PharmaCoNets of Nadh (SPCN: 125.24 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
NADHhsa00010Glycolysis / Gluconeogenesis4.41E-024P04075, P06733, P04406, P60174ALDOA, ENO1, GAPDH, TPI1More
NADHhsa00030Pentose phosphate pathway2.89E-045P60891, P51854, P08237, P11413, P37837PRPS1, TKTL1, PFKM, G6PD, TALDO1More
NADHhsa00040Pentose and glucuronate interconversions2.60E-044Q9UEF7, P15121, O60701, P14550KL, AKR1B1, UGDH, AKR1A1More
NADHhsa00051Fructose and mannose metabolism2.21E-023O14772, P60174, P04075FPGT, TPI1, ALDOAMore
NADHhsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
NADHhsa00053Ascorbate and aldarate metabolism4.26E-063P51648, P14550, Q9UEF7ALDH3A2, AKR1A1, KLMore
NADHhsa00071Fatty acid degradation7.45E-043P11310, P28332, P33121ACADM, ADH6, ACSL1More
NADHhsa00120Primary bile acid biosynthesis3.01E-021P51659HSD17B4More
NADHhsa00190Oxidative phosphorylation2.34E-033Q16718, Q13488, O14521NDUFA5, TCIRG1, SDHDMore
NADHhsa00220Arginine biosynthesis2.50E-073P15104, P05089, P49448GLUL, ARG1, GLUD2More
NADHhsa00250Alanine, aspartate and glutamate metabolism7.44E-043P51649, P49448, P15104ALDH5A1, GLUD2, GLULMore
NADHhsa00270Cysteine and methionine metabolism4.70E-023Q99707, P26358, Q9UHY7MTR, DNMT1, ENOPH1More
NADHhsa00280Valine, leucine and isoleucine degradation1.12E-076P21953, P55809, Q9HCC0, P51648, Q02252, P11310BCKDHB, OXCT1, MCCC2, ALDH3A2, ALDH6A1, ACADMMore
NADHhsa00310Lysine degradation1.10E-042Q96KQ7, P51648EHMT2, ALDH3A2More
NADHhsa00471D-Glutamine and D-glutamate metabolism1.65E-021P49448GLUD2More
NADHhsa00480Glutathione metabolism2.60E-055Q9UJ14, P11413, Q16772, P09211, P30041GGTL3, G6PD, GSTA3, GSTP1, PRDX6More
NADHhsa00500Starch and sucrose metabolism1.11E-053O43451, P46976, P06737MGAM, GYG1, PYGLMore
NADHhsa00512Mucin type O-glycan biosynthesis2.19E-022O95395, Q8N4A0GCNT3, GALNT4More
NADHhsa00531Glycosaminoglycan degradation3.03E-021P15586GNSMore
NADHhsa00533Glycosaminoglycan biosynthesis - keratan sulfate2.92E-021Q9NY97B3GNT2More
NADHhsa00561Glycerolipid metabolism2.74E-045P15121, P51648, P14550, P23743, Q86XP1AKR1B1, ALDH3A2, AKR1A1, DGKA, DGKHMore
NADHhsa00564Glycerophospholipid metabolism3.51E-022Q6P1A2, P23743MBOAT5, DGKAMore
NADHhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
NADHhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
NADHhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
NADHhsa00620Pyruvate metabolism3.19E-022P40926, P14550MDH2, AKR1A1More
NADHhsa00630Glyoxylate and dicarboxylate metabolism7.74E-052P40925, P15104MDH1, GLULMore
NADHhsa00670One carbon pool by folate5.86E-043O95954, P00374, Q99707FTCD, DHFR, MTRMore
NADHhsa00730Thiamine metabolism1.66E-032P05186, P24666ALPL, ACP1More
NADHhsa00770Pantothenate and CoA biosynthesis4.92E-043O95498, Q9NRN7, P51648VNN2, AASDHPPT, ALDH3A2More
NADHhsa00790Folate biosynthesis7.39E-044P00374, Q92820, P05186, P42330DHFR, GGH, ALPL, AKR1C3More
NADHhsa00830Retinol metabolism9.80E-041P00325ADH1BMore
NADHhsa00910Nitrogen metabolism5.99E-032P15104, P49448GLUL, GLUD2More
NADHhsa00970Aminoacyl-tRNA biosynthesis7.77E-043O95363, P14868, Q15046FARS2, DARS, KARSMore
NADHhsa00980Metabolism of xenobiotics by cytochrome P4509.14E-054Q16772, P78417, P09211, P11712GSTA3, GSTO1, GSTP1, CYP2C9More
NADHhsa00982Drug metabolism - cytochrome P4501.77E-044P11712, Q16772, P09211, P78417CYP2C9, GSTA3, GSTP1, GSTO1More
NADHhsa00983Drug metabolism - other enzymes1.72E-022Q16772, P09211GSTA3, GSTP1More
NADHhsa01040Biosynthesis of unsaturated fatty acids2.41E-021P51659HSD17B4More
NADHhsa01100Metabolic pathways1.34E-0451Q9Y234, P35790, O14521, Q16772, P09211, Q9UJ14, P15144, P30041, Q99707, O14732, P11310, P27707, Q02153, Q16774, P20839, P00918, P40926, P10768, P55809, P06280, Q7KZN9, Q9Y6K0, P11712, P24666, P15121, P08237, Q02252, P21399, O60701, O14772, P26358, Q9HCC0, P33121, Q9UHK6, P51854, P04406, Q86VZ5, Q9BVK2, P15907, O96024, P36551, P09960, P37837, P50213, Q9UHY7, P43490, Q9BQB6, Q969G6, Q16718, Q13029, Q9NVH6LIPT1, CHKA, SDHD, GSTA3, GSTP1, GGTL3, ANPEP, PRDX6, MTR, IMPA2, ACADM, DCK, GUCY1B3, GUK1, IMPDH1, CA2, MDH2, ESD, OXCT1, GLA, COX15, CEPT1, CYP2C9, ACP1, AKR1B1, PFKM, ALDH6A1, ACO1, UGDH, FPGT, DNMT1, MCCC2, ACSL1, AMACR, TKTL1, GAPDH, SGMS1, ALG8, ST6GAL1, B3GALT4, CPOX, LTA4H, TALDO1, IDH3A, ENOPH1, PBEF1, VKORC1, RFK, NDUFA5, PRDM2, TMLHEMore
NADHhsa01200Carbon metabolism3.96E-0514P04075, P51854, P04406, P08237, P11413, P60174, P37837, P06733, O14521, Q9P2R7, P50213, P21399, P10768, Q02252ALDOA, TKTL1, GAPDH, PFKM, G6PD, TPI1, TALDO1, ENO1, SDHD, SUCLA2, IDH3A, ACO1, ESD, ALDH6A1More
NADHhsa012102-Oxocarboxylic acid metabolism8.17E-042P21399, P50213ACO1, IDH3AMore
NADHhsa01212Fatty acid metabolism3.01E-021P51659HSD17B4More
NADHhsa01230Biosynthesis of amino acids2.08E-0410P60174, P04406, P06733, P04075, P08237, P51854, Q99707, P21399, P50213, P37837TPI1, GAPDH, ENO1, ALDOA, PFKM, TKTL1, MTR, ACO1, IDH3A, TALDO1More
NADHhsa01521EGFR tyrosine kinase inhibitor resistance2.82E-022P42338, Q9NRA1PIK3CB, PDGFCMore
NADHhsa01523Antifolate resistance2.24E-023P41439, P41440, P01375FOLR3, SLC19A1, TNFMore
NADHhsa01524Platinum drug resistance4.58E-034P04637, P48023, Q16772, P09211TP53, FASLG, GSTA3, GSTP1More
NADHhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
NADHhsa03010Ribosome1.79E-0518P62266, P62753, P39019, P25398, P30050, P40429, P62906, P62917, Q9H0U6, Q07020, P61927, P61513, Q02878, P63173, P36578, P05386, P62249, P23396RPS23, RPS6, RPS19, RPS12, RPL12, RPL13A, RPL10A, RPL8, MRPL18, RPL18, RPL37, RPL37A, RPL6, RPL38, RPL4, RPLP1, RPS16, RPS3More
NADHhsa03013RNA transport2.68E-0717P62826, O14980, P52298, O14893, P61326, Q15287, Q7Z3B4, P35658, Q14152, O15371, O75822, P78345, Q14240, Q9Y6A5, Q14232, Q06787, Q53GS7RAN, XPO1, NCBP2, GEMIN2, MAGOH, RNPS1, NUP54, NUP214, EIF3A, EIF3D, EIF3J, RPP38, EIF4A2, TACC3, EIF2B1, FMR1, GLE1More
NADHhsa03015mRNA surveillance pathway4.42E-024O60942, O43148, P52298, Q53GS7RNGTT, RNMT, NCBP2, GLE1More
NADHhsa03020RNA polymerase1.61E-053P30876, P24928, P62487POLR2B, POLR2A, POLR2GMore
NADHhsa03030DNA replication1.48E-023P49005, P33993, P15927POLD2, MCM7, RPA2More
NADHhsa03040Spliceosome1.20E-0512Q14562, O43143, O60508, P08579, P26368, Q07955, Q01130, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, SFRS1, SFRS2, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
NADHhsa03060Protein export2.29E-053Q15070, P37108, Q15005OXA1L, SRP14, SPCS2More
NADHhsa03450Non-homologous end-joining6.80E-052Q9NP87, P13010POLM, XRCC5More
NADHhsa04012ErbB signaling pathway1.34E-024P16333, P19174, P42338, P01106NCK1, PLCG1, PIK3CB, MYCMore
NADHhsa04014Ras signaling pathway4.80E-0511P42338, P20827, Q9NRA1, P49767, Q13009, O43374, P0DP23, P62873, P63218, P50151, P19174PIK3CB, EFNA1, PDGFC, VEGFC, TIAM1, RASA4, CALM1, GNB1, GNG5, GNG10, PLCG1More
NADHhsa04015Rap1 signaling pathway4.83E-038P20827, Q9NRA1, P49767, P11215, Q13009, P42338, P0DP23, P19174EFNA1, PDGFC, VEGFC, ITGAM, TIAM1, PIK3CB, CALM1, PLCG1More
NADHhsa04020Calcium signaling pathway5.78E-0817P27987, Q96DU7, Q08828, P21796, Q13557, P21860, P19174, P61073, P0DP23, P0DP24, P05141, P12236, P51828, P26678, P63092, Q9NRA1, P49767ITPKB, ITPKC, ADCY1, VDAC1, CAMK2D, ERBB3, PLCG1, CXCR4, CALM1, CALM2, SLC25A5, SLC25A6, ADCY7, PLN, GNAS, PDGFC, VEGFCMore
NADHhsa04022cGMP-PKG signaling pathway9.36E-036P61586, P26678, Q99941, P18848, P05141, P12236RHOA, PLN, CREBL1, ATF4, SLC25A5, SLC25A6More
NADHhsa04060Cytokine-cytokine receptor interaction2.42E-0313P27930, P14778, Q06643, Q13651, P25024, P25025, Q9UBD3, P47992, P09341, P19875, P18510, P01730, Q93038IL1R2, IL1R1, LTB, IL10RA, CXCR1, CXCR2, XCL2, XCL1, CXCL1, CXCL2, IL1RN, CD4, TNFRSF25More
NADHhsa04061Viral protein interaction with cytokine and cytokine receptor7.71E-037P09341, P19875, P25024, P25025, P47992, Q9UBD3, Q13651CXCL1, CXCL2, CXCR1, CXCR2, XCL1, XCL2, IL10RAMore
NADHhsa04062Chemokine signaling pathway5.70E-0515P25024, P25025, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q13009, P14598, P42224, P25963, P49841CXCR1, CXCR2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, TIAM1, NCF1, STAT1, NFKBIA, GSK3BMore
NADHhsa04064NF-kappa B signaling pathway1.20E-0513P10415, O00463, P14778, Q04759, Q9UDY8, Q13077, Q16548, P06239, Q13315, P24522, P09341, P19875, Q06643BCL2, TRAF5, IL1R1, PRKCQ, MALT1, TRAF1, BCL2A1, LCK, ATM, GADD45A, CXCL1, CXCL2, LTBMore
NADHhsa04068FoxO signaling pathway6.45E-032P48023, Q96BR1FASLG, SGK3More
NADHhsa04070Phosphatidylinositol signaling system1.12E-025P19174, P0DP23, P42338, P23743, P27987PLCG1, CALM1, PIK3CB, DGKA, ITPKBMore
NADHhsa04071Sphingolipid signaling pathway6.65E-047P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
NADHhsa04072Phospholipase D signaling pathway6.02E-035P42338, P19174, Q14344, P23743, Q9NRA1PIK3CB, PLCG1, GNA13, DGKA, PDGFCMore
NADHhsa04080Neuroactive ligand-receptor interaction1.00E-027P08311, Q15722, P21453, Q9H228, O00398, P21730, P07550CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, ADRB2More
NADHhsa04114Oocyte meiosis3.73E-025Q13557, P0DP24, P51828, P27348, Q13362CAMK2D, CALM2, ADCY7, YWHAQ, PPP2R5CMore
NADHhsa04120Ubiquitin mediated proteolysis3.81E-036Q9UBT2, Q14145, Q13042, P62837, Q15751, Q14669SAE2, KEAP1, CDC16, UBE2D2, HERC1, TRIP12More
NADHhsa04136Autophagy - other3.20E-032O94817, Q9H1Y0ATG12, ATG5More
NADHhsa04140Autophagy - animal5.64E-037Q96RR4, O75460, P22694, Q14643, P10415, Q04759, Q8TEV9CAMKK2, ERN1, PRKACB, ITPR1, BCL2, PRKCQ, SMCR8More
NADHhsa04141Protein processing in endoplasmic reticulum2.05E-026P18848, Q86TM6, P0DMV8, P51668, Q9H3Z4, Q9NR31ATF4, SYVN1, HSPA1A, UBE2D1, DNAJC5, SAR1AMore
NADHhsa04142Lysosome1.46E-027P06865, P38571, Q13510, P07602, P61916, Q04900, Q9Y227HEXA, LIPA, ASAH1, PSAP, NPC2, CD164, ENTPD4More
NADHhsa04144Endocytosis1.38E-0310P0DMV8, Q9H444, O75351, P62491, P42566, Q15438, Q14161, Q96QK1, Q9UMY4, Q9UNH7HSPA1A, CHMP4B, VPS4B, RAB11A, EPS15, PSCD1, GIT2, VPS35, SNX12, SNX6More
NADHhsa04145Phagosome7.63E-0512P63261, Q15080, P14598, Q71U36, Q13509, P68371, P05164, O60603, P35443, P27824, P13765, P30511ACTG1, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, MPO, TLR2, THBS4, CANX, HLA-DOB, HLA-FMore
NADHhsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
NADHhsa04150mTOR signaling pathway2.72E-024P42338, Q9NQL2, Q13322, P49841PIK3CB, RRAGD, GRB10, GSK3BMore
NADHhsa04151PI3K-Akt signaling pathway1.46E-0627P62753, P42338, P21860, P01106, P48023, P04637, P27348, P20827, O14944, Q9NRA1, P49767, P07900, P08238, Q15831, P62873, P63218, P50151, P61952, O15335, P22105, P14784, P01568, Q99941, P18848, Q96BR1, O00141, O95988RPS6, PIK3CB, ERBB3, MYC, FASLG, TP53, YWHAQ, EFNA1, EREG, PDGFC, VEGFC, HSP90AA1, HSP90AB1, STK11, GNB1, GNG5, GNG10, GNG11, CHAD, TNXB, IL2RB, IFNA21, CREBL1, ATF4, SGK3, SGK, TCL1BMore
NADHhsa04152AMPK signaling pathway2.34E-022Q96EB6, P36956SIRT1, SREBF1More
NADHhsa04210Apoptosis3.44E-027Q13315, P10415, O76075, P24522, Q16548, P43234, Q14643ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ITPR1More
NADHhsa04217Necroptosis2.17E-0722P01375, P01568, P23458, P48023, Q13489, Q9NQC7, Q13546, Q14765, P07900, P15104, P05141, P01584, P07384, P0C0S5, Q9BTM1, Q6FI13, Q99878, P10415, Q13557, Q9H444, O43633, O75351TNF, IFNA21, JAK1, FASLG, BIRC3, CYLD, RIPK1, STAT4, HSP90AA1, GLUL, SLC25A5, IL1B, CAPN1, H2AFZ, H2AFJ, H2AC18; H2AC19, H2AC14, BCL2, CAMK2D, CHMP4B, CHMP2A, VPS4BMore
NADHhsa04260Cardiac muscle contraction4.78E-023P67936, P13073, P12074TPM4, COX4I1, COX6A1More
NADHhsa04261Adrenergic signaling in cardiomyocytes3.90E-038P63092, P51828, Q99941, P18848, P26678, Q13362, P0DP24, Q13557GNAS, ADCY7, CREBL1, ATF4, PLN, PPP2R5C, CALM2, CAMK2DMore
NADHhsa04270Vascular smooth muscle contraction2.03E-022P63092, P35579GNAS, MYH9More
NADHhsa04330Notch signaling pathway6.51E-045Q92542, P49768, Q92830, P78504, Q9UM47NCSTN, PSEN1, KAT2A, JAG1, NOTCH3More
NADHhsa04340Hedgehog signaling pathway3.09E-023P22694, Q13635, P10415PRKACB, PTCH1, BCL2More
NADHhsa04360Axon guidance1.43E-037P16333, P20827, O95631, P42338, P23528, P19174, Q06124NCK1, EFNA1, NTN1, PIK3CB, CFL1, PLCG1, PTPN11More
NADHhsa04371Apelin signaling pathway5.99E-059P62873, P63218, P50151, Q13370, Q14814, Q14344, Q13485, Q16566, P0DP23GNB1, GNG5, GNG10, PDE3B, MEF2D, GNA13, SMAD4, CAMK4, CALM1More
NADHhsa04380Osteoclast differentiation2.13E-0411Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P42338, P01584, P14778, O75015, P01375, Q8N149CYLD, GAB2, MAPK14, JAK1, LCK, PIK3CB, IL1B, IL1R1, FCGR3B, TNF, LILRA2More
NADHhsa04390Hippo signaling pathway2.40E-022P35240, Q92796NF2, DLG3More
NADHhsa04510Focal adhesion4.64E-026O75369, Q15942, Q13489, P10415, P49767, P63261FLNB, ZYX, BIRC3, BCL2, VEGFC, ACTG1More
NADHhsa04530Tight junction3.29E-023P16989, P56750, Q14247CSDA, CLDN17, CTTNMore
NADHhsa04540Gap junction7.81E-033P68371, Q71U36, Q9NRA1TUBB2C, TUBA1A, PDGFCMore
NADHhsa04610Complement and coagulation cascades6.02E-053P00734, P0C0L4, P21730F2, C4A, C5AR1More
NADHhsa04612Antigen processing and presentation2.09E-0610P13765, P26715, P26717, Q07444, Q13241, P01732, P30101, P30511, P27824, P08238HLA-DOB, KLRC1, KLRC2, KLRC3, KLRD1, CD8A, PDIA3, HLA-F, CANX, HSP90AB1More
NADHhsa04613Neutrophil extracellular trap formation1.22E-0524P42338, P19174, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, Q93077, P62807, Q93079, O60814, P68431, P21796, P14598, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539PIK3CB, PLCG1, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, H2BC9, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, VDAC1, NCF1, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
NADHhsa04620Toll-like receptor signaling pathway4.00E-024P01568, P42224, P25963, P42338IFNA21, STAT1, NFKBIA, PIK3CBMore
NADHhsa04622RIG-I-like receptor signaling pathway3.49E-024P01568, P25963, Q9H1Y0, Q13546IFNA21, NFKBIA, ATG5, RIPK1More
NADHhsa04623Cytosolic DNA-sensing pathway1.01E-053P01568, Q13546, P25963IFNA21, RIPK1, NFKBIAMore
NADHhsa04625C-type lectin receptor signaling pathway2.21E-038Q9ULY5, P42224, P20749, P25963, P01375, P42338, P0DP23, Q16539CLEC4E, STAT1, BCL3, NFKBIA, TNF, PIK3CB, CALM1, MAPK14More
NADHhsa04640Hematopoietic cell lineage1.66E-0511P13612, P14778, P27930, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P13765ITGA4, IL1R1, IL1R2, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, HLA-DOBMore
NADHhsa04650Natural killer cell mediated cytotoxicity7.25E-0913P01375, P06239, O60880, P20963, P48023, Q13241, P26718, O14931, O75015, P26717, Q07444, Q14953, P26715TNF, LCK, SH2D1A, CD247, FASLG, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KIR2DS5, KLRC1More
NADHhsa04657IL-17 signaling pathway2.40E-037O00463, Q16539, P49841, P14780, Q9UJX4, P80188, P01375TRAF5, MAPK14, GSK3B, MMP9, ANAPC5, LCN2, TNFMore
NADHhsa04658Th1 and Th2 cell differentiation4.53E-1816P25963, Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, P13765, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
NADHhsa04659Th17 cell differentiation1.51E-1216P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9UL17, P23771, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, TBX21, GATA3, HSP90AB1, CD3E, CD3G, CD247More
NADHhsa04660T cell receptor signaling pathway2.17E-1115Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, Q16539, P49841MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, MAPK14, GSK3BMore
NADHhsa04662B cell receptor signaling pathway8.62E-107P25963, P49841, P42338, P60033, P07948, P21854, Q8N149NFKBIA, GSK3B, PIK3CB, CD81, LYN, CD72, LILRA2More
NADHhsa04664Fc epsilon RI signaling pathway4.35E-067P01375, Q16539, P42338, Q9UQC2, P07948, P19174, P09917TNF, MAPK14, PIK3CB, GAB2, LYN, PLCG1, ALOX5More
NADHhsa04666Fc gamma R-mediated phagocytosis2.92E-024P07948, P42338, P19174, P14598LYN, PIK3CB, PLCG1, NCF1More
NADHhsa04668TNF signaling pathway2.21E-025P01375, O00463, Q16539, P20749, P14780TNF, TRAF5, MAPK14, BCL3, MMP9More
NADHhsa04672Intestinal immune network for IgA production2.40E-032P13765, P13612HLA-DOB, ITGA4More
NADHhsa04713Circadian entrainment6.27E-049P0DP23, Q13557, Q02153, P62873, P63218, P50151, P61952, Q08828, P63092CALM1, CAMK2D, GUCY1B3, GNB1, GNG5, GNG10, GNG11, ADCY1, GNASMore
NADHhsa04714Thermogenesis2.92E-027P63092, Q08828, P62753, P13073, P12074, O15239, P05496GNAS, ADCY1, RPS6, COX4I1, COX6A1, NDUFA1, ATP5G1More
NADHhsa04720Long-term potentiation4.55E-022Q16566, O15399CAMK4, GRIN2DMore
NADHhsa04722Neurotrophin signaling pathway2.31E-034P49841, O43524, P48023, P04637GSK3B, FOXO3, FASLG, TP53More
NADHhsa04723Retrograde endocannabinoid signaling7.11E-036P63218, P50151, P48058, Q08828, Q16539, O95298GNG5, GNG10, GRIA4, ADCY1, MAPK14, NDUFC2More
NADHhsa04724Glutamatergic synapse4.57E-0811P48058, O15399, P43003, Q08828, P63092, P62873, P63218, P50151, P61952, P15104, Q9NSB8GRIA4, GRIN2D, SLC1A3, ADCY1, GNAS, GNB1, GNG5, GNG10, GNG11, GLUL, HOMER2More
NADHhsa04725Cholinergic synapse2.98E-034P62873, P63218, P50151, P42338GNB1, GNG5, GNG10, PIK3CBMore
NADHhsa04727GABAergic synapse3.90E-057Q08828, P62873, P63218, P50151, P61952, P15104, Q15111ADCY1, GNB1, GNG5, GNG10, GNG11, GLUL, PLCL1More
NADHhsa04728Dopaminergic synapse8.20E-0412P63092, P63218, P50151, P61952, P49841, Q99941, P18848, Q16539, Q13557, P49407, O15516, P48058GNAS, GNG5, GNG10, GNG11, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, CLOCK, GRIA4More
NADHhsa04730Long-term depression1.10E-052Q14344, P07948GNA13, LYNMore
NADHhsa04744Phototransduction3.15E-042P62873, P0DP23GNB1, CALM1More
NADHhsa04750Inflammatory mediator regulation of TRP channels2.13E-0410P01584, P63092, Q08828, P51828, Q13557, P19174, P42338, P24723, P0DP23, P0DP24IL1B, GNAS, ADCY1, ADCY7, CAMK2D, PLCG1, PIK3CB, PRKCH, CALM1, CALM2More
NADHhsa04810Regulation of actin cytoskeleton2.61E-026P12814, Q13009, P42338, P11215, Q14344, Q9NRA1ACTN1, TIAM1, PIK3CB, ITGAM, GNA13, PDGFCMore
NADHhsa04911Insulin secretion2.54E-066Q08828, P51828, P63092, Q99941, P18848, Q13557ADCY1, ADCY7, GNAS, CREBL1, ATF4, CAMK2DMore
NADHhsa04912GnRH signaling pathway6.67E-0410P17252, Q08828, P51828, P18848, Q13557, Q9Y6R4, Q14643, P0DP24, P63092, P22694PRKCA, ADCY1, ADCY7, ATF4, CAMK2D, MAP3K4, ITPR1, CALM2, GNAS, PRKACBMore
NADHhsa04914Progesterone-mediated oocyte maturation4.00E-024P42338, Q13370, P30304, P08238PIK3CB, PDE3B, CDC25A, HSP90AB1More
NADHhsa04915Estrogen signaling pathway1.54E-025P18848, P51828, P0DMV8, P0DP24, Q15788ATF4, ADCY7, HSPA1A, CALM2, NCOA1More
NADHhsa04916Melanogenesis3.93E-037Q13557, P0DP23, P0DP24, Q9UJU2, P51828, P17252, P04628CAMK2D, CALM1, CALM2, LEF1, ADCY7, PRKCA, WNT1More
NADHhsa04918Thyroid hormone synthesis8.80E-035P63092, Q08828, Q99941, P18848, P02768GNAS, ADCY1, CREBL1, ATF4, ALBMore
NADHhsa04920Adipocytokine signaling pathway2.06E-022Q06124, Q9Y478PTPN11, PRKAB1More
NADHhsa04922Glucagon signaling pathway4.23E-024P22694, P06737, Q12778, Q14643PRKACB, PYGL, FOXO1, ITPR1More
NADHhsa04924Renin secretion1.07E-034P22694, P07550, Q14643, Q13370PRKACB, ADRB2, ITPR1, PDE3BMore
NADHhsa04925Aldosterone synthesis and secretion2.50E-057Q99941, P18848, Q08828, P51828, P0DP24, P63092, Q13557CREBL1, ATF4, ADCY1, ADCY7, CALM2, GNAS, CAMK2DMore
NADHhsa04926Relaxin signaling pathway1.39E-0512P25963, P42338, P62873, P63218, P50151, P61952, Q99941, P18848, P63092, P49767, Q08828, P49407NFKBIA, PIK3CB, GNB1, GNG5, GNG10, GNG11, CREBL1, ATF4, GNAS, VEGFC, ADCY1, ARRB1More
NADHhsa04927Cortisol synthesis and secretion3.93E-044Q99941, P18848, Q08828, P63092CREBL1, ATF4, ADCY1, GNASMore
NADHhsa04928Parathyroid hormone synthesis, secretion and action2.59E-038Q14643, P63092, P22694, P23771, P61586, Q99941, P18848, P10415ITPR1, GNAS, PRKACB, GATA3, RHOA, CREBL1, ATF4, BCL2More
NADHhsa04929GnRH secretion1.13E-032P42338, P49407PIK3CB, ARRB1More
NADHhsa04932Non-alcoholic fatty liver disease2.74E-023P01375, P49841, P48023TNF, GSK3B, FASLGMore
NADHhsa04934Cushing syndrome1.99E-056Q99941, P18848, Q08828, P63092, O15169, Q13557CREBL1, ATF4, ADCY1, GNAS, AXIN1, CAMK2DMore
NADHhsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
NADHhsa04961Endocrine and other factor-regulated calcium reabsorption4.35E-023P20020, P17252, P22694ATP2B1, PRKCA, PRKACBMore
NADHhsa04964Proximal tubule bicarbonate reclamation4.53E-032P00918, P49448CA2, GLUD2More
NADHhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
NADHhsa04971Gastric acid secretion4.68E-023P51828, P0DP24, Q13557ADCY7, CALM2, CAMK2DMore
NADHhsa04972Pancreatic secretion5.06E-035Q14643, P20020, P17252, Q08828, P62491ITPR1, ATP2B1, PRKCA, ADCY1, RAB11AMore
NADHhsa04973Carbohydrate digestion and absorption1.57E-022O43451, P42338MGAM, PIK3CBMore
NADHhsa04974Protein digestion and absorption1.52E-021P02452COL1A1More
NADHhsa04976Bile secretion1.85E-022Q08828, Q14032ADCY1, BAATMore
NADHhsa04979Cholesterol metabolism8.97E-044P35610, P38571, P61916, P21796SOAT1, LIPA, NPC2, VDAC1More
NADHhsa05010Alzheimer disease1.75E-0417Q92542, O15239, O95298, P05496, O15399, Q00535, Q9NZJ5, O75460, P18848, Q71U36, O15169, P05141, P12236, P21796, P28070, P43686, P62195NCSTN, NDUFA1, NDUFC2, ATP5G1, GRIN2D, CDK5, EIF2AK3, ERN1, ATF4, TUBA1A, AXIN1, SLC25A5, SLC25A6, VDAC1, PSMB4, PSMC4, PSMC5More
NADHhsa05012Parkinson disease2.08E-0517O15239, P13073, P12074, P05496, P05141, P12236, P21796, P60604, P63092, P18848, P43686, P62195, P19174, P0DP23, Q13557, Q71U36, Q13509NDUFA1, COX4I1, COX6A1, ATP5G1, SLC25A5, SLC25A6, VDAC1, UBE2G2, GNAS, ATF4, PSMC4, PSMC5, PLCG1, CALM1, CAMK2D, TUBA1A, TUBB3More
NADHhsa05014Amyotrophic lateral sclerosis4.65E-0519O15399, P20333, O15239, O95298, P05496, Q9NZJ5, O75460, P18848, O60282, Q71U36, P28070, P43686, P62195, Q8TEV9, P21796, P51991, Q99567, P35658, P43243GRIN2D, TNFRSF1B, NDUFA1, NDUFC2, ATP5G1, EIF2AK3, ERN1, ATF4, KIF5C, TUBA1A, PSMB4, PSMC4, PSMC5, SMCR8, VDAC1, HNRPA3, NUP88, NUP214, MATR3More
NADHhsa05016Huntington disease2.46E-029O95298, P13073, P12074, P24928, P30876, P62487, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, ERN1, PSMB4, PSMD12More
NADHhsa05020Prion disease4.70E-0617P01584, P46531, O15239, P05496, P13073, P12074, O15399, Q9NZJ5, P18848, P05141, P12236, P21796, P43686, P62195, Q71U36, P51636, Q99941IL1B, NOTCH1, NDUFA1, ATP5G1, COX4I1, COX6A1, GRIN2D, EIF2AK3, ATF4, SLC25A5, SLC25A6, VDAC1, PSMC4, PSMC5, TUBA1A, CAV2, CREBL1More
NADHhsa05022Pathways of neurodegeneration - multiple diseases1.73E-0423O15399, Q13509, P68371, P10415, O15239, O95298, P05496, Q8TEV9, O75460, P18848, Q13561, P05141, P12236, P20333, P07384, Q00535, O15169, P04628, P0DP23, Q13557, P28070, P43686, P62195GRIN2D, TUBB3, TUBB2C, BCL2, NDUFA1, NDUFC2, ATP5G1, SMCR8, ERN1, ATF4, DCTN2, SLC25A5, SLC25A6, TNFRSF1B, CAPN1, CDK5, AXIN1, WNT1, CALM1, CAMK2D, PSMB4, PSMC4, PSMC5More
NADHhsa05030Cocaine addiction2.40E-023P63092, Q99941, P18848GNAS, CREBL1, ATF4More
NADHhsa05031Amphetamine addiction1.97E-055P0DP24, Q13557, P63092, Q99941, P18848CALM2, CAMK2D, GNAS, CREBL1, ATF4More
NADHhsa05032Morphine addiction7.60E-035P62873, P63218, P50151, Q13370, P43250GNB1, GNG5, GNG10, PDE3B, GRK6More
NADHhsa05034Alcoholism1.49E-0720P63092, Q99941, P18848, Q13547, P0DP23, P0DP24, Q96RR4, P62873, P62879, P63218, P50151, P61952, P0C0S5, Q9BTM1, Q93077, P62807, Q93079, O60814, P84243, P68431GNAS, CREBL1, ATF4, HDAC1, CALM1, CALM2, CAMKK2, GNB1, GNB2, GNG5, GNG10, GNG11, H2AFZ, H2AFJ, HIST1H2AC, HIST1H2BC, H2BC9, H2BC12, H3F3A, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
NADHhsa05120Epithelial cell signaling in Helicobacter pylori infection2.64E-036Q16539, P09341, P19875, P25024, P25025, P07948MAPK14, CXCL1, CXCL2, CXCR1, CXCR2, LYNMore
NADHhsa05132Salmonella infection1.97E-0720P25963, P08238, Q9UJU2, P01106, P63261, P42338, Q15669, Q13546, Q13489, P10415, P04406, O75369, O60603, Q9BQS8, P51808, Q13561, Q71U36, Q13509, P68371, P49754NFKBIA, HSP90AB1, LEF1, MYC, ACTG1, PIK3CB, RHOH, RIPK1, BIRC3, BCL2, GAPDH, FLNB, TLR2, FYCO1, DYNLT3, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41More
NADHhsa05133Pertussis2.70E-032P10145, P0C0L4IL8, C4AMore
NADHhsa05134Legionellosis1.17E-033P01584, Q9NR31, P0DMV8IL1B, SAR1A, HSPA1AMore
NADHhsa05135Yersinia infection9.51E-036P13612, P06239, Q16539, P42338, P49841, P01730ITGA4, LCK, MAPK14, PIK3CB, GSK3B, CD4More
NADHhsa05140Leishmaniasis3.76E-026O75015, P14598, O60603, P01375, P29350, Q15080FCGR3B, NCF1, TLR2, TNF, PTPN6, NCF4More
NADHhsa05143African trypanosomiasis7.50E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
NADHhsa05144Malaria2.79E-044P69905, P68871, O60603, P10145HBA2, HBB, TLR2, IL8More
NADHhsa05146Amoebiasis4.52E-057P09341, P19875, P14778, P27930, P05089, P12814, P08311CXCL1, CXCL2, IL1R1, IL1R2, ARG1, ACTN1, CTSGMore
NADHhsa05150Staphylococcus aureus infection4.66E-024P0C0L4, P21730, P21462, P13646C4A, C5AR1, FPR1, KRT13More
NADHhsa05152Tuberculosis1.14E-028Q13488, Q15075, P0DP23, P48382, O60603, P10415, P01568, Q9UDY8TCIRG1, EEA1, CALM1, RFX5, TLR2, BCL2, IFNA21, MALT1More
NADHhsa05160Hepatitis C1.33E-035P60033, P49841, P04637, P01375, P48023CD81, GSK3B, TP53, TNF, FASLGMore
NADHhsa05162Measles2.33E-0412P01568, P25963, P23458, P42224, P14784, P07766, P42338, P0DMV8, P11142, P01584, Q9NP90, P30281IFNA21, NFKBIA, JAK1, STAT1, IL2RB, CD3E, PIK3CB, HSPA1A, HSPA8, IL1B, RAB9B, CCND3More
NADHhsa05163Human cytomegalovirus infection1.12E-0925P42338, P01375, P30511, P25963, P62873, P63218, P50151, P0DP23, P0DP24, Q14344, P51828, P23458, P49841, P01106, P14778, P01584, P61073, Q13651, P25025, Q16539, P18848, O00463, P30101, P61769, P01568PIK3CB, TNF, HLA-F, NFKBIA, GNB1, GNG5, GNG10, CALM1, CALM2, GNA13, ADCY7, JAK1, GSK3B, MYC, IL1R1, IL1B, CXCR4, IL10RA, CXCR2, MAPK14, ATF4, TRAF5, PDIA3, B2M, IFNA21More
NADHhsa05164Influenza A2.95E-038P01584, P23458, P05141, Q9UBU9, Q9GZY0, P48023, P62491, P30281IL1B, JAK1, SLC25A5, NXF1, NXF2; NXF2B, FASLG, RAB11A, CCND3More
NADHhsa05167Kaposi sarcoma-associated herpesvirus infection7.49E-0511P01568, P42224, P25963, P42338, P62873, P63218, P50151, P19174, P07948, P01106, P0DP23IFNA21, STAT1, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, PLCG1, LYN, MYC, CALM1More
NADHhsa05168Herpes simplex virus 1 infection1.84E-0525Q9UKJ0, Q06124, O60603, P25963, P01568, P04637, Q9GZY0, P42224, Q07955, Q01130, Q13243, P48023, Q13489, P30101, P42338, Q13398, P51522, Q9NR11, Q9HCX3, P17097, Q03923, O75820, P98182, Q9UDV6, P10415PILRB, PTPN11, TLR2, NFKBIA, IFNA21, TP53, NXF2; NXF2B, STAT1, SFRS1, SFRS2, SFRS5, FASLG, BIRC3, PDIA3, PIK3CB, ZNF211, ZNF83, ZNF302, ZNF304, ZNF7, ZNF85, ZNF189, ZNF200, ZNF212, BCL2More
NADHhsa05169Epstein-Barr virus infection2.49E-0719P20023, P13765, P01106, Q13547, Q92769, O00463, P25963, Q16539, P42338, P07948, P30101, Q13761, P24522, O75293, P42224, P01568, P07766, P09693, P20963CR2, HLA-DOB, MYC, HDAC1, HDAC2, TRAF5, NFKBIA, MAPK14, PIK3CB, LYN, PDIA3, RUNX3, GADD45A, GADD45B, STAT1, IFNA21, CD3E, CD3G, CD247More
NADHhsa05170Human immunodeficiency virus 1 infection4.04E-0520P42338, P62873, P63218, P50151, P0DP23, P17252, Q13546, O00463, P30101, P01568, P01730, P25963, O60603, P19174, P07766, P09693, P20963, P10415, Q13619, Q9Y6Q5PIK3CB, GNB1, GNG5, GNG10, CALM1, PRKCA, RIPK1, TRAF5, PDIA3, IFNA21, CD4, NFKBIA, TLR2, PLCG1, CD3E, CD3G, CD247, BCL2, CUL4A, AP1M2More
NADHhsa05171Coronavirus disease - COVID-194.83E-0313P01584, P23396, P62753, P25398, P39019, P62266, P62906, P36578, Q02878, P61927, P61513, P63173, P05386IL1B, RPS3, RPS6, RPS12, RPS19, RPS23, RPL10A, RPL4, RPL6, RPL37, RPL37A, RPL38, RPLP1More
NADHhsa05200Pathways in cancer2.01E-0420P17301, P42338, P08238, P42224, P25963, P19174, P01106, P43246, P20585, Q13547, P49767, P62873, P62879, P63218, P50151, Q14344, O75293, P0DP23, P01568, P14784ITGA2, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, MSH2, MSH3, HDAC1, VEGFC, GNB1, GNB2, GNG5, GNG10, GNA13, GADD45B, CALM1, IFNA21, IL2RBMore
NADHhsa05202Transcriptional misregulation in cancer1.24E-0420Q12778, Q15532, Q13315, P41732, P14780, P27930, P14923, Q15744, Q16548, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, P12980, P24522FOXO1, SS18, ATM, TSPAN7, MMP9, IL1R2, JUP, CEBPE, BCL2A1, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, LYL1, GADD45AMore
NADHhsa05203Viral carcinogenesis2.57E-0618Q12933, Q99941, P18848, P42229, P42338, P06746, P07948, P27348, P29083, Q13547, Q15283, P61586, P12814, P25963, P61978, P62807, Q93079, O60814TRAF2, CREBL1, ATF4, STAT5A, PIK3CB, POLB, LYN, YWHAQ, GTF2E1, HDAC1, RASA2, RHOA, ACTN1, NFKBIA, HNRPK, HIST1H2BC, H2BC9, H2BC12More
NADHhsa05204Chemical carcinogenesis1.77E-044Q16772, P09211, P78417, P11712GSTA3, GSTP1, GSTO1, CYP2C9More
NADHhsa05205Proteoglycans in cancer7.96E-039Q13557, P63261, P17844, O60603, P21860, P62753, Q06124, P08962, P51636CAMK2D, ACTG1, DDX5, TLR2, ERBB3, RPS6, PTPN11, CD63, CAV2More
NADHhsa05206MicroRNAs in cancer8.00E-0517P30304, P46527, P09493, P21860, P01106, P42338, P61978, P46531, P35226, Q13547, Q92769, P63279, P22105, P61586, P20827, O15151, P19174CDC25A, CDKN1B, TPM1, ERBB3, MYC, PIK3CB, HNRPK, NOTCH1, BMI1, HDAC1, HDAC2, UBE2I, TNXB, RHOA, EFNA1, MDM4, PLCG1More
NADHhsa05214Glioma1.34E-024P0DP23, P42338, P19174, O75293CALM1, PIK3CB, PLCG1, GADD45BMore
NADHhsa05217Basal cell carcinoma2.83E-023Q13635, Q9UJU2, P24522PTCH1, LEF1, GADD45AMore
NADHhsa05218Melanoma9.99E-043Q9NRA1, P42338, O75293PDGFC, PIK3CB, GADD45BMore
NADHhsa05219Bladder cancer4.51E-021P04637TP53More
NADHhsa05220Chronic myeloid leukemia2.17E-025Q13547, P01106, P25963, P42338, O75293HDAC1, MYC, NFKBIA, PIK3CB, GADD45BMore
NADHhsa05222Small cell lung cancer2.41E-026P10826, Q13489, P10415, P25963, Q13077, O75293RARB, BIRC3, BCL2, NFKBIA, TRAF1, GADD45BMore
NADHhsa05230Central carbon metabolism in cancer1.12E-021P11413G6PDMore
NADHhsa05231Choline metabolism in cancer3.24E-045P42338, Q9NRA1, Q9Y259, P19174, P23743PIK3CB, PDGFC, CHKB, PLCG1, DGKAMore
NADHhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.50E-0914P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P42224, O60603, P10747, Q04759, Q16539, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, STAT1, TLR2, CD28, PRKCQ, MAPK14, CD4More
NADHhsa05321Inflammatory bowel disease1.44E-045O60603, P13765, Q14765, Q9UL17, P23771TLR2, HLA-DOB, STAT4, TBX21, GATA3More
NADHhsa05322Systemic lupus erythematosus1.49E-058P08311, P09871, Q93077, P62807, Q16778, O60814, P68431, P12814CTSG, C1S, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1More
NADHhsa05323Rheumatoid arthritis1.60E-024P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
NADHhsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
NADHhsa05332Graft-versus-host disease1.74E-066P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
NADHhsa05340Primary immunodeficiency3.47E-034P01730, P01732, P07766, P06239CD4, CD8A, CD3E, LCKMore
NADHhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
NADHhsa05415Diabetic cardiomyopathy1.65E-0518P17252, P05141, P12236, P14598, Q15080, O15239, Q16718, O14521, P05496, P13073, P12074, P49841, Q13557, P14780, P37173, P04406, P11413, P26678PRKCA, SLC25A5, SLC25A6, NCF1, NCF4, NDUFA1, NDUFA5, SDHD, ATP5G1, COX4I1, COX6A1, GSK3B, CAMK2D, MMP9, TGFBR2, GAPDH, G6PD, PLNMore
NADHhsa05418Fluid shear stress and atherosclerosis1.08E-037Q16539, Q14145, P10599, P14780, P01375, P14778, P27930MAPK14, KEAP1, TXN, MMP9, TNF, IL1R1, IL1R2More

Community members of Nadh (SDC: 4.95)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
O60701UGDHUDPNoneglucose 6NonedehydrogenaseReported00.05890.00670.21610.2589
P00325ADH1BAllNonetransNoneretinol dehydrogenase [NAD(+)] ADH1BReported00.75050.04520.1530.6186
P11766ADH5Alcohol dehydrogenase classNone3Reported00.2650.13970.21460.6265
P15121AKR1B1AldoNoneketo reductase family 1 member B1Reported10.56830.6290.2141.7562
P40926MDH2Malate dehydrogenase, mitochondrialReported00.47210.16110.24740.8055
P51659HSD17B4Peroxisomal multifunctional enzyme type 2Reported00.40770.00670.23920.4564
P07195LDHBLNonelactate dehydrogenase B chainReported00.01670.17490.2310.5892
P40925MDH1Malate dehydrogenase, cytoplasmicReported00.35660.27460.24260.97
P50213IDH3AIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialReported00.12210.01530.28370.3755
P42330AKR1C3AldoNoneketo reductase family 1 member C3Reported00.40170.83480.17482.0453
P20839IMPDH1InosineNone5'Nonemonophosphate dehydrogenase 1Reported00.19280.13070.16530.5231
Q02252ALDH6A1MethylmalonateNonesemialdehyde dehydrogenase [acylating], mitochondrialReported00.43340.01480.24280.4891
P00352ALDH1A1Aldehyde dehydrogenase 1A1Reported00.32080.29250.15430.8998
P04406GAPDHGlyceraldehydeNone3Nonephosphate dehydrogenaseReported00.45350.12230.46660.938
P51648ALDH3A2Aldehyde dehydrogenase family 3 member A2Reported00.08670.00670.19580.2525
P51649ALDH5A1SuccinateNonesemialdehyde dehydrogenase, mitochondrialReported00.1730.07780.1520.394
P30043BLVRBFlavin reductaseReported00.08430.020.17080.253
P53004BLVRABiliverdin reductase AReported00.07940.00670.15880.2118
P00374DHFRDihydrofolate reductaseReported00.3380.18680.22630.7688
P49448GLUD2Glutamate dehydrogenase 2, mitochondrialReported00.16410.01970.32420.4456
P16083NQO2Ribosyldihydronicotinamide dehydrogenase [quinone]Reported00.29580.313400.7747
P00387CYB5R3NADHNonecytochrome b5 reductase 3Reported00.21240.01330.11230.2452
Q13423NNTNAD(P) transhydrogenase, mitochondrialReported00.14520.01330.15390.2531
Q16718NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5Reported00.06660.00670.52910.5757
O95182NDUFA7NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7Reported00.49320.00670.52910.789
O15239NDUFA1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1Reported00.47760.00670.52910.7812
O95298NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2Reported00.28560.01330.52910.6986
P19404NDUFV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialReported00.39370.00670.52910.7393
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
P22748CA4Carbonic anhydrase 4Predicted00.00560.82670.16091.8171
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
Q9HB89NMUR1NeuromedinNoneU receptor 1Predicted00.00240.30300.6072
P28332ADH6Alcohol dehydrogenase 6Predicted00.0580.01250.1530.207
Q08477CYP4F3Cytochrome P450 4F3Predicted10.25770.00320.15650.2916
Q9HCS2CYP4F12Cytochrome P450 4F12Predicted00.12710.003100.0697
Q9UHQ9CYB5R1NADHNonecytochrome b5 reductase 1Predicted00.46430.01090.11230.3663
P14550AKR1A1AldoNoneketo reductase family 1 member A1Predicted10.30560.06210.17370.4508
Q9BPW9DHRS9Dehydrogenase/reductase SDR family member 9Predicted00.04540.04530.15430.2677
P11310ACADMMediumNonechain specific acylNoneCoA dehydrogenase, mitochondrialPredicted10.02140.01170.18020.2142
P26440IVDIsovalerylNoneCoA dehydrogenase, mitochondrialPredicted10.05930.01140.17750.23
P11413G6PDGlucoseNone6Nonephosphate 1NonedehydrogenasePredicted10.44350.63690.29291.7884
P33260CYP2C18Cytochrome P450 2C18Predicted10.02390.07560.15280.316
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P21953BCKDHB2Noneoxoisovalerate dehydrogenase subunit beta, mitochondrialPredicted00.1820.00230.17420.2698
Q8NBQ5HSD17B11Estradiol 17NonebetaNonedehydrogenase 11Predicted00.31330.004500.1657
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)