PharmaCoNets of Indoramin (SPCN: 278.61 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Indoraminhsa00020Citrate cycle (TCA cycle)3.41E-022P50213, O14521IDH3A, SDHDMore
Indoraminhsa00030Pentose phosphate pathway2.14E-074P60891, P51854, P52209, P37837PRPS1, TKTL1, PGD, TALDO1More
Indoraminhsa00040Pentose and glucuronate interconversions4.00E-021P15121AKR1B1More
Indoraminhsa00052Galactose metabolism1.06E-032P06280, O43451GLA, MGAMMore
Indoraminhsa00053Ascorbate and aldarate metabolism4.93E-021P14550AKR1A1More
Indoraminhsa00071Fatty acid degradation3.65E-034O75521, P00325, P11766, P33121ECI2, ADH1B, ADH5, ACSL1More
Indoraminhsa00072Synthesis and degradation of ketone bodies2.78E-021Q01581HMGCS1More
Indoraminhsa00190Oxidative phosphorylation1.69E-104Q16718, Q13488, P36542, O14521NDUFA5, TCIRG1, ATP5C1, SDHDMore
Indoraminhsa00220Arginine biosynthesis4.70E-073P15104, P05089, P49448GLUL, ARG1, GLUD2More
Indoraminhsa00230Purine metabolism4.02E-022P31350, P21589RRM2, NT5EMore
Indoraminhsa00240Pyrimidine metabolism2.54E-043P31350, P21589, P04818RRM2, NT5E, TYMSMore
Indoraminhsa00250Alanine, aspartate and glutamate metabolism1.34E-042P49448, P15104GLUD2, GLULMore
Indoraminhsa00310Lysine degradation2.59E-022Q96KQ7, P51648EHMT2, ALDH3A2More
Indoraminhsa00350Tyrosine metabolism3.40E-021P28332ADH6More
Indoraminhsa00380Tryptophan metabolism1.33E-022P46952, P51648HAAO, ALDH3A2More
Indoraminhsa00471D-Glutamine and D-glutamate metabolism1.65E-021P49448GLUD2More
Indoraminhsa00480Glutathione metabolism3.29E-044Q9UJ14, Q16772, P09211, P30041GGTL3, GSTA3, GSTP1, PRDX6More
Indoraminhsa00500Starch and sucrose metabolism3.18E-083O43451, P46976, P06737MGAM, GYG1, PYGLMore
Indoraminhsa00510N-Glycan biosynthesis1.13E-032P15907, Q9NR34ST6GAL1, MAN1C1More
Indoraminhsa00512Mucin type O-glycan biosynthesis3.19E-033O95395, Q8N4A0, Q9NY28GCNT3, GALNT4, GALNT8More
Indoraminhsa00520Amino sugar and nucleotide sugar metabolism1.04E-033Q16222, Q9Y223, P06865UAP1, GNE, HEXAMore
Indoraminhsa00524Neomycin, kanamycin and gentamicin biosynthesis2.03E-021P35557GCKMore
Indoraminhsa00533Glycosaminoglycan biosynthesis - keratan sulfate6.96E-041Q9NY97B3GNT2More
Indoraminhsa00562Inositol phosphate metabolism1.91E-023P27987, Q13572, Q96PE3ITPKB, ITPK1, INPP4AMore
Indoraminhsa00564Glycerophospholipid metabolism1.61E-023P23743, O14494, Q3LIE5DGKA, PLPP1, ADPRMMore
Indoraminhsa00565Ether lipid metabolism4.93E-021Q8N661TMEM86BMore
Indoraminhsa00590Arachidonic acid metabolism3.85E-022P11712, P09960CYP2C9, LTA4HMore
Indoraminhsa00591Linoleic acid metabolism4.07E-021P11712CYP2C9More
Indoraminhsa00600Sphingolipid metabolism2.65E-033Q9BX95, Q06136, P15289SGPP1, FVT1, ARSAMore
Indoraminhsa00601Glycosphingolipid biosynthesis - lacto and neolacto series3.78E-021Q9NY97B3GNT2More
Indoraminhsa00603Glycosphingolipid biosynthesis - globo and isoglobo series8.72E-032P06865, O75752HEXA, B3GALNT1More
Indoraminhsa00604Glycosphingolipid biosynthesis - ganglio series2.46E-022P06865, Q9H4F1HEXA, ST6GALNAC4More
Indoraminhsa00620Pyruvate metabolism3.90E-022P07195, P11766LDHB, ADH5More
Indoraminhsa00630Glyoxylate and dicarboxylate metabolism2.61E-054P40925, P40926, P05166, P15104MDH1, MDH2, PCCB, GLULMore
Indoraminhsa00640Propanoate metabolism3.83E-022Q02252, Q9P2R7ALDH6A1, SUCLA2More
Indoraminhsa00670One carbon pool by folate1.33E-022P04818, Q99707TYMS, MTRMore
Indoraminhsa00730Thiamine metabolism2.30E-083Q9Y6K8, P05186, P24666AK5, ALPL, ACP1More
Indoraminhsa00740Riboflavin metabolism1.42E-042P30043, P24666BLVRB, ACP1More
Indoraminhsa00770Pantothenate and CoA biosynthesis2.26E-043O95498, O95497, Q9NRN7VNN2, VNN1, AASDHPPTMore
Indoraminhsa00785Lipoic acid metabolism1.95E-031Q9Y234LIPT1More
Indoraminhsa00790Folate biosynthesis4.23E-044Q92820, P05186, P15121, P42330GGH, ALPL, AKR1B1, AKR1C3More
Indoraminhsa00830Retinol metabolism2.27E-035P00325, P11766, P00352, Q9BPW9, O75911ADH1B, ADH5, ALDH1A1, DHRS9, DHRS3More
Indoraminhsa00860Porphyrin and chlorophyll metabolism1.73E-032P36551, P30043CPOX, BLVRBMore
Indoraminhsa00900Terpenoid backbone biosynthesis9.84E-043Q01581, P49354, Q9UHG3HMGCS1, FNTA, PCYOX1More
Indoraminhsa00910Nitrogen metabolism1.34E-042P15104, P49448GLUL, GLUD2More
Indoraminhsa00970Aminoacyl-tRNA biosynthesis3.63E-074O95363, P54136, P14868, Q15046FARS2, RARS1, DARS, KARSMore
Indoraminhsa00980Metabolism of xenobiotics by cytochrome P4507.92E-075Q16772, P78417, P28332, P09211, P11712GSTA3, GSTO1, ADH6, GSTP1, CYP2C9More
Indoraminhsa00982Drug metabolism - cytochrome P4501.75E-055P11712, Q16772, P09211, P78417, P28332CYP2C9, GSTA3, GSTP1, GSTO1, ADH6More
Indoraminhsa00983Drug metabolism - other enzymes7.59E-066P04183, P20839, P32320, P05164, Q16772, P09211TK1, IMPDH1, CDA, MPO, GSTA3, GSTP1More
Indoraminhsa01100Metabolic pathways7.16E-0446Q9NR34, P35790, P05089, O14521, Q16772, P09211, Q9UJ14, P15144, P30041, O14732, P32320, P22748, P40926, P55809, P06280, Q16875, O43286, O43451, Q7KZN9, P05186, P24666, P15121, O60701, Q9HCC0, P33121, Q9UHK6, P42330, P51854, Q86VZ5, Q08477, Q96EB6, P15907, P57054, Q9UNP4, Q9BX95, P37837, P32321, P60891, Q9BPW9, O75911, Q9UHY7, P43490, P46976, P06737, Q9BQB6, Q16718MAN1C1, CHKA, ARG1, SDHD, GSTA3, GSTP1, GGTL3, ANPEP, PRDX6, IMPA2, CDA, CA4, MDH2, OXCT1, GLA, PFKFB3, B4GALT5, MGAM, COX15, ALPL, ACP1, AKR1B1, UGDH, MCCC2, ACSL1, AMACR, AKR1C3, TKTL1, SGMS1, CYP4F3, SIRT1, ST6GAL1, PIGP, ST3GAL5, SGPP1, TALDO1, DCTD, PRPS1, DHRS9, DHRS3, ENOPH1, PBEF1, GYG1, PYGL, VKORC1, NDUFA5More
Indoraminhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Indoraminhsa012102-Oxocarboxylic acid metabolism1.91E-021P50213IDH3AMore
Indoraminhsa01230Biosynthesis of amino acids1.72E-056P51854, P60891, Q99707, P50213, P15104, P37837TKTL1, PRPS1, MTR, IDH3A, GLUL, TALDO1More
Indoraminhsa01240Biosynthesis of cofactors2.01E-034P13716, Q9BQB6, P14550, P14618ALAD, VKORC1, AKR1A1, PKM2More
Indoraminhsa01521EGFR tyrosine kinase inhibitor resistance3.45E-044P49841, P04049, P08069, Q9NRA1GSK3B, RAF1, IGF1R, PDGFCMore
Indoraminhsa01522Endocrine resistance2.21E-037P14780, P22694, P04049, Q9UM47, P08069, P10415, Q13323MMP9, PRKACB, RAF1, NOTCH3, IGF1R, BCL2, BIKMore
Indoraminhsa01523Antifolate resistance3.15E-075P41440, Q92820, P04818, P01375, P18054SLC19A1, GGH, TYMS, TNF, ALOX12More
Indoraminhsa01524Platinum drug resistance4.44E-022Q16772, P09211GSTA3, GSTP1More
Indoraminhsa02010ABC transporters1.66E-043P45844, P08183, Q8IZY2ABCG1, ABCB1, ABCA7More
Indoraminhsa03008Ribosome biogenesis in eukaryotes1.88E-023O14980, O60832, Q9BVP2XPO1, DKC1, GNL3More
Indoraminhsa03010Ribosome6.70E-1218P62753, P25398, P32969, P40429, P62906, P62829, P46776, Q07020, P62888, P62899, P18077, P61927, P61513, P36578, P27635, P05386, P62249, P23396RPS6, RPS12, RPL9, RPL13A, RPL10A, RPL23, RPL27A, RPL18, RPL30, RPL31, RPL35A, RPL37, RPL37A, RPL4, RPL10, RPLP1, RPS16, RPS3More
Indoraminhsa03013RNA transport2.48E-1728P62826, O14980, P52298, Q09161, O14893, P61326, Q15287, Q9UBU9, Q7Z3B4, P35658, P63279, P68104, P47813, Q14152, P55884, O15371, O75822, P78345, Q9H777, P11940, P20042, Q14240, Q9BZI7, P23588, Q9Y6A5, Q14232, Q06787, P51114RAN, XPO1, NCBP2, NCBP1, GEMIN2, MAGOH, RNPS1, NXF1, NUP54, NUP214, UBE2I, EEF1A1, EIF1AX, EIF3A, EIF3B, EIF3D, EIF3J, RPP38, ELAC1, PABPC1, EIF2S2, EIF4A2, UPF3B, EIF4B, TACC3, EIF2B1, FMR1, FXR1More
Indoraminhsa03015mRNA surveillance pathway4.81E-022Q9BZI7, O94913UPF3B, PCF11More
Indoraminhsa03020RNA polymerase1.41E-136P30876, P24928, P62487, Q9GZM3, P52435, Q9Y535POLR2B, POLR2A, POLR2G, POLR2J2, POLR2J, POLR3HMore
Indoraminhsa03022Basal transcription factors2.97E-033P20226, O00268, Q15544TBP, TAF4, TAF11More
Indoraminhsa03040Spliceosome1.15E-1221Q14562, O43143, O60508, P17844, P08579, Q15427, P26368, O75940, P51991, P38159, P61978, O75494, Q13595, Q07955, Q01130, P84103, Q13243, P11142, Q9Y2W2, O43447, O75643DHX8, DHX15, CDC40, DDX5, SNRPB2, SF3B4, U2AF2, SMNDC1, HNRPA3, RBMX, HNRPK, FUSIP1, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8, WBP11, PPIH, ASCC3L1More
Indoraminhsa03050Proteasome1.53E-031P55036PSMD4More
Indoraminhsa03060Protein export6.62E-104Q15070, P37108, O76094, Q15005OXA1L, SRP14, SRP72, SPCS2More
Indoraminhsa03320PPAR signaling pathway5.20E-044Q6PCB7, O00767, Q9UNU6, Q02318SLC27A1, SCD, CYP8B1, CYP27A1More
Indoraminhsa03410Base excision repair1.11E-033P27695, P49005, P29372APEX1, POLD2, MPGMore
Indoraminhsa03430Mismatch repair4.38E-021P20585MSH3More
Indoraminhsa03450Non-homologous end-joining3.17E-032Q9NP87, P13010POLM, XRCC5More
Indoraminhsa04010MAPK signaling pathway1.69E-032P04049, P08069RAF1, IGF1RMore
Indoraminhsa04012ErbB signaling pathway1.13E-067P21860, P16333, Q13557, P19174, O14944, P01106, P04049ERBB3, NCK1, CAMK2D, PLCG1, EREG, MYC, RAF1More
Indoraminhsa04014Ras signaling pathway1.20E-0514P04049, P42338, P20827, Q9NRA1, P49767, P08069, Q13009, P17252, Q7LDG7, P0DP23, P62873, P63218, P50151, P19174RAF1, PIK3CB, EFNA1, PDGFC, VEGFC, IGF1R, TIAM1, PRKCA, RASGRP2, CALM1, GNB1, GNG5, GNG10, PLCG1More
Indoraminhsa04015Rap1 signaling pathway6.97E-0618P04049, P09603, P20827, Q9NRA1, P49767, Q9GZP0, P08069, P06213, Q96FS4, P11215, Q13009, O00522, Q7LDG7, P42338, P0DP23, Q86WV1, P17252, P19174RAF1, CSF1, EFNA1, PDGFC, VEGFC, PDGFD, IGF1R, INSR, SIPA1, ITGAM, TIAM1, KRIT1, RASGRP2, PIK3CB, CALM1, SKAP1, PRKCA, PLCG1More
Indoraminhsa04020Calcium signaling pathway5.05E-0919P27987, Q96DU7, Q08828, P45880, Q16566, Q13557, P17252, P21860, P30679, O15399, P19174, P0DP23, P0DP24, P05141, P51828, P20020, P23634, Q9NRA1, P49767ITPKB, ITPKC, ADCY1, VDAC2, CAMK4, CAMK2D, PRKCA, ERBB3, GNA15, GRIN2D, PLCG1, CALM1, CALM2, SLC25A5, ADCY7, ATP2B1, ATP2B4, PDGFC, VEGFCMore
Indoraminhsa04022cGMP-PKG signaling pathway2.34E-0613Q02153, P04049, Q99941, P18848, P23634, Q8WYR1, P31751, Q08828, P51828, P05141, P45880, P0DP24, P0DP23GUCY1B3, RAF1, CREBL1, ATF4, ATP2B4, PIK3R5, AKT2, ADCY1, ADCY7, SLC25A5, VDAC2, CALM2, CALM1More
Indoraminhsa04024cAMP signaling pathway1.09E-025Q08828, P51828, P31751, P0DP23, P04049ADCY1, ADCY7, AKT2, CALM1, RAF1More
Indoraminhsa04060Cytokine-cytokine receptor interaction5.34E-0311P14784, P27930, P14778, P26842, Q06643, Q13651, P25024, Q9UBD3, P47992, P09341, P01730IL2RB, IL1R2, IL1R1, CD27, LTB, IL10RA, CXCR1, XCL2, XCL1, CXCL1, CD4More
Indoraminhsa04061Viral protein interaction with cytokine and cytokine receptor2.92E-0611Q8NHW4, P09341, P19875, P25024, P02775, P25025, P47992, Q9UBD3, Q13651, P14784, P01375CCL4L2, CXCL1, CXCL2, CXCR1, PPBP, CXCR2, XCL1, XCL2, IL10RA, IL2RB, TNFMore
Indoraminhsa04062Chemokine signaling pathway1.70E-1024P25024, P25025, P09341, P19875, P47992, Q9UBD3, P09769, P07948, P42338, P19174, P62873, P63218, P50151, P43250, P49407, Q08881, Q7LDG7, Q13009, P14598, P42224, P04049, P25963, P49841, Q8WYR1CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, FGR, LYN, PIK3CB, PLCG1, GNB1, GNG5, GNG10, GRK6, ARRB1, ITK, RASGRP2, TIAM1, NCF1, STAT1, RAF1, NFKBIA, GSK3B, PIK3R5More
Indoraminhsa04064NF-kappa B signaling pathway1.67E-1825P10415, Q13489, P25963, P51617, O00463, P14778, P01584, P01375, P29965, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q8WV28, Q13315, P63279, P24522, Q8NHW4, P09341, P19875, Q06643, Q9NQC7BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, IL1R1, IL1B, TNF, CD40LG, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, BLNK, ATM, UBE2I, GADD45A, CCL4L2, CXCL1, CXCL2, LTB, CYLDMore
Indoraminhsa04066HIF-1 signaling pathway2.16E-021P08069IGF1RMore
Indoraminhsa04068FoxO signaling pathway3.80E-042P04049, P08069RAF1, IGF1RMore
Indoraminhsa04070Phosphatidylinositol signaling system1.05E-0711P19174, P0DP23, Q14643, O14986, P23743, Q86XP1, Q16760, P48426, P27987, Q96DU7, P17252PLCG1, CALM1, ITPR1, PIP5K1B, DGKA, DGKH, DGKD, PIP4K2A, ITPKB, ITPKC, PRKCAMore
Indoraminhsa04071Sphingolipid signaling pathway6.24E-1210P04049, P17252, P21453, Q9H228, P01375, Q13362, Q9BX95, Q16539, P10415, Q9UQC2RAF1, PRKCA, S1PR1, EDG8, TNF, PPP2R5C, SGPP1, MAPK14, BCL2, GAB2More
Indoraminhsa04072Phospholipase D signaling pathway2.43E-0412P04049, P31751, P42338, P43657, P25024, P25025, P19174, O14986, Q15438, Q08828, P51828, Q16760RAF1, AKT2, PIK3CB, P2RY5, CXCR1, CXCR2, PLCG1, PIP5K1B, PSCD1, ADCY1, ADCY7, DGKDMore
Indoraminhsa04080Neuroactive ligand-receptor interaction2.61E-0914P08311, P28472, Q15722, P21453, Q9H228, P43657, O00398, Q01726, P41968, P21462, P21730, Q16581, P07550, P35318CTSG, GABRB3, LTB4R, S1PR1, EDG8, P2RY5, P2RY10, MC1R, MC3R, FPR1, C5AR1, C3AR1, ADRB2, ADMMore
Indoraminhsa04110Cell cycle6.43E-089Q9UBD5, P06493, O60566, Q14683, O75293, P30304, P33981, P42773, P01106ORC3, CDK1, BUB1B, SMC1A, GADD45B, CDC25A, TTK, CDKN2C, MYCMore
Indoraminhsa04114Oocyte meiosis5.53E-1014Q9Y6D9, P51812, Q02750, Q9UJX4, P30260, P0DP23, P16298, Q17RY0, Q08828, P51828, Q16539, Q13362, Q14738, P08069MAD1L1, RPS6KA3, MAP2K1, ANAPC5, CDC27, CALM1, PPP3CB, CPEB4, ADCY1, ADCY7, MAPK14, PPP2R5C, PPP2R5D, IGF1RMore
Indoraminhsa04115p53 signaling pathway5.07E-037P24522, Q13315, P31350, Q53FA7, P06493, O95067, P10415GADD45A, ATM, RRM2, TP53I3, CDK1, CCNB2, BCL2More
Indoraminhsa04120Ubiquitin mediated proteolysis1.08E-036Q9UBT2, Q14145, Q13042, P62837, Q15751, Q14669SAE2, KEAP1, CDC16, UBE2D2, HERC1, TRIP12More
Indoraminhsa04136Autophagy - other3.71E-042O94817, Q9H1Y0ATG12, ATG5More
Indoraminhsa04140Autophagy - animal1.78E-0512P08069, P31751, P04049, Q7L523, O75460, P22694, Q14643, P10415, Q9H1Y0, Q04759, Q96GC9, Q8TEV9IGF1R, AKT2, RAF1, RRAGA, ERN1, PRKACB, ITPR1, BCL2, ATG5, PRKCQ, TMEM49, SMCR8More
Indoraminhsa04141Protein processing in endoplasmic reticulum3.70E-1016P18848, Q12933, P30101, Q15437, Q15436, P60604, Q99941, O75460, P11142, Q9H3Z4, P07900, P08238, Q9NR31, P14625, Q9H173, Q9UNL2ATF4, TRAF2, PDIA3, SEC23B, SEC23A, UBE2G2, CREBL1, ERN1, HSPA8, DNAJC5, HSP90AA1, HSP90AB1, SAR1A, HSP90B1, SIL1, SSR3More
Indoraminhsa04142Lysosome1.46E-0511Q99437, P25774, P06865, P22304, P38571, Q13510, Q9UJJ9, P07602, Q9NRA2, P49279, P61916ATP6V0B, CTSS, HEXA, IDS, LIPA, ASAH1, GNPTG, PSAP, SLC17A5, SLC11A1, NPC2More
Indoraminhsa04144Endocytosis8.41E-0716P40818, P0DMV8, P11142, Q9H444, O43633, O75351, P62491, Q96B97, P49407, Q15438, Q8WU79, Q14161, P14784, O95219, Q9UMY4, Q9Y5X3USP8, HSPA1A, HSPA8, CHMP4B, CHMP2A, VPS4B, RAB11A, SH3KBP1, ARRB1, PSCD1, SMAP1L, GIT2, IL2RB, SNX4, SNX12, SNX5More
Indoraminhsa04145Phagosome9.36E-1015O75015, P11215, Q15080, P14598, Q71U36, Q13509, P68371, Q13488, Q99437, P05164, P78380, O60603, P35443, P13765, P25774FCGR3B, ITGAM, NCF4, NCF1, TUBA1A, TUBB3, TUBB2C, TCIRG1, ATP6V0B, MPO, OLR1, TLR2, THBS4, HLA-DOB, CTSSMore
Indoraminhsa04146Peroxisome4.83E-024O96011, P56589, Q9UKG9, O75521PEX11B, PEX3, CROT, ECI2More
Indoraminhsa04150mTOR signaling pathway1.32E-035P08069, P04049, Q02750, Q9NQL2, P51812IGF1R, RAF1, MAP2K1, RRAGD, RPS6KA3More
Indoraminhsa04151PI3K-Akt signaling pathway2.43E-1137P62753, P42338, P21860, P43657, P25116, P01106, O43521, P27348, P09603, P20827, P49767, Q9GZP0, Q13362, P07900, P08238, P14625, Q8WYR1, P62873, P63218, P50151, P61952, P13612, P16144, O15335, Q16363, Q13751, P22105, O60603, P14784, P01568, Q99941, P18848, P10415, P17252, O00141, Q6ZUJ8, P30281RPS6, PIK3CB, ERBB3, P2RY5, F2R, MYC, BCL2L11, YWHAQ, CSF1, EFNA1, VEGFC, PDGFD, PPP2R5C, HSP90AA1, HSP90AB1, HSP90B1, PIK3R5, GNB1, GNG5, GNG10, GNG11, ITGA4, ITGB4, CHAD, LAMA4, LAMB3, TNXB, TLR2, IL2RB, IFNA21, CREBL1, ATF4, BCL2, PRKCA, SGK, PIK3AP1, CCND3More
Indoraminhsa04152AMPK signaling pathway2.07E-033P08069, Q96EB6, P36956IGF1R, SIRT1, SREBF1More
Indoraminhsa04210Apoptosis8.61E-0718Q13315, P04637, P10415, Q13489, O76075, P25963, P01375, Q9NR28, O75460, P24522, Q16548, Q13077, O43521, P43234, P18848, Q14643, P42575, P04049ATM, TP53, BCL2, BIRC3, DFFB, NFKBIA, TNF, DIABLO, ERN1, GADD45A, BCL2A1, TRAF1, BCL2L11, CTSO, ATF4, ITPR1, CASP2, RAF1More
Indoraminhsa04211Longevity regulating pathway3.68E-046P31751, P08069, Q08828, P51828, Q99941, P18848AKT2, IGF1R, ADCY1, ADCY7, CREBL1, ATF4More
Indoraminhsa04213Longevity regulating pathway - multiple species1.91E-059P31751, P42338, P08069, Q9Y4H2, Q08828, P51828, P0DMV8, P11142, Q13547AKT2, PIK3CB, IGF1R, IRS2, ADCY1, ADCY7, HSPA1A, HSPA8, HDAC1More
Indoraminhsa04215Apoptosis - multiple species1.56E-022Q13489, P10415BIRC3, BCL2More
Indoraminhsa04217Necroptosis5.18E-1625P01375, Q12933, P01568, P23458, P48023, Q13489, Q9NQC7, Q13546, P42224, Q14765, P07900, P08238, P15104, P05141, P01584, P0C0S5, Q6FI13, Q99878, Q93077, P10415, Q13557, Q9H444, O43633, O75351, Q08752TNF, TRAF2, IFNA21, JAK1, FASLG, BIRC3, CYLD, RIPK1, STAT1, STAT4, HSP90AA1, HSP90AB1, GLUL, SLC25A5, IL1B, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, BCL2, CAMK2D, CHMP4B, CHMP2A, VPS4B, PPIDMore
Indoraminhsa04218Cellular senescence8.08E-035P01106, P04049, O75293, P30304, P06493MYC, RAF1, GADD45B, CDC25A, CDK1More
Indoraminhsa04260Cardiac muscle contraction4.02E-022P09493, P14927TPM1, UQCRBMore
Indoraminhsa04261Adrenergic signaling in cardiomyocytes5.42E-0815P09493, P07550, Q08828, P51828, P22694, P31751, Q99941, P18848, Q13362, Q14738, P0DP23, Q13557, P17252, P10415, P23634TPM1, ADRB2, ADCY1, ADCY7, PRKACB, AKT2, CREBL1, ATF4, PPP2R5C, PPP2R5D, CALM1, CAMK2D, PRKCA, BCL2, ATP2B4More
Indoraminhsa04270Vascular smooth muscle contraction2.24E-0511P24723, Q04759, Q14643, P0DP23, P04049, Q08828, P51828, P22694, P35579, P35749, P35318PRKCH, PRKCQ, ITPR1, CALM1, RAF1, ADCY1, ADCY7, PRKACB, MYH9, MYH11, ADMMore
Indoraminhsa04310Wnt signaling pathway1.79E-022P17612, P67870PRKACA, CSNK2BMore
Indoraminhsa04330Notch signaling pathway4.34E-022Q92542, P46531NCSTN, NOTCH1More
Indoraminhsa04340Hedgehog signaling pathway6.08E-085P49841, P17612, P22694, Q13635, P10415GSK3B, PRKACA, PRKACB, PTCH1, BCL2More
Indoraminhsa04360Axon guidance1.39E-038P16333, P20827, O95631, P17252, P42338, P07332, P04049, P19174NCK1, EFNA1, NTN1, PRKCA, PIK3CB, FES, RAF1, PLCG1More
Indoraminhsa04370VEGF signaling pathway6.95E-104P16298, Q05397, Q02750, P04049PPP3CB, PTK2, MAP2K1, RAF1More
Indoraminhsa04371Apelin signaling pathway2.19E-0918P62873, P63218, P50151, P61952, Q8WYR1, P31751, P04049, Q08828, P51828, Q13370, Q14814, Q14344, Q13485, P84022, P62753, Q16566, P0DP23, P0DP24GNB1, GNG5, GNG10, GNG11, PIK3R5, AKT2, RAF1, ADCY1, ADCY7, PDE3B, MEF2D, GNA13, SMAD4, SMAD3, RPS6, CAMK4, CALM1, CALM2More
Indoraminhsa04380Osteoclast differentiation6.38E-0714Q9NQC7, Q9UQC2, Q16539, P23458, P06239, P31751, P01584, P14778, O75015, Q8WV28, P01375, Q15080, Q8N149, P78324CYLD, GAB2, MAPK14, JAK1, LCK, AKT2, IL1B, IL1R1, FCGR3B, BLNK, TNF, NCF4, LILRA2, SIRPAMore
Indoraminhsa04390Hippo signaling pathway3.80E-058P63261, P84022, Q13485, O15105, P04628, Q9UJU2, O43623, Q13489ACTG1, SMAD3, SMAD4, SMAD7, WNT1, LEF1, SNAI2, BIRC3More
Indoraminhsa04392Hippo signaling pathway - multiple species3.01E-021Q6V0I7FAT4More
Indoraminhsa04510Focal adhesion1.18E-032P04049, P08069RAF1, IGF1RMore
Indoraminhsa04512ECM-receptor interaction2.54E-047Q13751, P07359, P13612, P26012, P08514, O15335, P16070LAMB3, GP1BA, ITGA4, ITGB8, ITGA2B, CHAD, CD44More
Indoraminhsa04520Adherens junction8.29E-031P08069IGF1RMore
Indoraminhsa04530Tight junction3.00E-048Q8TEU7, P63261, P16989, P56750, O00501, Q92974, Q14247, P24844RAPGEF6, ACTG1, CSDA, CLDN17, CLDN5, ARHGEF2, CTTN, MYL9More
Indoraminhsa04540Gap junction3.86E-078P17252, P22694, Q13509, P68371, Q71U36, P04049, Q9NRA1, Q14643PRKCA, PRKACB, TUBB3, TUBB2C, TUBA1A, RAF1, PDGFC, ITPR1More
Indoraminhsa04550Signaling pathways regulating pluripotency of stem cells1.61E-035Q13873, P04049, Q02750, P08069, Q86SE9BMPR2, RAF1, MAP2K1, IGF1R, PCGF5More
Indoraminhsa04610Complement and coagulation cascades6.44E-114P09871, P00734, P0C0L4, P20023C1S, F2, C4A, CR2More
Indoraminhsa04611Platelet activation2.65E-056Q9Y490, P08514, Q15746, Q8WYR1, P17612, P07359TLN1, ITGA2B, MYLK, PIK3R5, PRKACA, GP1BAMore
Indoraminhsa04612Antigen processing and presentation3.18E-1211P13765, P48382, P01730, Q14953, P26715, P26717, Q07444, Q13241, O43908, P01732, P01375HLA-DOB, RFX5, CD4, KIR2DS5, KLRC1, KLRC2, KLRC3, KLRD1, KLRC4, CD8A, TNFMore
Indoraminhsa04613Neutrophil extracellular trap formation5.85E-1432P19174, P17252, P04049, P16109, P11215, O60603, P05164, P08246, Q9UM07, Q13547, Q92769, P04908, P0C0S5, Q6FI13, Q99878, Q93077, P62807, O60814, P68431, P14598, Q15080, P20160, P08311, P49913, O75015, P21730, P08514, P21462, P60709, P07359, O43315, Q16539PLCG1, PRKCA, RAF1, SELP, ITGAM, TLR2, MPO, ELA2, PADI4, HDAC1, HDAC2, H2AC4; H2AC8, H2AFZ, H2AC18; H2AC19, H2AC14, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, NCF1, NCF4, AZU1, CTSG, CAMP, FCGR3B, C5AR1, ITGA2B, FPR1, ACTB, GP1BA, AQP9, MAPK14More
Indoraminhsa04614Renin-angiotensin system2.74E-023P15144, P08311, O75787ANPEP, CTSG, ATP6AP2More
Indoraminhsa04620Toll-like receptor signaling pathway2.54E-033P01584, P31751, Q8NHW4IL1B, AKT2, CCL4L2More
Indoraminhsa04621NOD-like receptor signaling pathway2.71E-0616P01584, P07900, Q16539, Q14643, P25963, Q13489, P10599, Q9H1Y0, P43490, O00463, P10415, Q05823, P01375, P09341, P49913, P12838IL1B, HSP90AA1, MAPK14, ITPR1, NFKBIA, BIRC3, TXN, ATG5, PBEF1, TRAF5, BCL2, RNASEL, TNF, CXCL1, CAMP, DEFA4More
Indoraminhsa04623Cytosolic DNA-sensing pathway2.89E-116P01584, P01568, Q13546, P25963, Q9Y535, Q8NHW4IL1B, IFNA21, RIPK1, NFKBIA, POLR3H, CCL4L2More
Indoraminhsa04625C-type lectin receptor signaling pathway1.61E-0612Q9ULY5, P04049, P01584, Q9NQC7, P20749, Q14643, P01375, Q13191, P31751, P0DP24, P0DP23, Q16539CLEC4E, RAF1, IL1B, CYLD, BCL3, ITPR1, TNF, CBLB, AKT2, CALM2, CALM1, MAPK14More
Indoraminhsa04630JAK-STAT signaling pathway8.73E-034P31751, P23458, Q13651, P04049AKT2, JAK1, IL10RA, RAF1More
Indoraminhsa04640Hematopoietic cell lineage7.18E-1221P13612, P07359, P08514, P21926, P14778, P27930, P11215, P15144, P20023, P11836, P25063, P07766, P09693, P01732, P01730, P06127, P09564, P13765, P01375, P09603, P01584ITGA4, GP1BA, ITGA2B, CD9, IL1R1, IL1R2, ITGAM, ANPEP, CR2, MS4A1, CD24, CD3E, CD3G, CD8A, CD4, CD5, CD7, HLA-DOB, TNF, CSF1, IL1BMore
Indoraminhsa04650Natural killer cell mediated cytotoxicity1.03E-2119P16298, P50591, P19174, P01375, P78314, P06239, O60880, P20963, P42338, Q02750, P04049, Q13241, P26718, O14931, O75015, P26717, Q07444, Q14953, P26715PPP3CB, TNFSF10, PLCG1, TNF, SH3BP2, LCK, SH2D1A, CD247, PIK3CB, MAP2K1, RAF1, KLRD1, KLRK1, NCR3, FCGR3B, KLRC2, KLRC3, KIR2DS5, KLRC1More
Indoraminhsa04657IL-17 signaling pathway4.17E-1316P25963, P07900, P08238, O00463, Q12933, Q07955, Q16539, P49841, P09341, P19875, P14780, P04141, P80188, P01375, P06702, P01584NFKBIA, HSP90AA1, HSP90AB1, TRAF5, TRAF2, SFRS1, MAPK14, GSK3B, CXCL1, CXCL2, MMP9, CSF2, LCN2, TNF, S100A9, IL1BMore
Indoraminhsa04658Th1 and Th2 cell differentiation3.81E-2518P25963, Q04759, P07766, P20963, P09693, Q16539, P19174, P01730, P06239, P42224, Q14765, P23771, Q9UL17, P14784, Q9UM47, P13765, P23458, Q13761NFKBIA, PRKCQ, CD3E, CD247, CD3G, MAPK14, PLCG1, CD4, LCK, STAT1, STAT4, GATA3, TBX21, IL2RB, NOTCH3, HLA-DOB, JAK1, RUNX3More
Indoraminhsa04659Th17 cell differentiation1.16E-1721P25963, Q04759, Q16539, P19174, P01730, P06239, P42224, P14784, P13765, P14778, Q9HBE5, Q9UL17, P23771, P84022, Q13485, P01584, P08238, P07766, P09693, P20963, P23458NFKBIA, PRKCQ, MAPK14, PLCG1, CD4, LCK, STAT1, IL2RB, HLA-DOB, IL1R1, IL21R, TBX21, GATA3, SMAD3, SMAD4, IL1B, HSP90AB1, CD3E, CD3G, CD247, JAK1More
Indoraminhsa04660T cell receptor signaling pathway3.55E-2022P01375, P04141, P25963, Q9UDY8, Q04759, P42338, P10747, O95267, Q08881, P19174, P16333, P07766, P20963, P09693, P01730, P01732, Q13191, P06239, P29350, P04049, Q16539, P49841TNF, CSF2, NFKBIA, MALT1, PRKCQ, PIK3CB, CD28, RASGRP1, ITK, PLCG1, NCK1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK, PTPN6, RAF1, MAPK14, GSK3BMore
Indoraminhsa04662B cell receptor signaling pathway6.39E-059P42338, P20023, P60033, Q8WV28, P07948, P11912, P21854, Q8N149, P04049PIK3CB, CR2, CD81, BLNK, LYN, CD79A, CD72, LILRA2, RAF1More
Indoraminhsa04664Fc epsilon RI signaling pathway1.22E-069P01375, P04141, Q16539, P42338, Q9UQC2, P07948, P19174, P04049, P09917TNF, CSF2, MAPK14, PIK3CB, GAB2, LYN, PLCG1, RAF1, ALOX5More
Indoraminhsa04666Fc gamma R-mediated phagocytosis3.41E-026O75015, P04049, P06396, O14494, P14598, P17252FCGR3B, RAF1, GSN, PLPP1, NCF1, PRKCAMore
Indoraminhsa04668TNF signaling pathway9.42E-0915P01375, Q12933, O00463, Q13489, Q16539, P25963, Q99941, P18848, P19875, P01584, P20749, Q13077, P14780, P20333, O95429TNF, TRAF2, TRAF5, BIRC3, MAPK14, NFKBIA, CREBL1, ATF4, CXCL2, IL1B, BCL3, TRAF1, MMP9, TNFRSF1B, BAG4More
Indoraminhsa04670Leukocyte transendothelial migration4.20E-027P14780, Q96A32, P17252, P14598, Q15080, Q08881, P42681MMP9, MYLPF, PRKCA, NCF1, NCF4, ITK, TXKMore
Indoraminhsa04672Intestinal immune network for IgA production3.76E-033P29965, P10747, P13765CD40LG, CD28, HLA-DOBMore
Indoraminhsa04710Circadian rhythm4.40E-021O15516CLOCKMore
Indoraminhsa04713Circadian entrainment5.12E-0813P0DP23, P0DP24, Q13557, Q02153, P17252, P62873, P63218, P50151, P61952, Q14643, Q08828, P51828, O15055CALM1, CALM2, CAMK2D, GUCY1B3, PRKCA, GNB1, GNG5, GNG10, GNG11, ITPR1, ADCY1, ADCY7, PER2More
Indoraminhsa04714Thermogenesis6.09E-0410P22694, Q16539, P51828, Q969G3, P62753, P33121, P12074, O15239, Q16718, O14521PRKACB, MAPK14, ADCY7, SMARCE1, RPS6, ACSL1, COX6A1, NDUFA1, NDUFA5, SDHDMore
Indoraminhsa04720Long-term potentiation4.86E-0811P17252, Q13557, P16298, P0DP23, P0DP24, P51812, P18848, Q08828, Q02750, P04049, Q14643PRKCA, CAMK2D, PPP3CB, CALM1, CALM2, RPS6KA3, ATF4, ADCY1, MAP2K1, RAF1, ITPR1More
Indoraminhsa04721Synaptic vesicle cycle9.45E-042Q13488, P31645TCIRG1, SLC6A4More
Indoraminhsa04722Neurotrophin signaling pathway3.23E-046Q05655, P04049, P49841, O43524, P48023, P52566PRKCD, RAF1, GSK3B, FOXO3, FASLG, ARHGDIBMore
Indoraminhsa04723Retrograde endocannabinoid signaling1.69E-037Q14643, P17252, P62873, P61952, Q08828, O15239, Q16718ITPR1, PRKCA, GNB1, GNG11, ADCY1, NDUFA1, NDUFA5More
Indoraminhsa04724Glutamatergic synapse1.25E-079O15399, Q08828, P51828, P62873, P63218, P50151, P61952, P15104, Q9NSB8GRIN2D, ADCY1, ADCY7, GNB1, GNG5, GNG10, GNG11, GLUL, HOMER2More
Indoraminhsa04725Cholinergic synapse1.69E-0711Q08828, P51828, P22694, Q14643, P17252, P62873, P61952, P18848, Q13557, P31751, P10415ADCY1, ADCY7, PRKACB, ITPR1, PRKCA, GNB1, GNG11, ATF4, CAMK2D, AKT2, BCL2More
Indoraminhsa04726Serotonergic synapse5.74E-035P62873, P63218, P50151, P09917, P04049GNB1, GNG5, GNG10, ALOX5, RAF1More
Indoraminhsa04727GABAergic synapse1.25E-068Q08828, P51828, P62873, P63218, P50151, P61952, P15104, Q15111ADCY1, ADCY7, GNB1, GNG5, GNG10, GNG11, GLUL, PLCL1More
Indoraminhsa04728Dopaminergic synapse1.59E-0819Q14643, P17252, P14416, P62873, P63218, P50151, P61952, P31751, P49841, Q99941, P18848, Q16539, Q13557, P49407, Q13362, Q14738, P0DP23, P0DP24, O15516ITPR1, PRKCA, DRD2, GNB1, GNG5, GNG10, GNG11, AKT2, GSK3B, CREBL1, ATF4, MAPK14, CAMK2D, ARRB1, PPP2R5C, PPP2R5D, CALM1, CALM2, CLOCKMore
Indoraminhsa04730Long-term depression5.14E-054Q14344, P08069, P04049, P07948GNA13, IGF1R, RAF1, LYNMore
Indoraminhsa04740Olfactory transduction1.17E-034P62873, Q9H255, Q13557, P0DP24GNB1, OR51E2, CAMK2D, CALM2More
Indoraminhsa04742Taste transduction7.70E-042P30939, P17612HTR1F, PRKACAMore
Indoraminhsa04744Phototransduction1.17E-113P62873, P0DP23, P0DP24GNB1, CALM1, CALM2More
Indoraminhsa04750Inflammatory mediator regulation of TRP channels2.25E-0814P14778, P01584, Q08828, P51828, P22694, Q13557, Q16539, P19174, P42338, Q14643, P24723, Q04759, P0DP24, P0DP23IL1R1, IL1B, ADCY1, ADCY7, PRKACB, CAMK2D, MAPK14, PLCG1, PIK3CB, ITPR1, PRKCH, PRKCQ, CALM2, CALM1More
Indoraminhsa04810Regulation of actin cytoskeleton1.78E-026Q13009, P04049, P11215, P16144, P60709, P01042TIAM1, RAF1, ITGAM, ITGB4, ACTB, KNG1More
Indoraminhsa04910Insulin signaling pathway2.51E-034P22694, P06737, P04049, P49841PRKACB, PYGL, RAF1, GSK3BMore
Indoraminhsa04911Insulin secretion1.18E-095Q08828, P51828, Q99941, P18848, Q13557ADCY1, ADCY7, CREBL1, ATF4, CAMK2DMore
Indoraminhsa04912GnRH signaling pathway2.16E-0712P17252, Q08828, P51828, P18848, Q13557, Q16539, Q9Y6R4, Q14643, P0DP23, P0DP24, P22694, P04049PRKCA, ADCY1, ADCY7, ATF4, CAMK2D, MAPK14, MAP3K4, ITPR1, CALM1, CALM2, PRKACB, RAF1More
Indoraminhsa04913Ovarian steroidogenesis5.64E-054P42330, P22694, P06213, P08069AKR1C3, PRKACB, INSR, IGF1RMore
Indoraminhsa04914Progesterone-mediated oocyte maturation6.90E-099P08069, Q17RY0, Q9UJX4, P30260, Q9Y6D9, P51812, Q02750, Q16539, P04049IGF1R, CPEB4, ANAPC5, CDC27, MAD1L1, RPS6KA3, MAP2K1, MAPK14, RAF1More
Indoraminhsa04915Estrogen signaling pathway3.08E-0912P04049, Q99941, P18848, Q08828, P51828, P31751, P07900, P0DMV8, P11142, P0DP23, P0DP24, Q15788RAF1, CREBL1, ATF4, ADCY1, ADCY7, AKT2, HSP90AA1, HSPA1A, HSPA8, CALM1, CALM2, NCOA1More
Indoraminhsa04916Melanogenesis2.49E-046P0DP23, Q08828, P51828, P49841, Q01726, P04049CALM1, ADCY1, ADCY7, GSK3B, MC1R, RAF1More
Indoraminhsa04917Prolactin signaling pathway6.63E-031P04049RAF1More
Indoraminhsa04918Thyroid hormone synthesis2.03E-066Q08828, P51828, Q99941, P18848, P14625, P02768ADCY1, ADCY7, CREBL1, ATF4, HSP90B1, ALBMore
Indoraminhsa04919Thyroid hormone signaling pathway5.72E-0611P49841, P19174, P04049, P42224, P22694, P60709, Q13547, O60244, Q9NVC6, Q9UM47, P01106GSK3B, PLCG1, RAF1, STAT1, PRKACB, ACTB, HDAC1, MED14, MED17, NOTCH3, MYCMore
Indoraminhsa04920Adipocytokine signaling pathway5.72E-035P25963, P33121, Q04759, Q9Y4H2, P01375NFKBIA, ACSL1, PRKCQ, IRS2, TNFMore
Indoraminhsa04921Oxytocin signaling pathway2.32E-021P04049RAF1More
Indoraminhsa04922Glucagon signaling pathway7.76E-047P14618, P22694, P06737, Q12778, Q13370, P0DP23, Q14643PKM2, PRKACB, PYGL, FOXO1, PDE3B, CALM1, ITPR1More
Indoraminhsa04923Regulation of lipolysis in adipocytes6.16E-057Q08828, P51828, P07550, P06213, P42338, Q9Y4H2, P31751ADCY1, ADCY7, ADRB2, INSR, PIK3CB, IRS2, AKT2More
Indoraminhsa04924Renin secretion2.33E-095P22694, P07550, Q14643, Q13370, P0DP23PRKACB, ADRB2, ITPR1, PDE3B, CALM1More
Indoraminhsa04925Aldosterone synthesis and secretion1.07E-098Q99941, P18848, Q08828, P51828, P0DP23, P0DP24, Q13557, P23634CREBL1, ATF4, ADCY1, ADCY7, CALM1, CALM2, CAMK2D, ATP2B4More
Indoraminhsa04926Relaxin signaling pathway5.24E-0713P31751, P62873, P61952, Q99941, P18848, P22694, P14780, P02452, Q08828, P51828, P04049, P30679, P49407AKT2, GNB1, GNG11, CREBL1, ATF4, PRKACB, MMP9, COL1A1, ADCY1, ADCY7, RAF1, GNA15, ARRB1More
Indoraminhsa04927Cortisol synthesis and secretion1.28E-086Q14643, Q99941, P18848, Q08828, P51828, P22694ITPR1, CREBL1, ATF4, ADCY1, ADCY7, PRKACBMore
Indoraminhsa04928Parathyroid hormone synthesis, secretion and action3.61E-058Q14643, P51828, P22694, P23771, P04049, Q99941, P18848, P10415ITPR1, ADCY7, PRKACB, GATA3, RAF1, CREBL1, ATF4, BCL2More
Indoraminhsa04929GnRH secretion4.98E-031P04049RAF1More
Indoraminhsa04930Type II diabetes mellitus1.48E-032P06213, Q05655INSR, PRKCDMore
Indoraminhsa04931Insulin resistance1.94E-023P01375, P49841, P06737TNF, GSK3B, PYGLMore
Indoraminhsa04932Non-alcoholic fatty liver disease6.18E-1114P31751, P01375, P49841, O43521, P18848, P48023, O75460, P01584, P13073, P12074, O15239, Q16718, O95298, O14521AKT2, TNF, GSK3B, BCL2L11, ATF4, FASLG, ERN1, IL1B, COX4I1, COX6A1, NDUFA1, NDUFA5, NDUFC2, SDHDMore
Indoraminhsa04933AGE-RAGE signaling pathway in diabetic complications4.38E-069P84022, Q13485, P42224, P10415, P42338, Q12778, P49767, P17252, P19174SMAD3, SMAD4, STAT1, BCL2, PIK3CB, FOXO1, VEGFC, PRKCA, PLCG1More
Indoraminhsa04934Cushing syndrome2.23E-109Q14643, Q99941, P18848, Q08828, P51828, P22694, O15169, Q13557, P04628ITPR1, CREBL1, ATF4, ADCY1, ADCY7, PRKACB, AXIN1, CAMK2D, WNT1More
Indoraminhsa04935Growth hormone synthesis, secretion and action3.68E-046Q08828, P51828, P04049, Q99941, P18848, P31751ADCY1, ADCY7, RAF1, CREBL1, ATF4, AKT2More
Indoraminhsa04940Type I diabetes mellitus2.61E-034P10747, P48023, P13765, P01375CD28, FASLG, HLA-DOB, TNFMore
Indoraminhsa04950Maturity onset diabetes of the young2.03E-021P35557GCKMore
Indoraminhsa04960Aldosterone-regulated sodium reabsorption7.59E-032O00141, P06213SGK, INSRMore
Indoraminhsa04962Vasopressin-regulated water reabsorption1.80E-022P62491, P46459RAB11A, NSFMore
Indoraminhsa04964Proximal tubule bicarbonate reclamation3.18E-042P00918, P49448CA2, GLUD2More
Indoraminhsa04966Collecting duct acid secretion1.26E-043Q13488, P00918, Q9Y666TCIRG1, CA2, SLC12A7More
Indoraminhsa04970Salivary secretion9.17E-0910P07550, Q08828, P51828, P22694, Q14643, P17252, P0DP23, P0DP24, Q02153, P49913ADRB2, ADCY1, ADCY7, PRKACB, ITPR1, PRKCA, CALM1, CALM2, GUCY1B3, CAMPMore
Indoraminhsa04971Gastric acid secretion1.43E-055Q08828, P51828, P15311, P0DP23, Q13557ADCY1, ADCY7, VIL2, CALM1, CAMK2DMore
Indoraminhsa04973Carbohydrate digestion and absorption1.29E-022O43451, P42338MGAM, PIK3CBMore
Indoraminhsa04974Protein digestion and absorption3.03E-021P02452COL1A1More
Indoraminhsa04975Fat digestion and absorption3.43E-021O14494PLPP1More
Indoraminhsa04976Bile secretion7.42E-066O43315, Q08828, P51828, P22694, P08183, Q14032AQP9, ADCY1, ADCY7, PRKACB, ABCB1, BAATMore
Indoraminhsa05010Alzheimer disease1.30E-0628Q92542, Q16718, O95298, O14521, P05496, P13073, P12074, Q14643, O15399, Q00535, Q9NZJ5, O75460, P0DP23, P0DP24, Q13564, P01584, P18848, Q71U36, Q13509, P68371, O15169, P09603, P31751, P05141, P21796, P45880, Q08752, P28070NCSTN, NDUFA5, NDUFC2, SDHD, ATP5G1, COX4I1, COX6A1, ITPR1, GRIN2D, CDK5, EIF2AK3, ERN1, CALM1, CALM2, APPBP1, IL1B, ATF4, TUBA1A, TUBB3, TUBB2C, AXIN1, CSF1, AKT2, SLC25A5, VDAC1, VDAC2, PPID, PSMB4More
Indoraminhsa05012Parkinson disease4.00E-0618O15239, Q16718, O14521, P13073, P12074, P05496, P05141, P60604, O75460, P18848, Q14643, P19174, P0DP23, P0DP24, Q13557, Q71U36, Q13509, P68371NDUFA1, NDUFA5, SDHD, COX4I1, COX6A1, ATP5G1, SLC25A5, UBE2G2, ERN1, ATF4, ITPR1, PLCG1, CALM1, CALM2, CAMK2D, TUBA1A, TUBB3, TUBB2CMore
Indoraminhsa05014Amyotrophic lateral sclerosis2.72E-0210P01375, Q16718, O14521, P36542, P09651, Q7Z3B4, P35658, P43243, Q09161, Q16629TNF, NDUFA5, SDHD, ATP5C1, HNRNPA1, NUP54, NUP214, MATR3, NCBP1, SFRS7More
Indoraminhsa05016Huntington disease3.33E-0713O95298, P13073, P12074, Q9GZM3, P24928, P30876, P62487, P52435, P05141, O75460, P28070, P55036, O00232NDUFC2, COX4I1, COX6A1, POLR2J2, POLR2A, POLR2B, POLR2G, POLR2J, SLC25A5, ERN1, PSMB4, PSMD4, PSMD12More
Indoraminhsa05017Spinocerebellar ataxia3.94E-024O75460, P31751, P28070, P05141ERN1, AKT2, PSMB4, SLC25A5More
Indoraminhsa05020Prion disease2.60E-0722P01584, P46531, P11142, O15239, Q16718, O14521, P05496, P13073, P12074, Q92736, Q14643, P18848, P05141, P45880, O60282, Q13509, P68371, P49841, Q99941, P14598, Q15080, Q16539IL1B, NOTCH1, HSPA8, NDUFA1, NDUFA5, SDHD, ATP5G1, COX4I1, COX6A1, RYR2, ITPR1, ATF4, SLC25A5, VDAC2, KIF5C, TUBB3, TUBB2C, GSK3B, CREBL1, NCF1, NCF4, MAPK14More
Indoraminhsa05022Pathways of neurodegeneration - multiple diseases1.14E-0726Q14643, Q13509, P68371, P49841, P10415, Q16718, O95298, O14521, P13073, Q06055, Q8TEV9, O75460, P18848, Q13561, P19174, P05141, P17252, P20333, Q16539, Q00535, P01584, Q08752, O15020, P0DP23, P0DP24, P28070ITPR1, TUBB3, TUBB2C, GSK3B, BCL2, NDUFA5, NDUFC2, SDHD, COX4I1, ATP5G2, SMCR8, ERN1, ATF4, DCTN2, PLCG1, SLC25A5, PRKCA, TNFRSF1B, MAPK14, CDK5, IL1B, PPID, SPTBN2, CALM1, CALM2, PSMB4More
Indoraminhsa05030Cocaine addiction4.39E-032Q99941, P18848CREBL1, ATF4More
Indoraminhsa05031Amphetamine addiction6.70E-076P0DP24, Q13557, P22694, Q99941, P18848, Q13547CALM2, CAMK2D, PRKACB, CREBL1, ATF4, HDAC1More
Indoraminhsa05032Morphine addiction1.65E-066P62873, P63218, P50151, Q13370, Q07343, P43250GNB1, GNG5, GNG10, PDE3B, PDE4B, GRK6More
Indoraminhsa05033Nicotine addiction2.54E-022P28472, O15399GABRB3, GRIN2DMore
Indoraminhsa05034Alcoholism1.63E-0714Q99941, P18848, Q13547, P0DP23, P0DP24, P62873, P63218, P61952, P04049, P0C0S5, Q93077, P62807, O60814, P68431CREBL1, ATF4, HDAC1, CALM1, CALM2, GNB1, GNG5, GNG11, RAF1, H2AFZ, HIST1H2AC, HIST1H2BC, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12More
Indoraminhsa05100Bacterial invasion of epithelial cells2.85E-023Q14141, Q05397, Q96JJ3SEPT6, PTK2, ELMO2More
Indoraminhsa05110Vibrio cholerae infection3.23E-055Q13488, Q99437, P17252, P19174, P17612TCIRG1, ATP6V0B, PRKCA, PLCG1, PRKACAMore
Indoraminhsa05120Epithelial cell signaling in Helicobacter pylori infection6.14E-079Q16539, P25963, Q13488, P09341, P19875, P19174, P25024, P25025, P07948MAPK14, NFKBIA, TCIRG1, CXCL1, CXCL2, PLCG1, CXCR1, CXCR2, LYNMore
Indoraminhsa05130Pathogenic Escherichia coli infection1.69E-039Q71U36, P16333, Q13509, P68371, P60709, Q14344, P25963, P04406, P29350TUBA1A, NCK1, TUBB3, TUBB2C, ACTB, GNA13, NFKBIA, GAPDH, PTPN6More
Indoraminhsa05131Shigellosis6.29E-0416P01375, P25963, O00463, P68431, Q05655, Q04759, Q9UDY8, Q9H1Y0, Q14247, Q14643, Q12778, Q13315, P10415, Q08752, Q96A32, P07737TNF, NFKBIA, TRAF5, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, PRKCD, PRKCQ, MALT1, ATG5, CTTN, ITPR1, FOXO1, ATM, BCL2, PPID, MYLPF, PFN1More
Indoraminhsa05132Salmonella infection3.06E-1125P51617, P25963, P01375, P08238, P04049, Q9UJU2, P01106, P84095, P60709, O00471, Q13546, Q13489, P10415, P04406, O75369, P07737, Q96A32, O60603, Q9BQS8, Q13561, O60282, Q71U36, Q13509, P68371, P49754IRAK1, NFKBIA, TNF, HSP90AB1, RAF1, LEF1, MYC, RHOG, ACTB, EXOC5, RIPK1, BIRC3, BCL2, GAPDH, FLNB, PFN1, MYLPF, TLR2, FYCO1, DCTN2, KIF5C, TUBA1A, TUBB3, TUBB2C, VPS41More
Indoraminhsa05133Pertussis3.26E-052P0DP23, P0C0L4CALM1, C4AMore
Indoraminhsa05134Legionellosis8.14E-089P01584, P25963, Q9NR31, P11215, P68104, P0DMV8, P11142, P09341, P19875IL1B, NFKBIA, SAR1A, ITGAM, EEF1A1, HSPA1A, HSPA8, CXCL1, CXCL2More
Indoraminhsa05135Yersinia infection7.58E-049Q05397, P51812, P13612, P06239, Q16539, Q02750, P01375, P49841, Q96JJ3PTK2, RPS6KA3, ITGA4, LCK, MAPK14, MAP2K1, TNF, GSK3B, ELMO2More
Indoraminhsa05140Leishmaniasis2.26E-1816P13612, O75015, P14598, P11215, P23458, P42224, P13765, O60603, P25963, P01375, P01584, P29350, P49006, Q16539, P51617, Q15080ITGA4, FCGR3B, NCF1, ITGAM, JAK1, STAT1, HLA-DOB, TLR2, NFKBIA, TNF, IL1B, PTPN6, MARCKSL1, MAPK14, IRAK1, NCF4More
Indoraminhsa05143African trypanosomiasis1.11E-044P01375, P69905, P68871, P48023TNF, HBA2, HBB, FASLGMore
Indoraminhsa05144Malaria1.61E-108P60033, P69905, P68871, O60603, P01375, P35443, P01584, P26718CD81, HBA2, HBB, TLR2, TNF, THBS4, IL1B, KLRK1More
Indoraminhsa05145Toxoplasmosis1.55E-049P51617, P25963, P01375, P10415, Q13489, P42224, P13765, O60603, P29965IRAK1, NFKBIA, TNF, BCL2, BIRC3, STAT1, HLA-DOB, TLR2, CD40LGMore
Indoraminhsa05146Amoebiasis8.37E-1414P01584, P09341, P19875, P14778, P27930, P01375, O60603, P42338, P11215, P05089, P30679, P22694, P12814, P08311IL1B, CXCL1, CXCL2, IL1R1, IL1R2, TNF, TLR2, PIK3CB, ITGAM, ARG1, GNA15, PRKACB, ACTN1, CTSGMore
Indoraminhsa05150Staphylococcus aureus infection4.01E-0814P09871, P0C0L4, P21730, P21462, O75015, P13765, Q16581, P13646, Q14532, P16109, P59665, P59666, P12838, P49913C1S, C4A, C5AR1, FPR1, FCGR3B, HLA-DOB, C3AR1, KRT13, KRT32, SELP, DEFA1; DEFA1B, DEFA3, DEFA4, CAMPMore
Indoraminhsa05152Tuberculosis4.75E-0616P04049, Q13488, Q99437, P0DP23, O75015, P42224, P48382, O60603, P01375, P10415, P13765, P25774, P01568, P49913, Q9UDY8, P51617RAF1, TCIRG1, ATP6V0B, CALM1, FCGR3B, STAT1, RFX5, TLR2, TNF, BCL2, HLA-DOB, CTSS, IFNA21, CAMP, MALT1, IRAK1More
Indoraminhsa05160Hepatitis C1.98E-048P60033, O00501, P29728, P04049, P49841, P01375, P48023, P01106CD81, CLDN5, OAS2, RAF1, GSK3B, TNF, FASLG, MYCMore
Indoraminhsa05161Hepatitis B2.57E-0614P17252, P04049, P14780, Q99941, P18848, P25963, Q13485, P01375, P10415, P27348, P84022, P51617, O60603, Q14765PRKCA, RAF1, MMP9, CREBL1, ATF4, NFKBIA, SMAD4, TNF, BCL2, YWHAQ, SMAD3, IRAK1, TLR2, STAT4More
Indoraminhsa05162Measles3.18E-024P23458, P0DMV8, P01584, Q9NP90JAK1, HSPA1A, IL1B, RAB9BMore
Indoraminhsa05163Human cytomegalovirus infection8.50E-1129P31751, P04049, P01375, P25963, P62873, P63218, P50151, P61952, Q14643, P0DP23, P0DP24, Q14344, Q8NHW4, Q08828, P51828, P23458, P49841, P14778, P01584, Q13651, P25025, Q16539, Q99941, P18848, P04637, O00463, P30101, P61769, P01568AKT2, RAF1, TNF, NFKBIA, GNB1, GNG5, GNG10, GNG11, ITPR1, CALM1, CALM2, GNA13, CCL4L2, ADCY1, ADCY7, JAK1, GSK3B, IL1R1, IL1B, IL10RA, CXCR2, MAPK14, CREBL1, ATF4, TP53, TRAF5, PDIA3, B2M, IFNA21More
Indoraminhsa05164Influenza A1.49E-026P31751, P01584, P23458, P05141, P04049, Q9UBU9AKT2, IL1B, JAK1, SLC25A5, RAF1, NXF1More
Indoraminhsa05165Human papillomavirus infection3.10E-028P16144, Q05086, P01568, P42224, Q13488, Q13362, Q12778, Q13315ITGB4, UBE3A, IFNA21, STAT1, TCIRG1, PPP2R5C, FOXO1, ATMMore
Indoraminhsa05166Human T-cell leukemia virus 1 infection3.90E-027P23458, P05141, P62826, Q08828, P51828, P18848, P31751JAK1, SLC25A5, RAN, ADCY1, ADCY7, ATF4, AKT2More
Indoraminhsa05167Kaposi sarcoma-associated herpesvirus infection4.50E-1220P01568, P42224, P25963, P40189, P62873, P62879, P63218, P50151, P19875, P19174, P16298, Q14643, P04049, Q02750, P07948, P01106, P04141, P0DP23, P0CG47, Q9UJU2IFNA21, STAT1, NFKBIA, IL6ST, GNB1, GNB2, GNG5, GNG10, CXCL2, PLCG1, PPP3CB, ITPR1, RAF1, MAP2K1, LYN, MYC, CSF2, CALM1, UBB, LEF1More
Indoraminhsa05168Herpes simplex virus 1 infection1.54E-0619P25963, P01568, Q05823, Q9GZY0, P42224, Q07955, Q01130, Q13243, Q13489, P30101, Q9Y2A4, Q13398, P51522, Q9HCX3, P17038, Q03923, P52738, O75820, Q9UDV6NFKBIA, IFNA21, RNASEL, NXF2; NXF2B, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, PDIA3, ZNF443, ZNF211, ZNF83, ZNF304, ZNF43, ZNF85, ZNF140, ZNF189, ZNF212More
Indoraminhsa05169Epstein-Barr virus infection5.82E-0413P13765, P01106, Q13547, O00463, P07948, P30101, Q13761, P24522, O75293, P42224, P07766, P09693, P20963HLA-DOB, MYC, HDAC1, TRAF5, LYN, PDIA3, RUNX3, GADD45A, GADD45B, STAT1, CD3E, CD3G, CD247More
Indoraminhsa05170Human immunodeficiency virus 1 infection5.02E-0926P04049, Q02750, P62873, P62879, P63218, P50151, P16298, P0DP23, P01375, Q05397, P17252, O00463, P30101, Q14643, P01568, P51617, P25963, O60603, Q13315, O95067, P19174, P10415, Q13619, Q93034, Q9Y6Q5, P20333RAF1, MAP2K1, GNB1, GNB2, GNG5, GNG10, PPP3CB, CALM1, TNF, PTK2, PRKCA, TRAF5, PDIA3, ITPR1, IFNA21, IRAK1, NFKBIA, TLR2, ATM, CCNB2, PLCG1, BCL2, CUL4A, CUL5, AP1M2, TNFRSF1BMore
Indoraminhsa05171Coronavirus disease - COVID-198.28E-1026P01584, P25963, P42224, P01568, P23396, P62753, P25398, P62249, P40429, P62906, P36578, P32969, P27635, Q07020, P62888, P46776, P62899, P18077, P61927, P61513, P05386, P62829, P40189, P04141, P19174, P17252IL1B, NFKBIA, STAT1, IFNA21, RPS3, RPS6, RPS12, RPS16, RPL13A, RPL10A, RPL4, RPL9, RPL10, RPL18, RPL30, RPL27A, RPL31, RPL35A, RPL37, RPL37A, RPLP1, RPL23, IL6ST, CSF2, PLCG1, PRKCAMore
Indoraminhsa05200Pathways in cancer1.50E-0935Q13751, P42338, P08238, P42224, P25963, P19174, P01106, Q9UJU2, P17252, P43246, P84022, Q13485, P20585, Q13547, P14923, P30281, P10415, Q13489, P49767, P14921, Q12778, P43657, P25116, P62873, P63218, P50151, Q14344, Q7LDG7, Q9UM47, O75293, P0DP23, P01568, P14784, P40189, P01042LAMB3, PIK3CB, HSP90AB1, STAT1, NFKBIA, PLCG1, MYC, LEF1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, HDAC1, JUP, CCND3, BCL2, BIRC3, VEGFC, ETS1, FOXO1, P2RY5, F2R, GNB1, GNG5, GNG10, GNA13, RASGRP2, NOTCH3, GADD45B, CALM1, IFNA21, IL2RB, IL6ST, KNG1More
Indoraminhsa05202Transcriptional misregulation in cancer6.22E-1424Q12778, Q15532, Q13315, P41732, P17844, P14780, P27930, P14923, Q15744, Q16548, Q13489, Q13077, O15550, P08069, P35226, P05164, P12838, P08246, Q9C0K0, P41182, Q13547, Q92769, P12980, P24522FOXO1, SS18, ATM, TSPAN7, DDX5, MMP9, IL1R2, JUP, CEBPE, BCL2A1, BIRC3, TRAF1, UTX, IGF1R, BMI1, MPO, DEFA4, ELA2, BCL11B, BCL6, HDAC1, HDAC2, LYL1, GADD45AMore
Indoraminhsa05203Viral carcinogenesis1.65E-0613Q12933, Q99941, P18848, P42229, P06746, P27348, P29083, Q13547, Q15283, P12814, P61978, P62807, O60814TRAF2, CREBL1, ATF4, STAT5A, POLB, YWHAQ, GTF2E1, HDAC1, RASA2, ACTN1, HNRPK, HIST1H2BC, H2BC12More
Indoraminhsa05204Chemical carcinogenesis1.31E-054Q16772, P09211, P78417, P11712GSTA3, GSTP1, GSTO1, CYP2C9More
Indoraminhsa05205Proteoglycans in cancer7.26E-0514Q13009, O75369, P60709, P04049, P14780, P01106, P01375, P08069, P23588, P19174, Q13635, P22694, P29350, P08962TIAM1, FLNB, ACTB, RAF1, MMP9, MYC, TNF, IGF1R, EIF4B, PLCG1, PTCH1, PRKACB, PTPN6, CD63More
Indoraminhsa05206MicroRNAs in cancer1.09E-0413P30304, P09493, P15311, P21860, P01106, P61978, Q9Y4H2, P46531, Q13547, P63279, P22105, P19174, P04049CDC25A, TPM1, VIL2, ERBB3, MYC, HNRPK, IRS2, NOTCH1, HDAC1, UBE2I, TNXB, PLCG1, RAF1More
Indoraminhsa05210Colorectal cancer4.73E-048P84022, Q13485, P43246, P04049, P01106, P10415, P20585, O75293SMAD3, SMAD4, MSH2, RAF1, MYC, BCL2, MSH3, GADD45BMore
Indoraminhsa05211Renal cell carcinoma1.16E-021P04049RAF1More
Indoraminhsa05212Pancreatic cancer9.07E-069P42338, P31751, P04049, Q15311, P23458, P42224, P84022, Q13485, O75293PIK3CB, AKT2, RAF1, RALBP1, JAK1, STAT1, SMAD3, SMAD4, GADD45BMore
Indoraminhsa05213Endometrial cancer4.26E-033O15169, Q02750, P04049AXIN1, MAP2K1, RAF1More
Indoraminhsa05214Glioma4.30E-076P08069, P0DP23, P17252, P04049, P19174, O75293IGF1R, CALM1, PRKCA, RAF1, PLCG1, GADD45BMore
Indoraminhsa05215Prostate cancer2.56E-044P08069, P18848, P14625, P04049IGF1R, ATF4, HSP90B1, RAF1More
Indoraminhsa05216Thyroid cancer2.14E-034P01106, P04637, P24522, O75293MYC, TP53, GADD45A, GADD45BMore
Indoraminhsa05217Basal cell carcinoma1.64E-046Q13635, P04628, P49841, Q9UJU2, P04637, P24522PTCH1, WNT1, GSK3B, LEF1, TP53, GADD45AMore
Indoraminhsa05218Melanoma9.82E-054P08069, P04637, P04049, P24522IGF1R, TP53, RAF1, GADD45AMore
Indoraminhsa05219Bladder cancer5.65E-033P14780, P04637, P04049MMP9, TP53, RAF1More
Indoraminhsa05220Chronic myeloid leukemia1.61E-047Q13547, Q13485, P25963, P84022, P42338, P04049, O75293HDAC1, SMAD4, NFKBIA, SMAD3, PIK3CB, RAF1, GADD45BMore
Indoraminhsa05221Acute myeloid leukemia8.29E-031P04049RAF1More
Indoraminhsa05222Small cell lung cancer2.38E-036Q13489, P10415, P25963, Q13077, O00463, P24522BIRC3, BCL2, NFKBIA, TRAF1, TRAF5, GADD45AMore
Indoraminhsa05223Non-small cell lung cancer6.95E-044P10826, P04049, Q9HC35, O75293RARB, RAF1, EML4, GADD45BMore
Indoraminhsa05224Breast cancer2.75E-036P04049, P08069, P49841, Q92837, P04637, P24522RAF1, IGF1R, GSK3B, FRAT1, TP53, GADD45AMore
Indoraminhsa05225Hepatocellular carcinoma1.65E-042P04049, P08069RAF1, IGF1RMore
Indoraminhsa05226Gastric cancer2.93E-046P04049, Q02750, O15169, P84022, Q13485, P10415RAF1, MAP2K1, AXIN1, SMAD3, SMAD4, BCL2More
Indoraminhsa05230Central carbon metabolism in cancer9.95E-031P04049RAF1More
Indoraminhsa05231Choline metabolism in cancer5.27E-0711P04049, P31751, Q9NRA1, Q9Y259, P19174, P23743, P49619, Q16760, O14986, O14494, P17252RAF1, AKT2, PDGFC, CHKB, PLCG1, DGKA, DGKG, DGKD, PIP5K1B, PLPP1, PRKCAMore
Indoraminhsa05235PD-L1 expression and PD-1 checkpoint pathway in cancer1.94E-1018P25963, P42338, O95267, P19174, P07766, P20963, P09693, P06239, P29350, P04049, P23458, P42224, O60603, P10747, Q04759, Q16539, Q9HC35, P01730NFKBIA, PIK3CB, RASGRP1, PLCG1, CD3E, CD247, CD3G, LCK, PTPN6, RAF1, JAK1, STAT1, TLR2, CD28, PRKCQ, MAPK14, EML4, CD4More
Indoraminhsa05310Asthma9.97E-093P13765, P12724, P01375HLA-DOB, RNASE3, TNFMore
Indoraminhsa05320Autoimmune thyroid disease1.27E-034P13765, P29965, P01568, P10747HLA-DOB, CD40LG, IFNA21, CD28More
Indoraminhsa05321Inflammatory bowel disease1.51E-198O60603, P01375, P13765, Q14765, Q9UL17, P23771, P01584, Q9HBE5TLR2, TNF, HLA-DOB, STAT4, TBX21, GATA3, IL1B, IL21RMore
Indoraminhsa05322Systemic lupus erythematosus7.71E-0916O75015, P08246, P08311, P09871, P01375, P10747, P13765, P29965, Q6FI13, Q93077, P62807, Q16778, O60814, P68431, P12814, P05455FCGR3B, ELA2, CTSG, C1S, TNF, CD28, HLA-DOB, CD40LG, H2AC18; H2AC19, HIST1H2AC, HIST1H2BC, HIST2H2BE, H2BC12, H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12, ACTN1, SSBMore
Indoraminhsa05323Rheumatoid arthritis5.16E-045P13765, Q13488, P10747, P09341, O60603HLA-DOB, TCIRG1, CD28, CXCL1, TLR2More
Indoraminhsa05330Allograft rejection1.04E-035P13765, P29965, P48023, P10747, P01375HLA-DOB, CD40LG, FASLG, CD28, TNFMore
Indoraminhsa05332Graft-versus-host disease8.43E-156P13765, P48023, P10747, P01375, P26715, Q13241HLA-DOB, FASLG, CD28, TNF, KLRC1, KLRD1More
Indoraminhsa05340Primary immunodeficiency1.27E-056P01730, P01732, P11912, Q8WV28, P07766, P06239CD4, CD8A, CD79A, BLNK, CD3E, LCKMore
Indoraminhsa05410Hypertrophic cardiomyopathy1.73E-022P26012, P09493ITGB8, TPM1More
Indoraminhsa05412Arrhythmogenic right ventricular cardiomyopathy2.97E-053P54284, P15924, P26012CACNB3, DSP, ITGB8More
Indoraminhsa05414Dilated cardiomyopathy4.55E-022P54284, P26678CACNB3, PLNMore
Indoraminhsa05415Diabetic cardiomyopathy4.02E-0710P17252, P14598, Q15080, Q16718, O14521, Q92736, Q16539, P49841, P02452, P04406PRKCA, NCF1, NCF4, NDUFA5, SDHD, RYR2, MAPK14, GSK3B, COL1A1, GAPDHMore
Indoraminhsa05416Viral myocarditis2.62E-023P13765, P29965, P10747HLA-DOB, CD40LG, CD28More
Indoraminhsa05418Fluid shear stress and atherosclerosis1.79E-058Q16539, Q14145, P10599, P14780, P01375, P04637, P14778, P27930MAPK14, KEAP1, TXN, MMP9, TNF, TP53, IL1R1, IL1R2More

Community members of Indoramin (SDC: 13.03)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
P23458JAK1TyrosineNoneprotein kinase JAK1Predicted10.55460.921113.1195
P14780MMP9Matrix metalloproteinaseNone9Predicted10.16960.84240.73152.5012
P22894MMP8Neutrophil collagenasePredicted10.10610.35700.767
P14416DRD2D(2) dopamine receptorPredicted00.060410.47792.5081
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P49841GSK3BGlycogen synthase kinaseNone3 betaPredicted10.1678113.0839
P09874PARP1Poly [ADPNoneribose] polymerase 1Predicted10.553610.44822.725
P41968MC3RMelanocortin receptor 3Predicted10.22350.263700.6392
Q01726MC1RMelanocyteNonestimulating hormone receptorPredicted10.0470.23750.0110.5095
Q13547HDAC1Histone deacetylase 1Predicted00.044710.9863.0084
P31645SLC6A4SodiumNonedependent serotonin transporterPredicted00.047710.02032.0442
P61088UBE2NUbiquitinNoneconjugating enzyme E2 NPredicted00.11020.38250.37361.1937
P06213INSRInsulin receptorPredicted00.27940.78130.72092.4232
Q96RR4CAMKK2Calcium/calmodulinNonedependent protein kinase kinase 2Predicted00.36280.34060.46511.3277
P43490PBEF1Nicotinamide phosphoribosyltransferasePredicted10.44230.70640.2381.872
P09960LTA4HLeukotriene ANone4 hydrolasePredicted00.2770.95190.15652.1988
Q13546RIPK1ReceptorNoneinteracting serine/threonineNoneprotein kinase 1Predicted10.51990.41830.8431.9396
Q9UGN5PARP2Poly [ADPNoneribose] polymerase 2Predicted00.04350.26350.24610.7947
P30531SLC6A1SodiumNone and chlorideNonedependent GABA transporter 1Predicted10.08890.52020.10471.1894
Q16539MAPK14MitogenNoneactivated protein kinase 14Predicted10.0149113.0075
P27695APEX1DNANone(apurinic or apyrimidinic site) endonucleasePredicted10.4020.2210.12170.7647
Q08881ITKTyrosineNoneprotein kinase ITK/TSKPredicted10.16350.55450.4221.6127
Q92769HDAC2Histone deacetylase 2Predicted10.047310.9863.0097
P49354FNTAProtein farnesyltransferase/geranylgeranyltransferase typeNone1 subunit alphaPredicted00.53030.758801.7827
Q9GZT9EGLN1Egl nine homolog 1Predicted00.58040.60610.25561.7581
P08246ELA2Neutrophil elastasePredicted10.4960.68440.71322.33
P11712CYP2C9Cytochrome P450 2C9Predicted10.010610.15242.1577
P49336CDK8CyclinNonedependent kinase 8Predicted00.13560.64701.3618
P52732KIF11KinesinNonelike protein KIF11Predicted00.00820.828101.6602
P30530AXLTyrosineNoneprotein kinase receptor UFOPredicted10.37970.53650.16371.4264
P08183ABCB1ATPNonedependent translocase ABCB1Predicted10.078810.20522.2446
P17612PRKACAcAMPNonedependent protein kinase catalytic subunit alphaPredicted00.69370.525712.3982
P21453S1PR1Sphingosine 1Nonephosphate receptor 1Predicted10.14340.38470.2211.0621
Q16548BCL2A1BclNone2Nonerelated protein A1Predicted00.03060.03360.46870.5512
P40818USP8Ubiquitin carboxylNoneterminal hydrolase 8Predicted00.22780.02220.20360.362
Q07343PDE4BcAMPNonespecific 3',5'Nonecyclic phosphodiesterase 4BPredicted00.02530.99460.222.2219
P04818TYMSThymidylate synthasePredicted10.45530.27060.18930.9582
P25774CTSSCathepsin SPredicted00.31850.49320.51681.6625
O00767SCDStearoylNoneCoA desaturasePredicted10.16860.1870.19970.6581
P37840SNCAAlphaNonesynucleinPredicted10.08530.13240.33210.6395
P09619PDGFRBPlateletNonederived growth factor receptor betaPredicted00.04960.94440.74082.6543
Q13822ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase family member 2Predicted00.1130.3050.00630.6729
P15121AKR1B1AldoNoneketo reductase family 1 member B1Predicted10.56830.6290.2141.7562
Q9HB89NMUR1NeuromedinNoneU receptor 1Predicted00.00240.30300.6072
P09917ALOX5Polyunsaturated fatty acid 5NonelipoxygenasePredicted00.382210.27012.4612
O75460ERN1Serine/threonineNoneprotein kinase/endoribonuclease IRE1Predicted10.68060.29440.5571.4862
P17252PRKCAProtein kinase C alpha typePredicted00.14090.694812.4601
P43250GRK6G proteinNonecoupled receptor kinase 6Predicted10.15470.09550.29480.5632
Q15078CDK5R1CyclinNonedependent kinase 5 activator 1Predicted00.13580.50040.25751.3263
P06239LCKTyrosineNoneprotein kinase LckPredicted00.057610.72872.7575
O00141SGKSerine/threonineNoneprotein kinase Sgk1Predicted00.24130.30370.30591.034
P07947YES1TyrosineNoneprotein kinase YesPredicted00.12120.43450.1651.0947
Q86Z02HIPK1HomeodomainNoneinteracting protein kinase 1Predicted00.46310.28160.2181.0128
Q92630DYRK2Dual specificity tyrosineNonephosphorylationNoneregulated kinase 2Predicted00.17790.349400.7877
Q13627DYRK1ADual specificity tyrosineNonephosphorylationNoneregulated kinase 1APredicted00.0150.708201.4239
P49759CLK1Dual specificity protein kinase CLK1Predicted00.29680.45460.15871.2163
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
Q13557CAMK2DCalcium/calmodulinNonedependent protein kinase type II subunit deltaPredicted00.47780.3060.80951.6604
P00918CA2Carbonic anhydrase 2Predicted10.112510.22152.2778
O15294OGTUDPNoneNNoneacetylglucosamineNoneNonepeptide NNoneacetylglucosaminyltransferase 110 kDa subunitPredicted00.27390.06020.10210.3594
P25024CXCR1CNoneXNoneC chemokine receptor type 1Predicted10.16560.42320.40091.33
P21462FPR1fMetNoneLeuNonePhe receptorPredicted00.12050.34920.43781.1964
P08069IGF1RInsulinNonelike growth factor 1 receptorPredicted10.20820.95610.98833.0047
Q02750MAP2K1Dual specificity mitogenNoneactivated protein kinase kinase 1Predicted00.3120.512912.1819
P98170BIRC4E3 ubiquitinNoneprotein ligase XIAPPredicted00.29740.22980.791.3984
Q9P1W9PIM2Serine/threonineNoneprotein kinase pimNone2Predicted00.12670.76740.26381.8619
Q13370PDE3BcGMPNoneinhibited 3',5'Nonecyclic phosphodiesterase BPredicted00.09060.16140.35580.7239
Q05655PRKCDProtein kinase C delta typePredicted00.08160.41940.65441.5339
O60502MGEA5Protein ONoneGlcNAcasePredicted00.51010.04550.10570.4517
Q00535CDK5CyclinNonedependentNonelike kinase 5Predicted00.19920.66330.29941.7256
Q96EB6SIRT1NADNonedependent protein deacetylase sirtuinNone1Predicted10.28650.45710.57841.6358
P04637TP53Cellular tumor antigen p53Predicted10.10040.041711.1336
P25025CXCR2CNoneXNoneC chemokine receptor type 2Predicted10.02780.51890.44941.5011
P42330AKR1C3AldoNoneketo reductase family 1 member C3Predicted00.40170.83480.17482.0453
P06493CDK1CyclinNonedependent kinase 1Predicted00.01310.6042.6105
O14684PTGESProstaglandin E synthasePredicted10.45310.63580.15651.6547
P08238HSP90AB1Heat shock protein HSP 90NonebetaPredicted00.06110.52080.7411.8131
P09211GSTP1Glutathione SNonetransferase PPredicted00.32040.35230.45661.3213
P33981TTKDual specificity protein kinase TTKPredicted00.00390.58050.2591.422
Q15746MYLKMyosin light chain kinase, smooth musclePredicted00.04010.31160.42981.0731
P14625HSP90B1EndoplasminPredicted00.23360.14970.53840.9546
P07900HSP90AA1Heat shock protein HSP 90NonealphaPredicted10.47270.60640.7412.1901
P11511CYP19A1AromatasePredicted00.815610.15882.5666
P61073CXCR4CNoneXNoneC chemokine receptor type 4Predicted10.28230.40180.6481.5927
Q00536PCTK1CyclinNonedependent kinase 16Predicted00.27140.25600.6478
P19174PLCG11Nonephosphatidylinositol 4,5Nonebisphosphate phosphodiesterase gammaNone1Predicted00.06960.039711.1142
P21730C5AR1C5a anaphylatoxin chemotactic receptor 1Predicted10.02580.21670.53960.986
O75469NR1I2Nuclear receptor subfamily 1 group I member 2Predicted10.03150.949301.9143
P04049RAF1RAF protoNoneoncogene serine/threonineNoneprotein kinasePredicted10.5570.757212.7929
O75381PEX14Peroxisomal membrane protein PEX14Predicted00.19070.09950.10970.4039
P00734F2ProthrombinPredicted10.09630.7070.49771.9598
Q05397PTK2Focal adhesion kinase 1Predicted00.21530.58640.97132.2518
Q6PCB7SLC27A1LongNonechain fatty acid transport protein 1Predicted00.29150.07680.09920.3985
P30939HTR1F5Nonehydroxytryptamine receptor 1FPredicted00.000910.01982.0202
P07550ADRB2BetaNone2 adrenergic receptorPredicted00.007110.22052.224
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)