PharmaCoNets of Indigotindisulfonic-acid (SPCN: 9.68 )
Drug NamePathway IDPathway nameP-valueNo. of gene membersUniProt ACGene nameDetail of Coexpression
Indigotindisulfonic-acidhsa00030Pentose phosphate pathway3.06E-043P60891, P51854, P37837PRPS1, TKTL1, TALDO1More
Indigotindisulfonic-acidhsa00600Sphingolipid metabolism3.76E-021P15289ARSAMore
Indigotindisulfonic-acidhsa00770Pantothenate and CoA biosynthesis1.15E-022O95498, Q9NRN7VNN2, AASDHPPTMore
Indigotindisulfonic-acidhsa01200Carbon metabolism4.32E-023P51854, P37837, P60891TKTL1, TALDO1, PRPS1More
Indigotindisulfonic-acidhsa01230Biosynthesis of amino acids2.60E-023P51854, P60891, P37837TKTL1, PRPS1, TALDO1More
Indigotindisulfonic-acidhsa03430Mismatch repair4.38E-021P20585MSH3More
Indigotindisulfonic-acidhsa04015Rap1 signaling pathway9.14E-032P06213, O00522INSR, KRIT1More
Indigotindisulfonic-acidhsa04071Sphingolipid signaling pathway1.19E-024P21453, Q9H228, P01375, Q13362S1PR1, EDG8, TNF, PPP2R5CMore
Indigotindisulfonic-acidhsa04080Neuroactive ligand-receptor interaction1.97E-025P28472, P21453, Q9H228, P21730, P07550GABRB3, S1PR1, EDG8, C5AR1, ADRB2More
Indigotindisulfonic-acidhsa04120Ubiquitin mediated proteolysis3.44E-024Q14145, Q13042, P62837, Q15751KEAP1, CDC16, UBE2D2, HERC1More
Indigotindisulfonic-acidhsa04217Necroptosis2.34E-024P01375, P48023, Q14765, Q99878TNF, FASLG, STAT4, H2AC14More
Indigotindisulfonic-acidhsa04261Adrenergic signaling in cardiomyocytes2.95E-024P07550, P22694, P18848, Q13362ADRB2, PRKACB, ATF4, PPP2R5CMore
Indigotindisulfonic-acidhsa04612Antigen processing and presentation1.07E-036Q14953, P26715, P26717, Q13241, P01732, P01375KIR2DS5, KLRC1, KLRC2, KLRD1, CD8A, TNFMore
Indigotindisulfonic-acidhsa04650Natural killer cell mediated cytotoxicity5.05E-047P01375, P20963, Q13241, P26718, P26717, Q14953, P26715TNF, CD247, KLRD1, KLRK1, KLRC2, KIR2DS5, KLRC1More
Indigotindisulfonic-acidhsa04657IL-17 signaling pathway2.41E-024P19875, P14780, P80188, P01375CXCL2, MMP9, LCN2, TNFMore
Indigotindisulfonic-acidhsa04668TNF signaling pathway3.55E-024P01375, P18848, P19875, P14780TNF, ATF4, CXCL2, MMP9More
Indigotindisulfonic-acidhsa04722Neurotrophin signaling pathway3.27E-023P49841, O43524, P48023GSK3B, FOXO3, FASLGMore
Indigotindisulfonic-acidhsa04740Olfactory transduction2.52E-021Q9H255OR51E2More
Indigotindisulfonic-acidhsa04742Taste transduction1.01E-021P30939HTR1FMore
Indigotindisulfonic-acidhsa04913Ovarian steroidogenesis2.45E-033P42330, P22694, P06213AKR1C3, PRKACB, INSRMore
Indigotindisulfonic-acidhsa04923Regulation of lipolysis in adipocytes3.76E-021P06213INSRMore
Indigotindisulfonic-acidhsa04924Renin secretion4.04E-022P22694, P07550PRKACB, ADRB2More
Indigotindisulfonic-acidhsa04926Relaxin signaling pathway2.41E-024P18848, P22694, P14780, P30679ATF4, PRKACB, MMP9, GNA15More
Indigotindisulfonic-acidhsa04927Cortisol synthesis and secretion2.54E-022P18848, P22694ATF4, PRKACBMore
Indigotindisulfonic-acidhsa04930Type II diabetes mellitus3.14E-021P06213INSRMore
Indigotindisulfonic-acidhsa04932Non-alcoholic fatty liver disease2.74E-023P01375, P49841, P48023TNF, GSK3B, FASLGMore
Indigotindisulfonic-acidhsa04940Type I diabetes mellitus1.87E-022P48023, P01375FASLG, TNFMore
Indigotindisulfonic-acidhsa04960Aldosterone-regulated sodium reabsorption3.14E-021P06213INSRMore
Indigotindisulfonic-acidhsa04970Salivary secretion1.91E-023P07550, P22694, P49913ADRB2, PRKACB, CAMPMore
Indigotindisulfonic-acidhsa05031Amphetamine addiction4.32E-023P22694, P18848, Q13547PRKACB, ATF4, HDAC1More
Indigotindisulfonic-acidhsa05143African trypanosomiasis2.72E-022P01375, P48023TNF, FASLGMore
Indigotindisulfonic-acidhsa05144Malaria1.91E-023P01375, P35443, P26718TNF, THBS4, KLRK1More
Indigotindisulfonic-acidhsa05146Amoebiasis2.41E-024P19875, P01375, P30679, P22694CXCL2, TNF, GNA15, PRKACBMore
Indigotindisulfonic-acidhsa05160Hepatitis C1.27E-024P60033, P49841, P01375, P48023CD81, GSK3B, TNF, FASLGMore
Indigotindisulfonic-acidhsa05205Proteoglycans in cancer3.68E-025P14780, P01375, P23588, Q13635, P22694MMP9, TNF, EIF4B, PTCH1, PRKACBMore
Indigotindisulfonic-acidhsa05321Inflammatory bowel disease1.91E-023P01375, Q14765, Q9UL17TNF, STAT4, TBX21More
Indigotindisulfonic-acidhsa05330Allograft rejection2.72E-022P48023, P01375FASLG, TNFMore
Indigotindisulfonic-acidhsa05332Graft-versus-host disease7.27E-044P48023, P01375, P26715, Q13241FASLG, TNF, KLRC1, KLRD1More

Community members of Indigotindisulfonic-acid (SDC: 2.02)

UniProtACGene NameProtein NameReported/
Predicted		DisGeNETSPVSdrugabilitySHiSBiNSDisG
This pair is Reported in Drugbank.
Gene nameUniProt_IDBioactivityValue (nM)