PharmaCoNets of Methohexital (SPCN: 0.86 )

Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Methohexitalhsa00380Tryptophan metabolism4.14E-021Q16613AANATMore
Methohexitalhsa03050Proteasome1.40E-021P55036PSMD4More
Methohexitalhsa04120Ubiquitin mediated proteolysis6.89E-035Q14145, Q13042, Q13191, Q15751, Q7Z6Z7KEAP1, CDC16, CBLB, HERC1, HUWE1More
Methohexitalhsa04621NOD-like receptor signaling pathway4.31E-024P01375, P59665, P59666, P12838TNF, DEFA1; DEFA1B, DEFA3, DEFA4More
Methohexitalhsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Methohexitalhsa05032Morphine addiction1.09E-022P78334, P32298GABRE, GRK4More
Methohexitalhsa05142Chagas disease2.26E-023P01375, P30679, P48023TNF, GNA15, FASLGMore
Methohexitalhsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Methohexitalhsa05150Staphylococcus aureus infection1.83E-023P59665, P59666, P12838DEFA1; DEFA1B, DEFA3, DEFA4More
Methohexitalhsa05171Coronavirus disease - COVID-194.47E-022Q9UHA3, O14786RSL24D1, NRP1More
Methohexitalhsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Methohexitalhsa05332Graft-versus-host disease3.70E-022P48023, P01375FASLG, TNFMore

Community members of Methohexital (SDC: 0.51)

UniProtACGene NameProtein NameReported/
Predicted
DisGeNETSPVSdrugabilitySHiSBiNSDisG
P78334GABREGammaNoneaminobutyric acid receptor subunit epsilonPredicted00.13940.40970.15791.0469
P28472GABRB3GammaNoneaminobutyric acid receptor subunit betaNone3Predicted00.15590.43870.16951.1248
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)