PharmaCoNets
.
Liotrix
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PharmaCoNets of Liotrix (S
PCN
: 0.08 )
Liotrix regulated-network (S
DN
: 0.17)
Drug Name
Pathway ID
Pathway name
P-value
No. of gene members
UniProt AC
Gene name
Detail of Coexpression
Liotrix
hsa01524
Platinum drug resistance
1.79E-02
2
O15392, P11388
BIRC5, TOP2A
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q13133
NR1H3
Oxysterols receptor LXR-alpha
O15392
BIRC5
Baculoviral IAP repeat-containing protein 5
-0.744
Q13133
NR1H3
Oxysterols receptor LXR-alpha
P11388
TOP2A
DNA topoisomerase 2-alpha
-0.816
Liotrix
hsa03018
RNA degradation
5.00E-02
1
Q9NQT4
EXOSC5
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q13133
NR1H3
Oxysterols receptor LXR-alpha
Q9NQT4
EXOSC5
Exosome complex component RRP46
0.808
Liotrix
hsa04710
Circadian rhythm
1.67E-02
2
Q16526, Q9Y478
CRY1, PRKAB1
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P10826
RARB
Retinoic acid receptor beta
Q16526
CRY1
Cryptochrome-1
-0.77
P10826
RARB
Retinoic acid receptor beta
Q9Y478
PRKAB1
5'-AMP-activated protein kinase subunit beta-1
-0.711
Liotrix
hsa04920
Adipocytokine signaling pathway
4.31E-02
2
Q9Y478, Q96RR4
PRKAB1, CAMKK2
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P10826
RARB
Retinoic acid receptor beta
Q9Y478
PRKAB1
5'-AMP-activated protein kinase subunit beta-1
-0.711
P10826
RARB
Retinoic acid receptor beta
Q96RR4
CAMKK2
Calcium/calmodulin-dependent protein kinase kinase 2
0.737
Community members of Liotrix (S
DC
: 0.46)
UniProtAC
Gene Name
Protein Name
Reported/
Predicted
DisGeNET
S
PV
S
drugability
S
HiSBiN
S
DisG
P10826
RARB
Retinoic acid receptor beta
Predicted
0
0.0094
0.3466
0.3005
0.9983
BDBM ID
C.S.
Homologus UniProt ID
Gene Name
I.S.
Text mining Similar drug DB ID
C.S.
None
None
P10826
RARB
0.351
None
None
Q13133
NR1H3
Oxysterols receptor LXRNonealpha
Predicted
0
0.0162
0.439
0.2086
1.0947
BDBM ID
C.S.
Homologus UniProt ID
Gene Name
I.S.
Text mining Similar drug DB ID
C.S.
None
None
Q13133
NR1H3
0.347
None
None
This pair is Reported in Drugbank.
Gene name
UniProt_ID
Bioactivity
Value (nM)
