PharmaCoNets of Ketamine (SPCN: 34.94 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Esketaminehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Esketaminehsa00310Lysine degradation1.53E-022Q96KQ7, P51648EHMT2, ALDH3A2More
Esketaminehsa00562Inositol phosphate metabolism2.54E-034P27987, Q13572, Q96PE3, P42338ITPKB, ITPK1, INPP4A, PIK3CBMore
Esketaminehsa02010ABC transporters2.29E-022P45844, P08183ABCG1, ABCB1More
Esketaminehsa03010Ribosome2.60E-088Q07020, P46778, P61513, Q02878, P35268, P63173, P27635, P62249RPL18, RPL21, RPL37A, RPL6, RPL22, RPL38, RPL10, RPS16More
Esketaminehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Esketaminehsa03040Spliceosome3.94E-048Q14562, O43143, O60508, P08579, P26368, Q13595, Q01130, O43447DHX8, DHX15, CDC40, SNRPB2, U2AF2, TRA2A, SFRS2, PPIHMore
Esketaminehsa04014Ras signaling pathway3.62E-025P42338, P49767, P0DP23, P63218, P50151PIK3CB, VEGFC, CALM1, GNG5, GNG10More
Esketaminehsa04020Calcium signaling pathway5.15E-058P27987, P21796, Q16566, P30679, O15399, P0DP23, P23634, P49767ITPKB, VDAC1, CAMK4, GNA15, GRIN2D, CALM1, ATP2B4, VEGFCMore
Esketaminehsa04024cAMP signaling pathway1.49E-025P42338, P0DP23, P23634, Q16566, O15399PIK3CB, CALM1, ATP2B4, CAMK4, GRIN2DMore
Esketaminehsa04070Phosphatidylinositol signaling system1.49E-035P0DP23, P42338, Q96PE3, Q13572, P27987CALM1, PIK3CB, INPP4A, ITPK1, ITPKBMore
Esketaminehsa04371Apelin signaling pathway7.45E-035P63218, P50151, Q13485, Q16566, P0DP23GNG5, GNG10, SMAD4, CAMK4, CALM1More
Esketaminehsa04613Neutrophil extracellular trap formation4.20E-025P04908, Q93077, P68431, O43315, Q16539H2AC4; H2AC8, HIST1H2AC, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, AQP9, MAPK14More
Esketaminehsa04664Fc epsilon RI signaling pathway2.32E-023P42338, P07948, P09917PIK3CB, LYN, ALOX5More
Esketaminehsa04666Fc gamma R-mediated phagocytosis4.10E-023P07948, P42338, P23528LYN, PIK3CB, CFL1More
Esketaminehsa04713Circadian entrainment8.43E-034O15399, P0DP23, P63218, P50151GRIN2D, CALM1, GNG5, GNG10More
Esketaminehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Esketaminehsa04720Long-term potentiation1.63E-023Q16566, P0DP23, O15399CAMK4, CALM1, GRIN2DMore
Esketaminehsa04724Glutamatergic synapse4.10E-023O15399, P63218, P50151GRIN2D, GNG5, GNG10More
Esketaminehsa04725Cholinergic synapse5.94E-034P63218, P50151, Q16566, P42338GNG5, GNG10, CAMK4, PIK3CBMore
Esketaminehsa04726Serotonergic synapse1.52E-024P63218, P50151, P33260, P09917GNG5, GNG10, CYP2C18, ALOX5More
Esketaminehsa04728Dopaminergic synapse4.47E-024P63218, P50151, P0DP23, O00327GNG5, GNG10, CALM1, ARNTLMore
Esketaminehsa04925Aldosterone synthesis and secretion3.14E-023P0DP23, Q16566, P23634CALM1, CAMK4, ATP2B4More
Esketaminehsa04926Relaxin signaling pathway5.70E-035P42338, P63218, P50151, P49767, P30679PIK3CB, GNG5, GNG10, VEGFC, GNA15More
Esketaminehsa04932Non-alcoholic fatty liver disease3.62E-023P49841, Q16718, O14521GSK3B, NDUFA5, SDHDMore
Esketaminehsa04976Bile secretion3.32E-022O43315, P08183AQP9, ABCB1More
Esketaminehsa05017Spinocerebellar ataxia5.94E-034Q8TB72, O15399, P42338, P21796PUM2, GRIN2D, PIK3CB, VDAC1More
Esketaminehsa05020Prion disease3.80E-024Q16718, O14521, P49841, Q16539NDUFA5, SDHD, GSK3B, MAPK14More
Esketaminehsa05022Pathways of neurodegeneration - multiple diseases1.24E-026P49841, Q16718, O14521, Q13561, Q16539, Q08752GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPIDMore
Esketaminehsa05034Alcoholism3.62E-025O15399, Q16566, P0DP23, P63218, P50151GRIN2D, CAMK4, CALM1, GNG5, GNG10More
Esketaminehsa05163Human cytomegalovirus infection4.19E-025P42338, P63218, P50151, P0DP23, P30101PIK3CB, GNG5, GNG10, CALM1, PDIA3More
Esketaminehsa05167Kaposi sarcoma-associated herpesvirus infection4.19E-025P42338, P63218, P50151, P07948, P0DP23PIK3CB, GNG5, GNG10, LYN, CALM1More
Esketaminehsa05170Human immunodeficiency virus 1 infection3.27E-026P42338, P63218, P50151, P0DP23, P30101, P23528PIK3CB, GNG5, GNG10, CALM1, PDIA3, CFL1More
Esketaminehsa05171Coronavirus disease - COVID-196.67E-088P62249, Q02878, P27635, Q07020, P46778, P35268, P61513, P63173RPS16, RPL6, RPL10, RPL18, RPL21, RPL22, RPL37A, RPL38More
Esketaminehsa05204Chemical carcinogenesis4.62E-022P78417, P33260GSTO1, CYP2C18More
Esketaminehsa05214Glioma2.32E-023P0DP23, Q16566, P42338CALM1, CAMK4, PIK3CBMore
Esketaminehsa05415Diabetic cardiomyopathy1.28E-024Q16718, O14521, Q16539, P49841NDUFA5, SDHD, MAPK14, GSK3BMore
Ketaminehsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Ketaminehsa00071Fatty acid degradation4.66E-023O75521, P11766, P33121ECI2, ADH5, ACSL1More
Ketaminehsa00190Oxidative phosphorylation2.29E-022Q16718, O14521NDUFA5, SDHDMore
Ketaminehsa00500Starch and sucrose metabolism9.22E-043O43451, P46976, P06737MGAM, GYG1, PYGLMore
Ketaminehsa00604Glycosphingolipid biosynthesis - ganglio series2.87E-033P06865, O15466, Q9H4F1HEXA, ST8SIA5, ST6GALNAC4More
Ketaminehsa00730Thiamine metabolism4.66E-022P05186, P24666ALPL, ACP1More
Ketaminehsa00770Pantothenate and CoA biosynthesis2.26E-043O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Ketaminehsa00970Aminoacyl-tRNA biosynthesis1.58E-044O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Ketaminehsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Ketaminehsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Ketaminehsa01240Biosynthesis of cofactors2.52E-022Q9BQB6, P14550VKORC1, AKR1A1More
Ketaminehsa01524Platinum drug resistance1.13E-025P10415, Q13489, P78417, P23025, P43246BCL2, BIRC3, GSTO1, XPA, MSH2More
Ketaminehsa02010ABC transporters2.29E-022P45844, P08183ABCG1, ABCB1More
Ketaminehsa03008Ribosome biogenesis in eukaryotes2.60E-035Q9NYH9, P78345, Q9BVP2, O15381, Q9GZY0UTP6, RPP38, GNL3, NVL, NXF2; NXF2BMore
Ketaminehsa03013RNA transport2.29E-0413O14980, P52298, Q09161, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, Q9Y6A5, P51114XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, TACC3, FXR1More
Ketaminehsa03022Basal transcription factors3.32E-022O00268, Q15544TAF4, TAF11More
Ketaminehsa03040Spliceosome5.79E-037Q14562, O43143, O60508, Q99633, Q13595, Q01130, Q9UMS4DHX8, DHX15, CDC40, PRPF18, TRA2A, SFRS2, PRPF19More
Ketaminehsa03410Base excision repair2.52E-022P49005, P29372POLD2, MPGMore
Ketaminehsa04015Rap1 signaling pathway1.58E-026P20827, P49767, P63261, P25116, P0DP23, P17252EFNA1, VEGFC, ACTG1, F2R, CALM1, PRKCAMore
Ketaminehsa04020Calcium signaling pathway1.16E-037Q16566, P17252, O15399, P25116, P0DP23, P23634, P49767CAMK4, PRKCA, GRIN2D, F2R, CALM1, ATP2B4, VEGFCMore
Ketaminehsa04024cAMP signaling pathway2.84E-025P0DP23, P23634, Q16566, O15399, P25116CALM1, ATP2B4, CAMK4, GRIN2D, F2RMore
Ketaminehsa04062Chemokine signaling pathway3.93E-0310P25024, P25025, P47992, Q9UBD3, P07948, P63218, P50151, P49407, Q08881, P49841CXCR1, CXCR2, XCL1, XCL2, LYN, GNG5, GNG10, ARRB1, ITK, GSK3BMore
Ketaminehsa04064NF-kappa B signaling pathway4.92E-026P10415, P51617, Q13546, Q9UDY8, Q13077, P24522BCL2, IRAK1, RIPK1, MALT1, TRAF1, GADD45AMore
Ketaminehsa04070Phosphatidylinositol signaling system4.07E-024P0DP23, Q14643, O14732, P17252CALM1, ITPR1, IMPA2, PRKCAMore
Ketaminehsa04071Sphingolipid signaling pathway9.73E-059P17252, P21453, Q9H228, P01375, Q13362, Q16537, Q9BX95, P04637, P10415PRKCA, S1PR1, EDG8, TNF, PPP2R5C, PPP2R5E, SGPP1, TP53, BCL2More
Ketaminehsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Ketaminehsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Ketaminehsa04145Phagosome1.86E-025P63261, Q15080, Q13509, P68371, P27824ACTG1, NCF4, TUBB3, TUBB2C, CANXMore
Ketaminehsa04217Necroptosis2.34E-024P01375, P48023, Q14765, Q99878TNF, FASLG, STAT4, H2AC14More
Ketaminehsa04261Adrenergic signaling in cardiomyocytes2.85E-039P07550, P22694, P18848, Q13362, Q16537, P0DP23, P17252, P10415, P20020ADRB2, PRKACB, ATF4, PPP2R5C, PPP2R5E, CALM1, PRKCA, BCL2, ATP2B1More
Ketaminehsa04350TGF-beta signaling pathway4.88E-021P37173TGFBR2More
Ketaminehsa04390Hippo signaling pathway1.47E-025P63261, Q13485, Q9UJU2, O43623, Q13489ACTG1, SMAD4, LEF1, SNAI2, BIRC3More
Ketaminehsa04510Focal adhesion3.21E-026Q15942, P17252, Q13489, P10415, P49767, P63261ZYX, PRKCA, BIRC3, BCL2, VEGFC, ACTG1More
Ketaminehsa04520Adherens junction3.36E-024Q13485, Q9UJU2, O43623, P63261SMAD4, LEF1, SNAI2, ACTG1More
Ketaminehsa04540Gap junction4.76E-023P17252, Q13509, P68371PRKCA, TUBB3, TUBB2CMore
Ketaminehsa04610Complement and coagulation cascades2.78E-031P0C0L4C4AMore
Ketaminehsa04612Antigen processing and presentation9.45E-059P13765, P48382, Q14953, P26715, P26717, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, KIR2DS5, KLRC1, KLRC2, KLRD1, KLRC4, CD8A, TNFMore
Ketaminehsa04613Neutrophil extracellular trap formation2.23E-0314P17252, O60603, P08246, Q92769, P04908, Q6FI13, Q93077, P33778, P68431, P14598, Q15080, P21462, O43315, Q16539PRKCA, TLR2, ELA2, HDAC2, H2AC4; H2AC8, H2AC18; H2AC19, HIST1H2AC, H2BC3, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, FPR1, AQP9, MAPK14More
Ketaminehsa04614Renin-angiotensin system1.52E-021P50052AGTR2More
Ketaminehsa04650Natural killer cell mediated cytotoxicity2.62E-0711P01375, P78314, P06239, O60880, P20963, Q13241, P26718, O75015, P26717, Q14953, P26715TNF, SH3BP2, LCK, SH2D1A, CD247, KLRD1, KLRK1, FCGR3B, KLRC2, KIR2DS5, KLRC1More
Ketaminehsa04657IL-17 signaling pathway2.41E-024P19875, P14780, P80188, P01375CXCL2, MMP9, LCN2, TNFMore
Ketaminehsa04660T cell receptor signaling pathway1.49E-0310P01375, O95267, Q08881, P20963, P09693, P01732, Q13191, P06239, Q16539, P49841TNF, RASGRP1, ITK, CD247, CD3G, CD8A, CBLB, LCK, MAPK14, GSK3BMore
Ketaminehsa04666Fc gamma R-mediated phagocytosis2.22E-024P49006, P06396, P14598, P17252MARCKSL1, GSN, NCF1, PRKCAMore
Ketaminehsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Ketaminehsa04714Thermogenesis5.21E-034Q16539, P33121, Q16718, O14521MAPK14, ACSL1, NDUFA5, SDHDMore
Ketaminehsa04720Long-term potentiation3.70E-045P17252, Q16566, P0DP23, O15399, Q14643PRKCA, CAMK4, CALM1, GRIN2D, ITPR1More
Ketaminehsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Ketaminehsa04728Dopaminergic synapse2.82E-026P14416, P63218, P50151, P49841, Q16539, P49407DRD2, GNG5, GNG10, GSK3B, MAPK14, ARRB1More
Ketaminehsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Ketaminehsa04742Taste transduction1.01E-021P30939HTR1FMore
Ketaminehsa04912GnRH signaling pathway4.42E-023P17252, Q14643, P0DP23PRKCA, ITPR1, CALM1More
Ketaminehsa04913Ovarian steroidogenesis2.54E-022P42330, P22694AKR1C3, PRKACBMore
Ketaminehsa04916Melanogenesis3.55E-023P0DP23, Q9UJU2, P17252CALM1, LEF1, PRKCAMore
Ketaminehsa04921Oxytocin signaling pathway4.19E-024P0DP23, P17252, Q16566, P63261CALM1, PRKCA, CAMK4, ACTG1More
Ketaminehsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Ketaminehsa04925Aldosterone synthesis and secretion2.90E-046Q14643, P0DP23, P17252, Q16566, P20020, P23634ITPR1, CALM1, PRKCA, CAMK4, ATP2B1, ATP2B4More
Ketaminehsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Ketaminehsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Ketaminehsa04932Non-alcoholic fatty liver disease2.44E-035P01375, P49841, P48023, Q16718, O14521TNF, GSK3B, FASLG, NDUFA5, SDHDMore
Ketaminehsa04933AGE-RAGE signaling pathway in diabetic complications3.36E-024Q13485, P10415, P49767, P17252SMAD4, BCL2, VEGFC, PRKCAMore
Ketaminehsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Ketaminehsa04966Collecting duct acid secretion9.34E-043P02730, P00918, Q9Y666SLC4A1, CA2, SLC12A7More
Ketaminehsa04970Salivary secretion4.63E-058P07550, P22694, Q14643, P20020, P23634, P17252, P0DP23, P49913ADRB2, PRKACB, ITPR1, ATP2B1, ATP2B4, PRKCA, CALM1, CAMPMore
Ketaminehsa04971Gastric acid secretion4.76E-023P17252, P63261, P0DP23PRKCA, ACTG1, CALM1More
Ketaminehsa04972Pancreatic secretion1.00E-023Q14643, P20020, P17252ITPR1, ATP2B1, PRKCAMore
Ketaminehsa04976Bile secretion3.32E-022O43315, P08183AQP9, ABCB1More
Ketaminehsa04978Mineral absorption3.94E-022P23634, Q9BXS9ATP2B4, SLC26A6More
Ketaminehsa05014Amyotrophic lateral sclerosis4.31E-027O15399, P10415, Q13509, P68371, Q53GS7, P63261, Q9GZY0GRIN2D, BCL2, TUBB3, TUBB2C, GLE1, ACTG1, NXF2; NXF2BMore
Ketaminehsa05020Prion disease3.80E-024Q16718, O14521, P49841, Q16539NDUFA5, SDHD, GSK3B, MAPK14More
Ketaminehsa05022Pathways of neurodegeneration - multiple diseases1.24E-026P49841, Q16718, O14521, Q13561, Q16539, Q08752GSK3B, NDUFA5, SDHD, DCTN2, MAPK14, PPIDMore
Ketaminehsa05031Amphetamine addiction1.61E-037O15399, P0DP23, Q16566, P22694, P18848, P17252, Q13547GRIN2D, CALM1, CAMK4, PRKACB, ATF4, PRKCA, HDAC1More
Ketaminehsa05120Epithelial cell signaling in Helicobacter pylori infection3.11E-024Q16539, P25024, P25025, P07948MAPK14, CXCR1, CXCR2, LYNMore
Ketaminehsa05132Salmonella infection2.12E-0413P51617, Q9UJU2, P63261, Q13546, Q13489, P10415, O75369, O60603, Q9BQS8, P51808, Q13561, Q13509, P68371IRAK1, LEF1, ACTG1, RIPK1, BIRC3, BCL2, FLNB, TLR2, FYCO1, DYNLT3, DCTN2, TUBB3, TUBB2CMore
Ketaminehsa05133Pertussis3.42E-034P0DP23, P23528, P09871, P0C0L4CALM1, CFL1, C1S, C4AMore
Ketaminehsa05135Yersinia infection4.65E-025P13612, P06239, Q16539, P01375, P49841ITGA4, LCK, MAPK14, TNF, GSK3BMore
Ketaminehsa05140Leishmaniasis1.56E-025P14598, O60603, P49006, P51617, Q15080NCF1, TLR2, MARCKSL1, IRAK1, NCF4More
Ketaminehsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Ketaminehsa05144Malaria1.03E-045P60033, O60603, P01375, P35443, P26718CD81, TLR2, TNF, THBS4, KLRK1More
Ketaminehsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Ketaminehsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Ketaminehsa05163Human cytomegalovirus infection1.72E-028P01375, P63218, P50151, P49841, P14778, P25025, Q16539, O00463TNF, GNG5, GNG10, GSK3B, IL1R1, CXCR2, MAPK14, TRAF5More
Ketaminehsa05168Herpes simplex virus 1 infection1.94E-029Q9UKJ0, P01568, Q9GZY0, Q01130, Q13489, Q13398, Q03923, Q9UDV6, P10415PILRB, IFNA21, NXF2; NXF2B, SFRS2, BIRC3, ZNF211, ZNF85, ZNF212, BCL2More
Ketaminehsa05169Epstein-Barr virus infection2.54E-028Q92769, P04637, Q13546, P10415, P24522, O60603, P51617, P09693HDAC2, TP53, RIPK1, BCL2, GADD45A, TLR2, IRAK1, CD3GMore
Ketaminehsa05170Human immunodeficiency virus 1 infection6.54E-039P0DP23, P17252, Q13546, Q14643, P51617, O60603, P09693, P10415, Q9Y6Q5CALM1, PRKCA, RIPK1, ITPR1, IRAK1, TLR2, CD3G, BCL2, AP1M2More
Ketaminehsa05200Pathways in cancer1.51E-0212Q9UJU2, P17252, P43246, Q13485, P14923, P10415, Q13489, P49767, P25116, P78417, P0DP23, P01568LEF1, PRKCA, MSH2, SMAD4, JUP, BCL2, BIRC3, VEGFC, F2R, GSTO1, CALM1, IFNA21More
Ketaminehsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Ketaminehsa05212Pancreatic cancer3.40E-021P37173TGFBR2More
Ketaminehsa05214Glioma8.71E-045P0DP23, Q16566, P17252, P04637, P24522CALM1, CAMK4, PRKCA, TP53, GADD45AMore
Ketaminehsa05216Thyroid cancer1.85E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Ketaminehsa05217Basal cell carcinoma4.42E-023Q9UJU2, P04637, P24522LEF1, TP53, GADD45AMore
Ketaminehsa05218Melanoma1.07E-023P09619, Q9GZP0, Q02750PDGFRB, PDGFD, MAP2K1More
Ketaminehsa05231Choline metabolism in cancer9.39E-034Q02750, P09619, Q9GZP0, O15245MAP2K1, PDGFRB, PDGFD, SLC22A1More
Ketaminehsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Ketaminehsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Ketaminehsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More
Ketaminehsa05412Arrhythmogenic right ventricular cardiomyopathy3.10E-023Q8IZS8, P54284, P13612CACNA2D3, CACNB3, ITGA4More
Ketaminehsa05414Dilated cardiomyopathy2.11E-024Q8IZS8, P54284, P13612, P26678CACNA2D3, CACNB3, ITGA4, PLNMore
Ketaminehsa05415Diabetic cardiomyopathy1.28E-024Q16718, O14521, Q16539, P49841NDUFA5, SDHD, MAPK14, GSK3BMore
Ketaminehsa05418Fluid shear stress and atherosclerosis2.49E-0311Q16539, P78417, P10599, P14780, P01375, P63261, P10415, P14778, P27930, P0DP23, Q92974MAPK14, GSTO1, TXN, MMP9, TNF, ACTG1, BCL2, IL1R1, IL1R2, CALM1, ARHGEF2More

Community members of Ketamine (SDC: 2.76)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P14416DRD2D(2) dopamine receptorReported00.060410.47792.5081
P30939HTR1F5Nonehydroxytryptamine receptor 1FReported00.000910.01982.0202
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P30531SLC6A1SodiumNone and chlorideNonedependent GABA transporter 1Predicted10.08890.52020.10471.1894
P48029SLC6A8SodiumNone and chlorideNonedependent creatine transporter 1Predicted10.21610.232800.5737
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
P50052AGTR2TypeNone2 angiotensin II receptorPredicted10.06040.43650.15411.0572
P21462FPR1fMetNoneLeuNonePhe receptorPredicted00.12050.34920.43781.1964
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P25024CXCR1CNoneXNoneC chemokine receptor type 1Predicted10.16560.42320.40091.33
P51684CCR6CNoneC chemokine receptor type 6Predicted00.0850.17410.33040.7212
P46091GPR1ChemerinNonelike receptor 2Predicted00.24760.137200.3982
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)