PharmaCoNets

PharmaCoNets of Miconazole (S_PCN: 64.96 )

Miconazole regulated-network (S_DN: 17.90)

Drug Name

Pathway ID

Pathway name

P-value

No. of gene members

UniProt AC

Gene name

Detail of Coexpression

Miconazole

hsa00052

Galactose metabolism

1.03E-02

P06280, O43451

GLA, MGAM

Miconazole

hsa00053

Ascorbate and aldarate metabolism

5.61E-03

P51648, Q9UEF7

ALDH3A2, KL

Miconazole

hsa00061

Fatty acid biosynthesis

4.83E-02

P33121

ACSL1

Miconazole

hsa00071

Fatty acid degradation

2.52E-02

O75521, P11766, P33121

ECI2, ADH5, ACSL1

Miconazole

hsa00190

Oxidative phosphorylation

3.50E-02

Q16718, Q13488

NDUFA5, TCIRG1

Miconazole

hsa00220

Arginine biosynthesis

1.97E-02

P15104, P49448

GLUL, GLUD2

Miconazole

hsa00250

Alanine, aspartate and glutamate metabolism

1.97E-02

P49448, P15104

GLUD2, GLUL

Miconazole

hsa00280

Valine, leucine and isoleucine degradation

4.55E-02

P21953, P51648

BCKDHB, ALDH3A2

Miconazole

hsa00500

Starch and sucrose metabolism

1.67E-06

O43451, P46976, P06737

MGAM, GYG1, PYGL

Miconazole

hsa00533

Glycosaminoglycan biosynthesis - keratan sulfate

3.43E-02

Q9NY97

B3GNT2

Miconazole

hsa00590

Arachidonic acid metabolism

3.85E-02

P11712, P09960

CYP2C9, LTA4H

Miconazole

hsa00591

Linoleic acid metabolism

4.07E-02

P11712

CYP2C9

Miconazole

hsa00600

Sphingolipid metabolism

3.01E-02

Q9BX95, P06280

SGPP1, GLA

Miconazole

hsa00604

Glycosphingolipid biosynthesis - ganglio series

1.34E-02

P06865, Q9H4F1

HEXA, ST6GALNAC4

Miconazole

hsa00620

Pyruvate metabolism

4.20E-02

P40926, P14550

MDH2, AKR1A1

Miconazole

hsa00630

Glyoxylate and dicarboxylate metabolism

6.37E-05

P40925, P15104

MDH1, GLUL

Miconazole

hsa00640

Propanoate metabolism

3.83E-02

Q02252, Q9P2R7

ALDH6A1, SUCLA2

Miconazole

hsa00730

Thiamine metabolism

1.03E-06

Q9Y6K8, P05186, P24666

AK5, ALPL, ACP1

Miconazole

hsa00760

Nicotinate and nicotinamide metabolism

3.52E-02

P21589

NT5E

Miconazole

hsa00770

Pantothenate and CoA biosynthesis

2.27E-02

O95498, O95497

VNN2, VNN1

Miconazole

hsa00910

Nitrogen metabolism

1.97E-02

P15104, P49448

GLUL, GLUD2

Miconazole

hsa00970

Aminoacyl-tRNA biosynthesis

7.63E-06

O95363, P54136, P14868, Q15046

FARS2, RARS1, DARS, KARS

Miconazole

hsa00980

Metabolism of xenobiotics by cytochrome P450

9.14E-03

P78417, P11712

GSTO1, CYP2C9

Miconazole

hsa00982

Drug metabolism - cytochrome P450

9.14E-03

P11712, P78417

CYP2C9, GSTO1

Miconazole

hsa00983

Drug metabolism - other enzymes

2.44E-02

P32320, P05164

CDA, MPO

Miconazole

hsa01100

Metabolic pathways

5.95E-03

P05089, O95455, P21953, P15144, P32320, P11766, P06280, Q16875, O43286, O43451, P05186, P24666, Q9HCC0, P33121, P42330, Q13093, Q08477, P15907, Q9NY28, Q9UNP4, Q9BX95, P09960, P37837, P32321, Q9BPW9, Q9UHY7, P43490, P46976, P06737, Q16718

ARG1, TGDS, BCKDHB, ANPEP, CDA, ADH5, GLA, PFKFB3, B4GALT5, MGAM, ALPL, ACP1, MCCC2, ACSL1, AKR1C3, PLA2G7, CYP4F3, ST6GAL1, GALNT8, ST3GAL5, SGPP1, LTA4H, TALDO1, DCTD, DHRS9, ENOPH1, PBEF1, GYG1, PYGL, NDUFA5

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P05089	ARG1	Arginase-1	0.807
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	O95455	TGDS	dTDP-D-glucose 4,6-dehydratase	-0.716
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P21953	BCKDHB	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial	-0.709
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	P15144	ANPEP	Aminopeptidase N	0.763
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	P32320	CDA	Cytidine deaminase	0.706
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P32320	CDA	Cytidine deaminase	0.714
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P11766	ADH5	Alcohol dehydrogenase class-3	-0.857
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	P06280	GLA	Alpha-galactosidase A	0.764
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P06280	GLA	Alpha-galactosidase A	0.706
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	Q16875	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	0.919
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	O43286	B4GALT5	Beta-1,4-galactosyltransferase 5	0.779
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	O43451	MGAM	Maltase-glucoamylase	0.925
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	0.883
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	-0.709
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P24666	ACP1	Low molecular weight phosphotyrosine protein phosphatase	-0.715
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	Q9HCC0	MCCC2	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	-0.71
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	P33121	ACSL1	Long-chain-fatty-acid--CoA ligase 1	0.734
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P33121	ACSL1	Long-chain-fatty-acid--CoA ligase 1	0.74
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	P42330	AKR1C3	Aldo-keto reductase family 1 member C3	-0.708
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	Q13093	PLA2G7	Platelet-activating factor acetylhydrolase	-0.7
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	Q08477	CYP4F3	Cytochrome P450 4F3	0.793
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P15907	ST6GAL1	Beta-galactoside alpha-2,6-sialyltransferase 1	-0.722
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	Q9NY28	GALNT8	Probable polypeptide N-acetylgalactosaminyltransferase 8	-0.795
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	Q9UNP4	ST3GAL5	Lactosylceramide alpha-2,3-sialyltransferase	-0.726
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	Q9BX95	SGPP1	Sphingosine-1-phosphate phosphatase 1	-0.713
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	P09960	LTA4H	Leukotriene A-4 hydrolase	0.772
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P37837	TALDO1	Transaldolase	0.843
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P32321	DCTD	Deoxycytidylate deaminase	-0.737
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	Q9BPW9	DHRS9	Dehydrogenase/reductase SDR family member 9	0.899
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	Q9UHY7	ENOPH1	Enolase-phosphatase E1	-0.709
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P43490	PBEF1	Nicotinamide phosphoribosyltransferase	0.899
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P46976	GYG1	Glycogenin-1	0.866
Q99712	KCNJ15	ATP-sensitive inward rectifier potassium channel 15	P06737	PYGL	Glycogen phosphorylase, liver form	0.783
P16389	KCNA2	Potassium voltage-gated channel subfamily A member 2	Q16718	NDUFA5	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	-0.837

Miconazole

hsa03010

Ribosome

3.56E-06

P62753, P42677, P32969, P40429, P62917, P46776, Q9H0U6, Q07020, P62910, Q02878, P36578, P05386, P62249, P23396

RPS6, RPS27, RPL9, RPL13A, RPL8, RPL27A, MRPL18, RPL18, RPL32, RPL6, RPL4, RPLP1, RPS16, RPS3

Miconazole

hsa03020

RNA polymerase

9.86E-07

Q9GZM3, P52435

POLR2J2, POLR2J

Miconazole

hsa03040

Spliceosome

4.19E-04

Q14562, O43143, O60508, P08579, Q07955, Q01130, Q13243, P11142, O43447, O75643

DHX8, DHX15, CDC40, SNRPB2, SFRS1, SFRS2, SFRS5, HSPA8, PPIH, ASCC3L1

Miconazole

hsa04012

ErbB signaling pathway

1.34E-02

P16333, P19174, P42338, P01106

NCK1, PLCG1, PIK3CB, MYC

Miconazole

hsa04014

Ras signaling pathway

2.92E-04

P42338, P20827, Q9NRA1, P49767, Q13009, P0DP23, P62873, P63218, P50151, P19174

PIK3CB, EFNA1, PDGFC, VEGFC, TIAM1, CALM1, GNB1, GNG5, GNG10, PLCG1

Miconazole

hsa04015

Rap1 signaling pathway

4.83E-03

P20827, Q9NRA1, P49767, P11215, Q13009, P42338, P0DP23, P19174

EFNA1, PDGFC, VEGFC, ITGAM, TIAM1, PIK3CB, CALM1, PLCG1

Miconazole

hsa04020

Calcium signaling pathway

2.61E-02

P27987, P21796, P19174, P0DP23, Q9NRA1, P49767

ITPKB, VDAC1, PLCG1, CALM1, PDGFC, VEGFC

Miconazole

hsa04024

cAMP signaling pathway

1.53E-02

P49019, P22694, P20020, P48058

HCAR3, PRKACB, ATP2B1, GRIA4

Miconazole

hsa04060

Cytokine-cytokine receptor interaction

4.71E-02

P78552, O75509

IL13RA1, TNFRSF21

Miconazole

hsa04062

Chemokine signaling pathway

3.26E-04

P07948, P42338, P19174, P62873, P63218, P50151, P43250, Q13009, P14598, P42224, P25963

LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, TIAM1, NCF1, STAT1, NFKBIA

Miconazole

hsa04070

Phosphatidylinositol signaling system

1.12E-02

P19174, P0DP23, P42338, P23743, P27987

PLCG1, CALM1, PIK3CB, DGKA, ITPKB

Miconazole

hsa04071

Sphingolipid signaling pathway

1.94E-02

Q9H228, P01375, Q9UQC2

EDG8, TNF, GAB2

Miconazole

hsa04072

Phospholipase D signaling pathway

5.48E-03

P42338, Q92529, P19174, Q14344, P23743, Q9NRA1

PIK3CB, SHC3, PLCG1, GNA13, DGKA, PDGFC

Miconazole

hsa04114

Oocyte meiosis

1.33E-02

P51812, Q02750, P16298, Q17RY0

RPS6KA3, MAP2K1, PPP3CB, CPEB4

Miconazole

hsa04141

Protein processing in endoplasmic reticulum

9.57E-03

P30101, P49257, P60604, Q9H173

PDIA3, LMAN1, UBE2G2, SIL1

Miconazole

hsa04145

Phagosome

2.75E-02

Q15080, P14598, P68371, Q13488

NCF4, NCF1, TUBB2C, TCIRG1

Miconazole

hsa04150

mTOR signaling pathway

2.23E-03

P42338, Q02750, Q9NQL2, P51812, Q13322, P49841

PIK3CB, MAP2K1, RRAGD, RPS6KA3, GRB10, GSK3B

Miconazole

hsa04151

PI3K-Akt signaling pathway

7.63E-04

P42338, P43657, P01106, P09603, P20827, Q9NRA1, P49767, Q9GZP0, P08238, P62873, P63218, P50151, P13612, O15335, Q13751, P14784, P01568

PIK3CB, P2RY5, MYC, CSF1, EFNA1, PDGFC, VEGFC, PDGFD, HSP90AB1, GNB1, GNG5, GNG10, ITGA4, CHAD, LAMB3, IL2RB, IFNA21

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	-0.805
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	P43657	P2RY5	Lysophosphatidic acid receptor 6	0.702
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P01106	MYC	Myc proto-oncogene protein	0.719
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	P09603	CSF1	Macrophage colony-stimulating factor 1	-0.789
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P20827	EFNA1	Ephrin-A1	-0.743
P40925	MDH1	Malate dehydrogenase, cytoplasmic	Q9NRA1	PDGFC	Platelet-derived growth factor C	-0.702
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P49767	VEGFC	Vascular endothelial growth factor C	-0.778
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	Q9GZP0	PDGFD	Platelet-derived growth factor D	0.736
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.926
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P62873	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.764
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	-0.844
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P63218	GNG5	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5	-0.846
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	P50151	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	-0.902
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P50151	GNG10	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10	-0.799
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	P13612	ITGA4	Integrin alpha-4	0.77
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	O15335	CHAD	Chondroadherin	-0.729
P40925	MDH1	Malate dehydrogenase, cytoplasmic	O15335	CHAD	Chondroadherin	-0.704
P61088	UBE2N	Ubiquitin-conjugating enzyme E2 N	Q13751	LAMB3	Laminin subunit beta-3	-0.794
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.912
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P01568	IFNA21	Interferon alpha-21	-0.701

Miconazole

hsa04210

Apoptosis

3.58E-02

O76075, P01375, Q9NR28, Q16548

DFFB, TNF, DIABLO, BCL2A1

Miconazole

hsa04215

Apoptosis - multiple species

1.56E-02

Q13489, P10415

BIRC3, BCL2

Miconazole

hsa04217

Necroptosis

1.70E-02

P01568, Q13489, P08238, O43633, Q08752

IFNA21, BIRC3, HSP90AB1, CHMP2A, PPID

Miconazole

hsa04340

Hedgehog signaling pathway

3.32E-02

P49841, P22694

GSK3B, PRKACB

Miconazole

hsa04360

Axon guidance

2.87E-02

P16333, P20827, O95631, P42338, P19174

NCK1, EFNA1, NTN1, PIK3CB, PLCG1

Miconazole

hsa04370

VEGF signaling pathway

2.68E-03

P16298, Q05397, Q02750

PPP3CB, PTK2, MAP2K1

Miconazole

hsa04371

Apelin signaling pathway

2.41E-03

P62873, P63218, P50151, Q13370, Q14814, Q14344, P0DP23

GNB1, GNG5, GNG10, PDE3B, MEF2D, GNA13, CALM1

Miconazole

hsa04380

Osteoclast differentiation

4.80E-02

P06239, P42338, P14778, Q8N149

LCK, PIK3CB, IL1R1, LILRA2

Miconazole

hsa04390

Hippo signaling pathway

2.08E-02

P84022, Q13485, Q13489

SMAD3, SMAD4, BIRC3

Miconazole

hsa04512

ECM-receptor interaction

4.41E-02

Q13751, P13612, O15335

LAMB3, ITGA4, CHAD

Miconazole

hsa04530

Tight junction

3.29E-02

P16989, P56750, Q14247

CSDA, CLDN17, CTTN

Miconazole

hsa04610

Complement and coagulation cascades

4.69E-03

P0C0L4

C4A

Miconazole

hsa04613

Neutrophil extracellular trap formation

2.06E-03

P42338, P19174, P11215, Q13547, Q93077, P62807, Q93079, O60814, P68431, P21796, P14598

PIK3CB, PLCG1, ITGAM, HDAC1, HIST1H2AC, HIST1H2BC, H2BC9, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, VDAC1, NCF1

Miconazole

hsa04620

Toll-like receptor signaling pathway

4.00E-02

P01568, P42224, P25963, P42338

IFNA21, STAT1, NFKBIA, PIK3CB

Miconazole

hsa04621

NOD-like receptor signaling pathway

1.93E-02

Q16539, P10599, Q9H1Y0, P43490, O00463, P01375, P09341, P12838

MAPK14, TXN, ATG5, PBEF1, TRAF5, TNF, CXCL1, DEFA4

Miconazole

hsa04623

Cytosolic DNA-sensing pathway

3.67E-02

P01568, P25963

IFNA21, NFKBIA

Miconazole

hsa04625

C-type lectin receptor signaling pathway

2.17E-02

Q9ULY5, P42224, P25963, P42338, P0DP23

CLEC4E, STAT1, NFKBIA, PIK3CB, CALM1

Miconazole

hsa04650

Natural killer cell mediated cytotoxicity

2.78E-04

P16298, P50591, P17252, P78314, P06239, O60880, P20963, Q02750, P26718, O75015, P26717, P26715

PPP3CB, TNFSF10, PRKCA, SH3BP2, LCK, SH2D1A, CD247, MAP2K1, KLRK1, FCGR3B, KLRC2, KLRC1

Miconazole

hsa04657

IL-17 signaling pathway

1.07E-03

O00463, Q16539, P49841, P09341, P14780, P01375

TRAF5, MAPK14, GSK3B, CXCL1, MMP9, TNF

Miconazole

hsa04658

Th1 and Th2 cell differentiation

2.45E-04

P25963, P07766, P20963, P09693, Q16539, P19174, P06239, P42224, Q9UL17, P14784, P13765, Q13761

NFKBIA, CD3E, CD247, CD3G, MAPK14, PLCG1, LCK, STAT1, TBX21, IL2RB, HLA-DOB, RUNX3

Miconazole

hsa04659

Th17 cell differentiation

1.01E-05

P25963, Q16539, P19174, P06239, P42224, P14784, P13765, P14778, Q9UL17, P84022, Q13485, P08238, P07766, P09693, P20963

NFKBIA, MAPK14, PLCG1, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, TBX21, SMAD3, SMAD4, HSP90AB1, CD3E, CD3G, CD247

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
O75469	NR1I2	Nuclear receptor subfamily 1 group I member 2	P25963	NFKBIA	NF-kappa-B inhibitor alpha	-0.728
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P25963	NFKBIA	NF-kappa-B inhibitor alpha	0.711
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	Q16539	MAPK14	Mitogen-activated protein kinase 14	0.901
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P19174	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	0.932
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P06239	LCK	Tyrosine-protein kinase Lck	-0.709
P78508	KCNJ10	ATP-sensitive inward rectifier potassium channel 10	P06239	LCK	Tyrosine-protein kinase Lck	0.753
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.838
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.912
P78508	KCNJ10	ATP-sensitive inward rectifier potassium channel 10	P14784	IL2RB	Interleukin-2 receptor subunit beta	0.829
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P13765	HLA-DOB	HLA class II histocompatibility antigen, DO beta chain	-0.731
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P14778	IL1R1	Interleukin-1 receptor type 1	0.909
P78508	KCNJ10	ATP-sensitive inward rectifier potassium channel 10	P14778	IL1R1	Interleukin-1 receptor type 1	-0.877
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	Q9UL17	TBX21	T-box transcription factor TBX21	-0.73
O75469	NR1I2	Nuclear receptor subfamily 1 group I member 2	P84022	SMAD3	Mothers against decapentaplegic homolog 3	0.769
O75469	NR1I2	Nuclear receptor subfamily 1 group I member 2	Q13485	SMAD4	Mothers against decapentaplegic homolog 4	-0.721
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P08238	HSP90AB1	Heat shock protein HSP 90-beta	0.926
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P07766	CD3E	T-cell surface glycoprotein CD3 epsilon chain	0.839
P78508	KCNJ10	ATP-sensitive inward rectifier potassium channel 10	P07766	CD3E	T-cell surface glycoprotein CD3 epsilon chain	0.819
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P09693	CD3G	T-cell surface glycoprotein CD3 gamma chain	-0.734
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P20963	CD247	T-cell surface glycoprotein CD3 zeta chain	-0.703

Miconazole

hsa04662

B cell receptor signaling pathway

2.54E-04

P25963, P49841, P42338, P07948, P21854, Q8N149

NFKBIA, GSK3B, PIK3CB, LYN, CD72, LILRA2

Miconazole

hsa04664

Fc epsilon RI signaling pathway

1.34E-02

P42338, P07948, P19174, P09917

PIK3CB, LYN, PLCG1, ALOX5

Miconazole

hsa04666

Fc gamma R-mediated phagocytosis

2.92E-02

P07948, P42338, P19174, P14598

LYN, PIK3CB, PLCG1, NCF1

Miconazole

hsa04710

Circadian rhythm

1.67E-02

Q16526, Q9Y478

CRY1, PRKAB1

Miconazole

hsa04713

Circadian entrainment

2.24E-03

P0DP23, P17252, P62873, P63218, P50151, P48058, P22694

CALM1, PRKCA, GNB1, GNG5, GNG10, GRIA4, PRKACB

Miconazole

hsa04714

Thermogenesis

3.16E-02

P22694, P33121, Q16718

PRKACB, ACSL1, NDUFA5

Miconazole

hsa04720

Long-term potentiation

1.38E-02

P16298, P51812, Q02750

PPP3CB, RPS6KA3, MAP2K1

Miconazole

hsa04721

Synaptic vesicle cycle

1.14E-02

Q13488, P31645

TCIRG1, SLC6A4

Miconazole

hsa04723

Retrograde endocannabinoid signaling

1.20E-03

P17252, P48058, P22694, Q16718

PRKCA, GRIA4, PRKACB, NDUFA5

Miconazole

hsa04724

Glutamatergic synapse

3.53E-05

P48058, O15399, P22694, P17252, P62873, P63218, P50151, P15104

GRIA4, GRIN2D, PRKACB, PRKCA, GNB1, GNG5, GNG10, GLUL

Miconazole

hsa04725

Cholinergic synapse

2.92E-02

P62873, P63218, P50151, P42338

GNB1, GNG5, GNG10, PIK3CB

Miconazole

hsa04726

Serotonergic synapse

2.62E-02

P22694, P17252, P31645

PRKACB, PRKCA, SLC6A4

Miconazole

hsa04727

GABAergic synapse

5.76E-05

P62873, P63218, P50151, P15104

GNB1, GNG5, GNG10, GLUL

Miconazole

hsa04730

Long-term depression

4.53E-03

Q14344, P07948

GNA13, LYN

Miconazole

hsa04744

Phototransduction

1.32E-02

P62873, P0DP23

GNB1, CALM1

Miconazole

hsa04750

Inflammatory mediator regulation of TRP channels

3.91E-03

P14778, P19174, P42338, P24723, P0DP23

IL1R1, PLCG1, PIK3CB, PRKCH, CALM1

Miconazole

hsa04810

Regulation of actin cytoskeleton

2.61E-02

P12814, Q13009, P42338, P11215, Q14344, Q9NRA1

ACTN1, TIAM1, PIK3CB, ITGAM, GNA13, PDGFC

Miconazole

hsa04910

Insulin signaling pathway

2.35E-02

P22694, P06737, P49841

PRKACB, PYGL, GSK3B

Miconazole

hsa04911

Insulin secretion

3.01E-02

P22694, P17252

PRKACB, PRKCA

Miconazole

hsa04913

Ovarian steroidogenesis

1.28E-02

P42330, P22694

AKR1C3, PRKACB

Miconazole

hsa04914

Progesterone-mediated oocyte maturation

4.29E-03

Q17RY0, P42338, Q13370, P30304, P08238, P51812, Q02750

CPEB4, PIK3CB, PDE3B, CDC25A, HSP90AB1, RPS6KA3, MAP2K1

Miconazole

hsa04918

Thyroid hormone synthesis

3.01E-02

P22694, P17252

PRKACB, PRKCA

Miconazole

hsa04919

Thyroid hormone signaling pathway

7.11E-03

P49841, P22694, O60244, Q9NVC6

GSK3B, PRKACB, MED14, MED17

Miconazole

hsa04920

Adipocytokine signaling pathway

4.31E-02

Q9Y478, Q96RR4

PRKAB1, CAMKK2

Miconazole

hsa04925

Aldosterone synthesis and secretion

9.86E-03

P17252, P22694, P20020

PRKCA, PRKACB, ATP2B1

Miconazole

hsa04926

Relaxin signaling pathway

8.74E-03

P25963, P42338, P62873, P63218, P50151, P49767

NFKBIA, PIK3CB, GNB1, GNG5, GNG10, VEGFC

Miconazole

hsa04929

GnRH secretion

3.63E-02

P42338, P49407

PIK3CB, ARRB1

Miconazole

hsa04931

Insulin resistance

1.94E-02

P01375, P49841, P06737

TNF, GSK3B, PYGL

Miconazole

hsa04933

AGE-RAGE signaling pathway in diabetic complications

1.25E-02

P84022, Q13485, P10415

SMAD3, SMAD4, BCL2

Miconazole

hsa04960

Aldosterone-regulated sodium reabsorption

4.38E-02

P48048

KCNJ1

Miconazole

hsa04961

Endocrine and other factor-regulated calcium reabsorption

9.85E-05

P20020, P17252, P22694

ATP2B1, PRKCA, PRKACB

Miconazole

hsa04962

Vasopressin-regulated water reabsorption

6.61E-03

P22694, Q13561

PRKACB, DCTN2

Miconazole

hsa04970

Salivary secretion

7.14E-03

P22694, P20020, P17252

PRKACB, ATP2B1, PRKCA

Miconazole

hsa04972

Pancreatic secretion

1.48E-03

P20020, P17252

ATP2B1, PRKCA

Miconazole

hsa04973

Carbohydrate digestion and absorption

4.12E-03

O43451, P42338

MGAM, PIK3CB

Miconazole

hsa04975

Fat digestion and absorption

3.43E-02

O14494

PLPP1

Miconazole

hsa04976

Bile secretion

1.51E-03

P22694, P08183

PRKACB, ABCB1

Miconazole

hsa05010

Alzheimer disease

9.24E-04

O15239, P13073, O15399, Q9NZJ5, Q13564, P18848, Q71U36, O15169, P67870, P09603, P05141, P12236, P21796, P28070, P43686

NDUFA1, COX4I1, GRIN2D, EIF2AK3, APPBP1, ATF4, TUBA1A, AXIN1, CSNK2B, CSF1, SLC25A5, SLC25A6, VDAC1, PSMB4, PSMC4

Miconazole

hsa05012

Parkinson disease

3.44E-03

O15239, P13073, P05141, P12236, P21796, P60604, P18848, P28070, P43686, P19174, P0DP23, Q71U36, Q13509

NDUFA1, COX4I1, SLC25A5, SLC25A6, VDAC1, UBE2G2, ATF4, PSMB4, PSMC4, PLCG1, CALM1, TUBA1A, TUBB3

Miconazole

hsa05016

Huntington disease

2.46E-05

Q9GZM3, P52435, Q9NYC9

POLR2J2, POLR2J, DNAH9

Miconazole

hsa05017

Spinocerebellar ataxia

4.66E-02

P28070, P43686, P05141, P12236

PSMB4, PSMC4, SLC25A5, SLC25A6

Miconazole

hsa05020

Prion disease

1.55E-03

P46531, O15239, P13073, P18848, P05141, P12236, P28070, P43686, P67870, P51636

NOTCH1, NDUFA1, COX4I1, ATF4, SLC25A5, SLC25A6, PSMB4, PSMC4, CSNK2B, CAV2

Miconazole

hsa05022

Pathways of neurodegeneration - multiple diseases

5.20E-04

P67870, O15239, Q16718, P13073, P18848, Q13561, P48058, P05141, P12236, P17252, P20333, O15169, Q08752, P28070, P43686

CSNK2B, NDUFA1, NDUFA5, COX4I1, ATF4, DCTN2, GRIA4, SLC25A5, SLC25A6, PRKCA, TNFRSF1B, AXIN1, PPID, PSMB4, PSMC4

Miconazole

hsa05031

Amphetamine addiction

1.69E-02

P48058, P22694, P17252

GRIA4, PRKACB, PRKCA

Miconazole

hsa05032

Morphine addiction

2.74E-04

P62873, P63218, P50151, Q13370, Q07343, P43250

GNB1, GNG5, GNG10, PDE3B, PDE4B, GRK6

Miconazole

hsa05034

Alcoholism

9.92E-05

Q13547, P0DP23, P62873, P63218, P50151, Q93077, P62807, Q93079, O60814, P68431

HDAC1, CALM1, GNB1, GNG5, GNG10, HIST1H2AC, HIST1H2BC, H2BC9, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12

Miconazole

hsa05100

Bacterial invasion of epithelial cells

4.50E-02

Q92529

SHC3

Miconazole

hsa05110

Vibrio cholerae infection

3.01E-02

P17252, P22694

PRKCA, PRKACB

Miconazole

hsa05120

Epithelial cell signaling in Helicobacter pylori infection

2.27E-02

Q16539, P09341, P25024, P25025

MAPK14, CXCL1, CXCR1, CXCR2

Miconazole

hsa05132

Salmonella infection

2.07E-03

P25963, P08238, P01106, P42338, Q13489, P10415, O75369, Q9BQS8, Q71U36, Q13509, P49754

NFKBIA, HSP90AB1, MYC, PIK3CB, BIRC3, BCL2, FLNB, FYCO1, TUBA1A, TUBB3, VPS41

Miconazole

hsa05140

Leishmaniasis

2.47E-02

P13612, O75015, P01375, P49006, Q16539

ITGA4, FCGR3B, TNF, MARCKSL1, MAPK14

Miconazole

hsa05144

Malaria

1.44E-02

P60033, O60603, P35443, P26718

CD81, TLR2, THBS4, KLRK1

Miconazole

hsa05145

Toxoplasmosis

2.78E-02

P25963, P10415, Q13489

NFKBIA, BCL2, BIRC3

Miconazole

hsa05146

Amoebiasis

4.20E-02

P09341, P14778, P27930, P01375, P05089

CXCL1, IL1R1, IL1R2, TNF, ARG1

Miconazole

hsa05150

Staphylococcus aureus infection

2.36E-03

P0C0L4, P13646, Q14532, P59665, P59666, P49913

C4A, KRT13, KRT32, DEFA1; DEFA1B, DEFA3, CAMP

Miconazole

hsa05161

Hepatitis B

8.49E-03

P25963, Q13485, P10415, P84022

NFKBIA, SMAD4, BCL2, SMAD3

Miconazole

hsa05162

Measles

1.84E-02

P01568, P25963, P42224, P14784, P07766, P42338, P11142

IFNA21, NFKBIA, STAT1, IL2RB, CD3E, PIK3CB, HSPA8

Miconazole

hsa05163

Human cytomegalovirus infection

6.94E-05

P42338, P01375, P25963, P62873, P63218, P50151, P0DP23, Q14344, P49841, P01106, P14778, P25025, Q16539, O00463, P30101, P01568

PIK3CB, TNF, NFKBIA, GNB1, GNG5, GNG10, CALM1, GNA13, GSK3B, MYC, IL1R1, CXCR2, MAPK14, TRAF5, PDIA3, IFNA21

Miconazole

hsa05167

Kaposi sarcoma-associated herpesvirus infection

4.21E-06

P01568, P42224, P25963, P42338, P62873, P62879, P63218, P50151, P19174, P16298, Q02750, P07948, P01106, P0DP23, P0CG47

IFNA21, STAT1, NFKBIA, PIK3CB, GNB1, GNB2, GNG5, GNG10, PLCG1, PPP3CB, MAP2K1, LYN, MYC, CALM1, UBB

Miconazole

hsa05168

Herpes simplex virus 1 infection

6.60E-03

P25963, P01568, P42224, Q07955, Q01130, Q13243, P30101, P42338, Q9Y2A4, Q13398, P51522, P17038, P52738, O75820

NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, PDIA3, PIK3CB, ZNF443, ZNF211, ZNF83, ZNF43, ZNF140, ZNF189

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P25963	NFKBIA	NF-kappa-B inhibitor alpha	0.711
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	P25963	NFKBIA	NF-kappa-B inhibitor alpha	-0.825
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P01568	IFNA21	Interferon alpha-21	-0.701
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.838
P40925	MDH1	Malate dehydrogenase, cytoplasmic	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	0.866
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Q07955	SFRS1	Serine/arginine-rich splicing factor 1	-0.703
P40925	MDH1	Malate dehydrogenase, cytoplasmic	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	0.835
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Q01130	SFRS2	Serine/arginine-rich splicing factor 2	-0.781
P40925	MDH1	Malate dehydrogenase, cytoplasmic	Q13243	SFRS5	Serine/arginine-rich splicing factor 5	0.908
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P30101	PDIA3	Protein disulfide-isomerase A3	0.896
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	-0.805
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Q9Y2A4	ZNF443	Zinc finger protein 443	0.731
P40925	MDH1	Malate dehydrogenase, cytoplasmic	Q13398	ZNF211	Zinc finger protein 211	0.891
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	P51522	ZNF83	Zinc finger protein 83	0.851
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	P17038	ZNF43	Zinc finger protein 43	0.718
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	P52738	ZNF140	Zinc finger protein 140	0.71
P40925	MDH1	Malate dehydrogenase, cytoplasmic	O75820	ZNF189	Zinc finger protein 189	-0.749
Q13627	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	O75820	ZNF189	Zinc finger protein 189	0.768

Miconazole

hsa05169

Epstein-Barr virus infection

2.24E-04

P13765, P01106, Q13547, O00463, P25963, Q16539, P42338, P07948, P30101, Q13761, P24522, O75293, P42224, P01568, O60603, P07766, P09693, P20963

HLA-DOB, MYC, HDAC1, TRAF5, NFKBIA, MAPK14, PIK3CB, LYN, PDIA3, RUNX3, GADD45A, GADD45B, STAT1, IFNA21, TLR2, CD3E, CD3G, CD247

Genes in community(ComG)	Gene name of ComG	Protein name of ComG	Co-expressed genes in pathway (PathG)	Gene name of PathG	Protein name of PathG	Coexpression
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P13765	HLA-DOB	HLA class II histocompatibility antigen, DO beta chain	-0.731
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P01106	MYC	Myc proto-oncogene protein	0.719
P40925	MDH1	Malate dehydrogenase, cytoplasmic	Q13547	HDAC1	Histone deacetylase 1	0.701
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	Q13547	HDAC1	Histone deacetylase 1	-0.727
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	O00463	TRAF5	TNF receptor-associated factor 5	-0.788
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P25963	NFKBIA	NF-kappa-B inhibitor alpha	0.711
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	Q16539	MAPK14	Mitogen-activated protein kinase 14	0.901
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P42338	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	-0.805
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P07948	LYN	Tyrosine-protein kinase Lyn	-0.852
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P30101	PDIA3	Protein disulfide-isomerase A3	0.896
P40925	MDH1	Malate dehydrogenase, cytoplasmic	Q13761	RUNX3	Runt-related transcription factor 3	0.804
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P24522	GADD45A	Growth arrest and DNA damage-inducible protein GADD45 alpha	0.796
P40925	MDH1	Malate dehydrogenase, cytoplasmic	O75293	GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta	-0.847
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P42224	STAT1	Signal transducer and activator of transcription 1-alpha/beta	0.838
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P01568	IFNA21	Interferon alpha-21	-0.701
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	O60603	TLR2	Toll-like receptor 2	0.72
P40925	MDH1	Malate dehydrogenase, cytoplasmic	P07766	CD3E	T-cell surface glycoprotein CD3 epsilon chain	0.839
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P09693	CD3G	T-cell surface glycoprotein CD3 gamma chain	-0.734
P05186	ALPL	Alkaline phosphatase, tissue-nonspecific isozyme	P20963	CD247	T-cell surface glycoprotein CD3 zeta chain	-0.703

Miconazole

hsa05170

Human immunodeficiency virus 1 infection

5.72E-05

P42338, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, Q05397, P30101, P01568, P25963, P19174, P07766, P20333

PIK3CB, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, PTK2, PDIA3, IFNA21, NFKBIA, PLCG1, CD3E, TNFRSF1B

Miconazole

hsa05171

Coronavirus disease - COVID-19

1.08E-04

P23396, P62753, P62249, P42677, P40429, P36578, Q02878, P62917, P32969, Q07020, P46776, P62910, P05386

RPS3, RPS6, RPS16, RPS27, RPL13A, RPL4, RPL6, RPL8, RPL9, RPL18, RPL27A, RPL32, RPLP1

Miconazole

hsa05200

Pathways in cancer

1.82E-03

P42338, P08238, P42224, P25963, P19174, P01106, P43246, Q13547, P49767, P62873, P63218, P50151, Q14344, O75293, P0DP23, P01568, P14784

PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, MSH2, HDAC1, VEGFC, GNB1, GNG5, GNG10, GNA13, GADD45B, CALM1, IFNA21, IL2RB

Miconazole

hsa05203

Viral carcinogenesis

6.72E-04

P42338, P06746, P07948, P29083, Q13547, Q15283, P12814, P25963, P62807, Q93079, O60814

PIK3CB, POLB, LYN, GTF2E1, HDAC1, RASA2, ACTN1, NFKBIA, HIST1H2BC, H2BC9, H2BC12

Miconazole

hsa05204

Chemical carcinogenesis

1.48E-02

P78417, P11712

GSTO1, CYP2C9

Miconazole

hsa05206

MicroRNAs in cancer

2.79E-02

P30304, P09493, P01106, P42338, Q13547, P20827, P19174

CDC25A, TPM1, MYC, PIK3CB, HDAC1, EFNA1, PLCG1

Miconazole

hsa05210

Colorectal cancer

1.78E-02

P84022, Q13485, P10415

SMAD3, SMAD4, BCL2

Miconazole

hsa05212

Pancreatic cancer

3.52E-02

P84022, Q13485

SMAD3, SMAD4

Miconazole

hsa05213

Endometrial cancer

3.79E-02

O15169, Q02750

AXIN1, MAP2K1

Miconazole

hsa05214

Glioma

1.28E-03

P09619, P0DP23, Q02750, P42338, P19174, O75293

PDGFRB, CALM1, MAP2K1, PIK3CB, PLCG1, GADD45B

Miconazole

hsa05218

Melanoma

7.97E-04

P09619, Q9NRA1, P42338, Q02750, O75293

PDGFRB, PDGFC, PIK3CB, MAP2K1, GADD45B

Miconazole

hsa05220

Chronic myeloid leukemia

1.14E-03

Q13547, P01106, Q13485, P25963, P84022, P42338, O75293

HDAC1, MYC, SMAD4, NFKBIA, SMAD3, PIK3CB, GADD45B

Miconazole

hsa05222

Small cell lung cancer

1.50E-02

Q13489, P10415, P25963

BIRC3, BCL2, NFKBIA

Miconazole

hsa05224

Breast cancer

3.88E-02

P46531, Q9UM47, O15169

NOTCH1, NOTCH3, AXIN1

Miconazole

hsa05225

Hepatocellular carcinoma

1.85E-02

Q92529, P51531

SHC3, SMARCA2

Miconazole

hsa05226

Gastric cancer

4.33E-03

Q02750, O15169, P84022, Q13485, P10415

MAP2K1, AXIN1, SMAD3, SMAD4, BCL2

Miconazole

hsa05230

Central carbon metabolism in cancer

4.10E-02

P09619, Q02750

PDGFRB, MAP2K1

Miconazole

hsa05231

Choline metabolism in cancer

2.92E-03

P42338, Q9NRA1, Q9Y259, P19174, P23743

PIK3CB, PDGFC, CHKB, PLCG1, DGKA

Miconazole

hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

3.94E-03

P25963, P42338, P19174, P07766, P20963, P09693, P06239, P42224, O60603, Q16539

NFKBIA, PIK3CB, PLCG1, CD3E, CD247, CD3G, LCK, STAT1, TLR2, MAPK14

Miconazole

hsa05322

Systemic lupus erythematosus

1.31E-04

P09871, Q93077, P62807, O60814, P68431

C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12

Miconazole

hsa05415

Diabetic cardiomyopathy

2.75E-02

P17252, P14598, Q15080, Q16718

PRKCA, NCF1, NCF4, NDUFA5

Miconazole

hsa05418

Fluid shear stress and atherosclerosis

2.43E-03

Q16539, P42338, P10599, P14780, P01375, P14778, P27930

MAPK14, PIK3CB, TXN, MMP9, TNF, IL1R1, IL1R2

Community members of Miconazole (S_DC: 3.63)

UniProtAC

Gene Name

Protein Name

Reported/
Predicted

S_PV

NR1I2

Nuclear receptor subfamily 1 group I member 2

Reported

0.0315

0.9493

1.9143

P16389

KCNA2

Potassium voltageNonegated channel subfamily A member 2

Reported

0.0131

0.0835

0.1736

P22001

KCNA3

Potassium voltageNonegated channel subfamily A member 3

Reported

0.1396

0.5055

1.0809

P17658

KCNA6

Potassium voltageNonegated channel subfamily A member 6

Reported

0.2827

0.0785

0.2984

O95259

KCNH1

Potassium voltageNonegated channel subfamily H member 1

Reported

0.0425

0.0465

0.1143

P54284

CACNB3

VoltageNonedependent LNonetype calcium channel subunit betaNone3

Reported

0.1026

0.1539

0.3291

0.6881

P11712

CYP2C9

Cytochrome P450 2C9

Predicted

0.0106

0.1524

2.1577

P05186

ALPL

Alkaline phosphatase, tissueNonenonspecific isozyme

Predicted

0.3064

0.4143

0.1992

1.181

P40925

MDH1

Malate dehydrogenase, cytoplasmic

Predicted

0.3566

0.2746

0.2426

0.97

P08183

ABCB1

ATPNonedependent translocase ABCB1

Predicted

0.0788

0.2052

2.2446

P11511

CYP19A1

Aromatase

Predicted

0.8156

0.1588

2.5666

P61088

UBE2N

UbiquitinNoneconjugating enzyme E2 N

Predicted

0.1102

0.3825

0.3736

1.1937

Q13627

DYRK1A

Dual specificity tyrosineNonephosphorylationNoneregulated kinase 1A

Predicted

0.015

0.7082

1.4239

Q9ULS6

KCNS2

Potassium voltageNonegated channel subfamily S member 2

Predicted

0.1955

0.0412

0.1801

P48048

KCNJ1

ATPNonesensitive inward rectifier potassium channel 1

Predicted

0.0042

0.282

0.1274

0.6935

Q99712

KCNJ15

ATPNonesensitive inward rectifier potassium channel 15

Predicted

0.1587

0.0779

0.1267

0.3619

P78508

KCNJ10

ATPNonesensitive inward rectifier potassium channel 10

Predicted

0.0731

0.0878

0.2067

0.4189

P10826

RARB

Retinoic acid receptor beta

Predicted

0.0094

0.3466

0.3005

0.9983

PharmaCoNets of Miconazole (SPCN: 64.96 )

Miconazole regulated-network (SDN: 17.90)

Community members of Miconazole (SDC: 3.63)

PharmaCoNets of Miconazole (S_PCN: 64.96 )

Miconazole regulated-network (S_DN: 17.90)

Community members of Miconazole (S_DC: 3.63)