PharmaCoNets of Morphine (SPCN: 22.96 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Apomorphinehsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Apomorphinehsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Apomorphinehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Apomorphinehsa00500Starch and sucrose metabolism1.47E-023O43451, P46976, P06737MGAM, GYG1, PYGLMore
Apomorphinehsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Apomorphinehsa00730Thiamine metabolism4.07E-022P05186, P24666ALPL, ACP1More
Apomorphinehsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Apomorphinehsa00983Drug metabolism - other enzymes3.50E-023P04183, P32320, P05164TK1, CDA, MPOMore
Apomorphinehsa01100Metabolic pathways4.43E-0223Q9NR34, P05089, P32320, P22748, P55809, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, P57054, Q9UNP4, Q9BX95, P32321, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737MAN1C1, ARG1, CDA, CA4, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, PIGP, ST3GAL5, SGPP1, DCTD, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGLMore
Apomorphinehsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Apomorphinehsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Apomorphinehsa01523Antifolate resistance3.80E-022Q92820, P04818GGH, TYMSMore
Apomorphinehsa02010ABC transporters2.17E-033P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Apomorphinehsa03010Ribosome1.03E-022P46777, P50914RPL5, RPL14More
Apomorphinehsa03013RNA transport3.98E-029P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q9Y6A5NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, TACC3More
Apomorphinehsa03020RNA polymerase1.81E-021P24928POLR2AMore
Apomorphinehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Apomorphinehsa04012ErbB signaling pathway3.31E-021Q13153PAK1More
Apomorphinehsa04024cAMP signaling pathway4.80E-021Q13153PAK1More
Apomorphinehsa04064NF-kappa B signaling pathway7.08E-0514P10415, Q13489, O00463, Q13546, P14778, Q04759, Q9UDY8, Q13077, Q16548, Q8WV28, Q13315, P24522, P09341, Q9UNE0BCL2, BIRC3, TRAF5, RIPK1, IL1R1, PRKCQ, MALT1, TRAF1, BCL2A1, BLNK, ATM, GADD45A, CXCL1, EDARMore
Apomorphinehsa04071Sphingolipid signaling pathway7.35E-057P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2More
Apomorphinehsa04080Neuroactive ligand-receptor interaction2.16E-039P08311, P28472, Q15722, P21453, Q9H228, O00398, P21730, Q16581, P07550CTSG, GABRB3, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, C3AR1, ADRB2More
Apomorphinehsa04110Cell cycle6.80E-036P06493, O75293, P30304, P33981, P42773, P01106CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYCMore
Apomorphinehsa04114Oocyte meiosis1.33E-024P51812, Q02750, P16298, Q17RY0RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Apomorphinehsa04115p53 signaling pathway3.98E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Apomorphinehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Apomorphinehsa04142Lysosome3.31E-023P43234, Q9UBR2, P34059CTSO, CTSZ, GALNSMore
Apomorphinehsa04146Peroxisome2.42E-025O43933, P56589, Q9UKG9, O75521, P33121PEX1, PEX3, CROT, ECI2, ACSL1More
Apomorphinehsa04150mTOR signaling pathway3.60E-023Q02750, Q9NQL2, P51812MAP2K1, RRAGD, RPS6KA3More
Apomorphinehsa04210Apoptosis3.77E-028Q13315, P10415, O76075, P24522, Q16548, P43234, P18848, Q14643ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ATF4, ITPR1More
Apomorphinehsa04211Longevity regulating pathway1.18E-023Q12778, Q9UEF7, Q96KQ7FOXO1, KL, EHMT2More
Apomorphinehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Apomorphinehsa04217Necroptosis1.85E-037P01375, P01568, P48023, Q13489, Q13546, Q14765, Q99878TNF, IFNA21, FASLG, BIRC3, RIPK1, STAT4, H2AC14More
Apomorphinehsa04218Cellular senescence4.79E-024P01106, O75293, P30304, P06493MYC, GADD45B, CDC25A, CDK1More
Apomorphinehsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Apomorphinehsa04370VEGF signaling pathway2.68E-033P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Apomorphinehsa04392Hippo signaling pathway - multiple species1.51E-021Q13153PAK1More
Apomorphinehsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Apomorphinehsa04612Antigen processing and presentation2.09E-048P13765, P48382, Q14953, P26715, P26717, Q13241, P01732, P01375HLA-DOB, RFX5, KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Apomorphinehsa04613Neutrophil extracellular trap formation3.12E-0521P11215, O60603, P05164, P08246, Q9UM07, Q13547, P04908, Q6FI13, Q93077, P58876, Q16778, O60814, P68431, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, H2BC5, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Apomorphinehsa04620Toll-like receptor signaling pathway4.16E-022Q13546, P01568RIPK1, IFNA21More
Apomorphinehsa04621NOD-like receptor signaling pathway4.72E-023P01568, Q13489, Q13546IFNA21, BIRC3, RIPK1More
Apomorphinehsa04622RIG-I-like receptor signaling pathway2.39E-022P01568, Q13546IFNA21, RIPK1More
Apomorphinehsa04623Cytosolic DNA-sensing pathway2.20E-032P01568, Q13546IFNA21, RIPK1More
Apomorphinehsa04625C-type lectin receptor signaling pathway3.31E-021Q13153PAK1More
Apomorphinehsa04630JAK-STAT signaling pathway1.44E-024P01106, Q09472, P48551, P16871MYC, EP300, IFNAR2, IL7RMore
Apomorphinehsa04640Hematopoietic cell lineage1.75E-038P21926, P20023, P11836, P07766, P09693, P01730, P09564, P16871CD9, CR2, MS4A1, CD3E, CD3G, CD4, CD7, IL7RMore
Apomorphinehsa04650Natural killer cell mediated cytotoxicity4.51E-0611P16298, P50591, P01375, P20963, Q02750, Q13153, Q13241, P26718, P26717, Q14953, P26715PPP3CB, TNFSF10, TNF, CD247, MAP2K1, PAK1, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Apomorphinehsa04657IL-17 signaling pathway5.71E-049O00463, Q16539, P49841, P09341, P19875, P14780, Q9UJX4, P80188, P01375TRAF5, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, ANAPC5, LCN2, TNFMore
Apomorphinehsa04660T cell receptor signaling pathway3.61E-021Q13153PAK1More
Apomorphinehsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Apomorphinehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Apomorphinehsa04720Long-term potentiation1.38E-023P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Apomorphinehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Apomorphinehsa04725Cholinergic synapse4.83E-024P22694, Q14643, P18848, P10415PRKACB, ITPR1, ATF4, BCL2More
Apomorphinehsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Apomorphinehsa04742Taste transduction1.01E-021P30939HTR1FMore
Apomorphinehsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Apomorphinehsa04914Progesterone-mediated oocyte maturation2.94E-023Q17RY0, P51812, Q02750CPEB4, RPS6KA3, MAP2K1More
Apomorphinehsa04915Estrogen signaling pathway2.96E-025P14780, P22694, P18848, Q14643, P10415MMP9, PRKACB, ATF4, ITPR1, BCL2More
Apomorphinehsa04918Thyroid hormone synthesis3.50E-023P22694, P18848, Q14643PRKACB, ATF4, ITPR1More
Apomorphinehsa04919Thyroid hormone signaling pathway4.44E-023P60709, Q09472, P01106ACTB, EP300, MYCMore
Apomorphinehsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Apomorphinehsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Apomorphinehsa04927Cortisol synthesis and secretion4.44E-043Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
Apomorphinehsa04928Parathyroid hormone synthesis, secretion and action2.13E-025Q14643, P22694, P23771, P18848, P10415ITPR1, PRKACB, GATA3, ATF4, BCL2More
Apomorphinehsa04932Non-alcoholic fatty liver disease2.44E-035P01375, P49841, P48023, Q16718, O14521TNF, GSK3B, FASLG, NDUFA5, SDHDMore
Apomorphinehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Apomorphinehsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Apomorphinehsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Apomorphinehsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Apomorphinehsa04975Fat digestion and absorption2.80E-021O14494PLPP1More
Apomorphinehsa04976Bile secretion3.32E-022O43315, P08183AQP9, ABCB1More
Apomorphinehsa05020Prion disease3.80E-024Q16718, O14521, P49841, Q16539NDUFA5, SDHD, GSK3B, MAPK14More
Apomorphinehsa05022Pathways of neurodegeneration - multiple diseases1.24E-026P49841, Q16718, O14521, Q13561, Q16539, Q08752GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPIDMore
Apomorphinehsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Apomorphinehsa05034Alcoholism2.10E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Apomorphinehsa05120Epithelial cell signaling in Helicobacter pylori infection3.10E-035Q16539, Q13153, P09341, P25024, P25025MAPK14, PAK1, CXCL1, CXCR1, CXCR2More
Apomorphinehsa05132Salmonella infection9.85E-034Q13546, Q13489, O60282, P68371RIPK1, BIRC3, KIF5C, TUBB2CMore
Apomorphinehsa05133Pertussis4.20E-021P0C0L4C4AMore
Apomorphinehsa05140Leishmaniasis2.69E-025O75015, P13765, O60603, P49006, Q16539FCGR3B, HLA-DOB, TLR2, MARCKSL1, MAPK14More
Apomorphinehsa05143African trypanosomiasis7.50E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Apomorphinehsa05144Malaria1.44E-035P69905, P68871, P01375, P35443, P26718HBA2, HBB, TNF, THBS4, KLRK1More
Apomorphinehsa05146Amoebiasis3.33E-039P09341, P19875, P14778, P27930, P01375, O60603, P05089, P30679, P22694CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, ARG1, GNA15, PRKACBMore
Apomorphinehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Apomorphinehsa05163Human cytomegalovirus infection3.64E-027Q14643, P49841, P14778, P25025, Q16539, P04637, O00463ITPR1, GSK3B, IL1R1, CXCR2, MAPK14, TP53, TRAF5More
Apomorphinehsa05164Influenza A8.62E-034Q09472, P48551, P29728, P60709EP300, IFNAR2, OAS2, ACTBMore
Apomorphinehsa05167Kaposi sarcoma-associated herpesvirus infection1.94E-024P62879, P16298, Q02750, P0CG47GNB2, PPP3CB, MAP2K1, UBBMore
Apomorphinehsa05169Epstein-Barr virus infection1.42E-025P20023, P01106, P48551, P29728, P09693CR2, MYC, IFNAR2, OAS2, CD3GMore
Apomorphinehsa05170Human immunodeficiency virus 1 infection6.02E-035Q02750, P62879, P16298, Q05397, P20333MAP2K1, GNB2, PPP3CB, PTK2, TNFRSF1BMore
Apomorphinehsa05171Coronavirus disease - COVID-191.93E-024P48551, P29728, P46777, P50914IFNAR2, OAS2, RPL5, RPL14More
Apomorphinehsa05202Transcriptional misregulation in cancer1.08E-0419Q15532, Q13315, P41732, P14780, P27930, P14923, Q15744, Q16548, P11215, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, Q13547, P12980, P24522SS18, ATM, TSPAN7, MMP9, IL1R2, JUP, CEBPE, BCL2A1, ITGAM, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, HDAC1, LYL1, GADD45AMore
Apomorphinehsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Apomorphinehsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Apomorphinehsa05211Renal cell carcinoma3.42E-033Q09472, Q99814, Q13153EP300, EPAS1, PAK1More
Apomorphinehsa05213Endometrial cancer3.79E-022O15169, Q02750AXIN1, MAP2K1More
Apomorphinehsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
Apomorphinehsa05219Bladder cancer4.07E-022P14780, P04637MMP9, TP53More
Apomorphinehsa05223Non-small cell lung cancer1.39E-023P10826, Q9HC35, O75293RARB, EML4, GADD45BMore
Apomorphinehsa05224Breast cancer4.75E-024P49841, Q92837, P04637, P24522GSK3B, FRAT1, TP53, GADD45AMore
Apomorphinehsa05226Gastric cancer3.79E-022Q02750, O15169MAP2K1, AXIN1More
Apomorphinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.94E-038O95267, P07766, P09693, P06239, O60603, Q16539, Q9HC35, P01730RASGRP1, CD3E, CD3G, LCK, TLR2, MAPK14, EML4, CD4More
Apomorphinehsa05321Inflammatory bowel disease1.19E-036P01375, P13765, Q14765, Q9UL17, P23771, Q9HBE5TNF, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Apomorphinehsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Apomorphinehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Apomorphinehsa05332Graft-versus-host disease1.91E-056P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Apomorphinehsa05340Primary immunodeficiency1.28E-034P01730, P11912, P07766, P06239CD4, CD79A, CD3E, LCKMore
Apomorphinehsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Apomorphinehsa05415Diabetic cardiomyopathy1.28E-024Q16718, O14521, Q16539, P49841NDUFA5, SDHD, MAPK14, GSK3BMore
Apomorphinehsa05418Fluid shear stress and atherosclerosis2.62E-026Q16539, P10599, P14780, P04637, P14778, P27930MAPK14, TXN, MMP9, TP53, IL1R1, IL1R2More
Diamorphinehsa00071Fatty acid degradation4.66E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Diamorphinehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Diamorphinehsa00500Starch and sucrose metabolism9.22E-043O43451, P46976, P06737MGAM, GYG1, PYGLMore
Diamorphinehsa00730Thiamine metabolism4.66E-022P05186, P24666ALPL, ACP1More
Diamorphinehsa00770Pantothenate and CoA biosynthesis7.90E-033O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Diamorphinehsa00830Retinol metabolism3.49E-021P00325ADH1BMore
Diamorphinehsa00970Aminoacyl-tRNA biosynthesis1.58E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Diamorphinehsa01524Platinum drug resistance1.13E-025P10415, Q13489, P78417, P23025, P43246BCL2, BIRC3, GSTO1, XPA, MSH2More
Diamorphinehsa02010ABC transporters2.29E-022P45844, P08183ABCG1, ABCB1More
Diamorphinehsa03008Ribosome biogenesis in eukaryotes2.60E-035Q9NYH9, P78345, Q9BVP2, O15381, Q9GZY0UTP6, RPP38, GNL3, NVL, NXF2; NXF2BMore
Diamorphinehsa03013RNA transport2.29E-0413O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, Q9Y6A5, P51114XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, TACC3, FXR1More
Diamorphinehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Diamorphinehsa03040Spliceosome5.79E-037Q14562, O43143, O60508, Q99633, Q13595, Q01130, Q9UMS4DHX8, DHX15, CDC40, PRPF18, TRA2A, SFRS2, PRPF19More
Diamorphinehsa04014Ras signaling pathway4.65E-023Q15311, P0DP23, P17612RALBP1, CALM1, PRKACAMore
Diamorphinehsa04015Rap1 signaling pathway1.58E-026P20827, P49767, P63261, P25116, P0DP23, P17252EFNA1, VEGFC, ACTG1, F2R, CALM1, PRKCAMore
Diamorphinehsa04020Calcium signaling pathway1.16E-037Q16566, P17252, O15399, P25116, P0DP23, P23634, P49767CAMK4, PRKCA, GRIN2D, F2R, CALM1, ATP2B4, VEGFCMore
Diamorphinehsa04024cAMP signaling pathway2.84E-025P0DP23, P23634, Q16566, O15399, P25116CALM1, ATP2B4, CAMK4, GRIN2D, F2RMore
Diamorphinehsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, P25025, P14784CXCL1, CXCL2, CXCR1, CXCR2, IL2RBMore
Diamorphinehsa04062Chemokine signaling pathway2.43E-0414P25024, P25025, P09341, P19875, P47992, Q9UBD3, P07948, P42338, P19174, P63218, P50151, P49407, Q08881, P49841CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNG5, GNG10, ARRB1, ITK, GSK3BMore
Diamorphinehsa04064NF-kappa B signaling pathway3.08E-0313P10415, P51617, Q13546, P14778, P19174, Q04759, Q9UDY8, Q13077, P06239, P24522, P09341, P19875, Q06643BCL2, IRAK1, RIPK1, IL1R1, PLCG1, PRKCQ, MALT1, TRAF1, LCK, GADD45A, CXCL1, CXCL2, LTBMore
Diamorphinehsa04070Phosphatidylinositol signaling system4.07E-024P0DP23, Q14643, O14732, P17252CALM1, ITPR1, IMPA2, PRKCAMore
Diamorphinehsa04071Sphingolipid signaling pathway1.90E-038P17252, Q9H228, P01375, Q13362, Q16537, Q9BX95, P04637, P10415PRKCA, EDG8, TNF, PPP2R5C, PPP2R5E, SGPP1, TP53, BCL2More
Diamorphinehsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Diamorphinehsa04114Oocyte meiosis2.15E-023P0DP23, P17612, Q13362CALM1, PRKACA, PPP2R5CMore
Diamorphinehsa04144Endocytosis4.07E-035Q9H444, O75351, P42566, Q15438, Q14161CHMP4B, VPS4B, EPS15, PSCD1, GIT2More
Diamorphinehsa04145Phagosome1.86E-025P63261, Q15080, Q13509, P68371, P27824ACTG1, NCF4, TUBB3, TUBB2C, CANXMore
Diamorphinehsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Diamorphinehsa04217Necroptosis4.56E-034P23458, Q9NQC7, Q9H444, O75351JAK1, CYLD, CHMP4B, VPS4BMore
Diamorphinehsa04261Adrenergic signaling in cardiomyocytes4.37E-037P17612, Q13362, Q16537, P0DP23, P17252, P10415, P20020PRKACA, PPP2R5C, PPP2R5E, CALM1, PRKCA, BCL2, ATP2B1More
Diamorphinehsa04350TGF-beta signaling pathway4.88E-021P37173TGFBR2More
Diamorphinehsa04390Hippo signaling pathway1.47E-025P63261, Q13485, Q9UJU2, O43623, Q13489ACTG1, SMAD4, LEF1, SNAI2, BIRC3More
Diamorphinehsa04510Focal adhesion3.21E-026Q15942, P17252, Q13489, P10415, P49767, P63261ZYX, PRKCA, BIRC3, BCL2, VEGFC, ACTG1More
Diamorphinehsa04520Adherens junction3.36E-024Q13485, Q9UJU2, O43623, P63261SMAD4, LEF1, SNAI2, ACTG1More
Diamorphinehsa04540Gap junction4.76E-023P17252, Q13509, P68371PRKCA, TUBB3, TUBB2CMore
Diamorphinehsa04612Antigen processing and presentation1.51E-027P13765, P48382, P26715, P26717, Q13241, O43908, P01732HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8AMore
Diamorphinehsa04613Neutrophil extracellular trap formation2.23E-0314P17252, O60603, P08246, Q92769, P04908, Q6FI13, Q93077, P33778, P68431, P14598, Q15080, P21462, O43315, Q16539PRKCA, TLR2, ELA2, HDAC2, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, H2BC3, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1, AQP9, MAPK14More
Diamorphinehsa04614Renin-angiotensin system1.52E-021P50052AGTR2More
Diamorphinehsa04640Hematopoietic cell lineage1.37E-027P14778, P27930, P11215, P25063, P07766, P01732, P09564IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD7More
Diamorphinehsa04650Natural killer cell mediated cytotoxicity6.78E-0713P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q13241, P26718, O14931, O75015, P26717, P26715PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC1More
Diamorphinehsa04658Th1 and Th2 cell differentiation2.21E-048Q04759, P07766, P20963, P19174, P06239, Q9UL17, P14784, Q13761PRKCQ, CD3E, CD247, PLCG1, LCK, TBX21, IL2RB, RUNX3More
Diamorphinehsa04659Th17 cell differentiation1.25E-038Q04759, P19174, P06239, P14784, P14778, Q9UL17, P07766, P20963PRKCQ, PLCG1, LCK, IL2RB, IL1R1, TBX21, CD3E, CD247More
Diamorphinehsa04660T cell receptor signaling pathway2.21E-0514P01375, Q04759, P42338, O95267, Q08881, P19174, P07766, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, PRKCQ, PIK3CB, RASGRP1, ITK, PLCG1, CD3E, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Diamorphinehsa04666Fc gamma R-mediated phagocytosis2.22E-024P49006, P06396, P14598, P17252MARCKSL1, GSN, NCF1, PRKCAMore
Diamorphinehsa04713Circadian entrainment4.42E-022P0DP23, P17612CALM1, PRKACAMore
Diamorphinehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Diamorphinehsa04720Long-term potentiation8.84E-056P17252, Q16566, P0DP23, O15399, P17612, Q14643PRKCA, CAMK4, CALM1, GRIN2D, PRKACA, ITPR1More
Diamorphinehsa04728Dopaminergic synapse2.18E-039P17612, P14416, P63218, P50151, P49841, Q16539, P49407, Q13362, P0DP23PRKACA, DRD2, GNG5, GNG10, GSK3B, MAPK14, ARRB1, PPP2R5C, CALM1More
Diamorphinehsa04740Olfactory transduction6.71E-032P0DP23, P17612CALM1, PRKACAMore
Diamorphinehsa04750Inflammatory mediator regulation of TRP channels7.24E-035P14778, P19174, P42338, P24723, Q04759IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQMore
Diamorphinehsa04910Insulin signaling pathway3.62E-022P0DP23, P17612CALM1, PRKACAMore
Diamorphinehsa04912GnRH signaling pathway4.42E-023P17252, Q14643, P0DP23PRKCA, ITPR1, CALM1More
Diamorphinehsa04916Melanogenesis2.99E-034P17612, P0DP23, Q9UJU2, P17252PRKACA, CALM1, LEF1, PRKCAMore
Diamorphinehsa04921Oxytocin signaling pathway3.44E-036P0DP23, P17612, P17252, Q16566, P63261, Q96RR4CALM1, PRKACA, PRKCA, CAMK4, ACTG1, CAMKK2More
Diamorphinehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Diamorphinehsa04924Renin secretion1.09E-022P17612, P0DP23PRKACA, CALM1More
Diamorphinehsa04925Aldosterone synthesis and secretion2.90E-046Q14643, P0DP23, P17252, Q16566, P20020, P23634ITPR1, CALM1, PRKCA, CAMK4, ATP2B1, ATP2B4More
Diamorphinehsa04932Non-alcoholic fatty liver disease3.62E-023P49841, Q16718, O14521GSK3B, NDUFA5, SDHDMore
Diamorphinehsa04933AGE-RAGE signaling pathway in diabetic complications3.36E-024Q13485, P10415, P49767, P17252SMAD4, BCL2, VEGFC, PRKCAMore
Diamorphinehsa04966Collecting duct acid secretion3.15E-022P02730, Q9Y666SLC4A1, SLC12A7More
Diamorphinehsa04970Salivary secretion6.19E-056P17612, Q14643, P20020, P23634, P17252, P0DP23PRKACA, ITPR1, ATP2B1, ATP2B4, PRKCA, CALM1More
Diamorphinehsa04971Gastric acid secretion3.94E-034P17612, P17252, P63261, P0DP23PRKACA, PRKCA, ACTG1, CALM1More
Diamorphinehsa04972Pancreatic secretion1.00E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Diamorphinehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Diamorphinehsa04976Bile secretion1.74E-034O43315, P17612, P08183, Q14032AQP9, PRKACA, ABCB1, BAATMore
Diamorphinehsa04978Mineral absorption3.94E-022P23634, Q9BXS9ATP2B4, SLC26A6More
Diamorphinehsa05014Amyotrophic lateral sclerosis4.31E-027O15399, P10415, Q13509, P68371, Q53GS7, P63261, Q9GZY0GRIN2D, BCL2, TUBB3, TUBB2C, GLE1, ACTG1, NXF2; NXF2BMore
Diamorphinehsa05020Prion disease3.80E-024Q16718, O14521, P49841, Q16539NDUFA5, SDHD, GSK3B, MAPK14More
Diamorphinehsa05022Pathways of neurodegeneration - multiple diseases1.24E-026P49841, Q16718, O14521, Q13561, Q16539, Q08752GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPIDMore
Diamorphinehsa05031Amphetamine addiction9.97E-045O15399, P0DP23, Q16566, P17612, P17252GRIN2D, CALM1, CAMK4, PRKACA, PRKCAMore
Diamorphinehsa05034Alcoholism1.29E-023P17612, P0DP23, Q96RR4PRKACA, CALM1, CAMKK2More
Diamorphinehsa05120Epithelial cell signaling in Helicobacter pylori infection2.62E-047Q16539, P09341, P19875, P19174, P25024, P25025, P07948MAPK14, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2, LYNMore
Diamorphinehsa05132Salmonella infection2.12E-0413P51617, Q9UJU2, P63261, Q13546, Q13489, P10415, O75369, O60603, Q9BQS8, P51808, Q13561, Q13509, P68371IRAK1, LEF1, ACTG1, RIPK1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DYNLT3, DCTN2, TUBB3, TUBB2CMore
Diamorphinehsa05133Pertussis2.52E-023P0DP23, P23528, P09871CALM1, CFL1, C1SMore
Diamorphinehsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Diamorphinehsa05135Yersinia infection4.65E-025P13612, P06239, Q16539, P01375, P49841ITGA4, LCK, MAPK14, TNF, GSK3BMore
Diamorphinehsa05140Leishmaniasis1.56E-025P14598, O60603, P49006, P51617, Q15080NCF1, TLR2, MARCKSL1, IRAK1, NCF4More
Diamorphinehsa05144Malaria1.64E-035P60033, O60603, P01375, P35443, P26718CD81, TLR2, TNF, THBS4, KLRK1More
Diamorphinehsa05146Amoebiasis2.21E-048P09341, P19875, P14778, P27930, P42338, P11215, P05089, P12814CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, ACTN1More
Diamorphinehsa05163Human cytomegalovirus infection1.72E-028P01375, P63218, P50151, P49841, P14778, P25025, Q16539, O00463TNF, GNG5, GNG10, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5More
Diamorphinehsa05168Herpes simplex virus 1 infection1.94E-029Q9UKJ0, P01568, Q9GZY0, Q01130, Q13489, Q13398, Q03923, Q9UDV6, P10415PILRB, IFNA21, NXF2; NXF2B, SFRS2, BIRC3, ZNF211, ZNF85, ZNF212, BCL2More
Diamorphinehsa05169Epstein-Barr virus infection2.54E-028Q92769, P04637, Q13546, P10415, P24522, O60603, P51617, P09693HDAC2, TP53, RIPK1, BCL2, GADD45A, TLR2, IRAK1, CD3GMore
Diamorphinehsa05170Human immunodeficiency virus 1 infection6.54E-039P0DP23, P17252, Q13546, Q14643, P51617, O60603, P09693, P10415, Q9Y6Q5CALM1, PRKCA, RIPK1, ITPR1, IRAK1, TLR2, CD3G, BCL2, AP1M2More
Diamorphinehsa05200Pathways in cancer1.51E-0212Q9UJU2, P17252, P43246, Q13485, P14923, P10415, Q13489, P49767, P25116, P78417, P0DP23, P01568LEF1, PRKCA, MSH2, SMAD4, JUP, BCL2, BIRC3, VEGFC, F2R, GSTO1, CALM1, IFNA21More
Diamorphinehsa05212Pancreatic cancer2.97E-033Q15311, P23458, P37173RALBP1, JAK1, TGFBR2More
Diamorphinehsa05214Glioma8.71E-045P0DP23, Q16566, P17252, P04637, P24522CALM1, CAMK4, PRKCA, TP53, GADD45AMore
Diamorphinehsa05216Thyroid cancer1.85E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Diamorphinehsa05217Basal cell carcinoma4.42E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Diamorphinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer8.27E-036P42338, P19174, P07766, P20963, P06239, Q04759PIK3CB, PLCG1, CD3E, CD247, LCK, PRKCQMore
Diamorphinehsa05415Diabetic cardiomyopathy1.28E-024Q16718, O14521, Q16539, P49841NDUFA5, SDHD, MAPK14, GSK3BMore
Diamorphinehsa05418Fluid shear stress and atherosclerosis2.49E-0311Q16539, P78417, P10599, P14780, P01375, P63261, P10415, P14778, P27930, P0DP23, Q92974MAPK14, GSTO1, TXN, MMP9, TNF, ACTG1, BCL2, IL1R1, IL1R2, CALM1, ARHGEF2More
Morphinehsa00052Galactose metabolism1.03E-022P06280, O43451GLA, MGAMMore
Morphinehsa00071Fatty acid degradation4.66E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Morphinehsa00500Starch and sucrose metabolism5.45E-053O43451, P46976, P06737MGAM, GYG1, PYGLMore
Morphinehsa00730Thiamine metabolism7.19E-042P05186, P24666ALPL, ACP1More
Morphinehsa00770Pantothenate and CoA biosynthesis7.90E-033O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Morphinehsa00970Aminoacyl-tRNA biosynthesis1.58E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Morphinehsa00983Drug metabolism - other enzymes2.44E-022P32320, P05164CDA, MPOMore
Morphinehsa01522Endocrine resistance4.51E-022P04637, P42773TP53, CDKN2CMore
Morphinehsa01524Platinum drug resistance1.13E-025P10415, Q13489, P78417, P23025, P43246BCL2, BIRC3, GSTO1, XPA, MSH2More
Morphinehsa03008Ribosome biogenesis in eukaryotes2.60E-035Q9NYH9, P78345, Q9BVP2, O15381, Q9GZY0UTP6, RPP38, GNL3, NVL, NXF2; NXF2BMore
Morphinehsa03013RNA transport2.29E-0413O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, Q9Y6A5, P51114XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, TACC3, FXR1More
Morphinehsa03040Spliceosome5.79E-037Q14562, O43143, O60508, Q99633, Q13595, Q01130, Q9UMS4DHX8, DHX15, CDC40, PRPF18, TRA2A, SFRS2, PRPF19More
Morphinehsa04015Rap1 signaling pathway1.58E-026P20827, P49767, P63261, P25116, P0DP23, P17252EFNA1, VEGFC, ACTG1, F2R, CALM1, PRKCAMore
Morphinehsa04020Calcium signaling pathway1.16E-037Q16566, P17252, O15399, P25116, P0DP23, P23634, P49767CAMK4, PRKCA, GRIN2D, F2R, CALM1, ATP2B4, VEGFCMore
Morphinehsa04024cAMP signaling pathway2.84E-025P0DP23, P23634, Q16566, O15399, P25116CALM1, ATP2B4, CAMK4, GRIN2D, F2RMore
Morphinehsa04062Chemokine signaling pathway3.93E-0310P25024, P25025, P47992, Q9UBD3, P07948, P63218, P50151, P49407, Q08881, P49841CXCR1, CXCR2, XCL1, XCL2, LYN, GNG5, GNG10, ARRB1, ITK, GSK3BMore
Morphinehsa04064NF-kappa B signaling pathway4.92E-026P10415, P51617, Q13546, Q9UDY8, Q13077, P24522BCL2, IRAK1, RIPK1, MALT1, TRAF1, GADD45AMore
Morphinehsa04070Phosphatidylinositol signaling system4.07E-024P0DP23, Q14643, O14732, P17252CALM1, ITPR1, IMPA2, PRKCAMore
Morphinehsa04071Sphingolipid signaling pathway1.82E-049P17252, Q9H228, P01375, Q13362, Q16537, Q9BX95, P04637, P10415, Q9UQC2PRKCA, EDG8, TNF, PPP2R5C, PPP2R5E, SGPP1, TP53, BCL2, GAB2More
Morphinehsa04110Cell cycle1.29E-024P30260, P04637, P49918, P42773CDC27, TP53, CDKN1C, CDKN2CMore
Morphinehsa04145Phagosome1.86E-025P63261, Q15080, Q13509, P68371, P27824ACTG1, NCF4, TUBB3, TUBB2C, CANXMore
Morphinehsa04151PI3K-Akt signaling pathway4.57E-023P04637, Q96BR1, P56279TP53, SGK3, TCL1AMore
Morphinehsa04210Apoptosis3.58E-024O76075, P01375, Q9NR28, Q16548DFFB, TNF, DIABLO, BCL2A1More
Morphinehsa04213Longevity regulating pathway - multiple species2.85E-022Q9Y4H2, Q13547IRS2, HDAC1More
Morphinehsa04261Adrenergic signaling in cardiomyocytes3.44E-025Q16537, P0DP23, P17252, P10415, P20020PPP2R5E, CALM1, PRKCA, BCL2, ATP2B1More
Morphinehsa04340Hedgehog signaling pathway3.32E-022P49841, P22694GSK3B, PRKACBMore
Morphinehsa04350TGF-beta signaling pathway4.88E-021P37173TGFBR2More
Morphinehsa04390Hippo signaling pathway1.47E-025P63261, Q13485, Q9UJU2, O43623, Q13489ACTG1, SMAD4, LEF1, SNAI2, BIRC3More
Morphinehsa04510Focal adhesion3.21E-026Q15942, P17252, Q13489, P10415, P49767, P63261ZYX, PRKCA, BIRC3, BCL2, VEGFC, ACTG1More
Morphinehsa04520Adherens junction3.36E-024Q13485, Q9UJU2, O43623, P63261SMAD4, LEF1, SNAI2, ACTG1More
Morphinehsa04540Gap junction4.76E-023P17252, Q13509, P68371PRKCA, TUBB3, TUBB2CMore
Morphinehsa04612Antigen processing and presentation1.51E-027P13765, P48382, P26715, P26717, Q13241, O43908, P01732HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, KLRC4, CD8AMore
Morphinehsa04613Neutrophil extracellular trap formation2.98E-0414P17252, P11215, O60603, P08246, Q13547, Q92769, Q6FI13, P58876, P33778, Q16778, O60814, P14598, Q15080, P21462PRKCA, ITGAM, TLR2, ELA2, HDAC1, HDAC2, H2AC18; H2AC19, H2BC5, H2BC3, HIST2H2BE, H2BC12, NCF1, NCF4, FPR1More
Morphinehsa04614Renin-angiotensin system1.52E-021P50052AGTR2More
Morphinehsa04650Natural killer cell mediated cytotoxicity7.01E-0510P01375, P78314, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, P26715TNF, SH3BP2, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Morphinehsa04657IL-17 signaling pathway3.31E-023P49841, P14780, P01375GSK3B, MMP9, TNFMore
Morphinehsa04660T cell receptor signaling pathway1.49E-0310P01375, O95267, Q08881, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Morphinehsa04666Fc gamma R-mediated phagocytosis2.22E-024P49006, P06396, P14598, P17252MARCKSL1, GSN, NCF1, PRKCAMore
Morphinehsa04720Long-term potentiation3.70E-045P17252, Q16566, P0DP23, O15399, Q14643PRKCA, CAMK4, CALM1, GRIN2D, ITPR1More
Morphinehsa04728Dopaminergic synapse2.82E-026P14416, P63218, P50151, P49841, Q16539, P49407DRD2, GNG5, GNG10, GSK3B, MAPK14, ARRB1More
Morphinehsa04910Insulin signaling pathway2.35E-023P22694, P06737, P49841PRKACB, PYGL, GSK3BMore
Morphinehsa04912GnRH signaling pathway4.42E-023P17252, Q14643, P0DP23PRKCA, ITPR1, CALM1More
Morphinehsa04916Melanogenesis3.55E-023P0DP23, Q9UJU2, P17252CALM1, LEF1, PRKCAMore
Morphinehsa04919Thyroid hormone signaling pathway7.11E-034P49841, P22694, O60244, Q9NVC6GSK3B, PRKACB, MED14, MED17More
Morphinehsa04921Oxytocin signaling pathway4.19E-024P0DP23, P17252, Q16566, P63261CALM1, PRKCA, CAMK4, ACTG1More
Morphinehsa04925Aldosterone synthesis and secretion2.90E-046Q14643, P0DP23, P17252, Q16566, P20020, P23634ITPR1, CALM1, PRKCA, CAMK4, ATP2B1, ATP2B4More
Morphinehsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Morphinehsa04933AGE-RAGE signaling pathway in diabetic complications3.36E-024Q13485, P10415, P49767, P17252SMAD4, BCL2, VEGFC, PRKCAMore
Morphinehsa04966Collecting duct acid secretion3.15E-022P02730, Q9Y666SLC4A1, SLC12A7More
Morphinehsa04970Salivary secretion8.71E-045Q14643, P20020, P23634, P17252, P0DP23ITPR1, ATP2B1, ATP2B4, PRKCA, CALM1More
Morphinehsa04971Gastric acid secretion4.76E-023P17252, P63261, P0DP23PRKCA, ACTG1, CALM1More
Morphinehsa04972Pancreatic secretion1.00E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Morphinehsa04976Bile secretion2.44E-022P22694, P08183PRKACB, ABCB1More
Morphinehsa04978Mineral absorption3.94E-022P23634, Q9BXS9ATP2B4, SLC26A6More
Morphinehsa05014Amyotrophic lateral sclerosis4.31E-027O15399, P10415, Q13509, P68371, Q53GS7, P63261, Q9GZY0GRIN2D, BCL2, TUBB3, TUBB2C, GLE1, ACTG1, NXF2; NXF2BMore
Morphinehsa05031Amphetamine addiction1.49E-024O15399, P0DP23, Q16566, P17252GRIN2D, CALM1, CAMK4, PRKCAMore
Morphinehsa05034Alcoholism2.10E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Morphinehsa05120Epithelial cell signaling in Helicobacter pylori infection3.11E-024Q16539, P25024, P25025, P07948MAPK14, CXCR1, CXCR2, LYNMore
Morphinehsa05132Salmonella infection2.12E-0413P51617, Q9UJU2, P63261, Q13546, Q13489, P10415, O75369, O60603, Q9BQS8, P51808, Q13561, Q13509, P68371IRAK1, LEF1, ACTG1, RIPK1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DYNLT3, DCTN2, TUBB3, TUBB2CMore
Morphinehsa05133Pertussis2.52E-023P0DP23, P23528, P09871CALM1, CFL1, C1SMore
Morphinehsa05135Yersinia infection4.65E-025P13612, P06239, Q16539, P01375, P49841ITGA4, LCK, MAPK14, TNF, GSK3BMore
Morphinehsa05140Leishmaniasis1.56E-025P14598, O60603, P49006, P51617, Q15080NCF1, TLR2, MARCKSL1, IRAK1, NCF4More
Morphinehsa05144Malaria1.64E-035P60033, O60603, P01375, P35443, P26718CD81, TLR2, TNF, THBS4, KLRK1More
Morphinehsa05163Human cytomegalovirus infection1.72E-028P01375, P63218, P50151, P49841, P14778, P25025, Q16539, O00463TNF, GNG5, GNG10, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5More
Morphinehsa05168Herpes simplex virus 1 infection1.94E-029Q9UKJ0, P01568, Q9GZY0, Q01130, Q13489, Q13398, Q03923, Q9UDV6, P10415PILRB, IFNA21, NXF2; NXF2B, SFRS2, BIRC3, ZNF211, ZNF85, ZNF212, BCL2More
Morphinehsa05169Epstein-Barr virus infection2.54E-028Q92769, P04637, Q13546, P10415, P24522, O60603, P51617, P09693HDAC2, TP53, RIPK1, BCL2, GADD45A, TLR2, IRAK1, CD3GMore
Morphinehsa05170Human immunodeficiency virus 1 infection6.54E-039P0DP23, P17252, Q13546, Q14643, P51617, O60603, P09693, P10415, Q9Y6Q5CALM1, PRKCA, RIPK1, ITPR1, IRAK1, TLR2, CD3G, BCL2, AP1M2More
Morphinehsa05200Pathways in cancer1.51E-0212Q9UJU2, P17252, P43246, Q13485, P14923, P10415, Q13489, P49767, P25116, P78417, P0DP23, P01568LEF1, PRKCA, MSH2, SMAD4, JUP, BCL2, BIRC3, VEGFC, F2R, GSTO1, CALM1, IFNA21More
Morphinehsa05202Transcriptional misregulation in cancer1.24E-024P27930, P11215, Q13547, P12980IL1R2, ITGAM, HDAC1, LYL1More
Morphinehsa05203Viral carcinogenesis6.44E-034Q13547, P58876, Q16778, O60814HDAC1, H2BC5, HIST2H2BE, H2BC12More
Morphinehsa05212Pancreatic cancer3.40E-021P37173TGFBR2More
Morphinehsa05214Glioma8.71E-045P0DP23, Q16566, P17252, P04637, P24522CALM1, CAMK4, PRKCA, TP53, GADD45AMore
Morphinehsa05216Thyroid cancer1.85E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Morphinehsa05217Basal cell carcinoma4.42E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Morphinehsa05322Systemic lupus erythematosus1.18E-023P58876, Q16778, O60814H2BC5, HIST2H2BE, H2BC12More
Morphinehsa05418Fluid shear stress and atherosclerosis2.49E-0311Q16539, P78417, P10599, P14780, P01375, P63261, P10415, P14778, P27930, P0DP23, Q92974MAPK14, GSTO1, TXN, MMP9, TNF, ACTG1, BCL2, IL1R1, IL1R2, CALM1, ARHGEF2More

Community members of Morphine (SDC: 2.18)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
O15245SLC22A1Solute carrier family 22 member 1Predicted00.014910.02192.0294
Q9UEE5STK17ASerine/threonineNoneprotein kinase 17APredicted00.35040.337600.8504
P50052AGTR2TypeNone2 angiotensin II receptorPredicted10.06040.43650.15411.0572
P21462FPR1fMetNoneLeuNonePhe receptorPredicted00.12050.34920.43781.1964
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P25024CXCR1CNoneXNoneC chemokine receptor type 1Predicted10.16560.42320.40091.33
P51684CCR6CNoneC chemokine receptor type 6Predicted00.0850.17410.33040.7212
P46091GPR1ChemerinNonelike receptor 2Predicted00.24760.137200.3982
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)
DRD2P14416IC504.2
DRD2P14416Ki0.62
DRD2P14416Ki3.6
DRD2P14416Ki26
DRD2P14416Kd0.66
DRD2P14416Kd24
DRD2P14416Kd127