PharmaCoNets of Lenvatinib (SPCN: 90.59 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Lenvatinibhsa00071Fatty acid degradation3.50E-024O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Lenvatinibhsa00220Arginine biosynthesis3.83E-022P05089, P49448ARG1, GLUD2More
Lenvatinibhsa00310Lysine degradation1.31E-032Q96KQ7, P51648EHMT2, ALDH3A2More
Lenvatinibhsa00500Starch and sucrose metabolism2.67E-021P35573AGLMore
Lenvatinibhsa00512Mucin type O-glycan biosynthesis4.86E-022O95395, Q9NY28GCNT3, GALNT8More
Lenvatinibhsa00564Glycerophospholipid metabolism1.38E-023P48651, Q9Y6K0, P35790PTDSS1, CEPT1, CHKAMore
Lenvatinibhsa00630Glyoxylate and dicarboxylate metabolism1.03E-042P40925, P15104MDH1, GLULMore
Lenvatinibhsa00830Retinol metabolism2.27E-035P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Lenvatinibhsa01521EGFR tyrosine kinase inhibitor resistance1.82E-021P04049RAF1More
Lenvatinibhsa01522Endocrine resistance2.16E-021P04049RAF1More
Lenvatinibhsa02010ABC transporters4.48E-021Q8IZY2ABCA7More
Lenvatinibhsa03040Spliceosome9.64E-0613Q14562, O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, ASCC3L1More
Lenvatinibhsa04010MAPK signaling pathway4.15E-021P04049RAF1More
Lenvatinibhsa04012ErbB signaling pathway1.82E-021P04049RAF1More
Lenvatinibhsa04014Ras signaling pathway3.82E-038P04049, Q9NRA1, Q13009, P0DP23, P62873, P63218, P50151, P19174RAF1, PDGFC, TIAM1, CALM1, GNB1, GNG5, GNG10, PLCG1More
Lenvatinibhsa04015Rap1 signaling pathway2.99E-021P04049RAF1More
Lenvatinibhsa04022cGMP-PKG signaling pathway3.15E-021P04049RAF1More
Lenvatinibhsa04024cAMP signaling pathway2.49E-021P04049RAF1More
Lenvatinibhsa04060Cytokine-cytokine receptor interaction5.34E-0311P14784, P27930, P14778, P26842, Q06643, Q13651, P25024, Q9UBD3, P47992, P09341, P01730IL2RB, IL1R2, IL1R1, CD27, LTB, IL10RA, CXCR1, XCL2, XCL1, CXCL1, CD4More
Lenvatinibhsa04061Viral protein interaction with cytokine and cytokine receptor1.32E-026P09341, P25024, P47992, Q9UBD3, Q13651, P14784CXCL1, CXCR1, XCL1, XCL2, IL10RA, IL2RBMore
Lenvatinibhsa04062Chemokine signaling pathway1.82E-0516P25024, P09341, P47992, Q9UBD3, P07948, P19174, P62873, P63218, P50151, P43250, Q08881, Q13009, P14598, P42224, P04049, P25963CXCR1, CXCL1, XCL1, XCL2, LYN, PLCG1, GNB1, GNG5, GNG10, GRK6, ITK, TIAM1, NCF1, STAT1, RAF1, NFKBIAMore
Lenvatinibhsa04064NF-kappa B signaling pathway5.48E-0720P10415, Q12933, O00463, P14778, P01584, P01375, Q04759, Q9UDY8, Q13077, P10145, P19784, Q16548, P07948, P06239, Q8WV28, Q13315, P24522, P09341, Q06643, Q9NQC7BCL2, TRAF2, TRAF5, IL1R1, IL1B, TNF, PRKCQ, MALT1, TRAF1, IL8, CSNK2A2, BCL2A1, LYN, LCK, BLNK, ATM, GADD45A, CXCL1, LTB, CYLDMore
Lenvatinibhsa04068FoxO signaling pathway1.99E-021P04049RAF1More
Lenvatinibhsa04070Phosphatidylinositol signaling system2.93E-024P19174, P0DP23, P23743, P27987PLCG1, CALM1, DGKA, ITPKBMore
Lenvatinibhsa04071Sphingolipid signaling pathway4.86E-036P04049, P21453, Q9H228, Q13362, Q9BX95, P10415RAF1, S1PR1, EDG8, PPP2R5C, SGPP1, BCL2More
Lenvatinibhsa04072Phospholipase D signaling pathway2.82E-021P04049RAF1More
Lenvatinibhsa04080Neuroactive ligand-receptor interaction1.00E-027P08311, Q15722, P21453, Q9H228, O00398, P21730, P07550CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, ADRB2More
Lenvatinibhsa04140Autophagy - animal2.95E-025P04049, P22694, Q14643, P10415, Q04759RAF1, PRKACB, ITPR1, BCL2, PRKCQMore
Lenvatinibhsa04141Protein processing in endoplasmic reticulum8.60E-036P30101, P60604, P11142, P08238, Q9H173, Q9UNL2PDIA3, UBE2G2, HSPA8, HSP90AB1, SIL1, SSR3More
Lenvatinibhsa04144Endocytosis2.81E-026Q13191, P11142, P25024, P43250, P14784, Q9Y5X3CBLB, HSPA8, CXCR1, GRK6, IL2RB, SNX5More
Lenvatinibhsa04145Phagosome9.44E-0411P11215, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, P05164, O60603, P35443, P13765ITGAM, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, MPO, TLR2, THBS4, HLA-DOBMore
Lenvatinibhsa04150mTOR signaling pathway2.32E-021P04049RAF1More
Lenvatinibhsa04210Apoptosis3.76E-038Q13315, P10415, O76075, P24522, Q16548, P43234, Q14643, P04049ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ITPR1, RAF1More
Lenvatinibhsa04218Cellular senescence2.49E-021P04049RAF1More
Lenvatinibhsa04260Cardiac muscle contraction4.70E-022P09493, P14927TPM1, UQCRBMore
Lenvatinibhsa04270Vascular smooth muscle contraction2.32E-021P04049RAF1More
Lenvatinibhsa04340Hedgehog signaling pathway3.09E-023P22694, Q13635, P10415PRKACB, PTCH1, BCL2More
Lenvatinibhsa04360Axon guidance2.49E-021P04049RAF1More
Lenvatinibhsa04370VEGF signaling pathway8.29E-031P04049RAF1More
Lenvatinibhsa04371Apelin signaling pathway3.46E-048P62873, P63218, P50151, P04049, Q13370, Q14344, P84022, P0DP23GNB1, GNG5, GNG10, RAF1, PDE3B, GNA13, SMAD3, CALM1More
Lenvatinibhsa04380Osteoclast differentiation2.05E-0312Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P01584, P14778, O75015, Q8WV28, P01375, Q15080, P78324CYLD, GAB2, MAPK14, JAK1, LCK, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, SIRPAMore
Lenvatinibhsa04510Focal adhesion3.48E-021P04049RAF1More
Lenvatinibhsa04540Gap junction2.22E-035Q13509, P68371, Q71U36, P04049, Q9NRA1TUBB3, TUBB2C, TUBA1A, RAF1, PDGFCMore
Lenvatinibhsa04550Signaling pathways regulating pluripotency of stem cells1.99E-021P04049RAF1More
Lenvatinibhsa04610Complement and coagulation cascades2.30E-062P0C0L4, P05107C4A, ITGB2More
Lenvatinibhsa04612Antigen processing and presentation2.20E-036P13765, P01730, P26715, P26717, Q13241, P01732HLA-DOB, CD4, KLRC1, KLRC2, KLRD1, CD8AMore
Lenvatinibhsa04613Neutrophil extracellular trap formation6.02E-0416P04049, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P0C0S5, Q15080, P20160, P08311, O75015, P21730, P21462, O43315, Q16539RAF1, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AFZ, NCF4, AZU1, CTSG, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Lenvatinibhsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Lenvatinibhsa04622RIG-I-like receptor signaling pathway1.06E-022Q12933, P10145TRAF2, IL8More
Lenvatinibhsa04623Cytosolic DNA-sensing pathway2.59E-022P01568, P25963IFNA21, NFKBIAMore
Lenvatinibhsa04625C-type lectin receptor signaling pathway1.88E-0310Q9ULY5, P04049, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P0DP24, Q16539CLEC4E, RAF1, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, CALM2, MAPK14More
Lenvatinibhsa04630JAK-STAT signaling pathway1.49E-021P04049RAF1More
Lenvatinibhsa04640Hematopoietic cell lineage1.16E-0414P13612, P14778, P27930, P15144, P11836, P25063, P07766, P09693, P01732, P01730, P09564, P13765, P01375, P01584ITGA4, IL1R1, IL1R2, ANPEP, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD7, HLA-DOB, TNF, IL1BMore
Lenvatinibhsa04650Natural killer cell mediated cytotoxicity8.66E-0612P01375, P78314, P06239, O60880, P20963, P04049, Q13241, P26718, O14931, O75015, P26717, P26715TNF, SH3BP2, LCK, SH2D1A, CD247, RAF1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC1More
Lenvatinibhsa04657IL-17 signaling pathway1.56E-028O00463, Q16539, P49841, P09341, P14780, P80188, P01375, P01584TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF, IL1BMore
Lenvatinibhsa04658Th1 and Th2 cell differentiation1.66E-1014Q04759, P07766, P20963, P09693, Q16539, P01730, P06239, Q14765, P23771, Q9UL17, P14784, P13765, P23458, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, CD4, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, JAK1, RUNX3More
Lenvatinibhsa04659Th17 cell differentiation1.26E-1020P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9UL17, P23771, P84022, Q13485, P01584, P08238, P07766, P09693, P20963, P23458NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, TBX21, GATA3, SMAD3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Lenvatinibhsa04660T cell receptor signaling pathway2.43E-0716P01375, Q9UDY8, Q04759, P10747, O95267, Q08881, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P04049, Q16539, P49841TNF, MALT1, PRKCQ, CD28, RASGRP1, ITK, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, RAF1, MAPK14, GSK3BMore
Lenvatinibhsa04662B cell receptor signaling pathway4.47E-035P42338, P60033, P07948, Q8N149, P04049PIK3CB, CD81, LYN, LILRA2, RAF1More
Lenvatinibhsa04664Fc epsilon RI signaling pathway1.24E-035P04141, P07948, P19174, P04049, P09917CSF2, LYN, PLCG1, RAF1, ALOX5More
Lenvatinibhsa04666Fc gamma R-mediated phagocytosis2.32E-021P04049RAF1More
Lenvatinibhsa04713Circadian entrainment2.18E-024P0DP23, P62873, P63218, P50151CALM1, GNB1, GNG5, GNG10More
Lenvatinibhsa04720Long-term potentiation1.66E-021P04049RAF1More
Lenvatinibhsa04722Neurotrophin signaling pathway2.32E-021P04049RAF1More
Lenvatinibhsa04724Glutamatergic synapse8.84E-045O15399, P62873, P63218, P50151, P15104GRIN2D, GNB1, GNG5, GNG10, GLULMore
Lenvatinibhsa04726Serotonergic synapse5.74E-035P62873, P63218, P50151, P09917, P04049GNB1, GNG5, GNG10, ALOX5, RAF1More
Lenvatinibhsa04727GABAergic synapse5.11E-044P62873, P63218, P50151, P15104GNB1, GNG5, GNG10, GLULMore
Lenvatinibhsa04730Long-term depression1.95E-023Q14344, P04049, P07948GNA13, RAF1, LYNMore
Lenvatinibhsa04744Phototransduction9.21E-032P62873, P0DP23GNB1, CALM1More
Lenvatinibhsa04750Inflammatory mediator regulation of TRP channels1.17E-028P14778, P01584, P51828, P22694, Q16539, Q14643, Q04759, P0DP24IL1R1, IL1B, ADCY7, PRKACB, MAPK14, ITPR1, PRKCQ, CALM2More
Lenvatinibhsa04810Regulation of actin cytoskeleton3.81E-021P04049RAF1More
Lenvatinibhsa04910Insulin signaling pathway1.49E-021P04049RAF1More
Lenvatinibhsa04912GnRH signaling pathway2.74E-027P51828, Q16539, Q9Y6R4, Q14643, P0DP24, P22694, P04049ADCY7, MAPK14, MAP3K4, ITPR1, CALM2, PRKACB, RAF1More
Lenvatinibhsa04914Progesterone-mediated oocyte maturation2.16E-021P04049RAF1More
Lenvatinibhsa04915Estrogen signaling pathway2.99E-021P04049RAF1More
Lenvatinibhsa04916Melanogenesis1.33E-021P04049RAF1More
Lenvatinibhsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Lenvatinibhsa04919Thyroid hormone signaling pathway1.82E-021P04049RAF1More
Lenvatinibhsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Lenvatinibhsa04922Glucagon signaling pathway4.23E-024P22694, P06737, Q12778, Q14643PRKACB, PYGL, FOXO1, ITPR1More
Lenvatinibhsa04924Renin secretion1.04E-023P22694, P07550, Q14643PRKACB, ADRB2, ITPR1More
Lenvatinibhsa04926Relaxin signaling pathway2.32E-021P04049RAF1More
Lenvatinibhsa04928Parathyroid hormone synthesis, secretion and action1.60E-025Q14643, P22694, P23771, P04049, P10415ITPR1, PRKACB, GATA3, RAF1, BCL2More
Lenvatinibhsa04929GnRH secretion4.98E-031P04049RAF1More
Lenvatinibhsa04935Growth hormone synthesis, secretion and action2.16E-021P04049RAF1More
Lenvatinibhsa04964Proximal tubule bicarbonate reclamation4.48E-021P00918CA2More
Lenvatinibhsa04966Collecting duct acid secretion4.48E-021P00918CA2More
Lenvatinibhsa05012Parkinson disease1.77E-026P60604, P19174, P0DP23, Q71U36, Q13509, P68371UBE2G2, PLCG1, CALM1, TUBA1A, TUBB3, TUBB2CMore
Lenvatinibhsa05017Spinocerebellar ataxia2.22E-024Q92915, O15399, P42338, P21796FGF14, GRIN2D, PIK3CB, VDAC1More
Lenvatinibhsa05032Morphine addiction2.18E-024P62873, P63218, P50151, Q13370GNB1, GNG5, GNG10, PDE3BMore
Lenvatinibhsa05034Alcoholism2.49E-021P04049RAF1More
Lenvatinibhsa05120Epithelial cell signaling in Helicobacter pylori infection1.08E-024P25963, Q13488, P19174, P07948NFKBIA, TCIRG1, PLCG1, LYNMore
Lenvatinibhsa05130Pathogenic Escherichia coli infection3.19E-026Q71U36, P16333, Q13509, P68371, Q14344, P25963TUBA1A, NCK1, TUBB3, TUBB2C, GNA13, NFKBIAMore
Lenvatinibhsa05132Salmonella infection1.82E-028P25963, P08238, P04049, O75369, Q71U36, Q13509, P68371, P49754NFKBIA, HSP90AB1, RAF1, FLNB, TUBA1A, TUBB3, TUBB2C, VPS41More
Lenvatinibhsa05133Pertussis4.24E-053P05107, P10145, P0C0L4ITGB2, IL8, C4AMore
Lenvatinibhsa05134Legionellosis4.75E-023P25963, P11215, P11142NFKBIA, ITGAM, HSPA8More
Lenvatinibhsa05140Leishmaniasis3.10E-0313P13612, O75015, P14598, P11215, P23458, P42224, P13765, O60603, P25963, P01375, P01584, Q16539, Q15080ITGA4, FCGR3B, NCF1, ITGAM, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, MAPK14, NCF4More
Lenvatinibhsa05143African trypanosomiasis2.03E-022P69905, P68871HBA2, HBBMore
Lenvatinibhsa05144Malaria1.89E-0410P60033, P69905, P68871, O60603, P01375, P05107, P35443, P01584, P10145, P26718CD81, HBA2, HBB, TLR2, TNF, ITGB2, THBS4, IL1B, IL8, KLRK1More
Lenvatinibhsa05146Amoebiasis1.86E-0310P01584, P09341, P14778, P27930, P01375, O60603, P05089, P22694, P12814, P08311IL1B, CXCL1, IL1R1, IL1R2, TNF, TLR2, ARG1, PRKACB, ACTN1, CTSGMore
Lenvatinibhsa05150Staphylococcus aureus infection9.70E-043P0C0L4, P13646, P05107C4A, KRT13, ITGB2More
Lenvatinibhsa05152Tuberculosis3.98E-021P04049RAF1More
Lenvatinibhsa05160Hepatitis C1.99E-021P04049RAF1More
Lenvatinibhsa05161Hepatitis B1.99E-021P04049RAF1More
Lenvatinibhsa05163Human cytomegalovirus infection3.15E-039P04049, P25963, P62873, P63218, P50151, P0DP23, Q14344, P30101, P01568RAF1, NFKBIA, GNB1, GNG5, GNG10, CALM1, GNA13, PDIA3, IFNA21More
Lenvatinibhsa05164Influenza A3.65E-021P04049RAF1More
Lenvatinibhsa05167Kaposi sarcoma-associated herpesvirus infection2.04E-0511P01568, P42224, P25963, P62873, P63218, P50151, P19174, P04049, P07948, P04141, P0DP23IFNA21, STAT1, NFKBIA, GNB1, GNG5, GNG10, PLCG1, RAF1, LYN, CSF2, CALM1More
Lenvatinibhsa05168Herpes simplex virus 1 infection3.79E-029P25963, P01568, P42224, Q07955, Q01130, Q13243, P30101, Q13398, O75820NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, PDIA3, ZNF211, ZNF189More
Lenvatinibhsa05169Epstein-Barr virus infection4.84E-0310P13765, P01106, Q13547, O00463, P07948, Q13761, P24522, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, LYN, RUNX3, GADD45A, CD3E, CD3G, CD247More
Lenvatinibhsa05170Human immunodeficiency virus 1 infection2.44E-039P04049, P62873, P63218, P50151, P0DP23, P30101, P01568, P25963, P19174RAF1, GNB1, GNG5, GNG10, CALM1, PDIA3, IFNA21, NFKBIA, PLCG1More
Lenvatinibhsa05200Pathways in cancer1.99E-0315P08238, P42224, P25963, P19174, P43246, P84022, P20585, P62873, P63218, P50151, Q14344, O75293, P0DP23, P01568, P14784HSP90AB1, STAT1, NFKBIA, PLCG1, MSH2, SMAD3, MSH3, GNB1, GNG5, GNG10, GNA13, GADD45B, CALM1, IFNA21, IL2RBMore
Lenvatinibhsa05202Transcriptional misregulation in cancer8.91E-0418Q12778, Q13315, P17844, P14780, P27930, Q16548, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, ATM, DDX5, MMP9, IL1R2, BCL2A1, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Lenvatinibhsa05205Proteoglycans in cancer3.48E-021P04049RAF1More
Lenvatinibhsa05206MicroRNAs in cancer3.15E-021P04049RAF1More
Lenvatinibhsa05210Colorectal cancer1.66E-021P04049RAF1More
Lenvatinibhsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Lenvatinibhsa05212Pancreatic cancer9.52E-034P04049, P42224, P84022, O75293RAF1, STAT1, SMAD3, GADD45BMore
Lenvatinibhsa05213Endometrial cancer9.95E-031P04049RAF1More
Lenvatinibhsa05214Glioma7.45E-034P0DP23, P04049, P19174, O75293CALM1, RAF1, PLCG1, GADD45BMore
Lenvatinibhsa05215Prostate cancer1.33E-021P04049RAF1More
Lenvatinibhsa05217Basal cell carcinoma3.50E-024Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Lenvatinibhsa05218Melanoma6.63E-031P04049RAF1More
Lenvatinibhsa05219Bladder cancer4.98E-031P04049RAF1More
Lenvatinibhsa05220Chronic myeloid leukemia9.95E-031P04049RAF1More
Lenvatinibhsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Lenvatinibhsa05223Non-small cell lung cancer6.63E-031P04049RAF1More
Lenvatinibhsa05224Breast cancer1.49E-021P04049RAF1More
Lenvatinibhsa05225Hepatocellular carcinoma1.33E-021P04049RAF1More
Lenvatinibhsa05226Gastric cancer8.29E-031P04049RAF1More
Lenvatinibhsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Lenvatinibhsa05231Choline metabolism in cancer1.33E-021P04049RAF1More
Lenvatinibhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer3.98E-0512O95267, P07766, P20963, P09693, P06239, P04049, P23458, O60603, P10747, Q04759, Q16539, P01730RASGRP1, CD3E, CD247, CD3G, LCK, RAF1, JAK1, TLR2, CD28, PRKCQ, MAPK14, CD4More
Lenvatinibhsa05321Inflammatory bowel disease8.20E-057O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1BMore
Lenvatinibhsa05323Rheumatoid arthritis1.60E-024P13765, P10747, P09341, O60603HLA-DOB, CD28, CXCL1, TLR2More
Lenvatinibhsa05332Graft-versus-host disease3.63E-044P13765, P10747, P26715, Q13241HLA-DOB, CD28, KLRC1, KLRD1More
Lenvatinibhsa05340Primary immunodeficiency2.19E-024P01730, P01732, P07766, P06239CD4, CD8A, CD3E, LCKMore
Lenvatinibhsa05410Hypertrophic cardiomyopathy2.03E-022P26012, P09493ITGB8, TPM1More
Lenvatinibhsa05412Arrhythmogenic right ventricular cardiomyopathy4.48E-021P54284CACNB3More
Lenvatinibhsa05414Dilated cardiomyopathy4.55E-022P54284, P26678CACNB3, PLNMore

Community members of Lenvatinib (SDC: 4.85)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
Q02763TEKAngiopoietinNone1 receptorPredicted00.32060.62360.43041.8379
P08238HSP90AB1Heat shock protein HSP 90NonebetaPredicted00.06110.52080.7411.8131
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P07948LYNTyrosineNoneprotein kinase LynPredicted00.0910.53190.6061.7154
P42330AKR1C3AldoNoneketo reductase family 1 member C3Predicted00.40170.83480.17482.0453
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
Q9Y6K0CEPT1Choline/ethanolaminephosphotransferase 1Predicted00.22610.01630.15910.3047
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)