PharmaCoNets of Metocurine-iodide (SPCN: 9.69 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Metocurine-iodidehsa00220Arginine biosynthesis4.88E-021P49448GLUD2More
Metocurine-iodidehsa00250Alanine, aspartate and glutamate metabolism4.88E-021P49448GLUD2More
Metocurine-iodidehsa00471D-Glutamine and D-glutamate metabolism1.65E-021P49448GLUD2More
Metocurine-iodidehsa00910Nitrogen metabolism4.88E-021P49448GLUD2More
Metocurine-iodidehsa01522Endocrine resistance4.96E-023Q16539, P04637, P10415MAPK14, TP53, BCL2More
Metocurine-iodidehsa03008Ribosome biogenesis in eukaryotes1.56E-023Q9NYH9, P78345, O15381UTP6, RPP38, NVLMore
Metocurine-iodidehsa03060Protein export3.28E-021Q15070OXA1LMore
Metocurine-iodidehsa04061Viral protein interaction with cytokine and cytokine receptor1.12E-0310P51684, P32248, P09341, P19875, P25024, P02775, P25025, P47992, Q9UBD3, P14784CCR6, CCR7, CXCL1, CXCL2, CXCR1, PPBP, CXCR2, XCL1, XCL2, IL2RBMore
Metocurine-iodidehsa04062Chemokine signaling pathway1.83E-028P25024, P25025, P09341, P19875, P42338, P19174, P63218, P50151CXCR1, CXCR2, CXCL1, CXCL2, PIK3CB, PLCG1, GNG5, GNG10More
Metocurine-iodidehsa04064NF-kappa B signaling pathway2.15E-027P14778, P19174, Q04759, P06239, P09341, P19875, Q06643IL1R1, PLCG1, PRKCQ, LCK, CXCL1, CXCL2, LTBMore
Metocurine-iodidehsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Metocurine-iodidehsa04152AMPK signaling pathway2.34E-022Q96EB6, P36956SIRT1, SREBF1More
Metocurine-iodidehsa04210Apoptosis1.68E-026P04637, P10415, P24522, Q13077, P43234, Q14643TP53, BCL2, GADD45A, TRAF1, CTSO, ITPR1More
Metocurine-iodidehsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Metocurine-iodidehsa04640Hematopoietic cell lineage1.37E-027P14778, P27930, P11215, P25063, P07766, P01732, P09564IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD7More
Metocurine-iodidehsa04650Natural killer cell mediated cytotoxicity2.48E-038P19174, P06239, O60880, P20963, P42338, Q13241, P26718, O14931PLCG1, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3More
Metocurine-iodidehsa04658Th1 and Th2 cell differentiation2.55E-0512Q04759, P07766, P20963, P09693, Q16539, P19174, P06239, P23771, Q9UL17, P14784, P13765, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, LCK, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Metocurine-iodidehsa04659Th17 cell differentiation1.25E-038Q04759, P19174, P06239, P14784, P14778, Q9UL17, P07766, P20963PRKCQ, PLCG1, LCK, IL2RB, IL1R1, TBX21, CD3E, CD247More
Metocurine-iodidehsa04660T cell receptor signaling pathway3.37E-038Q04759, P42338, P19174, P07766, P20963, P01732, Q13191, P06239PRKCQ, PIK3CB, PLCG1, CD3E, CD247, CD8A, CBLB, LCKMore
Metocurine-iodidehsa04722Neurotrophin signaling pathway2.34E-024Q16566, P04637, Q16539, P10415CAMK4, TP53, MAPK14, BCL2More
Metocurine-iodidehsa04725Cholinergic synapse3.92E-023Q14643, Q16566, P10415ITPR1, CAMK4, BCL2More
Metocurine-iodidehsa04750Inflammatory mediator regulation of TRP channels7.24E-035P14778, P19174, P42338, P24723, Q04759IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQMore
Metocurine-iodidehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Metocurine-iodidehsa04964Proximal tubule bicarbonate reclamation4.88E-021P49448GLUD2More
Metocurine-iodidehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Metocurine-iodidehsa05120Epithelial cell signaling in Helicobacter pylori infection2.78E-035P09341, P19875, P19174, P25024, P25025CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Metocurine-iodidehsa05134Legionellosis1.29E-024P11215, P11142, P09341, P19875ITGAM, HSPA8, CXCL1, CXCL2More
Metocurine-iodidehsa05146Amoebiasis2.21E-048P09341, P19875, P14778, P27930, P42338, P11215, P05089, P12814CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, ACTN1More
Metocurine-iodidehsa05169Epstein-Barr virus infection3.45E-026P13765, P04637, P10415, Q16539, P24522, P09693HLA-DOB, TP53, BCL2, MAPK14, GADD45A, CD3GMore
Metocurine-iodidehsa05202Transcriptional misregulation in cancer2.62E-027Q15532, P14923, Q13077, O15550, P04637, P05164, P24522SS18, JUP, TRAF1, UTX, TP53, MPO, GADD45AMore
Metocurine-iodidehsa05210Colorectal cancer2.89E-024P10415, P04637, Q9UJU2, P24522BCL2, TP53, LEF1, GADD45AMore
Metocurine-iodidehsa05213Endometrial cancer2.21E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Metocurine-iodidehsa05214Glioma2.21E-023Q16566, P04637, P24522CAMK4, TP53, GADD45AMore
Metocurine-iodidehsa05216Thyroid cancer6.17E-033Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Metocurine-iodidehsa05217Basal cell carcinoma1.56E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Metocurine-iodidehsa05221Acute myeloid leukemia3.00E-023P14923, Q9UJU2, P05164JUP, LEF1, MPOMore
Metocurine-iodidehsa05222Small cell lung cancer2.34E-024P10415, Q13077, P04637, P24522BCL2, TRAF1, TP53, GADD45AMore
Metocurine-iodidehsa05224Breast cancer4.96E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Metocurine-iodidehsa05226Gastric cancer1.12E-025Q9UJU2, P04637, P24522, P14923, P10415LEF1, TP53, GADD45A, JUP, BCL2More
Metocurine-iodidehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer8.27E-036P42338, P19174, P07766, P20963, P06239, Q04759PIK3CB, PLCG1, CD3E, CD247, LCK, PRKCQMore

Community members of Metocurine-iodide (SDC: 1.90)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)