PharmaCoNets of Mefenamic-acid (SPCN: 140.88 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Mefenamic-acidhsa00030Pentose phosphate pathway1.69E-022P60891, P37837PRPS1, TALDO1More
Mefenamic-acidhsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Mefenamic-acidhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Mefenamic-acidhsa00190Oxidative phosphorylation1.39E-034Q16718, Q13488, P36542, O14521NDUFA5, TCIRG1, ATP5C1, SDHDMore
Mefenamic-acidhsa00480Glutathione metabolism3.29E-044Q9UJ14, Q16772, P09211, P30041GGTL3, GSTA3, GSTP1, PRDX6More
Mefenamic-acidhsa00500Starch and sucrose metabolism6.17E-033O43451, P46976, P06737MGAM, GYG1, PYGLMore
Mefenamic-acidhsa00510N-Glycan biosynthesis1.00E-022O94777, Q9BVK2DPM2, ALG8More
Mefenamic-acidhsa00561Glycerolipid metabolism3.09E-022P14550, Q86XP1AKR1A1, DGKHMore
Mefenamic-acidhsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis3.47E-032O94777, Q14442DPM2, PIGHMore
Mefenamic-acidhsa00565Ether lipid metabolism1.61E-042Q9Y6K0, Q8N661CEPT1, TMEM86BMore
Mefenamic-acidhsa00600Sphingolipid metabolism4.47E-022Q96G23, Q86VZ5LASS2, SGMS1More
Mefenamic-acidhsa00630Glyoxylate and dicarboxylate metabolism1.62E-053P40925, P40926, P15104MDH1, MDH2, GLULMore
Mefenamic-acidhsa00730Thiamine metabolism2.27E-022P05186, P24666ALPL, ACP1More
Mefenamic-acidhsa00860Porphyrin and chlorophyll metabolism1.69E-022P36551, P30043CPOX, BLVRBMore
Mefenamic-acidhsa00980Metabolism of xenobiotics by cytochrome P4505.46E-032Q16772, P09211GSTA3, GSTP1More
Mefenamic-acidhsa00982Drug metabolism - cytochrome P4501.06E-022Q16772, P09211GSTA3, GSTP1More
Mefenamic-acidhsa00983Drug metabolism - other enzymes1.73E-045P04183, P32320, P05164, Q16772, P09211TK1, CDA, MPO, GSTA3, GSTP1More
Mefenamic-acidhsa01100Metabolic pathways2.14E-0524Q9Y234, P35790, Q16772, P09211, Q9UJ14, P30041, Q6ZQY3, P20839, P40926, O94777, Q7KZN9, Q9Y6K0, P15121, Q86XP1, P14550, Q9UHK6, Q86VZ5, Q96G23, Q9BVK2, Q14442, Q9BQB6, Q06055, Q99437, Q9NVH6LIPT1, CHKA, GSTA3, GSTP1, GGTL3, PRDX6, GADL1, IMPDH1, MDH2, DPM2, COX15, CEPT1, AKR1B1, DGKH, AKR1A1, AMACR, SGMS1, LASS2, ALG8, PIGH, VKORC1, ATP5G2, ATP6V0B, TMLHEMore
Mefenamic-acidhsa01230Biosynthesis of amino acids3.59E-023P60891, Q99707, P37837PRPS1, MTR, TALDO1More
Mefenamic-acidhsa01524Platinum drug resistance4.44E-022Q16772, P09211GSTA3, GSTP1More
Mefenamic-acidhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Mefenamic-acidhsa03008Ribosome biogenesis in eukaryotes6.93E-046Q9NYH9, O14980, O60832, P78345, Q9BVP2, Q9GZY0UTP6, XPO1, DKC1, RPP38, GNL3, NXF2; NXF2BMore
Mefenamic-acidhsa03010Ribosome1.88E-026P62753, P25398, P32969, P62829, P18077, P36578RPS6, RPS12, RPL9, RPL23, RPL35A, RPL4More
Mefenamic-acidhsa03013RNA transport3.37E-0919O14980, P52298, Q09161, O14893, P61326, Q9GZY0, Q7Z3B4, P35658, P47813, Q14152, O75822, P78345, Q14240, Q9BZI7, P23588, Q9Y6A5, Q06787, P51114, Q53GS7XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NXF2; NXF2B, NUP54, NUP214, EIF1AX, EIF3A, EIF3J, RPP38, EIF4A2, UPF3B, EIF4B, TACC3, FMR1, FXR1, GLE1More
Mefenamic-acidhsa03015mRNA surveillance pathway9.78E-036O43148, Q16537, P61326, Q9GZY0, P52298, Q53GS7RNMT, PPP2R5E, MAGOH, NXF2; NXF2B, NCBP2, GLE1More
Mefenamic-acidhsa03020RNA polymerase3.59E-022P30876, P62487POLR2B, POLR2GMore
Mefenamic-acidhsa03022Basal transcription factors3.50E-023P20226, O00268, Q15544TBP, TAF4, TAF11More
Mefenamic-acidhsa03040Spliceosome3.87E-0713Q14562, O43143, O60508, P17844, P08579, P51991, P61978, Q07955, Q01130, Q13243, P11142, O43447, O75643DHX8, DHX15, CDC40, DDX5, SNRPB2, HNRPA3, HNRPK, SFRS1, SFRS2, SFRS5, HSPA8, PPIH, ASCC3L1More
Mefenamic-acidhsa04012ErbB signaling pathway1.34E-024P16333, P19174, P42338, P01106NCK1, PLCG1, PIK3CB, MYCMore
Mefenamic-acidhsa04014Ras signaling pathway2.92E-0410P42338, P20827, Q9NRA1, P49767, Q13009, P0DP23, P62873, P63218, P50151, P19174PIK3CB, EFNA1, PDGFC, VEGFC, TIAM1, CALM1, GNB1, GNG5, GNG10, PLCG1More
Mefenamic-acidhsa04015Rap1 signaling pathway4.83E-038P20827, Q9NRA1, P49767, P11215, Q13009, P42338, P0DP23, P19174EFNA1, PDGFC, VEGFC, ITGAM, TIAM1, PIK3CB, CALM1, PLCG1More
Mefenamic-acidhsa04020Calcium signaling pathway2.61E-026P27987, P21796, P19174, P0DP23, Q9NRA1, P49767ITPKB, VDAC1, PLCG1, CALM1, PDGFC, VEGFCMore
Mefenamic-acidhsa04024cAMP signaling pathway4.38E-024P42338, P0DP23, Q13370, Q13009PIK3CB, CALM1, PDE3B, TIAM1More
Mefenamic-acidhsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, P25025, P14784CXCL1, CXCL2, CXCR1, CXCR2, IL2RBMore
Mefenamic-acidhsa04062Chemokine signaling pathway2.81E-0515P25024, P25025, P09341, P19875, P07948, P42338, P19174, P62873, P63218, P50151, P43250, Q13009, P14598, P42224, P25963CXCR1, CXCR2, CXCL1, CXCL2, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, TIAM1, NCF1, STAT1, NFKBIAMore
Mefenamic-acidhsa04064NF-kappa B signaling pathway1.74E-0513P10415, O00463, P14778, P19174, Q04759, Q9UDY8, Q16548, P06239, Q13315, P24522, P09341, P19875, Q06643BCL2, TRAF5, IL1R1, PLCG1, PRKCQ, MALT1, BCL2A1, LCK, ATM, GADD45A, CXCL1, CXCL2, LTBMore
Mefenamic-acidhsa04070Phosphatidylinositol signaling system1.45E-035P19174, P0DP23, P42338, P23743, P27987PLCG1, CALM1, PIK3CB, DGKA, ITPKBMore
Mefenamic-acidhsa04071Sphingolipid signaling pathway9.35E-058P17252, P21453, Q9H228, Q13362, Q16537, Q9BX95, P04637, P10415PRKCA, S1PR1, EDG8, PPP2R5C, PPP2R5E, SGPP1, TP53, BCL2More
Mefenamic-acidhsa04072Phospholipase D signaling pathway5.49E-038P42338, P43657, P25024, P25025, P19174, Q14344, P23743, Q9NRA1PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1, GNA13, DGKA, PDGFCMore
Mefenamic-acidhsa04080Neuroactive ligand-receptor interaction1.05E-038P08311, Q15722, P21453, Q9H228, O00398, P21730, Q16581, P07550CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, C3AR1, ADRB2More
Mefenamic-acidhsa04115p53 signaling pathway3.98E-025P24522, Q13315, Q53FA7, O95067, P10415GADD45A, ATM, TP53I3, CCNB2, BCL2More
Mefenamic-acidhsa04136Autophagy - other5.92E-032O94817, Q9H1Y0ATG12, ATG5More
Mefenamic-acidhsa04140Autophagy - animal3.19E-024P22694, Q14643, P10415, Q04759PRKACB, ITPR1, BCL2, PRKCQMore
Mefenamic-acidhsa04141Protein processing in endoplasmic reticulum3.42E-047P18848, Q15437, O60337, Q99941, P11142, P07900, Q9NR31ATF4, SEC23B, MARH6, CREBL1, HSPA8, HSP90AA1, SAR1AMore
Mefenamic-acidhsa04145Phagosome4.34E-0710P63261, Q15080, P14598, Q13509, P68371, Q13488, P05164, O60603, P35443, P13765ACTG1, NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, HLA-DOBMore
Mefenamic-acidhsa04146Peroxisome4.83E-024O96011, P56589, Q9UKG9, O75521PEX11B, PEX3, CROT, ECI2More
Mefenamic-acidhsa04151PI3K-Akt signaling pathway1.17E-0419P62753, P42338, P01106, P27348, P20827, Q9NRA1, P49767, P07900, P08238, P62873, P63218, P50151, O15335, P22105, P14784, P01568, Q99941, P18848, O00141RPS6, PIK3CB, MYC, YWHAQ, EFNA1, PDGFC, VEGFC, HSP90AA1, HSP90AB1, GNB1, GNG5, GNG10, CHAD, TNXB, IL2RB, IFNA21, CREBL1, ATF4, SGKMore
Mefenamic-acidhsa04210Apoptosis3.83E-038Q13315, P10415, O76075, P24522, Q16548, P43234, P18848, Q14643ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ATF4, ITPR1More
Mefenamic-acidhsa04211Longevity regulating pathway2.72E-023P51828, Q99941, P18848ADCY7, CREBL1, ATF4More
Mefenamic-acidhsa04213Longevity regulating pathway - multiple species3.85E-024P42338, Q9Y4H2, P11142, Q13547PIK3CB, IRS2, HSPA8, HDAC1More
Mefenamic-acidhsa04217Necroptosis4.42E-046P07900, P15104, P05141, P01584, P0C0S5, Q13557HSP90AA1, GLUL, SLC25A5, IL1B, H2AFZ, CAMK2DMore
Mefenamic-acidhsa04261Adrenergic signaling in cardiomyocytes1.46E-024P51828, Q99941, P18848, Q13557ADCY7, CREBL1, ATF4, CAMK2DMore
Mefenamic-acidhsa04330Notch signaling pathway3.09E-022P49768, P78504PSEN1, JAG1More
Mefenamic-acidhsa04340Hedgehog signaling pathway3.09E-023P22694, Q13635, P10415PRKACB, PTCH1, BCL2More
Mefenamic-acidhsa04360Axon guidance1.49E-036P16333, P20827, O95631, P42338, P23528, P19174NCK1, EFNA1, NTN1, PIK3CB, CFL1, PLCG1More
Mefenamic-acidhsa04371Apelin signaling pathway2.41E-037P62873, P63218, P50151, Q13370, Q14814, Q14344, P0DP23GNB1, GNG5, GNG10, PDE3B, MEF2D, GNA13, CALM1More
Mefenamic-acidhsa04380Osteoclast differentiation1.02E-026Q9UQC2, Q16539, P14778, O75015, P01375, Q8N149GAB2, MAPK14, IL1R1, FCGR3B, TNF, LILRA2More
Mefenamic-acidhsa04540Gap junction3.53E-024P17252, Q13509, P68371, Q14643PRKCA, TUBB3, TUBB2C, ITPR1More
Mefenamic-acidhsa04610Complement and coagulation cascades2.33E-031P0C0L4C4AMore
Mefenamic-acidhsa04612Antigen processing and presentation3.90E-036P13765, P48382, P26715, P26717, Q13241, P01732HLA-DOB, RFX5, KLRC1, KLRC2, KLRD1, CD8AMore
Mefenamic-acidhsa04613Neutrophil extracellular trap formation4.08E-0420P42338, P19174, P17252, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q6FI13, P62807, Q93079, P21796, P14598, Q15080, P20160, P08311, P21730, P21462, P63261PIK3CB, PLCG1, PRKCA, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, H2AC18; H2AC19, HIST1H2BC, H2BC9, VDAC1, NCF1, NCF4, AZU1, CTSG, C5AR1, FPR1, ACTG1More
Mefenamic-acidhsa04620Toll-like receptor signaling pathway4.00E-024P01568, P42224, P25963, P42338IFNA21, STAT1, NFKBIA, PIK3CBMore
Mefenamic-acidhsa04623Cytosolic DNA-sensing pathway3.67E-022P01568, P25963IFNA21, NFKBIAMore
Mefenamic-acidhsa04625C-type lectin receptor signaling pathway2.21E-038Q9ULY5, P42224, P20749, P25963, P01375, P42338, P0DP23, Q16539CLEC4E, STAT1, BCL3, NFKBIA, TNF, PIK3CB, CALM1, MAPK14More
Mefenamic-acidhsa04640Hematopoietic cell lineage1.37E-027P14778, P27930, P11215, P25063, P07766, P01732, P09564IL1R1, IL1R2, ITGAM, CD24, CD3E, CD8A, CD7More
Mefenamic-acidhsa04650Natural killer cell mediated cytotoxicity2.57E-0410P19174, P06239, O60880, P20963, P42338, Q13241, P26718, O14931, P26717, P26715PLCG1, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3, KLRC2, KLRC1More
Mefenamic-acidhsa04657IL-17 signaling pathway1.14E-037P07900, O00463, Q16539, P49841, P14780, P01375, P01584HSP90AA1, TRAF5, MAPK14, GSK3B, MMP9, TNF, IL1BMore
Mefenamic-acidhsa04658Th1 and Th2 cell differentiation2.87E-0814P25963, Q04759, P07766, P20963, P09693, P19174, P06239, P42224, Q14765, P23771, Q9UL17, P14784, P13765, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, PLCG1, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3More
Mefenamic-acidhsa04659Th17 cell differentiation1.22E-0615P25963, Q04759, P19174, P06239, P42224, P14784, P13765, P14778, P40189, Q9UL17, P23771, P08238, P07766, P09693, P20963NFKBIA, PRKCQ, PLCG1, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL6ST, TBX21, GATA3, HSP90AB1, CD3E, CD3G, CD247More
Mefenamic-acidhsa04660T cell receptor signaling pathway1.09E-0412Q9UDY8, Q04759, P42338, P10747, Q08881, P19174, P07766, P20963, P09693, P01732, Q13191, P06239MALT1, PRKCQ, PIK3CB, CD28, ITK, PLCG1, CD3E, CD247, CD3G, CD8A, CBLB, LCKMore
Mefenamic-acidhsa04662B cell receptor signaling pathway1.12E-025P25963, P42338, P07948, P21854, Q8N149NFKBIA, PIK3CB, LYN, CD72, LILRA2More
Mefenamic-acidhsa04664Fc epsilon RI signaling pathway1.29E-037P01375, Q16539, P42338, Q9UQC2, P07948, P19174, P09917TNF, MAPK14, PIK3CB, GAB2, LYN, PLCG1, ALOX5More
Mefenamic-acidhsa04666Fc gamma R-mediated phagocytosis5.78E-069P07948, P42338, P19174, P23528, P49006, P06396, O14494, P14598, P17252LYN, PIK3CB, PLCG1, CFL1, MARCKSL1, GSN, PLPP1, NCF1, PRKCAMore
Mefenamic-acidhsa04668TNF signaling pathway2.21E-025P01375, O00463, Q16539, P20749, P14780TNF, TRAF5, MAPK14, BCL3, MMP9More
Mefenamic-acidhsa04672Intestinal immune network for IgA production1.62E-023P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Mefenamic-acidhsa04713Circadian entrainment4.00E-024P0DP23, P62873, P63218, P50151CALM1, GNB1, GNG5, GNG10More
Mefenamic-acidhsa04714Thermogenesis3.31E-024P51828, P62753, P12074, O15239ADCY7, RPS6, COX6A1, NDUFA1More
Mefenamic-acidhsa04721Synaptic vesicle cycle3.09E-022Q99437, P43005ATP6V0B, SLC1A1More
Mefenamic-acidhsa04724Glutamatergic synapse2.92E-024P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Mefenamic-acidhsa04725Cholinergic synapse3.93E-0410P51828, P22694, Q14643, P62873, P63218, P50151, P18848, Q13557, P42338, P10415ADCY7, PRKACB, ITPR1, GNB1, GNG5, GNG10, ATF4, CAMK2D, PIK3CB, BCL2More
Mefenamic-acidhsa04727GABAergic synapse8.14E-034P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Mefenamic-acidhsa04728Dopaminergic synapse4.78E-023Q99941, P18848, Q13557CREBL1, ATF4, CAMK2DMore
Mefenamic-acidhsa04744Phototransduction3.94E-042P62873, P0DP23GNB1, CALM1More
Mefenamic-acidhsa04750Inflammatory mediator regulation of TRP channels8.12E-046P14778, P19174, P42338, P24723, Q04759, P0DP23IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQ, CALM1More
Mefenamic-acidhsa04810Regulation of actin cytoskeleton2.61E-026P12814, Q13009, P42338, P11215, Q14344, Q9NRA1ACTN1, TIAM1, PIK3CB, ITGAM, GNA13, PDGFCMore
Mefenamic-acidhsa04911Insulin secretion4.03E-044P51828, Q99941, P18848, Q13557ADCY7, CREBL1, ATF4, CAMK2DMore
Mefenamic-acidhsa04912GnRH signaling pathway2.17E-023P51828, P18848, Q13557ADCY7, ATF4, CAMK2DMore
Mefenamic-acidhsa04914Progesterone-mediated oocyte maturation4.07E-034P42338, Q13370, P30304, P08238PIK3CB, PDE3B, CDC25A, HSP90AB1More
Mefenamic-acidhsa04915Estrogen signaling pathway9.55E-049P14780, P22694, Q99941, P18848, P51828, P07900, P11142, Q14643, P10415MMP9, PRKACB, CREBL1, ATF4, ADCY7, HSP90AA1, HSPA8, ITPR1, BCL2More
Mefenamic-acidhsa04916Melanogenesis4.80E-024P0DP23, Q9UJU2, P17252, P04628CALM1, LEF1, PRKCA, WNT1More
Mefenamic-acidhsa04918Thyroid hormone synthesis6.10E-046P22694, P51828, Q99941, P18848, Q14643, P02768PRKACB, ADCY7, CREBL1, ATF4, ITPR1, ALBMore
Mefenamic-acidhsa04922Glucagon signaling pathway4.23E-024P22694, P06737, Q12778, Q14643PRKACB, PYGL, FOXO1, ITPR1More
Mefenamic-acidhsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Mefenamic-acidhsa04924Renin secretion8.19E-045P22694, P07550, Q14643, Q13370, P0DP23PRKACB, ADRB2, ITPR1, PDE3B, CALM1More
Mefenamic-acidhsa04925Aldosterone synthesis and secretion1.69E-034Q99941, P18848, P51828, Q13557CREBL1, ATF4, ADCY7, CAMK2DMore
Mefenamic-acidhsa04926Relaxin signaling pathway8.42E-049P25963, P42338, P62873, P63218, P50151, Q99941, P18848, P49767, P51828NFKBIA, PIK3CB, GNB1, GNG5, GNG10, CREBL1, ATF4, VEGFC, ADCY7More
Mefenamic-acidhsa04927Cortisol synthesis and secretion2.37E-045Q14643, Q99941, P18848, P51828, P22694ITPR1, CREBL1, ATF4, ADCY7, PRKACBMore
Mefenamic-acidhsa04928Parathyroid hormone synthesis, secretion and action2.14E-047Q14643, P51828, P22694, P23771, Q99941, P18848, P10415ITPR1, ADCY7, PRKACB, GATA3, CREBL1, ATF4, BCL2More
Mefenamic-acidhsa04932Non-alcoholic fatty liver disease9.70E-034P18848, P01584, P13073, O15239ATF4, IL1B, COX4I1, NDUFA1More
Mefenamic-acidhsa04934Cushing syndrome1.12E-034Q99941, P18848, P51828, Q13557CREBL1, ATF4, ADCY7, CAMK2DMore
Mefenamic-acidhsa04935Growth hormone synthesis, secretion and action2.72E-023P51828, Q99941, P18848ADCY7, CREBL1, ATF4More
Mefenamic-acidhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Mefenamic-acidhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Mefenamic-acidhsa04972Pancreatic secretion1.99E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Mefenamic-acidhsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Mefenamic-acidhsa05012Parkinson disease7.03E-0311O15239, P13073, P05141, P21796, P60604, P18848, P19174, P0DP23, Q13557, Q71U36, Q13509NDUFA1, COX4I1, SLC25A5, VDAC1, UBE2G2, ATF4, PLCG1, CALM1, CAMK2D, TUBA1A, TUBB3More
Mefenamic-acidhsa05014Amyotrophic lateral sclerosis2.72E-0210P01375, Q16718, O14521, P36542, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, SDHD, ATP5C1, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Mefenamic-acidhsa05016Huntington disease3.21E-025O15239, P13073, P30876, P62487, P05141NDUFA1, COX4I1, POLR2B, POLR2G, SLC25A5More
Mefenamic-acidhsa05020Prion disease3.37E-037P13591, P01584, P11142, O15239, P13073, P18848, P05141NCAM1, IL1B, HSPA8, NDUFA1, COX4I1, ATF4, SLC25A5More
Mefenamic-acidhsa05022Pathways of neurodegeneration - multiple diseases3.80E-026O15239, P13073, P18848, P05141, P01584, Q13557NDUFA1, COX4I1, ATF4, SLC25A5, IL1B, CAMK2DMore
Mefenamic-acidhsa05030Cocaine addiction4.87E-022Q99941, P18848CREBL1, ATF4More
Mefenamic-acidhsa05031Amphetamine addiction6.41E-033Q13557, Q99941, P18848CAMK2D, CREBL1, ATF4More
Mefenamic-acidhsa05032Morphine addiction7.60E-035P62873, P63218, P50151, Q13370, P43250GNB1, GNG5, GNG10, PDE3B, GRK6More
Mefenamic-acidhsa05034Alcoholism6.32E-037Q13547, P0DP23, P62873, P63218, P50151, P62807, Q93079HDAC1, CALM1, GNB1, GNG5, GNG10, HIST1H2BC, H2BC9More
Mefenamic-acidhsa05120Epithelial cell signaling in Helicobacter pylori infection2.44E-047Q99437, P09341, P19875, P10145, P19174, P25024, P25025ATP6V0B, CXCL1, CXCL2, IL8, PLCG1, CXCR1, CXCR2More
Mefenamic-acidhsa05132Salmonella infection1.62E-0417P51617, P25963, P08238, Q9UJU2, P01106, P63261, P42338, Q13489, P10415, O75369, O60603, Q9BQS8, Q13561, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, HSP90AB1, LEF1, MYC, ACTG1, PIK3CB, BIRC3, BCL2, FLNB, TLR2, FYCO1, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41More
Mefenamic-acidhsa05133Pertussis4.20E-021P0C0L4C4AMore
Mefenamic-acidhsa05134Legionellosis6.38E-046P01584, P11215, P68104, P11142, P09341, P19875IL1B, ITGAM, EEF1A1, HSPA8, CXCL1, CXCL2More
Mefenamic-acidhsa05140Leishmaniasis4.13E-025P14598, P13765, O60603, P49006, Q15080NCF1, HLA-DOB, TLR2, MARCKSL1, NCF4More
Mefenamic-acidhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Mefenamic-acidhsa05144Malaria3.09E-022P69905, P68871HBA2, HBBMore
Mefenamic-acidhsa05146Amoebiasis2.21E-048P09341, P19875, P14778, P27930, P42338, P11215, P05089, P12814CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, ACTN1More
Mefenamic-acidhsa05150Staphylococcus aureus infection4.02E-036P21462, O75015, Q14532, P59665, P59666, P12838FPR1, FCGR3B, KRT32, DEFA1; DEFA1B, DEFA3, DEFA4More
Mefenamic-acidhsa05152Tuberculosis5.68E-039Q13488, P0DP23, P48382, O60603, P10415, P13765, P01568, Q9UDY8, P51617TCIRG1, CALM1, RFX5, TLR2, BCL2, HLA-DOB, IFNA21, MALT1, IRAK1More
Mefenamic-acidhsa05161Hepatitis B3.34E-023Q99941, P18848, P27348CREBL1, ATF4, YWHAQMore
Mefenamic-acidhsa05162Measles1.56E-039P01568, P25963, P42224, P14784, P07766, P42338, P11142, P01584, Q9NP90IFNA21, NFKBIA, STAT1, IL2RB, CD3E, PIK3CB, HSPA8, IL1B, RAB9BMore
Mefenamic-acidhsa05163Human cytomegalovirus infection4.95E-0516P42338, P01375, P25963, P62873, P63218, P50151, P0DP23, Q14344, P49841, P01106, P14778, P25025, Q16539, O00463, P30101, P01568PIK3CB, TNF, NFKBIA, GNB1, GNG5, GNG10, CALM1, GNA13, GSK3B, MYC, IL1R1, CXCR2, MAPK14, TRAF5, PDIA3, IFNA21More
Mefenamic-acidhsa05167Kaposi sarcoma-associated herpesvirus infection7.49E-0511P01568, P42224, P25963, P42338, P62873, P63218, P50151, P19174, P07948, P01106, P0DP23IFNA21, STAT1, NFKBIA, PIK3CB, GNB1, GNG5, GNG10, PLCG1, LYN, MYC, CALM1More
Mefenamic-acidhsa05168Herpes simplex virus 1 infection2.16E-0312P25963, P01568, P42224, Q07955, Q01130, Q13243, P30101, P42338, Q13398, Q03923, O75820, Q9UDV6NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, PDIA3, PIK3CB, ZNF211, ZNF85, ZNF189, ZNF212More
Mefenamic-acidhsa05169Epstein-Barr virus infection1.08E-0311P01106, Q13547, P25963, P42338, P07948, P30101, Q13761, O75293, P42224, P01568, P07766MYC, HDAC1, NFKBIA, PIK3CB, LYN, PDIA3, RUNX3, GADD45B, STAT1, IFNA21, CD3EMore
Mefenamic-acidhsa05170Human immunodeficiency virus 1 infection7.42E-0519P42338, P62873, P63218, P50151, P0DP23, P17252, O00463, P30101, Q14643, P01568, P51617, P25963, O60603, P19174, P23528, P07766, P10415, Q93034, Q9Y6Q5PIK3CB, GNB1, GNG5, GNG10, CALM1, PRKCA, TRAF5, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, PLCG1, CFL1, CD3E, BCL2, CUL5, AP1M2More
Mefenamic-acidhsa05171Coronavirus disease - COVID-199.72E-037P01584, P62753, P25398, P36578, P32969, P18077, P62829IL1B, RPS6, RPS12, RPL4, RPL9, RPL35A, RPL23More
Mefenamic-acidhsa05200Pathways in cancer2.72E-0419P42338, P08238, P42224, P25963, P19174, P01106, P43246, Q13547, P14923, P49767, P62873, P63218, P50151, Q14344, O75293, P0DP23, P01568, P14784, P40189PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, MSH2, HDAC1, JUP, VEGFC, GNB1, GNG5, GNG10, GNA13, GADD45B, CALM1, IFNA21, IL2RB, IL6STMore
Mefenamic-acidhsa05202Transcriptional misregulation in cancer6.55E-0618Q12778, Q15532, Q13315, P41732, P14780, P14923, Q15744, Q16548, Q13489, Q13077, O15550, P04637, P35226, P05164, P12838, P08246, Q9C0K0, P24522FOXO1, SS18, ATM, TSPAN7, MMP9, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, UTX, TP53, BMI1, MPO, DEFA4, ELA2, BCL11B, GADD45AMore
Mefenamic-acidhsa05203Viral carcinogenesis1.11E-0516Q12933, Q99941, P18848, P42229, P42338, P06746, P07948, P27348, P29083, Q13547, Q15283, P12814, P25963, P61978, P62807, Q93079TRAF2, CREBL1, ATF4, STAT5A, PIK3CB, POLB, LYN, YWHAQ, GTF2E1, HDAC1, RASA2, ACTN1, NFKBIA, HNRPK, HIST1H2BC, H2BC9More
Mefenamic-acidhsa05204Chemical carcinogenesis5.46E-032Q16772, P09211GSTA3, GSTP1More
Mefenamic-acidhsa05205Proteoglycans in cancer9.14E-0412Q13009, Q12955, Q14643, O75369, P63261, P04637, P14780, P17252, O60603, P04628, Q13635, P08962TIAM1, ANK3, ITPR1, FLNB, ACTG1, TP53, MMP9, PRKCA, TLR2, WNT1, PTCH1, CD63More
Mefenamic-acidhsa05206MicroRNAs in cancer2.79E-027P30304, P09493, P01106, P42338, Q13547, P20827, P19174CDC25A, TPM1, MYC, PIK3CB, HDAC1, EFNA1, PLCG1More
Mefenamic-acidhsa05212Pancreatic cancer1.72E-023P42338, P42224, O75293PIK3CB, STAT1, GADD45BMore
Mefenamic-acidhsa05214Glioma5.98E-044P0DP23, P42338, P19174, O75293CALM1, PIK3CB, PLCG1, GADD45BMore
Mefenamic-acidhsa05216Thyroid cancer3.59E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Mefenamic-acidhsa05217Basal cell carcinoma1.46E-024Q13635, Q9UJU2, P04637, P24522PTCH1, LEF1, TP53, GADD45AMore
Mefenamic-acidhsa05218Melanoma2.31E-023Q9NRA1, P42338, O75293PDGFC, PIK3CB, GADD45BMore
Mefenamic-acidhsa05220Chronic myeloid leukemia2.17E-025Q13547, P01106, P25963, P42338, O75293HDAC1, MYC, NFKBIA, PIK3CB, GADD45BMore
Mefenamic-acidhsa05231Choline metabolism in cancer2.92E-035P42338, Q9NRA1, Q9Y259, P19174, P23743PIK3CB, PDGFC, CHKB, PLCG1, DGKAMore
Mefenamic-acidhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer7.96E-0511P25963, P42338, P19174, P07766, P20963, P09693, P06239, P42224, O60603, P10747, Q04759NFKBIA, PIK3CB, PLCG1, CD3E, CD247, CD3G, LCK, STAT1, TLR2, CD28, PRKCQMore
Mefenamic-acidhsa05320Autoimmune thyroid disease8.64E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Mefenamic-acidhsa05321Inflammatory bowel disease8.69E-056O60603, P13765, Q14765, Q9UL17, P23771, Q9HBE5TLR2, HLA-DOB, STAT4, TBX21, GATA3, IL21RMore
Mefenamic-acidhsa05323Rheumatoid arthritis1.45E-034P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Mefenamic-acidhsa05332Graft-versus-host disease6.43E-054P13765, P10747, P26715, Q13241HLA-DOB, CD28, KLRC1, KLRD1More
Mefenamic-acidhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Mefenamic-acidhsa05415Diabetic cardiomyopathy2.87E-024P05141, O15239, P13073, Q13557SLC25A5, NDUFA1, COX4I1, CAMK2DMore
Mefenamic-acidhsa05418Fluid shear stress and atherosclerosis3.01E-0515Q16539, P42338, Q14145, P14598, P10599, P14780, P01375, P63261, P04637, P10415, P14778, P27930, P0DP23, P08238, Q92974MAPK14, PIK3CB, KEAP1, NCF1, TXN, MMP9, TNF, ACTG1, TP53, BCL2, IL1R1, IL1R2, CALM1, HSP90AB1, ARHGEF2More

Community members of Mefenamic-acid (SDC: 6.29)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)