| Lifitegrast | hsa00220 | Arginine biosynthesis | 1.21E-02 | 1 | P15104 | GLUL | More | |
| Lifitegrast | hsa00230 | Purine metabolism | 1.56E-02 | 3 | Q7LG56, P51828, Q9Y227 | RRM2B, ADCY7, ENTPD4 | More | |
| Lifitegrast | hsa00240 | Pyrimidine metabolism | 1.45E-02 | 2 | Q7LG56, Q9Y227 | RRM2B, ENTPD4 | More | |
| Lifitegrast | hsa00250 | Alanine, aspartate and glutamate metabolism | 2.42E-02 | 1 | P15104 | GLUL | More | |
| Lifitegrast | hsa00280 | Valine, leucine and isoleucine degradation | 4.31E-02 | 2 | P26440, Q02252 | IVD, ALDH6A1 | More | |
| Lifitegrast | hsa00520 | Amino sugar and nucleotide sugar metabolism | 2.24E-02 | 3 | Q16222, Q9Y223, P06865 | UAP1, GNE, HEXA | More | |
| Lifitegrast | hsa00564 | Glycerophospholipid metabolism | 2.28E-02 | 3 | Q9Y259, P23743, Q3LIE5 | CHKB, DGKA, ADPRM | More | |
| Lifitegrast | hsa00590 | Arachidonic acid metabolism | 3.85E-02 | 2 | P11712, P09960 | CYP2C9, LTA4H | More | |
| Lifitegrast | hsa00591 | Linoleic acid metabolism | 4.07E-02 | 1 | P11712 | CYP2C9 | More | |
| Lifitegrast | hsa00630 | Glyoxylate and dicarboxylate metabolism | 9.21E-03 | 2 | P40925, P15104 | MDH1, GLUL | More | |
| Lifitegrast | hsa00860 | Porphyrin and chlorophyll metabolism | 5.29E-03 | 2 | P53004, P30043 | BLVRA, BLVRB | More | |
| Lifitegrast | hsa00910 | Nitrogen metabolism | 2.42E-02 | 1 | P15104 | GLUL | More | |
| Lifitegrast | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 9.14E-03 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | |
| Lifitegrast | hsa00982 | Drug metabolism - cytochrome P450 | 9.14E-03 | 2 | P11712, P78417 | CYP2C9, GSTO1 | More | |
| Lifitegrast | hsa01210 | 2-Oxocarboxylic acid metabolism | 3.43E-02 | 1 | P50213 | IDH3A | More | |
| Lifitegrast | hsa01230 | Biosynthesis of amino acids | 5.53E-03 | 2 | P15104, P37837 | GLUL, TALDO1 | More | |
| Lifitegrast | hsa03030 | DNA replication | 5.00E-02 | 1 | P27694 | RPA1 | More | |
| Lifitegrast | hsa03040 | Spliceosome | 1.08E-02 | 7 | O43143, P08579, Q07955, P84103, Q13243, P11142, O75643 | DHX15, SNRPB2, SFRS1, SFRS3, SFRS5, HSPA8, ASCC3L1 | More | |
| Lifitegrast | hsa03060 | Protein export | 1.90E-02 | 2 | Q15070, O76094 | OXA1L, SRP72 | More | |
| Lifitegrast | hsa03450 | Non-homologous end-joining | 4.32E-02 | 1 | Q9NP87 | POLM | More | |
| Lifitegrast | hsa04012 | ErbB signaling pathway | 4.75E-02 | 3 | P16333, P19174, P01106 | NCK1, PLCG1, MYC | More | |
| Lifitegrast | hsa04120 | Ubiquitin mediated proteolysis | 4.61E-02 | 2 | Q13042, Q15751 | CDC16, HERC1 | More | |
| Lifitegrast | hsa04141 | Protein processing in endoplasmic reticulum | 2.78E-02 | 3 | P07384, O95487, O95816 | CAPN1, SEC24B, BAG2 | More | |
| Lifitegrast | hsa04142 | Lysosome | 2.08E-03 | 6 | Q99437, P25774, P22304, Q13510, Q04900, Q9Y227 | ATP6V0B, CTSS, IDS, ASAH1, CD164, ENTPD4 | More | |
| Lifitegrast | hsa04144 | Endocytosis | 2.25E-02 | 5 | O75351, P42566, Q15438, Q14161, Q9UNH7 | VPS4B, EPS15, PSCD1, GIT2, SNX6 | More | |
| Lifitegrast | hsa04145 | Phagosome | 3.11E-02 | 2 | Q99437, P25774 | ATP6V0B, CTSS | More | |
| Lifitegrast | hsa04360 | Axon guidance | 1.50E-02 | 3 | P20827, P23528, Q06124 | EFNA1, CFL1, PTPN11 | More | |
| Lifitegrast | hsa04514 | Cell adhesion molecules | 1.22E-02 | 2 | P23229, P30511 | ITGA6, HLA-F | More | |
| Lifitegrast | hsa04530 | Tight junction | 1.74E-03 | 6 | P63261, P16989, P56750, Q9Y478, Q92974, Q14247 | ACTG1, CSDA, CLDN17, PRKAB1, ARHGEF2, CTTN | More | |
| Lifitegrast | hsa04610 | Complement and coagulation cascades | 3.16E-03 | 2 | P00734, P0C0L4 | F2, C4A | More | |
| Lifitegrast | hsa04613 | Neutrophil extracellular trap formation | 1.73E-02 | 4 | Q93077, P62807, O60814, P68431 | HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | |
| Lifitegrast | hsa04650 | Natural killer cell mediated cytotoxicity | 2.95E-02 | 7 | P06239, P20963, Q13241, P26718, O14931, P26717, P26715 | LCK, CD247, KLRD1, KLRK1, NCR3, KLRC2, KLRC1 | More | |
| Lifitegrast | hsa04658 | Th1 and Th2 cell differentiation | 2.59E-04 | 10 | P07766, P20963, P09693, P19174, P06239, P42224, P23771, Q9UL17, P14784, Q13761 | CD3E, CD247, CD3G, PLCG1, LCK, STAT1, GATA3, TBX21, IL2RB, RUNX3 | More | |
| Lifitegrast | hsa04659 | Th17 cell differentiation | 4.36E-02 | 5 | P19174, P42224, P14784, P08238, P07766 | PLCG1, STAT1, IL2RB, HSP90AB1, CD3E | More | |
| Lifitegrast | hsa04660 | T cell receptor signaling pathway | 1.13E-02 | 8 | O95267, Q08881, P07766, P20963, P09693, P01732, Q13191, P06239 | RASGRP1, ITK, CD3E, CD247, CD3G, CD8A, CBLB, LCK | More | |
| Lifitegrast | hsa04664 | Fc epsilon RI signaling pathway | 4.75E-02 | 3 | P07948, P19174, P09917 | LYN, PLCG1, ALOX5 | More | |
| Lifitegrast | hsa04714 | Thermogenesis | 1.25E-02 | 3 | P15336, P63261, Q9Y478 | ATF2, ACTG1, PRKAB1 | More | |
| Lifitegrast | hsa04727 | GABAergic synapse | 3.40E-02 | 3 | P63218, P50151, P15104 | GNG5, GNG10, GLUL | More | |
| Lifitegrast | hsa04730 | Long-term depression | 5.00E-02 | 1 | Q14344 | GNA13 | More | |
| Lifitegrast | hsa04810 | Regulation of actin cytoskeleton | 2.68E-02 | 2 | P23229, Q14344 | ITGA6, GNA13 | More | |
| Lifitegrast | hsa04912 | GnRH signaling pathway | 2.01E-02 | 3 | P51828, P0DP24, P45985 | ADCY7, CALM2, MAP2K4 | More | |
| Lifitegrast | hsa04920 | Adipocytokine signaling pathway | 2.80E-02 | 2 | Q06124, Q9Y478 | PTPN11, PRKAB1 | More | |
| Lifitegrast | hsa04970 | Salivary secretion | 4.61E-02 | 2 | P51828, P0DP24 | ADCY7, CALM2 | More | |
| Lifitegrast | hsa05034 | Alcoholism | 1.19E-04 | 7 | Q13547, P63218, P50151, Q93077, P62807, O60814, P68431 | HDAC1, GNG5, GNG10, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | |
| Lifitegrast | hsa05110 | Vibrio cholerae infection | 4.78E-02 | 1 | Q99437 | ATP6V0B | More | |
| Lifitegrast | hsa05130 | Pathogenic Escherichia coli infection | 9.80E-03 | 4 | Q92974, P63261, Q06124, O95487 | ARHGEF2, ACTG1, PTPN11, SEC24B | More | |
| Lifitegrast | hsa05133 | Pertussis | 2.24E-02 | 2 | P0DP23, P0C0L4 | CALM1, C4A | More | |
| Lifitegrast | hsa05143 | African trypanosomiasis | 4.81E-02 | 2 | P69905, P68871 | HBA2, HBB | More | |
| Lifitegrast | hsa05145 | Toxoplasmosis | 3.59E-02 | 5 | P42224, P09917, Q13751, P11142, Q13651 | STAT1, ALOX5, LAMB3, HSPA8, IL10RA | More | |
| Lifitegrast | hsa05152 | Tuberculosis | 4.16E-02 | 2 | Q99437, P25774 | ATP6V0B, CTSS | More | |
| Lifitegrast | hsa05163 | Human cytomegalovirus infection | 4.31E-02 | 2 | P30511, Q14344 | HLA-F, GNA13 | More | |
| Lifitegrast | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 3.79E-02 | 6 | P42224, P63218, P50151, P19174, P07948, P01106 | STAT1, GNG5, GNG10, PLCG1, LYN, MYC | More | |
| Lifitegrast | hsa05169 | Epstein-Barr virus infection | 1.43E-02 | 8 | P01106, Q13547, P07948, P30101, Q13761, O75293, P42224, P07766 | MYC, HDAC1, LYN, PDIA3, RUNX3, GADD45B, STAT1, CD3E | More | |
| Lifitegrast | hsa05200 | Pathways in cancer | 5.69E-03 | 14 | Q13751, P08238, P42224, P19174, P01106, P43246, P20585, Q13547, P49767, P63218, P50151, P78417, O75293, P14784 | LAMB3, HSP90AB1, STAT1, PLCG1, MYC, MSH2, MSH3, HDAC1, VEGFC, GNG5, GNG10, GSTO1, GADD45B, IL2RB | More | |
| Lifitegrast | hsa05203 | Viral carcinogenesis | 6.58E-03 | 7 | P07948, P29083, Q13547, Q15283, P12814, P62807, O60814 | LYN, GTF2E1, HDAC1, RASA2, ACTN1, HIST1H2BC, H2BC12 | More | |
| Lifitegrast | hsa05204 | Chemical carcinogenesis | 1.48E-02 | 2 | P78417, P11712 | GSTO1, CYP2C9 | More | |
| Lifitegrast | hsa05206 | MicroRNAs in cancer | 3.79E-02 | 6 | P30304, P09493, P01106, Q9Y4H2, Q13547, P19174 | CDC25A, TPM1, MYC, IRS2, HDAC1, PLCG1 | More | |
| Lifitegrast | hsa05211 | Renal cell carcinoma | 1.06E-02 | 2 | Q06124, Q99814 | PTPN11, EPAS1 | More | |
| Lifitegrast | hsa05231 | Choline metabolism in cancer | 1.08E-02 | 4 | O15245, Q9Y259, P19174, P23743 | SLC22A1, CHKB, PLCG1, DGKA | More | |
| Lifitegrast | hsa05322 | Systemic lupus erythematosus | 1.31E-04 | 5 | P09871, Q93077, P62807, O60814, P68431 | C1S, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12 | More | |
