, P04818, P01375 | SLC19A1, GGH, TYMS, TNF | More | | | Nevirapine | hsa03010 | Ribosome | 7.34E-03 | 6 | P62753, P62829, P62888, P61927, P61513, P36578 | RPS6, RPL23, RPL30, RPL37, RPL37A, RPL4 | More | | | Nevirapine | hsa03013 | RNA transport | 4.55E-08 | 20 | P62826, O14980, P52298, Q09161, O14893, P61326, Q9UBU9, Q9H307, Q7Z3B4, P35658, P63279, P68104, Q14152, O75822, Q14240, Q9BZI7, Q9Y6A5, Q14232, Q06787, P51114 | RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NXF1, PNN, NUP54, NUP214, UBE2I, EEF1A1, EIF3A, EIF3J, EIF4A2, UPF3B, TACC3, EIF2B1, FMR1, FXR1 | More | | | Nevirapine | hsa03015 | mRNA surveillance pathway | 4.81E-02 | 2 | Q9BZI7, O94913 | UPF3B, PCF11 | More | | | Nevirapine | hsa03020 | RNA polymerase | 4.91E-06 | 4 | P30876, P24928, P62487, Q9Y535 | POLR2B, POLR2A, POLR2G, POLR3H | More | | | Nevirapine | hsa03040 | Spliceosome | 4.19E-02 | 5 | Q14562, O60508, P08579, Q01130, O43447 | DHX8, CDC40, SNRPB2, SFRS2, PPIH | More | | | Nevirapine | hsa03050 | Proteasome | 4.83E-02 | 1 | P55036 | PSMD4 | More | | | Nevirapine | hsa03060 | Protein export | 2.65E-03 | 3 | Q15070, P37108, Q15005 | OXA1L, SRP14, SPCS2 | More | | | Nevirapine | hsa03320 | PPAR signaling pathway | 4.33E-02 | 2 | Q6PCB7, Q9UNU6 | SLC27A1, CYP8B1 | More | | | Nevirapine | hsa03430 | Mismatch repair | 4.38E-02 | 1 | P20585 | MSH3 | More | | | Nevirapine | hsa03450 | Non-homologous end-joining | 4.21E-02 | 1 | P13010 | XRCC5 | More | | | Nevirapine | hsa04010 | MAPK signaling pathway | 1.53E-02 | 2 | Q9H2K8, Q12933 | TAOK3, TRAF2 | More | | | Nevirapine | hsa04012 | ErbB signaling pathway | 3.69E-02 | 3 | Q13191, P19174, P42338 | CBLB, PLCG1, PIK3CB | More | | | Nevirapine | hsa04015 | Rap1 signaling pathway | 9.14E-03 | 2 | P06213, O00522 | INSR, KRIT1 | More | | | Nevirapine | hsa04020 | Calcium signaling pathway | 4.83E-02 | 4 | Q08828, P0DP23, P05141, P51828 | ADCY1, CALM1, SLC25A5, ADCY7 | More | | | Nevirapine | hsa04022 | cGMP-PKG signaling pathway | 4.38E-03 | 6 | P18848, P31751, Q08828, P51828, P05141, P0DP23 | ATF4, AKT2, ADCY1, ADCY7, SLC25A5, CALM1 | More | | | Nevirapine | hsa04024 | cAMP signaling pathway | 3.94E-02 | 4 | Q08828, P51828, P31751, P0DP23 | ADCY1, ADCY7, AKT2, CALM1 | More | | | Nevirapine | hsa04060 | Cytokine-cytokine receptor interaction | 2.09E-02 | 8 | P14784, P14778, Q06643, Q13651, Q9HBE5, P09341, P19875, Q93038 | IL2RB, IL1R1, LTB, IL10RA, IL21R, CXCL1, CXCL2, TNFRSF25 | More | | | Nevirapine | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 4.54E-02 | 2 | Q8NHW4, Q13651 | CCL4L2, IL10RA | More | | | Nevirapine | hsa04064 | NF-kappa B signaling pathway | 1.72E-08 | 23 | P10415, Q13489, O00463, Q13546, P14778, P01584, P01375, P29965, P19174, Q04759, Q9UDY8, Q16548, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9UNE0, Q9NQC7 | BCL2, BIRC3, TRAF5, RIPK1, IL1R1, IL1B, TNF, CD40LG, PLCG1, PRKCQ, MALT1, BCL2A1, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, EDAR, CYLD | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P17252 | PRKCA | Protein kinase C alpha type | P10415 | BCL2 | Apoptosis regulator Bcl-2 | 0.844 | | P17252 | PRKCA | Protein kinase C alpha type | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.849 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | Q04759 | PRKCQ | Protein kinase C theta type | O00463 | TRAF5 | TNF receptor-associated factor 5 | 0.81 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P24723 | PRKCH | Protein kinase C eta type | P14778 | IL1R1 | Interleukin-1 receptor type 1 | -0.705 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | P01584 | IL1B | Interleukin-1 beta | 0.799 | | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | P01584 | IL1B | Interleukin-1 beta | 0.735 | | Q04759 | PRKCQ | Protein kinase C theta type | P01375 | TNF | Tumor necrosis factor | -0.725 | | P17252 | PRKCA | Protein kinase C alpha type | P29965 | CD40LG | CD40 ligand | 0.788 | | P24723 | PRKCH | Protein kinase C eta type | P19174 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | 0.767 | | Q04759 | PRKCQ | Protein kinase C theta type | Q04759 | PRKCQ | Protein kinase C theta type | 1 | | P24723 | PRKCH | Protein kinase C eta type | Q04759 | PRKCQ | Protein kinase C theta type | 0.791 | | P17252 | PRKCA | Protein kinase C alpha type | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.769 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | Q04759 | PRKCQ | Protein kinase C theta type | Q16548 | BCL2A1 | Bcl-2-related protein A1 | -0.76 | | Q04759 | PRKCQ | Protein kinase C theta type | P06239 | LCK | Tyrosine-protein kinase Lck | 0.779 | | P24723 | PRKCH | Protein kinase C eta type | P06239 | LCK | Tyrosine-protein kinase Lck | 0.912 | | P17252 | PRKCA | Protein kinase C alpha type | Q8WV28 | BLNK | B-cell linker protein | 0.838 | | P17252 | PRKCA | Protein kinase C alpha type | Q13315 | ATM | Serine-protein kinase ATM | 0.739 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | P63279 | UBE2I | SUMO-conjugating enzyme UBC9 | 0.756 | | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | P63279 | UBE2I | SUMO-conjugating enzyme UBC9 | 0.739 | | Q04759 | PRKCQ | Protein kinase C theta type | P24522 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | -0.846 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.802 | | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.756 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.802 | | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | Q8NHW4 | CCL4L2 | C-C motif chemokine 4-like | 0.756 | | Q04759 | PRKCQ | Protein kinase C theta type | P09341 | CXCL1 | Growth-regulated alpha protein | -0.885 | | P24723 | PRKCH | Protein kinase C eta type | P09341 | CXCL1 | Growth-regulated alpha protein | -0.707 | | P24723 | PRKCH | Protein kinase C eta type | P19875 | CXCL2 | C-X-C motif chemokine 2 | -0.853 | | P24723 | PRKCH | Protein kinase C eta type | Q06643 | LTB | Lymphotoxin-beta | 0.763 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 | | P23458 | JAK1 | Tyrosine-protein kinase JAK1 | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.825 | | Q00535 | CDK5 | Cyclin-dependent-like kinase 5 | Q9NQC7 | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD | 0.753 |
| | Nevirapine | hsa04070 | Phosphatidylinositol signaling system | 8.69E-05 | 9 | P0DP23, Q14643, O14986, P23743, Q86XP1, Q16760, P48426, Q96DU7, P17252 | CALM1, ITPR1, PIP5K1B, DGKA, DGKH, DGKD, PIP4K2A, ITPKC, PRKCA | More | | | Nevirapine | hsa04071 | Sphingolipid signaling pathway | 1.29E-03 | 8 | P17252, Q9H228, P01375, Q13362, Q9BX95, P10415, Q12933, Q02156 | PRKCA, EDG8, TNF, PPP2R5C, SGPP1, BCL2, TRAF2, PRKCE | More | | | Nevirapine | hsa04072 | Phospholipase D signaling pathway | 2.40E-03 | 6 | P31751, O14986, Q15438, Q08828, P51828, Q16760 | AKT2, PIP5K1B, PSCD1, ADCY1, ADCY7, DGKD | More | | | Nevirapine | hsa04110 | Cell cycle | 6.63E-04 | 6 | P06493, O60566, P30304, P33981, P42773, P01106 | CDK1, BUB1B, CDC25A, TTK, CDKN2C, MYC | More | | | Nevirapine | hsa04114 | Oocyte meiosis | 2.55E-04 | 10 | Q9Y6D9, P51812, Q02750, P0DP23, P16298, Q17RY0, Q08828, P51828, Q13362, Q14738 | MAD1L1, RPS6KA3, MAP2K1, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, PPP2R5C, PPP2R5D | More | | | Nevirapine | hsa04120 | Ubiquitin mediated proteolysis | 1.08E-03 | 6 | Q9UBT2, Q14145, Q13042, P62837, Q15751, Q14669 | SAE2, KEAP1, CDC16, UBE2D2, HERC1, TRIP12 | More | | | Nevirapine | hsa04140 | Autophagy - animal | 7.93E-04 | 9 | Q9Y4H2, P42338, P31751, Q7L523, Q9NQL2, O75460, Q04759, Q96GC9, Q8TEV9 | IRS2, PIK3CB, AKT2, RRAGA, RRAGD, ERN1, PRKCQ, TMEM49, SMCR8 | More | | | Nevirapine | hsa04142 | Lysosome | 1.46E-02 | 7 | P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916 | HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2 | More | | | Nevirapine | hsa04144 | Endocytosis | 1.67E-02 | 8 | P0DMV8, Q9H444, O75351, P62491, Q96B97, Q15438, Q14161, Q9UMY4 | HSPA1A, CHMP4B, VPS4B, RAB11A, SH3KBP1, PSCD1, GIT2, SNX12 | More | | | Nevirapine | hsa04145 | Phagosome | 1.59E-03 | 7 | Q15080, P14598, Q13509, P68371, Q13488, O60603, P13765 | NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, TLR2, HLA-DOB | More | | | Nevirapine | hsa04151 | PI3K-Akt signaling pathway | 4.50E-02 | 9 | P25116, P49767, Q13362, P62873, P16144, O60603, P01568, P10415, P17252 | F2R, VEGFC, PPP2R5C, GNB1, ITGB4, TLR2, IFNA21, BCL2, PRKCA | More | | | Nevirapine | hsa04152 | AMPK signaling pathway | 2.34E-02 | 2 | Q96EB6, P36956 | SIRT1, SREBF1 | More | | | Nevirapine | hsa04211 | Longevity regulating pathway | 9.34E-04 | 7 | Q12778, P31751, Q08828, P51828, P18848, Q9UEF7, Q96KQ7 | FOXO1, AKT2, ADCY1, ADCY7, ATF4, KL, EHMT2 | More | | | Nevirapine | hsa04213 | Longevity regulating pathway - multiple species | 1.40E-04 | 8 | P31751, P42338, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547 | AKT2, PIK3CB, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1 | More | | | Nevirapine | hsa04217 | Necroptosis | 6.42E-07 | 17 | P01375, P01568, P48023, Q13489, Q9NQC7, Q13546, P42224, Q14765, P07900, P15104, P01584, Q6FI13, Q99878, P10415, Q9H444, O43633, Q08752 | TNF, IFNA21, FASLG, BIRC3, CYLD, RIPK1, STAT1, STAT4, HSP90AA1, GLUL, IL1B, H2AC18; H2AC19, H2AC14, BCL2, CHMP4B, CHMP2A, PPID | More | | | Nevirapine | hsa04261 | Adrenergic signaling in cardiomyocytes | 7.03E-05 | 10 | P09493, Q08828, P51828, P31751, P18848, Q13362, Q14738, P0DP23, P17252, P10415 | TPM1, ADCY1, ADCY7, AKT2, ATF4, PPP2R5C, PPP2R5D, CALM1, PRKCA, BCL2 | More | | | Nevirapine | hsa04270 | Vascular smooth muscle contraction | 6.96E-03 | 6 | P0DP23, Q08828, P51828, P35579, P35749, P35318 | CALM1, ADCY1, ADCY7, MYH9, MYH11, ADM | More | | | Nevirapine | hsa04370 | VEGF signaling pathway | 3.02E-04 | 5 | P19174, P16298, P42338, Q05397, Q02750 | PLCG1, PPP3CB, PIK3CB, PTK2, MAP2K1 | More | | | Nevirapine | hsa04371 | Apelin signaling pathway | 3.94E-02 | 4 | P31751, Q08828, P51828, P0DP23 | AKT2, ADCY1, ADCY7, CALM1 | More | | | Nevirapine | hsa04380 | Osteoclast differentiation | 5.27E-04 | 10 | Q9NQC7, Q9UQC2, Q16539, P23458, P31751, P01584, P14778, O75015, P01375, Q8N149 | CYLD, GAB2, MAPK14, JAK1, AKT2, IL1B, IL1R1, FCGR3B, TNF, LILRA2 | More | | | Nevirapine | hsa04540 | Gap junction | 1.29E-02 | 4 | P17252, Q13509, P68371, Q14643 | PRKCA, TUBB3, TUBB2C, ITPR1 | More | | | Nevirapine | hsa04612 | Antigen processing and presentation | 1.74E-03 | 9 | P13765, P26715, P26717, Q07444, Q13241, P01732, P30101, P11142, P01375 | HLA-DOB, KLRC1, KLRC2, KLRC3, KLRD1, CD8A, PDIA3, HSPA8, TNF | More | | | Nevirapine | hsa04613 | Neutrophil extracellular trap formation | 3.58E-02 | 8 | P17252, O60603, P08246, Q6FI13, P68431, P14598, Q15080, P21462 | PRKCA, TLR2, ELA2, H2AC18; H2AC19, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1 | More | | | Nevirapine | hsa04620 | Toll-like receptor signaling pathway | 4.30E-04 | 5 | Q13546, P01568, P01584, P31751, Q8NHW4 | RIPK1, IFNA21, IL1B, AKT2, CCL4L2 | More | | | Nevirapine | hsa04621 | NOD-like receptor signaling pathway | 5.27E-04 | 13 | P01584, P07900, Q14643, P01568, Q13489, P10599, P43490, O00463, Q13546, P29728, P01375, P09341, P12838 | IL1B, HSP90AA1, ITPR1, IFNA21, BIRC3, TXN, PBEF1, TRAF5, RIPK1, OAS2, TNF, CXCL1, DEFA4 | More | | | Nevirapine | hsa04622 | RIG-I-like receptor signaling pathway | 1.28E-03 | 3 | P01568, Q13546, Q12933 | IFNA21, RIPK1, TRAF2 | More | | | Nevirapine | hsa04623 | Cytosolic DNA-sensing pathway | 4.19E-08 | 5 | P01584, P01568, Q13546, Q9Y535, Q8NHW4 | IL1B, IFNA21, RIPK1, POLR3H, CCL4L2 | More | | | Nevirapine | hsa04625 | C-type lectin receptor signaling pathway | 1.14E-03 | 8 | Q9ULY5, P01584, Q9NQC7, P20749, P01375, P31751, P0DP23, Q16539 | CLEC4E, IL1B, CYLD, BCL3, TNF, AKT2, CALM1, MAPK14 | More | | | Nevirapine | hsa04630 | JAK-STAT signaling pathway | 4.54E-02 | 3 | P31751, P23458, Q13651 | AKT2, JAK1, IL10RA | More | | | Nevirapine | hsa04640 | Hematopoietic cell lineage | 2.36E-04 | 12 | P14778, P27930, P11215, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375 | IL1R1, IL1R2, ITGAM, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF | More | | | Nevirapine | hsa04650 | Natural killer cell mediated cytotoxicity | 1.58E-07 | 15 | P16298, P50591, P19174, P01375, P06239, O60880, P20963, P42338, Q02750, Q13241, P26718, O14931, P26717, Q07444, P26715 | PPP3CB, TNFSF10, PLCG1, TNF, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, KLRD1, KLRK1, NCR3, KLRC2, KLRC3, KLRC1 | More | | | Nevirapine | hsa04657 | IL-17 signaling pathway | 7.99E-04 | 7 | P07900, O00463, Q16539, P49841, P14780, P01375, P01584 | HSP90AA1, TRAF5, MAPK14, GSK3B, MMP9, TNF, IL1B | More | | | Nevirapine | hsa04658 | Th1 and Th2 cell differentiation | 1.04E-08 | 12 | Q04759, P07766, P20963, P09693, P19174, P06239, Q14765, P23771, Q9UL17, P14784, P13765, Q13761 | PRKCQ, CD3E, CD247, CD3G, PLCG1, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3 | More | | | Nevirapine | hsa04659 | Th17 cell differentiation | 7.86E-08 | 12 | Q04759, P19174, P06239, P14784, P13765, P14778, Q9HBE5, Q9UL17, P23771, P07766, P09693, P20963 | PRKCQ, PLCG1, LCK, IL2RB, HLA-DOB, IL1R1, IL21R, TBX21, GATA3, CD3E, CD3G, CD247 | More | | | Nevirapine | hsa04660 | T cell receptor signaling pathway | 8.92E-07 | 12 | P01375, Q04759, P42338, O95267, Q08881, P19174, P07766, P20963, P09693, P01732, Q13191, P06239 | TNF, PRKCQ, PIK3CB, RASGRP1, ITK, PLCG1, CD3E, CD247, CD3G, CD8A, CBLB, LCK | More | | | Nevirapine | hsa04662 | B cell receptor signaling pathway | 1.05E-04 | 5 | P42338, P60033, P07948, P21854, Q8N149 | PIK3CB, CD81, LYN, CD72, LILRA2 | More | | | Nevirapine | hsa04664 | Fc epsilon RI signaling pathway | 2.20E-03 | 6 | P01375, Q16539, P42338, Q9UQC2, P07948, P09917 | TNF, MAPK14, PIK3CB, GAB2, LYN, ALOX5 | More | | | Nevirapine | hsa04668 | TNF signaling pathway | 2.21E-02 | 5 | P01375, O00463, Q16539, P20749, P14780 | TNF, TRAF5, MAPK14, BCL3, MMP9 | More | | | Nevirapine | hsa04672 | Intestinal immune network for IgA production | 3.76E-03 | 3 | P29965, P10747, P13765 | CD40LG, CD28, HLA-DOB | More | | | Nevirapine | hsa04710 | Circadian rhythm | 4.40E-02 | 1 | O15516 | CLOCK | More | | | Nevirapine | hsa04713 | Circadian entrainment | 2.85E-03 | 6 | P0DP23, P17252, P62873, Q14643, Q08828, P51828 | CALM1, PRKCA, GNB1, ITPR1, ADCY1, ADCY7 | More | | | Nevirapine | hsa04720 | Long-term potentiation | 3.88E-04 | 8 | P17252, P16298, P0DP23, P51812, P18848, Q08828, Q02750, Q14643 | PRKCA, PPP3CB, CALM1, RPS6KA3, ATF4, ADCY1, MAP2K1, ITPR1 | More | | | Nevirapine | hsa04722 | Neurotrophin signaling pathway | 1.98E-03 | 5 | Q05655, P49841, O43524, P48023, P52566 | PRKCD, GSK3B, FOXO3, FASLG, ARHGDIB | More | | | Nevirapine | hsa04723 | Retrograde endocannabinoid signaling | 1.88E-02 | 4 | Q14643, P17252, P62873, Q16718 | ITPR1, PRKCA, GNB1, NDUFA5 | More | | | Nevirapine | hsa04724 | Glutamatergic synapse | 5.94E-03 | 4 | O15399, P63218, P50151, P15104 | GRIN2D, GNG5, GNG10, GLUL | More | | | Nevirapine | hsa04725 | Cholinergic synapse | 7.72E-05 | 11 | Q08828, P51828, Q14643, P17252, P62873, P63218, P50151, P18848, P42338, P31751, P10415 | ADCY1, ADCY7, ITPR1, PRKCA, GNB1, GNG5, GNG10, ATF4, PIK3CB, AKT2, BCL2 | More | | | Nevirapine | hsa04727 | GABAergic synapse | 1.63E-02 | 3 | P63218, P50151, P15104 | GNG5, GNG10, GLUL | More | | | Nevirapine | hsa04728 | Dopaminergic synapse | 9.19E-04 | 8 | Q14643, P17252, P62873, P31751, P18848, Q13362, Q14738, P0DP23 | ITPR1, PRKCA, GNB1, AKT2, ATF4, PPP2R5C, PPP2R5D, CALM1 | More | | | Nevirapine | hsa04740 | Olfactory transduction | 2.52E-02 | 1 | Q9H255 | OR51E2 | More | | | Nevirapine | hsa04742 | Taste transduction | 1.01E-02 | 1 | P30939 | HTR1F | More | | | Nevirapine | hsa04744 | Phototransduction | 1.02E-02 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | | | Nevirapine | hsa04750 | Inflammatory mediator regulation of TRP channels | 8.88E-06 | 9 | P14778, P01584, Q08828, P51828, P19174, P42338, P24723, Q04759, P0DP23 | IL1R1, IL1B, ADCY1, ADCY7, PLCG1, PIK3CB, PRKCH, PRKCQ, CALM1 | More | | | Nevirapine | hsa04911 | Insulin secretion | 2.40E-02 | 3 | Q08828, P51828, P18848 | ADCY1, ADCY7, ATF4 | More | | | Nevirapine | hsa04912 | GnRH signaling pathway | 1.52E-03 | 6 | P17252, Q08828, P51828, P18848, Q14643, P0DP23 | PRKCA, ADCY1, ADCY7, ATF4, ITPR1, CALM1 | More | | | Nevirapine | hsa04913 | Ovarian steroidogenesis | 2.52E-02 | 1 | P06213 | INSR | More | | | Nevirapine | hsa04914 | Progesterone-mediated oocyte maturation | 1.00E-02 | 4 | Q17RY0, Q9Y6D9, P51812, Q02750 | CPEB4, MAD1L1, RPS6KA3, MAP2K1 | More | | | Nevirapine | hsa04915 | Estrogen signaling pathway | 2.01E-03 | 7 | P18848, Q08828, P51828, P31751, P0DMV8, P0DP23, Q15788 | ATF4, ADCY1, ADCY7, AKT2, HSPA1A, CALM1, NCOA1 | More | | | Nevirapine | hsa04916 | Melanogenesis | 2.40E-02 | 3 | P0DP23, Q08828, P51828 | CALM1, ADCY1, ADCY7 | More | | | Nevirapine | hsa04922 | Glucagon signaling pathway | 3.47E-02 | 4 | Q12778, Q13370, P0DP23, Q14643 | FOXO1, PDE3B, CALM1, ITPR1 | More | | | Nevirapine | hsa04923 | Regulation of lipolysis in adipocytes | 7.59E-04 | 4 | Q08828, P51828, P06213, P31751 | ADCY1, ADCY7, INSR, AKT2 | More | | | Nevirapine | hsa04924 | Renin secretion | 8.71E-03 | 3 | Q14643, Q13370, P0DP23 | ITPR1, PDE3B, CALM1 | More | | | Nevirapine | hsa04925 | Aldosterone synthesis and secretion | 9.86E-03 | 4 | P18848, Q08828, P51828, P0DP23 | ATF4, ADCY1, ADCY7, CALM1 | More | | | Nevirapine | hsa04926 | Relaxin signaling pathway | 3.95E-04 | 9 | P31751, P42338, P63218, P50151, P18848, P49767, Q08828, P51828, P49407 | AKT2, PIK3CB, GNG5, GNG10, ATF4, VEGFC, ADCY1, ADCY7, ARRB1 | More | | | Nevirapine | hsa04927 | Cortisol synthesis and secretion | 1.59E-02 | 3 | P18848, Q08828, P51828 | ATF4, ADCY1, ADCY7 | More | | | Nevirapine | hsa04929 | GnRH secretion | 4.62E-02 | 2 | P42338, P49407 | PIK3CB, ARRB1 | More | | | Nevirapine | hsa04930 | Type II diabetes mellitus | 6.29E-05 | 3 | P06213, Q05655, Q02156 | INSR, PRKCD, PRKCE | More | | | Nevirapine | hsa04932 | Non-alcoholic fatty liver disease | 3.12E-06 | 12 | P31751, P01375, P49841, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, O95298 | AKT2, TNF, GSK3B, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFC2 | More | | | Nevirapine | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 1.27E-02 | 5 | P42224, P10415, Q12778, P49767, P17252 | STAT1, BCL2, FOXO1, VEGFC, PRKCA | More | | | Nevirapine | hsa04934 | Cushing syndrome | 4.54E-02 | 3 | P18848, Q08828, P51828 | ATF4, ADCY1, ADCY7 | More | | | Nevirapine | hsa04935 | Growth hormone synthesis, secretion and action | 1.88E-02 | 4 | Q08828, P51828, P18848, P31751 | ADCY1, ADCY7, ATF4, AKT2 | More | | | Nevirapine | hsa04940 | Type I diabetes mellitus | 1.87E-02 | 2 | P48023, P01375 | FASLG, TNF | More | | | Nevirapine | hsa04960 | Aldosterone-regulated sodium reabsorption | 7.59E-03 | 2 | O00141, P06213 | SGK, INSR | More | | | Nevirapine | hsa04964 | Proximal tubule bicarbonate reclamation | 4.88E-02 | 1 | P49448 | GLUD2 | More | | | Nevirapine | hsa04966 | Collecting duct acid secretion | 2.86E-02 | 2 | Q13488, Q9Y666 | TCIRG1, SLC12A7 | More | | | Nevirapine | hsa04970 | Salivary secretion | 1.89E-03 | 3 | Q08828, P51828, P0DP23 | ADCY1, ADCY7, CALM1 | More | | | Nevirapine | hsa04971 | Gastric acid secretion | 2.54E-03 | 4 | Q08828, P51828, P15311, P0DP23 | ADCY1, ADCY7, VIL2, CALM1 | More | | | Nevirapine | hsa04974 | Protein digestion and absorption | 2.47E-02 | 1 | Q7Z2H8 | SLC36A1 | More | | | Nevirapine | hsa04975 | Fat digestion and absorption | 2.80E-02 | 1 | O14494 | PLPP1 | More | | | Nevirapine | hsa04976 | Bile secretion | 1.89E-03 | 3 | Q08828, P51828, Q14032 | ADCY1, ADCY7, BAAT | More | | | Nevirapine | hsa05010 | Alzheimer disease | 7.57E-04 | 15 | Q16718, O95298, O14521, Q14643, Q00535, O75460, P0DP23, P01584, P18848, Q13509, P68371, P31751, P05141, Q08752, P28070 | NDUFA5, NDUFC2, SDHD, ITPR1, CDK5, ERN1, CALM1, IL1B, ATF4, TUBB3, TUBB2C, AKT2, SLC25A5, PPID, PSMB4 | More | | | Nevirapine | hsa05012 | Parkinson disease | 2.25E-02 | 6 | Q16718, O14521, Q14643, P0DP23, Q13509, P68371 | NDUFA5, SDHD, ITPR1, CALM1, TUBB3, TUBB2C | More | | | Nevirapine | hsa05016 | Huntington disease | 1.76E-03 | 10 | O95298, P13073, P12074, P24928, P30876, P62487, P05141, O75460, P28070, O00232 | NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, SLC25A5, ERN1, PSMB4, PSMD12 | More | | | Nevirapine | hsa05017 | Spinocerebellar ataxia | 3.94E-02 | 4 | O75460, P31751, P28070, P05141 | ERN1, AKT2, PSMB4, SLC25A5 | More | | | Nevirapine | hsa05020 | Prion disease | 1.15E-02 | 7 | Q16718, O14521, Q14643, Q13509, P68371, P14598, Q15080 | NDUFA5, SDHD, ITPR1, TUBB3, TUBB2C, NCF1, NCF4 | More | | | Nevirapine | hsa05022 | Pathways of neurodegeneration - multiple diseases | 3.36E-04 | 18 | Q14643, Q13509, P68371, P10415, Q16718, O95298, O14521, Q8TEV9, O75460, P18848, Q13561, P05141, P17252, Q00535, P01584, Q08752, P0DP23, P28070 | ITPR1, TUBB3, TUBB2C, BCL2, NDUFA5, NDUFC2, SDHD, SMCR8, ERN1, ATF4, DCTN2, SLC25A5, PRKCA, CDK5, IL1B, PPID, CALM1, PSMB4 | More | | | Nevirapine | hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 4.95E-02 | 3 | P09341, P19875, P19174 | CXCL1, CXCL2, PLCG1 | More | | | Nevirapine | hsa05131 | Shigellosis | 4.98E-04 | 12 | Q12933, P68431, Q05655, Q02156, Q9UDY8, Q14247, Q14643, Q12778, Q13315, P10415, Q08752, P07737 | TRAF2, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, PRKCD, PRKCE, MALT1, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID, PFN1 | More | | | Nevirapine | hsa05132 | Salmonella infection | 2.53E-04 | 12 | Q9UJU2, P84095, Q13546, Q13489, P10415, P07737, O60603, Q9BQS8, Q13561, O60282, Q13509, P68371 | LEF1, RHOG, RIPK1, BIRC3, BCL2, PFN1, TLR2, FYCO1, DCTN2, KIF5C, TUBB3, TUBB2C | More | | | Nevirapine | hsa05134 | Legionellosis | 3.59E-04 | 7 | P01584, Q9NR31, P11215, P0DMV8, P11142, P09341, P19875 | IL1B, SAR1A, ITGAM, HSPA1A, HSPA8, CXCL1, CXCL2 | More | | | Nevirapine | hsa05135 | Yersinia infection | 4.25E-03 | 8 | Q05397, P51812, P06239, P19174, Q02750, P42338, Q96JJ3, P01732 | PTK2, RPS6KA3, LCK, PLCG1, MAP2K1, PIK3CB, ELMO2, CD8A | More | | | Nevirapine | hsa05140 | Leishmaniasis | 2.17E-03 | 6 | P14598, P42224, P13765, O60603, P29350, Q15080 | NCF1, STAT1, HLA-DOB, TLR2, PTPN6, NCF4 | More | | | Nevirapine | hsa05143 | African trypanosomiasis | 2.72E-02 | 2 | P01375, P48023 | TNF, FASLG | More | | | Nevirapine | hsa05145 | Toxoplasmosis | 1.11E-02 | 6 | P10415, Q13489, P42224, P13765, O60603, P29965 | BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LG | More | | | Nevirapine | hsa05146 | Amoebiasis | 6.56E-07 | 11 | P09341, P19875, P14778, P27930, P01375, P42338, P11215, P05089, P22694, P12814, P08311 | CXCL1, CXCL2, IL1R1, IL1R2, TNF, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSG | More | | | Nevirapine | hsa05152 | Tuberculosis | 7.93E-04 | 8 | Q13488, P0DP23, P42224, O60603, P10415, P13765, P01568, Q9UDY8 | TCIRG1, CALM1, STAT1, TLR2, BCL2, HLA-DOB, IFNA21, MALT1 | More | | | Nevirapine | hsa05160 | Hepatitis C | 1.27E-02 | 4 | P60033, P49841, P01375, P48023 | CD81, GSK3B, TNF, FASLG | More | | | Nevirapine | hsa05162 | Measles | 3.18E-02 | 4 | P23458, P0DMV8, P01584, Q9NP90 | JAK1, HSPA1A, IL1B, RAB9B | More | | | Nevirapine | hsa05163 | Human cytomegalovirus infection | 2.69E-06 | 15 | P31751, P01375, P0DP23, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, P18848, O00463 | AKT2, TNF, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, ATF4, TRAF5 | More | | | Nevirapine | hsa05164 | Influenza A | 4.49E-02 | 5 | P31751, P01584, P23458, P05141, Q9UBU9 | AKT2, IL1B, JAK1, SLC25A5, NXF1 | More | | | Nevirapine | hsa05165 | Human papillomavirus infection | 3.10E-02 | 8 | P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315 | ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATM | More | | | Nevirapine | hsa05166 | Human T-cell leukemia virus 1 infection | 3.90E-02 | 7 | P23458, P05141, P62826, Q08828, P51828, P18848, P31751 | JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2 | More | | | Nevirapine | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 5.29E-03 | 10 | P01568, P42224, P62873, P62879, P16298, Q14643, Q02750, P0DP23, P0CG47, Q9UJU2 | IFNA21, STAT1, GNB1, GNB2, PPP3CB, ITPR1, MAP2K1, CALM1, UBB, LEF1 | More | | | Nevirapine | hsa05169 | Epstein-Barr virus infection | 3.69E-03 | 13 | P13765, Q13547, O00463, P42338, P07948, Q13761, P24522, O75293, P01375, P29728, P07766, P09693, P20963 | HLA-DOB, HDAC1, TRAF5, PIK3CB, LYN, RUNX3, GADD45A, GADD45B, TNF, OAS2, CD3E, CD3G, CD247 | More | | | Nevirapine | hsa05170 | Human immunodeficiency virus 1 infection | 4.67E-03 | 9 | P62873, P0DP23, P17252, Q14643, P01568, O60603, Q13315, P10415, Q9Y6Q5 | GNB1, CALM1, PRKCA, ITPR1, IFNA21, TLR2, ATM, BCL2, AP1M2 | More | | | Nevirapine | hsa05171 | Coronavirus disease - COVID-19 | 3.18E-03 | 7 | P01584, P62753, P36578, P62888, P61927, P61513, P62829 | IL1B, RPS6, RPL4, RPL30, RPL37, RPL37A, RPL23 | More | | | Nevirapine | hsa05200 | Pathways in cancer | 4.99E-02 | 12 | P42224, Q9UJU2, P17252, P14923, P10415, Q13489, P49767, Q12778, P25116, P62873, P0DP23, P01568 | STAT1, LEF1, PRKCA, JUP, BCL2, BIRC3, VEGFC, FOXO1, F2R, GNB1, CALM1, IFNA21 | More | | | Nevirapine | hsa05202 | Transcriptional misregulation in cancer | 3.92E-02 | 10 | P14780, P27930, Q15744, Q16548, P05164, P12838, P08246, Q9C0K0, Q13547, P24522 | MMP9, IL1R2, CEBPE, BCL2A1, MPO, DEFA4, ELA2, BCL11B, HDAC1, GADD45A | More | | | Nevirapine | hsa05212 | Pancreatic cancer | 2.40E-02 | 3 | P31751, Q15311, P23458 | AKT2, RALBP1, JAK1 | More | | | Nevirapine | hsa05221 | Acute myeloid leukemia | 4.95E-02 | 3 | P42338, Q15744, P11215 | PIK3CB, CEBPE, ITGAM | More | | | Nevirapine | hsa05231 | Choline metabolism in cancer | 3.38E-02 | 3 | P31751, Q16760, O14986 | AKT2, DGKD, PIP5K1B | More | | | Nevirapine | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 1.34E-04 | 8 | P42338, O95267, P19174, P07766, P20963, P09693, P06239, Q04759 | PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PRKCQ | More | | | Nevirapine | hsa05310 | Asthma | 8.13E-03 | 3 | P13765, P12724, P01375 | HLA-DOB, RNASE3, TNF | More | | | Nevirapine | hsa05320 | Autoimmune thyroid disease | 1.27E-03 | 4 | P13765, P29965, P01568, P10747 | HLA-DOB, CD40LG, IFNA21, CD28 | More | | | Nevirapine | hsa05321 | Inflammatory bowel disease | 2.80E-04 | 6 | P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5 | TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21R | More | | | Nevirapine | hsa05322 | Systemic lupus erythematosus | 4.18E-03 | 7 | P08246, P09871, P10747, P13765, P29965, Q6FI13, P68431 | ELA2, C1S, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | | | Nevirapine | hsa05323 | Rheumatoid arthritis | 1.59E-03 | 7 | Q06643, P13765, Q13488, P10747, P09341, P19875, O60603 | LTB, HLA-DOB, TCIRG1, CD28, CXCL1, CXCL2, TLR2 | More | | | Nevirapine | hsa05330 | Allograft rejection | 1.04E-03 | 5 | P13765, P29965, P48023, P10747, P01375 | HLA-DOB, CD40LG, FASLG, CD28, TNF | More | | | Nevirapine | hsa05332 | Graft-versus-host disease | 7.35E-04 | 5 | P13765, P48023, P01375, P26715, Q13241 | HLA-DOB, FASLG, TNF, KLRC1, KLRD1 | More | | | Nevirapine | hsa05340 | Primary immunodeficiency | 4.95E-02 | 3 | P01732, P07766, P06239 | CD8A, CD3E, LCK | More | | | Nevirapine | hsa05415 | Diabetic cardiomyopathy | 3.55E-02 | 5 | P17252, P14598, Q15080, Q16718, O14521 | PRKCA, NCF1, NCF4, NDUFA5, SDHD | More | | | Nevirapine | hsa05416 | Viral myocarditis | 2.62E-02 | 3 | P13765, P29965, P10747 | HLA-DOB, CD40LG, CD28 | More | | | Nevirapine | hsa05418 | Fluid shear stress and atherosclerosis | 1.08E-03 | 7 | Q16539, Q14145, P10599, P14780, P01375, P14778, P27930 | MAPK14, KEAP1, TXN, MMP9, TNF, IL1R1, IL1R2 | More | |
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