| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Lamotrigine | hsa00030 | Pentose phosphate pathway | 3.06E-04 | 3 | P60891, P51854, P37837 | PRPS1, TKTL1, TALDO1 | More | | | Lamotrigine | hsa00230 | Purine metabolism | 3.95E-02 | 3 | Q7LG56, P51828, Q9Y227 | RRM2B, ADCY7, ENTPD4 | More | | | Lamotrigine | hsa00240 | Pyrimidine metabolism | 2.84E-02 | 2 | Q7LG56, Q9Y227 | RRM2B, ENTPD4 | More | | | Lamotrigine | hsa00310 | Lysine degradation | 2.59E-02 | 2 | Q96KQ7, P51648 | EHMT2, ALDH3A2 | More | | | Lamotrigine | hsa00380 | Tryptophan metabolism | 4.14E-02 | 1 | Q16613 | AANAT | More | | | Lamotrigine | hsa00500 | Starch and sucrose metabolism | 2.86E-02 | 2 | O43451, P46976 | MGAM, GYG1 | More | | | Lamotrigine | hsa00512 | Mucin type O-glycan biosynthesis | 4.86E-02 | 2 | O95395, Q9NY28 | GCNT3, GALNT8 | More | | | Lamotrigine | hsa00520 | Amino sugar and nucleotide sugar metabolism | 6.13E-03 | 3 | Q16222, Q9Y223, P06865 | UAP1, GNE, HEXA | More | | | Lamotrigine | hsa00603 | Glycosphingolipid biosynthesis - globo and isoglobo series | 3.60E-03 | 2 | P06865, O75752 | HEXA, B3GALNT1 | More | | | Lamotrigine | hsa00630 | Glyoxylate and dicarboxylate metabolism | 9.21E-03 | 2 | P40925, P15104 | MDH1, GLUL | More | | | Lamotrigine | hsa00730 | Thiamine metabolism | 1.75E-04 | 3 | Q9Y6K8, P05186, P24666 | AK5, ALPL, ACP1 | More | | | Lamotrigine | hsa00770 | Pantothenate and CoA biosynthesis | 3.90E-04 | 3 | O95498, O95497, Q9NRN7 | VNN2, VNN1, AASDHPPT | More | | | Lamotrigine | hsa01200 | Carbon metabolism | 4.32E-02 | 3 | P51854, P37837, P60891 | TKTL1, TALDO1, PRPS1 | More | | | Lamotrigine | hsa01230 | Biosynthesis of amino acids | 2.60E-02 | 3 | P51854, P60891, P37837 | TKTL1, PRPS1, TALDO1 | More | | | Lamotrigine | hsa01240 | Biosynthesis of cofactors | 3.34E-02 | 3 | P05186, Q9Y6K8, O75911 | ALPL, AK5, DHRS3 | More | | | Lamotrigine | hsa01524 | Platinum drug resistance | 1.13E-02 | 5 | P10415, Q13489, P78417, P23025, P43246 | BCL2, BIRC3, GSTO1, XPA, MSH2 | More | | | Lamotrigine | hsa02010 | ABC transporters | 4.48E-02 | 1 | Q8IZY2 | ABCA7 | More | | | Lamotrigine | hsa03008 | Ribosome biogenesis in eukaryotes | 4.44E-04 | 7 | Q9NYH9, P19784, P67870, P78345, Q9BVP2, O15381, Q9GZY0 | UTP6, CSNK2A2, CSNK2B, RPP38, GNL3, NVL, NXF2; NXF2B | More | | | Lamotrigine | hsa03013 | RNA transport | 7.94E-03 | 8 | P52298, O14893, P61326, Q7Z3B4, Q14152, O75822, P78345, Q9Y6A5 | NCBP2, GEMIN2, MAGOH, NUP54, EIF3A, EIF3J, RPP38, TACC3 | More | | | Lamotrigine | hsa03040 | Spliceosome | 2.00E-04 | 10 | Q14562, O43143, O60508, Q99633, Q13595, Q07955, Q01130, Q13243, Q9UMS4, P11142 | DHX8, DHX15, CDC40, PRPF18, TRA2A, SFRS1, SFRS2, SFRS5, PRPF19, HSPA8 | More | | | Lamotrigine | hsa03050 | Proteasome | 1.40E-02 | 1 | P55036 | PSMD4 | More | | | Lamotrigine | hsa03060 | Protein export | 1.49E-02 | 2 | P37108, Q15005 | SRP14, SPCS2 | More | | | Lamotrigine | hsa04014 | Ras signaling pathway | 8.66E-03 | 7 | Q9NRA1, Q13009, P0DP23, P62873, P63218, P50151, P19174 | PDGFC, TIAM1, CALM1, GNB1, GNG5, GNG10, PLCG1 | More | | | Lamotrigine | hsa04015 | Rap1 signaling pathway | 1.58E-02 | 6 | P20827, P49767, P63261, P25116, P0DP23, P17252 | EFNA1, VEGFC, ACTG1, F2R, CALM1, PRKCA | More | | | Lamotrigine | hsa04020 | Calcium signaling pathway | 1.16E-03 | 7 | Q16566, P17252, O15399, P25116, P0DP23, P23634, P49767 | CAMK4, PRKCA, GRIN2D, F2R, CALM1, ATP2B4, VEGFC | More | | | Lamotrigine | hsa04024 | cAMP signaling pathway | 3.11E-03 | 8 | P63092, P26678, P0DP23, P23634, P61586, Q16566, O15399, P25116 | GNAS, PLN, CALM1, ATP2B4, RHOA, CAMK4, GRIN2D, F2R | More | | | Lamotrigine | hsa04062 | Chemokine signaling pathway | 1.59E-03 | 9 | P07948, P19174, P62873, P63218, P50151, Q13009, P14598, P42224, P25963 | LYN, PLCG1, GNB1, GNG5, GNG10, TIAM1, NCF1, STAT1, NFKBIA | More | | | Lamotrigine | hsa04064 | NF-kappa B signaling pathway | 4.92E-02 | 6 | P10415, P51617, Q13546, Q9UDY8, Q13077, P24522 | BCL2, IRAK1, RIPK1, MALT1, TRAF1, GADD45A | More | | | Lamotrigine | hsa04070 | Phosphatidylinositol signaling system | 3.02E-03 | 7 | P19174, P0DP23, Q14643, P23743, O14732, P27987, P17252 | PLCG1, CALM1, ITPR1, DGKA, IMPA2, ITPKB, PRKCA | More | | | Lamotrigine | hsa04071 | Sphingolipid signaling pathway | 3.85E-04 | 9 | P17252, P21453, Q9H228, P01375, Q13362, Q16537, Q9BX95, P04637, P10415 | PRKCA, S1PR1, EDG8, TNF, PPP2R5C, PPP2R5E, SGPP1, TP53, BCL2 | More | | | Lamotrigine | hsa04072 | Phospholipase D signaling pathway | 2.75E-02 | 3 | P61586, O14986, P63092 | RHOA, PIP5K1B, GNAS | More | | | Lamotrigine | hsa04080 | Neuroactive ligand-receptor interaction | 1.97E-02 | 5 | P28472, P21453, Q9H228, P21730, P07550 | GABRB3, S1PR1, EDG8, C5AR1, ADRB2 | More | | | Lamotrigine | hsa04114 | Oocyte meiosis | 1.92E-02 | 4 | Q9Y6D9, P51812, Q02750, Q14738 | MAD1L1, RPS6KA3, MAP2K1, PPP2R5D | More | | | Lamotrigine | hsa04120 | Ubiquitin mediated proteolysis | 7.08E-04 | 6 | Q14145, Q13042, Q13191, P62837, Q15751, Q7Z6Z7 | KEAP1, CDC16, CBLB, UBE2D2, HERC1, HUWE1 | More | | | Lamotrigine | hsa04137 | Mitophagy - animal | 2.52E-02 | 2 | P19784, P67870 | CSNK2A2, CSNK2B | More | | | Lamotrigine | hsa04141 | Protein processing in endoplasmic reticulum | 8.60E-03 | 6 | P30101, P60604, P11142, P08238, Q9H173, Q9UNL2 | PDIA3, UBE2G2, HSPA8, HSP90AB1, SIL1, SSR3 | More | | | Lamotrigine | hsa04145 | Phagosome | 3.54E-04 | 9 | P11215, P63261, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, P27824 | ITGAM, ACTG1, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, CANX | More | | | Lamotrigine | hsa04217 | Necroptosis | 2.34E-02 | 4 | P01375, P48023, Q14765, Q99878 | TNF, FASLG, STAT4, H2AC14 | More | | | Lamotrigine | hsa04261 | Adrenergic signaling in cardiomyocytes | 2.85E-03 | 9 | P07550, P22694, P18848, Q13362, Q16537, P0DP23, P17252, P10415, P20020 | ADRB2, PRKACB, ATF4, PPP2R5C, PPP2R5E, CALM1, PRKCA, BCL2, ATP2B1 | More | | | Lamotrigine | hsa04310 | Wnt signaling pathway | 4.17E-03 | 3 | P61586, P19784, P67870 | RHOA, CSNK2A2, CSNK2B | More | | | Lamotrigine | hsa04350 | TGF-beta signaling pathway | 4.88E-02 | 1 | P37173 | TGFBR2 | More | | | Lamotrigine | hsa04371 | Apelin signaling pathway | 7.95E-04 | 7 | P62873, P63218, P50151, Q13370, Q14344, P84022, P0DP23 | GNB1, GNG5, GNG10, PDE3B, GNA13, SMAD3, CALM1 | More | | | Lamotrigine | hsa04390 | Hippo signaling pathway | 1.47E-02 | 5 | P63261, Q13485, Q9UJU2, O43623, Q13489 | ACTG1, SMAD4, LEF1, SNAI2, BIRC3 | More | | | Lamotrigine | hsa04510 | Focal adhesion | 3.86E-03 | 9 | Q15942, O14986, P17252, P61586, Q16363, Q13489, P10415, P49767, P63261 | ZYX, PIP5K1B, PRKCA, RHOA, LAMA4, BIRC3, BCL2, VEGFC, ACTG1 | More | | | Lamotrigine | hsa04520 | Adherens junction | 1.66E-04 | 7 | Q13485, Q9UJU2, O43623, P19784, P67870, P61586, P63261 | SMAD4, LEF1, SNAI2, CSNK2A2, CSNK2B, RHOA, ACTG1 | More | | | Lamotrigine | hsa04540 | Gap junction | 1.30E-03 | 5 | P17252, Q13509, P68371, Q71U36, Q9NRA1 | PRKCA, TUBB3, TUBB2C, TUBA1A, PDGFC | More | | | Lamotrigine | hsa04610 | Complement and coagulation cascades | 1.91E-03 | 1 | P0C0L4 | C4A | More | | | Lamotrigine | hsa04612 | Antigen processing and presentation | 1.07E-03 | 6 | Q14953, P26715, P26717, Q13241, P01732, P01375 | KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNF | More | | | Lamotrigine | hsa04613 | Neutrophil extracellular trap formation | 1.68E-02 | 9 | P17252, O60603, P08246, Q92769, Q6FI13, P33778, P14598, Q15080, P21462 | PRKCA, TLR2, ELA2, HDAC2, H2AC18; H2AC19, H2BC3, NCF1, NCF4, FPR1 | More | | | Lamotrigine | hsa04614 | Renin-angiotensin system | 1.52E-02 | 1 | P50052 | AGTR2 | More | | | Lamotrigine | hsa04621 | NOD-like receptor signaling pathway | 4.31E-02 | 4 | P01375, P59665, P59666, P12838 | TNF, DEFA1; DEFA1B, DEFA3, DEFA4 | More | | | Lamotrigine | hsa04623 | Cytosolic DNA-sensing pathway | 2.59E-02 | 2 | P01568, P25963 | IFNA21, NFKBIA | More | | | Lamotrigine | hsa04640 | Hematopoietic cell lineage | 4.27E-02 | 4 | P08514, P14778, P01730, P13765 | ITGA2B, IL1R1, CD4, HLA-DOB | More | | | Lamotrigine | hsa04650 | Natural killer cell mediated cytotoxicity | 5.05E-04 | 7 | P01375, P20963, Q13241, P26718, P26717, Q14953, P26715 | TNF, CD247, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1 | More | | | Lamotrigine | hsa04657 | IL-17 signaling pathway | 2.41E-02 | 4 | P19875, P14780, P80188, P01375 | CXCL2, MMP9, LCN2, TNF | More | | | Lamotrigine | hsa04659 | Th17 cell differentiation | 8.83E-04 | 10 | P25963, Q16539, P19174, P01730, P42224, P14784, P13765, P14778, P84022, P08238 | NFKBIA, MAPK14, PLCG1, CD4, STAT1, IL2RB, HLA-DOB, IL1R1, SMAD3, HSP90AB1 | More | | | Lamotrigine | hsa04664 | Fc epsilon RI signaling pathway | 6.97E-03 | 4 | P04141, P07948, P19174, P09917 | CSF2, LYN, PLCG1, ALOX5 | More | | | Lamotrigine | hsa04666 | Fc gamma R-mediated phagocytosis | 2.22E-02 | 4 | P49006, P06396, P14598, P17252 | MARCKSL1, GSN, NCF1, PRKCA | More | | | Lamotrigine | hsa04668 | TNF signaling pathway | 3.55E-02 | 4 | P01375, P18848, P19875, P14780 | TNF, ATF4, CXCL2, MMP9 | More | | | Lamotrigine | hsa04713 | Circadian entrainment | 2.79E-03 | 5 | P0DP23, P62873, P63218, P50151, P63092 | CALM1, GNB1, GNG5, GNG10, GNAS | More | | | Lamotrigine | hsa04720 | Long-term potentiation | 3.70E-04 | 5 | P17252, Q16566, P0DP23, O15399, Q14643 | PRKCA, CAMK4, CALM1, GRIN2D, ITPR1 | More | | | Lamotrigine | hsa04722 | Neurotrophin signaling pathway | 3.27E-02 | 3 | P49841, O43524, P48023 | GSK3B, FOXO3, FASLG | More | | | Lamotrigine | hsa04723 | Retrograde endocannabinoid signaling | 4.94E-02 | 2 | P48169, P62873 | GABRA4, GNB1 | More | | | Lamotrigine | hsa04724 | Glutamatergic synapse | 1.45E-03 | 5 | P63092, P62873, P63218, P50151, P15104 | GNAS, GNB1, GNG5, GNG10, GLUL | More | | | Lamotrigine | hsa04726 | Serotonergic synapse | 2.79E-03 | 5 | P63092, P62873, P63218, P50151, P09917 | GNAS, GNB1, GNG5, GNG10, ALOX5 | More | | | Lamotrigine | hsa04727 | GABAergic synapse | 4.18E-03 | 4 | P62873, P63218, P50151, P15104 | GNB1, GNG5, GNG10, GLUL | More | | | Lamotrigine | hsa04730 | Long-term depression | 4.86E-02 | 2 | Q14344, P07948 | GNA13, LYN | More | | | Lamotrigine | hsa04740 | Olfactory transduction | 2.52E-02 | 1 | Q9H255 | OR51E2 | More | | | Lamotrigine | hsa04742 | Taste transduction | 1.01E-02 | 1 | P30939 | HTR1F | More | | | Lamotrigine | hsa04744 | Phototransduction | 9.21E-03 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | | | Lamotrigine | hsa04912 | GnRH signaling pathway | 4.42E-02 | 3 | P17252, Q14643, P0DP23 | PRKCA, ITPR1, CALM1 | More | | | Lamotrigine | hsa04913 | Ovarian steroidogenesis | 2.54E-02 | 2 | P42330, P22694 | AKR1C3, PRKACB | More | | | Lamotrigine | hsa04914 | Progesterone-mediated oocyte maturation | 3.88E-02 | 3 | Q9Y6D9, P51812, Q02750 | MAD1L1, RPS6KA3, MAP2K1 | More | | | Lamotrigine | hsa04916 | Melanogenesis | 3.55E-02 | 3 | P0DP23, Q9UJU2, P17252 | CALM1, LEF1, PRKCA | More | | | Lamotrigine | hsa04918 | Thyroid hormone synthesis | 3.95E-02 | 3 | P51828, P02768, P05543 | ADCY7, ALB, SERPINA7 | More | | | Lamotrigine | hsa04919 | Thyroid hormone signaling pathway | 2.44E-02 | 3 | Q02750, Q15788, P08237 | MAP2K1, NCOA1, PFKM | More | | | Lamotrigine | hsa04921 | Oxytocin signaling pathway | 4.19E-02 | 4 | P0DP23, P17252, Q16566, P63261 | CALM1, PRKCA, CAMK4, ACTG1 | More | | | Lamotrigine | hsa04924 | Renin secretion | 4.04E-02 | 2 | P22694, P07550 | PRKACB, ADRB2 | More | | | Lamotrigine | hsa04925 | Aldosterone synthesis and secretion | 2.90E-04 | 6 | Q14643, P0DP23, P17252, Q16566, P20020, P23634 | ITPR1, CALM1, PRKCA, CAMK4, ATP2B1, ATP2B4 | More | | | Lamotrigine | hsa04926 | Relaxin signaling pathway | 2.41E-02 | 4 | P18848, P22694, P14780, P30679 | ATF4, PRKACB, MMP9, GNA15 | More | | | Lamotrigine | hsa04927 | Cortisol synthesis and secretion | 2.54E-02 | 2 | P18848, P22694 | ATF4, PRKACB | More | | | Lamotrigine | hsa04932 | Non-alcoholic fatty liver disease | 2.74E-02 | 3 | P01375, P49841, P48023 | TNF, GSK3B, FASLG | More | | | Lamotrigine | hsa04933 | AGE-RAGE signaling pathway in diabetic complications | 3.36E-02 | 4 | Q13485, P10415, P49767, P17252 | SMAD4, BCL2, VEGFC, PRKCA | More | | | Lamotrigine | hsa04940 | Type I diabetes mellitus | 6.87E-04 | 2 | P48023, P01375 | FASLG, TNF | More | | | Lamotrigine | hsa04964 | Proximal tubule bicarbonate reclamation | 4.48E-02 | 1 | P00918 | CA2 | More | | | Lamotrigine | hsa04966 | Collecting duct acid secretion | 2.19E-03 | 3 | P02730, P00918, Q9Y666 | SLC4A1, CA2, SLC12A7 | More | | | Lamotrigine | hsa04970 | Salivary secretion | 4.63E-05 | 8 | P07550, P22694, Q14643, P20020, P23634, P17252, P0DP23, P49913 | ADRB2, PRKACB, ITPR1, ATP2B1, ATP2B4, PRKCA, CALM1, CAMP | More | | | Lamotrigine | hsa04971 | Gastric acid secretion | 4.76E-02 | 3 | P17252, P63261, P0DP23 | PRKCA, ACTG1, CALM1 | More | | | Lamotrigine | hsa04972 | Pancreatic secretion | 1.42E-03 | 5 | Q14643, P20020, P17252, P63092, P61586 | ITPR1, ATP2B1, PRKCA, GNAS, RHOA | More | | | Lamotrigine | hsa04978 | Mineral absorption | 3.94E-02 | 2 | P23634, Q9BXS9 | ATP2B4, SLC26A6 | More | | | Lamotrigine | hsa05012 | Parkinson disease | 1.77E-02 | 6 | P60604, P19174, P0DP23, Q71U36, Q13509, P68371 | UBE2G2, PLCG1, CALM1, TUBA1A, TUBB3, TUBB2C | More | | | Lamotrigine | hsa05014 | Amyotrophic lateral sclerosis | 4.31E-02 | 7 | O15399, P10415, Q13509, P68371, Q53GS7, P63261, Q9GZY0 | GRIN2D, BCL2, TUBB3, TUBB2C, GLE1, ACTG1, NXF2; NXF2B | More | | | Lamotrigine | hsa05031 | Amphetamine addiction | 1.61E-03 | 7 | O15399, P0DP23, Q16566, P22694, P18848, P17252, Q13547 | GRIN2D, CALM1, CAMK4, PRKACB, ATF4, PRKCA, HDAC1 | More | | | Lamotrigine | hsa05032 | Morphine addiction | 1.79E-05 | 8 | P62873, P63218, P50151, Q13370, P48169, P78334, P63092, P32298 | GNB1, GNG5, GNG10, PDE3B, GABRA4, GABRE, GNAS, GRK4 | More | | | Lamotrigine | hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 1.08E-02 | 4 | P25963, Q13488, P19174, P07948 | NFKBIA, TCIRG1, PLCG1, LYN | More | | | Lamotrigine | hsa05130 | Pathogenic Escherichia coli infection | 3.19E-02 | 6 | Q71U36, P16333, Q13509, P68371, Q14344, P25963 | TUBA1A, NCK1, TUBB3, TUBB2C, GNA13, NFKBIA | More | | | Lamotrigine | hsa05132 | Salmonella infection | 2.13E-05 | 17 | P51617, P25963, P08238, Q9UJU2, P63261, Q13546, Q13489, P10415, O75369, O60603, Q9BQS8, P51808, Q13561, Q71U36, Q13509, P68371, P49754 | IRAK1, NFKBIA, HSP90AB1, LEF1, ACTG1, RIPK1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DYNLT3, DCTN2, TUBA1A, TUBB3, TUBB2C, VPS41 | More | | | Lamotrigine | hsa05133 | Pertussis | 2.81E-03 | 4 | P0DP23, P23528, P09871, P0C0L4 | CALM1, CFL1, C1S, C4A | More | | | Lamotrigine | hsa05134 | Legionellosis | 4.75E-02 | 3 | P25963, P11215, P11142 | NFKBIA, ITGAM, HSPA8 | More | | | Lamotrigine | hsa05140 | Leishmaniasis | 2.02E-03 | 8 | P14598, P11215, P42224, O60603, P25963, P49006, P51617, Q15080 | NCF1, ITGAM, STAT1, TLR2, NFKBIA, MARCKSL1, IRAK1, NCF4 | More | | | Lamotrigine | hsa05142 | Chagas disease | 2.26E-02 | 3 | P01375, P30679, P48023 | TNF, GNA15, FASLG | More | | | Lamotrigine | hsa05143 | African trypanosomiasis | 1.51E-03 | 2 | P01375, P48023 | TNF, FASLG | More | | | Lamotrigine | hsa05144 | Malaria | 1.91E-02 | 3 | P01375, P35443, P26718 | TNF, THBS4, KLRK1 | More | | | Lamotrigine | hsa05146 | Amoebiasis | 2.41E-02 | 4 | P19875, P01375, P30679, P22694 | CXCL2, TNF, GNA15, PRKACB | More | | | Lamotrigine | hsa05150 | Staphylococcus aureus infection | 6.07E-04 | 5 | P0C0L4, P13646, P59665, P59666, P12838 | C4A, KRT13, DEFA1; DEFA1B, DEFA3, DEFA4 | More | | | Lamotrigine | hsa05160 | Hepatitis C | 1.27E-02 | 4 | P60033, P49841, P01375, P48023 | CD81, GSK3B, TNF, FASLG | More | | | Lamotrigine | hsa05163 | Human cytomegalovirus infection | 2.48E-04 | 11 | P25963, P62873, P63218, P50151, P0DP23, Q14344, P61586, P63092, P30101, P61769, P01568 | NFKBIA, GNB1, GNG5, GNG10, CALM1, GNA13, RHOA, GNAS, PDIA3, B2M, IFNA21 | More | | | Lamotrigine | hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 8.62E-05 | 10 | P01568, P42224, P25963, P62873, P63218, P50151, P19174, P07948, P04141, P0DP23 | IFNA21, STAT1, NFKBIA, GNB1, GNG5, GNG10, PLCG1, LYN, CSF2, CALM1 | More | | | Lamotrigine | hsa05168 | Herpes simplex virus 1 infection | 2.35E-03 | 15 | Q9UKJ0, P25963, P01568, Q9GZY0, P42224, Q07955, Q01130, Q13243, Q13489, P30101, Q13398, Q03923, O75820, Q9UDV6, P10415 | PILRB, NFKBIA, IFNA21, NXF2; NXF2B, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PDIA3, ZNF211, ZNF85, ZNF189, ZNF212, BCL2 | More | | | Lamotrigine | hsa05169 | Epstein-Barr virus infection | 2.54E-02 | 8 | Q92769, P04637, Q13546, P10415, P24522, O60603, P51617, P09693 | HDAC2, TP53, RIPK1, BCL2, GADD45A, TLR2, IRAK1, CD3G | More | | | Lamotrigine | hsa05170 | Human immunodeficiency virus 1 infection | 2.55E-04 | 16 | P62873, P63218, P50151, P0DP23, P17252, Q13546, P30101, Q14643, P01568, P51617, P25963, O60603, P19174, P09693, P10415, Q9Y6Q5 | GNB1, GNG5, GNG10, CALM1, PRKCA, RIPK1, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, PLCG1, CD3G, BCL2, AP1M2 | More | | | Lamotrigine | hsa05171 | Coronavirus disease - COVID-19 | 4.47E-02 | 2 | Q9UHA3, O14786 | RSL24D1, NRP1 | More | | | Lamotrigine | hsa05200 | Pathways in cancer | 1.17E-04 | 24 | P08238, P42224, P25963, P19174, Q9UJU2, P17252, P43246, P84022, Q13485, P20585, P14923, P10415, Q13489, P49767, P25116, P62873, P63218, P50151, Q14344, P78417, O75293, P0DP23, P01568, P14784 | HSP90AB1, STAT1, NFKBIA, PLCG1, LEF1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, JUP, BCL2, BIRC3, VEGFC, F2R, GNB1, GNG5, GNG10, GNA13, GSTO1, GADD45B, CALM1, IFNA21, IL2RB | More | | | Lamotrigine | hsa05205 | Proteoglycans in cancer | 3.68E-02 | 5 | P14780, P01375, P23588, Q13635, P22694 | MMP9, TNF, EIF4B, PTCH1, PRKACB | More | | | Lamotrigine | hsa05212 | Pancreatic cancer | 1.05E-02 | 4 | P42224, P37173, P84022, O75293 | STAT1, TGFBR2, SMAD3, GADD45B | More | | | Lamotrigine | hsa05214 | Glioma | 1.12E-04 | 7 | P0DP23, Q16566, P17252, P04637, P19174, P24522, O75293 | CALM1, CAMK4, PRKCA, TP53, PLCG1, GADD45A, GADD45B | More | | | Lamotrigine | hsa05216 | Thyroid cancer | 1.85E-02 | 3 | Q9UJU2, P04637, P24522 | LEF1, TP53, GADD45A | More | | | Lamotrigine | hsa05217 | Basal cell carcinoma | 4.42E-02 | 3 | Q9UJU2, P04637, P24522 | LEF1, TP53, GADD45A | More | | | Lamotrigine | hsa05321 | Inflammatory bowel disease | 1.91E-02 | 3 | P01375, Q14765, Q9UL17 | TNF, STAT4, TBX21 | More | | | Lamotrigine | hsa05330 | Allograft rejection | 1.51E-03 | 2 | P48023, P01375 | FASLG, TNF | More | | | Lamotrigine | hsa05332 | Graft-versus-host disease | 6.49E-05 | 4 | P48023, P01375, P26715, Q13241 | FASLG, TNF, KLRC1, KLRD1 | More | | | Lamotrigine | hsa05340 | Primary immunodeficiency | 1.58E-02 | 3 | P01730, P11912, Q8WV28 | CD4, CD79A, BLNK | More | | | Lamotrigine | hsa05412 | Arrhythmogenic right ventricular cardiomyopathy | 4.48E-02 | 1 | P54284 | CACNB3 | More | | | Lamotrigine | hsa05414 | Dilated cardiomyopathy | 4.55E-02 | 2 | P54284, P26678 | CACNB3, PLN | More | | | Lamotrigine | hsa05418 | Fluid shear stress and atherosclerosis | 2.31E-02 | 5 | P78417, P63261, P10415, P0DP23, Q92974 | GSTO1, ACTG1, BCL2, CALM1, ARHGEF2 | More | |
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