PharmaCoNets of Leflunomide (SPCN: 79.64 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Leflunomidehsa00052Galactose metabolism4.27E-022P06280, O43451GLA, MGAMMore
Leflunomidehsa00071Fatty acid degradation3.50E-024O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Leflunomidehsa00220Arginine biosynthesis1.43E-022P05089, P49448ARG1, GLUD2More
Leflunomidehsa00500Starch and sucrose metabolism6.17E-033O43451, P46976, P06737MGAM, GYG1, PYGLMore
Leflunomidehsa00512Mucin type O-glycan biosynthesis3.78E-022O95395, Q8N4A0GCNT3, GALNT4More
Leflunomidehsa00533Glycosaminoglycan biosynthesis - keratan sulfate1.91E-021Q9NY97B3GNT2More
Leflunomidehsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Leflunomidehsa00630Glyoxylate and dicarboxylate metabolism5.34E-032P40925, P15104MDH1, GLULMore
Leflunomidehsa00730Thiamine metabolism2.27E-022P05186, P24666ALPL, ACP1More
Leflunomidehsa00830Retinol metabolism2.20E-024P00325, P11766, Q9BPW9, O75911ADH1B, ADH5, DHRS9, DHRS3More
Leflunomidehsa00970Aminoacyl-tRNA biosynthesis3.78E-022O95363, Q15046FARS2, KARSMore
Leflunomidehsa012102-Oxocarboxylic acid metabolism1.91E-021P50213IDH3AMore
Leflunomidehsa01523Antifolate resistance3.80E-022Q92820, P04818GGH, TYMSMore
Leflunomidehsa03013RNA transport2.99E-024P38919, P37198, P35658, P55884EIF4A3, NUP62, NUP214, EIF3BMore
Leflunomidehsa03020RNA polymerase3.00E-023P30876, P24928, P62487POLR2B, POLR2A, POLR2GMore
Leflunomidehsa03040Spliceosome2.92E-0614Q14562, O43143, O60508, P08579, P26368, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Leflunomidehsa03060Protein export4.42E-022P37108, Q15005SRP14, SPCS2More
Leflunomidehsa03320PPAR signaling pathway4.33E-022Q6PCB7, Q9UNU6SLC27A1, CYP8B1More
Leflunomidehsa04014Ras signaling pathway2.36E-028P42338, P20827, P49767, Q13009, Q7LDG7, P63218, P50151, P19174PIK3CB, EFNA1, VEGFC, TIAM1, RASGRP2, GNG5, GNG10, PLCG1More
Leflunomidehsa04015Rap1 signaling pathway1.79E-028P20827, P49767, Q96FS4, P11215, Q13009, Q7LDG7, P42338, P19174EFNA1, VEGFC, SIPA1, ITGAM, TIAM1, RASGRP2, PIK3CB, PLCG1More
Leflunomidehsa04061Viral protein interaction with cytokine and cytokine receptor4.48E-025P09341, P19875, P25024, P25025, P14784CXCL1, CXCL2, CXCR1, CXCR2, IL2RBMore
Leflunomidehsa04062Chemokine signaling pathway5.65E-0414P25024, P25025, P09341, P19875, P09769, P07948, P42338, P19174, P63218, P50151, P43250, Q7LDG7, Q13009, Q8WYR1CXCR1, CXCR2, CXCL1, CXCL2, FGR, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, RASGRP2, TIAM1, PIK3R5More
Leflunomidehsa04064NF-kappa B signaling pathway1.42E-0620P10415, O00463, P14778, P01584, P01375, P19174, Q04759, Q9UDY8, Q13077, Q16548, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9NQC7BCL2, TRAF5, IL1R1, IL1B, TNF, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, CYLDMore
Leflunomidehsa04071Sphingolipid signaling pathway6.92E-046P21453, Q9H228, P01375, Q13362, Q9BX95, P10415S1PR1, EDG8, TNF, PPP2R5C, SGPP1, BCL2More
Leflunomidehsa04072Phospholipase D signaling pathway4.48E-025P42338, P43657, P25024, P25025, P19174PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1More
Leflunomidehsa04080Neuroactive ligand-receptor interaction1.00E-027P08311, Q15722, P21453, Q9H228, O00398, P21730, P07550CTSG, LTB4R, S1PR1, EDG8, P2RY10, C5AR1, ADRB2More
Leflunomidehsa04110Cell cycle6.80E-036P06493, O75293, P30304, P33981, P42773, P01106CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYCMore
Leflunomidehsa04114Oocyte meiosis6.23E-035Q9Y6D9, P51812, Q02750, P16298, Q17RY0MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Leflunomidehsa04140Autophagy - animal3.15E-035P22694, Q14643, P10415, Q9H1Y0, Q04759PRKACB, ITPR1, BCL2, ATG5, PRKCQMore
Leflunomidehsa04142Lysosome1.46E-027P06865, P22304, P38571, Q13510, P07602, Q9NRA2, P61916HEXA, IDS, LIPA, ASAH1, PSAP, SLC17A5, NPC2More
Leflunomidehsa04144Endocytosis1.67E-028P0DMV8, Q9H444, O75351, P62491, Q96B97, Q15438, Q14161, Q9UMY4HSPA1A, CHMP4B, VPS4B, RAB11A, SH3KBP1, PSCD1, GIT2, SNX12More
Leflunomidehsa04145Phagosome4.48E-025Q15080, P05164, O60603, P35443, P13765NCF4, MPO, TLR2, THBS4, HLA-DOBMore
Leflunomidehsa04151PI3K-Akt signaling pathway3.70E-0212P42338, P43657, P20827, P49767, P08238, Q8WYR1, P63218, P50151, O15335, Q13751, P14784, P30281PIK3CB, P2RY5, EFNA1, VEGFC, HSP90AB1, PIK3R5, GNG5, GNG10, CHAD, LAMB3, IL2RB, CCND3More
Leflunomidehsa04210Apoptosis3.44E-027Q13315, P10415, O76075, P24522, Q16548, P43234, Q14643ATM, BCL2, DFFB, GADD45A, BCL2A1, CTSO, ITPR1More
Leflunomidehsa04213Longevity regulating pathway - multiple species2.70E-037P42338, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547PIK3CB, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Leflunomidehsa04218Cellular senescence4.79E-024P01106, O75293, P30304, P06493MYC, GADD45B, CDC25A, CDK1More
Leflunomidehsa04270Vascular smooth muscle contraction6.96E-036P0DP23, Q08828, P51828, P35579, P35749, P35318CALM1, ADCY1, ADCY7, MYH9, MYH11, ADMMore
Leflunomidehsa04330Notch signaling pathway2.77E-022Q92542, P49768NCSTN, PSEN1More
Leflunomidehsa04340Hedgehog signaling pathway3.09E-023P22694, Q13635, P10415PRKACB, PTCH1, BCL2More
Leflunomidehsa04360Axon guidance4.04E-026P16333, P20827, O95631, P42338, P07332, P19174NCK1, EFNA1, NTN1, PIK3CB, FES, PLCG1More
Leflunomidehsa04370VEGF signaling pathway3.06E-033P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Leflunomidehsa04371Apelin signaling pathway1.00E-027P63218, P50151, Q8WYR1, Q14814, Q14344, Q13485, P84022GNG5, GNG10, PIK3R5, MEF2D, GNA13, SMAD4, SMAD3More
Leflunomidehsa04380Osteoclast differentiation9.58E-0513Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Leflunomidehsa04390Hippo signaling pathway4.35E-022P63261, O15105ACTG1, SMAD7More
Leflunomidehsa04530Tight junction4.35E-022P63261, Q92974ACTG1, ARHGEF2More
Leflunomidehsa04550Signaling pathways regulating pluripotency of stem cells4.73E-023Q13873, Q02750, Q86SE9BMPR2, MAP2K1, PCGF5More
Leflunomidehsa04612Antigen processing and presentation1.42E-048P13765, P48382, P26715, P26717, Q07444, Q13241, P01732, P01375HLA-DOB, RFX5, KLRC1, KLRC2, KLRC3, KLRD1, CD8A, TNFMore
Leflunomidehsa04613Neutrophil extracellular trap formation5.63E-0417O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P0C0S5, Q6FI13, Q15080, P20160, P08311, P49913, O75015, P21730, P21462, O43315, Q16539TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AFZ, H2AC18; H2AC19, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Leflunomidehsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Leflunomidehsa04623Cytosolic DNA-sensing pathway1.65E-022P01584, Q8NHW4IL1B, CCL4L2More
Leflunomidehsa04625C-type lectin receptor signaling pathway9.91E-049Q9ULY5, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P0DP24, Q16539CLEC4E, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, CALM2, MAPK14More
Leflunomidehsa04640Hematopoietic cell lineage5.42E-0516P13612, P21926, P14778, P27930, P11215, P15144, P11836, P25063, P07766, P09693, P01732, P01730, P09564, P13765, P01375, P01584ITGA4, CD9, IL1R1, IL1R2, ITGAM, ANPEP, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD7, HLA-DOB, TNF, IL1BMore
Leflunomidehsa04650Natural killer cell mediated cytotoxicity9.83E-0917P16298, P50591, P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q02750, Q13241, P26718, O14931, O75015, P26717, Q07444, P26715PPP3CB, TNFSF10, PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KLRC1More
Leflunomidehsa04657IL-17 signaling pathway9.91E-048O00463, Q16539, P49841, P09341, P14780, P80188, P01375, P01584TRAF5, MAPK14, GSK3B, CXCL1, MMP9, LCN2, TNF, IL1BMore
Leflunomidehsa04658Th1 and Th2 cell differentiation1.00E-1114Q04759, P07766, P20963, P09693, Q16539, P19174, P06239, Q14765, P23771, Q9UL17, P14784, P13765, P23458, Q13761PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, LCK, STAT4, GATA3, TBX21, IL2RB, HLA-DOB, JAK1, RUNX3More
Leflunomidehsa04659Th17 cell differentiation7.89E-0917Q04759, Q16539, P19174, P06239, P14784, P13765, P14778, Q9UL17, P23771, P84022, Q13485, P01584, P08238, P07766, P09693, P20963, P23458PRKCQ, MAPK14, PLCG1, LCK, IL2RB, HLA-DOB, IL1R1, TBX21, GATA3, SMAD3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Leflunomidehsa04660T cell receptor signaling pathway8.76E-1016P01375, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, P07766, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, CD3E, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Leflunomidehsa04662B cell receptor signaling pathway1.17E-045P42338, P60033, P07948, P21854, Q8N149PIK3CB, CD81, LYN, CD72, LILRA2More
Leflunomidehsa04664Fc epsilon RI signaling pathway1.62E-047P01375, Q16539, P42338, Q9UQC2, P07948, P19174, P09917TNF, MAPK14, PIK3CB, GAB2, LYN, PLCG1, ALOX5More
Leflunomidehsa04668TNF signaling pathway2.21E-025P01375, O00463, Q16539, P20749, P14780TNF, TRAF5, MAPK14, BCL3, MMP9More
Leflunomidehsa04672Intestinal immune network for IgA production1.66E-023P10747, P13765, P13612CD28, HLA-DOB, ITGA4More
Leflunomidehsa04720Long-term potentiation2.85E-023P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Leflunomidehsa04724Glutamatergic synapse5.94E-034O15399, P63218, P50151, P15104GRIN2D, GNG5, GNG10, GLULMore
Leflunomidehsa04725Cholinergic synapse4.10E-023P63218, P50151, P42338GNG5, GNG10, PIK3CBMore
Leflunomidehsa04727GABAergic synapse1.63E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
Leflunomidehsa04750Inflammatory mediator regulation of TRP channels3.66E-0513P14778, P01584, Q08828, P51828, P22694, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2, CALM1More
Leflunomidehsa04912GnRH signaling pathway4.33E-026P51828, Q16539, Q9Y6R4, Q14643, P0DP24, P22694ADCY7, MAPK14, MAP3K4, ITPR1, CALM2, PRKACBMore
Leflunomidehsa04914Progesterone-mediated oocyte maturation1.00E-024Q17RY0, Q9Y6D9, P51812, Q02750CPEB4, MAD1L1, RPS6KA3, MAP2K1More
Leflunomidehsa04915Estrogen signaling pathway3.17E-025Q08828, P51828, P0DMV8, P0DP23, Q15788ADCY1, ADCY7, HSPA1A, CALM1, NCOA1More
Leflunomidehsa04922Glucagon signaling pathway4.23E-024P22694, P06737, Q12778, Q14643PRKACB, PYGL, FOXO1, ITPR1More
Leflunomidehsa04923Regulation of lipolysis in adipocytes2.24E-023P07550, P42338, Q9Y4H2ADRB2, PIK3CB, IRS2More
Leflunomidehsa04924Renin secretion8.55E-043P22694, P07550, Q14643PRKACB, ADRB2, ITPR1More
Leflunomidehsa04926Relaxin signaling pathway5.70E-035P42338, P63218, P50151, P49767, P49407PIK3CB, GNG5, GNG10, VEGFC, ARRB1More
Leflunomidehsa04927Cortisol synthesis and secretion1.66E-023Q14643, P18848, P22694ITPR1, ATF4, PRKACBMore
Leflunomidehsa04928Parathyroid hormone synthesis, secretion and action4.23E-024Q14643, P22694, P23771, P10415ITPR1, PRKACB, GATA3, BCL2More
Leflunomidehsa04929GnRH secretion4.62E-022P42338, P49407PIK3CB, ARRB1More
Leflunomidehsa04932Non-alcoholic fatty liver disease1.39E-026O43521, O75460, P01584, P13073, P12074, O95298BCL2L11, ERN1, IL1B, COX4I1, COX6A1, NDUFC2More
Leflunomidehsa04933AGE-RAGE signaling pathway in diabetic complications3.21E-025P84022, Q13485, P42338, P49767, P19174SMAD3, SMAD4, PIK3CB, VEGFC, PLCG1More
Leflunomidehsa04940Type I diabetes mellitus3.64E-023P10747, P13765, P01375CD28, HLA-DOB, TNFMore
Leflunomidehsa04970Salivary secretion5.33E-037P07550, Q08828, P51828, P22694, Q14643, P0DP23, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, CALM1, CAMPMore
Leflunomidehsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Leflunomidehsa04976Bile secretion4.78E-023Q08828, P51828, Q14032ADCY1, ADCY7, BAATMore
Leflunomidehsa05016Huntington disease2.46E-029O95298, P13073, P12074, P24928, P30876, P62487, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, ERN1, PSMB4, PSMD12More
Leflunomidehsa05100Bacterial invasion of epithelial cells2.85E-023Q14141, Q05397, Q96JJ3SEPT6, PTK2, ELMO2More
Leflunomidehsa05120Epithelial cell signaling in Helicobacter pylori infection2.78E-035P09341, P19875, P19174, P25024, P25025CXCL1, CXCL2, PLCG1, CXCR1, CXCR2More
Leflunomidehsa05134Legionellosis8.80E-047P01584, Q9NR31, P11215, P0DMV8, P11142, P09341, P19875IL1B, SAR1A, ITGAM, HSPA1A, HSPA8, CXCL1, CXCL2More
Leflunomidehsa05135Yersinia infection3.29E-024Q05397, P51812, Q02750, Q96JJ3PTK2, RPS6KA3, MAP2K1, ELMO2More
Leflunomidehsa05140Leishmaniasis2.29E-029P13612, O75015, P23458, P13765, O60603, P01375, P01584, Q16539, Q15080ITGA4, FCGR3B, JAK1, HLA-DOB, TLR2, TNF, IL1B, MAPK14, NCF4More
Leflunomidehsa05144Malaria3.04E-036P60033, O60603, P01375, P35443, P01584, P26718CD81, TLR2, TNF, THBS4, IL1B, KLRK1More
Leflunomidehsa05146Amoebiasis7.88E-0713P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, PRKACB, ACTN1, CTSGMore
Leflunomidehsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Leflunomidehsa05163Human cytomegalovirus infection2.22E-0313P01375, P0DP23, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, O00463TNF, CALM1, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, TRAF5More
Leflunomidehsa05169Epstein-Barr virus infection3.72E-026Q13547, P42338, P07948, Q13761, O75293, P07766HDAC1, PIK3CB, LYN, RUNX3, GADD45B, CD3EMore
Leflunomidehsa05200Pathways in cancer9.46E-0317Q13751, P42338, P08238, P19174, P43246, P84022, Q13485, Q13547, P30281, P49767, P43657, P63218, P50151, Q14344, Q7LDG7, O75293, P14784LAMB3, PIK3CB, HSP90AB1, PLCG1, MSH2, SMAD3, SMAD4, HDAC1, CCND3, VEGFC, P2RY5, GNG5, GNG10, GNA13, RASGRP2, GADD45B, IL2RBMore
Leflunomidehsa05202Transcriptional misregulation in cancer1.06E-0419Q12778, Q13315, P17844, P14780, P27930, Q15744, Q16548, Q13077, O15550, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, ATM, DDX5, MMP9, IL1R2, CEBPE, BCL2A1, TRAF1, UTX, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Leflunomidehsa05212Pancreatic cancer3.94E-024P42338, P84022, Q13485, O75293PIK3CB, SMAD3, SMAD4, GADD45BMore
Leflunomidehsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
Leflunomidehsa05217Basal cell carcinoma3.50E-024Q13635, P49841, Q9UJU2, P24522PTCH1, GSK3B, LEF1, GADD45AMore
Leflunomidehsa05220Chronic myeloid leukemia2.16E-025Q13547, Q13485, P84022, P42338, O75293HDAC1, SMAD4, SMAD3, PIK3CB, GADD45BMore
Leflunomidehsa05223Non-small cell lung cancer1.39E-023P10826, Q9HC35, O75293RARB, EML4, GADD45BMore
Leflunomidehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer2.76E-0714P42338, O95267, P19174, P07766, P20963, P09693, P06239, P23458, O60603, P10747, Q04759, Q16539, Q9HC35, P01730PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, JAK1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Leflunomidehsa05310Asthma1.66E-023P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Leflunomidehsa05321Inflammatory bowel disease4.04E-077O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1BMore
Leflunomidehsa05322Systemic lupus erythematosus1.57E-024P08311, P62807, Q16778, P12814CTSG, HIST1H2BC, HIST2H2BE, ACTN1More
Leflunomidehsa05323Rheumatoid arthritis6.71E-045P01375, P13765, P10747, P09341, O60603TNF, HLA-DOB, CD28, CXCL1, TLR2More
Leflunomidehsa05332Graft-versus-host disease1.71E-055P13765, P10747, P01375, P26715, Q13241HLA-DOB, CD28, TNF, KLRC1, KLRD1More
Leflunomidehsa05340Primary immunodeficiency1.28E-034P01730, P11912, P07766, P06239CD4, CD79A, CD3E, LCKMore
Leflunomidehsa05418Fluid shear stress and atherosclerosis1.08E-037Q16539, Q14145, P10599, P14780, P01375, P14778, P27930MAPK14, KEAP1, TXN, MMP9, TNF, IL1R1, IL1R2More

Community members of Leflunomide (SDC: 6.14)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
Q9UM07PADI4ProteinNonearginine deiminase typeNone4Predicted10.14880.27780.42671.0567
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P42338PIK3CBPhosphatidylinositol 4,5Nonebisphosphate 3Nonekinase catalytic subunit beta isoformPredicted10.04470.941612.9055
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
P49768PSEN1PresenilinNone1Predicted10.26770.65990.33081.7845
O14684PTGESProstaglandin E synthasePredicted10.45310.63580.15651.6547
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P00352ALDH1A1Aldehyde dehydrogenase 1A1Predicted00.32080.29250.15430.8998
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
P42330AKR1C3AldoNoneketo reductase family 1 member C3Predicted00.40170.83480.17482.0453
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)