| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
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| Mercaptopurine | hsa00030 | Pentose phosphate pathway | 1.95E-02 | 3 | P51854, P08237, P37837 | TKTL1, PFKM, TALDO1 | More | | | Mercaptopurine | hsa01100 | Metabolic pathways | 1.03E-02 | 28 | Q9Y234, P35790, Q16772, P15144, P30041, O14732, Q02153, Q16774, P20839, P00918, P10768, P55809, P06280, Q9Y6K0, P08237, P21399, Q9UHK6, P51854, Q86VZ5, Q9BVK2, P15907, O96024, P37837, P50213, P43490, Q969G6, Q13029, Q9NVH6 | LIPT1, CHKA, GSTA3, ANPEP, PRDX6, IMPA2, GUCY1B3, GUK1, IMPDH1, CA2, ESD, OXCT1, GLA, CEPT1, PFKM, ACO1, AMACR, TKTL1, SGMS1, ALG8, ST6GAL1, B3GALT4, TALDO1, IDH3A, PBEF1, RFK, PRDM2, TMLHE | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
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| P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q9Y234 | LIPT1 | Lipoyltransferase 1, mitochondrial | 0.778 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P35790 | CHKA | Choline kinase alpha | -0.856 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q16772 | GSTA3 | Glutathione S-transferase A3 | -0.768 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P15144 | ANPEP | Aminopeptidase N | 0.846 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P30041 | PRDX6 | Peroxiredoxin-6 | 0.785 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | O14732 | IMPA2 | Inositol monophosphatase 2 | 0.738 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q02153 | GUCY1B3 | Guanylate cyclase soluble subunit beta-1 | -0.774 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q16774 | GUK1 | Guanylate kinase | 0.757 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | 1 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P00918 | CA2 | Carbonic anhydrase 2 | 0.772 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P10768 | ESD | S-formylglutathione hydrolase | -0.701 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P55809 | OXCT1 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | -0.744 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P06280 | GLA | Alpha-galactosidase A | 0.728 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q9Y6K0 | CEPT1 | Choline/ethanolaminephosphotransferase 1 | 0.771 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P08237 | PFKM | ATP-dependent 6-phosphofructokinase, muscle type | 0.868 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P21399 | ACO1 | Cytoplasmic aconitate hydratase | -0.739 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q9UHK6 | AMACR | Alpha-methylacyl-CoA racemase | -0.784 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P51854 | TKTL1 | Transketolase-like protein 1 | -0.753 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q86VZ5 | SGMS1 | Phosphatidylcholine:ceramide cholinephosphotransferase 1 | -0.81 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q9BVK2 | ALG8 | Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase | -0.726 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P15907 | ST6GAL1 | Beta-galactoside alpha-2,6-sialyltransferase 1 | -0.827 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | O96024 | B3GALT4 | Beta-1,3-galactosyltransferase 4 | 0.797 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P37837 | TALDO1 | Transaldolase | 0.732 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P50213 | IDH3A | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | -0.732 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | P43490 | PBEF1 | Nicotinamide phosphoribosyltransferase | 0.702 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q969G6 | RFK | Riboflavin kinase | 0.705 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q13029 | PRDM2 | PR domain zinc finger protein 2 | 0.744 | | P20839 | IMPDH1 | Inosine-5'-monophosphate dehydrogenase 1 | Q9NVH6 | TMLHE | Trimethyllysine dioxygenase, mitochondrial | -0.721 |
| | Mercaptopurine | hsa01200 | Carbon metabolism | 1.81E-02 | 6 | P51854, P08237, P37837, P50213, P21399, P10768 | TKTL1, PFKM, TALDO1, IDH3A, ACO1, ESD | More | | | Mercaptopurine | hsa01210 | 2-Oxocarboxylic acid metabolism | 1.73E-02 | 2 | P21399, P50213 | ACO1, IDH3A | More | | | Mercaptopurine | hsa01230 | Biosynthesis of amino acids | 7.71E-03 | 5 | P08237, P51854, P21399, P50213, P37837 | PFKM, TKTL1, ACO1, IDH3A, TALDO1 | More | | | Mercaptopurine | hsa04330 | Notch signaling pathway | 3.28E-03 | 4 | Q92542, P49768, Q92830, P78504 | NCSTN, PSEN1, KAT2A, JAG1 | More | | | Mercaptopurine | hsa04610 | Complement and coagulation cascades | 2.46E-02 | 3 | P00734, P0C0L4, P21730 | F2, C4A, C5AR1 | More | | | Mercaptopurine | hsa05144 | Malaria | 3.09E-02 | 4 | P69905, P68871, O60603, P10145 | HBA2, HBB, TLR2, IL8 | More | | | Mercaptopurine | hsa05150 | Staphylococcus aureus infection | 4.66E-02 | 4 | P0C0L4, P21730, P21462, P13646 | C4A, C5AR1, FPR1, KRT13 | More | |
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