PharmaCoNets of Lauric-acid (SPCN: 14.41 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Lauric-acidhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Lauric-acidhsa00071Fatty acid degradation4.87E-032P11310, P28332ACADM, ADH6More
Lauric-acidhsa00520Amino sugar and nucleotide sugar metabolism7.87E-033Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Lauric-acidhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Lauric-acidhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series4.30E-032P06865, O75752HEXA, B3GALNT1More
Lauric-acidhsa01200Carbon metabolism4.06E-025P37837, O14521, P50213, P60891, Q02252TALDO1, SDHD, IDH3A, PRPS1, ALDH6A1More
Lauric-acidhsa01522Endocrine resistance3.67E-025P14780, P22694, Q9UM47, P46527, P10415MMP9, PRKACB, NOTCH3, CDKN1B, BCL2More
Lauric-acidhsa01523Antifolate resistance2.24E-023P41439, P41440, P01375FOLR3, SLC19A1, TNFMore
Lauric-acidhsa02010ABC transporters4.93E-021Q8IZY2ABCA7More
Lauric-acidhsa03010Ribosome1.86E-022P46777, P50914RPL5, RPL14More
Lauric-acidhsa03013RNA transport6.87E-0311P52298, Q09161, O14893, P61326, P37198, Q7Z3B4, P35658, Q14152, O75822, Q9Y6A5, Q06787NCBP2, NCBP1, GEMIN2, MAGOH, NUP62, NUP54, NUP214, EIF3A, EIF3J, TACC3, FMR1More
Lauric-acidhsa03015mRNA surveillance pathway3.71E-026O43148, Q13362, O94913, Q12996, Q09161, P52298RNMT, PPP2R5C, PCF11, CSTF3, NCBP1, NCBP2More
Lauric-acidhsa03020RNA polymerase3.00E-023P30876, P24928, P62487POLR2B, POLR2A, POLR2GMore
Lauric-acidhsa03060Protein export4.42E-022P37108, Q15005SRP14, SPCS2More
Lauric-acidhsa03320PPAR signaling pathway3.78E-022Q6PCB7, Q9UNU6SLC27A1, CYP8B1More
Lauric-acidhsa04071Sphingolipid signaling pathway1.94E-026Q9H228, P01375, Q13362, Q9BX95, P10415, Q9UQC2EDG8, TNF, PPP2R5C, SGPP1, BCL2, GAB2More
Lauric-acidhsa04114Oocyte meiosis4.51E-035Q9Y6D9, P51812, Q02750, P16298, Q17RY0MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4More
Lauric-acidhsa04137Mitophagy - animal3.24E-024Q96CV9, Q9H1Y0, P18848, O43524OPTN, ATG5, ATF4, FOXO3More
Lauric-acidhsa04141Protein processing in endoplasmic reticulum2.48E-024P30101, P60604, P08238, Q9H173PDIA3, UBE2G2, HSP90AB1, SIL1More
Lauric-acidhsa04142Lysosome1.46E-027P06865, P38571, Q13510, P07602, P61916, Q04900, Q9Y227HEXA, LIPA, ASAH1, PSAP, NPC2, CD164, ENTPD4More
Lauric-acidhsa04144Endocytosis1.38E-0310P0DMV8, Q9H444, O75351, P62491, P42566, Q15438, Q14161, Q96QK1, Q9UMY4, Q9UNH7HSPA1A, CHMP4B, VPS4B, RAB11A, EPS15, PSCD1, GIT2, VPS35, SNX12, SNX6More
Lauric-acidhsa04217Necroptosis3.99E-026P23458, Q9NQC7, P01584, Q9BTM1, Q9H444, O75351JAK1, CYLD, IL1B, H2AFJ, CHMP4B, VPS4BMore
Lauric-acidhsa04260Cardiac muscle contraction4.78E-023P67936, P13073, P12074TPM4, COX4I1, COX6A1More
Lauric-acidhsa04340Hedgehog signaling pathway1.80E-024P49841, P22694, Q13635, P10415GSK3B, PRKACB, PTCH1, BCL2More
Lauric-acidhsa04370VEGF signaling pathway2.47E-033P16298, Q05397, Q02750PPP3CB, PTK2, MAP2K1More
Lauric-acidhsa04514Cell adhesion molecules4.32E-023P13612, P11215, P01730ITGA4, ITGAM, CD4More
Lauric-acidhsa04610Complement and coagulation cascades4.02E-044P0C0L4, P12259, P20023, P11215C4A, F5, CR2, ITGAMMore
Lauric-acidhsa04613Neutrophil extracellular trap formation6.75E-0415P17252, O60603, P05164, P08246, Q9UM07, Q92769, Q6FI13, P14598, Q15080, P49913, O75015, P21730, P21462, O43315, Q16539PRKCA, TLR2, MPO, ELA2, PADI4, HDAC2, H2AC18; H2AC19, NCF1, NCF4, CAMP, FCGR3B, C5AR1, FPR1, AQP9, MAPK14More
Lauric-acidhsa04621NOD-like receptor signaling pathway7.61E-0310P25963, Q9H1Y0, O00463, P10415, Q05823, P01375, P49913, P59665, P59666, P12838NFKBIA, ATG5, TRAF5, BCL2, RNASEL, TNF, CAMP, DEFA1; DEFA1B, DEFA3, DEFA4More
Lauric-acidhsa04640Hematopoietic cell lineage1.01E-025P13612, P11215, P20023, P01730, P04141ITGA4, ITGAM, CR2, CD4, CSF2More
Lauric-acidhsa04650Natural killer cell mediated cytotoxicity2.87E-039P16298, P50591, P01375, Q02750, Q13241, P26718, O75015, P26717, P26715PPP3CB, TNFSF10, TNF, MAP2K1, KLRD1, KLRK1, FCGR3B, KLRC2, KLRC1More
Lauric-acidhsa04657IL-17 signaling pathway1.53E-026P25963, O00463, P14780, P80188, P01375, P06702NFKBIA, TRAF5, MMP9, LCN2, TNF, S100A9More
Lauric-acidhsa04662B cell receptor signaling pathway3.54E-023P25963, P20023, P07948NFKBIA, CR2, LYNMore
Lauric-acidhsa04664Fc epsilon RI signaling pathway1.23E-023P04141, P07948, P09917CSF2, LYN, ALOX5More
Lauric-acidhsa04710Circadian rhythm1.67E-022Q16526, Q9Y478CRY1, PRKAB1More
Lauric-acidhsa04720Long-term potentiation2.35E-023P16298, P51812, Q02750PPP3CB, RPS6KA3, MAP2K1More
Lauric-acidhsa04912GnRH signaling pathway3.39E-024P17252, Q16539, Q9Y6R4, Q14643PRKCA, MAPK14, MAP3K4, ITPR1More
Lauric-acidhsa04914Progesterone-mediated oocyte maturation7.70E-034Q17RY0, Q9Y6D9, P51812, Q02750CPEB4, MAD1L1, RPS6KA3, MAP2K1More
Lauric-acidhsa04919Thyroid hormone signaling pathway4.77E-021O60244MED14More
Lauric-acidhsa04920Adipocytokine signaling pathway4.31E-022Q9Y478, Q96RR4PRKAB1, CAMKK2More
Lauric-acidhsa04924Renin secretion3.64E-023P22694, P07550, Q14643PRKACB, ADRB2, ITPR1More
Lauric-acidhsa04964Proximal tubule bicarbonate reclamation4.93E-021P00918CA2More
Lauric-acidhsa04966Collecting duct acid secretion4.93E-021P00918CA2More
Lauric-acidhsa04972Pancreatic secretion3.86E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Lauric-acidhsa05016Huntington disease2.46E-029O95298, P13073, P12074, P24928, P30876, P62487, O75460, P28070, O00232NDUFC2, COX4I1, COX6A1, POLR2A, POLR2B, POLR2G, ERN1, PSMB4, PSMD12More
Lauric-acidhsa05133Pertussis4.20E-021P0C0L4C4AMore
Lauric-acidhsa05134Legionellosis2.82E-023P01584, Q9NR31, P0DMV8IL1B, SAR1A, HSPA1AMore
Lauric-acidhsa05135Yersinia infection2.58E-024Q05397, P51812, Q02750, Q96JJ3PTK2, RPS6KA3, MAP2K1, ELMO2More
Lauric-acidhsa05140Leishmaniasis2.04E-027O75015, P14598, O60603, P25963, P01375, P29350, Q15080FCGR3B, NCF1, TLR2, NFKBIA, TNF, PTPN6, NCF4More
Lauric-acidhsa05143African trypanosomiasis1.31E-022P69905, P68871HBA2, HBBMore
Lauric-acidhsa05144Malaria6.79E-036P69905, P68871, O60603, P01375, P35443, P26718HBA2, HBB, TLR2, TNF, THBS4, KLRK1More
Lauric-acidhsa05150Staphylococcus aureus infection3.71E-026P21462, O75015, P59665, P59666, P12838, P49913FPR1, FCGR3B, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Lauric-acidhsa05152Tuberculosis3.04E-029Q13488, O75015, P48382, P25208, O60603, P01375, P10415, P49913, Q9UDY8TCIRG1, FCGR3B, RFX5, NFYB, TLR2, TNF, BCL2, CAMP, MALT1More
Lauric-acidhsa05167Kaposi sarcoma-associated herpesvirus infection3.33E-036P25963, P50151, O15123, P07948, P01106, P04141NFKBIA, GNG10, ANGPT2, LYN, MYC, CSF2More
Lauric-acidhsa05169Epstein-Barr virus infection4.73E-025P20023, P01106, P25963, P07948, P30101CR2, MYC, NFKBIA, LYN, PDIA3More
Lauric-acidhsa05170Human immunodeficiency virus 1 infection4.37E-024Q02750, P62879, P16298, Q05397MAP2K1, GNB2, PPP3CB, PTK2More
Lauric-acidhsa05202Transcriptional misregulation in cancer8.78E-0310Q13315, P14780, P46527, P35226, O60583, P05164, P59665, P59666, P12838, P08246ATM, MMP9, CDKN1B, BMI1, CCNT2, MPO, DEFA1; DEFA1B, DEFA3, DEFA4, ELA2More
Lauric-acidhsa05203Viral carcinogenesis4.73E-024P07948, P25963, P62807, Q93079LYN, NFKBIA, HIST1H2BC, H2BC9More
Lauric-acidhsa05221Acute myeloid leukemia1.68E-023P01106, P11215, P04141MYC, ITGAM, CSF2More
Lauric-acidhsa05222Small cell lung cancer4.26E-026P10826, Q13489, P10415, Q13077, O00463, P24522RARB, BIRC3, BCL2, TRAF1, TRAF5, GADD45AMore
Lauric-acidhsa05321Inflammatory bowel disease4.92E-024O60603, P01375, Q14765, Q9UL17TLR2, TNF, STAT4, TBX21More
Lauric-acidhsa05332Graft-versus-host disease1.48E-034P10747, P01375, P26715, Q13241CD28, TNF, KLRC1, KLRD1More
Lauric-acidhsa05412Arrhythmogenic right ventricular cardiomyopathy4.93E-021P54284CACNB3More
Lauric-acidhsa05415Diabetic cardiomyopathy3.19E-027P17252, P14598, Q15080, Q16718, O14521, Q16539, P14780PRKCA, NCF1, NCF4, NDUFA5, SDHD, MAPK14, MMP9More

Community members of Lauric-acid (SDC: 1.76)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)