PharmaCoNets of L-lysine (SPCN: 2.65 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
L-Lysinehsa00630Glyoxylate and dicarboxylate metabolism7.59E-032P40925, P15104MDH1, GLULMore
L-Lysinehsa00970Aminoacyl-tRNA biosynthesis4.05E-022O95363, Q15046FARS2, KARSMore
L-Lysinehsa01523Antifolate resistance3.80E-022Q92820, P04818GGH, TYMSMore
L-Lysinehsa04062Chemokine signaling pathway4.62E-026P25024, P25025, P07948, P63218, P50151, P49407CXCR1, CXCR2, LYN, GNG5, GNG10, ARRB1More
L-Lysinehsa04110Cell cycle6.80E-036P06493, O75293, P30304, P33981, P42773, P01106CDK1, GADD45B, CDC25A, TTK, CDKN2C, MYCMore
L-Lysinehsa04218Cellular senescence4.79E-024P01106, O75293, P30304, P06493MYC, GADD45B, CDC25A, CDK1More
L-Lysinehsa04640Hematopoietic cell lineage3.69E-024P21926, P07766, P01730, P09564CD9, CD3E, CD4, CD7More
L-Lysinehsa04658Th1 and Th2 cell differentiation1.21E-025P07766, P01730, P06239, Q9UL17, Q13761CD3E, CD4, LCK, TBX21, RUNX3More
L-Lysinehsa04659Th17 cell differentiation6.89E-036P01730, P06239, P14778, Q9UL17, P08238, P07766CD4, LCK, IL1R1, TBX21, HSP90AB1, CD3EMore
L-Lysinehsa04662B cell receptor signaling pathway2.11E-024P60033, P07948, P21854, Q8N149CD81, LYN, CD72, LILRA2More
L-Lysinehsa04727GABAergic synapse2.62E-023P63218, P50151, P15104GNG5, GNG10, GLULMore
L-Lysinehsa04730Long-term depression4.05E-022Q14344, P07948GNA13, LYNMore
L-Lysinehsa05120Epithelial cell signaling in Helicobacter pylori infection4.95E-023P25024, P25025, P07948CXCR1, CXCR2, LYNMore
L-Lysinehsa05163Human cytomegalovirus infection2.46E-026P63218, P50151, Q14344, P14778, P25025, P30101GNG5, GNG10, GNA13, IL1R1, CXCR2, PDIA3More
L-Lysinehsa05216Thyroid cancer3.80E-022P01106, O75293MYC, GADD45BMore
L-Lysinehsa05223Non-small cell lung cancer1.39E-023P10826, Q9HC35, O75293RARB, EML4, GADD45BMore
L-Lysinehsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.09E-024P07766, P06239, Q9HC35, P01730CD3E, LCK, EML4, CD4More
L-Lysinehsa05340Primary immunodeficiency2.74E-044P01730, P11912, P07766, P06239CD4, CD79A, CD3E, LCKMore

Community members of L-lysine (SDC: 1.16)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)