PharmaCoNets of Minoxidil (SPCN: 5.85 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Minoxidilhsa00071Fatty acid degradation2.52E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Minoxidilhsa00500Starch and sucrose metabolism1.07E-033O43451, P46976, P06737MGAM, GYG1, PYGLMore
Minoxidilhsa00630Glyoxylate and dicarboxylate metabolism2.18E-052P40925, P15104MDH1, GLULMore
Minoxidilhsa00730Thiamine metabolism8.96E-043Q9Y6K8, P05186, P24666AK5, ALPL, ACP1More
Minoxidilhsa00760Nicotinate and nicotinamide metabolism3.52E-021P21589NT5EMore
Minoxidilhsa00770Pantothenate and CoA biosynthesis2.27E-022O95498, O95497VNN2, VNN1More
Minoxidilhsa00970Aminoacyl-tRNA biosynthesis2.77E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Minoxidilhsa01100Metabolic pathways3.52E-0223P05089, O95455, P21953, P32320, P11766, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, Q08477, P15907, Q9UNP4, P37837, P32321, Q9BPW9, Q9UHY7, P43490, P46976, P06737ARG1, TGDS, BCKDHB, CDA, ADH5, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, CYP4F3, ST6GAL1, ST3GAL5, TALDO1, DCTD, DHRS9, ENOPH1, PBEF1, GYG1, PYGLMore
Minoxidilhsa03040Spliceosome4.19E-025Q14562, O60508, P08579, Q01130, O43447DHX8, CDC40, SNRPB2, SFRS2, PPIHMore
Minoxidilhsa04060Cytokine-cytokine receptor interaction4.71E-022P78552, O75509IL13RA1, TNFRSF21More
Minoxidilhsa04072Phospholipase D signaling pathway9.70E-032Q92529, Q14344SHC3, GNA13More
Minoxidilhsa04150mTOR signaling pathway2.23E-023P42338, Q13322, P49841PIK3CB, GRB10, GSK3BMore
Minoxidilhsa04380Osteoclast differentiation4.80E-024P06239, P42338, P14778, Q8N149LCK, PIK3CB, IL1R1, LILRA2More
Minoxidilhsa04621NOD-like receptor signaling pathway1.93E-028Q16539, P10599, Q9H1Y0, P43490, O00463, P01375, P09341, P12838MAPK14, TXN, ATG5, PBEF1, TRAF5, TNF, CXCL1, DEFA4More
Minoxidilhsa04657IL-17 signaling pathway1.03E-026O00463, Q16539, P49841, P09341, P14780, P01375TRAF5, MAPK14, GSK3B, CXCL1, MMP9, TNFMore
Minoxidilhsa04659Th17 cell differentiation4.12E-024P06239, P14784, P14778, P07766LCK, IL2RB, IL1R1, CD3EMore
Minoxidilhsa04662B cell receptor signaling pathway3.05E-056P49841, P42338, P60033, P07948, P21854, Q8N149GSK3B, PIK3CB, CD81, LYN, CD72, LILRA2More
Minoxidilhsa04664Fc epsilon RI signaling pathway2.32E-023P42338, P07948, P09917PIK3CB, LYN, ALOX5More
Minoxidilhsa04724Glutamatergic synapse5.94E-034O15399, P63218, P50151, P15104GRIN2D, GNG5, GNG10, GLULMore
Minoxidilhsa04725Cholinergic synapse4.10E-023P63218, P50151, P42338GNG5, GNG10, PIK3CBMore
Minoxidilhsa04727GABAergic synapse1.63E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
Minoxidilhsa04730Long-term depression3.52E-021Q14344GNA13More
Minoxidilhsa04750Inflammatory mediator regulation of TRP channels3.72E-023P14778, P42338, P24723IL1R1, PIK3CB, PRKCHMore
Minoxidilhsa04926Relaxin signaling pathway5.70E-035P42338, P63218, P50151, P49767, P49407PIK3CB, GNG5, GNG10, VEGFC, ARRB1More
Minoxidilhsa04929GnRH secretion3.30E-032P42338, P49407PIK3CB, ARRB1More
Minoxidilhsa04960Aldosterone-regulated sodium reabsorption4.38E-021P48048KCNJ1More
Minoxidilhsa04973Carbohydrate digestion and absorption4.12E-032O43451, P42338MGAM, PIK3CBMore
Minoxidilhsa05120Epithelial cell signaling in Helicobacter pylori infection2.27E-024Q16539, P09341, P25024, P25025MAPK14, CXCL1, CXCR1, CXCR2More
Minoxidilhsa05140Leishmaniasis2.47E-025P13612, O75015, P01375, P49006, Q16539ITGA4, FCGR3B, TNF, MARCKSL1, MAPK14More
Minoxidilhsa05146Amoebiasis4.20E-025P09341, P14778, P27930, P01375, P05089CXCL1, IL1R1, IL1R2, TNF, ARG1More
Minoxidilhsa05163Human cytomegalovirus infection3.28E-027P01375, P50151, P49841, P14778, P25025, Q16539, O00463TNF, GNG10, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5More
Minoxidilhsa05169Epstein-Barr virus infection3.72E-026Q13547, P42338, P07948, Q13761, O75293, P07766HDAC1, PIK3CB, LYN, RUNX3, GADD45B, CD3EMore
Minoxidilhsa05225Hepatocellular carcinoma1.85E-022Q92529, P51531SHC3, SMARCA2More
Minoxidilhsa05418Fluid shear stress and atherosclerosis2.43E-037Q16539, P42338, P10599, P14780, P01375, P14778, P27930MAPK14, PIK3CB, TXN, MMP9, TNF, IL1R1, IL1R2More

Community members of Minoxidil (SDC: 1.67)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P48048KCNJ1ATPNonesensitive inward rectifier potassium channel 1Reported00.00420.2820.12740.6935
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
P78508KCNJ10ATPNonesensitive inward rectifier potassium channel 10Predicted00.07310.08780.20670.4189
Q99712KCNJ15ATPNonesensitive inward rectifier potassium channel 15Predicted00.15870.07790.12670.3619
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)